diff --git a/src/JsonSchema/SchemaFactory.php b/src/JsonSchema/SchemaFactory.php
index 097eaddd4b8..ea25a99c983 100644
--- a/src/JsonSchema/SchemaFactory.php
+++ b/src/JsonSchema/SchemaFactory.php
@@ -74,6 +74,14 @@ public function buildSchema(string $className, string $format = 'json', string $
             return $schema;
         }
 
+        if ('input' === $type && !($operation?->canDeserialize() ?? true)) {
+            return $schema;
+        }
+
+        if ('output' === $type && !($operation?->canSerialize() ?? true)) {
+            return $schema;
+        }
+
         $validationGroups = $operation ? $this->getValidationGroups($operation) : [];
         $version = $schema->getVersion();
         $definitionName = $this->definitionNameFactory->create($className, $format, $inputOrOutputClass, $operation, $serializerContext);
diff --git a/tests/Fixtures/TestBundle/ApiResource/Issue6276/SerializeResource.php b/tests/Fixtures/TestBundle/ApiResource/Issue6276/SerializeResource.php
new file mode 100644
index 00000000000..3613a566257
--- /dev/null
+++ b/tests/Fixtures/TestBundle/ApiResource/Issue6276/SerializeResource.php
@@ -0,0 +1,21 @@
+<?php
+
+/*
+ * This file is part of the API Platform project.
+ *
+ * (c) Kévin Dunglas <dunglas@gmail.com>
+ *
+ * For the full copyright and license information, please view the LICENSE
+ * file that was distributed with this source code.
+ */
+
+declare(strict_types=1);
+
+namespace ApiPlatform\Tests\Fixtures\TestBundle\ApiResource\Issue6276;
+
+use ApiPlatform\Metadata\Delete;
+
+#[Delete(deserialize: false, serialize: false)]
+final class SerializeResource
+{
+}