diff --git a/pkgs/development/python-modules/proboscis/default.nix b/pkgs/development/python-modules/proboscis/default.nix
deleted file mode 100644
index f6285605c3998..0000000000000
--- a/pkgs/development/python-modules/proboscis/default.nix
+++ /dev/null
@@ -1,21 +0,0 @@
-{ lib, buildPythonPackage, fetchPypi, nose }:
-
-buildPythonPackage rec {
-  pname = "proboscis";
-  version = "1.2.6.0";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "b822b243a7c82030fce0de97bdc432345941306d2c24ef227ca561dd019cd238";
-  };
-
-  propagatedBuildInputs = [ nose ];
-  doCheck = false;
-
-  meta = with lib; {
-    description = "A Python test framework that extends Python's built-in unittest module and Nose with features from TestNG";
-    homepage = "https://pypi.python.org/pypi/proboscis";
-    license = licenses.asl20;
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 0ecfbff848ca9..98e3e34abcc98 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -328,6 +328,7 @@ mapAliases ({
   postorius = throw "Please use pkgs.mailmanPackages.postorius"; # added 2022-04-29
   powerlineMemSegment = powerline-mem-segment; # added 2021-10-08
   privacyidea-ldap-proxy = throw "privacyidea-ldap-proxy has been removed from nixpkgs"; # added 2023-10-31
+  proboscis = throw "proboscis has been removed since it has not been maintained for 11 years"; # added 2024-05-20
   prometheus_client = prometheus-client; # added 2021-06-10
   prompt_toolkit = prompt-toolkit; # added 2021-07-22
   protonup = protonup-ng; # Added 2022-11-06
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index bf7c81ccf94f2..3f5a980ab0250 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10357,8 +10357,6 @@ self: super: with self; {
 
   prison = callPackage ../development/python-modules/prison { };
 
-  proboscis = callPackage ../development/python-modules/proboscis { };
-
   process-tests = callPackage ../development/python-modules/process-tests { };
 
   procmon-parser = callPackage ../development/python-modules/procmon-parser { };