diff --git a/README.md b/README.md index 6af91ef..5109d2f 100644 --- a/README.md +++ b/README.md @@ -9,12 +9,14 @@ AlphaMissense allows you to identify regions in your amino acid chain that are c 1. It generates a plot similar to [Figure 3D](https://www.science.org/doi/10.1126/science.adg7492#F3) of the [AlphaMissense paper](https://www.science.org/doi/10.1126/science.adg7492) - ![Alt text](resources/img/3d.png) + + + 2. It creates a modified PDB file where the temperature factor is replaced by the pathogencity predicted by AlphaMissense that allows you to visualize the effect with Chimerax, like [Figure 3E](https://www.science.org/doi/10.1126/science.adg7492#F3) of the paper: - ![Alt text](resources/img/3e.jpeg) - + + It does so by replacing the bfactor in the PDB. ## How to install