diff --git a/CHANGELOG.md b/CHANGELOG.md
index 97c45de80..53c40b4ae 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -18,6 +18,7 @@
 - Fix custom colors being not being updated when rendering meshes with static topology in OpenGL ([GH-343](https://github.com/NVIDIA/warp/issues/343)).
 - Fix `wp.launch_tiled()` not returning a `Launch` object when passed `record_cmd=True`.
 - Mark kernel arrays as written to when passed to `wp.atomic_add()` or `wp.atomic_sub()`
+- Fix default arguments not being resolved for `wp.func` when called from Python's runtime ([GH-386](https://github.com/NVIDIA/warp/issues/386)).
 
 ## [1.5.0] - 2024-12-02
 
diff --git a/warp/context.py b/warp/context.py
index d4092c4e2..c368d3493 100644
--- a/warp/context.py
+++ b/warp/context.py
@@ -293,22 +293,22 @@ def __call__(self, *args, **kwargs):
 
         if hasattr(self, "user_overloads") and len(self.user_overloads):
             # user-defined function with overloads
+            bound_args = self.signature.bind(*args, **kwargs)
+            if self.defaults:
+                warp.codegen.apply_defaults(bound_args, self.defaults)
 
-            if len(kwargs):
-                raise RuntimeError(
-                    f"Error calling function '{self.key}', keyword arguments are not supported for user-defined overloads."
-                )
+            arguments = tuple(bound_args.arguments.values())
 
             # try and find a matching overload
             for overload in self.user_overloads.values():
-                if len(overload.input_types) != len(args):
+                if len(overload.input_types) != len(arguments):
                     continue
                 template_types = list(overload.input_types.values())
                 arg_names = list(overload.input_types.keys())
                 try:
                     # attempt to unify argument types with function template types
-                    warp.types.infer_argument_types(args, template_types, arg_names)
-                    return overload.func(*args)
+                    warp.types.infer_argument_types(arguments, template_types, arg_names)
+                    return overload.func(*arguments)
                 except Exception:
                     continue
 
diff --git a/warp/tests/test_func.py b/warp/tests/test_func.py
index 0b39891cd..e15481b4b 100644
--- a/warp/tests/test_func.py
+++ b/warp/tests/test_func.py
@@ -162,7 +162,7 @@ def user_func_with_defaults(a: int = 123, b: int = 234) -> int:
 
 
 @wp.kernel
-def test_user_func_with_defaults():
+def user_func_with_defaults_kernel():
     a = user_func_with_defaults()
     wp.expect_eq(a, 357)
 
@@ -179,6 +179,25 @@ def test_user_func_with_defaults():
     wp.expect_eq(e, 234)
 
 
+def test_user_func_with_defaults(test, device):
+    wp.launch(user_func_with_defaults_kernel, dim=1, device=device)
+
+    a = user_func_with_defaults()
+    assert a == 357
+
+    b = user_func_with_defaults(111)
+    assert b == 345
+
+    c = user_func_with_defaults(111, 222)
+    assert c == 333
+
+    d = user_func_with_defaults(a=111)
+    assert d == 345
+
+    e = user_func_with_defaults(b=111)
+    assert e == 234
+
+
 @wp.func
 def user_func_return_multiple_values(a: int, b: float) -> Tuple[int, float]:
     return a + a, b * b
@@ -406,9 +425,7 @@ def test_native_function_error_resolution(self):
 add_function_test(TestFunc, func=test_multi_valued_func, name="test_multi_valued_func", devices=devices)
 add_kernel_test(TestFunc, kernel=test_func_defaults, name="test_func_defaults", dim=1, devices=devices)
 add_kernel_test(TestFunc, kernel=test_builtin_shadowing, name="test_builtin_shadowing", dim=1, devices=devices)
-add_kernel_test(
-    TestFunc, kernel=test_user_func_with_defaults, name="test_user_func_with_defaults", dim=1, devices=devices
-)
+add_function_test(TestFunc, func=test_user_func_with_defaults, name="test_user_func_with_defaults", devices=devices)
 add_kernel_test(
     TestFunc,
     kernel=test_user_func_return_multiple_values,