diff --git a/python/podio/pythonizations/freeze_class.py b/python/podio/pythonizations/freeze_class.py
new file mode 100644
index 000000000..a3aeace00
--- /dev/null
+++ b/python/podio/pythonizations/freeze_class.py
@@ -0,0 +1,31 @@
+"""Prevent creating new attributes for existing objects
+The new attributes created in Python won't be visible for podio IO
+therefore preventing the addition of new attributes for podio objects
+might be desirable and help detecting mis-assignments"""
+
+from .utils.pythonizer import Pythonizer
+
+
+class FreezeClassPythonizer(Pythonizer):
+    """Prevent setting new attributes"""
+
+    @classmethod
+    def priority(cls):
+        """This most likely should be the last pythonization loaded
+        otherwise it may interfere with creating attributes during other pythonizations"""
+        return 99
+
+    @classmethod
+    def filter(cls, class_, name):
+        return True
+
+    @classmethod
+    def modify(cls, class_, name):
+        def freeze_setattr(self, attr, val):
+            object_type = type(self)
+            if attr not in object_type.__dict__:
+                raise AttributeError(f"'{object_type}' object has no attribute '{attr}'")
+            old_setattr(self, attr, val)
+
+        old_setattr = class_.__setattr__
+        class_.__setattr__ = freeze_setattr
diff --git a/python/podio/test_CodeGen.py b/python/podio/test_CodeGen.py
index 70bff5660..7545e834d 100644
--- a/python/podio/test_CodeGen.py
+++ b/python/podio/test_CodeGen.py
@@ -49,3 +49,15 @@ def test_bound_check(self):
         with self.assertRaises(IndexError):
             _ = collection[20]
         _ = collection[0]
+
+
+class AttributeCreationTest(unittest.TestCase):
+    """Setting new attributes test"""
+
+    def test_disable_new_attribute_creation(self):
+        component = nsp.AnotherNamespaceStruct()
+        self.assertEqual(component.x, 0)
+        component.x = 1
+        self.assertEqual(component.x, 1)
+        with self.assertRaises(AttributeError):
+            component.not_existing_attribute = 0
diff --git a/tests/datalayout.yaml b/tests/datalayout.yaml
index eb3e40c82..06cd5ebee 100644
--- a/tests/datalayout.yaml
+++ b/tests/datalayout.yaml
@@ -42,6 +42,11 @@ components :
     Members:
       - ex2::NamespaceStruct data
 
+  nsp::AnotherNamespaceStruct:
+    Members:
+      - int x
+      - int y
+
   StructWithFixedWithTypes:
     Members:
       - uint16_t fixedUnsigned16 // unsigned int with exactly 16 bits