W5.md

Hidden Markov Models HMMs

extension of Markov chain Fair Bet Casino Example Head or Tail - observed Fair or B - path (known - in HMM this is unknown)

pi - path sequence x - emission sequence -

What happen if we don't know the path each possible path that will generate the sequence, the highest possibility learn the possibility

recursion for estimating probability calculate the transigiven data

p(x, M) - decode

model M, sequence x, P(x|M) Estimate transition probabilities a model and new data - find the hidden state sequence

Hommer Pfam EBI InterPro Training online Pfam 1