diff --git a/setup.py b/setup.py
index cb3acc185..13f28323a 100644
--- a/setup.py
+++ b/setup.py
@@ -112,7 +112,7 @@ def run(self):
     "PyYAML>=6.0",
     "wrapt>=1.12",
     "resource-backed-dask-array>=0.1.0",
-    "tifffile>=2021.8.30,<2023.3.15",
+    "tifffile>=2021.8.30",
     "xarray>=0.16.1",
     "xmlschema",  # no pin because it's pulled in from OME types
     "zarr>=2.6,<2.16.0",