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EPL-Signalling-Model

Combinatorial inhibition of signaling pathways to reveal emergent properties of the mESC-EPL cell transition

This repository contains the input data and code for statistical analysis and visalization for Hannah J. Glover, Holly Holliday, Rachel A. Shparberg, David Winkler, Margot Day, Michael B. Morris; Signalling pathway crosstalk stimulated by L-proline drives mouse embryonic stem cells to primitive-ectoderm-like cells. Development 15 October 2023; 150 (20): dev201704. doi: https://doi.org/10.1242/dev.201704