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@@ -9,12 +9,14 @@ AlphaMissense allows you to identify regions in your amino acid chain that are c
1. It generates a plot similar to [Figure 3D](https://www.science.org/doi/10.1126/science.adg7492#F3) of the [AlphaMissense paper](https://www.science.org/doi/10.1126/science.adg7492)
- ![Alt text](resources/img/3d.png)
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2. It creates a modified PDB file where the temperature factor is replaced by the pathogencity predicted by AlphaMissense that allows you to visualize the effect with Chimerax, like [Figure 3E](https://www.science.org/doi/10.1126/science.adg7492#F3) of the paper:
- ![Alt text](resources/img/3e.jpeg)
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It does so by replacing the bfactor in the PDB.
## How to install