diff --git a/Modules/Core/Transform/include/itkMatrixOffsetTransformBase.hxx b/Modules/Core/Transform/include/itkMatrixOffsetTransformBase.hxx
index 9792b78b1eb..e4cc6c31f4d 100644
--- a/Modules/Core/Transform/include/itkMatrixOffsetTransformBase.hxx
+++ b/Modules/Core/Transform/include/itkMatrixOffsetTransformBase.hxx
@@ -48,6 +48,8 @@ MatrixOffsetTransformBase<TParametersValueType, VInputDimension, VOutputDimensio
   m_MatrixMTime.Modified();
   std::copy_n(offset.begin(), VOutputDimension, m_Translation.begin());
   this->ComputeMatrixParameters();
+  this->m_FixedParameters.SetSize(VInputDimension);
+  this->m_FixedParameters.Fill(0.0);
 }
 
 template <typename TParametersValueType, unsigned int VInputDimension, unsigned int VOutputDimension>