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How to handle the gaps in the maf comparison block? #1596

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helloworldABCD1234 opened this issue Jan 24, 2025 · 1 comment
Open

How to handle the gaps in the maf comparison block? #1596

helloworldABCD1234 opened this issue Jan 24, 2025 · 1 comment

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@helloworldABCD1234
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How to handle the gaps in the maf comparison block, such as
a
s chr1 ttgt-------TATAGCG
s chr2 TTgt------TAGTGAT
s chr3 tTgt------TAGTGAT
Can I delete the gap? Will this damage the integrity of the maf file?

@glennhickey
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As long as you only delete columns entirely of - characters, you won't affect the MAFs integrity (but there should be no such columns in the output). If you delete non-gap characters, then the coordinates become invalid. If you want a MAF with no gaps, you can try --maximumGapLength 0 or --raw to turn off block merging (you get get many more blocks though).

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