-
Notifications
You must be signed in to change notification settings - Fork 2
/
Copy pathadjacent-tissues-paper.html
403 lines (305 loc) · 44.4 KB
/
adjacent-tissues-paper.html
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8">
<meta name="viewport" content="width=device-width, initial-scale=1">
<title>Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments</title>
<script type="text/javascript">
function resizeIframe(iframe) {
var newheight;
var newwidth;
if (document.getElementById) {
newwidth = iframe.contentWindow.document.body.scrollWidth;
newheight = iframe.contentWindow.document.body.scrollHeight;
}
iframe.height = (newheight) + "px";
iframe.width = (newwidth) + "px";
}
</script>
<!-- Begin Jekyll SEO tag v2.8.0 -->
<title>Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments | CHTC</title>
<meta name="generator" content="Jekyll v4.3.4" />
<meta property="og:title" content="Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments" />
<meta name="author" content="Sarah Matysiak" />
<meta property="og:locale" content="en_US" />
<meta name="description" content="With this technique and the computing power of high throughput computing (HTC) combined, researchers can obtain thousands of simulations to study the pathology of tendons and ligaments." />
<meta property="og:description" content="With this technique and the computing power of high throughput computing (HTC) combined, researchers can obtain thousands of simulations to study the pathology of tendons and ligaments." />
<link rel="canonical" href="https://chtc.cs.wisc.edu/adjacent-tissues-paper.html" />
<meta property="og:url" content="https://chtc.cs.wisc.edu/adjacent-tissues-paper.html" />
<meta property="og:site_name" content="CHTC" />
<meta property="og:image" content="https://raw.githubusercontent.com/CHTC/Articles/main/images/jonblank.jpg" />
<meta property="og:image:alt" content="Jonathon Blank, a co-author of the paper" />
<meta property="og:type" content="article" />
<meta property="article:published_time" content="2023-11-27T00:00:00+00:00" />
<meta name="twitter:card" content="summary" />
<meta property="twitter:image" content="https://raw.githubusercontent.com/CHTC/Articles/main/images/jonblank.jpg" />
<meta name="twitter:image:alt" content="Jonathon Blank, a co-author of the paper" />
<meta property="twitter:title" content="Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments" />
<meta name="twitter:site" content="@chtc_uw" />
<meta name="twitter:creator" content="@Sarah Matysiak" />
<script type="application/ld+json">
{"@context":"https://schema.org","@type":"BlogPosting","author":{"@type":"Person","name":"Sarah Matysiak"},"dateModified":"2023-11-27T00:00:00+00:00","datePublished":"2023-11-27T00:00:00+00:00","description":"With this technique and the computing power of high throughput computing (HTC) combined, researchers can obtain thousands of simulations to study the pathology of tendons and ligaments.","headline":"Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments","image":{"alt":"Jonathon Blank, a co-author of the paper","url":"https://raw.githubusercontent.com/CHTC/Articles/main/images/jonblank.jpg","@type":"imageObject"},"mainEntityOfPage":{"@type":"WebPage","@id":"https://chtc.cs.wisc.edu/adjacent-tissues-paper.html"},"url":"https://chtc.cs.wisc.edu/adjacent-tissues-paper.html"}</script>
<!-- End Jekyll SEO tag -->
<script src="https://cdn.jsdelivr.net/npm/[email protected]/dist/js/bootstrap.min.js" integrity="sha384-cVKIPhGWiC2Al4u+LWgxfKTRIcfu0JTxR+EQDz/bgldoEyl4H0zUF0QKbrJ0EcQF" crossorigin="anonymous" defer></script>
<script type="text/javascript" src="/assets/js/uw-style.js" defer></script>
<script src="/assets/js/lunr.js" type="text/javascript" async></script>
<script type="text/javascript" src="/assets/js/search_bar.js" defer></script>
<script type="text/javascript" src="/assets/js/copy-content.js" defer></script>
<script type="text/javascript" src="/assets/js/main.js" defer></script>
<link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/[email protected]/font/bootstrap-icons.min.css">
<link type="text/css" href="/assets/fonts/fonts.0.0.1.css" rel="stylesheet">
<link type="text/css" href="/assets/css/style-v12.css" rel="stylesheet">
<script>(function(H){H.className=H.className.replace(/\bno-js\b/,'')})(document.documentElement)</script>
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
</head>
<body leftmargin="0" topmargin="0" marginwidth="0" marginheight="0">
<div class="container-fluid">
<div class="row justify-content-between bg-primary" role="navigation">
<div class="col-auto">
<a class="uw-global-name-link" href="http://www.wisc.edu" aria-label="University home page">U<span>niversity <span class="uw-of">of</span> </span>W<span>isconsin</span>–Madison</a>
</div>
<div class="col-auto">
<div class="row">
<div class="col-auto pe-0">
<a class="uw-global-name-link" href="/uw-research-computing" aria-label="UW Research Computing Homepage">Go to UW Research Computing Home</a>
</div>
<div class="col-auto d-flex">
<a class="btn-light px-2 my-auto rounded" href="/uw-research-computing/form.html">Request Account</a>
</div>
</div>
</div>
</div>
</div>
<button id="uw-top-menus-button" class="uw-mobile-menu-button-bar uw-mobile-menu-button-bar-reversed uw-is-closed" data-menu="uw-top-menus" aria-label="Open menu" aria-expanded="true" aria-controls="uw-top-menus">Menu<svg aria-hidden="true" focusable="false"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-menu"></use></svg><svg aria-hidden="true" focusable="false"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-close"></use></svg></button>
<div id="uw-top-menus" class="uw-is-visible uw-horizontal" aria-hidden="false">
<div class="uw-main-nav">
<nav class="uw-nav-menu uw-nav-menu-reverse" aria-label="Main Menu">
<ul id="uw-main-nav">
<div class="uw-header-crest">
<a href="/"><img class="uw-crest-svg py-2" src="/images/logos/CHTC_Logo_Full_Color.svg" alt="Link to CHTC Home Page"></a>
</div>
<li id="about" class="uw-dropdown">
<a href="/about.html" role="button" aria-haspopup="true" aria-expanded="false">
About
<svg aria-hidden="true" class="uw-caret" focusable="false">
<use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-down"></use>
</svg>
<svg aria-hidden="true" class="uw-caret" focusable="false">
<use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-caret-up"></use>
</svg>
</a>
<ul aria-hidden="true" aria-label="About submenu" class="uw-child-menu">
<li>
<a href="/htc.html">What is HTC?</a>
</li>
<li>
<a href="/approach.html">Our Approach</a>
</li>
<li>
<a href="/projects.html">Our Customers</a>
</li>
<li>
<a href="/people.html">Our Staff</a>
</li>
<li>
<a href="/jobs.html">Our Open Positions</a>
</li>
</ul>
<li id="uw-research-computing">
<a href="/uw-research-computing/index.html" aria-current="page">Research Computing</a>
</li>
<li id="technologies">
<a href="/technologies.html" aria-current="page">Technologies</a>
</li>
<li id="research">
<a href="/research.html" aria-current="page">Research</a>
</li>
<li id="news">
<a href="/news.html" aria-current="page">News</a>
</li>
<li id="events">
<a href="/events.html" aria-current="page">Events</a>
</li>
<li class="my-auto ms-auto me-0 pe-0">
<div id="main-search-bar" class="search-bar">
<input type="text" class="form-control" placeholder="Loading..." aria-describedby="button-addon2">
<div id="results-dropdown" class="results-dropdown w-100">
<div class="search-results" hidden></div>
</div>
</div>
</li>
</ul>
</nav>
</div>
</div>
<main id="main" style="min-height: 60vh;">
<main id="main" style="min-height: 60vh;">
<!-- This Layout is used for news articles. Different from character_optimized by adding author tags. -->
<div class="container-xxl">
<div class="row justify-content-center">
<div class="col-12 col-sm-11 col-md-9 col-lg-8">
<h1 class="uw-mini-bar mb-4">
Using HTC expanded scale of research using noninvasive measurements of tendons and ligaments
</h1>
<div class="text-dark d-flex flex-row justify-content-between mb-3">
<h4 class="mt-0">
Sarah Matysiak
</h4>
<h4 class="mt-0">
Nov 27, 2023
</h4>
</div>
<p><strong>With this technique and the computing power of high throughput computing (HTC) combined, researchers can obtain thousands of simulations to study the pathology of tendons
and ligaments.</strong></p>
<p>A recent paper published in the <a href="https://www.sciencedirect.com/science/article/abs/pii/S1751616123004915">Journal of the Mechanical Behavior of Biomedical Materials</a> by former Ph.D.
student in the Department of Mechanical Engineering (and current post-doctoral researcher at the University of Pennsylvania)
<a href="https://www.med.upenn.edu/orl/personnel/jonathon-blank-ph-d.html">Jonathon Blank</a> and John Bollinger Chair of Mechanical Engineering
<a href="https://directory.engr.wisc.edu/me/faculty/thelen_darryl/">Darryl Thelen</a> used the <a href="https://chtc.cs.wisc.edu/">Center for High Throughput Computing (CHTC)</a> to obtain their results.
Results that, Blank says, would not have been obtained at the same scale without HTC. “[This project], and a number of other projects, would have had a very small snapshot of the
problem at hand, which would not have allowed me to obtain the understanding of shear waves that I did. Throughout my time at UW, I ran tens of thousands of simulations — probably
even hundreds of thousands.”</p>
<figure class="figure float-end" style="margin-left: 1em; width: 250px;">
<img src="https://raw.githubusercontent.com/CHTC/Articles/main/images/jonblank.jpg" class="figure-img img-fluid rounded" alt="Post-doctoral researcher at the University of Pennsylvania Jonathon Blank." width="250px" />
<figcaption class="figure-caption">Post-doctoral researcher at the University of Pennsylvania Jonathon Blank.<br /></figcaption>
</figure>
<p>Using noninvasive sensors called shear wave tensiometers, researchers on this project applied HTC to study tendon structure and function. Currently, research in this field is hard
to translate because most assessments of tendon and ligament structure-function relationships are performed on the benchtop in a lab, Blank explains. To translate the benchtop
experiments into studying tendons in humans, the researchers use tensiometers as a measurement tool, and this study developed from trying to better understand these measurements
and how they can be applied to humans. “Tendons are very complex materials from an engineering perspective. When stretched, they can bear loads far exceeding your body weight, and
interestingly, even though they serve their roles in transmitting force from muscle to bone really well, the mechanisms that give rise to injury and pathology in these tissues aren’t
well understood.”</p>
<figure class="figure float-end" style="margin-left: 1em; width: 250px;">
<img src="https://raw.githubusercontent.com/CHTC/Articles/main/images/darrylthelen.jpg" class="figure-img img-fluid rounded" alt="John Bollinger Chair of Mechanical Engineering Darryl Thelen." width="250px" />
<figcaption class="figure-caption">John Bollinger Chair of Mechanical Engineering Darryl Thelen.<br /></figcaption>
</figure>
<p>In living organisms, researchers have used tensiometers to study the loading of muscles and tendons, including the triceps surae, which connects to the Achilles tendon, Blank notes.
Since humans are variable regarding the size, stiffness, composition, and length of their tendons or ligaments, it’s “challenging to use a model to accurately represent a parameter
space of human biomechanics in the real world. High throughput computing is particularly useful for our field just because we can readily express that variability at a large scale”
through HTC. With Thelen and Orthopedics and Rehabilitation assistant professor <a href="https://directory.engr.wisc.edu/me/Faculty/Roth_Josh/">Josh Roth</a>, Blank developed a pipeline for
simulating shear wave propagation in tendons and ligaments with HTC, which Blank and Thelen used in the paper.</p>
<p>With HTC, the researchers of this paper were able to further explore the mechanistic causes of changes in wave speed. “The advantage of this technique is being able to fully explore
an input space of different stiffnesses, geometries, microstructures, and applied forces. The advantage of the capabilities offered by the CHTC is that we can fill the entire input
space, not just between two data points, and thereby study changes in shear wave speed due to physiological factors and the mechanical underpinning driving those changes,” Blank
elaborates.</p>
<p>It wasn’t challenging to implement, Blank states, since facilitators were readily available to help and meet with him. When he first started using HTC, Blank attended the CHTC
office hours to get answers to his questions, even during COVID-19; during this time, there were also numerous one-on-one meetings. Having this backbone of support from the CHTC
research facilitators propelled Blank’s research and made it much easier. “For a lot of modeling studies, you’ll have this sparse input space where you change a couple of parameters
and investigate the sensitivity of your model that way. But it’s hard to interpret what goes on in between, so the CHTC quite literally saved me a lot of time. There were some
1,000 simulations in the paper, and HTC by scaling out the workload turned a couple thousand hours of simulation time into two or three hours of wall clock time. It’s a unique tool
for this kind of research.”</p>
<p>The next step from this paper’s findings, Blank describes, is providing subject-specific measurements of wave speeds. This involves “understanding if when we use a tensiometer on
someone’s Achilles tendon, for example, can we account for the tendon’s shape, size, injury status, etcetera — all of these variables matter when measuring shear wave speeds.”
Researchers from the lab can then use wearable tensiometers to measure tension in the Achilles and other tendons to study human movement in the real world.</p>
<p>From his CHTC-supported studies, Blank learned how to design computational research, diagnose different parameter spaces, and manage data. “For my field, it [HTC] is very important
because people are extremely variable — so our models should be too. The automation and capacity enabled by HTC makes it easy to understand whether our models are useful, and if
they are, how best to tune them to inform human biomechanics,” Blank says.</p>
</div>
</div>
</div>
</main>
</main>
<footer id="colophon" class="uw-footer">
<div class="uw-footer-content">
<div class="uw-logo">
<a href="http://www.wisc.edu" aria-label="Link to main university website">
<svg aria-hidden="true" focusable="false"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-crest-footer"></use></svg>
</a>
</div>
<div class="uw-footer-contact">
<h3 class="uw-footer-header">Contact Us</h3>
<ul class="uw-contact-list">
<li class="uw-contact-item">Office Hours: <a href="/uw-research-computing/get-help.html#office-hours">Tues: 10:30am-12pm; Thurs: 3-4:30pm</a></li>
<li class="uw-contact-item">Email: <a href="mailto:[email protected]">[email protected]</a></li>
<li class="uw-contact-item">Newsletter: <a href="/newsletter.html">Subscribe Now</a></li>
<li class="uw-contact-item">LinkedIn: <a href="https://www.linkedin.com/company/center-for-high-throughput-computing/">Website</a></li>
<li>
<ul class="uw-social-icons">
<li id="uw-icon-twitter" class="uw-social-icon">
<a aria-label="twitter" href="https://twitter.com/CHTC_UW"><svg aria-hidden="true" focusable="false"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#uw-symbol-twitter"></use></svg></a>
</li>
</ul>
</li>
</ul>
</div>
</div>
<div class="uw-copyright">
<p class="uw-contact-item">For all user support, questions, and comments: <a href="mailto:[email protected]">[email protected]</a></p>
<p>© 2022 Board of Regents of the <a href="http://www.wisconsin.edu">University of Wisconsin System</a></p>
</div>
</footer>
<!-- SVG icons -->
<svg aria-hidden="true" style="display: inline; height: 0; position: absolute;" xmlns:xlink="http://www.w3.org/1999/xlink">
<title>Site icons</title>
<defs>
<symbol id="uw-symbol-more" viewBox="0,0,1792,1792">
<title id="title">More</title>
<path d="M979 960q0 13-10 23l-466 466q-10 10-23 10t-23-10l-50-50q-10-10-10-23t10-23l393-393-393-393q-10-10-10-23t10-23l50-50q10-10 23-10t23 10l466 466q10 10 10 23zm384 0q0 13-10 23l-466 466q-10 10-23 10t-23-10l-50-50q-10-10-10-23t10-23l393-393-393-393q-10-10-10-23t10-23l50-50q10-10 23-10t23 10l466 466q10 10 10 23z"></path>
</symbol>
<symbol id="uw-symbol-menu" viewBox="0 0 1024 1024">
<title id="svg-menu">open menu</title>
<path class="path1" d="M128 256h768v86h-768v-86zM128 554v-84h768v84h-768zM128 768v-86h768v86h-768z"></path>
</symbol>
<symbol id="uw-symbol-close" viewBox="0 0 805 1024">
<title>close</title>
<path class="path1" d="M741.714 755.429q0 22.857-16 38.857l-77.714 77.714q-16 16-38.857 16t-38.857-16l-168-168-168 168q-16 16-38.857 16t-38.857-16l-77.714-77.714q-16-16-16-38.857t16-38.857l168-168-168-168q-16-16-16-38.857t16-38.857l77.714-77.714q16-16 38.857-16t38.857 16l168 168 168-168q16-16 38.857-16t38.857 16l77.714 77.714q16 16 16 38.857t-16 38.857l-168 168 168 168q16 16 16 38.857z"></path>
</symbol>
<symbol id="uw-symbol-search" viewBox="0 0 951 1024">
<title>search</title>
<path class="path1" d="M658.286 475.429q0-105.714-75.143-180.857t-180.857-75.143-180.857 75.143-75.143 180.857 75.143 180.857 180.857 75.143 180.857-75.143 75.143-180.857zM950.857 950.857q0 29.714-21.714 51.429t-51.429 21.714q-30.857 0-51.429-21.714l-196-195.429q-102.286 70.857-228 70.857-81.714 0-156.286-31.714t-128.571-85.714-85.714-128.571-31.714-156.286 31.714-156.286 85.714-128.571 128.571-85.714 156.286-31.714 156.286 31.714 128.571 85.714 85.714 128.571 31.714 156.286q0 125.714-70.857 228l196 196q21.143 21.143 21.143 51.429z"></path>
</symbol>
<symbol id="uw-symbol-search-gray" viewBox="0 0 951 1024">
<title>search</title>
<path class="path1" d="M658.286 475.429q0-105.714-75.143-180.857t-180.857-75.143-180.857 75.143-75.143 180.857 75.143 180.857 180.857 75.143 180.857-75.143 75.143-180.857zM950.857 950.857q0 29.714-21.714 51.429t-51.429 21.714q-30.857 0-51.429-21.714l-196-195.429q-102.286 70.857-228 70.857-81.714 0-156.286-31.714t-128.571-85.714-85.714-128.571-31.714-156.286 31.714-156.286 85.714-128.571 128.571-85.714 156.286-31.714 156.286 31.714 128.571 85.714 85.714 128.571 31.714 156.286q0 125.714-70.857 228l196 196q21.143 21.143 21.143 51.429z"></path>
</symbol>
<symbol id="uw-symbol-search-in-blank" viewBox="0 0 951 1024">
<title>search</title>
<path class="path1" d="M658.286 475.429q0-105.714-75.143-180.857t-180.857-75.143-180.857 75.143-75.143 180.857 75.143 180.857 180.857 75.143 180.857-75.143 75.143-180.857zM950.857 950.857q0 29.714-21.714 51.429t-51.429 21.714q-30.857 0-51.429-21.714l-196-195.429q-102.286 70.857-228 70.857-81.714 0-156.286-31.714t-128.571-85.714-85.714-128.571-31.714-156.286 31.714-156.286 85.714-128.571 128.571-85.714 156.286-31.714 156.286 31.714 128.571 85.714 85.714 128.571 31.714 156.286q0 125.714-70.857 228l196 196q21.143 21.143 21.143 51.429z"></path>
</symbol>
<symbol id="uw-symbol-envelope" viewBox="0 0 1024 1024">
<title>envelope</title>
<path class="path1" d="M1024 405.714v453.714q0 37.714-26.857 64.571t-64.571 26.857h-841.143q-37.714 0-64.571-26.857t-26.857-64.571v-453.714q25.143 28 57.714 49.714 206.857 140.571 284 197.143 32.571 24 52.857 37.429t54 27.429 62.857 14h1.143q29.143 0 62.857-14t54-27.429 52.857-37.429q97.143-70.286 284.571-197.143 32.571-22.286 57.143-49.714zM1024 237.714q0 45.143-28 86.286t-69.714 70.286q-214.857 149.143-267.429 185.714-5.714 4-24.286 17.429t-30.857 21.714-29.714 18.571-32.857 15.429-28.571 5.143h-1.143q-13.143 0-28.571-5.143t-32.857-15.429-29.714-18.571-30.857-21.714-24.286-17.429q-52-36.571-149.714-104.286t-117.143-81.429q-35.429-24-66.857-66t-31.429-78q0-44.571 23.714-74.286t67.714-29.714h841.143q37.143 0 64.286 26.857t27.143 64.571z"></path>
</symbol>
<symbol id="uw-symbol-pinterest" class="uw-social-symbols" viewBox="0 0 731 1024">
<title>pinterest-p</title>
<path class="path1" d="M0 341.143q0-61.714 21.429-116.286t59.143-95.143 86.857-70.286 105.714-44.571 115.429-14.857q90.286 0 168 38t126.286 110.571 48.571 164q0 54.857-10.857 107.429t-34.286 101.143-57.143 85.429-82.857 58.857-108 22q-38.857 0-77.143-18.286t-54.857-50.286q-5.714 22.286-16 64.286t-13.429 54.286-11.714 40.571-14.857 40.571-18.286 35.714-26.286 44.286-35.429 49.429l-8 2.857-5.143-5.714q-8.571-89.714-8.571-107.429 0-52.571 12.286-118t38-164.286 29.714-116q-18.286-37.143-18.286-96.571 0-47.429 29.714-89.143t75.429-41.714q34.857 0 54.286 23.143t19.429 58.571q0 37.714-25.143 109.143t-25.143 106.857q0 36 25.714 59.714t62.286 23.714q31.429 0 58.286-14.286t44.857-38.857 32-54.286 21.714-63.143 11.429-63.429 3.714-56.857q0-98.857-62.571-154t-163.143-55.143q-114.286 0-190.857 74t-76.571 187.714q0 25.143 7.143 48.571t15.429 37.143 15.429 26 7.143 17.429q0 16-8.571 41.714t-21.143 25.714q-1.143 0-9.714-1.714-29.143-8.571-51.714-32t-34.857-54-18.571-61.714-6.286-60.857z"></path>
</symbol>
<symbol id="uw-symbol-twitter" class="uw-social-symbols" viewBox="0 0 951 1024">
<title>twitter</title>
<path class="path1" d="M925.714 233.143q-38.286 56-92.571 95.429 0.571 8 0.571 24 0 74.286-21.714 148.286t-66 142-105.429 120.286-147.429 83.429-184.571 31.143q-154.857 0-283.429-82.857 20 2.286 44.571 2.286 128.571 0 229.143-78.857-60-1.143-107.429-36.857t-65.143-91.143q18.857 2.857 34.857 2.857 24.571 0 48.571-6.286-64-13.143-106-63.714t-42-117.429v-2.286q38.857 21.714 83.429 23.429-37.714-25.143-60-65.714t-22.286-88q0-50.286 25.143-93.143 69.143 85.143 168.286 136.286t212.286 56.857q-4.571-21.714-4.571-42.286 0-76.571 54-130.571t130.571-54q80 0 134.857 58.286 62.286-12 117.143-44.571-21.143 65.714-81.143 101.714 53.143-5.714 106.286-28.571z"></path>
</symbol>
<symbol id="uw-symbol-youtube" class="uw-social-symbols" viewBox="0 0 878 1024">
<title>youtube</title>
<path class="path1" d="M554.857 710.857v120.571q0 38.286-22.286 38.286-13.143 0-25.714-12.571v-172q12.571-12.571 25.714-12.571 22.286 0 22.286 38.286zM748 711.429v26.286h-51.429v-26.286q0-38.857 25.714-38.857t25.714 38.857zM196 586.857h61.143v-53.714h-178.286v53.714h60v325.143h57.143v-325.143zM360.571 912h50.857v-282.286h-50.857v216q-17.143 24-32.571 24-10.286 0-12-12-0.571-1.714-0.571-20v-208h-50.857v223.429q0 28 4.571 41.714 6.857 21.143 33.143 21.143 27.429 0 58.286-34.857v30.857zM605.714 827.429v-112.571q0-41.714-5.143-56.571-9.714-32-40.571-32-28.571 0-53.143 30.857v-124h-50.857v378.857h50.857v-27.429q25.714 31.429 53.143 31.429 30.857 0 40.571-31.429 5.143-15.429 5.143-57.143zM798.857 821.714v-7.429h-52q0 29.143-1.143 34.857-4 20.571-22.857 20.571-26.286 0-26.286-39.429v-49.714h102.286v-58.857q0-45.143-15.429-66.286-22.286-29.143-60.571-29.143-38.857 0-61.143 29.143-16 21.143-16 66.286v98.857q0 45.143 16.571 66.286 22.286 29.143 61.714 29.143 41.143 0 61.714-30.286 10.286-15.429 12-30.857 1.143-5.143 1.143-33.143zM451.429 300v-120q0-39.429-24.571-39.429t-24.571 39.429v120q0 40 24.571 40t24.571-40zM862.286 729.143q0 133.714-14.857 200-8 33.714-33.143 56.571t-58.286 26.286q-105.143 12-317.143 12t-317.143-12q-33.143-3.429-58.571-26.286t-32.857-56.571q-14.857-64-14.857-200 0-133.714 14.857-200 8-33.714 33.143-56.571t58.857-26.857q104.571-11.429 316.571-11.429t317.143 11.429q33.143 4 58.571 26.857t32.857 56.571q14.857 64 14.857 200zM292 0h58.286l-69.143 228v154.857h-57.143v-154.857q-8-42.286-34.857-121.143-21.143-58.857-37.143-106.857h60.571l40.571 150.286zM503.429 190.286v100q0 46.286-16 67.429-21.143 29.143-60.571 29.143-38.286 0-60-29.143-16-21.714-16-67.429v-100q0-45.714 16-66.857 21.714-29.143 60-29.143 39.429 0 60.571 29.143 16 21.143 16 66.857zM694.857 97.714v285.143h-52v-31.429q-30.286 35.429-58.857 35.429-26.286 0-33.714-21.143-4.571-13.714-4.571-42.857v-225.143h52v209.714q0 18.857 0.571 20 1.714 12.571 12 12.571 15.429 0 32.571-24.571v-217.714h52z"></path>
</symbol>
<symbol id="uw-symbol-facebook" class="uw-social-symbols" viewBox="0 0 602 1024">
<title>facebook</title>
<path class="path1" d="M548 6.857v150.857h-89.714q-49.143 0-66.286 20.571t-17.143 61.714v108h167.429l-22.286 169.143h-145.143v433.714h-174.857v-433.714h-145.714v-169.143h145.714v-124.571q0-106.286 59.429-164.857t158.286-58.571q84 0 130.286 6.857z"></path>
</symbol>
<symbol id="uw-symbol-instagram" class="uw-social-symbols" viewBox="0 0 878 1024">
<title>instagram</title>
<path class="path1" d="M778.286 814.857v-370.286h-77.143q11.429 36 11.429 74.857 0 72-36.571 132.857t-99.429 96.286-137.143 35.429q-112.571 0-192.571-77.429t-80-187.143q0-38.857 11.429-74.857h-80.571v370.286q0 14.857 10 24.857t24.857 10h610.857q14.286 0 24.571-10t10.286-24.857zM616 510.286q0-70.857-51.714-120.857t-124.857-50q-72.571 0-124.286 50t-51.714 120.857 51.714 120.857 124.286 50q73.143 0 124.857-50t51.714-120.857zM778.286 304.571v-94.286q0-16-11.429-27.714t-28-11.714h-99.429q-16.571 0-28 11.714t-11.429 27.714v94.286q0 16.571 11.429 28t28 11.429h99.429q16.571 0 28-11.429t11.429-28zM877.714 185.714v652.571q0 46.286-33.143 79.429t-79.429 33.143h-652.571q-46.286 0-79.429-33.143t-33.143-79.429v-652.571q0-46.286 33.143-79.429t79.429-33.143h652.571q46.286 0 79.429 33.143t33.143 79.429z"></path>
</symbol>
<symbol id="uw-symbol-caret-up" viewBox="0 0 1792 1792">
<title>Collapse</title>
<path d="M1395 1184q0 13-10 23l-50 50q-10 10-23 10t-23-10l-393-393-393 393q-10 10-23 10t-23-10l-50-50q-10-10-10-23t10-23l466-466q10-10 23-10t23 10l466 466q10 10 10 23z"></path>
</symbol>
<symbol id="uw-symbol-caret-down" viewBox="0 0 1792 1792">
<title>Expand</title>
<path d="M1395 736q0 13-10 23l-466 466q-10 10-23 10t-23-10l-466-466q-10-10-10-23t10-23l50-50q10-10 23-10t23 10l393 393 393-393q10-10 23-10t23 10l50 50q10 10 10 23z"></path>
</symbol>
<symbol id="uw-symbol-chevron-right" viewBox="0 0 695 1024">
<title id="svg-next-slide">next slide</title>
<path class="path1" d="M632.571 501.143l-424 424q-10.857 10.857-25.714 10.857t-25.714-10.857l-94.857-94.857q-10.857-10.857-10.857-25.714t10.857-25.714l303.429-303.429-303.429-303.429q-10.857-10.857-10.857-25.714t10.857-25.714l94.857-94.857q10.857-10.857 25.714-10.857t25.714 10.857l424 424q10.857 10.857 10.857 25.714t-10.857 25.714z"></path>
</symbol>
<symbol id="uw-symbol-chevron-left" viewBox="0 0 768 1024">
<title id="svg-previous">previous slide</title>
<path class="path1" d="M669.143 172l-303.429 303.429 303.429 303.429q10.857 10.857 10.857 25.714t-10.857 25.714l-94.857 94.857q-10.857 10.857-25.714 10.857t-25.714-10.857l-424-424q-10.857-10.857-10.857-25.714t10.857-25.714l424-424q10.857-10.857 25.714-10.857t25.714 10.857l94.857 94.857q10.857 10.857 10.857 25.714t-10.857 25.714z"></path>
</symbol>
<symbol id="uw-symbol-crest-footer" viewBox="0 0 200 132.78">
<title id="svg-crest-footer">Footer Crest</title>
<path d="M31.65,93.63c3,1.09,1.75,4.35,1,6.65L28.31,115l-5.4-17.44a8.47,8.47,0,0,1-.58-4.07H16.85v0.12c2.14,1.13,1.36,3.75.62,6.2l-4.55,15.31L7.14,96.41a7.23,7.23,0,0,1-.47-2.9H1v0.12c1.94,1.37,2.53,4,3.23,6.2l4.58,14.86c1.28,4.15,1.63,3.87,5.16,6.53L20,100.88l4.27,13.86c1.29,4.15,1.56,3.95,5.13,6.49l8.19-27.71h-6v0.12Z" transform="translate(-1 -0.61)"/><path d="M38.95,93.63c2,0.77,1.71,3.71,1.71,5.56v15.18c0,1.81.23,4.8-1.71,5.52V120h7.38v-0.12c-1.94-.77-1.71-3.71-1.71-5.52V99.19c0-1.81-.23-4.79,1.71-5.56V93.51H38.95v0.12Z" transform="translate(-1 -0.61)"/><path d="M53.12,99.43c0-2.78,2.8-3.67,5-3.67a8.68,8.68,0,0,1,6.1,2.54V93.75a18.9,18.9,0,0,0-5.79-.89c-4.74,0-9.75,1.94-9.75,7,0,8.54,13.36,7.41,13.36,13.7,0,2.82-3.34,4.19-5.55,4.19A13.17,13.17,0,0,1,48,114.41l1.13,5a19.44,19.44,0,0,0,7,1.21c6.06,0,10.41-4,10.41-8.34C66.49,104.87,53.12,104.95,53.12,99.43Z" transform="translate(-1 -0.61)"/><path d="M82.23,117.32c-6,0-9.87-5.28-9.87-11.2s3.73-9.91,9.09-9.91a13.15,13.15,0,0,1,7.19,2.3V93.87a30,30,0,0,0-7.07-1c-8,0-13.64,5.52-13.64,13.86,0,8.62,5.67,13.94,14.84,13.94a13.31,13.31,0,0,0,5.86-1.21l2-4.67H90.5A16.7,16.7,0,0,1,82.23,117.32Z" transform="translate(-1 -0.61)"/><path d="M104.63,92.83a14,14,0,0,0-14.57,13.85,13.83,13.83,0,0,0,14.18,14,14.09,14.09,0,0,0,14.29-14.18A13.63,13.63,0,0,0,104.63,92.83Zm-0.19,24.93c-6.1,0-9.95-5.8-9.95-11.44,0-6.08,3.85-10.59,9.87-10.59s9.75,5.68,9.75,11.56S110.34,117.75,104.44,117.75Z" transform="translate(-1 -0.61)"/><path d="M138.49,93.63c2.06,1.21,2,2.82,2,5.08V114L126.29,95.36l-0.55-.81a2.48,2.48,0,0,1-.58-1v0H119.5v0.12c2,1.21,2,2.82,2,5.08v16.07c0,2.25,0,3.86-2.06,5.11V120h6.88v-0.12c-2.06-1.25-2-2.86-2-5.11V99.19l13.32,17.52c1.71,2.3,2.91,3.63,5.67,4.6V98.7c0-2.25,0-3.87,2-5.08V93.51h-6.84v0.12Z" transform="translate(-1 -0.61)"/><path d="M151,99.43c0-2.78,2.8-3.67,5-3.67a8.68,8.68,0,0,1,6.1,2.54V93.75a18.86,18.86,0,0,0-5.79-.89c-4.73,0-9.75,1.94-9.75,7,0,8.54,13.36,7.41,13.36,13.7,0,2.82-3.34,4.19-5.56,4.19a13.18,13.18,0,0,1-8.51-3.34l1.13,5a19.46,19.46,0,0,0,7,1.21c6.06,0,10.41-4,10.41-8.34C164.37,104.87,151,104.95,151,99.43Z" transform="translate(-1 -0.61)"/><path d="M165.84,93.63c2,0.77,1.71,3.71,1.71,5.56v15.18c0,1.81.24,4.8-1.71,5.52V120h7.38v-0.12c-1.94-.77-1.71-3.71-1.71-5.52V99.19c0-1.81-.24-4.79,1.71-5.56V93.51h-7.38v0.12Z" transform="translate(-1 -0.61)"/><path d="M194.16,93.51v0.12c2.06,1.21,2,2.82,2,5.08V114L182,95.36l-0.55-.81a2.6,2.6,0,0,1-.58-1v0h-5.67v0.12c2,1.21,2,2.82,2,5.08v16.07c0,2.25,0,3.86-2.06,5.11V120H182v-0.12c-2.06-1.25-2-2.86-2-5.11V99.19l13.32,17.52c1.71,2.3,2.92,3.63,5.67,4.6V98.7c0-2.25,0-3.87,2-5.08V93.51h-6.84Z" transform="translate(-1 -0.61)"/><path d="M12.72,126.16v4.62a2.75,2.75,0,0,1-.34,1.38,2.27,2.27,0,0,1-1,.91,3.4,3.4,0,0,1-1.54.32,2.87,2.87,0,0,1-2.07-.7,2.55,2.55,0,0,1-.74-1.93v-4.6H8.24v4.52a1.81,1.81,0,0,0,.41,1.3,1.69,1.69,0,0,0,1.26.42,1.5,1.5,0,0,0,1.65-1.73v-4.51h1.17Z" transform="translate(-1 -0.61)"/><path d="M20.74,133.29H19.31l-3.51-5.69h0l0,0.32q0.07,0.91.07,1.66v3.71H14.79v-7.14h1.42l3.5,5.66h0c0-.08,0-0.35,0-0.82s0-.84,0-1.1v-3.74h1.07v7.14Z" transform="translate(-1 -0.61)"/><path d="M23,133.29v-7.14h1.17v7.14H23Z" transform="translate(-1 -0.61)"/><path d="M30.42,126.16h1.21l-2.5,7.14H27.9l-2.49-7.14h1.2l1.49,4.44c0.08,0.21.16,0.48,0.25,0.82s0.14,0.58.17,0.75c0-.25.11-0.53,0.2-0.86s0.16-.57.21-0.72Z" transform="translate(-1 -0.61)"/><path d="M37,133.29h-4v-7.14h4v1H34.08v1.94h2.69v1H34.08v2.24H37v1Z" transform="translate(-1 -0.61)"/><path d="M40,130.44v2.85H38.84v-7.14h2a3.32,3.32,0,0,1,2,.52,1.86,1.86,0,0,1,.66,1.56,2,2,0,0,1-1.39,1.9l2,3.16H42.86l-1.71-2.85H40Zm0-1h0.81a1.85,1.85,0,0,0,1.18-.3,1.1,1.1,0,0,0,.37-0.9,1,1,0,0,0-.4-0.87,2.17,2.17,0,0,0-1.19-.26H40v2.33Z" transform="translate(-1 -0.61)"/><path d="M49.68,131.36a1.8,1.8,0,0,1-.69,1.49,3,3,0,0,1-1.9.54,4.53,4.53,0,0,1-2-.38v-1.1a5.34,5.34,0,0,0,1,.36,4.39,4.39,0,0,0,1,.13,1.62,1.62,0,0,0,1-.26,0.86,0.86,0,0,0,.33-0.71,0.89,0.89,0,0,0-.3-0.68A4.57,4.57,0,0,0,47,130.1a3.31,3.31,0,0,1-1.38-.9,1.91,1.91,0,0,1-.4-1.22,1.71,1.71,0,0,1,.63-1.41,2.63,2.63,0,0,1,1.7-.51,5,5,0,0,1,2,.45l-0.37,1a4.47,4.47,0,0,0-1.7-.4,1.31,1.31,0,0,0-.86.25,0.81,0.81,0,0,0-.29.65,0.92,0.92,0,0,0,.12.48,1.2,1.2,0,0,0,.39.37,6.52,6.52,0,0,0,1,.46,5.31,5.31,0,0,1,1.15.61,1.8,1.8,0,0,1,.54.64A1.93,1.93,0,0,1,49.68,131.36Z" transform="translate(-1 -0.61)"/><path d="M51.41,133.29v-7.14h1.17v7.14H51.41Z" transform="translate(-1 -0.61)"/><path d="M57.26,133.29H56.1v-6.14H54v-1h5.37v1h-2.1v6.14Z" transform="translate(-1 -0.61)"/><path d="M62.81,129.41l1.69-3.26h1.27l-2.38,4.37v2.77H62.22v-2.73l-2.37-4.41h1.27Z" transform="translate(-1 -0.61)"/><path d="M76.33,129.71a3.9,3.9,0,0,1-.87,2.71,3.66,3.66,0,0,1-5,0,3.93,3.93,0,0,1-.87-2.73,3.86,3.86,0,0,1,.87-2.71A3.21,3.21,0,0,1,73,126a3.14,3.14,0,0,1,2.46,1A3.9,3.9,0,0,1,76.33,129.71Zm-5.45,0a3.19,3.19,0,0,0,.53,2,2.16,2.16,0,0,0,3.15,0,4.05,4.05,0,0,0,0-4A1.86,1.86,0,0,0,73,127a1.9,1.9,0,0,0-1.58.68A3.18,3.18,0,0,0,70.88,129.71Z" transform="translate(-1 -0.61)"/><path d="M79.36,133.29H78.2v-7.14h4v1H79.36v2.23h2.69v1H79.36v2.93Z" transform="translate(-1 -0.61)"/><path d="M93.39,133.29H92.12L90.91,129c-0.05-.19-0.12-0.45-0.2-0.8s-0.12-.59-0.14-0.73q0,0.31-.16.81c-0.07.33-.13,0.58-0.18,0.74L89,133.29H87.78l-0.92-3.57-0.94-3.56h1.19l1,4.16q0.24,1,.34,1.77c0-.28.09-0.59,0.16-0.93s0.14-.62.2-0.83L90,126.16h1.16l1.19,4.19a15.38,15.38,0,0,1,.36,1.74,12.74,12.74,0,0,1,.35-1.78l1-4.15h1.18Z" transform="translate(-1 -0.61)"/><path d="M96.6,133.29v-7.14h1.17v7.14H96.6Z" transform="translate(-1 -0.61)"/><path d="M104.11,131.36a1.8,1.8,0,0,1-.69,1.49,3,3,0,0,1-1.9.54,4.53,4.53,0,0,1-2-.38v-1.1a5.4,5.4,0,0,0,1,.36,4.42,4.42,0,0,0,1,.13,1.63,1.63,0,0,0,1-.26,0.86,0.86,0,0,0,.33-0.71,0.89,0.89,0,0,0-.3-0.68,4.59,4.59,0,0,0-1.25-.66,3.29,3.29,0,0,1-1.38-.9,1.91,1.91,0,0,1-.4-1.22,1.71,1.71,0,0,1,.63-1.41,2.63,2.63,0,0,1,1.7-.51,5,5,0,0,1,2,.45l-0.37,1a4.47,4.47,0,0,0-1.7-.4,1.31,1.31,0,0,0-.86.25,0.81,0.81,0,0,0-.29.65,0.92,0.92,0,0,0,.12.48,1.2,1.2,0,0,0,.39.37,6.43,6.43,0,0,0,1,.46,5.31,5.31,0,0,1,1.15.61,1.81,1.81,0,0,1,.54.64A1.93,1.93,0,0,1,104.11,131.36Z" transform="translate(-1 -0.61)"/><path d="M108.87,127.05a1.92,1.92,0,0,0-1.58.71,3.75,3.75,0,0,0,0,4,2,2,0,0,0,1.61.67,4.26,4.26,0,0,0,.88-0.09c0.28-.06.58-0.14,0.88-0.23v1a5.34,5.34,0,0,1-1.9.32,3,3,0,0,1-2.41-.95,4,4,0,0,1-.84-2.72,4.4,4.4,0,0,1,.41-1.95,2.92,2.92,0,0,1,1.18-1.28,3.58,3.58,0,0,1,1.81-.44,4.5,4.5,0,0,1,2,.46l-0.42,1a6.37,6.37,0,0,0-.77-0.3A2.75,2.75,0,0,0,108.87,127.05Z" transform="translate(-1 -0.61)"/><path d="M118.85,129.71a3.9,3.9,0,0,1-.87,2.71,3.15,3.15,0,0,1-2.47,1,3.18,3.18,0,0,1-2.48-1,3.94,3.94,0,0,1-.87-2.73A3.86,3.86,0,0,1,113,127a3.21,3.21,0,0,1,2.49-.95,3.15,3.15,0,0,1,2.46,1A3.91,3.91,0,0,1,118.85,129.71Zm-5.45,0a3.21,3.21,0,0,0,.53,2,2.16,2.16,0,0,0,3.15,0,4,4,0,0,0,0-4,1.86,1.86,0,0,0-1.56-.68,1.9,1.9,0,0,0-1.59.68A3.18,3.18,0,0,0,113.4,129.71Z" transform="translate(-1 -0.61)"/><path d="M126.67,133.29h-1.43l-3.51-5.69h0l0,0.32q0.07,0.91.07,1.66v3.71h-1.06v-7.14h1.42l3.5,5.66h0c0-.08,0-0.35,0-0.82s0-.84,0-1.1v-3.74h1.07v7.14Z" transform="translate(-1 -0.61)"/><path d="M133,131.36a1.8,1.8,0,0,1-.69,1.49,3,3,0,0,1-1.9.54,4.52,4.52,0,0,1-2-.38v-1.1a5.31,5.31,0,0,0,1,.36,4.39,4.39,0,0,0,1,.13,1.62,1.62,0,0,0,1-.26,0.86,0.86,0,0,0,.33-0.71,0.88,0.88,0,0,0-.3-0.68,4.53,4.53,0,0,0-1.25-.66,3.31,3.31,0,0,1-1.38-.9,1.92,1.92,0,0,1-.4-1.22,1.71,1.71,0,0,1,.63-1.41,2.64,2.64,0,0,1,1.71-.51,5,5,0,0,1,2,.45l-0.37,1a4.47,4.47,0,0,0-1.7-.4,1.3,1.3,0,0,0-.86.25,0.81,0.81,0,0,0-.29.65,0.92,0.92,0,0,0,.12.48,1.22,1.22,0,0,0,.38.37,6.63,6.63,0,0,0,1,.46,5.26,5.26,0,0,1,1.15.61,1.79,1.79,0,0,1,.54.64A1.9,1.9,0,0,1,133,131.36Z" transform="translate(-1 -0.61)"/><path d="M134.73,133.29v-7.14h1.17v7.14h-1.17Z" transform="translate(-1 -0.61)"/><path d="M144.07,133.29h-1.43l-3.51-5.69h0l0,0.32c0,0.61.07,1.16,0.07,1.66v3.71h-1.06v-7.14h1.42l3.5,5.66h0c0-.08,0-0.35,0-0.82s0-.84,0-1.1v-3.74h1.07v7.14Z" transform="translate(-1 -0.61)"/><path d="M145.75,131.07v-0.93h4.2v0.93h-4.2Z" transform="translate(-1 -0.61)"/><path d="M154.72,133.29l-2.07-6h0q0.08,1.33.08,2.49v3.47h-1.06v-7.14h1.64l2,5.68h0l2-5.68H159v7.14h-1.12v-3.53q0-.53,0-1.39c0-.57,0-0.92,0-1h0l-2.14,6h-1Z" transform="translate(-1 -0.61)"/><path d="M165.63,133.29l-0.71-2h-2.73l-0.7,2h-1.23l2.67-7.17h1.27l2.67,7.17h-1.24Zm-1-3-0.67-1.94c0-.13-0.12-0.33-0.2-0.62s-0.14-.49-0.18-0.62a11.19,11.19,0,0,1-.38,1.31l-0.64,1.86h2.08Z" transform="translate(-1 -0.61)"/><path d="M174,129.66a3.56,3.56,0,0,1-1,2.7,3.94,3.94,0,0,1-2.83.94h-2v-7.14h2.21a3.65,3.65,0,0,1,2.65.92A3.43,3.43,0,0,1,174,129.66Zm-1.23,0q0-2.56-2.4-2.56h-1v5.18h0.83A2.3,2.3,0,0,0,172.73,129.7Z" transform="translate(-1 -0.61)"/><path d="M175.83,133.29v-7.14H177v7.14h-1.17Z" transform="translate(-1 -0.61)"/><path d="M183.34,131.36a1.8,1.8,0,0,1-.69,1.49,3,3,0,0,1-1.9.54,4.52,4.52,0,0,1-2-.38v-1.1a5.31,5.31,0,0,0,1,.36,4.39,4.39,0,0,0,1,.13,1.62,1.62,0,0,0,1-.26,0.86,0.86,0,0,0,.33-0.71,0.88,0.88,0,0,0-.3-0.68,4.53,4.53,0,0,0-1.25-.66,3.31,3.31,0,0,1-1.38-.9,1.92,1.92,0,0,1-.4-1.22,1.71,1.71,0,0,1,.63-1.41,2.64,2.64,0,0,1,1.71-.51,5,5,0,0,1,2,.45l-0.37,1a4.47,4.47,0,0,0-1.7-.4,1.3,1.3,0,0,0-.86.25,0.81,0.81,0,0,0-.29.65,0.92,0.92,0,0,0,.12.48,1.22,1.22,0,0,0,.38.37,6.63,6.63,0,0,0,1,.46,5.26,5.26,0,0,1,1.15.61,1.79,1.79,0,0,1,.54.64A1.9,1.9,0,0,1,183.34,131.36Z" transform="translate(-1 -0.61)"/><path d="M191.4,129.71a3.91,3.91,0,0,1-.87,2.71,3.66,3.66,0,0,1-5,0,3.93,3.93,0,0,1-.87-2.73,3.87,3.87,0,0,1,.87-2.71,3.21,3.21,0,0,1,2.49-.95,3.14,3.14,0,0,1,2.46,1A3.9,3.9,0,0,1,191.4,129.71Zm-5.45,0a3.19,3.19,0,0,0,.53,2,2.16,2.16,0,0,0,3.15,0,4.05,4.05,0,0,0,0-4,1.86,1.86,0,0,0-1.56-.68,1.89,1.89,0,0,0-1.58.68A3.16,3.16,0,0,0,185.95,129.71Z" transform="translate(-1 -0.61)"/><path d="M199.22,133.29h-1.43l-3.51-5.69h0l0,0.32q0.07,0.91.07,1.66v3.71h-1.06v-7.14h1.42l3.5,5.66h0c0-.08,0-0.35,0-0.82s0-.84,0-1.1v-3.74h1.07v7.14Z" transform="translate(-1 -0.61)"/><path d="M131.41,31.93a49.5,49.5,0,0,0-.86-5.5,39.81,39.81,0,0,0-1.39-4.93,31.28,31.28,0,0,0-2.23-4.93,22.63,22.63,0,0,0-3-4.1,14.94,14.94,0,0,0-11-5.23h-0.09a5.77,5.77,0,0,0-4.16-2.91,4.93,4.93,0,0,0-9.56,0A5.77,5.77,0,0,0,95,7.25H95a14.94,14.94,0,0,0-11,5.23,22.63,22.63,0,0,0-3,4.1,31.28,31.28,0,0,0-2.23,4.93,39.81,39.81,0,0,0-1.39,4.93,49.49,49.49,0,0,0-.86,5.5c-2.3,22.62,7.87,50.42,26.16,54.68A3.17,3.17,0,0,0,104,87.89a3.17,3.17,0,0,0,1.27-1.28C123.54,82.35,133.71,54.55,131.41,31.93ZM104,1.48a3.9,3.9,0,0,1,3.93,2.76,4.86,4.86,0,0,0-3.86,2.47,0.17,0.17,0,0,1-.07.09,0.15,0.15,0,0,1-.07-0.09,4.86,4.86,0,0,0-3.86-2.47A3.9,3.9,0,0,1,104,1.48Zm-1.86,4.29a3.51,3.51,0,0,1,1.59,2.11,0.29,0.29,0,1,0,.53,0,3.51,3.51,0,0,1,1.59-2.11,4.19,4.19,0,0,1,6,1.58,13.38,13.38,0,0,0-1.67.42,6.6,6.6,0,0,0-2.38,1.32,9.4,9.4,0,0,0-3,6.1c-0.67,7.31,7.72,6.16,8.14,6.13,1.08,0,1.9-1.71,1.9-4s-0.84-4-1.9-4c-0.65,0-1.77.52-1.88,2.55-0.07,1.42.62,3.32,1.52,3.44,0.47,0.06.89-.76,1-1.6s0.06-1.87-.59-2a0.38,0.38,0,0,0-.46.28,3.83,3.83,0,0,1,.39,1.34c0,1.25-1.28.63-1.12-1.36,0.15-1.76,1.05-1.65,1.09-1.65,0.5,0,1.26,1,1.26,3,0,1.75-.84,3.63-2.46,2.65-1.36-1-1.89-3.28-1.52-5,0.17-.81.87-3,3.13-3,3.26,0,6.3,1.71,8.72,4.9-0.27.85-1.95,4.1-7.28,7.21l-0.29.15a11,11,0,0,0-4.93-1,27.08,27.08,0,0,0-4.64.74,2.89,2.89,0,0,1-1.84,0,27.08,27.08,0,0,0-4.64-.74,11,11,0,0,0-4.93,1L93.2,24c-5.34-3.11-7-6.36-7.28-7.21,2.42-3.19,5.46-4.9,8.72-4.9,2.26,0,3,2.21,3.13,3,0.38,1.77-.16,4.05-1.52,5-1.61,1-2.46-.9-2.46-2.65,0-2,.76-3,1.26-3,0,0,.94-0.11,1.09,1.65C96.31,18,95,18.6,95,17.35A3.83,3.83,0,0,1,95.41,16a0.38,0.38,0,0,0-.46-0.28c-0.65.16-.71,1.3-0.59,2s0.56,1.66,1,1.6c0.9-.12,1.6-2,1.52-3.44-0.1-2-1.23-2.55-1.88-2.55-1.06,0-1.9,1.71-1.9,4s0.82,4,1.9,4c0.42,0,8.81,1.18,8.14-6.13a9.4,9.4,0,0,0-3-6.1,6.6,6.6,0,0,0-2.38-1.32,13.38,13.38,0,0,0-1.67-.42A4.19,4.19,0,0,1,102.12,5.77ZM86.34,35.9a15.81,15.81,0,0,1-5.8-1.67c0.44-7.31,2.29-13.05,5-16.87,0.48,1.24,2.57,4.35,7.39,7.18C88.82,27,87,32.1,86.34,35.9Zm7.08-10.48a9.35,9.35,0,0,1,4.37-1.21c2.74-.18,4.79.87,6.16,0.91H104c1.37,0,3.4-1.09,6.14-.91a9.41,9.41,0,0,1,4.39,1.21c5.58,3.56,6.37,11.77,6.48,14.46a43.53,43.53,0,0,1-3.54,19c-3.86,8.51-8.53,14.53-13.14,16.57L104,75.6l-0.37-.16c-4.61-2-9.27-8.06-13.14-16.57a43.52,43.52,0,0,1-3.54-19C87,37.19,87.83,29,93.42,25.42Zm-7.16,11a32.49,32.49,0,0,0-.32,3.31A44.42,44.42,0,0,0,88,55a49.48,49.48,0,0,0,4.13,9.32A11.48,11.48,0,0,1,87,66.64a66.66,66.66,0,0,1-6.47-31.82A16.13,16.13,0,0,0,86.26,36.43Zm6.14,28.35c3.08,5.3,6.12,8.46,8.45,10.14a11.54,11.54,0,0,1-3.54,4.36c-4-2.7-7.4-7-10.07-12.13A11.81,11.81,0,0,0,92.39,64.78Zm8.91,10.46A12.19,12.19,0,0,0,104,76.71a12.2,12.2,0,0,0,2.67-1.47,12,12,0,0,0,3.53,4.34,18.69,18.69,0,0,1-3.58,1.78s0-.09,0-0.13c-0.26-1.32-2-1.59-2.61-1.59s-2.35.27-2.61,1.59c0,0,0,.09,0,0.13a18.69,18.69,0,0,1-3.58-1.78A12,12,0,0,0,101.31,75.24Zm5.81-.32c2.33-1.67,5.37-4.83,8.45-10.14a11.81,11.81,0,0,0,5.16,2.36c-2.67,5.16-6.06,9.43-10.07,12.13A11.54,11.54,0,0,1,107.12,74.91Zm8.72-10.61A49.48,49.48,0,0,0,120,55a44.42,44.42,0,0,0,2-15.25,32.48,32.48,0,0,0-.32-3.31,16.13,16.13,0,0,0,5.75-1.61A66.66,66.66,0,0,1,121,66.64,11.48,11.48,0,0,1,115.84,64.3Zm5.78-28.4c-0.62-3.8-2.5-8.8-6.58-11.36,4.82-2.83,6.92-5.94,7.39-7.18,2.69,3.82,4.55,9.56,5,16.87A15.81,15.81,0,0,1,121.62,35.9ZM101,85a23.29,23.29,0,0,1-5.87-2.93,27.5,27.5,0,0,1-3.25-2.62A31.1,31.1,0,0,1,89.53,77q-0.76-.88-1.46-1.81a47.49,47.49,0,0,1-5.58-9.69,63.91,63.91,0,0,1-3.42-10.2,70.46,70.46,0,0,1-1.79-10.85,64.57,64.57,0,0,1-.07-10.84c0.16-1.93.39-3.86,0.74-5.77a39.32,39.32,0,0,1,1.43-5.61,31,31,0,0,1,2.1-4.86,20.93,20.93,0,0,1,3.15-4.44,16.19,16.19,0,0,1,4-3.1A13.93,13.93,0,0,1,90.53,9q0.51-.18,1-0.32a4.35,4.35,0,0,1,1-.24,14,14,0,0,1,2.56-.23,7.58,7.58,0,0,1,3.88,1,8,8,0,0,1,3.34,6c0.39,4.52-4.21,5.23-5.11,5.22-0.14,0-.21-0.13.24-0.59a6.53,6.53,0,0,0,1-5.1c-0.44-2.07-1.9-3.69-4-3.69A11.16,11.16,0,0,0,86.41,15a22.78,22.78,0,0,0-4.47,7.87,42.69,42.69,0,0,0-2.2,11.38A62.43,62.43,0,0,0,80,44.88a68.71,68.71,0,0,0,1.95,10.59,60.82,60.82,0,0,0,3.53,9.85,43.36,43.36,0,0,0,5.48,9,25.89,25.89,0,0,0,8.13,6.87,18.15,18.15,0,0,0,2.21,1,6.71,6.71,0,0,0,.67,3.1A6.63,6.63,0,0,1,101,85Zm3.29,1.55a0.34,0.34,0,0,1-.62,0,6.49,6.49,0,0,1-1.51-5.17c0.12-.64,1.2-0.93,1.82-0.94s1.7,0.3,1.82.94A6.49,6.49,0,0,1,104.29,86.55Zm26.38-42.11a70.46,70.46,0,0,1-1.79,10.85,63.9,63.9,0,0,1-3.42,10.2,47.49,47.49,0,0,1-5.58,9.69q-0.7.93-1.46,1.81a31.1,31.1,0,0,1-2.35,2.47,27.5,27.5,0,0,1-3.25,2.62A23.29,23.29,0,0,1,107,85a6.63,6.63,0,0,1-.93.28,6.71,6.71,0,0,0,.67-3.1,18.15,18.15,0,0,0,2.21-1A25.89,25.89,0,0,0,117,74.35a43.36,43.36,0,0,0,5.48-9A60.82,60.82,0,0,0,126,55.47,68.71,68.71,0,0,0,128,44.88a62.43,62.43,0,0,0,.23-10.64A42.69,42.69,0,0,0,126,22.86,22.78,22.78,0,0,0,121.55,15a11.16,11.16,0,0,0-8.12-3.89c-2.12,0-3.58,1.62-4,3.69a6.53,6.53,0,0,0,1,5.1c0.45,0.46.38,0.59,0.24,0.59-0.9,0-5.51-.71-5.11-5.22a8,8,0,0,1,3.34-6,7.58,7.58,0,0,1,3.88-1,14,14,0,0,1,2.56.23,4.35,4.35,0,0,1,1,.24q0.52,0.14,1,.32a13.93,13.93,0,0,1,1.93.87,16.19,16.19,0,0,1,4,3.1,20.93,20.93,0,0,1,3.15,4.44,31,31,0,0,1,2.1,4.86A39.33,39.33,0,0,1,130,27.84c0.35,1.91.58,3.84,0.74,5.77A64.57,64.57,0,0,1,130.68,44.45Z" transform="translate(-1 -0.61)"/><path d="M112.28,33.43v1.86l0.38-.06h0.18a1.17,1.17,0,0,1,.82.28,1.27,1.27,0,0,1,.21,1.11s-3.74,16.19-4.45,19.27c-0.82-3.9-5.26-25.18-5.26-25.18l0-.09h-0.88v0.1L99.38,55.57,95,36.62a2.7,2.7,0,0,1,0-.28,1.27,1.27,0,0,1,.31-1A1,1,0,0,1,96,35.17l0.37,0v-1.8H90.11v1.76l0.28,0a1.16,1.16,0,0,1,.95.83l7.61,32.67,0,0.09h1.1v-0.1l3.56-23.3,4.53,23.31,0,0.09h1L116.41,36a1,1,0,0,1,1-.75h0.07l0.36,0V33.43h-5.58Z" transform="translate(-1 -0.61)"/>
</symbol>
</defs>
</svg>
</body>
</html>