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I am currently facing a similar issue to the one you described regarding the missing contig definitions in the VCF file header. I have attempted to follow the usual steps, but the problem persists, and I keep encountering warnings and errors related to undefined contigs.
I came across your solution on this matter and was wondering if you could kindly share the detailed steps you took to resolve this issue. Your expertise and guidance would be immensely helpful to me in overcoming this challenge.
The error log file as:
[E::bgzf_uncompress] inflate failed: invalid distance too far back
[E::bgzf_read_block] inflate_block error -1
Number of samples in line and header disagrees at chr2:131765544
2023-12-13 10:11:49,962 ERROR Command 'vcfcheck /lustre/home/acct-medfzx/medfzx-lkw/project/CAH/data/database/pangenome/graph/GRCH38/benchmark/HG002_GRCh38_1_22_v4.2.1_benchmark.vcf.gz --check-bcf-errors 1' returned non-zero exit status 1
2023-12-13 10:11:49,962 ERROR Traceback (most recent call last):
2023-12-13 10:11:49,963 ERROR File "/opt/hap.py/bin/hap.py", line 529, in
2023-12-13 10:11:49,963 ERROR main()
2023-12-13 10:11:49,963 ERROR File "/opt/hap.py/bin/hap.py", line 309, in main
2023-12-13 10:11:49,964 ERROR convert_gvcf_to_vcf=args.convert_gvcf_truth)
2023-12-13 10:11:49,964 ERROR File "/opt/hap.py/bin/pre.py", line 125, in preprocess
2023-12-13 10:11:49,964 ERROR mf = subprocess.check_output("vcfcheck %s --check-bcf-errors 1" % pipes.quote(vcf_input), shell=True)
2023-12-13 10:11:49,964 ERROR File "/usr/lib/python2.7/subprocess.py", line 223, in check_output
2023-12-13 10:11:49,967 ERROR raise CalledProcessError(retcode, cmd, output=output)
2023-12-13 10:11:49,967 ERROR CalledProcessError: Command 'vcfcheck /lustre/home/acct-medfzx/medfzx-lkw/project/CAH/data/database/pangenome/graph/GRCH38/benchmark/HG002_GRCh38_1_22_v4.2.1_benchmark.vcf.gz --check-bcf-errors 1' returned non-zero exit status 1
what can i do to solve it.
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