QuoTHiC (Quantification of Transcription Heterogeneity in Cells) provides functions to calculate transcription heterogeneity indices like Silhouette score and Shannon entropy for single-cell RNA-seq data using Seurat objects.
# Install from GitHub
install.packages("devtools")
devtools::install_github("CompEpigen/quothic")Please check the tutorial at https://compepigen.github.io/quothic/