diff --git a/extensions/default/src/DicomWebDataSource/index.ts b/extensions/default/src/DicomWebDataSource/index.ts
index 6bf6c4e12d3..676b54bbb6c 100644
--- a/extensions/default/src/DicomWebDataSource/index.ts
+++ b/extensions/default/src/DicomWebDataSource/index.ts
@@ -67,6 +67,8 @@ export type DicomWebConfig = {
   staticWado?: boolean;
   /** User authentication service */
   userAuthenticationService: Record<string, unknown>;
+  /** Case sensitivity configuration */
+  caseSensitive?: Record<string, boolean>;
 };
 
 export type BulkDataURIConfig = {
@@ -147,6 +149,7 @@ function createDicomWebApi(dicomWebConfig: DicomWebConfig, servicesManager) {
 
       qidoConfig = {
         url: dicomWebConfig.qidoRoot,
+        caseSensitive: dicomWebConfig.caseSensitive || {},
         staticWado: dicomWebConfig.staticWado,
         singlepart: dicomWebConfig.singlepart,
         headers: userAuthenticationService.getAuthorizationHeader(),
@@ -155,6 +158,7 @@ function createDicomWebApi(dicomWebConfig: DicomWebConfig, servicesManager) {
 
       wadoConfig = {
         url: dicomWebConfig.wadoRoot,
+        caseSensitive: dicomWebConfig.caseSensitive || {},
         staticWado: dicomWebConfig.staticWado,
         singlepart: dicomWebConfig.singlepart,
         headers: userAuthenticationService.getAuthorizationHeader(),
diff --git a/extensions/default/src/DicomWebDataSource/utils/StaticWadoClient.ts b/extensions/default/src/DicomWebDataSource/utils/StaticWadoClient.ts
index 519e8109c03..1c9baf87766 100644
--- a/extensions/default/src/DicomWebDataSource/utils/StaticWadoClient.ts
+++ b/extensions/default/src/DicomWebDataSource/utils/StaticWadoClient.ts
@@ -156,18 +156,27 @@ export default class StaticWadoClient extends api.DICOMwebClient {
    *
    * @param {*} desired
    * @param {*} actual
+   * @param {boolean} caseSensitive
    * @returns true if the values match
    */
-  compareValues(desired, actual) {
+  compareValues(desired, actual, caseSensitive = true) {
     if (Array.isArray(desired)) {
-      return desired.find(item => this.compareValues(item, actual));
+      return desired.find(item => this.compareValues(item, actual, caseSensitive));
     }
     if (Array.isArray(actual)) {
-      return actual.find(actualItem => this.compareValues(desired, actualItem));
+      return actual.find(actualItem => this.compareValues(desired, actualItem, caseSensitive));
     }
     if (actual?.Alphabetic) {
       actual = actual.Alphabetic;
     }
+
+    if (typeof actual == 'string') {
+      if (!caseSensitive) {
+        desired = desired.toLowerCase();
+        actual = actual.toLowerCase();
+      }
+    }
+
     if (typeof actual == 'string') {
       if (actual.length === 0) {
         return true;
@@ -227,7 +236,9 @@ export default class StaticWadoClient extends api.DICOMwebClient {
       return this.compareDateRange(testValue, valueElem.Value[0]);
     }
     const value = valueElem.Value;
-    return this.compareValues(testValue, value);
+    const caseSensitive = this.config.caseSensitive[key];
+
+    return this.compareValues(testValue, value, caseSensitive);
   }
 
   /** Converts the query parameters to lower case query parameters */
diff --git a/platform/app/public/config/default.js b/platform/app/public/config/default.js
index 1b118b5b067..ba63736e836 100644
--- a/platform/app/public/config/default.js
+++ b/platform/app/public/config/default.js
@@ -53,6 +53,12 @@ window.config = {
         supportsFuzzyMatching: false,
         supportsWildcard: true,
         staticWado: true,
+        caseSensitive: {
+          patientname: false,
+          studydescription: false,
+          accessionnumber: false,
+          '00100020': false,
+        },
         singlepart: 'bulkdata,video',
         // whether the data source should use retrieveBulkData to grab metadata,
         // and in case of relative path, what would it be relative to, options
diff --git a/platform/app/public/config/e2e.js b/platform/app/public/config/e2e.js
index 25fab2917aa..d3937fd098b 100644
--- a/platform/app/public/config/e2e.js
+++ b/platform/app/public/config/e2e.js
@@ -46,6 +46,12 @@ window.config = {
           relativeResolution: 'studies',
           transform: url => url.replace('/pixeldata.mp4', '/index.mp4'),
         },
+        caseSensitive: {
+          patientname: false,
+          studydescription: false,
+          accessionnumber: false,
+          '00100020': false,
+        },
       },
     },
     {
@@ -118,6 +124,12 @@ window.config = {
           relativeResolution: 'studies',
           transform: url => url.replace('/pixeldata.mp4', '/rendered'),
         },
+        caseSensitive: {
+          patientname: false,
+          studydescription: false,
+          accessionnumber: false,
+          '00100020': false,
+        },
       },
     },
 
diff --git a/platform/docs/docs/configuration/configurationFiles.md b/platform/docs/docs/configuration/configurationFiles.md
index db24e8da95f..f7865332d36 100644
--- a/platform/docs/docs/configuration/configurationFiles.md
+++ b/platform/docs/docs/configuration/configurationFiles.md
@@ -193,6 +193,15 @@ if auth headers are used, a preflight request is required.
 - `activateViewportBeforeInteraction`: (default to true), if set to false, tools can be used directly without the need to click and activate the viewport.
 - `autoPlayCine`: (default to false), if set to true, data sets with the DICOM frame time tag (i.e. (0018,1063)) will auto play when displayed
 - `addWindowLevelActionMenu`: (default to true), if set to false, the window level action menu item is NOT added to the viewport action corners
+- `caseSensitive`: an object with filter keys that should be case sensitive, only works on STATIC-WADO backends. By default, all filters are case sensitive. If you want to set a filter to be case insensitive, you can set it to false. Example:
+  ```js
+  caseSensitive: {
+    patientname: false,
+    studydescription: false,
+    accessionnumber: false,
+    '00100020': false,
+  }
+  ```
 - `dangerouslyUseDynamicConfig`: Dynamic config allows user to pass `configUrl` query string. This allows to load config without recompiling application. If the `configUrl` query string is passed, the worklist and modes will load from the referenced json rather than the default .env config. If there is no `configUrl` path provided, the default behaviour is used and there should not be any deviation from current user experience.<br/>
 Points to consider while using `dangerouslyUseDynamicConfig`:<br/>
   - User have to enable this feature by setting `dangerouslyUseDynamicConfig.enabled:true`. By default it is `false`.