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27.3768 10.1948 13.2084 C 0 0 0 0 0 0 + 27.8322 10.8314 14.5056 C 0 0 1 0 0 0 + 27.8542 11.9112 14.3444 H 0 0 0 0 0 0 + 26.9119 10.5394 15.5582 O 0 0 0 0 0 0 + 27.1871 11.2368 16.7664 C 0 0 1 0 0 0 + 27.2533 12.2986 16.5203 H 0 0 0 0 0 0 + 25.9646 11.0756 17.7107 C 0 0 0 0 0 0 + 25.7435 12.0295 18.1935 H 0 0 0 0 0 0 + 25.0828 10.8430 17.1121 H 0 0 0 0 0 0 + 26.1084 10.0349 18.7547 N 0 3 0 0 0 0 + 25.1934 9.6416 18.9279 H 0 0 0 0 0 0 + 26.6327 10.5135 20.0519 C 0 0 0 0 0 0 + 27.5335 11.1056 19.9073 H 0 0 0 0 0 0 + 25.8953 11.1729 20.5131 H 0 0 0 0 0 0 + 26.9337 9.3346 20.9797 C 0 0 0 0 0 0 + 26.0086 8.8027 21.2109 H 0 0 0 0 0 0 + 27.5913 8.6278 20.4745 H 0 0 0 0 0 0 + 27.5915 9.7745 22.2033 N 0 0 0 0 0 0 + 28.1183 10.6349 22.1777 H 0 0 0 0 0 0 + 27.5845 9.0812 23.3501 C 0 0 0 0 0 0 + 26.9602 8.0341 23.4991 O 0 0 0 0 0 0 + 28.4080 9.6461 24.5016 C 0 0 0 0 0 0 + 28.7872 10.6444 24.2772 H 0 0 0 0 0 0 + 29.2581 8.9934 24.7029 H 0 0 0 0 0 0 + 27.8018 9.7048 25.4067 H 0 0 0 0 0 0 + 28.5584 10.7639 17.3032 C 0 0 0 0 0 0 + 28.8426 11.3272 18.1901 H 0 0 0 0 0 0 + 28.5175 9.7113 17.5858 H 0 0 0 0 0 0 + 29.6536 10.9530 16.2469 C 0 0 0 0 0 0 + 29.8320 12.0218 16.1159 H 0 0 0 0 0 0 + 30.5966 10.5408 16.6027 H 0 0 0 0 0 0 + 29.2441 10.3500 14.8882 C 0 0 1 0 0 0 + 29.9353 10.7553 14.1469 H 0 0 0 0 0 0 + 30.8534 7.4269 16.2913 C 0 0 0 0 0 0 + 29.9891 7.1119 16.8557 H 0 0 0 0 0 0 + 32.1359 6.9881 16.6735 C 0 0 0 0 0 0 + 32.2478 6.3369 17.5280 H 0 0 0 0 0 0 + 26.6930 9.2959 18.3885 H 0 0 0 0 0 0 + 1 2 1 0 0 0 + 2 56 1 0 0 0 + 2 3 2 0 0 0 + 3 4 1 0 0 0 + 3 5 1 0 0 0 + 5 6 1 0 0 0 + 5 7 2 0 0 0 + 7 8 1 0 0 0 + 7 54 1 0 0 0 + 8 52 1 0 0 0 + 8 9 1 0 0 0 + 8 10 1 0 0 0 + 10 11 1 0 0 0 + 10 12 1 0 0 0 + 12 21 1 0 0 0 + 12 13 2 0 0 0 + 13 14 1 0 0 0 + 13 15 1 0 0 0 + 15 16 1 0 0 0 + 15 17 2 0 0 0 + 17 18 1 0 0 0 + 17 19 1 0 0 0 + 19 20 1 0 0 0 + 19 21 2 0 0 0 + 21 22 1 0 0 0 + 22 52 1 0 0 0 + 22 23 1 0 0 0 + 22 24 1 0 0 0 + 24 25 1 0 0 0 + 25 26 1 0 0 0 + 25 27 1 0 0 0 + 25 46 1 0 0 0 + 27 28 1 0 0 0 + 27 29 1 0 0 0 + 27 30 1 0 0 0 + 30 31 1 0 0 0 + 30 32 1 0 0 0 + 30 58 1 0 0 0 + 32 33 1 0 0 0 + 32 34 1 0 0 0 + 32 35 1 0 0 0 + 35 36 1 0 0 0 + 35 37 1 0 0 0 + 35 38 1 0 0 0 + 38 39 1 0 0 0 + 38 40 1 0 0 0 + 40 41 2 0 0 0 + 40 42 1 0 0 0 + 42 43 1 0 0 0 + 42 44 1 0 0 0 + 42 45 1 0 0 0 + 46 47 1 0 0 0 + 46 48 1 0 0 0 + 46 49 1 0 0 0 + 49 50 1 0 0 0 + 49 51 1 0 0 0 + 49 52 1 0 0 0 + 52 53 1 0 0 0 + 54 55 1 0 0 0 + 54 56 2 0 0 0 + 56 57 1 0 0 0 +M CHG 1 30 1 +M END +> +ligprep_eg5.smi + +> +7 + +> +53161 + +> +0 + +> +RmMxW2NIXWMoQnIpW2NIXWMoYzEyKVtDQEBIXTNbQ0BIXShbQ0BASF0oW05IXTIpYzRbY0hdW2NIXVtjSF1bY0hdW2NIXTQpW0NIMl1bQ0gyXVtDQEBIXShPMylbQ0gyXVtOSF1bQ0gyXVtDSDJdW05IXUMoPU8pW0NIM10= + +> +J2VwaWtfcHl0aG9uJywgJy1waHQnLCAnMC4wJywgJy1waCcsICc3LjQnLCAnLXRuJywgJzgnLCAnLW1hJywgJzUwMCcsICctaW1hZScsICc8aW5maWxlLm1hZT4nLCAnLW9tYWUnLCAnPG91dGZpbGUubWFlPic= + +> +1 + +> + 0.0077 + +> + 0.0077 + +> + 0.0000 + +> + -0.0000 + +> +0.00765215 + +> +1 + +> +1 + +> +S-OPLS + +> +33.3357 + +> +1 + +> +lig_CHEMBL1082249-1 + +> +glide-grid_EG5-3L9H + +> +7 + +> +7 + +> +-7.11232702404811 + +> +-0.23707756746827 + +> +-0.736655123234709 + +> +-1.61599819487352 + +> +-7.11232702404811 + +> +-4.55664998253593 + +> +-0.0816780435388489 + +> +-0 + +> +-0.348176918870169 + +> +-46.5956993103027 + +> +-2.19561052322388 + +> +0.533304464895562 + +> +0 + +> +-67.8709711424982 + +> +-48.7913098335266 + +> +0.845360338687897 + +> +30 + +> +28 + +> +-0 + +> +0.0850935331009369 + +> +snapped_core_restrain + +$$$$ diff --git a/cofactors/eg5_protein.pdb b/cofactors/eg5_protein.pdb new file mode 100644 index 0000000..01ca8bb --- /dev/null +++ b/cofactors/eg5_protein.pdb @@ -0,0 +1,5917 @@ +HEADER MOTOR PROTEIN 05-JAN-10 3L9H +TITLE X-RAY STRUCTURE OF MITOTIC KINESIN-5 (KSP, KIF11, EG5)IN +TITLE 2 COMPLEX WITH THE HEXAHYDRO-2H-PYRANO[3,2-C]QUINOLINE EMD +TITLE 3 534085 +EXPDTA X-RAY DIFFRACTION +REMARK 2 RESOLUTION. 2.00 ANGSTROMS +REMARK 3 R VALUE : 0.234000 +REMARK 3 FREE R VALUE : 0.258000 +REMARK 4 3L9H COMPLIES WITH FORMAT V. 3.20, 01-DEC-08 +REMARK 200 TEMPERATURE (KELVIN) : 100.00 +REMARK 200 PH : 7.00 +REMARK 350 BIOMOLECULE: 1 +REMARK 350 APPLY THE FOLLOWING TO CHAINS: A +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.000000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.000000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.000000 +REMARK 350 BIOMOLECULE: 2 +REMARK 350 APPLY THE FOLLOWING TO CHAINS: B +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.000000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.000000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.000000 +REMARK 888 +REMARK 888 WRITTEN BY MAESTRO (A PRODUCT OF SCHRODINGER, LLC) +SEQRES 1 A 349 ACE GLY LYS ASN ILE GLN VAL VAL VAL ARG CYS ARG PRO +SEQRES 2 A 349 PHE ASN LEU ALA GLU ARG LYS ALA SER ALA HIS SER ILE +SEQRES 3 A 349 VAL GLU CYS ASP PRO VAL ARG LYS GLU VAL SER VAL ARG +SEQRES 4 A 349 THR GLY GLY LEU ALA ASP LYS SER SER ARG LYS THR TYR +SEQRES 5 A 349 THR PHE ASP MET VAL PHE GLY ALA SER THR LYS GLN ILE +SEQRES 6 A 349 ASP VAL TYR ARG SER VAL VAL CYS PRO ILE LEU ASP GLU +SEQRES 7 A 349 VAL ILE MET GLY TYR ASN CYS THR ILE PHE ALA TYR GLY +SEQRES 8 A 349 GLN THR GLY THR GLY LYS THR PHE THR MET GLU GLY GLU +SEQRES 9 A 349 ARG SER PRO ASN GLU GLU TYR THR TRP GLU GLU ASP PRO +SEQRES 10 A 349 LEU ALA GLY ILE ILE PRO ARG THR LEU HIS GLN ILE PHE +SEQRES 11 A 349 GLU LYS LEU THR ASP ASN GLY THR GLU PHE SER VAL LYS +SEQRES 12 A 349 VAL SER LEU LEU GLU ILE TYR ASN GLU GLU LEU PHE ASP +SEQRES 13 A 349 LEU LEU ASN PRO SER SER ASP VAL SER GLU ARG LEU GLN +SEQRES 14 A 349 MET PHE ASP ASP PRO ARG ASN LYS ARG GLY VAL ILE ILE +SEQRES 15 A 349 LYS GLY LEU GLU GLU ILE THR VAL HIS ASN LYS ASP GLU +SEQRES 16 A 349 VAL TYR GLN ILE LEU GLU LYS GLY ALA ALA LYS ARG THR +SEQRES 17 A 349 THR ALA ALA THR LEU MET ASN ALA TYR SER SER ARG SER +SEQRES 18 A 349 HIS SER VAL PHE SER VAL THR ILE HIS MET LYS GLU THR +SEQRES 19 A 349 THR ILE ASP GLY GLU GLU LEU VAL LYS ILE GLY LYS LEU +SEQRES 20 A 349 ASN LEU VAL ASP LEU ALA GLY SER GLU ASN ILE GLY ARG +SEQRES 21 A 349 SER GLY ALA VAL ASP LYS ARG ALA ARG GLU ALA GLY ASN +SEQRES 22 A 349 ILE ASN GLN SER LEU LEU THR LEU GLY ARG VAL ILE THR +SEQRES 23 A 349 ALA LEU VAL GLU ARG THR PRO HIS VAL PRO TYR ARG GLU +SEQRES 24 A 349 SER LYS LEU THR ARG ILE LEU GLN ASP SER LEU GLY GLY +SEQRES 25 A 349 ARG THR ARG THR SER ILE ILE ALA THR ILE SER PRO ALA +SEQRES 26 A 349 SER LEU ASN LEU GLU GLU THR LEU SER THR LEU GLU TYR +SEQRES 27 A 349 ALA HIS ARG ALA LYS ASN ILE LEU ASN LYS NME +FORMUL 2 HOH *7(H2 0) +HELIX 1 1 LEU A 30 LEU A 30 1 +HELIX 2 2 ALA A 31 ALA A 31 1 +HELIX 3 3 GLU A 32 GLU A 32 1 +HELIX 4 4 ARG A 33 ARG A 33 1 +HELIX 5 5 GLN A 78 GLN A 78 1 +HELIX 6 6 ILE A 79 ILE A 79 1 +HELIX 7 7 ASP A 80 ASP A 80 1 +HELIX 8 8 VAL A 81 VAL A 81 1 +HELIX 9 9 TYR A 82 TYR A 82 1 +HELIX 10 10 ARG A 83 ARG A 83 1 +HELIX 11 11 SER A 84 SER A 84 1 +HELIX 12 12 CYS A 87 CYS A 87 1 +HELIX 13 13 PRO A 88 PRO A 88 1 +HELIX 14 14 ILE A 89 ILE A 89 1 +HELIX 15 15 LEU A 90 LEU A 90 1 +HELIX 16 16 ASP A 91 ASP A 91 1 +HELIX 17 17 GLU A 92 GLU A 92 1 +HELIX 18 18 VAL A 93 VAL A 93 1 +HELIX 19 19 ILE A 94 ILE A 94 1 +HELIX 20 20 LYS A 111 LYS A 111 1 +HELIX 21 21 THR A 112 THR A 112 1 +HELIX 22 22 PHE A 113 PHE A 113 1 +HELIX 23 23 THR A 114 THR A 114 1 +HELIX 24 24 MET A 115 MET A 115 1 +HELIX 25 25 ILE A 136 ILE A 136 1 +HELIX 26 26 PRO A 137 PRO A 137 1 +HELIX 27 27 ARG A 138 ARG A 138 1 +HELIX 28 28 THR A 139 THR A 139 1 +HELIX 29 29 LEU A 140 LEU A 140 1 +HELIX 30 30 HIS A 141 HIS A 141 1 +HELIX 31 31 GLN A 142 GLN A 142 1 +HELIX 32 32 ILE A 143 ILE A 143 1 +HELIX 33 33 PHE A 144 PHE A 144 1 +HELIX 34 34 GLU A 145 GLU A 145 1 +HELIX 35 35 LYS A 146 LYS A 146 1 +HELIX 36 36 VAL A 210 VAL A 210 1 +HELIX 37 37 TYR A 211 TYR A 211 1 +HELIX 38 38 GLN A 212 GLN A 212 1 +HELIX 39 39 ILE A 213 ILE A 213 1 +HELIX 40 40 LEU A 214 LEU A 214 1 +HELIX 41 41 GLU A 215 GLU A 215 1 +HELIX 42 42 LYS A 216 LYS A 216 1 +HELIX 43 43 GLY A 217 GLY A 217 1 +HELIX 44 44 ALA A 218 ALA A 218 1 +HELIX 45 45 ALA A 219 ALA A 219 1 +HELIX 46 46 LYS A 220 LYS A 220 1 +HELIX 47 47 ARG A 221 ARG A 221 1 +HELIX 48 48 THR A 222 THR A 222 1 +HELIX 49 49 THR A 223 THR A 223 1 +HELIX 50 50 ALA A 224 ALA A 224 1 +HELIX 51 51 ALA A 225 ALA A 225 1 +HELIX 52 52 THR A 226 THR A 226 1 +HELIX 53 53 LEU A 227 LEU A 227 1 +HELIX 54 54 TYR A 231 TYR A 231 1 +HELIX 55 55 SER A 232 SER A 232 1 +HELIX 56 56 SER A 233 SER A 233 1 +HELIX 57 57 ARG A 234 ARG A 234 1 +HELIX 58 58 GLN A 290 GLN A 290 1 +HELIX 59 59 SER A 291 SER A 291 1 +HELIX 60 60 LEU A 292 LEU A 292 1 +HELIX 61 61 LEU A 293 LEU A 293 1 +HELIX 62 62 THR A 294 THR A 294 1 +HELIX 63 63 LEU A 295 LEU A 295 1 +HELIX 64 64 GLY A 296 GLY A 296 1 +HELIX 65 65 ARG A 297 ARG A 297 1 +HELIX 66 66 VAL A 298 VAL A 298 1 +HELIX 67 67 ILE A 299 ILE A 299 1 +HELIX 68 68 THR A 300 THR A 300 1 +HELIX 69 69 ALA A 301 ALA A 301 1 +HELIX 70 70 LEU A 302 LEU A 302 1 +HELIX 71 71 VAL A 303 VAL A 303 1 +HELIX 72 72 LYS A 315 LYS A 315 1 +HELIX 73 73 LEU A 316 LEU A 316 1 +HELIX 74 74 THR A 317 THR A 317 1 +HELIX 75 75 ARG A 318 ARG A 318 1 +HELIX 76 76 ILE A 319 ILE A 319 1 +HELIX 77 77 LEU A 343 LEU A 343 1 +HELIX 78 78 GLU A 344 GLU A 344 1 +HELIX 79 79 GLU A 345 GLU A 345 1 +HELIX 80 80 THR A 346 THR A 346 1 +HELIX 81 81 LEU A 347 LEU A 347 1 +HELIX 82 82 SER A 348 SER A 348 1 +HELIX 83 83 THR A 349 THR A 349 1 +HELIX 84 84 LEU A 350 LEU A 350 1 +HELIX 85 85 GLU A 351 GLU A 351 1 +HELIX 86 86 TYR A 352 TYR A 352 1 +HELIX 87 87 ALA A 353 ALA A 353 1 +HELIX 88 88 HIS A 354 HIS A 354 1 +HELIX 89 89 ARG A 355 ARG A 355 1 +HELIX 90 90 ALA A 356 ALA A 356 1 +TURN 1 1 GLY A 16 GLY A 16 +TURN 2 2 LYS A 17 LYS A 17 +TURN 3 3 ASN A 18 ASN A 18 +TURN 4 4 ILE A 19 ILE A 19 +TURN 5 5 GLN A 20 GLN A 20 +TURN 6 6 VAL A 21 VAL A 21 +TURN 7 7 CYS A 25 CYS A 25 +TURN 8 8 ARG A 26 ARG A 26 +TURN 9 9 PRO A 27 PRO A 27 +TURN 10 10 PHE A 28 PHE A 28 +TURN 11 11 ASN A 29 ASN A 29 +TURN 12 12 LYS A 34 LYS A 34 +TURN 13 13 ALA A 35 ALA A 35 +TURN 14 14 SER A 36 SER A 36 +TURN 15 15 ALA A 37 ALA A 37 +TURN 16 16 HIS A 38 HIS A 38 +TURN 17 17 SER A 39 SER A 39 +TURN 18 18 ILE A 40 ILE A 40 +TURN 19 19 PRO A 45 PRO A 45 +TURN 20 20 VAL A 46 VAL A 46 +TURN 21 21 ARG A 47 ARG A 47 +TURN 22 22 LYS A 48 LYS A 48 +TURN 23 23 LEU A 57 LEU A 57 +TURN 24 24 ALA A 58 ALA A 58 +TURN 25 25 ASP A 59 ASP A 59 +TURN 26 26 LYS A 60 LYS A 60 +TURN 27 27 PHE A 68 PHE A 68 +TURN 28 28 ASP A 69 ASP A 69 +TURN 29 29 GLY A 73 GLY A 73 +TURN 30 30 ALA A 74 ALA A 74 +TURN 31 31 SER A 75 SER A 75 +TURN 32 32 THR A 76 THR A 76 +TURN 33 33 LYS A 77 LYS A 77 +TURN 34 34 VAL A 85 VAL A 85 +TURN 35 35 VAL A 86 VAL A 86 +TURN 36 36 MET A 95 MET A 95 +TURN 37 37 GLY A 96 GLY A 96 +TURN 38 38 TYR A 97 TYR A 97 +TURN 39 39 TYR A 104 TYR A 104 +TURN 40 40 GLY A 105 GLY A 105 +TURN 41 41 GLN A 106 GLN A 106 +TURN 42 42 THR A 107 THR A 107 +TURN 43 43 GLY A 108 GLY A 108 +TURN 44 44 THR A 109 THR A 109 +TURN 45 45 GLY A 110 GLY A 110 +TURN 46 46 GLU A 116 GLU A 116 +TURN 47 47 GLY A 117 GLY A 117 +TURN 48 48 GLU A 118 GLU A 118 +TURN 49 49 ARG A 119 ARG A 119 +TURN 50 50 SER A 120 SER A 120 +TURN 51 51 PRO A 121 PRO A 121 +TURN 52 52 ASN A 122 ASN A 122 +TURN 53 53 GLU A 123 GLU A 123 +TURN 54 54 GLU A 124 GLU A 124 +TURN 55 55 TYR A 125 TYR A 125 +TURN 56 56 THR A 126 THR A 126 +TURN 57 57 TRP A 127 TRP A 127 +TURN 58 58 GLU A 128 GLU A 128 +TURN 59 59 GLU A 129 GLU A 129 +TURN 60 60 ASP A 130 ASP A 130 +TURN 61 61 PRO A 131 PRO A 131 +TURN 62 62 LEU A 132 LEU A 132 +TURN 63 63 ALA A 133 ALA A 133 +TURN 64 64 GLY A 134 GLY A 134 +TURN 65 65 ILE A 135 ILE A 135 +TURN 66 66 LEU A 147 LEU A 147 +TURN 67 67 THR A 148 THR A 148 +TURN 68 68 ASP A 149 ASP A 149 +TURN 69 69 ASN A 150 ASN A 150 +TURN 70 70 GLY A 151 GLY A 151 +TURN 71 71 THR A 152 THR A 152 +TURN 72 72 ASN A 165 ASN A 165 +TURN 73 73 GLU A 166 GLU A 166 +TURN 74 74 LEU A 171 LEU A 171 +TURN 75 75 LEU A 172 LEU A 172 +TURN 76 76 ASN A 173 ASN A 173 +TURN 77 77 PRO A 174 PRO A 174 +TURN 78 78 SER A 175 SER A 175 +TURN 79 79 SER A 176 SER A 176 +TURN 80 80 ASP A 177 ASP A 177 +TURN 81 81 VAL A 178 VAL A 178 +TURN 82 82 SER A 179 SER A 179 +TURN 83 83 GLU A 180 GLU A 180 +TURN 84 84 ASP A 187 ASP A 187 +TURN 85 85 PRO A 188 PRO A 188 +TURN 86 86 ARG A 189 ARG A 189 +TURN 87 87 ASN A 190 ASN A 190 +TURN 88 88 LYS A 191 LYS A 191 +TURN 89 89 ARG A 192 ARG A 192 +TURN 90 90 GLY A 193 GLY A 193 +TURN 91 91 GLY A 198 GLY A 198 +TURN 92 92 LEU A 199 LEU A 199 +TURN 93 93 GLU A 200 GLU A 200 +TURN 94 94 GLU A 201 GLU A 201 +TURN 95 95 VAL A 204 VAL A 204 +TURN 96 96 HIS A 205 HIS A 205 +TURN 97 97 ASN A 206 ASN A 206 +TURN 98 98 LYS A 207 LYS A 207 +TURN 99 99 ASP A 208 ASP A 208 +TURN 100 100 GLU A 209 GLU A 209 +TURN 101 101 MET A 228 MET A 228 +TURN 102 102 ASN A 229 ASN A 229 +TURN 103 103 ALA A 230 ALA A 230 +TURN 104 104 SER A 235 SER A 235 +TURN 105 105 THR A 249 THR A 249 +TURN 106 106 ILE A 250 ILE A 250 +TURN 107 107 ASP A 251 ASP A 251 +TURN 108 108 GLY A 252 GLY A 252 +TURN 109 109 GLU A 253 GLU A 253 +TURN 110 110 LEU A 266 LEU A 266 +TURN 111 111 ALA A 267 ALA A 267 +TURN 112 112 GLY A 268 GLY A 268 +TURN 113 113 SER A 269 SER A 269 +TURN 114 114 GLU A 270 GLU A 270 +TURN 115 115 ASN A 271 ASN A 271 +TURN 116 116 ILE A 272 ILE A 272 +TURN 117 117 GLY A 273 GLY A 273 +TURN 118 118 ARG A 274 ARG A 274 +TURN 119 119 SER A 275 SER A 275 +TURN 120 120 GLY A 276 GLY A 276 +TURN 121 121 ALA A 277 ALA A 277 +TURN 122 122 VAL A 278 VAL A 278 +TURN 123 123 ASP A 279 ASP A 279 +TURN 124 124 LYS A 280 LYS A 280 +TURN 125 125 ARG A 281 ARG A 281 +TURN 126 126 ALA A 282 ALA A 282 +TURN 127 127 ARG A 283 ARG A 283 +TURN 128 128 GLU A 284 GLU A 284 +TURN 129 129 ALA A 285 ALA A 285 +TURN 130 130 GLY A 286 GLY A 286 +TURN 131 131 ASN A 287 ASN A 287 +TURN 132 132 ILE A 288 ILE A 288 +TURN 133 133 ASN A 289 ASN A 289 +TURN 134 134 GLU A 304 GLU A 304 +TURN 135 135 ARG A 305 ARG A 305 +TURN 136 136 THR A 306 THR A 306 +TURN 137 137 PRO A 307 PRO A 307 +TURN 138 138 HIS A 308 HIS A 308 +TURN 139 139 VAL A 309 VAL A 309 +TURN 140 140 PRO A 310 PRO A 310 +TURN 141 141 TYR A 311 TYR A 311 +TURN 142 142 ARG A 312 ARG A 312 +TURN 143 143 GLU A 313 GLU A 313 +TURN 144 144 SER A 314 SER A 314 +TURN 145 145 LEU A 320 LEU A 320 +TURN 146 146 GLN A 321 GLN A 321 +TURN 147 147 ASP A 322 ASP A 322 +TURN 148 148 SER A 323 SER A 323 +TURN 149 149 LEU A 324 LEU A 324 +TURN 150 150 GLY A 325 GLY A 325 +TURN 151 151 GLY A 326 GLY A 326 +TURN 152 152 ARG A 327 ARG A 327 +TURN 153 153 THR A 328 THR A 328 +TURN 154 154 ARG A 329 ARG A 329 +TURN 155 155 THR A 330 THR A 330 +TURN 156 156 SER A 331 SER A 331 +TURN 157 157 ILE A 332 ILE A 332 +TURN 158 158 ILE A 333 ILE A 333 +TURN 159 159 ALA A 334 ALA A 334 +TURN 160 160 THR A 335 THR A 335 +TURN 161 161 ILE A 336 ILE A 336 +TURN 162 162 SER A 337 SER A 337 +TURN 163 163 PRO A 338 PRO A 338 +TURN 164 164 ALA A 339 ALA A 339 +TURN 165 165 SER A 340 SER A 340 +TURN 166 166 LEU A 341 LEU A 341 +TURN 167 167 ASN A 342 ASN A 342 +TURN 168 168 LYS A 357 LYS A 357 +TURN 169 169 ASN A 358 ASN A 358 +TURN 170 170 ILE A 359 ILE A 359 +TURN 171 171 LEU A 360 LEU A 360 +TURN 172 172 ASN A 361 ASN A 361 +TURN 173 173 LYS A 362 LYS A 362 +SHEET 1 1 1 VAL A 22 VAL A 22 0 +SHEET 1 2 1 VAL A 23 VAL A 23 0 +SHEET 1 3 1 ARG A 24 ARG A 24 0 +SHEET 1 4 1 VAL A 41 VAL A 41 0 +SHEET 1 5 1 GLU A 42 GLU A 42 0 +SHEET 1 6 1 CYS A 43 CYS A 43 0 +SHEET 1 7 1 ASP A 44 ASP A 44 0 +SHEET 1 8 1 GLU A 49 GLU A 49 0 +SHEET 1 9 1 VAL A 50 VAL A 50 0 +SHEET 1 10 1 SER A 51 SER A 51 0 +SHEET 1 11 1 VAL A 52 VAL A 52 0 +SHEET 1 12 1 ARG A 53 ARG A 53 0 +SHEET 1 13 1 THR A 54 THR A 54 0 +SHEET 1 14 1 GLY A 55 GLY A 55 0 +SHEET 1 15 1 GLY A 56 GLY A 56 0 +SHEET 1 16 1 SER A 61 SER A 61 0 +SHEET 1 17 1 SER A 62 SER A 62 0 +SHEET 1 18 1 ARG A 63 ARG A 63 0 +SHEET 1 19 1 LYS A 64 LYS A 64 0 +SHEET 1 20 1 THR A 65 THR A 65 0 +SHEET 1 21 1 TYR A 66 TYR A 66 0 +SHEET 1 22 1 THR A 67 THR A 67 0 +SHEET 1 23 1 MET A 70 MET A 70 0 +SHEET 1 24 1 VAL A 71 VAL A 71 0 +SHEET 1 25 1 PHE A 72 PHE A 72 0 +SHEET 1 26 1 ASN A 98 ASN A 98 0 +SHEET 1 27 1 CYS A 99 CYS A 99 0 +SHEET 1 28 1 THR A 100 THR A 100 0 +SHEET 1 29 1 ILE A 101 ILE A 101 0 +SHEET 1 30 1 PHE A 102 PHE A 102 0 +SHEET 1 31 1 ALA A 103 ALA A 103 0 +SHEET 1 32 1 GLU A 153 GLU A 153 0 +SHEET 1 33 1 PHE A 154 PHE A 154 0 +SHEET 1 34 1 SER A 155 SER A 155 0 +SHEET 1 35 1 VAL A 156 VAL A 156 0 +SHEET 1 36 1 LYS A 157 LYS A 157 0 +SHEET 1 37 1 VAL A 158 VAL A 158 0 +SHEET 1 38 1 SER A 159 SER A 159 0 +SHEET 1 39 1 LEU A 160 LEU A 160 0 +SHEET 1 40 1 LEU A 161 LEU A 161 0 +SHEET 1 41 1 GLU A 162 GLU A 162 0 +SHEET 1 42 1 ILE A 163 ILE A 163 0 +SHEET 1 43 1 TYR A 164 TYR A 164 0 +SHEET 1 44 1 GLU A 167 GLU A 167 0 +SHEET 1 45 1 LEU A 168 LEU A 168 0 +SHEET 1 46 1 PHE A 169 PHE A 169 0 +SHEET 1 47 1 ASP A 170 ASP A 170 0 +SHEET 1 48 1 ARG A 181 ARG A 181 0 +SHEET 1 49 1 LEU A 182 LEU A 182 0 +SHEET 1 50 1 GLN A 183 GLN A 183 0 +SHEET 1 51 1 MET A 184 MET A 184 0 +SHEET 1 52 1 PHE A 185 PHE A 185 0 +SHEET 1 53 1 ASP A 186 ASP A 186 0 +SHEET 1 54 1 VAL A 194 VAL A 194 0 +SHEET 1 55 1 ILE A 195 ILE A 195 0 +SHEET 1 56 1 ILE A 196 ILE A 196 0 +SHEET 1 57 1 LYS A 197 LYS A 197 0 +SHEET 1 58 1 ILE A 202 ILE A 202 0 +SHEET 1 59 1 THR A 203 THR A 203 0 +SHEET 1 60 1 HIS A 236 HIS A 236 0 +SHEET 1 61 1 SER A 237 SER A 237 0 +SHEET 1 62 1 VAL A 238 VAL A 238 0 +SHEET 1 63 1 PHE A 239 PHE A 239 0 +SHEET 1 64 1 SER A 240 SER A 240 0 +SHEET 1 65 1 VAL A 241 VAL A 241 0 +SHEET 1 66 1 THR A 242 THR A 242 0 +SHEET 1 67 1 ILE A 243 ILE A 243 0 +SHEET 1 68 1 HIS A 244 HIS A 244 0 +SHEET 1 69 1 MET A 245 MET A 245 0 +SHEET 1 70 1 LYS A 246 LYS A 246 0 +SHEET 1 71 1 GLU A 247 GLU A 247 0 +SHEET 1 72 1 THR A 248 THR A 248 0 +SHEET 1 73 1 GLU A 254 GLU A 254 0 +SHEET 1 74 1 LEU A 255 LEU A 255 0 +SHEET 1 75 1 VAL A 256 VAL A 256 0 +SHEET 1 76 1 LYS A 257 LYS A 257 0 +SHEET 1 77 1 ILE A 258 ILE A 258 0 +SHEET 1 78 1 GLY A 259 GLY A 259 0 +SHEET 1 79 1 LYS A 260 LYS A 260 0 +SHEET 1 80 1 LEU A 261 LEU A 261 0 +SHEET 1 81 1 ASN A 262 ASN A 262 0 +SHEET 1 82 1 LEU A 263 LEU A 263 0 +SHEET 1 83 1 VAL A 264 VAL A 264 0 +SHEET 1 84 1 ASP A 265 ASP A 265 0 +CRYST1 160.950 79.718 69.513 90.00 96.88 90.00 C 1 2 1 8 +HETATM 1 CH3 ACE A 15 24.431 -17.877 -11.476 1.00 0.00 C +HETATM 2 C ACE A 15 24.674 -16.414 -11.124 1.00 0.00 C +HETATM 3 O ACE A 15 25.798 -15.931 -11.253 1.00 0.00 O +HETATM 4 H1 ACE A 15 25.311 -18.475 -11.239 1.00 0.00 H +HETATM 5 H2 ACE A 15 23.585 -18.282 -10.919 1.00 0.00 H +HETATM 6 H3 ACE A 15 24.223 -17.978 -12.542 1.00 0.00 H +ATOM 7 N GLY A 16 23.614 -15.724 -10.670 1.00 56.82 N +ATOM 8 CA GLY A 16 23.646 -14.323 -10.247 1.00 57.15 C +ATOM 9 C GLY A 16 24.213 -14.203 -8.825 1.00 56.24 C +ATOM 10 O GLY A 16 25.151 -14.910 -8.454 1.00 56.63 O +ATOM 11 H GLY A 16 22.728 -16.199 -10.583 1.00 56.82 H +ATOM 12 HA3 GLY A 16 22.635 -13.918 -10.293 1.00 57.15 H +ATOM 13 HA2 GLY A 16 24.256 -13.729 -10.929 1.00 57.15 H +ATOM 14 N LYS A 17 23.662 -13.267 -8.040 1.00 53.91 N +ATOM 15 CA LYS A 17 24.105 -13.003 -6.677 1.00 51.35 C +ATOM 16 C LYS A 17 22.888 -12.704 -5.798 1.00 48.72 C +ATOM 17 O LYS A 17 22.318 -11.618 -5.893 1.00 48.83 O +ATOM 18 CB LYS A 17 25.153 -11.868 -6.699 1.00 53.46 C +ATOM 19 CG LYS A 17 25.712 -11.461 -5.324 1.00 54.84 C +ATOM 20 CD LYS A 17 26.495 -12.582 -4.611 1.00 56.79 C +ATOM 21 CE LYS A 17 27.010 -12.193 -3.216 1.00 57.01 C +ATOM 22 NZ LYS A 17 28.016 -11.119 -3.266 1.00 59.10 N1+ +ATOM 23 H LYS A 17 22.912 -12.683 -8.386 1.00 53.91 H +ATOM 24 HA LYS A 17 24.578 -13.900 -6.274 1.00 51.35 H +ATOM 25 HB3 LYS A 17 24.714 -10.985 -7.167 1.00 53.46 H +ATOM 26 HB2 LYS A 17 25.987 -12.157 -7.341 1.00 53.46 H +ATOM 27 HG3 LYS A 17 24.896 -11.125 -4.688 1.00 54.84 H +ATOM 28 HG2 LYS A 17 26.353 -10.591 -5.464 1.00 54.84 H +ATOM 29 HD3 LYS A 17 27.325 -12.908 -5.240 1.00 56.79 H +ATOM 30 HD2 LYS A 17 25.855 -13.456 -4.490 1.00 56.79 H +ATOM 31 HE3 LYS A 17 27.459 -13.061 -2.732 1.00 57.01 H +ATOM 32 HE2 LYS A 17 26.180 -11.874 -2.586 1.00 57.01 H +ATOM 33 HZ1 LYS A 17 28.326 -10.902 -2.329 1.00 59.10 H +ATOM 34 HZ2 LYS A 17 28.805 -11.418 -3.822 1.00 59.10 H +ATOM 35 HZ3 LYS A 17 27.606 -10.296 -3.682 1.00 59.10 H +ATOM 36 N ASN A 18 22.534 -13.674 -4.941 1.00 45.87 N +ATOM 37 CA ASN A 18 21.461 -13.558 -3.950 1.00 44.12 C +ATOM 38 C ASN A 18 21.811 -12.503 -2.887 1.00 40.49 C +ATOM 39 O ASN A 18 22.990 -12.349 -2.557 1.00 38.53 O +ATOM 40 CB ASN A 18 21.221 -14.929 -3.273 1.00 45.88 C +ATOM 41 CG ASN A 18 20.663 -16.028 -4.189 1.00 48.93 C +ATOM 42 OD1 ASN A 18 20.711 -15.937 -5.414 1.00 50.57 O +ATOM 43 ND2 ASN A 18 20.140 -17.097 -3.585 1.00 49.83 N +ATOM 44 H ASN A 18 23.043 -14.546 -4.940 1.00 45.87 H +ATOM 45 HA ASN A 18 20.571 -13.264 -4.502 1.00 44.12 H +ATOM 46 HB3 ASN A 18 20.515 -14.801 -2.452 1.00 45.88 H +ATOM 47 HB2 ASN A 18 22.147 -15.292 -2.823 1.00 45.88 H +ATOM 48 HD22 ASN A 18 19.764 -17.854 -4.136 1.00 49.83 H +ATOM 49 HD21 ASN A 18 20.101 -17.148 -2.577 1.00 49.83 H +ATOM 50 N ILE A 19 20.785 -11.816 -2.354 1.00 37.01 N +ATOM 51 CA ILE A 19 20.936 -10.859 -1.254 1.00 33.92 C +ATOM 52 C ILE A 19 21.437 -11.568 0.018 1.00 32.91 C +ATOM 53 O ILE A 19 20.806 -12.523 0.471 1.00 32.02 O +ATOM 54 CB ILE A 19 19.627 -10.064 -0.954 1.00 34.31 C +ATOM 55 CG1 ILE A 19 19.307 -9.139 -2.156 1.00 33.64 C +ATOM 56 CG2 ILE A 19 19.667 -9.262 0.374 1.00 32.90 C +ATOM 57 CD1 ILE A 19 18.136 -8.165 -1.954 1.00 33.56 C +ATOM 58 H ILE A 19 19.841 -11.995 -2.674 1.00 37.01 H +ATOM 59 HA ILE A 19 21.695 -10.142 -1.565 1.00 33.92 H +ATOM 60 HB ILE A 19 18.810 -10.781 -0.877 1.00 34.31 H +ATOM 61 HG13 ILE A 19 19.108 -9.745 -3.041 1.00 33.64 H +ATOM 62 HG12 ILE A 19 20.194 -8.558 -2.400 1.00 33.64 H +ATOM 63 HG21 ILE A 19 18.744 -8.711 0.540 1.00 32.90 H +ATOM 64 HG22 ILE A 19 19.775 -9.903 1.249 1.00 32.90 H +ATOM 65 HG23 ILE A 19 20.487 -8.546 0.385 1.00 32.90 H +ATOM 66 HD11 ILE A 19 17.783 -7.782 -2.911 1.00 33.56 H +ATOM 67 HD12 ILE A 19 17.298 -8.645 -1.453 1.00 33.56 H +ATOM 68 HD13 ILE A 19 18.433 -7.305 -1.357 1.00 33.56 H +ATOM 69 N GLN A 20 22.581 -11.093 0.535 1.00 31.83 N +ATOM 70 CA GLN A 20 23.246 -11.666 1.700 1.00 31.76 C +ATOM 71 C GLN A 20 22.649 -11.100 2.987 1.00 29.83 C +ATOM 72 O GLN A 20 22.845 -9.923 3.283 1.00 30.30 O +ATOM 73 CB GLN A 20 24.758 -11.400 1.625 1.00 32.28 C +ATOM 74 CG GLN A 20 25.436 -12.188 0.492 1.00 35.88 C +ATOM 75 CD GLN A 20 26.959 -12.095 0.565 1.00 37.61 C +ATOM 76 OE1 GLN A 20 27.516 -11.013 0.728 1.00 40.61 O +ATOM 77 NE2 GLN A 20 27.641 -13.231 0.418 1.00 39.78 N +ATOM 78 H GLN A 20 23.027 -10.292 0.113 1.00 31.83 H +ATOM 79 HA GLN A 20 23.099 -12.747 1.693 1.00 31.76 H +ATOM 80 HB3 GLN A 20 25.214 -11.687 2.575 1.00 32.28 H +ATOM 81 HB2 GLN A 20 24.946 -10.332 1.506 1.00 32.28 H +ATOM 82 HG3 GLN A 20 25.101 -11.819 -0.477 1.00 35.88 H +ATOM 83 HG2 GLN A 20 25.137 -13.236 0.546 1.00 35.88 H +ATOM 84 HE22 GLN A 20 28.649 -13.230 0.470 1.00 39.78 H +ATOM 85 HE21 GLN A 20 27.153 -14.107 0.292 1.00 39.78 H +ATOM 86 N VAL A 21 21.934 -11.949 3.729 1.00 27.26 N +ATOM 87 CA VAL A 21 21.259 -11.549 4.953 1.00 26.53 C +ATOM 88 C VAL A 21 22.034 -12.104 6.151 1.00 27.22 C +ATOM 89 O VAL A 21 22.328 -13.298 6.190 1.00 28.15 O +ATOM 90 CB VAL A 21 19.814 -12.090 5.008 1.00 25.02 C +ATOM 91 CG1 VAL A 21 19.068 -11.635 6.274 1.00 25.05 C +ATOM 92 CG2 VAL A 21 19.017 -11.669 3.758 1.00 23.47 C +ATOM 93 H VAL A 21 21.845 -12.920 3.455 1.00 27.26 H +ATOM 94 HA VAL A 21 21.201 -10.464 5.023 1.00 26.53 H +ATOM 95 HB VAL A 21 19.847 -13.180 5.024 1.00 25.02 H +ATOM 96 HG11 VAL A 21 18.077 -12.072 6.286 1.00 25.05 H +ATOM 97 HG12 VAL A 21 19.552 -11.950 7.198 1.00 25.05 H +ATOM 98 HG13 VAL A 21 18.960 -10.550 6.308 1.00 25.05 H +ATOM 99 HG21 VAL A 21 17.985 -12.007 3.810 1.00 23.47 H +ATOM 100 HG22 VAL A 21 19.002 -10.586 3.641 1.00 23.47 H +ATOM 101 HG23 VAL A 21 19.438 -12.094 2.848 1.00 23.47 H +ATOM 102 N VAL A 22 22.328 -11.218 7.110 1.00 26.44 N +ATOM 103 CA VAL A 22 23.018 -11.556 8.348 1.00 27.25 C +ATOM 104 C VAL A 22 22.177 -11.059 9.531 1.00 25.59 C +ATOM 105 O VAL A 22 21.467 -10.064 9.391 1.00 22.16 O +ATOM 106 CB VAL A 22 24.448 -10.936 8.400 1.00 28.72 C +ATOM 107 CG1 VAL A 22 25.230 -11.232 7.107 1.00 32.98 C +ATOM 108 CG2 VAL A 22 24.532 -9.431 8.717 1.00 29.91 C +ATOM 109 H VAL A 22 22.039 -10.253 7.012 1.00 26.44 H +ATOM 110 HA VAL A 22 23.093 -12.636 8.430 1.00 27.25 H +ATOM 111 HB VAL A 22 24.979 -11.448 9.204 1.00 28.72 H +ATOM 112 HG11 VAL A 22 26.256 -10.888 7.188 1.00 32.98 H +ATOM 113 HG12 VAL A 22 25.247 -12.299 6.884 1.00 32.98 H +ATOM 114 HG13 VAL A 22 24.798 -10.723 6.246 1.00 32.98 H +ATOM 115 HG21 VAL A 22 25.564 -9.082 8.681 1.00 29.91 H +ATOM 116 HG22 VAL A 22 23.965 -8.856 7.986 1.00 29.91 H +ATOM 117 HG23 VAL A 22 24.156 -9.193 9.712 1.00 29.91 H +ATOM 118 N VAL A 23 22.269 -11.757 10.672 1.00 24.13 N +ATOM 119 CA VAL A 23 21.580 -11.373 11.905 1.00 23.21 C +ATOM 120 C VAL A 23 22.603 -10.887 12.939 1.00 24.05 C +ATOM 121 O VAL A 23 23.682 -11.468 13.034 1.00 25.40 O +ATOM 122 CB VAL A 23 20.755 -12.554 12.494 1.00 22.95 C +ATOM 123 CG1 VAL A 23 20.241 -12.363 13.940 1.00 24.02 C +ATOM 124 CG2 VAL A 23 19.558 -12.861 11.584 1.00 22.44 C +ATOM 125 H VAL A 23 22.869 -12.569 10.723 1.00 24.13 H +ATOM 126 HA VAL A 23 20.892 -10.560 11.698 1.00 23.21 H +ATOM 127 HB VAL A 23 21.392 -13.440 12.499 1.00 22.95 H +ATOM 128 HG11 VAL A 23 19.594 -13.190 14.235 1.00 24.02 H +ATOM 129 HG12 VAL A 23 21.051 -12.334 14.669 1.00 24.02 H +ATOM 130 HG13 VAL A 23 19.663 -11.444 14.038 1.00 24.02 H +ATOM 131 HG21 VAL A 23 19.017 -13.731 11.946 1.00 22.44 H +ATOM 132 HG22 VAL A 23 18.855 -12.029 11.559 1.00 22.44 H +ATOM 133 HG23 VAL A 23 19.868 -13.067 10.560 1.00 22.44 H +ATOM 134 N ARG A 24 22.228 -9.857 13.714 1.00 23.76 N +ATOM 135 CA ARG A 24 23.009 -9.381 14.849 1.00 24.07 C +ATOM 136 C ARG A 24 22.105 -9.252 16.077 1.00 23.91 C +ATOM 137 O ARG A 24 21.280 -8.343 16.138 1.00 23.91 O +ATOM 138 CB ARG A 24 23.730 -8.063 14.503 1.00 24.65 C +ATOM 139 CG ARG A 24 24.711 -7.627 15.607 1.00 24.28 C +ATOM 140 CD ARG A 24 25.349 -6.260 15.344 1.00 22.93 C +ATOM 141 NE ARG A 24 26.436 -5.996 16.300 1.00 21.81 N +ATOM 142 CZ ARG A 24 27.196 -4.891 16.374 1.00 24.11 C +ATOM 143 NH1 ARG A 24 26.979 -3.833 15.585 1.00 24.49 N +ATOM 144 NH2 ARG A 24 28.200 -4.844 17.256 1.00 25.73 N1+ +ATOM 145 H ARG A 24 21.323 -9.426 13.575 1.00 23.76 H +ATOM 146 HA ARG A 24 23.778 -10.111 15.093 1.00 24.07 H +ATOM 147 HB3 ARG A 24 23.004 -7.272 14.310 1.00 24.65 H +ATOM 148 HB2 ARG A 24 24.290 -8.193 13.576 1.00 24.65 H +ATOM 149 HG3 ARG A 24 25.460 -8.393 15.812 1.00 24.28 H +ATOM 150 HG2 ARG A 24 24.138 -7.528 16.530 1.00 24.28 H +ATOM 151 HD3 ARG A 24 24.600 -5.494 15.551 1.00 22.93 H +ATOM 152 HD2 ARG A 24 25.651 -6.135 14.304 1.00 22.93 H +ATOM 153 HE ARG A 24 26.586 -6.718 16.995 1.00 21.81 H +ATOM 154 HH12 ARG A 24 27.579 -3.019 15.648 1.00 24.49 H +ATOM 155 HH11 ARG A 24 26.195 -3.825 14.944 1.00 24.49 H +ATOM 156 HH22 ARG A 24 28.781 -4.020 17.314 1.00 25.73 H +ATOM 157 HH21 ARG A 24 28.395 -5.632 17.860 1.00 25.73 H +ATOM 158 N CYS A 25 22.320 -10.131 17.063 1.00 22.64 N +ATOM 159 CA CYS A 25 21.715 -10.009 18.383 1.00 24.93 C +ATOM 160 C CYS A 25 22.588 -9.082 19.242 1.00 26.45 C +ATOM 161 O CYS A 25 23.783 -9.344 19.369 1.00 27.13 O +ATOM 162 CB CYS A 25 21.520 -11.392 19.031 1.00 25.80 C +ATOM 163 SG CYS A 25 20.550 -11.265 20.560 1.00 30.42 S +ATOM 164 H CYS A 25 23.024 -10.851 16.953 1.00 22.64 H +ATOM 165 HA CYS A 25 20.730 -9.558 18.277 1.00 24.93 H +ATOM 166 HB3 CYS A 25 22.478 -11.867 19.248 1.00 25.80 H +ATOM 167 HB2 CYS A 25 20.986 -12.055 18.350 1.00 25.80 H +ATOM 168 HG CYS A 25 21.450 -10.556 21.249 1.00 30.42 H +ATOM 169 N ARG A 26 21.984 -8.031 19.822 1.00 25.64 N +ATOM 170 CA ARG A 26 22.656 -7.160 20.793 1.00 26.31 C +ATOM 171 C ARG A 26 22.728 -7.840 22.184 1.00 28.11 C +ATOM 172 O ARG A 26 21.927 -8.735 22.456 1.00 25.72 O +ATOM 173 CB ARG A 26 21.952 -5.782 20.834 1.00 26.30 C +ATOM 174 CG ARG A 26 20.507 -5.752 21.363 1.00 27.32 C +ATOM 175 CD ARG A 26 20.138 -4.352 21.882 1.00 28.22 C +ATOM 176 NE ARG A 26 18.758 -4.277 22.384 1.00 29.36 N +ATOM 177 CZ ARG A 26 18.256 -4.736 23.544 1.00 28.29 C +ATOM 178 NH1 ARG A 26 19.002 -5.395 24.439 1.00 33.40 N +ATOM 179 NH2 ARG A 26 16.966 -4.516 23.822 1.00 32.13 N1+ +ATOM 180 H ARG A 26 20.997 -7.868 19.671 1.00 25.64 H +ATOM 181 HA ARG A 26 23.671 -6.993 20.430 1.00 26.31 H +ATOM 182 HB3 ARG A 26 21.972 -5.339 19.838 1.00 26.30 H +ATOM 183 HB2 ARG A 26 22.541 -5.102 21.444 1.00 26.30 H +ATOM 184 HG3 ARG A 26 20.349 -6.488 22.150 1.00 27.32 H +ATOM 185 HG2 ARG A 26 19.835 -6.033 20.552 1.00 27.32 H +ATOM 186 HD3 ARG A 26 20.220 -3.632 21.067 1.00 28.22 H +ATOM 187 HD2 ARG A 26 20.837 -4.017 22.650 1.00 28.22 H +ATOM 188 HE ARG A 26 18.133 -3.743 21.793 1.00 29.36 H +ATOM 189 HH12 ARG A 26 18.610 -5.668 25.334 1.00 33.40 H +ATOM 190 HH11 ARG A 26 19.982 -5.572 24.262 1.00 33.40 H +ATOM 191 HH22 ARG A 26 16.568 -4.859 24.687 1.00 32.13 H +ATOM 192 HH21 ARG A 26 16.379 -4.009 23.175 1.00 32.13 H +ATOM 193 N PRO A 27 23.652 -7.395 23.064 1.00 31.04 N +ATOM 194 CA PRO A 27 23.677 -7.832 24.471 1.00 34.75 C +ATOM 195 C PRO A 27 22.548 -7.213 25.306 1.00 38.49 C +ATOM 196 O PRO A 27 21.915 -6.248 24.873 1.00 38.86 O +ATOM 197 CB PRO A 27 25.056 -7.353 24.962 1.00 34.27 C +ATOM 198 CG PRO A 27 25.342 -6.111 24.137 1.00 33.61 C +ATOM 199 CD PRO A 27 24.740 -6.460 22.783 1.00 32.04 C +ATOM 200 HA PRO A 27 23.596 -8.916 24.550 1.00 34.75 H +ATOM 201 HB3 PRO A 27 25.810 -8.110 24.748 1.00 34.27 H +ATOM 202 HB2 PRO A 27 25.101 -7.153 26.034 1.00 34.27 H +ATOM 203 HG3 PRO A 27 26.400 -5.854 24.084 1.00 33.61 H +ATOM 204 HG2 PRO A 27 24.810 -5.259 24.564 1.00 33.61 H +ATOM 205 HD2 PRO A 27 24.418 -5.557 22.278 1.00 32.04 H +ATOM 206 HD3 PRO A 27 25.468 -6.964 22.151 1.00 32.04 H +ATOM 207 N PHE A 28 22.361 -7.759 26.519 1.00 42.80 N +ATOM 208 CA PHE A 28 21.550 -7.130 27.558 1.00 45.58 C +ATOM 209 C PHE A 28 22.172 -5.810 28.030 1.00 48.44 C +ATOM 210 O PHE A 28 23.350 -5.792 28.395 1.00 50.16 O +ATOM 211 CB PHE A 28 21.358 -8.084 28.755 1.00 46.72 C +ATOM 212 CG PHE A 28 20.412 -9.250 28.530 1.00 46.51 C +ATOM 213 CD1 PHE A 28 20.782 -10.554 28.922 1.00 48.45 C +ATOM 214 CD2 PHE A 28 19.106 -9.029 28.045 1.00 45.93 C +ATOM 215 CE1 PHE A 28 19.877 -11.597 28.786 1.00 49.91 C +ATOM 216 CE2 PHE A 28 18.214 -10.080 27.926 1.00 45.72 C +ATOM 217 CZ PHE A 28 18.601 -11.357 28.293 1.00 47.71 C +ATOM 218 H PHE A 28 22.906 -8.560 26.800 1.00 42.80 H +ATOM 219 HA PHE A 28 20.582 -6.909 27.113 1.00 45.58 H +ATOM 220 HB3 PHE A 28 20.972 -7.535 29.615 1.00 46.72 H +ATOM 221 HB2 PHE A 28 22.331 -8.471 29.061 1.00 46.72 H +ATOM 222 HD1 PHE A 28 21.763 -10.747 29.330 1.00 48.45 H +ATOM 223 HD2 PHE A 28 18.780 -8.044 27.770 1.00 45.93 H +ATOM 224 HE1 PHE A 28 20.159 -12.596 29.085 1.00 49.91 H +ATOM 225 HE2 PHE A 28 17.217 -9.903 27.555 1.00 45.72 H +ATOM 226 HZ PHE A 28 17.891 -12.159 28.207 1.00 47.71 H +ATOM 227 N ASN A 29 21.356 -4.744 28.045 1.00 50.46 N +ATOM 228 CA ASN A 29 21.730 -3.436 28.584 1.00 53.78 C +ATOM 229 C ASN A 29 21.845 -3.467 30.123 1.00 55.58 C +ATOM 230 O ASN A 29 21.491 -4.460 30.761 1.00 55.96 O +ATOM 231 CB ASN A 29 20.788 -2.331 28.027 1.00 53.62 C +ATOM 232 CG ASN A 29 19.304 -2.428 28.409 1.00 54.79 C +ATOM 233 OD1 ASN A 29 18.962 -2.562 29.578 1.00 53.72 O +ATOM 234 ND2 ASN A 29 18.409 -2.325 27.424 1.00 53.06 N +ATOM 235 H ASN A 29 20.391 -4.853 27.754 1.00 50.46 H +ATOM 236 HA ASN A 29 22.729 -3.210 28.207 1.00 53.78 H +ATOM 237 HB3 ASN A 29 20.871 -2.323 26.939 1.00 53.62 H +ATOM 238 HB2 ASN A 29 21.142 -1.352 28.351 1.00 53.62 H +ATOM 239 HD22 ASN A 29 17.423 -2.390 27.631 1.00 53.06 H +ATOM 240 HD21 ASN A 29 18.707 -2.207 26.467 1.00 53.06 H +ATOM 241 N LEU A 30 22.341 -2.359 30.693 1.00 57.56 N +ATOM 242 CA LEU A 30 22.530 -2.164 32.133 1.00 59.64 C +ATOM 243 C LEU A 30 21.217 -2.299 32.935 1.00 60.88 C +ATOM 244 O LEU A 30 21.245 -2.847 34.034 1.00 62.21 O +ATOM 245 CB LEU A 30 23.193 -0.788 32.386 1.00 60.12 C +ATOM 246 CG LEU A 30 24.697 -0.689 32.028 1.00 60.89 C +ATOM 247 CD1 LEU A 30 25.005 -0.909 30.531 1.00 60.86 C +ATOM 248 CD2 LEU A 30 25.298 0.642 32.525 1.00 62.34 C +ATOM 249 H LEU A 30 22.613 -1.583 30.107 1.00 57.56 H +ATOM 250 HA LEU A 30 23.203 -2.946 32.490 1.00 59.64 H +ATOM 251 HB3 LEU A 30 23.099 -0.560 33.450 1.00 60.12 H +ATOM 252 HB2 LEU A 30 22.635 -0.005 31.869 1.00 60.12 H +ATOM 253 HG LEU A 30 25.206 -1.469 32.590 1.00 60.89 H +ATOM 254 HD11 LEU A 30 25.918 -0.401 30.221 1.00 60.86 H +ATOM 255 HD12 LEU A 30 25.141 -1.966 30.307 1.00 60.86 H +ATOM 256 HD13 LEU A 30 24.200 -0.535 29.898 1.00 60.86 H +ATOM 257 HD21 LEU A 30 26.157 0.462 33.173 1.00 62.34 H +ATOM 258 HD22 LEU A 30 25.636 1.279 31.708 1.00 62.34 H +ATOM 259 HD23 LEU A 30 24.580 1.227 33.101 1.00 62.34 H +ATOM 260 N ALA A 31 20.094 -1.847 32.350 1.00 61.49 N +ATOM 261 CA ALA A 31 18.746 -1.937 32.915 1.00 61.47 C +ATOM 262 C ALA A 31 18.064 -3.316 32.763 1.00 60.67 C +ATOM 263 O ALA A 31 16.956 -3.472 33.275 1.00 59.44 O +ATOM 264 CB ALA A 31 17.889 -0.813 32.311 1.00 63.13 C +ATOM 265 H ALA A 31 20.149 -1.452 31.421 1.00 61.49 H +ATOM 266 HA ALA A 31 18.815 -1.746 33.986 1.00 61.47 H +ATOM 267 HB1 ALA A 31 16.896 -0.782 32.762 1.00 63.13 H +ATOM 268 HB2 ALA A 31 18.348 0.162 32.477 1.00 63.13 H +ATOM 269 HB3 ALA A 31 17.755 -0.936 31.236 1.00 63.13 H +ATOM 270 N GLU A 32 18.716 -4.284 32.093 1.00 60.89 N +ATOM 271 CA GLU A 32 18.238 -5.659 31.908 1.00 61.52 C +ATOM 272 C GLU A 32 19.019 -6.665 32.769 1.00 61.89 C +ATOM 273 O GLU A 32 18.408 -7.600 33.286 1.00 62.53 O +ATOM 274 CB GLU A 32 18.311 -6.042 30.413 1.00 60.85 C +ATOM 275 CG GLU A 32 17.153 -5.444 29.581 1.00 60.97 C +ATOM 276 CD GLU A 32 17.285 -5.627 28.059 1.00 60.90 C +ATOM 277 OE1 GLU A 32 18.420 -5.548 27.545 1.00 59.14 O +ATOM 278 OE2 GLU A 32 16.237 -5.813 27.404 1.00 59.59 O1- +ATOM 279 H GLU A 32 19.606 -4.068 31.665 1.00 60.89 H +ATOM 280 HA GLU A 32 17.194 -5.739 32.219 1.00 61.52 H +ATOM 281 HB3 GLU A 32 18.307 -7.127 30.297 1.00 60.85 H +ATOM 282 HB2 GLU A 32 19.269 -5.707 30.016 1.00 60.85 H +ATOM 283 HG3 GLU A 32 17.065 -4.377 29.778 1.00 60.97 H +ATOM 284 HG2 GLU A 32 16.214 -5.886 29.918 1.00 60.97 H +ATOM 285 N ARG A 33 20.340 -6.462 32.926 1.00 62.13 N +ATOM 286 CA ARG A 33 21.209 -7.335 33.724 1.00 62.76 C +ATOM 287 C ARG A 33 20.979 -7.224 35.241 1.00 63.12 C +ATOM 288 O ARG A 33 21.171 -8.225 35.930 1.00 62.75 O +ATOM 289 CB ARG A 33 22.684 -7.061 33.394 1.00 62.27 C +ATOM 290 CG ARG A 33 23.081 -7.461 31.963 1.00 62.64 C +ATOM 291 CD ARG A 33 24.594 -7.388 31.686 1.00 63.34 C +ATOM 292 NE ARG A 33 25.108 -6.008 31.607 1.00 64.48 N +ATOM 293 CZ ARG A 33 25.614 -5.231 32.585 1.00 65.42 C +ATOM 294 NH1 ARG A 33 25.669 -5.606 33.872 1.00 65.97 N +ATOM 295 NH2 ARG A 33 26.099 -4.031 32.252 1.00 64.71 N1+ +ATOM 296 H ARG A 33 20.784 -5.681 32.463 1.00 62.13 H +ATOM 297 HA ARG A 33 20.991 -8.369 33.450 1.00 62.76 H +ATOM 298 HB3 ARG A 33 23.312 -7.627 34.084 1.00 62.27 H +ATOM 299 HB2 ARG A 33 22.902 -6.006 33.567 1.00 62.27 H +ATOM 300 HG3 ARG A 33 22.571 -6.784 31.279 1.00 62.64 H +ATOM 301 HG2 ARG A 33 22.712 -8.456 31.710 1.00 62.64 H +ATOM 302 HD3 ARG A 33 24.844 -7.946 30.784 1.00 63.34 H +ATOM 303 HD2 ARG A 33 25.130 -7.890 32.492 1.00 63.34 H +ATOM 304 HE ARG A 33 25.048 -5.606 30.681 1.00 64.48 H +ATOM 305 HH12 ARG A 33 26.068 -4.999 34.573 1.00 65.97 H +ATOM 306 HH11 ARG A 33 25.321 -6.515 34.144 1.00 65.97 H +ATOM 307 HH22 ARG A 33 26.501 -3.428 32.955 1.00 64.71 H +ATOM 308 HH21 ARG A 33 26.088 -3.724 31.290 1.00 64.71 H +ATOM 309 N LYS A 34 20.542 -6.049 35.732 1.00 63.45 N +ATOM 310 CA LYS A 34 20.125 -5.846 37.126 1.00 64.03 C +ATOM 311 C LYS A 34 18.891 -6.680 37.512 1.00 64.60 C +ATOM 312 O LYS A 34 18.813 -7.142 38.650 1.00 65.69 O +ATOM 313 CB LYS A 34 19.824 -4.358 37.376 1.00 63.62 C +ATOM 314 CG LYS A 34 21.065 -3.453 37.415 1.00 64.63 C +ATOM 315 CD LYS A 34 20.789 -2.005 37.873 1.00 64.91 C +ATOM 316 CE LYS A 34 19.717 -1.227 37.078 1.00 65.86 C +ATOM 317 NZ LYS A 34 18.341 -1.488 37.545 1.00 65.56 N1+ +ATOM 318 H LYS A 34 20.419 -5.265 35.107 1.00 63.45 H +ATOM 319 HA LYS A 34 20.950 -6.153 37.772 1.00 64.03 H +ATOM 320 HB3 LYS A 34 19.325 -4.259 38.343 1.00 63.62 H +ATOM 321 HB2 LYS A 34 19.117 -4.007 36.623 1.00 63.62 H +ATOM 322 HG3 LYS A 34 21.548 -3.445 36.441 1.00 64.63 H +ATOM 323 HG2 LYS A 34 21.798 -3.890 38.094 1.00 64.63 H +ATOM 324 HD3 LYS A 34 21.726 -1.452 37.797 1.00 64.91 H +ATOM 325 HD2 LYS A 34 20.549 -2.003 38.937 1.00 64.91 H +ATOM 326 HE3 LYS A 34 19.803 -1.439 36.014 1.00 65.86 H +ATOM 327 HE2 LYS A 34 19.894 -0.158 37.197 1.00 65.86 H +ATOM 328 HZ1 LYS A 34 18.263 -1.240 38.522 1.00 65.56 H +ATOM 329 HZ2 LYS A 34 17.690 -0.934 37.006 1.00 65.56 H +ATOM 330 HZ3 LYS A 34 18.123 -2.467 37.430 1.00 65.56 H +ATOM 331 N ALA A 35 17.971 -6.869 36.550 1.00 64.26 N +ATOM 332 CA ALA A 35 16.790 -7.719 36.680 1.00 64.31 C +ATOM 333 C ALA A 35 17.092 -9.217 36.489 1.00 64.22 C +ATOM 334 O ALA A 35 16.199 -10.028 36.731 1.00 63.88 O +ATOM 335 CB ALA A 35 15.740 -7.245 35.661 1.00 63.53 C +ATOM 336 H ALA A 35 18.120 -6.462 35.638 1.00 64.26 H +ATOM 337 HA ALA A 35 16.372 -7.591 37.681 1.00 64.31 H +ATOM 338 HB1 ALA A 35 14.813 -7.812 35.755 1.00 63.53 H +ATOM 339 HB2 ALA A 35 15.494 -6.194 35.812 1.00 63.53 H +ATOM 340 HB3 ALA A 35 16.093 -7.359 34.636 1.00 63.53 H +ATOM 341 N SER A 36 18.322 -9.555 36.050 1.00 64.97 N +ATOM 342 CA SER A 36 18.800 -10.899 35.709 1.00 64.87 C +ATOM 343 C SER A 36 17.929 -11.548 34.618 1.00 64.00 C +ATOM 344 O SER A 36 17.423 -12.656 34.806 1.00 64.70 O +ATOM 345 CB SER A 36 18.947 -11.771 36.979 1.00 65.13 C +ATOM 346 OG SER A 36 20.030 -11.309 37.760 1.00 65.33 O +ATOM 347 H SER A 36 18.995 -8.816 35.901 1.00 64.97 H +ATOM 348 HA SER A 36 19.789 -10.778 35.263 1.00 64.87 H +ATOM 349 HB3 SER A 36 19.168 -12.806 36.714 1.00 65.13 H +ATOM 350 HB2 SER A 36 18.037 -11.784 37.578 1.00 65.13 H +ATOM 351 HG SER A 36 19.806 -10.439 38.101 1.00 65.33 H +ATOM 352 N ALA A 37 17.737 -10.805 33.513 1.00 62.61 N +ATOM 353 CA ALA A 37 16.912 -11.194 32.371 1.00 60.97 C +ATOM 354 C ALA A 37 17.411 -12.488 31.710 1.00 59.83 C +ATOM 355 O ALA A 37 18.604 -12.606 31.429 1.00 59.91 O +ATOM 356 CB ALA A 37 16.888 -10.037 31.358 1.00 60.54 C +ATOM 357 H ALA A 37 18.169 -9.893 33.451 1.00 62.61 H +ATOM 358 HA ALA A 37 15.895 -11.351 32.736 1.00 60.97 H +ATOM 359 HB1 ALA A 37 16.288 -10.288 30.483 1.00 60.54 H +ATOM 360 HB2 ALA A 37 16.458 -9.138 31.800 1.00 60.54 H +ATOM 361 HB3 ALA A 37 17.892 -9.787 31.012 1.00 60.54 H +ATOM 362 N HIS A 38 16.481 -13.426 31.476 1.00 58.07 N +ATOM 363 CA HIS A 38 16.738 -14.670 30.753 1.00 56.37 C +ATOM 364 C HIS A 38 16.643 -14.400 29.245 1.00 53.14 C +ATOM 365 O HIS A 38 15.660 -13.812 28.788 1.00 52.97 O +ATOM 366 CB HIS A 38 15.751 -15.767 31.212 1.00 57.37 C +ATOM 367 CG HIS A 38 14.291 -15.485 30.947 1.00 58.33 C +ATOM 368 ND1 HIS A 38 13.585 -16.074 29.891 1.00 58.82 N +ATOM 369 CD2 HIS A 38 13.450 -14.624 31.621 1.00 58.28 C +ATOM 370 CE1 HIS A 38 12.377 -15.531 29.957 1.00 58.75 C +ATOM 371 NE2 HIS A 38 12.241 -14.664 30.957 1.00 57.35 N +ATOM 372 H HIS A 38 15.522 -13.252 31.738 1.00 58.07 H +ATOM 373 HA HIS A 38 17.746 -15.016 30.992 1.00 56.37 H +ATOM 374 HB3 HIS A 38 15.872 -15.941 32.282 1.00 57.37 H +ATOM 375 HB2 HIS A 38 16.010 -16.711 30.730 1.00 57.37 H +ATOM 376 HD2 HIS A 38 13.617 -13.990 32.479 1.00 58.28 H +ATOM 377 HE1 HIS A 38 11.582 -15.745 29.259 1.00 58.75 H +ATOM 378 HE2 HIS A 38 11.414 -14.125 31.176 1.00 57.35 H +ATOM 379 N SER A 39 17.675 -14.828 28.504 1.00 49.89 N +ATOM 380 CA SER A 39 17.704 -14.716 27.050 1.00 45.41 C +ATOM 381 C SER A 39 16.875 -15.843 26.426 1.00 41.77 C +ATOM 382 O SER A 39 17.040 -17.004 26.804 1.00 42.08 O +ATOM 383 CB SER A 39 19.161 -14.739 26.551 1.00 45.19 C +ATOM 384 OG SER A 39 19.209 -14.520 25.156 1.00 47.29 O +ATOM 385 H SER A 39 18.452 -15.303 28.940 1.00 49.89 H +ATOM 386 HA SER A 39 17.269 -13.757 26.762 1.00 45.41 H +ATOM 387 HB3 SER A 39 19.642 -15.690 26.781 1.00 45.19 H +ATOM 388 HB2 SER A 39 19.745 -13.958 27.038 1.00 45.19 H +ATOM 389 HG SER A 39 20.064 -14.807 24.823 1.00 47.29 H +ATOM 390 N ILE A 40 16.029 -15.469 25.458 1.00 37.57 N +ATOM 391 CA ILE A 40 15.319 -16.412 24.602 1.00 34.91 C +ATOM 392 C ILE A 40 16.072 -16.669 23.282 1.00 33.66 C +ATOM 393 O ILE A 40 15.690 -17.599 22.583 1.00 33.63 O +ATOM 394 CB ILE A 40 13.869 -15.941 24.296 1.00 35.48 C +ATOM 395 CG1 ILE A 40 13.760 -14.583 23.564 1.00 33.76 C +ATOM 396 CG2 ILE A 40 13.027 -15.957 25.585 1.00 34.54 C +ATOM 397 CD1 ILE A 40 12.395 -14.342 22.904 1.00 35.52 C +ATOM 398 H ILE A 40 15.953 -14.491 25.210 1.00 37.57 H +ATOM 399 HA ILE A 40 15.246 -17.381 25.101 1.00 34.91 H +ATOM 400 HB ILE A 40 13.424 -16.682 23.630 1.00 35.48 H +ATOM 401 HG13 ILE A 40 14.516 -14.505 22.786 1.00 33.76 H +ATOM 402 HG12 ILE A 40 13.969 -13.775 24.262 1.00 33.76 H +ATOM 403 HG21 ILE A 40 11.981 -15.719 25.397 1.00 34.54 H +ATOM 404 HG22 ILE A 40 13.053 -16.939 26.055 1.00 34.54 H +ATOM 405 HG23 ILE A 40 13.409 -15.238 26.309 1.00 34.54 H +ATOM 406 HD11 ILE A 40 12.030 -13.338 23.116 1.00 35.52 H +ATOM 407 HD12 ILE A 40 12.463 -14.437 21.821 1.00 35.52 H +ATOM 408 HD13 ILE A 40 11.639 -15.044 23.249 1.00 35.52 H +ATOM 409 N VAL A 41 17.127 -15.892 22.973 1.00 32.34 N +ATOM 410 CA VAL A 41 17.910 -16.023 21.744 1.00 33.13 C +ATOM 411 C VAL A 41 19.268 -16.693 22.034 1.00 33.37 C +ATOM 412 O VAL A 41 20.004 -16.236 22.908 1.00 33.03 O +ATOM 413 CB VAL A 41 18.170 -14.635 21.087 1.00 31.02 C +ATOM 414 CG1 VAL A 41 19.098 -14.683 19.855 1.00 30.01 C +ATOM 415 CG2 VAL A 41 16.850 -13.950 20.688 1.00 32.15 C +ATOM 416 H VAL A 41 17.427 -15.172 23.616 1.00 32.34 H +ATOM 417 HA VAL A 41 17.365 -16.627 21.017 1.00 33.13 H +ATOM 418 HB VAL A 41 18.658 -13.993 21.822 1.00 31.02 H +ATOM 419 HG11 VAL A 41 19.158 -13.711 19.368 1.00 30.01 H +ATOM 420 HG12 VAL A 41 20.120 -14.963 20.111 1.00 30.01 H +ATOM 421 HG13 VAL A 41 18.727 -15.398 19.122 1.00 30.01 H +ATOM 422 HG21 VAL A 41 17.034 -13.002 20.180 1.00 32.15 H +ATOM 423 HG22 VAL A 41 16.264 -14.575 20.016 1.00 32.15 H +ATOM 424 HG23 VAL A 41 16.235 -13.727 21.558 1.00 32.15 H +ATOM 425 N GLU A 42 19.589 -17.725 21.239 1.00 34.68 N +ATOM 426 CA GLU A 42 20.917 -18.330 21.142 1.00 37.62 C +ATOM 427 C GLU A 42 21.416 -18.169 19.704 1.00 37.62 C +ATOM 428 O GLU A 42 20.675 -18.465 18.768 1.00 37.32 O +ATOM 429 CB GLU A 42 20.870 -19.823 21.518 1.00 39.30 C +ATOM 430 CG GLU A 42 20.636 -20.073 23.023 1.00 44.83 C +ATOM 431 CD GLU A 42 20.549 -21.556 23.429 1.00 48.30 C +ATOM 432 OE1 GLU A 42 20.972 -22.431 22.640 1.00 49.42 O +ATOM 433 OE2 GLU A 42 20.044 -21.792 24.548 1.00 47.07 O1- +ATOM 434 H GLU A 42 18.920 -18.039 20.547 1.00 34.68 H +ATOM 435 HA GLU A 42 21.621 -17.826 21.807 1.00 37.62 H +ATOM 436 HB3 GLU A 42 21.808 -20.295 21.217 1.00 39.30 H +ATOM 437 HB2 GLU A 42 20.085 -20.318 20.944 1.00 39.30 H +ATOM 438 HG3 GLU A 42 19.726 -19.565 23.342 1.00 44.83 H +ATOM 439 HG2 GLU A 42 21.448 -19.620 23.592 1.00 44.83 H +ATOM 440 N CYS A 43 22.673 -17.727 19.570 1.00 37.12 N +ATOM 441 CA CYS A 43 23.362 -17.537 18.297 1.00 38.66 C +ATOM 442 C CYS A 43 24.501 -18.560 18.197 1.00 40.09 C +ATOM 443 O CYS A 43 25.208 -18.786 19.180 1.00 40.18 O +ATOM 444 CB CYS A 43 23.930 -16.109 18.189 1.00 37.97 C +ATOM 445 SG CYS A 43 22.581 -14.923 17.915 1.00 39.98 S +ATOM 446 H CYS A 43 23.223 -17.540 20.396 1.00 37.12 H +ATOM 447 HA CYS A 43 22.683 -17.703 17.458 1.00 38.66 H +ATOM 448 HB3 CYS A 43 24.633 -16.027 17.360 1.00 37.97 H +ATOM 449 HB2 CYS A 43 24.478 -15.833 19.091 1.00 37.97 H +ATOM 450 HG CYS A 43 22.271 -15.343 16.686 1.00 39.98 H +ATOM 451 N ASP A 44 24.675 -19.122 16.992 1.00 39.18 N +ATOM 452 CA ASP A 44 25.745 -20.054 16.646 1.00 39.68 C +ATOM 453 C ASP A 44 26.288 -19.598 15.274 1.00 37.75 C +ATOM 454 O ASP A 44 25.747 -20.029 14.256 1.00 34.98 O +ATOM 455 CB ASP A 44 25.243 -21.526 16.689 1.00 42.51 C +ATOM 456 CG ASP A 44 26.304 -22.640 16.552 1.00 45.22 C +ATOM 457 OD1 ASP A 44 27.392 -22.396 15.984 1.00 46.28 O +ATOM 458 OD2 ASP A 44 25.957 -23.782 16.927 1.00 48.98 O1- +ATOM 459 H ASP A 44 24.035 -18.897 16.240 1.00 39.18 H +ATOM 460 HA ASP A 44 26.544 -19.997 17.385 1.00 39.68 H +ATOM 461 HB3 ASP A 44 24.480 -21.676 15.923 1.00 42.51 H +ATOM 462 HB2 ASP A 44 24.713 -21.677 17.631 1.00 42.51 H +ATOM 463 N PRO A 45 27.326 -18.725 15.265 1.00 37.21 N +ATOM 464 CA PRO A 45 27.967 -18.229 14.028 1.00 38.23 C +ATOM 465 C PRO A 45 28.553 -19.293 13.082 1.00 39.60 C +ATOM 466 O PRO A 45 28.496 -19.092 11.869 1.00 38.37 O +ATOM 467 CB PRO A 45 29.075 -17.287 14.534 1.00 37.82 C +ATOM 468 CG PRO A 45 28.604 -16.837 15.904 1.00 36.47 C +ATOM 469 CD PRO A 45 27.909 -18.077 16.443 1.00 37.30 C +ATOM 470 HA PRO A 45 27.216 -17.646 13.490 1.00 38.23 H +ATOM 471 HB3 PRO A 45 29.255 -16.449 13.862 1.00 37.82 H +ATOM 472 HB2 PRO A 45 30.020 -17.823 14.645 1.00 37.82 H +ATOM 473 HG3 PRO A 45 27.875 -16.033 15.797 1.00 36.47 H +ATOM 474 HG2 PRO A 45 29.409 -16.478 16.545 1.00 36.47 H +ATOM 475 HD2 PRO A 45 28.630 -18.758 16.898 1.00 37.30 H +ATOM 476 HD3 PRO A 45 27.177 -17.794 17.199 1.00 37.30 H +ATOM 477 N VAL A 46 29.099 -20.388 13.643 1.00 40.68 N +ATOM 478 CA VAL A 46 29.722 -21.487 12.894 1.00 42.73 C +ATOM 479 C VAL A 46 28.687 -22.267 12.062 1.00 44.14 C +ATOM 480 O VAL A 46 28.940 -22.553 10.892 1.00 44.76 O +ATOM 481 CB VAL A 46 30.458 -22.486 13.837 1.00 45.34 C +ATOM 482 CG1 VAL A 46 31.100 -23.688 13.109 1.00 45.35 C +ATOM 483 CG2 VAL A 46 31.527 -21.776 14.687 1.00 45.25 C +ATOM 484 H VAL A 46 29.087 -20.492 14.648 1.00 40.68 H +ATOM 485 HA VAL A 46 30.452 -21.054 12.208 1.00 42.73 H +ATOM 486 HB VAL A 46 29.730 -22.898 14.537 1.00 45.34 H +ATOM 487 HG11 VAL A 46 31.679 -24.301 13.799 1.00 45.35 H +ATOM 488 HG12 VAL A 46 30.355 -24.347 12.661 1.00 45.35 H +ATOM 489 HG13 VAL A 46 31.773 -23.357 12.318 1.00 45.35 H +ATOM 490 HG21 VAL A 46 32.043 -22.479 15.342 1.00 45.25 H +ATOM 491 HG22 VAL A 46 32.277 -21.296 14.058 1.00 45.25 H +ATOM 492 HG23 VAL A 46 31.090 -21.009 15.327 1.00 45.25 H +ATOM 493 N ARG A 47 27.526 -22.541 12.678 1.00 43.50 N +ATOM 494 CA ARG A 47 26.360 -23.145 12.036 1.00 44.40 C +ATOM 495 C ARG A 47 25.573 -22.138 11.171 1.00 43.29 C +ATOM 496 O ARG A 47 24.765 -22.558 10.344 1.00 42.55 O +ATOM 497 CB ARG A 47 25.470 -23.732 13.148 1.00 46.46 C +ATOM 498 CG ARG A 47 24.634 -24.946 12.709 1.00 51.87 C +ATOM 499 CD ARG A 47 25.373 -26.293 12.807 1.00 55.57 C +ATOM 500 NE ARG A 47 25.573 -26.702 14.211 1.00 59.35 N +ATOM 501 CZ ARG A 47 26.228 -27.780 14.675 1.00 61.63 C +ATOM 502 NH1 ARG A 47 26.815 -28.666 13.855 1.00 62.28 N +ATOM 503 NH2 ARG A 47 26.297 -27.967 15.999 1.00 61.37 N1+ +ATOM 504 H ARG A 47 27.410 -22.283 13.650 1.00 43.50 H +ATOM 505 HA ARG A 47 26.716 -23.954 11.395 1.00 44.40 H +ATOM 506 HB3 ARG A 47 24.822 -22.955 13.557 1.00 46.46 H +ATOM 507 HB2 ARG A 47 26.096 -24.040 13.985 1.00 46.46 H +ATOM 508 HG3 ARG A 47 24.162 -24.818 11.735 1.00 51.87 H +ATOM 509 HG2 ARG A 47 23.812 -24.987 13.422 1.00 51.87 H +ATOM 510 HD3 ARG A 47 26.382 -26.156 12.417 1.00 55.57 H +ATOM 511 HD2 ARG A 47 24.903 -27.063 12.194 1.00 55.57 H +ATOM 512 HE ARG A 47 25.181 -26.066 14.893 1.00 59.35 H +ATOM 513 HH12 ARG A 47 27.304 -29.468 14.225 1.00 62.28 H +ATOM 514 HH11 ARG A 47 26.768 -28.530 12.856 1.00 62.28 H +ATOM 515 HH22 ARG A 47 26.780 -28.765 16.383 1.00 61.37 H +ATOM 516 HH21 ARG A 47 25.881 -27.292 16.627 1.00 61.37 H +ATOM 517 N LYS A 48 25.816 -20.833 11.401 1.00 42.41 N +ATOM 518 CA LYS A 48 25.125 -19.669 10.841 1.00 40.29 C +ATOM 519 C LYS A 48 23.639 -19.630 11.243 1.00 39.93 C +ATOM 520 O LYS A 48 22.806 -19.196 10.448 1.00 39.37 O +ATOM 521 CB LYS A 48 25.321 -19.575 9.313 1.00 41.78 C +ATOM 522 CG LYS A 48 26.783 -19.476 8.864 1.00 43.17 C +ATOM 523 CD LYS A 48 26.912 -19.576 7.334 1.00 45.52 C +ATOM 524 CE LYS A 48 28.298 -19.179 6.800 1.00 47.46 C +ATOM 525 NZ LYS A 48 29.365 -20.080 7.271 1.00 50.93 N1+ +ATOM 526 H LYS A 48 26.512 -20.608 12.099 1.00 42.41 H +ATOM 527 HA LYS A 48 25.585 -18.790 11.295 1.00 40.29 H +ATOM 528 HB3 LYS A 48 24.817 -18.679 8.955 1.00 41.78 H +ATOM 529 HB2 LYS A 48 24.841 -20.420 8.818 1.00 41.78 H +ATOM 530 HG3 LYS A 48 27.375 -20.263 9.331 1.00 43.17 H +ATOM 531 HG2 LYS A 48 27.198 -18.530 9.212 1.00 43.17 H +ATOM 532 HD3 LYS A 48 26.155 -18.950 6.864 1.00 45.52 H +ATOM 533 HD2 LYS A 48 26.677 -20.594 7.020 1.00 45.52 H +ATOM 534 HE3 LYS A 48 28.544 -18.162 7.107 1.00 47.46 H +ATOM 535 HE2 LYS A 48 28.291 -19.189 5.709 1.00 47.46 H +ATOM 536 HZ1 LYS A 48 30.254 -19.777 6.901 1.00 50.93 H +ATOM 537 HZ2 LYS A 48 29.397 -20.063 8.281 1.00 50.93 H +ATOM 538 HZ3 LYS A 48 29.173 -21.022 6.959 1.00 50.93 H +ATOM 539 N GLU A 49 23.340 -20.092 12.468 1.00 38.53 N +ATOM 540 CA GLU A 49 21.989 -20.229 12.994 1.00 39.11 C +ATOM 541 C GLU A 49 21.716 -19.262 14.143 1.00 37.38 C +ATOM 542 O GLU A 49 22.619 -18.913 14.903 1.00 35.68 O +ATOM 543 CB GLU A 49 21.744 -21.672 13.470 1.00 41.64 C +ATOM 544 CG GLU A 49 21.632 -22.677 12.306 1.00 47.78 C +ATOM 545 CD GLU A 49 21.267 -24.114 12.711 1.00 51.12 C +ATOM 546 OE1 GLU A 49 21.072 -24.382 13.918 1.00 50.60 O +ATOM 547 OE2 GLU A 49 21.203 -24.946 11.779 1.00 52.69 O1- +ATOM 548 H GLU A 49 24.088 -20.390 13.081 1.00 38.53 H +ATOM 549 HA GLU A 49 21.275 -20.012 12.205 1.00 39.11 H +ATOM 550 HB3 GLU A 49 20.830 -21.710 14.066 1.00 41.64 H +ATOM 551 HB2 GLU A 49 22.553 -21.979 14.136 1.00 41.64 H +ATOM 552 HG3 GLU A 49 22.569 -22.702 11.752 1.00 47.78 H +ATOM 553 HG2 GLU A 49 20.871 -22.325 11.608 1.00 47.78 H +ATOM 554 N VAL A 50 20.431 -18.915 14.258 1.00 35.62 N +ATOM 555 CA VAL A 50 19.838 -18.205 15.377 1.00 35.40 C +ATOM 556 C VAL A 50 18.571 -18.974 15.785 1.00 35.75 C +ATOM 557 O VAL A 50 17.700 -19.221 14.950 1.00 34.76 O +ATOM 558 CB VAL A 50 19.523 -16.727 15.021 1.00 35.70 C +ATOM 559 CG1 VAL A 50 18.625 -16.548 13.786 1.00 37.29 C +ATOM 560 CG2 VAL A 50 18.952 -15.935 16.210 1.00 33.58 C +ATOM 561 H VAL A 50 19.773 -19.247 13.564 1.00 35.62 H +ATOM 562 HA VAL A 50 20.536 -18.211 16.215 1.00 35.40 H +ATOM 563 HB VAL A 50 20.481 -16.267 14.772 1.00 35.70 H +ATOM 564 HG11 VAL A 50 18.651 -15.512 13.455 1.00 37.29 H +ATOM 565 HG12 VAL A 50 18.971 -17.152 12.949 1.00 37.29 H +ATOM 566 HG13 VAL A 50 17.586 -16.808 13.984 1.00 37.29 H +ATOM 567 HG21 VAL A 50 18.835 -14.883 15.954 1.00 33.58 H +ATOM 568 HG22 VAL A 50 17.976 -16.305 16.524 1.00 33.58 H +ATOM 569 HG23 VAL A 50 19.625 -15.992 17.065 1.00 33.58 H +ATOM 570 N SER A 51 18.531 -19.373 17.063 1.00 34.36 N +ATOM 571 CA SER A 51 17.468 -20.172 17.656 1.00 34.46 C +ATOM 572 C SER A 51 16.752 -19.323 18.711 1.00 35.79 C +ATOM 573 O SER A 51 17.421 -18.742 19.564 1.00 35.89 O +ATOM 574 CB SER A 51 18.094 -21.444 18.258 1.00 37.01 C +ATOM 575 OG SER A 51 17.089 -22.332 18.698 1.00 39.31 O +ATOM 576 H SER A 51 19.288 -19.117 17.685 1.00 34.36 H +ATOM 577 HA SER A 51 16.753 -20.474 16.893 1.00 34.46 H +ATOM 578 HB3 SER A 51 18.754 -21.205 19.092 1.00 37.01 H +ATOM 579 HB2 SER A 51 18.702 -21.958 17.512 1.00 37.01 H +ATOM 580 HG SER A 51 16.696 -22.752 17.929 1.00 39.31 H +ATOM 581 N VAL A 52 15.415 -19.273 18.632 1.00 34.84 N +ATOM 582 CA VAL A 52 14.570 -18.466 19.509 1.00 36.07 C +ATOM 583 C VAL A 52 13.629 -19.387 20.295 1.00 36.69 C +ATOM 584 O VAL A 52 12.938 -20.195 19.682 1.00 39.27 O +ATOM 585 CB VAL A 52 13.694 -17.470 18.700 1.00 35.47 C +ATOM 586 CG1 VAL A 52 12.754 -16.624 19.585 1.00 35.27 C +ATOM 587 CG2 VAL A 52 14.562 -16.535 17.847 1.00 35.83 C +ATOM 588 H VAL A 52 14.937 -19.779 17.897 1.00 34.84 H +ATOM 589 HA VAL A 52 15.179 -17.887 20.200 1.00 36.07 H +ATOM 590 HB VAL A 52 13.066 -18.031 18.006 1.00 35.47 H +ATOM 591 HG11 VAL A 52 12.254 -15.847 19.008 1.00 35.27 H +ATOM 592 HG12 VAL A 52 11.970 -17.226 20.044 1.00 35.27 H +ATOM 593 HG13 VAL A 52 13.310 -16.132 20.384 1.00 35.27 H +ATOM 594 HG21 VAL A 52 13.940 -15.795 17.347 1.00 35.83 H +ATOM 595 HG22 VAL A 52 15.292 -16.000 18.453 1.00 35.83 H +ATOM 596 HG23 VAL A 52 15.104 -17.079 17.073 1.00 35.83 H +ATOM 597 N ARG A 53 13.596 -19.219 21.626 1.00 38.55 N +ATOM 598 CA ARG A 53 12.708 -19.929 22.540 1.00 41.08 C +ATOM 599 C ARG A 53 11.301 -19.320 22.495 1.00 42.23 C +ATOM 600 O ARG A 53 11.147 -18.142 22.817 1.00 42.18 O +ATOM 601 CB ARG A 53 13.308 -19.884 23.957 1.00 42.63 C +ATOM 602 CG ARG A 53 12.695 -20.937 24.895 1.00 47.38 C +ATOM 603 CD ARG A 53 13.301 -20.956 26.312 1.00 50.43 C +ATOM 604 NE ARG A 53 12.954 -19.765 27.106 1.00 55.27 N +ATOM 605 CZ ARG A 53 11.773 -19.503 27.694 1.00 56.95 C +ATOM 606 NH1 ARG A 53 10.725 -20.334 27.608 1.00 59.72 N +ATOM 607 NH2 ARG A 53 11.635 -18.378 28.398 1.00 58.53 N1+ +ATOM 608 H ARG A 53 14.210 -18.533 22.048 1.00 38.55 H +ATOM 609 HA ARG A 53 12.663 -20.969 22.216 1.00 41.08 H +ATOM 610 HB3 ARG A 53 13.209 -18.887 24.384 1.00 42.63 H +ATOM 611 HB2 ARG A 53 14.378 -20.065 23.894 1.00 42.63 H +ATOM 612 HG3 ARG A 53 12.747 -21.932 24.454 1.00 47.38 H +ATOM 613 HG2 ARG A 53 11.632 -20.710 24.970 1.00 47.38 H +ATOM 614 HD3 ARG A 53 14.386 -20.910 26.218 1.00 50.43 H +ATOM 615 HD2 ARG A 53 13.092 -21.887 26.839 1.00 50.43 H +ATOM 616 HE ARG A 53 13.688 -19.077 27.192 1.00 55.27 H +ATOM 617 HH12 ARG A 53 9.863 -20.138 28.096 1.00 59.72 H +ATOM 618 HH11 ARG A 53 10.810 -21.196 27.087 1.00 59.72 H +ATOM 619 HH22 ARG A 53 10.759 -18.164 28.851 1.00 58.53 H +ATOM 620 HH21 ARG A 53 12.418 -17.748 28.518 1.00 58.53 H +ATOM 621 N THR A 54 10.315 -20.130 22.084 1.00 44.25 N +ATOM 622 CA THR A 54 8.952 -19.675 21.795 1.00 46.39 C +ATOM 623 C THR A 54 7.912 -20.111 22.851 1.00 48.51 C +ATOM 624 O THR A 54 6.730 -19.818 22.669 1.00 47.93 O +ATOM 625 CB THR A 54 8.506 -20.154 20.387 1.00 46.41 C +ATOM 626 OG1 THR A 54 8.198 -21.537 20.340 1.00 47.70 O +ATOM 627 CG2 THR A 54 9.533 -19.812 19.297 1.00 45.46 C +ATOM 628 H THR A 54 10.518 -21.093 21.852 1.00 44.25 H +ATOM 629 HA THR A 54 8.923 -18.586 21.777 1.00 46.39 H +ATOM 630 HB THR A 54 7.588 -19.621 20.132 1.00 46.41 H +ATOM 631 HG1 THR A 54 7.416 -21.688 20.879 1.00 47.70 H +ATOM 632 HG21 THR A 54 9.094 -19.880 18.307 1.00 45.46 H +ATOM 633 HG22 THR A 54 9.909 -18.794 19.410 1.00 45.46 H +ATOM 634 HG23 THR A 54 10.385 -20.489 19.326 1.00 45.46 H +ATOM 635 N GLY A 55 8.352 -20.762 23.938 1.00 50.52 N +ATOM 636 CA GLY A 55 7.480 -21.176 25.034 1.00 54.71 C +ATOM 637 C GLY A 55 8.156 -22.294 25.833 1.00 58.31 C +ATOM 638 O GLY A 55 9.194 -22.820 25.432 1.00 58.28 O +ATOM 639 H GLY A 55 9.332 -20.992 24.022 1.00 50.52 H +ATOM 640 HA3 GLY A 55 6.524 -21.542 24.657 1.00 54.71 H +ATOM 641 HA2 GLY A 55 7.282 -20.322 25.684 1.00 54.71 H +ATOM 642 N GLY A 56 7.548 -22.653 26.974 1.00 60.67 N +ATOM 643 CA GLY A 56 8.051 -23.681 27.884 1.00 63.02 C +ATOM 644 C GLY A 56 8.911 -23.040 28.982 1.00 64.97 C +ATOM 645 O GLY A 56 8.605 -21.952 29.470 1.00 66.30 O +ATOM 646 H GLY A 56 6.699 -22.182 27.251 1.00 60.67 H +ATOM 647 HA3 GLY A 56 8.609 -24.451 27.350 1.00 63.02 H +ATOM 648 HA2 GLY A 56 7.202 -24.178 28.355 1.00 63.02 H +ATOM 649 N LEU A 57 9.960 -23.767 29.392 1.00 65.39 N +ATOM 650 CA LEU A 57 10.880 -23.457 30.487 1.00 66.24 C +ATOM 651 C LEU A 57 12.337 -23.533 29.994 1.00 66.92 C +ATOM 652 O LEU A 57 12.604 -24.014 28.895 1.00 67.15 O +ATOM 653 CB LEU A 57 10.671 -24.493 31.629 1.00 65.98 C +ATOM 654 CG LEU A 57 9.336 -24.417 32.408 1.00 66.38 C +ATOM 655 CD1 LEU A 57 9.050 -23.014 32.978 1.00 66.32 C +ATOM 656 CD2 LEU A 57 8.135 -25.026 31.654 1.00 66.04 C +ATOM 657 H LEU A 57 10.144 -24.652 28.934 1.00 65.39 H +ATOM 658 HA LEU A 57 10.716 -22.442 30.850 1.00 66.24 H +ATOM 659 HB3 LEU A 57 11.462 -24.359 32.369 1.00 65.98 H +ATOM 660 HB2 LEU A 57 10.814 -25.505 31.246 1.00 65.98 H +ATOM 661 HG LEU A 57 9.490 -25.064 33.273 1.00 66.38 H +ATOM 662 HD11 LEU A 57 8.654 -23.084 33.991 1.00 66.32 H +ATOM 663 HD12 LEU A 57 9.951 -22.404 33.034 1.00 66.32 H +ATOM 664 HD13 LEU A 57 8.323 -22.467 32.379 1.00 66.32 H +ATOM 665 HD21 LEU A 57 7.600 -25.731 32.291 1.00 66.04 H +ATOM 666 HD22 LEU A 57 7.417 -24.270 31.337 1.00 66.04 H +ATOM 667 HD23 LEU A 57 8.444 -25.576 30.766 1.00 66.04 H +ATOM 668 N ALA A 58 13.282 -23.106 30.847 1.00 67.23 N +ATOM 669 CA ALA A 58 14.722 -23.288 30.626 1.00 66.48 C +ATOM 670 C ALA A 58 15.191 -24.760 30.712 1.00 65.87 C +ATOM 671 O ALA A 58 16.263 -25.069 30.194 1.00 66.21 O +ATOM 672 CB ALA A 58 15.487 -22.411 31.626 1.00 67.06 C +ATOM 673 H ALA A 58 13.015 -22.712 31.737 1.00 67.23 H +ATOM 674 HA ALA A 58 14.957 -22.932 29.621 1.00 66.48 H +ATOM 675 HB1 ALA A 58 16.565 -22.487 31.477 1.00 67.06 H +ATOM 676 HB2 ALA A 58 15.218 -21.360 31.512 1.00 67.06 H +ATOM 677 HB3 ALA A 58 15.274 -22.698 32.657 1.00 67.06 H +ATOM 678 N ASP A 59 14.380 -25.629 31.341 1.00 64.61 N +ATOM 679 CA ASP A 59 14.613 -27.069 31.489 1.00 62.91 C +ATOM 680 C ASP A 59 14.027 -27.872 30.301 1.00 61.47 C +ATOM 681 O ASP A 59 14.523 -28.958 30.004 1.00 60.79 O +ATOM 682 CB ASP A 59 14.013 -27.543 32.841 1.00 64.61 C +ATOM 683 CG ASP A 59 14.357 -28.965 33.326 1.00 65.60 C +ATOM 684 OD1 ASP A 59 13.610 -29.438 34.211 1.00 65.91 O +ATOM 685 OD2 ASP A 59 15.424 -29.494 32.945 1.00 67.03 O1- +ATOM 686 H ASP A 59 13.523 -25.285 31.747 1.00 64.61 H +ATOM 687 HA ASP A 59 15.691 -27.240 31.504 1.00 62.91 H +ATOM 688 HB3 ASP A 59 12.928 -27.426 32.808 1.00 64.61 H +ATOM 689 HB2 ASP A 59 14.339 -26.855 33.623 1.00 64.61 H +ATOM 690 N LYS A 60 12.988 -27.332 29.640 1.00 60.27 N +ATOM 691 CA LYS A 60 12.234 -27.994 28.574 1.00 58.55 C +ATOM 692 C LYS A 60 11.502 -26.919 27.763 1.00 57.58 C +ATOM 693 O LYS A 60 10.641 -26.249 28.329 1.00 58.16 O +ATOM 694 CB LYS A 60 11.246 -29.008 29.208 1.00 58.27 C +ATOM 695 CG LYS A 60 10.230 -29.648 28.237 1.00 57.51 C +ATOM 696 CD LYS A 60 9.083 -30.356 28.971 1.00 57.75 C +ATOM 697 CE LYS A 60 7.980 -30.820 28.007 1.00 57.66 C +ATOM 698 NZ LYS A 60 6.835 -31.403 28.728 1.00 59.13 N1+ +ATOM 699 H LYS A 60 12.654 -26.418 29.908 1.00 60.27 H +ATOM 700 HA LYS A 60 12.925 -28.524 27.916 1.00 58.55 H +ATOM 701 HB3 LYS A 60 10.685 -28.487 29.985 1.00 58.27 H +ATOM 702 HB2 LYS A 60 11.796 -29.797 29.723 1.00 58.27 H +ATOM 703 HG3 LYS A 60 10.746 -30.354 27.585 1.00 57.51 H +ATOM 704 HG2 LYS A 60 9.787 -28.901 27.578 1.00 57.51 H +ATOM 705 HD3 LYS A 60 8.663 -29.680 29.719 1.00 57.75 H +ATOM 706 HD2 LYS A 60 9.484 -31.210 29.519 1.00 57.75 H +ATOM 707 HE3 LYS A 60 8.374 -31.558 27.308 1.00 57.66 H +ATOM 708 HE2 LYS A 60 7.615 -29.979 27.416 1.00 57.66 H +ATOM 709 HZ1 LYS A 60 6.441 -30.714 29.352 1.00 59.13 H +ATOM 710 HZ2 LYS A 60 6.132 -31.697 28.064 1.00 59.13 H +ATOM 711 HZ3 LYS A 60 7.144 -32.202 29.263 1.00 59.13 H +ATOM 712 N SER A 61 11.804 -26.800 26.461 1.00 55.59 N +ATOM 713 CA SER A 61 11.184 -25.804 25.584 1.00 52.94 C +ATOM 714 C SER A 61 11.201 -26.196 24.105 1.00 51.62 C +ATOM 715 O SER A 61 12.091 -26.917 23.654 1.00 50.85 O +ATOM 716 CB SER A 61 11.836 -24.420 25.787 1.00 53.73 C +ATOM 717 OG SER A 61 13.243 -24.448 25.640 1.00 53.69 O +ATOM 718 H SER A 61 12.502 -27.395 26.037 1.00 55.59 H +ATOM 719 HA SER A 61 10.130 -25.722 25.859 1.00 52.94 H +ATOM 720 HB3 SER A 61 11.550 -23.993 26.742 1.00 53.73 H +ATOM 721 HB2 SER A 61 11.464 -23.725 25.037 1.00 53.73 H +ATOM 722 HG SER A 61 13.613 -24.916 26.393 1.00 53.69 H +ATOM 723 N SER A 62 10.226 -25.619 23.385 1.00 49.47 N +ATOM 724 CA SER A 62 10.166 -25.547 21.930 1.00 48.07 C +ATOM 725 C SER A 62 10.924 -24.301 21.439 1.00 46.24 C +ATOM 726 O SER A 62 10.928 -23.273 22.124 1.00 45.55 O +ATOM 727 CB SER A 62 8.681 -25.529 21.509 1.00 47.76 C +ATOM 728 OG SER A 62 8.012 -24.350 21.921 1.00 48.25 O +ATOM 729 H SER A 62 9.546 -25.042 23.859 1.00 49.47 H +ATOM 730 HA SER A 62 10.634 -26.439 21.509 1.00 48.07 H +ATOM 731 HB3 SER A 62 8.157 -26.394 21.918 1.00 47.76 H +ATOM 732 HB2 SER A 62 8.601 -25.603 20.423 1.00 47.76 H +ATOM 733 HG SER A 62 8.378 -23.607 21.434 1.00 48.25 H +ATOM 734 N ARG A 63 11.545 -24.421 20.255 1.00 44.90 N +ATOM 735 CA ARG A 63 12.338 -23.359 19.639 1.00 44.08 C +ATOM 736 C ARG A 63 12.109 -23.317 18.121 1.00 42.93 C +ATOM 737 O ARG A 63 11.867 -24.360 17.511 1.00 42.40 O +ATOM 738 CB ARG A 63 13.844 -23.546 19.956 1.00 45.10 C +ATOM 739 CG ARG A 63 14.193 -23.757 21.448 1.00 45.50 C +ATOM 740 CD ARG A 63 15.702 -23.796 21.744 1.00 47.24 C +ATOM 741 NE ARG A 63 16.331 -22.470 21.625 1.00 48.56 N +ATOM 742 CZ ARG A 63 16.618 -21.599 22.607 1.00 50.82 C +ATOM 743 NH1 ARG A 63 17.148 -20.416 22.281 1.00 50.08 N +ATOM 744 NH2 ARG A 63 16.394 -21.879 23.899 1.00 53.19 N1+ +ATOM 745 H ARG A 63 11.485 -25.284 19.733 1.00 44.90 H +ATOM 746 HA ARG A 63 11.999 -22.409 20.047 1.00 44.08 H +ATOM 747 HB3 ARG A 63 14.386 -22.681 19.572 1.00 45.10 H +ATOM 748 HB2 ARG A 63 14.222 -24.405 19.400 1.00 45.10 H +ATOM 749 HG3 ARG A 63 13.721 -24.643 21.872 1.00 45.50 H +ATOM 750 HG2 ARG A 63 13.765 -22.912 21.986 1.00 45.50 H +ATOM 751 HD3 ARG A 63 16.183 -24.375 20.955 1.00 47.24 H +ATOM 752 HD2 ARG A 63 15.931 -24.323 22.671 1.00 47.24 H +ATOM 753 HE ARG A 63 16.567 -22.205 20.675 1.00 48.56 H +ATOM 754 HH12 ARG A 63 17.389 -19.747 22.998 1.00 50.08 H +ATOM 755 HH11 ARG A 63 17.317 -20.176 21.313 1.00 50.08 H +ATOM 756 HH22 ARG A 63 16.697 -21.240 24.619 1.00 53.19 H +ATOM 757 HH21 ARG A 63 16.017 -22.779 24.158 1.00 53.19 H +ATOM 758 N LYS A 64 12.243 -22.113 17.542 1.00 42.57 N +ATOM 759 CA LYS A 64 12.290 -21.874 16.099 1.00 41.26 C +ATOM 760 C LYS A 64 13.727 -21.515 15.707 1.00 38.78 C +ATOM 761 O LYS A 64 14.285 -20.579 16.277 1.00 38.88 O +ATOM 762 CB LYS A 64 11.341 -20.719 15.719 1.00 43.63 C +ATOM 763 CG LYS A 64 9.853 -21.103 15.742 1.00 47.59 C +ATOM 764 CD LYS A 64 8.963 -19.947 15.245 1.00 49.93 C +ATOM 765 CE LYS A 64 7.452 -20.233 15.277 1.00 51.92 C +ATOM 766 NZ LYS A 64 6.896 -20.212 16.643 1.00 52.03 N1+ +ATOM 767 H LYS A 64 12.452 -21.312 18.124 1.00 42.57 H +ATOM 768 HA LYS A 64 11.987 -22.768 15.550 1.00 41.26 H +ATOM 769 HB3 LYS A 64 11.573 -20.396 14.702 1.00 43.63 H +ATOM 770 HB2 LYS A 64 11.521 -19.851 16.356 1.00 43.63 H +ATOM 771 HG3 LYS A 64 9.567 -21.418 16.744 1.00 47.59 H +ATOM 772 HG2 LYS A 64 9.698 -21.971 15.100 1.00 47.59 H +ATOM 773 HD3 LYS A 64 9.240 -19.718 14.216 1.00 49.93 H +ATOM 774 HD2 LYS A 64 9.182 -19.042 15.811 1.00 49.93 H +ATOM 775 HE3 LYS A 64 7.235 -21.193 14.807 1.00 51.92 H +ATOM 776 HE2 LYS A 64 6.929 -19.471 14.698 1.00 51.92 H +ATOM 777 HZ1 LYS A 64 7.349 -20.921 17.203 1.00 52.03 H +ATOM 778 HZ2 LYS A 64 7.054 -19.304 17.057 1.00 52.03 H +ATOM 779 HZ3 LYS A 64 5.904 -20.396 16.605 1.00 52.03 H +ATOM 780 N THR A 65 14.279 -22.251 14.731 1.00 38.63 N +ATOM 781 CA THR A 65 15.624 -22.045 14.195 1.00 37.37 C +ATOM 782 C THR A 65 15.543 -21.489 12.763 1.00 37.22 C +ATOM 783 O THR A 65 14.638 -21.840 12.004 1.00 36.21 O +ATOM 784 CB THR A 65 16.422 -23.376 14.149 1.00 38.99 C +ATOM 785 OG1 THR A 65 15.835 -24.338 13.291 1.00 41.01 O +ATOM 786 CG2 THR A 65 16.615 -24.005 15.536 1.00 37.71 C +ATOM 787 H THR A 65 13.750 -22.996 14.299 1.00 38.63 H +ATOM 788 HA THR A 65 16.176 -21.339 14.813 1.00 37.37 H +ATOM 789 HB THR A 65 17.416 -23.169 13.748 1.00 38.99 H +ATOM 790 HG1 THR A 65 15.820 -23.986 12.397 1.00 41.01 H +ATOM 791 HG21 THR A 65 17.197 -24.926 15.470 1.00 37.71 H +ATOM 792 HG22 THR A 65 17.158 -23.326 16.189 1.00 37.71 H +ATOM 793 HG23 THR A 65 15.664 -24.247 16.012 1.00 37.71 H +ATOM 794 N TYR A 66 16.520 -20.633 12.437 1.00 35.89 N +ATOM 795 CA TYR A 66 16.673 -19.986 11.139 1.00 35.61 C +ATOM 796 C TYR A 66 18.160 -19.982 10.792 1.00 34.68 C +ATOM 797 O TYR A 66 18.961 -19.578 11.634 1.00 34.69 O +ATOM 798 CB TYR A 66 16.185 -18.525 11.219 1.00 35.24 C +ATOM 799 CG TYR A 66 14.757 -18.318 11.670 1.00 35.81 C +ATOM 800 CD1 TYR A 66 14.474 -18.140 13.042 1.00 36.83 C +ATOM 801 CD2 TYR A 66 13.711 -18.298 10.726 1.00 36.87 C +ATOM 802 CE1 TYR A 66 13.147 -17.964 13.471 1.00 37.60 C +ATOM 803 CE2 TYR A 66 12.385 -18.118 11.157 1.00 38.67 C +ATOM 804 CZ TYR A 66 12.101 -17.957 12.529 1.00 38.55 C +ATOM 805 OH TYR A 66 10.815 -17.800 12.953 1.00 40.55 O +ATOM 806 H TYR A 66 17.215 -20.385 13.128 1.00 35.89 H +ATOM 807 HA TYR A 66 16.119 -20.521 10.365 1.00 35.61 H +ATOM 808 HB3 TYR A 66 16.315 -18.038 10.252 1.00 35.24 H +ATOM 809 HB2 TYR A 66 16.813 -17.985 11.926 1.00 35.24 H +ATOM 810 HD1 TYR A 66 15.272 -18.152 13.770 1.00 36.83 H +ATOM 811 HD2 TYR A 66 13.922 -18.428 9.675 1.00 36.87 H +ATOM 812 HE1 TYR A 66 12.933 -17.841 14.523 1.00 37.60 H +ATOM 813 HE2 TYR A 66 11.590 -18.115 10.428 1.00 38.67 H +ATOM 814 HH TYR A 66 10.173 -17.850 12.234 1.00 40.55 H +ATOM 815 N THR A 67 18.492 -20.370 9.553 1.00 34.56 N +ATOM 816 CA THR A 67 19.838 -20.225 9.001 1.00 35.90 C +ATOM 817 C THR A 67 19.908 -18.928 8.175 1.00 34.33 C +ATOM 818 O THR A 67 18.936 -18.573 7.507 1.00 36.54 O +ATOM 819 CB THR A 67 20.212 -21.422 8.088 1.00 35.84 C +ATOM 820 OG1 THR A 67 20.182 -22.608 8.859 1.00 40.38 O +ATOM 821 CG2 THR A 67 21.604 -21.340 7.430 1.00 38.08 C +ATOM 822 H THR A 67 17.781 -20.696 8.915 1.00 34.56 H +ATOM 823 HA THR A 67 20.568 -20.176 9.809 1.00 35.90 H +ATOM 824 HB THR A 67 19.461 -21.532 7.303 1.00 35.84 H +ATOM 825 HG1 THR A 67 20.919 -22.602 9.475 1.00 40.38 H +ATOM 826 HG21 THR A 67 21.846 -22.267 6.910 1.00 38.08 H +ATOM 827 HG22 THR A 67 21.661 -20.541 6.690 1.00 38.08 H +ATOM 828 HG23 THR A 67 22.384 -21.164 8.173 1.00 38.08 H +ATOM 829 N PHE A 68 21.066 -18.259 8.238 1.00 33.30 N +ATOM 830 CA PHE A 68 21.389 -17.033 7.511 1.00 34.46 C +ATOM 831 C PHE A 68 22.759 -17.169 6.829 1.00 35.45 C +ATOM 832 O PHE A 68 23.421 -18.194 6.989 1.00 35.78 O +ATOM 833 CB PHE A 68 21.330 -15.843 8.491 1.00 32.88 C +ATOM 834 CG PHE A 68 19.921 -15.483 8.914 1.00 32.39 C +ATOM 835 CD1 PHE A 68 19.367 -16.013 10.098 1.00 30.02 C +ATOM 836 CD2 PHE A 68 19.095 -14.754 8.036 1.00 32.12 C +ATOM 837 CE1 PHE A 68 18.043 -15.746 10.414 1.00 32.75 C +ATOM 838 CE2 PHE A 68 17.775 -14.503 8.376 1.00 32.46 C +ATOM 839 CZ PHE A 68 17.250 -14.992 9.562 1.00 30.39 C +ATOM 840 H PHE A 68 21.812 -18.624 8.818 1.00 33.30 H +ATOM 841 HA PHE A 68 20.670 -16.864 6.708 1.00 34.46 H +ATOM 842 HB3 PHE A 68 21.772 -14.953 8.047 1.00 32.88 H +ATOM 843 HB2 PHE A 68 21.927 -16.056 9.378 1.00 32.88 H +ATOM 844 HD1 PHE A 68 19.971 -16.617 10.760 1.00 30.02 H +ATOM 845 HD2 PHE A 68 19.488 -14.390 7.099 1.00 32.12 H +ATOM 846 HE1 PHE A 68 17.621 -16.109 11.333 1.00 32.75 H +ATOM 847 HE2 PHE A 68 17.161 -13.925 7.710 1.00 32.46 H +ATOM 848 HZ PHE A 68 16.224 -14.788 9.826 1.00 30.39 H +ATOM 849 N ASP A 69 23.163 -16.140 6.066 1.00 35.34 N +ATOM 850 CA ASP A 69 24.493 -16.049 5.450 1.00 36.28 C +ATOM 851 C ASP A 69 25.610 -15.856 6.493 1.00 36.61 C +ATOM 852 O ASP A 69 26.680 -16.434 6.315 1.00 37.28 O +ATOM 853 CB ASP A 69 24.591 -14.990 4.326 1.00 36.93 C +ATOM 854 CG ASP A 69 23.641 -15.265 3.149 1.00 38.87 C +ATOM 855 OD1 ASP A 69 22.434 -14.959 3.276 1.00 40.13 O +ATOM 856 OD2 ASP A 69 24.112 -15.913 2.188 1.00 42.22 O1- +ATOM 857 H ASP A 69 22.567 -15.331 5.942 1.00 35.34 H +ATOM 858 HA ASP A 69 24.684 -17.016 4.980 1.00 36.28 H +ATOM 859 HB3 ASP A 69 25.615 -14.931 3.951 1.00 36.93 H +ATOM 860 HB2 ASP A 69 24.363 -14.000 4.722 1.00 36.93 H +ATOM 861 N MET A 70 25.328 -15.109 7.573 1.00 36.59 N +ATOM 862 CA MET A 70 26.141 -15.024 8.791 1.00 35.56 C +ATOM 863 C MET A 70 25.221 -14.753 9.990 1.00 34.74 C +ATOM 864 O MET A 70 24.092 -14.298 9.811 1.00 31.88 O +ATOM 865 CB MET A 70 27.245 -13.939 8.688 1.00 39.47 C +ATOM 866 CG MET A 70 28.322 -14.212 7.626 1.00 45.06 C +ATOM 867 SD MET A 70 29.760 -13.111 7.657 1.00 51.52 S +ATOM 868 CE MET A 70 29.062 -11.670 6.820 1.00 51.68 C +ATOM 869 H MET A 70 24.422 -14.665 7.634 1.00 36.59 H +ATOM 870 HA MET A 70 26.610 -15.994 8.966 1.00 35.56 H +ATOM 871 HB3 MET A 70 27.748 -13.844 9.652 1.00 39.47 H +ATOM 872 HB2 MET A 70 26.797 -12.965 8.505 1.00 39.47 H +ATOM 873 HG3 MET A 70 27.894 -14.157 6.626 1.00 45.06 H +ATOM 874 HG2 MET A 70 28.697 -15.228 7.752 1.00 45.06 H +ATOM 875 HE1 MET A 70 29.856 -10.977 6.548 1.00 51.68 H +ATOM 876 HE2 MET A 70 28.535 -11.960 5.911 1.00 51.68 H +ATOM 877 HE3 MET A 70 28.369 -11.165 7.488 1.00 51.68 H +ATOM 878 N VAL A 71 25.721 -15.024 11.204 1.00 32.66 N +ATOM 879 CA VAL A 71 25.039 -14.676 12.450 1.00 31.78 C +ATOM 880 C VAL A 71 26.083 -14.187 13.464 1.00 32.81 C +ATOM 881 O VAL A 71 27.161 -14.770 13.568 1.00 31.61 O +ATOM 882 CB VAL A 71 24.218 -15.858 13.050 1.00 31.25 C +ATOM 883 CG1 VAL A 71 23.634 -15.563 14.447 1.00 33.70 C +ATOM 884 CG2 VAL A 71 23.070 -16.276 12.115 1.00 33.69 C +ATOM 885 H VAL A 71 26.654 -15.397 11.301 1.00 32.66 H +ATOM 886 HA VAL A 71 24.354 -13.848 12.264 1.00 31.78 H +ATOM 887 HB VAL A 71 24.876 -16.723 13.154 1.00 31.25 H +ATOM 888 HG11 VAL A 71 22.986 -16.367 14.791 1.00 33.70 H +ATOM 889 HG12 VAL A 71 24.415 -15.453 15.197 1.00 33.70 H +ATOM 890 HG13 VAL A 71 23.042 -14.647 14.442 1.00 33.70 H +ATOM 891 HG21 VAL A 71 22.454 -17.056 12.556 1.00 33.69 H +ATOM 892 HG22 VAL A 71 22.414 -15.436 11.887 1.00 33.69 H +ATOM 893 HG23 VAL A 71 23.449 -16.666 11.172 1.00 33.69 H +ATOM 894 N PHE A 72 25.719 -13.119 14.185 1.00 31.41 N +ATOM 895 CA PHE A 72 26.526 -12.450 15.196 1.00 30.44 C +ATOM 896 C PHE A 72 25.753 -12.437 16.520 1.00 33.41 C +ATOM 897 O PHE A 72 24.587 -12.040 16.544 1.00 34.20 O +ATOM 898 CB PHE A 72 26.847 -11.021 14.712 1.00 31.40 C +ATOM 899 CG PHE A 72 27.760 -10.979 13.499 1.00 31.93 C +ATOM 900 CD1 PHE A 72 29.136 -11.266 13.630 1.00 29.89 C +ATOM 901 CD2 PHE A 72 27.205 -10.842 12.208 1.00 33.00 C +ATOM 902 CE1 PHE A 72 29.929 -11.384 12.496 1.00 31.75 C +ATOM 903 CE2 PHE A 72 28.014 -10.967 11.089 1.00 32.57 C +ATOM 904 CZ PHE A 72 29.364 -11.249 11.234 1.00 33.90 C +ATOM 905 H PHE A 72 24.816 -12.695 14.010 1.00 31.41 H +ATOM 906 HA PHE A 72 27.465 -12.985 15.353 1.00 30.44 H +ATOM 907 HB3 PHE A 72 27.306 -10.456 15.517 1.00 31.40 H +ATOM 908 HB2 PHE A 72 25.931 -10.482 14.472 1.00 31.40 H +ATOM 909 HD1 PHE A 72 29.570 -11.420 14.606 1.00 29.89 H +ATOM 910 HD2 PHE A 72 26.147 -10.667 12.084 1.00 33.00 H +ATOM 911 HE1 PHE A 72 30.981 -11.610 12.593 1.00 31.75 H +ATOM 912 HE2 PHE A 72 27.585 -10.874 10.101 1.00 32.57 H +ATOM 913 HZ PHE A 72 29.965 -11.388 10.350 1.00 33.90 H +ATOM 914 N GLY A 73 26.425 -12.873 17.595 1.00 33.64 N +ATOM 915 CA GLY A 73 25.866 -12.923 18.944 1.00 32.52 C +ATOM 916 C GLY A 73 26.119 -11.609 19.694 1.00 32.30 C +ATOM 917 O GLY A 73 26.727 -10.675 19.171 1.00 31.71 O +ATOM 918 H GLY A 73 27.381 -13.180 17.486 1.00 33.64 H +ATOM 919 HA3 GLY A 73 26.341 -13.742 19.485 1.00 32.52 H +ATOM 920 HA2 GLY A 73 24.796 -13.133 18.922 1.00 32.52 H +ATOM 921 N ALA A 74 25.654 -11.570 20.953 1.00 32.62 N +ATOM 922 CA ALA A 74 25.782 -10.462 21.907 1.00 32.76 C +ATOM 923 C ALA A 74 27.219 -9.977 22.186 1.00 33.54 C +ATOM 924 O ALA A 74 27.400 -8.803 22.505 1.00 34.23 O +ATOM 925 CB ALA A 74 25.111 -10.902 23.215 1.00 33.34 C +ATOM 926 H ALA A 74 25.162 -12.377 21.306 1.00 32.62 H +ATOM 927 HA ALA A 74 25.233 -9.608 21.511 1.00 32.76 H +ATOM 928 HB1 ALA A 74 25.340 -10.228 24.037 1.00 33.34 H +ATOM 929 HB2 ALA A 74 24.026 -10.938 23.104 1.00 33.34 H +ATOM 930 HB3 ALA A 74 25.445 -11.895 23.519 1.00 33.34 H +ATOM 931 N SER A 75 28.206 -10.877 22.054 1.00 34.01 N +ATOM 932 CA SER A 75 29.630 -10.609 22.262 1.00 34.43 C +ATOM 933 C SER A 75 30.325 -9.871 21.098 1.00 34.89 C +ATOM 934 O SER A 75 31.456 -9.423 21.286 1.00 35.01 O +ATOM 935 CB SER A 75 30.322 -11.951 22.582 1.00 34.37 C +ATOM 936 OG SER A 75 30.361 -12.814 21.460 1.00 36.98 O +ATOM 937 H SER A 75 27.980 -11.824 21.783 1.00 34.01 H +ATOM 938 HA SER A 75 29.725 -9.972 23.144 1.00 34.43 H +ATOM 939 HB3 SER A 75 29.817 -12.458 23.405 1.00 34.37 H +ATOM 940 HB2 SER A 75 31.348 -11.775 22.912 1.00 34.37 H +ATOM 941 HG SER A 75 31.027 -12.491 20.847 1.00 36.98 H +ATOM 942 N THR A 76 29.667 -9.780 19.928 1.00 34.17 N +ATOM 943 CA THR A 76 30.229 -9.228 18.694 1.00 32.21 C +ATOM 944 C THR A 76 30.534 -7.723 18.814 1.00 32.29 C +ATOM 945 O THR A 76 29.636 -6.940 19.122 1.00 33.66 O +ATOM 946 CB THR A 76 29.264 -9.433 17.497 1.00 32.67 C +ATOM 947 OG1 THR A 76 29.038 -10.820 17.342 1.00 34.27 O +ATOM 948 CG2 THR A 76 29.752 -8.888 16.145 1.00 30.68 C +ATOM 949 H THR A 76 28.727 -10.146 19.861 1.00 34.17 H +ATOM 950 HA THR A 76 31.157 -9.765 18.486 1.00 32.21 H +ATOM 951 HB THR A 76 28.303 -8.970 17.723 1.00 32.67 H +ATOM 952 HG1 THR A 76 28.499 -11.118 18.079 1.00 34.27 H +ATOM 953 HG21 THR A 76 28.994 -8.998 15.372 1.00 30.68 H +ATOM 954 HG22 THR A 76 29.980 -7.827 16.190 1.00 30.68 H +ATOM 955 HG23 THR A 76 30.641 -9.419 15.811 1.00 30.68 H +ATOM 956 N LYS A 77 31.793 -7.357 18.541 1.00 29.27 N +ATOM 957 CA LYS A 77 32.267 -5.976 18.504 1.00 30.93 C +ATOM 958 C LYS A 77 32.053 -5.354 17.115 1.00 29.85 C +ATOM 959 O LYS A 77 31.833 -6.067 16.137 1.00 28.59 O +ATOM 960 CB LYS A 77 33.761 -5.957 18.893 1.00 30.84 C +ATOM 961 CG LYS A 77 34.063 -6.449 20.324 1.00 33.75 C +ATOM 962 CD LYS A 77 33.336 -5.696 21.455 1.00 39.24 C +ATOM 963 CE LYS A 77 33.618 -4.182 21.480 1.00 41.33 C +ATOM 964 NZ LYS A 77 32.957 -3.518 22.617 1.00 40.00 N1+ +ATOM 965 H LYS A 77 32.469 -8.065 18.279 1.00 29.27 H +ATOM 966 HA LYS A 77 31.702 -5.374 19.217 1.00 30.93 H +ATOM 967 HB3 LYS A 77 34.155 -4.946 18.786 1.00 30.84 H +ATOM 968 HB2 LYS A 77 34.328 -6.566 18.189 1.00 30.84 H +ATOM 969 HG3 LYS A 77 35.138 -6.386 20.493 1.00 33.75 H +ATOM 970 HG2 LYS A 77 33.822 -7.511 20.396 1.00 33.75 H +ATOM 971 HD3 LYS A 77 33.645 -6.137 22.405 1.00 39.24 H +ATOM 972 HD2 LYS A 77 32.263 -5.882 21.388 1.00 39.24 H +ATOM 973 HE3 LYS A 77 33.267 -3.708 20.563 1.00 41.33 H +ATOM 974 HE2 LYS A 77 34.692 -3.999 21.546 1.00 41.33 H +ATOM 975 HZ1 LYS A 77 33.292 -3.915 23.483 1.00 40.00 H +ATOM 976 HZ2 LYS A 77 33.164 -2.530 22.600 1.00 40.00 H +ATOM 977 HZ3 LYS A 77 31.957 -3.651 22.553 1.00 40.00 H +ATOM 978 N GLN A 78 32.143 -4.017 17.053 1.00 28.05 N +ATOM 979 CA GLN A 78 32.015 -3.236 15.820 1.00 27.78 C +ATOM 980 C GLN A 78 33.085 -3.566 14.763 1.00 28.95 C +ATOM 981 O GLN A 78 32.777 -3.556 13.572 1.00 25.92 O +ATOM 982 CB GLN A 78 32.124 -1.743 16.156 1.00 27.45 C +ATOM 983 CG GLN A 78 31.092 -1.171 17.144 1.00 25.90 C +ATOM 984 CD GLN A 78 29.726 -0.917 16.518 1.00 24.67 C +ATOM 985 OE1 GLN A 78 29.121 -1.813 15.941 1.00 25.98 O +ATOM 986 NE2 GLN A 78 29.217 0.305 16.656 1.00 22.88 N +ATOM 987 H GLN A 78 32.325 -3.488 17.893 1.00 28.05 H +ATOM 988 HA GLN A 78 31.040 -3.449 15.380 1.00 27.78 H +ATOM 989 HB3 GLN A 78 32.078 -1.186 15.221 1.00 27.45 H +ATOM 990 HB2 GLN A 78 33.113 -1.556 16.570 1.00 27.45 H +ATOM 991 HG3 GLN A 78 31.474 -0.219 17.501 1.00 25.90 H +ATOM 992 HG2 GLN A 78 30.980 -1.802 18.026 1.00 25.90 H +ATOM 993 HE22 GLN A 78 28.300 0.518 16.278 1.00 22.88 H +ATOM 994 HE21 GLN A 78 29.726 1.032 17.144 1.00 22.88 H +ATOM 995 N ILE A 79 34.312 -3.860 15.227 1.00 27.36 N +ATOM 996 CA ILE A 79 35.437 -4.293 14.400 1.00 29.06 C +ATOM 997 C ILE A 79 35.202 -5.674 13.749 1.00 27.29 C +ATOM 998 O ILE A 79 35.612 -5.864 12.606 1.00 27.78 O +ATOM 999 CB ILE A 79 36.767 -4.300 15.218 1.00 30.11 C +ATOM 1000 CG1 ILE A 79 38.034 -4.597 14.384 1.00 32.36 C +ATOM 1001 CG2 ILE A 79 36.739 -5.239 16.442 1.00 27.95 C +ATOM 1002 CD1 ILE A 79 38.249 -3.654 13.192 1.00 34.09 C +ATOM 1003 H ILE A 79 34.481 -3.839 16.222 1.00 27.36 H +ATOM 1004 HA ILE A 79 35.528 -3.560 13.597 1.00 29.06 H +ATOM 1005 HB ILE A 79 36.887 -3.288 15.609 1.00 30.11 H +ATOM 1006 HG13 ILE A 79 38.019 -5.628 14.037 1.00 32.36 H +ATOM 1007 HG12 ILE A 79 38.909 -4.524 15.030 1.00 32.36 H +ATOM 1008 HG21 ILE A 79 37.631 -5.104 17.055 1.00 27.95 H +ATOM 1009 HG22 ILE A 79 35.881 -5.043 17.081 1.00 27.95 H +ATOM 1010 HG23 ILE A 79 36.709 -6.287 16.149 1.00 27.95 H +ATOM 1011 HD11 ILE A 79 39.256 -3.766 12.789 1.00 34.09 H +ATOM 1012 HD12 ILE A 79 37.549 -3.863 12.383 1.00 34.09 H +ATOM 1013 HD13 ILE A 79 38.125 -2.612 13.483 1.00 34.09 H +ATOM 1014 N ASP A 80 34.496 -6.576 14.456 1.00 28.59 N +ATOM 1015 CA ASP A 80 34.096 -7.901 13.971 1.00 27.29 C +ATOM 1016 C ASP A 80 33.113 -7.801 12.795 1.00 29.89 C +ATOM 1017 O ASP A 80 33.333 -8.469 11.786 1.00 27.87 O +ATOM 1018 CB ASP A 80 33.499 -8.817 15.069 1.00 28.62 C +ATOM 1019 CG ASP A 80 34.316 -9.001 16.360 1.00 31.56 C +ATOM 1020 OD1 ASP A 80 33.704 -9.485 17.337 1.00 29.84 O +ATOM 1021 OD2 ASP A 80 35.545 -8.768 16.344 1.00 31.94 O1- +ATOM 1022 H ASP A 80 34.181 -6.339 15.385 1.00 28.59 H +ATOM 1023 HA ASP A 80 34.999 -8.385 13.593 1.00 27.29 H +ATOM 1024 HB3 ASP A 80 33.320 -9.811 14.655 1.00 28.62 H +ATOM 1025 HB2 ASP A 80 32.531 -8.417 15.362 1.00 28.62 H +ATOM 1026 N VAL A 81 32.088 -6.936 12.927 1.00 26.47 N +ATOM 1027 CA VAL A 81 31.121 -6.618 11.870 1.00 27.06 C +ATOM 1028 C VAL A 81 31.795 -5.975 10.643 1.00 27.68 C +ATOM 1029 O VAL A 81 31.490 -6.368 9.518 1.00 27.78 O +ATOM 1030 CB VAL A 81 29.992 -5.665 12.372 1.00 26.45 C +ATOM 1031 CG1 VAL A 81 29.049 -5.125 11.271 1.00 26.19 C +ATOM 1032 CG2 VAL A 81 29.156 -6.336 13.473 1.00 24.32 C +ATOM 1033 H VAL A 81 31.979 -6.430 13.796 1.00 26.47 H +ATOM 1034 HA VAL A 81 30.666 -7.557 11.547 1.00 27.06 H +ATOM 1035 HB VAL A 81 30.461 -4.793 12.830 1.00 26.45 H +ATOM 1036 HG11 VAL A 81 28.219 -4.569 11.705 1.00 26.19 H +ATOM 1037 HG12 VAL A 81 29.553 -4.438 10.591 1.00 26.19 H +ATOM 1038 HG13 VAL A 81 28.625 -5.937 10.679 1.00 26.19 H +ATOM 1039 HG21 VAL A 81 28.342 -5.691 13.801 1.00 24.32 H +ATOM 1040 HG22 VAL A 81 28.719 -7.274 13.129 1.00 24.32 H +ATOM 1041 HG23 VAL A 81 29.766 -6.549 14.348 1.00 24.32 H +ATOM 1042 N TYR A 82 32.711 -5.020 10.877 1.00 31.58 N +ATOM 1043 CA TYR A 82 33.408 -4.314 9.808 1.00 34.08 C +ATOM 1044 C TYR A 82 34.322 -5.230 8.971 1.00 34.35 C +ATOM 1045 O TYR A 82 34.248 -5.177 7.746 1.00 35.44 O +ATOM 1046 CB TYR A 82 34.152 -3.082 10.357 1.00 37.56 C +ATOM 1047 CG TYR A 82 34.718 -2.221 9.244 1.00 40.86 C +ATOM 1048 CD1 TYR A 82 36.027 -2.444 8.767 1.00 42.74 C +ATOM 1049 CD2 TYR A 82 33.891 -1.271 8.611 1.00 41.86 C +ATOM 1050 CE1 TYR A 82 36.479 -1.771 7.618 1.00 44.29 C +ATOM 1051 CE2 TYR A 82 34.356 -0.578 7.479 1.00 43.80 C +ATOM 1052 CZ TYR A 82 35.638 -0.849 6.968 1.00 45.95 C +ATOM 1053 OH TYR A 82 36.059 -0.227 5.834 1.00 47.94 O +ATOM 1054 H TYR A 82 32.915 -4.733 11.826 1.00 31.58 H +ATOM 1055 HA TYR A 82 32.635 -3.937 9.137 1.00 34.08 H +ATOM 1056 HB3 TYR A 82 34.951 -3.382 11.038 1.00 37.56 H +ATOM 1057 HB2 TYR A 82 33.465 -2.472 10.945 1.00 37.56 H +ATOM 1058 HD1 TYR A 82 36.662 -3.177 9.242 1.00 42.74 H +ATOM 1059 HD2 TYR A 82 32.887 -1.096 8.969 1.00 41.86 H +ATOM 1060 HE1 TYR A 82 37.464 -1.978 7.225 1.00 44.29 H +ATOM 1061 HE2 TYR A 82 33.716 0.140 6.990 1.00 43.80 H +ATOM 1062 HH TYR A 82 35.398 0.358 5.457 1.00 47.94 H +ATOM 1063 N ARG A 83 35.144 -6.056 9.637 1.00 33.61 N +ATOM 1064 CA ARG A 83 36.062 -7.003 8.998 1.00 33.79 C +ATOM 1065 C ARG A 83 35.344 -8.068 8.154 1.00 32.60 C +ATOM 1066 O ARG A 83 35.787 -8.337 7.039 1.00 31.20 O +ATOM 1067 CB ARG A 83 36.916 -7.697 10.076 1.00 33.24 C +ATOM 1068 CG ARG A 83 38.028 -6.810 10.662 1.00 34.93 C +ATOM 1069 CD ARG A 83 38.706 -7.420 11.905 1.00 36.32 C +ATOM 1070 NE ARG A 83 39.373 -8.706 11.627 1.00 35.56 N +ATOM 1071 CZ ARG A 83 40.584 -8.918 11.080 1.00 37.72 C +ATOM 1072 NH1 ARG A 83 41.398 -7.911 10.726 1.00 36.80 N +ATOM 1073 NH2 ARG A 83 40.987 -10.179 10.880 1.00 38.76 N1+ +ATOM 1074 H ARG A 83 35.147 -6.047 10.650 1.00 33.61 H +ATOM 1075 HA ARG A 83 36.721 -6.447 8.327 1.00 33.79 H +ATOM 1076 HB3 ARG A 83 37.394 -8.576 9.641 1.00 33.24 H +ATOM 1077 HB2 ARG A 83 36.269 -8.073 10.871 1.00 33.24 H +ATOM 1078 HG3 ARG A 83 37.666 -5.809 10.897 1.00 34.93 H +ATOM 1079 HG2 ARG A 83 38.775 -6.665 9.880 1.00 34.93 H +ATOM 1080 HD3 ARG A 83 37.937 -7.639 12.647 1.00 36.32 H +ATOM 1081 HD2 ARG A 83 39.382 -6.707 12.377 1.00 36.32 H +ATOM 1082 HE ARG A 83 38.815 -9.520 11.845 1.00 35.56 H +ATOM 1083 HH12 ARG A 83 42.302 -8.097 10.317 1.00 36.80 H +ATOM 1084 HH11 ARG A 83 41.108 -6.955 10.874 1.00 36.80 H +ATOM 1085 HH22 ARG A 83 41.891 -10.369 10.471 1.00 38.76 H +ATOM 1086 HH21 ARG A 83 40.394 -10.953 11.141 1.00 38.76 H +ATOM 1087 N SER A 84 34.278 -8.663 8.710 1.00 29.89 N +ATOM 1088 CA SER A 84 33.582 -9.798 8.109 1.00 33.65 C +ATOM 1089 C SER A 84 32.568 -9.419 7.016 1.00 31.73 C +ATOM 1090 O SER A 84 32.480 -10.167 6.042 1.00 32.56 O +ATOM 1091 CB SER A 84 32.952 -10.655 9.221 1.00 33.28 C +ATOM 1092 OG SER A 84 31.922 -9.959 9.888 1.00 42.99 O +ATOM 1093 H SER A 84 33.966 -8.380 9.629 1.00 29.89 H +ATOM 1094 HA SER A 84 34.335 -10.429 7.630 1.00 33.65 H +ATOM 1095 HB3 SER A 84 33.706 -10.959 9.949 1.00 33.28 H +ATOM 1096 HB2 SER A 84 32.531 -11.570 8.802 1.00 33.28 H +ATOM 1097 HG SER A 84 32.322 -9.382 10.548 1.00 42.99 H +ATOM 1098 N VAL A 85 31.824 -8.306 7.184 1.00 32.27 N +ATOM 1099 CA VAL A 85 30.730 -7.941 6.274 1.00 30.87 C +ATOM 1100 C VAL A 85 31.093 -6.724 5.402 1.00 30.01 C +ATOM 1101 O VAL A 85 30.891 -6.804 4.192 1.00 32.23 O +ATOM 1102 CB VAL A 85 29.327 -7.758 6.969 1.00 32.16 C +ATOM 1103 CG1 VAL A 85 29.183 -8.501 8.313 1.00 32.40 C +ATOM 1104 CG2 VAL A 85 28.748 -6.334 7.115 1.00 32.73 C +ATOM 1105 H VAL A 85 31.936 -7.737 8.012 1.00 32.27 H +ATOM 1106 HA VAL A 85 30.580 -8.754 5.561 1.00 30.87 H +ATOM 1107 HB VAL A 85 28.630 -8.267 6.301 1.00 32.16 H +ATOM 1108 HG11 VAL A 85 28.132 -8.636 8.573 1.00 32.40 H +ATOM 1109 HG12 VAL A 85 29.644 -9.484 8.296 1.00 32.40 H +ATOM 1110 HG13 VAL A 85 29.642 -7.955 9.132 1.00 32.40 H +ATOM 1111 HG21 VAL A 85 27.754 -6.367 7.561 1.00 32.73 H +ATOM 1112 HG22 VAL A 85 29.368 -5.726 7.770 1.00 32.73 H +ATOM 1113 HG23 VAL A 85 28.641 -5.821 6.159 1.00 32.73 H +ATOM 1114 N VAL A 86 31.615 -5.632 5.994 1.00 28.37 N +ATOM 1115 CA VAL A 86 31.777 -4.360 5.277 1.00 30.45 C +ATOM 1116 C VAL A 86 33.036 -4.309 4.402 1.00 32.51 C +ATOM 1117 O VAL A 86 32.955 -3.773 3.301 1.00 30.96 O +ATOM 1118 CB VAL A 86 31.848 -3.126 6.215 1.00 29.71 C +ATOM 1119 CG1 VAL A 86 31.919 -1.776 5.462 1.00 30.36 C +ATOM 1120 CG2 VAL A 86 30.674 -3.082 7.193 1.00 30.48 C +ATOM 1121 H VAL A 86 31.796 -5.626 6.988 1.00 28.37 H +ATOM 1122 HA VAL A 86 30.912 -4.223 4.625 1.00 30.45 H +ATOM 1123 HB VAL A 86 32.753 -3.199 6.818 1.00 29.71 H +ATOM 1124 HG11 VAL A 86 31.834 -0.938 6.151 1.00 30.36 H +ATOM 1125 HG12 VAL A 86 32.862 -1.638 4.933 1.00 30.36 H +ATOM 1126 HG13 VAL A 86 31.109 -1.683 4.738 1.00 30.36 H +ATOM 1127 HG21 VAL A 86 30.776 -2.198 7.812 1.00 30.48 H +ATOM 1128 HG22 VAL A 86 29.715 -3.038 6.676 1.00 30.48 H +ATOM 1129 HG23 VAL A 86 30.669 -3.938 7.865 1.00 30.48 H +ATOM 1130 N CYS A 87 34.171 -4.829 4.898 1.00 33.65 N +ATOM 1131 CA CYS A 87 35.466 -4.747 4.221 1.00 34.56 C +ATOM 1132 C CYS A 87 35.499 -5.428 2.826 1.00 33.22 C +ATOM 1133 O CYS A 87 35.979 -4.778 1.898 1.00 32.37 O +ATOM 1134 CB CYS A 87 36.637 -5.135 5.153 1.00 37.83 C +ATOM 1135 SG CYS A 87 38.257 -4.723 4.441 1.00 49.64 S +ATOM 1136 H CYS A 87 34.171 -5.234 5.826 1.00 33.65 H +ATOM 1137 HA CYS A 87 35.602 -3.681 4.026 1.00 34.56 H +ATOM 1138 HB3 CYS A 87 36.620 -6.192 5.414 1.00 37.83 H +ATOM 1139 HB2 CYS A 87 36.552 -4.586 6.092 1.00 37.83 H +ATOM 1140 HG CYS A 87 38.187 -5.585 3.422 1.00 49.64 H +ATOM 1141 N PRO A 88 34.877 -6.623 2.651 1.00 32.21 N +ATOM 1142 CA PRO A 88 34.634 -7.211 1.317 1.00 33.69 C +ATOM 1143 C PRO A 88 33.717 -6.386 0.393 1.00 34.06 C +ATOM 1144 O PRO A 88 34.009 -6.288 -0.798 1.00 33.78 O +ATOM 1145 CB PRO A 88 34.022 -8.593 1.617 1.00 33.34 C +ATOM 1146 CG PRO A 88 34.480 -8.924 3.025 1.00 30.72 C +ATOM 1147 CD PRO A 88 34.482 -7.563 3.702 1.00 31.11 C +ATOM 1148 HA PRO A 88 35.606 -7.343 0.836 1.00 33.69 H +ATOM 1149 HB3 PRO A 88 34.328 -9.352 0.896 1.00 33.34 H +ATOM 1150 HB2 PRO A 88 32.931 -8.550 1.603 1.00 33.34 H +ATOM 1151 HG3 PRO A 88 35.497 -9.317 2.995 1.00 30.72 H +ATOM 1152 HG2 PRO A 88 33.849 -9.657 3.529 1.00 30.72 H +ATOM 1153 HD2 PRO A 88 33.478 -7.319 4.039 1.00 31.11 H +ATOM 1154 HD3 PRO A 88 35.141 -7.565 4.566 1.00 31.11 H +ATOM 1155 N ILE A 89 32.637 -5.810 0.955 1.00 33.67 N +ATOM 1156 CA ILE A 89 31.678 -4.963 0.237 1.00 32.79 C +ATOM 1157 C ILE A 89 32.318 -3.647 -0.250 1.00 33.05 C +ATOM 1158 O ILE A 89 32.088 -3.270 -1.398 1.00 33.90 O +ATOM 1159 CB ILE A 89 30.408 -4.655 1.095 1.00 34.37 C +ATOM 1160 CG1 ILE A 89 29.592 -5.944 1.343 1.00 34.88 C +ATOM 1161 CG2 ILE A 89 29.476 -3.569 0.514 1.00 31.66 C +ATOM 1162 CD1 ILE A 89 28.557 -5.817 2.473 1.00 40.21 C +ATOM 1163 H ILE A 89 32.465 -5.932 1.943 1.00 33.67 H +ATOM 1164 HA ILE A 89 31.357 -5.514 -0.649 1.00 32.79 H +ATOM 1165 HB ILE A 89 30.747 -4.296 2.066 1.00 34.37 H +ATOM 1166 HG13 ILE A 89 30.254 -6.776 1.582 1.00 34.88 H +ATOM 1167 HG12 ILE A 89 29.083 -6.232 0.423 1.00 34.88 H +ATOM 1168 HG21 ILE A 89 28.588 -3.427 1.130 1.00 31.66 H +ATOM 1169 HG22 ILE A 89 29.954 -2.592 0.442 1.00 31.66 H +ATOM 1170 HG23 ILE A 89 29.140 -3.861 -0.479 1.00 31.66 H +ATOM 1171 HD11 ILE A 89 28.344 -6.790 2.915 1.00 40.21 H +ATOM 1172 HD12 ILE A 89 28.909 -5.164 3.271 1.00 40.21 H +ATOM 1173 HD13 ILE A 89 27.615 -5.412 2.109 1.00 40.21 H +ATOM 1174 N LEU A 90 33.136 -3.007 0.606 1.00 34.40 N +ATOM 1175 CA LEU A 90 33.893 -1.797 0.292 1.00 36.12 C +ATOM 1176 C LEU A 90 34.934 -2.024 -0.812 1.00 36.86 C +ATOM 1177 O LEU A 90 35.085 -1.142 -1.647 1.00 35.34 O +ATOM 1178 CB LEU A 90 34.528 -1.192 1.569 1.00 35.83 C +ATOM 1179 CG LEU A 90 35.307 0.134 1.353 1.00 37.20 C +ATOM 1180 CD1 LEU A 90 34.436 1.251 0.742 1.00 39.93 C +ATOM 1181 CD2 LEU A 90 36.004 0.598 2.643 1.00 37.31 C +ATOM 1182 H LEU A 90 33.258 -3.378 1.541 1.00 34.40 H +ATOM 1183 HA LEU A 90 33.165 -1.083 -0.095 1.00 36.12 H +ATOM 1184 HB3 LEU A 90 35.196 -1.934 2.010 1.00 35.83 H +ATOM 1185 HB2 LEU A 90 33.744 -1.024 2.310 1.00 35.83 H +ATOM 1186 HG LEU A 90 36.119 -0.063 0.652 1.00 37.20 H +ATOM 1187 HD11 LEU A 90 34.560 2.196 1.266 1.00 39.93 H +ATOM 1188 HD12 LEU A 90 34.701 1.426 -0.301 1.00 39.93 H +ATOM 1189 HD13 LEU A 90 33.373 1.013 0.776 1.00 39.93 H +ATOM 1190 HD21 LEU A 90 36.930 1.130 2.418 1.00 37.31 H +ATOM 1191 HD22 LEU A 90 35.375 1.265 3.234 1.00 37.31 H +ATOM 1192 HD23 LEU A 90 36.270 -0.252 3.270 1.00 37.31 H +ATOM 1193 N ASP A 91 35.598 -3.193 -0.840 1.00 36.65 N +ATOM 1194 CA ASP A 91 36.536 -3.564 -1.910 1.00 39.50 C +ATOM 1195 C ASP A 91 35.874 -3.637 -3.290 1.00 39.38 C +ATOM 1196 O ASP A 91 36.474 -3.162 -4.251 1.00 39.21 O +ATOM 1197 CB ASP A 91 37.327 -4.862 -1.621 1.00 39.23 C +ATOM 1198 CG ASP A 91 38.243 -4.809 -0.389 1.00 42.38 C +ATOM 1199 OD1 ASP A 91 38.630 -3.692 0.019 1.00 41.38 O +ATOM 1200 OD2 ASP A 91 38.656 -5.900 0.061 1.00 43.09 O1- +ATOM 1201 H ASP A 91 35.449 -3.878 -0.112 1.00 36.65 H +ATOM 1202 HA ASP A 91 37.255 -2.745 -1.986 1.00 39.50 H +ATOM 1203 HB3 ASP A 91 37.948 -5.118 -2.481 1.00 39.23 H +ATOM 1204 HB2 ASP A 91 36.626 -5.687 -1.482 1.00 39.23 H +ATOM 1205 N GLU A 92 34.636 -4.153 -3.357 1.00 38.83 N +ATOM 1206 CA GLU A 92 33.822 -4.130 -4.570 1.00 39.48 C +ATOM 1207 C GLU A 92 33.406 -2.704 -4.992 1.00 38.74 C +ATOM 1208 O GLU A 92 33.427 -2.412 -6.187 1.00 36.80 O +ATOM 1209 CB GLU A 92 32.677 -5.155 -4.437 1.00 41.28 C +ATOM 1210 CG GLU A 92 31.664 -5.155 -5.606 1.00 42.07 C +ATOM 1211 CD GLU A 92 30.783 -6.408 -5.738 1.00 44.04 C +ATOM 1212 OE1 GLU A 92 31.165 -7.481 -5.219 1.00 41.66 O +ATOM 1213 OE2 GLU A 92 29.716 -6.276 -6.378 1.00 43.65 O1- +ATOM 1214 H GLU A 92 34.199 -4.522 -2.524 1.00 38.83 H +ATOM 1215 HA GLU A 92 34.456 -4.501 -5.378 1.00 39.48 H +ATOM 1216 HB3 GLU A 92 32.142 -5.003 -3.499 1.00 41.28 H +ATOM 1217 HB2 GLU A 92 33.151 -6.134 -4.349 1.00 41.28 H +ATOM 1218 HG3 GLU A 92 32.197 -5.039 -6.550 1.00 42.07 H +ATOM 1219 HG2 GLU A 92 31.013 -4.287 -5.499 1.00 42.07 H +ATOM 1220 N VAL A 93 33.139 -1.814 -4.019 1.00 37.58 N +ATOM 1221 CA VAL A 93 32.923 -0.380 -4.251 1.00 39.39 C +ATOM 1222 C VAL A 93 34.175 0.314 -4.837 1.00 39.94 C +ATOM 1223 O VAL A 93 34.025 1.084 -5.783 1.00 38.57 O +ATOM 1224 CB VAL A 93 32.449 0.365 -2.966 1.00 39.78 C +ATOM 1225 CG1 VAL A 93 32.354 1.898 -3.088 1.00 38.88 C +ATOM 1226 CG2 VAL A 93 31.106 -0.188 -2.478 1.00 39.30 C +ATOM 1227 H VAL A 93 33.145 -2.116 -3.054 1.00 37.58 H +ATOM 1228 HA VAL A 93 32.130 -0.298 -4.994 1.00 39.39 H +ATOM 1229 HB VAL A 93 33.162 0.174 -2.172 1.00 39.78 H +ATOM 1230 HG11 VAL A 93 31.929 2.340 -2.186 1.00 38.88 H +ATOM 1231 HG12 VAL A 93 33.328 2.363 -3.237 1.00 38.88 H +ATOM 1232 HG13 VAL A 93 31.716 2.176 -3.922 1.00 38.88 H +ATOM 1233 HG21 VAL A 93 30.928 0.081 -1.439 1.00 39.30 H +ATOM 1234 HG22 VAL A 93 30.281 0.183 -3.087 1.00 39.30 H +ATOM 1235 HG23 VAL A 93 31.073 -1.272 -2.519 1.00 39.30 H +ATOM 1236 N ILE A 94 35.381 -0.018 -4.332 1.00 39.41 N +ATOM 1237 CA ILE A 94 36.664 0.464 -4.868 1.00 41.12 C +ATOM 1238 C ILE A 94 36.959 -0.065 -6.295 1.00 42.53 C +ATOM 1239 O ILE A 94 37.577 0.656 -7.077 1.00 42.63 O +ATOM 1240 CB ILE A 94 37.881 0.141 -3.934 1.00 41.77 C +ATOM 1241 CG1 ILE A 94 37.738 0.693 -2.491 1.00 41.96 C +ATOM 1242 CG2 ILE A 94 39.247 0.594 -4.501 1.00 41.60 C +ATOM 1243 CD1 ILE A 94 37.118 2.090 -2.355 1.00 42.93 C +ATOM 1244 H ILE A 94 35.433 -0.655 -3.548 1.00 39.41 H +ATOM 1245 HA ILE A 94 36.581 1.547 -4.959 1.00 41.12 H +ATOM 1246 HB ILE A 94 37.938 -0.944 -3.835 1.00 41.77 H +ATOM 1247 HG13 ILE A 94 38.703 0.678 -1.982 1.00 41.96 H +ATOM 1248 HG12 ILE A 94 37.141 0.003 -1.907 1.00 41.96 H +ATOM 1249 HG21 ILE A 94 40.053 0.409 -3.791 1.00 41.60 H +ATOM 1250 HG22 ILE A 94 39.524 0.059 -5.409 1.00 41.60 H +ATOM 1251 HG23 ILE A 94 39.249 1.660 -4.727 1.00 41.60 H +ATOM 1252 HD11 ILE A 94 37.408 2.554 -1.412 1.00 42.93 H +ATOM 1253 HD12 ILE A 94 37.428 2.758 -3.160 1.00 42.93 H +ATOM 1254 HD13 ILE A 94 36.031 2.027 -2.368 1.00 42.93 H +ATOM 1255 N MET A 95 36.451 -1.262 -6.647 1.00 42.42 N +ATOM 1256 CA MET A 95 36.461 -1.797 -8.018 1.00 44.90 C +ATOM 1257 C MET A 95 35.496 -1.076 -8.985 1.00 45.13 C +ATOM 1258 O MET A 95 35.525 -1.380 -10.177 1.00 44.37 O +ATOM 1259 CB MET A 95 36.185 -3.314 -8.011 1.00 46.53 C +ATOM 1260 CG MET A 95 37.313 -4.150 -7.394 1.00 50.85 C +ATOM 1261 SD MET A 95 36.937 -5.920 -7.288 1.00 55.62 S +ATOM 1262 CE MET A 95 37.130 -6.386 -9.029 1.00 55.21 C +ATOM 1263 H MET A 95 35.964 -1.817 -5.956 1.00 42.42 H +ATOM 1264 HA MET A 95 37.461 -1.646 -8.428 1.00 44.90 H +ATOM 1265 HB3 MET A 95 36.038 -3.661 -9.034 1.00 46.53 H +ATOM 1266 HB2 MET A 95 35.251 -3.531 -7.499 1.00 46.53 H +ATOM 1267 HG3 MET A 95 37.548 -3.798 -6.393 1.00 50.85 H +ATOM 1268 HG2 MET A 95 38.227 -4.026 -7.975 1.00 50.85 H +ATOM 1269 HE1 MET A 95 36.999 -7.462 -9.143 1.00 55.21 H +ATOM 1270 HE2 MET A 95 36.388 -5.885 -9.650 1.00 55.21 H +ATOM 1271 HE3 MET A 95 38.124 -6.120 -9.389 1.00 55.21 H +ATOM 1272 N GLY A 96 34.701 -0.117 -8.485 1.00 43.95 N +ATOM 1273 CA GLY A 96 33.850 0.740 -9.300 1.00 42.59 C +ATOM 1274 C GLY A 96 32.426 0.183 -9.428 1.00 42.57 C +ATOM 1275 O GLY A 96 31.765 0.478 -10.423 1.00 41.48 O +ATOM 1276 H GLY A 96 34.728 0.080 -7.494 1.00 43.95 H +ATOM 1277 HA3 GLY A 96 34.283 0.899 -10.288 1.00 42.59 H +ATOM 1278 HA2 GLY A 96 33.806 1.714 -8.817 1.00 42.59 H +ATOM 1279 N TYR A 97 31.959 -0.616 -8.453 1.00 41.65 N +ATOM 1280 CA TYR A 97 30.594 -1.150 -8.403 1.00 41.71 C +ATOM 1281 C TYR A 97 29.727 -0.365 -7.413 1.00 38.76 C +ATOM 1282 O TYR A 97 30.233 0.370 -6.562 1.00 37.69 O +ATOM 1283 CB TYR A 97 30.624 -2.643 -8.016 1.00 45.44 C +ATOM 1284 CG TYR A 97 31.041 -3.583 -9.133 1.00 52.18 C +ATOM 1285 CD1 TYR A 97 32.369 -3.594 -9.610 1.00 54.66 C +ATOM 1286 CD2 TYR A 97 30.085 -4.446 -9.708 1.00 53.53 C +ATOM 1287 CE1 TYR A 97 32.728 -4.436 -10.680 1.00 57.85 C +ATOM 1288 CE2 TYR A 97 30.447 -5.296 -10.769 1.00 57.11 C +ATOM 1289 CZ TYR A 97 31.765 -5.284 -11.263 1.00 58.28 C +ATOM 1290 OH TYR A 97 32.105 -6.094 -12.307 1.00 60.52 O +ATOM 1291 H TYR A 97 32.551 -0.842 -7.666 1.00 41.65 H +ATOM 1292 HA TYR A 97 30.123 -1.070 -9.385 1.00 41.71 H +ATOM 1293 HB3 TYR A 97 29.632 -2.965 -7.695 1.00 45.44 H +ATOM 1294 HB2 TYR A 97 31.253 -2.798 -7.149 1.00 45.44 H +ATOM 1295 HD1 TYR A 97 33.115 -2.953 -9.166 1.00 54.66 H +ATOM 1296 HD2 TYR A 97 29.068 -4.456 -9.345 1.00 53.53 H +ATOM 1297 HE1 TYR A 97 33.744 -4.428 -11.046 1.00 57.85 H +ATOM 1298 HE2 TYR A 97 29.708 -5.950 -11.210 1.00 57.11 H +ATOM 1299 HH TYR A 97 33.026 -6.009 -12.564 1.00 60.52 H +ATOM 1300 N ASN A 98 28.411 -0.575 -7.554 1.00 36.08 N +ATOM 1301 CA ASN A 98 27.384 -0.057 -6.660 1.00 33.17 C +ATOM 1302 C ASN A 98 27.034 -1.142 -5.638 1.00 29.96 C +ATOM 1303 O ASN A 98 26.784 -2.287 -6.022 1.00 27.65 O +ATOM 1304 CB ASN A 98 26.144 0.359 -7.479 1.00 34.52 C +ATOM 1305 CG ASN A 98 26.423 1.507 -8.460 1.00 37.68 C +ATOM 1306 OD1 ASN A 98 27.249 2.378 -8.202 1.00 37.20 O +ATOM 1307 ND2 ASN A 98 25.727 1.517 -9.596 1.00 36.60 N +ATOM 1308 H ASN A 98 28.085 -1.200 -8.278 1.00 36.08 H +ATOM 1309 HA ASN A 98 27.764 0.825 -6.148 1.00 33.17 H +ATOM 1310 HB3 ASN A 98 25.353 0.691 -6.805 1.00 34.52 H +ATOM 1311 HB2 ASN A 98 25.747 -0.499 -8.024 1.00 34.52 H +ATOM 1312 HD22 ASN A 98 25.873 2.254 -10.270 1.00 36.60 H +ATOM 1313 HD21 ASN A 98 25.081 0.767 -9.813 1.00 36.60 H +ATOM 1314 N CYS A 99 27.016 -0.749 -4.358 1.00 28.42 N +ATOM 1315 CA CYS A 99 26.696 -1.611 -3.225 1.00 26.99 C +ATOM 1316 C CYS A 99 25.673 -0.908 -2.318 1.00 24.43 C +ATOM 1317 O CYS A 99 25.582 0.320 -2.325 1.00 23.39 O +ATOM 1318 CB CYS A 99 27.955 -1.985 -2.425 1.00 26.76 C +ATOM 1319 SG CYS A 99 29.011 -3.136 -3.354 1.00 30.41 S +ATOM 1320 H CYS A 99 27.243 0.211 -4.130 1.00 28.42 H +ATOM 1321 HA CYS A 99 26.241 -2.526 -3.591 1.00 26.99 H +ATOM 1322 HB3 CYS A 99 27.680 -2.458 -1.483 1.00 26.76 H +ATOM 1323 HB2 CYS A 99 28.525 -1.090 -2.189 1.00 26.76 H +ATOM 1324 HG CYS A 99 30.010 -3.165 -2.466 1.00 30.41 H +ATOM 1325 N THR A 100 24.921 -1.703 -1.543 1.00 23.88 N +ATOM 1326 CA THR A 100 23.961 -1.219 -0.553 1.00 23.96 C +ATOM 1327 C THR A 100 23.948 -2.173 0.649 1.00 24.20 C +ATOM 1328 O THR A 100 24.034 -3.385 0.467 1.00 24.93 O +ATOM 1329 CB THR A 100 22.521 -1.117 -1.133 1.00 21.66 C +ATOM 1330 OG1 THR A 100 22.493 -0.090 -2.101 1.00 23.67 O +ATOM 1331 CG2 THR A 100 21.398 -0.804 -0.122 1.00 20.28 C +ATOM 1332 H THR A 100 25.014 -2.708 -1.619 1.00 23.88 H +ATOM 1333 HA THR A 100 24.284 -0.238 -0.213 1.00 23.96 H +ATOM 1334 HB THR A 100 22.274 -2.046 -1.648 1.00 21.66 H +ATOM 1335 HG1 THR A 100 21.640 -0.127 -2.550 1.00 23.67 H +ATOM 1336 HG21 THR A 100 20.452 -0.608 -0.628 1.00 20.28 H +ATOM 1337 HG22 THR A 100 21.223 -1.636 0.560 1.00 20.28 H +ATOM 1338 HG23 THR A 100 21.637 0.074 0.478 1.00 20.28 H +ATOM 1339 N ILE A 101 23.827 -1.612 1.859 1.00 23.51 N +ATOM 1340 CA ILE A 101 23.663 -2.377 3.089 1.00 21.26 C +ATOM 1341 C ILE A 101 22.478 -1.766 3.854 1.00 20.88 C +ATOM 1342 O ILE A 101 22.540 -0.599 4.238 1.00 21.37 O +ATOM 1343 CB ILE A 101 24.924 -2.353 4.005 1.00 21.03 C +ATOM 1344 CG1 ILE A 101 26.227 -2.696 3.242 1.00 21.50 C +ATOM 1345 CG2 ILE A 101 24.751 -3.311 5.208 1.00 19.72 C +ATOM 1346 CD1 ILE A 101 27.506 -2.553 4.084 1.00 22.58 C +ATOM 1347 H ILE A 101 23.786 -0.604 1.949 1.00 23.51 H +ATOM 1348 HA ILE A 101 23.433 -3.418 2.864 1.00 21.26 H +ATOM 1349 HB ILE A 101 25.049 -1.341 4.391 1.00 21.03 H +ATOM 1350 HG13 ILE A 101 26.338 -2.050 2.372 1.00 21.50 H +ATOM 1351 HG12 ILE A 101 26.162 -3.711 2.852 1.00 21.50 H +ATOM 1352 HG21 ILE A 101 25.608 -3.268 5.879 1.00 19.72 H +ATOM 1353 HG22 ILE A 101 23.874 -3.074 5.811 1.00 19.72 H +ATOM 1354 HG23 ILE A 101 24.646 -4.344 4.877 1.00 19.72 H +ATOM 1355 HD11 ILE A 101 28.371 -2.365 3.448 1.00 22.58 H +ATOM 1356 HD12 ILE A 101 27.433 -1.726 4.791 1.00 22.58 H +ATOM 1357 HD13 ILE A 101 27.708 -3.461 4.651 1.00 22.58 H +ATOM 1358 N PHE A 102 21.428 -2.574 4.056 1.00 20.90 N +ATOM 1359 CA PHE A 102 20.280 -2.239 4.896 1.00 21.42 C +ATOM 1360 C PHE A 102 20.543 -2.625 6.359 1.00 22.24 C +ATOM 1361 O PHE A 102 21.201 -3.632 6.615 1.00 22.50 O +ATOM 1362 CB PHE A 102 19.023 -2.974 4.390 1.00 21.24 C +ATOM 1363 CG PHE A 102 18.434 -2.482 3.079 1.00 24.65 C +ATOM 1364 CD1 PHE A 102 17.545 -1.388 3.071 1.00 24.59 C +ATOM 1365 CD2 PHE A 102 18.848 -3.032 1.847 1.00 23.12 C +ATOM 1366 CE1 PHE A 102 17.011 -0.931 1.874 1.00 27.89 C +ATOM 1367 CE2 PHE A 102 18.315 -2.550 0.657 1.00 26.02 C +ATOM 1368 CZ PHE A 102 17.391 -1.513 0.671 1.00 25.24 C +ATOM 1369 H PHE A 102 21.449 -3.517 3.690 1.00 20.90 H +ATOM 1370 HA PHE A 102 20.086 -1.169 4.849 1.00 21.42 H +ATOM 1371 HB3 PHE A 102 18.231 -2.908 5.138 1.00 21.24 H +ATOM 1372 HB2 PHE A 102 19.243 -4.035 4.295 1.00 21.24 H +ATOM 1373 HD1 PHE A 102 17.263 -0.913 3.999 1.00 24.59 H +ATOM 1374 HD2 PHE A 102 19.564 -3.840 1.828 1.00 23.12 H +ATOM 1375 HE1 PHE A 102 16.305 -0.114 1.877 1.00 27.89 H +ATOM 1376 HE2 PHE A 102 18.617 -2.981 -0.285 1.00 26.02 H +ATOM 1377 HZ PHE A 102 16.978 -1.148 -0.258 1.00 25.24 H +ATOM 1378 N ALA A 103 19.945 -1.860 7.281 1.00 19.47 N +ATOM 1379 CA ALA A 103 19.755 -2.227 8.677 1.00 20.05 C +ATOM 1380 C ALA A 103 18.246 -2.264 8.921 1.00 19.29 C +ATOM 1381 O ALA A 103 17.575 -1.250 8.726 1.00 18.27 O +ATOM 1382 CB ALA A 103 20.464 -1.237 9.610 1.00 18.35 C +ATOM 1383 H ALA A 103 19.478 -1.012 6.990 1.00 19.47 H +ATOM 1384 HA ALA A 103 20.173 -3.213 8.870 1.00 20.05 H +ATOM 1385 HB1 ALA A 103 20.191 -1.415 10.649 1.00 18.35 H +ATOM 1386 HB2 ALA A 103 21.543 -1.363 9.545 1.00 18.35 H +ATOM 1387 HB3 ALA A 103 20.232 -0.200 9.375 1.00 18.35 H +ATOM 1388 N TYR A 104 17.754 -3.448 9.308 1.00 17.95 N +ATOM 1389 CA TYR A 104 16.345 -3.736 9.559 1.00 19.33 C +ATOM 1390 C TYR A 104 16.200 -4.308 10.975 1.00 20.55 C +ATOM 1391 O TYR A 104 17.114 -4.974 11.451 1.00 22.06 O +ATOM 1392 CB TYR A 104 15.845 -4.732 8.486 1.00 18.75 C +ATOM 1393 CG TYR A 104 14.369 -5.088 8.581 1.00 19.21 C +ATOM 1394 CD1 TYR A 104 13.953 -6.183 9.364 1.00 21.30 C +ATOM 1395 CD2 TYR A 104 13.402 -4.303 7.921 1.00 20.16 C +ATOM 1396 CE1 TYR A 104 12.582 -6.462 9.515 1.00 21.55 C +ATOM 1397 CE2 TYR A 104 12.031 -4.588 8.061 1.00 20.84 C +ATOM 1398 CZ TYR A 104 11.621 -5.671 8.861 1.00 22.27 C +ATOM 1399 OH TYR A 104 10.296 -5.965 8.993 1.00 22.91 O +ATOM 1400 H TYR A 104 18.392 -4.217 9.471 1.00 17.95 H +ATOM 1401 HA TYR A 104 15.759 -2.819 9.496 1.00 19.33 H +ATOM 1402 HB3 TYR A 104 16.428 -5.655 8.536 1.00 18.75 H +ATOM 1403 HB2 TYR A 104 16.032 -4.326 7.491 1.00 18.75 H +ATOM 1404 HD1 TYR A 104 14.685 -6.793 9.871 1.00 21.30 H +ATOM 1405 HD2 TYR A 104 13.708 -3.467 7.319 1.00 20.16 H +ATOM 1406 HE1 TYR A 104 12.267 -7.288 10.129 1.00 21.55 H +ATOM 1407 HE2 TYR A 104 11.300 -3.979 7.551 1.00 20.84 H +ATOM 1408 HH TYR A 104 9.725 -5.398 8.471 1.00 22.91 H +ATOM 1409 N GLY A 105 15.040 -4.081 11.605 1.00 19.26 N +ATOM 1410 CA GLY A 105 14.725 -4.644 12.911 1.00 21.52 C +ATOM 1411 C GLY A 105 13.948 -3.638 13.755 1.00 20.28 C +ATOM 1412 O GLY A 105 13.716 -2.494 13.358 1.00 18.68 O +ATOM 1413 H GLY A 105 14.335 -3.496 11.171 1.00 19.26 H +ATOM 1414 HA3 GLY A 105 15.626 -4.913 13.463 1.00 21.52 H +ATOM 1415 HA2 GLY A 105 14.135 -5.550 12.776 1.00 21.52 H +ATOM 1416 N GLN A 106 13.532 -4.107 14.940 1.00 21.44 N +ATOM 1417 CA GLN A 106 12.794 -3.351 15.948 1.00 20.84 C +ATOM 1418 C GLN A 106 13.602 -2.165 16.513 1.00 21.07 C +ATOM 1419 O GLN A 106 14.830 -2.189 16.500 1.00 21.08 O +ATOM 1420 CB GLN A 106 12.285 -4.341 17.023 1.00 22.65 C +ATOM 1421 CG GLN A 106 11.686 -3.716 18.302 1.00 25.55 C +ATOM 1422 CD GLN A 106 11.212 -4.756 19.314 1.00 28.83 C +ATOM 1423 OE1 GLN A 106 11.800 -5.827 19.446 1.00 30.01 O +ATOM 1424 NE2 GLN A 106 10.160 -4.423 20.062 1.00 30.80 N +ATOM 1425 H GLN A 106 13.737 -5.069 15.184 1.00 21.44 H +ATOM 1426 HA GLN A 106 11.921 -2.955 15.433 1.00 20.84 H +ATOM 1427 HB3 GLN A 106 13.097 -5.003 17.309 1.00 22.65 H +ATOM 1428 HB2 GLN A 106 11.533 -4.986 16.564 1.00 22.65 H +ATOM 1429 HG3 GLN A 106 10.860 -3.055 18.037 1.00 25.55 H +ATOM 1430 HG2 GLN A 106 12.430 -3.114 18.820 1.00 25.55 H +ATOM 1431 HE22 GLN A 106 9.782 -5.072 20.738 1.00 30.80 H +ATOM 1432 HE21 GLN A 106 9.710 -3.527 19.937 1.00 30.80 H +ATOM 1433 N THR A 107 12.892 -1.140 17.001 1.00 22.00 N +ATOM 1434 CA THR A 107 13.447 0.056 17.620 1.00 22.73 C +ATOM 1435 C THR A 107 14.171 -0.302 18.923 1.00 24.87 C +ATOM 1436 O THR A 107 13.597 -0.965 19.788 1.00 22.44 O +ATOM 1437 CB THR A 107 12.342 1.100 17.933 1.00 22.42 C +ATOM 1438 OG1 THR A 107 11.751 1.514 16.718 1.00 21.89 O +ATOM 1439 CG2 THR A 107 12.816 2.371 18.664 1.00 22.99 C +ATOM 1440 H THR A 107 11.882 -1.188 16.966 1.00 22.00 H +ATOM 1441 HA THR A 107 14.161 0.483 16.918 1.00 22.73 H +ATOM 1442 HB THR A 107 11.556 0.631 18.527 1.00 22.42 H +ATOM 1443 HG1 THR A 107 10.878 1.871 16.912 1.00 21.89 H +ATOM 1444 HG21 THR A 107 12.005 3.093 18.758 1.00 22.99 H +ATOM 1445 HG22 THR A 107 13.164 2.156 19.675 1.00 22.99 H +ATOM 1446 HG23 THR A 107 13.633 2.857 18.128 1.00 22.99 H +ATOM 1447 N GLY A 108 15.426 0.146 19.009 1.00 25.38 N +ATOM 1448 CA GLY A 108 16.298 -0.095 20.144 1.00 25.41 C +ATOM 1449 C GLY A 108 17.017 -1.451 20.065 1.00 23.92 C +ATOM 1450 O GLY A 108 17.517 -1.888 21.099 1.00 21.87 O +ATOM 1451 H GLY A 108 15.804 0.707 18.251 1.00 25.38 H +ATOM 1452 HA3 GLY A 108 15.743 -0.023 21.081 1.00 25.41 H +ATOM 1453 HA2 GLY A 108 17.032 0.707 20.154 1.00 25.41 H +ATOM 1454 N THR A 109 17.076 -2.123 18.898 1.00 21.42 N +ATOM 1455 CA THR A 109 17.781 -3.405 18.737 1.00 22.55 C +ATOM 1456 C THR A 109 19.199 -3.267 18.150 1.00 24.86 C +ATOM 1457 O THR A 109 19.950 -4.237 18.261 1.00 23.18 O +ATOM 1458 CB THR A 109 16.997 -4.425 17.881 1.00 25.44 C +ATOM 1459 OG1 THR A 109 16.842 -4.014 16.541 1.00 25.10 O +ATOM 1460 CG2 THR A 109 15.633 -4.772 18.479 1.00 23.33 C +ATOM 1461 H THR A 109 16.676 -1.715 18.062 1.00 21.42 H +ATOM 1462 HA THR A 109 17.907 -3.876 19.711 1.00 22.55 H +ATOM 1463 HB THR A 109 17.569 -5.351 17.845 1.00 25.44 H +ATOM 1464 HG1 THR A 109 16.186 -3.307 16.514 1.00 25.10 H +ATOM 1465 HG21 THR A 109 15.155 -5.552 17.892 1.00 23.33 H +ATOM 1466 HG22 THR A 109 15.742 -5.149 19.493 1.00 23.33 H +ATOM 1467 HG23 THR A 109 14.966 -3.911 18.523 1.00 23.33 H +ATOM 1468 N GLY A 110 19.571 -2.092 17.614 1.00 22.69 N +ATOM 1469 CA GLY A 110 20.961 -1.794 17.276 1.00 22.97 C +ATOM 1470 C GLY A 110 21.173 -1.403 15.813 1.00 23.46 C +ATOM 1471 O GLY A 110 22.295 -1.577 15.341 1.00 22.88 O +ATOM 1472 H GLY A 110 18.894 -1.346 17.498 1.00 22.69 H +ATOM 1473 HA3 GLY A 110 21.636 -2.620 17.506 1.00 22.97 H +ATOM 1474 HA2 GLY A 110 21.290 -0.967 17.897 1.00 22.97 H +ATOM 1475 N LYS A 111 20.159 -0.894 15.085 1.00 19.23 N +ATOM 1476 CA LYS A 111 20.320 -0.437 13.696 1.00 20.76 C +ATOM 1477 C LYS A 111 21.287 0.753 13.576 1.00 20.44 C +ATOM 1478 O LYS A 111 22.252 0.649 12.821 1.00 21.60 O +ATOM 1479 CB LYS A 111 18.975 -0.072 13.046 1.00 18.15 C +ATOM 1480 CG LYS A 111 17.980 -1.229 12.902 1.00 21.24 C +ATOM 1481 CD LYS A 111 16.680 -0.802 12.193 1.00 20.68 C +ATOM 1482 CE LYS A 111 15.860 0.293 12.895 1.00 18.44 C +ATOM 1483 NZ LYS A 111 15.512 -0.068 14.276 1.00 18.27 N1+ +ATOM 1484 H LYS A 111 19.254 -0.729 15.516 1.00 19.23 H +ATOM 1485 HA LYS A 111 20.746 -1.266 13.128 1.00 20.76 H +ATOM 1486 HB3 LYS A 111 19.175 0.306 12.045 1.00 18.15 H +ATOM 1487 HB2 LYS A 111 18.514 0.747 13.593 1.00 18.15 H +ATOM 1488 HG3 LYS A 111 17.754 -1.645 13.883 1.00 21.24 H +ATOM 1489 HG2 LYS A 111 18.443 -2.037 12.336 1.00 21.24 H +ATOM 1490 HD3 LYS A 111 16.047 -1.674 12.051 1.00 20.68 H +ATOM 1491 HD2 LYS A 111 16.922 -0.454 11.189 1.00 20.68 H +ATOM 1492 HE3 LYS A 111 14.929 0.454 12.353 1.00 18.44 H +ATOM 1493 HE2 LYS A 111 16.395 1.242 12.901 1.00 18.44 H +ATOM 1494 HZ1 LYS A 111 16.356 -0.186 14.826 1.00 18.27 H +ATOM 1495 HZ2 LYS A 111 14.963 0.677 14.684 1.00 18.27 H +ATOM 1496 HZ3 LYS A 111 14.983 -0.929 14.281 1.00 18.27 H +ATOM 1497 N THR A 112 21.037 1.827 14.348 1.00 20.23 N +ATOM 1498 CA THR A 112 21.883 3.023 14.425 1.00 21.91 C +ATOM 1499 C THR A 112 23.283 2.719 14.991 1.00 21.96 C +ATOM 1500 O THR A 112 24.266 3.230 14.460 1.00 20.36 O +ATOM 1501 CB THR A 112 21.250 4.137 15.307 1.00 23.15 C +ATOM 1502 OG1 THR A 112 19.962 4.458 14.824 1.00 24.85 O +ATOM 1503 CG2 THR A 112 22.054 5.448 15.386 1.00 22.97 C +ATOM 1504 H THR A 112 20.204 1.838 14.930 1.00 20.23 H +ATOM 1505 HA THR A 112 22.007 3.408 13.411 1.00 21.91 H +ATOM 1506 HB THR A 112 21.113 3.767 16.322 1.00 23.15 H +ATOM 1507 HG1 THR A 112 19.384 3.697 14.974 1.00 24.85 H +ATOM 1508 HG21 THR A 112 21.507 6.208 15.946 1.00 22.97 H +ATOM 1509 HG22 THR A 112 23.015 5.318 15.883 1.00 22.97 H +ATOM 1510 HG23 THR A 112 22.242 5.845 14.389 1.00 22.97 H +ATOM 1511 N PHE A 113 23.354 1.861 16.023 1.00 22.76 N +ATOM 1512 CA PHE A 113 24.592 1.384 16.635 1.00 23.80 C +ATOM 1513 C PHE A 113 25.478 0.622 15.637 1.00 21.95 C +ATOM 1514 O PHE A 113 26.684 0.843 15.619 1.00 22.14 O +ATOM 1515 CB PHE A 113 24.269 0.536 17.883 1.00 23.71 C +ATOM 1516 CG PHE A 113 25.481 0.078 18.677 1.00 26.76 C +ATOM 1517 CD1 PHE A 113 26.063 0.946 19.624 1.00 27.02 C +ATOM 1518 CD2 PHE A 113 26.141 -1.129 18.359 1.00 26.47 C +ATOM 1519 CE1 PHE A 113 27.228 0.578 20.283 1.00 27.82 C +ATOM 1520 CE2 PHE A 113 27.308 -1.475 19.024 1.00 29.17 C +ATOM 1521 CZ PHE A 113 27.843 -0.632 19.988 1.00 28.08 C +ATOM 1522 H PHE A 113 22.490 1.526 16.442 1.00 22.76 H +ATOM 1523 HA PHE A 113 25.145 2.267 16.963 1.00 23.80 H +ATOM 1524 HB3 PHE A 113 23.679 -0.338 17.603 1.00 23.71 H +ATOM 1525 HB2 PHE A 113 23.637 1.118 18.554 1.00 23.71 H +ATOM 1526 HD1 PHE A 113 25.601 1.897 19.842 1.00 27.02 H +ATOM 1527 HD2 PHE A 113 25.737 -1.787 17.604 1.00 26.47 H +ATOM 1528 HE1 PHE A 113 27.658 1.237 21.023 1.00 27.82 H +ATOM 1529 HE2 PHE A 113 27.800 -2.408 18.796 1.00 29.17 H +ATOM 1530 HZ PHE A 113 28.744 -0.921 20.505 1.00 28.08 H +ATOM 1531 N THR A 114 24.870 -0.227 14.795 1.00 21.64 N +ATOM 1532 CA THR A 114 25.576 -0.934 13.733 1.00 22.49 C +ATOM 1533 C THR A 114 26.054 0.029 12.631 1.00 24.03 C +ATOM 1534 O THR A 114 27.251 0.055 12.356 1.00 20.85 O +ATOM 1535 CB THR A 114 24.714 -2.051 13.092 1.00 24.26 C +ATOM 1536 OG1 THR A 114 24.377 -3.012 14.073 1.00 21.97 O +ATOM 1537 CG2 THR A 114 25.388 -2.795 11.930 1.00 22.94 C +ATOM 1538 H THR A 114 23.869 -0.367 14.852 1.00 21.64 H +ATOM 1539 HA THR A 114 26.462 -1.396 14.170 1.00 22.49 H +ATOM 1540 HB THR A 114 23.774 -1.629 12.732 1.00 24.26 H +ATOM 1541 HG1 THR A 114 23.727 -2.617 14.666 1.00 21.97 H +ATOM 1542 HG21 THR A 114 24.766 -3.619 11.597 1.00 22.94 H +ATOM 1543 HG22 THR A 114 25.531 -2.149 11.065 1.00 22.94 H +ATOM 1544 HG23 THR A 114 26.358 -3.198 12.221 1.00 22.94 H +ATOM 1545 N MET A 115 25.125 0.805 12.046 1.00 23.61 N +ATOM 1546 CA MET A 115 25.385 1.675 10.898 1.00 25.56 C +ATOM 1547 C MET A 115 26.330 2.850 11.186 1.00 25.01 C +ATOM 1548 O MET A 115 27.101 3.210 10.302 1.00 22.73 O +ATOM 1549 CB MET A 115 24.050 2.181 10.296 1.00 28.20 C +ATOM 1550 CG MET A 115 23.882 1.813 8.819 1.00 36.97 C +ATOM 1551 SD MET A 115 23.787 0.024 8.540 1.00 41.03 S +ATOM 1552 CE MET A 115 24.716 -0.077 7.001 1.00 40.29 C +ATOM 1553 H MET A 115 24.161 0.751 12.351 1.00 23.61 H +ATOM 1554 HA MET A 115 25.889 1.049 10.161 1.00 25.56 H +ATOM 1555 HB3 MET A 115 23.960 3.262 10.401 1.00 28.20 H +ATOM 1556 HB2 MET A 115 23.194 1.784 10.837 1.00 28.20 H +ATOM 1557 HG3 MET A 115 24.714 2.230 8.252 1.00 36.97 H +ATOM 1558 HG2 MET A 115 22.978 2.270 8.415 1.00 36.97 H +ATOM 1559 HE1 MET A 115 24.860 -1.119 6.736 1.00 40.29 H +ATOM 1560 HE2 MET A 115 24.180 0.428 6.199 1.00 40.29 H +ATOM 1561 HE3 MET A 115 25.697 0.381 7.124 1.00 40.29 H +ATOM 1562 N GLU A 116 26.241 3.432 12.389 1.00 24.06 N +ATOM 1563 CA GLU A 116 26.899 4.688 12.749 1.00 25.23 C +ATOM 1564 C GLU A 116 27.826 4.525 13.943 1.00 25.96 C +ATOM 1565 O GLU A 116 28.910 5.108 13.950 1.00 25.46 O +ATOM 1566 CB GLU A 116 25.842 5.731 13.139 1.00 25.27 C +ATOM 1567 CG GLU A 116 24.681 5.814 12.145 1.00 28.22 C +ATOM 1568 CD GLU A 116 23.925 7.134 12.194 1.00 28.85 C +ATOM 1569 OE1 GLU A 116 23.921 7.810 13.248 1.00 30.85 O +ATOM 1570 OE2 GLU A 116 23.365 7.458 11.130 1.00 32.46 O1- +ATOM 1571 H GLU A 116 25.565 3.083 13.058 1.00 24.06 H +ATOM 1572 HA GLU A 116 27.482 5.077 11.912 1.00 25.23 H +ATOM 1573 HB3 GLU A 116 26.339 6.696 13.227 1.00 25.27 H +ATOM 1574 HB2 GLU A 116 25.435 5.536 14.133 1.00 25.27 H +ATOM 1575 HG3 GLU A 116 23.969 5.011 12.337 1.00 28.22 H +ATOM 1576 HG2 GLU A 116 25.051 5.652 11.135 1.00 28.22 H +ATOM 1577 N GLY A 117 27.354 3.768 14.944 1.00 24.48 N +ATOM 1578 CA GLY A 117 27.987 3.678 16.245 1.00 25.32 C +ATOM 1579 C GLY A 117 27.735 4.949 17.053 1.00 27.26 C +ATOM 1580 O GLY A 117 26.839 5.745 16.765 1.00 27.39 O +ATOM 1581 H GLY A 117 26.444 3.337 14.849 1.00 24.48 H +ATOM 1582 HA3 GLY A 117 29.054 3.530 16.112 1.00 25.32 H +ATOM 1583 HA2 GLY A 117 27.601 2.831 16.808 1.00 25.32 H +ATOM 1584 N GLU A 118 28.550 5.102 18.096 1.00 28.11 N +ATOM 1585 CA GLU A 118 28.487 6.196 19.053 1.00 28.54 C +ATOM 1586 C GLU A 118 29.873 6.386 19.675 1.00 29.30 C +ATOM 1587 O GLU A 118 30.763 5.558 19.483 1.00 27.87 O +ATOM 1588 CB GLU A 118 27.388 5.893 20.096 1.00 31.14 C +ATOM 1589 CG GLU A 118 27.600 4.600 20.918 1.00 32.60 C +ATOM 1590 CD GLU A 118 26.412 4.280 21.833 1.00 34.85 C +ATOM 1591 OE1 GLU A 118 25.272 4.234 21.316 1.00 33.99 O +ATOM 1592 OE2 GLU A 118 26.658 4.072 23.040 1.00 36.88 O1- +ATOM 1593 H GLU A 118 29.272 4.415 18.270 1.00 28.11 H +ATOM 1594 HA GLU A 118 28.238 7.120 18.528 1.00 28.54 H +ATOM 1595 HB3 GLU A 118 26.429 5.861 19.577 1.00 31.14 H +ATOM 1596 HB2 GLU A 118 27.307 6.731 20.788 1.00 31.14 H +ATOM 1597 HG3 GLU A 118 28.514 4.679 21.509 1.00 32.60 H +ATOM 1598 HG2 GLU A 118 27.741 3.746 20.254 1.00 32.60 H +ATOM 1599 N ARG A 119 30.028 7.492 20.411 1.00 28.64 N +ATOM 1600 CA ARG A 119 31.229 7.764 21.190 1.00 31.10 C +ATOM 1601 C ARG A 119 31.181 7.022 22.530 1.00 30.49 C +ATOM 1602 O ARG A 119 30.154 7.060 23.212 1.00 30.81 O +ATOM 1603 CB ARG A 119 31.395 9.287 21.404 1.00 31.76 C +ATOM 1604 CG ARG A 119 31.425 10.139 20.114 1.00 32.25 C +ATOM 1605 CD ARG A 119 32.334 9.605 18.990 1.00 35.36 C +ATOM 1606 NE ARG A 119 33.708 9.358 19.453 1.00 36.57 N +ATOM 1607 CZ ARG A 119 34.644 10.249 19.821 1.00 34.93 C +ATOM 1608 NH1 ARG A 119 34.510 11.570 19.649 1.00 36.05 N +ATOM 1609 NH2 ARG A 119 35.750 9.786 20.404 1.00 36.63 N1+ +ATOM 1610 H ARG A 119 29.262 8.140 20.519 1.00 28.64 H +ATOM 1611 HA ARG A 119 32.092 7.396 20.634 1.00 31.10 H +ATOM 1612 HB3 ARG A 119 32.321 9.460 21.955 1.00 31.76 H +ATOM 1613 HB2 ARG A 119 30.610 9.670 22.054 1.00 31.76 H +ATOM 1614 HG3 ARG A 119 31.628 11.190 20.323 1.00 32.25 H +ATOM 1615 HG2 ARG A 119 30.407 10.127 19.723 1.00 32.25 H +ATOM 1616 HD3 ARG A 119 32.416 10.358 18.212 1.00 35.36 H +ATOM 1617 HD2 ARG A 119 31.894 8.735 18.510 1.00 35.36 H +ATOM 1618 HE ARG A 119 33.910 8.387 19.662 1.00 36.57 H +ATOM 1619 HH12 ARG A 119 35.227 12.208 19.963 1.00 36.05 H +ATOM 1620 HH11 ARG A 119 33.688 11.937 19.185 1.00 36.05 H +ATOM 1621 HH22 ARG A 119 36.471 10.409 20.742 1.00 36.63 H +ATOM 1622 HH21 ARG A 119 35.849 8.793 20.574 1.00 36.63 H +ATOM 1623 N SER A 120 32.322 6.419 22.899 1.00 32.22 N +ATOM 1624 CA SER A 120 32.587 5.871 24.228 1.00 32.57 C +ATOM 1625 C SER A 120 32.531 7.002 25.279 1.00 32.68 C +ATOM 1626 O SER A 120 33.111 8.060 25.020 1.00 31.36 O +ATOM 1627 CB SER A 120 33.986 5.226 24.243 1.00 32.71 C +ATOM 1628 OG SER A 120 33.976 3.966 23.608 1.00 34.94 O +ATOM 1629 H SER A 120 33.108 6.418 22.259 1.00 32.22 H +ATOM 1630 HA SER A 120 31.849 5.097 24.407 1.00 32.57 H +ATOM 1631 HB3 SER A 120 34.331 5.067 25.266 1.00 32.71 H +ATOM 1632 HB2 SER A 120 34.717 5.867 23.761 1.00 32.71 H +ATOM 1633 HG SER A 120 33.912 4.110 22.657 1.00 34.94 H +ATOM 1634 N PRO A 121 31.827 6.786 26.416 1.00 34.84 N +ATOM 1635 CA PRO A 121 31.739 7.769 27.517 1.00 37.38 C +ATOM 1636 C PRO A 121 33.075 8.361 28.004 1.00 39.81 C +ATOM 1637 O PRO A 121 34.088 7.662 28.018 1.00 39.38 O +ATOM 1638 CB PRO A 121 31.059 6.978 28.647 1.00 38.04 C +ATOM 1639 CG PRO A 121 30.200 5.954 27.933 1.00 38.85 C +ATOM 1640 CD PRO A 121 31.046 5.584 26.725 1.00 35.74 C +ATOM 1641 HA PRO A 121 31.078 8.569 27.179 1.00 37.38 H +ATOM 1642 HB3 PRO A 121 30.475 7.613 29.313 1.00 38.04 H +ATOM 1643 HB2 PRO A 121 31.801 6.457 29.255 1.00 38.04 H +ATOM 1644 HG3 PRO A 121 29.278 6.431 27.598 1.00 38.85 H +ATOM 1645 HG2 PRO A 121 29.932 5.099 28.554 1.00 38.85 H +ATOM 1646 HD2 PRO A 121 31.729 4.767 26.962 1.00 35.74 H +ATOM 1647 HD3 PRO A 121 30.387 5.270 25.915 1.00 35.74 H +ATOM 1648 N ASN A 122 33.023 9.640 28.414 1.00 41.25 N +ATOM 1649 CA ASN A 122 34.096 10.377 29.097 1.00 43.22 C +ATOM 1650 C ASN A 122 35.334 10.693 28.223 1.00 44.35 C +ATOM 1651 O ASN A 122 36.402 10.950 28.778 1.00 44.32 O +ATOM 1652 CB ASN A 122 34.481 9.651 30.421 1.00 42.57 C +ATOM 1653 CG ASN A 122 35.081 10.549 31.509 1.00 44.13 C +ATOM 1654 OD1 ASN A 122 34.754 11.729 31.616 1.00 43.28 O +ATOM 1655 ND2 ASN A 122 35.964 9.982 32.334 1.00 42.61 N +ATOM 1656 H ASN A 122 32.146 10.134 28.344 1.00 41.25 H +ATOM 1657 HA ASN A 122 33.708 11.369 29.330 1.00 43.22 H +ATOM 1658 HB3 ASN A 122 35.141 8.804 30.221 1.00 42.57 H +ATOM 1659 HB2 ASN A 122 33.580 9.230 30.870 1.00 42.57 H +ATOM 1660 HD22 ASN A 122 36.390 10.528 33.068 1.00 42.61 H +ATOM 1661 HD21 ASN A 122 36.221 9.012 32.222 1.00 42.61 H +ATOM 1662 N GLU A 123 35.182 10.689 26.884 1.00 44.87 N +ATOM 1663 CA GLU A 123 36.237 10.983 25.900 1.00 45.91 C +ATOM 1664 C GLU A 123 37.492 10.091 26.054 1.00 45.85 C +ATOM 1665 O GLU A 123 38.608 10.613 26.022 1.00 45.69 O +ATOM 1666 CB GLU A 123 36.618 12.488 25.904 1.00 46.51 C +ATOM 1667 CG GLU A 123 35.465 13.470 25.625 1.00 49.83 C +ATOM 1668 CD GLU A 123 35.978 14.909 25.460 1.00 51.36 C +ATOM 1669 OE1 GLU A 123 36.522 15.450 26.449 1.00 52.20 O +ATOM 1670 OE2 GLU A 123 35.824 15.447 24.341 1.00 52.40 O1- +ATOM 1671 H GLU A 123 34.277 10.463 26.499 1.00 44.87 H +ATOM 1672 HA GLU A 123 35.817 10.750 24.921 1.00 45.91 H +ATOM 1673 HB3 GLU A 123 37.388 12.660 25.149 1.00 46.51 H +ATOM 1674 HB2 GLU A 123 37.082 12.744 26.858 1.00 46.51 H +ATOM 1675 HG3 GLU A 123 34.742 13.446 26.442 1.00 49.83 H +ATOM 1676 HG2 GLU A 123 34.926 13.158 24.729 1.00 49.83 H +ATOM 1677 N GLU A 124 37.301 8.770 26.239 1.00 45.90 N +ATOM 1678 CA GLU A 124 38.400 7.801 26.356 1.00 46.68 C +ATOM 1679 C GLU A 124 39.345 7.778 25.144 1.00 46.72 C +ATOM 1680 O GLU A 124 40.561 7.776 25.328 1.00 46.68 O +ATOM 1681 CB GLU A 124 37.866 6.373 26.591 1.00 48.60 C +ATOM 1682 CG GLU A 124 37.466 6.069 28.046 1.00 51.23 C +ATOM 1683 CD GLU A 124 37.313 4.561 28.298 1.00 52.35 C +ATOM 1684 OE1 GLU A 124 38.315 3.834 28.112 1.00 52.94 O +ATOM 1685 OE2 GLU A 124 36.197 4.153 28.687 1.00 53.19 O1- +ATOM 1686 H GLU A 124 36.364 8.397 26.284 1.00 45.90 H +ATOM 1687 HA GLU A 124 39.004 8.092 27.218 1.00 46.68 H +ATOM 1688 HB3 GLU A 124 38.611 5.649 26.254 1.00 48.60 H +ATOM 1689 HB2 GLU A 124 36.994 6.206 25.958 1.00 48.60 H +ATOM 1690 HG3 GLU A 124 36.548 6.602 28.299 1.00 51.23 H +ATOM 1691 HG2 GLU A 124 38.231 6.442 28.728 1.00 51.23 H +ATOM 1692 N TYR A 125 38.753 7.747 23.944 1.00 44.20 N +ATOM 1693 CA TYR A 125 39.460 7.603 22.678 1.00 43.39 C +ATOM 1694 C TYR A 125 39.227 8.852 21.824 1.00 43.25 C +ATOM 1695 O TYR A 125 38.278 9.603 22.054 1.00 43.62 O +ATOM 1696 CB TYR A 125 38.926 6.355 21.932 1.00 43.13 C +ATOM 1697 CG TYR A 125 38.839 5.088 22.766 1.00 42.67 C +ATOM 1698 CD1 TYR A 125 37.653 4.810 23.472 1.00 41.89 C +ATOM 1699 CD2 TYR A 125 39.932 4.203 22.861 1.00 42.68 C +ATOM 1700 CE1 TYR A 125 37.562 3.675 24.298 1.00 41.87 C +ATOM 1701 CE2 TYR A 125 39.838 3.056 23.677 1.00 40.06 C +ATOM 1702 CZ TYR A 125 38.658 2.799 24.404 1.00 41.85 C +ATOM 1703 OH TYR A 125 38.576 1.706 25.216 1.00 42.69 O +ATOM 1704 H TYR A 125 37.745 7.806 23.885 1.00 44.20 H +ATOM 1705 HA TYR A 125 40.534 7.488 22.833 1.00 43.39 H +ATOM 1706 HB3 TYR A 125 39.537 6.153 21.052 1.00 43.13 H +ATOM 1707 HB2 TYR A 125 37.923 6.559 21.551 1.00 43.13 H +ATOM 1708 HD1 TYR A 125 36.819 5.489 23.400 1.00 41.89 H +ATOM 1709 HD2 TYR A 125 40.845 4.406 22.320 1.00 42.68 H +ATOM 1710 HE1 TYR A 125 36.654 3.487 24.852 1.00 41.87 H +ATOM 1711 HE2 TYR A 125 40.679 2.383 23.755 1.00 40.06 H +ATOM 1712 HH TYR A 125 37.807 1.727 25.790 1.00 42.69 H +ATOM 1713 N THR A 126 40.058 8.987 20.785 1.00 42.92 N +ATOM 1714 CA THR A 126 39.752 9.778 19.596 1.00 43.57 C +ATOM 1715 C THR A 126 38.758 8.984 18.710 1.00 42.84 C +ATOM 1716 O THR A 126 38.630 7.772 18.894 1.00 42.17 O +ATOM 1717 CB THR A 126 41.062 10.065 18.818 1.00 44.90 C +ATOM 1718 OG1 THR A 126 41.562 8.932 18.130 1.00 44.67 O +ATOM 1719 CG2 THR A 126 42.184 10.664 19.681 1.00 45.17 C +ATOM 1720 H THR A 126 40.829 8.343 20.678 1.00 42.92 H +ATOM 1721 HA THR A 126 39.292 10.725 19.888 1.00 43.57 H +ATOM 1722 HB THR A 126 40.825 10.817 18.067 1.00 44.90 H +ATOM 1723 HG1 THR A 126 41.244 8.977 17.222 1.00 44.67 H +ATOM 1724 HG21 THR A 126 43.038 10.945 19.066 1.00 45.17 H +ATOM 1725 HG22 THR A 126 41.843 11.560 20.200 1.00 45.17 H +ATOM 1726 HG23 THR A 126 42.542 9.958 20.431 1.00 45.17 H +ATOM 1727 N TRP A 127 38.039 9.657 17.792 1.00 42.95 N +ATOM 1728 CA TRP A 127 36.971 9.026 16.996 1.00 43.84 C +ATOM 1729 C TRP A 127 37.456 7.869 16.094 1.00 44.40 C +ATOM 1730 O TRP A 127 36.702 6.923 15.878 1.00 42.80 O +ATOM 1731 CB TRP A 127 36.197 10.097 16.200 1.00 42.89 C +ATOM 1732 CG TRP A 127 36.894 10.708 15.021 1.00 42.66 C +ATOM 1733 CD1 TRP A 127 37.614 11.851 15.050 1.00 44.16 C +ATOM 1734 CD2 TRP A 127 37.031 10.178 13.662 1.00 43.10 C +ATOM 1735 NE1 TRP A 127 38.178 12.071 13.812 1.00 43.55 N +ATOM 1736 CE2 TRP A 127 37.867 11.064 12.923 1.00 43.27 C +ATOM 1737 CE3 TRP A 127 36.565 9.027 12.981 1.00 45.46 C +ATOM 1738 CZ2 TRP A 127 38.235 10.813 11.592 1.00 43.09 C +ATOM 1739 CZ3 TRP A 127 36.904 8.778 11.635 1.00 44.80 C +ATOM 1740 CH2 TRP A 127 37.743 9.669 10.939 1.00 45.11 C +ATOM 1741 H TRP A 127 38.188 10.645 17.651 1.00 42.95 H +ATOM 1742 HA TRP A 127 36.268 8.596 17.711 1.00 43.84 H +ATOM 1743 HB3 TRP A 127 35.868 10.893 16.870 1.00 42.89 H +ATOM 1744 HB2 TRP A 127 35.281 9.650 15.819 1.00 42.89 H +ATOM 1745 HD1 TRP A 127 37.737 12.476 15.923 1.00 44.16 H +ATOM 1746 HE1 TRP A 127 38.799 12.846 13.626 1.00 43.55 H +ATOM 1747 HE3 TRP A 127 35.955 8.308 13.504 1.00 45.46 H +ATOM 1748 HZ2 TRP A 127 38.917 11.486 11.102 1.00 43.09 H +ATOM 1749 HZ3 TRP A 127 36.531 7.891 11.144 1.00 44.80 H +ATOM 1750 HH2 TRP A 127 38.019 9.469 9.914 1.00 45.11 H +ATOM 1751 N GLU A 128 38.710 7.954 15.617 1.00 45.51 N +ATOM 1752 CA GLU A 128 39.398 6.942 14.814 1.00 46.17 C +ATOM 1753 C GLU A 128 39.657 5.634 15.581 1.00 44.95 C +ATOM 1754 O GLU A 128 39.607 4.565 14.975 1.00 45.02 O +ATOM 1755 CB GLU A 128 40.754 7.490 14.311 1.00 48.66 C +ATOM 1756 CG GLU A 128 40.691 8.813 13.515 1.00 52.56 C +ATOM 1757 CD GLU A 128 40.914 10.115 14.309 1.00 55.33 C +ATOM 1758 OE1 GLU A 128 41.225 11.131 13.651 1.00 56.74 O +ATOM 1759 OE2 GLU A 128 40.761 10.106 15.547 1.00 55.59 O1- +ATOM 1760 H GLU A 128 39.257 8.784 15.818 1.00 45.51 H +ATOM 1761 HA GLU A 128 38.770 6.715 13.950 1.00 46.17 H +ATOM 1762 HB3 GLU A 128 41.195 6.739 13.655 1.00 48.66 H +ATOM 1763 HB2 GLU A 128 41.461 7.575 15.139 1.00 48.66 H +ATOM 1764 HG3 GLU A 128 39.740 8.874 12.989 1.00 52.56 H +ATOM 1765 HG2 GLU A 128 41.447 8.756 12.734 1.00 52.56 H +ATOM 1766 N GLU A 129 39.943 5.757 16.887 1.00 42.89 N +ATOM 1767 CA GLU A 129 40.312 4.658 17.778 1.00 42.13 C +ATOM 1768 C GLU A 129 39.141 4.139 18.624 1.00 41.35 C +ATOM 1769 O GLU A 129 39.318 3.133 19.310 1.00 39.97 O +ATOM 1770 CB GLU A 129 41.457 5.134 18.691 1.00 46.76 C +ATOM 1771 CG GLU A 129 42.753 5.444 17.913 1.00 51.38 C +ATOM 1772 CD GLU A 129 43.966 5.784 18.793 1.00 54.75 C +ATOM 1773 OE1 GLU A 129 43.773 6.200 19.958 1.00 56.39 O +ATOM 1774 OE2 GLU A 129 45.091 5.619 18.272 1.00 57.50 O1- +ATOM 1775 H GLU A 129 39.949 6.677 17.305 1.00 42.89 H +ATOM 1776 HA GLU A 129 40.674 3.811 17.193 1.00 42.13 H +ATOM 1777 HB3 GLU A 129 41.666 4.380 19.453 1.00 46.76 H +ATOM 1778 HB2 GLU A 129 41.137 6.028 19.228 1.00 46.76 H +ATOM 1779 HG3 GLU A 129 42.591 6.284 17.235 1.00 51.38 H +ATOM 1780 HG2 GLU A 129 43.004 4.588 17.285 1.00 51.38 H +ATOM 1781 N ASP A 130 37.984 4.823 18.578 1.00 38.84 N +ATOM 1782 CA ASP A 130 36.802 4.514 19.376 1.00 36.35 C +ATOM 1783 C ASP A 130 36.222 3.145 18.943 1.00 34.79 C +ATOM 1784 O ASP A 130 35.811 3.019 17.788 1.00 33.59 O +ATOM 1785 CB ASP A 130 35.758 5.649 19.243 1.00 37.00 C +ATOM 1786 CG ASP A 130 34.789 5.722 20.430 1.00 37.96 C +ATOM 1787 OD1 ASP A 130 34.764 6.790 21.075 1.00 37.28 O +ATOM 1788 OD2 ASP A 130 34.098 4.718 20.702 1.00 37.20 O1- +ATOM 1789 H ASP A 130 37.922 5.642 17.989 1.00 38.84 H +ATOM 1790 HA ASP A 130 37.147 4.505 20.408 1.00 36.35 H +ATOM 1791 HB3 ASP A 130 35.182 5.546 18.322 1.00 37.00 H +ATOM 1792 HB2 ASP A 130 36.271 6.606 19.133 1.00 37.00 H +ATOM 1793 N PRO A 131 36.208 2.142 19.855 1.00 34.64 N +ATOM 1794 CA PRO A 131 35.711 0.793 19.533 1.00 33.09 C +ATOM 1795 C PRO A 131 34.185 0.699 19.343 1.00 30.37 C +ATOM 1796 O PRO A 131 33.726 -0.330 18.848 1.00 29.21 O +ATOM 1797 CB PRO A 131 36.193 -0.058 20.716 1.00 34.60 C +ATOM 1798 CG PRO A 131 36.187 0.905 21.890 1.00 35.14 C +ATOM 1799 CD PRO A 131 36.628 2.219 21.257 1.00 34.51 C +ATOM 1800 HA PRO A 131 36.185 0.431 18.620 1.00 33.09 H +ATOM 1801 HB3 PRO A 131 37.212 -0.398 20.526 1.00 34.60 H +ATOM 1802 HB2 PRO A 131 35.583 -0.944 20.902 1.00 34.60 H +ATOM 1803 HG3 PRO A 131 36.825 0.591 22.717 1.00 35.14 H +ATOM 1804 HG2 PRO A 131 35.170 1.008 22.272 1.00 35.14 H +ATOM 1805 HD2 PRO A 131 36.175 3.059 21.783 1.00 34.51 H +ATOM 1806 HD3 PRO A 131 37.712 2.319 21.304 1.00 34.51 H +ATOM 1807 N LEU A 132 33.441 1.758 19.712 1.00 28.68 N +ATOM 1808 CA LEU A 132 31.997 1.874 19.520 1.00 26.61 C +ATOM 1809 C LEU A 132 31.618 2.564 18.198 1.00 26.87 C +ATOM 1810 O LEU A 132 30.422 2.668 17.942 1.00 24.37 O +ATOM 1811 CB LEU A 132 31.344 2.590 20.725 1.00 25.86 C +ATOM 1812 CG LEU A 132 31.572 1.931 22.100 1.00 27.89 C +ATOM 1813 CD1 LEU A 132 30.827 2.718 23.197 1.00 26.82 C +ATOM 1814 CD2 LEU A 132 31.207 0.435 22.132 1.00 27.95 C +ATOM 1815 H LEU A 132 33.891 2.572 20.114 1.00 28.68 H +ATOM 1816 HA LEU A 132 31.566 0.875 19.463 1.00 26.61 H +ATOM 1817 HB3 LEU A 132 30.268 2.660 20.559 1.00 25.86 H +ATOM 1818 HB2 LEU A 132 31.700 3.616 20.775 1.00 25.86 H +ATOM 1819 HG LEU A 132 32.636 2.006 22.323 1.00 27.89 H +ATOM 1820 HD11 LEU A 132 31.444 2.814 24.090 1.00 26.82 H +ATOM 1821 HD12 LEU A 132 30.565 3.725 22.871 1.00 26.82 H +ATOM 1822 HD13 LEU A 132 29.898 2.232 23.493 1.00 26.82 H +ATOM 1823 HD21 LEU A 132 30.730 0.145 23.068 1.00 27.95 H +ATOM 1824 HD22 LEU A 132 30.523 0.168 21.329 1.00 27.95 H +ATOM 1825 HD23 LEU A 132 32.101 -0.180 22.023 1.00 27.95 H +ATOM 1826 N ALA A 133 32.596 2.973 17.363 1.00 25.36 N +ATOM 1827 CA ALA A 133 32.378 3.463 15.994 1.00 25.95 C +ATOM 1828 C ALA A 133 31.762 2.377 15.100 1.00 25.66 C +ATOM 1829 O ALA A 133 32.189 1.231 15.192 1.00 23.39 O +ATOM 1830 CB ALA A 133 33.726 3.923 15.414 1.00 22.78 C +ATOM 1831 H ALA A 133 33.561 2.871 17.646 1.00 25.36 H +ATOM 1832 HA ALA A 133 31.692 4.309 16.039 1.00 25.95 H +ATOM 1833 HB1 ALA A 133 33.595 4.415 14.451 1.00 22.78 H +ATOM 1834 HB2 ALA A 133 34.219 4.632 16.078 1.00 22.78 H +ATOM 1835 HB3 ALA A 133 34.410 3.086 15.268 1.00 22.78 H +ATOM 1836 N GLY A 134 30.772 2.739 14.272 1.00 26.37 N +ATOM 1837 CA GLY A 134 30.015 1.791 13.452 1.00 24.19 C +ATOM 1838 C GLY A 134 30.543 1.771 12.017 1.00 26.33 C +ATOM 1839 O GLY A 134 31.680 2.159 11.749 1.00 25.05 O +ATOM 1840 H GLY A 134 30.473 3.705 14.241 1.00 26.37 H +ATOM 1841 HA3 GLY A 134 28.964 2.069 13.447 1.00 24.19 H +ATOM 1842 HA2 GLY A 134 30.057 0.780 13.858 1.00 24.19 H +ATOM 1843 N ILE A 135 29.699 1.273 11.101 1.00 26.17 N +ATOM 1844 CA ILE A 135 30.011 1.047 9.689 1.00 26.40 C +ATOM 1845 C ILE A 135 30.429 2.323 8.931 1.00 27.39 C +ATOM 1846 O ILE A 135 31.471 2.289 8.285 1.00 28.26 O +ATOM 1847 CB ILE A 135 28.844 0.323 8.946 1.00 27.45 C +ATOM 1848 CG1 ILE A 135 28.660 -1.103 9.526 1.00 25.10 C +ATOM 1849 CG2 ILE A 135 28.981 0.289 7.405 1.00 27.06 C +ATOM 1850 CD1 ILE A 135 27.487 -1.903 8.948 1.00 23.56 C +ATOM 1851 H ILE A 135 28.779 0.972 11.397 1.00 26.17 H +ATOM 1852 HA ILE A 135 30.875 0.378 9.673 1.00 26.40 H +ATOM 1853 HB ILE A 135 27.927 0.871 9.160 1.00 27.45 H +ATOM 1854 HG13 ILE A 135 28.518 -1.050 10.599 1.00 25.10 H +ATOM 1855 HG12 ILE A 135 29.574 -1.677 9.424 1.00 25.10 H +ATOM 1856 HG21 ILE A 135 28.166 -0.257 6.934 1.00 27.06 H +ATOM 1857 HG22 ILE A 135 28.956 1.286 6.967 1.00 27.06 H +ATOM 1858 HG23 ILE A 135 29.913 -0.180 7.099 1.00 27.06 H +ATOM 1859 HD11 ILE A 135 27.298 -2.788 9.554 1.00 23.56 H +ATOM 1860 HD12 ILE A 135 26.573 -1.310 8.931 1.00 23.56 H +ATOM 1861 HD13 ILE A 135 27.690 -2.249 7.934 1.00 23.56 H +ATOM 1862 N ILE A 136 29.640 3.407 9.040 1.00 28.24 N +ATOM 1863 CA ILE A 136 29.866 4.696 8.376 1.00 28.10 C +ATOM 1864 C ILE A 136 31.250 5.328 8.672 1.00 28.82 C +ATOM 1865 O ILE A 136 32.006 5.476 7.714 1.00 28.49 O +ATOM 1866 CB ILE A 136 28.701 5.708 8.631 1.00 28.83 C +ATOM 1867 CG1 ILE A 136 27.423 5.289 7.869 1.00 30.10 C +ATOM 1868 CG2 ILE A 136 29.016 7.183 8.289 1.00 28.01 C +ATOM 1869 CD1 ILE A 136 26.135 5.923 8.408 1.00 29.54 C +ATOM 1870 H ILE A 136 28.792 3.343 9.593 1.00 28.24 H +ATOM 1871 HA ILE A 136 29.860 4.476 7.306 1.00 28.10 H +ATOM 1872 HB ILE A 136 28.461 5.661 9.692 1.00 28.83 H +ATOM 1873 HG13 ILE A 136 27.302 4.206 7.888 1.00 30.10 H +ATOM 1874 HG12 ILE A 136 27.528 5.562 6.821 1.00 30.10 H +ATOM 1875 HG21 ILE A 136 28.143 7.818 8.431 1.00 28.01 H +ATOM 1876 HG22 ILE A 136 29.802 7.596 8.919 1.00 28.01 H +ATOM 1877 HG23 ILE A 136 29.321 7.288 7.248 1.00 28.01 H +ATOM 1878 HD11 ILE A 136 25.308 5.213 8.387 1.00 29.54 H +ATOM 1879 HD12 ILE A 136 26.259 6.255 9.435 1.00 29.54 H +ATOM 1880 HD13 ILE A 136 25.844 6.792 7.820 1.00 29.54 H +ATOM 1881 N PRO A 137 31.603 5.656 9.942 1.00 27.97 N +ATOM 1882 CA PRO A 137 32.911 6.275 10.241 1.00 29.98 C +ATOM 1883 C PRO A 137 34.133 5.409 9.883 1.00 31.46 C +ATOM 1884 O PRO A 137 35.117 5.961 9.390 1.00 32.74 O +ATOM 1885 CB PRO A 137 32.846 6.600 11.740 1.00 30.07 C +ATOM 1886 CG PRO A 137 31.811 5.638 12.296 1.00 28.98 C +ATOM 1887 CD PRO A 137 30.800 5.538 11.161 1.00 26.54 C +ATOM 1888 HA PRO A 137 32.997 7.210 9.682 1.00 29.98 H +ATOM 1889 HB3 PRO A 137 32.496 7.625 11.863 1.00 30.07 H +ATOM 1890 HB2 PRO A 137 33.805 6.521 12.255 1.00 30.07 H +ATOM 1891 HG3 PRO A 137 31.376 5.966 13.240 1.00 28.98 H +ATOM 1892 HG2 PRO A 137 32.272 4.665 12.462 1.00 28.98 H +ATOM 1893 HD2 PRO A 137 30.222 4.619 11.236 1.00 26.54 H +ATOM 1894 HD3 PRO A 137 30.110 6.380 11.208 1.00 26.54 H +ATOM 1895 N ARG A 138 34.026 4.081 10.075 1.00 32.19 N +ATOM 1896 CA ARG A 138 35.033 3.106 9.651 1.00 31.81 C +ATOM 1897 C ARG A 138 35.192 3.034 8.126 1.00 34.98 C +ATOM 1898 O ARG A 138 36.327 2.939 7.670 1.00 35.97 O +ATOM 1899 CB ARG A 138 34.697 1.708 10.196 1.00 31.32 C +ATOM 1900 CG ARG A 138 34.800 1.593 11.720 1.00 28.44 C +ATOM 1901 CD ARG A 138 34.463 0.174 12.202 1.00 28.17 C +ATOM 1902 NE ARG A 138 34.462 0.097 13.668 1.00 28.21 N +ATOM 1903 CZ ARG A 138 35.517 0.038 14.500 1.00 30.29 C +ATOM 1904 NH1 ARG A 138 36.782 -0.044 14.061 1.00 28.82 N +ATOM 1905 NH2 ARG A 138 35.296 0.079 15.817 1.00 28.61 N1+ +ATOM 1906 H ARG A 138 33.182 3.702 10.484 1.00 32.19 H +ATOM 1907 HA ARG A 138 35.996 3.413 10.065 1.00 31.81 H +ATOM 1908 HB3 ARG A 138 35.386 0.980 9.766 1.00 31.32 H +ATOM 1909 HB2 ARG A 138 33.698 1.414 9.869 1.00 31.32 H +ATOM 1910 HG3 ARG A 138 34.194 2.342 12.232 1.00 28.44 H +ATOM 1911 HG2 ARG A 138 35.832 1.823 11.987 1.00 28.44 H +ATOM 1912 HD3 ARG A 138 35.213 -0.527 11.835 1.00 28.17 H +ATOM 1913 HD2 ARG A 138 33.508 -0.163 11.797 1.00 28.17 H +ATOM 1914 HE ARG A 138 33.552 0.234 14.093 1.00 28.21 H +ATOM 1915 HH12 ARG A 138 37.554 -0.059 14.711 1.00 28.82 H +ATOM 1916 HH11 ARG A 138 36.969 -0.061 13.069 1.00 28.82 H +ATOM 1917 HH22 ARG A 138 36.067 0.069 16.468 1.00 28.61 H +ATOM 1918 HH21 ARG A 138 34.354 0.176 16.172 1.00 28.61 H +ATOM 1919 N THR A 139 34.079 3.101 7.371 1.00 35.78 N +ATOM 1920 CA THR A 139 34.073 3.106 5.906 1.00 36.79 C +ATOM 1921 C THR A 139 34.789 4.343 5.345 1.00 37.82 C +ATOM 1922 O THR A 139 35.692 4.162 4.533 1.00 35.78 O +ATOM 1923 CB THR A 139 32.640 3.040 5.305 1.00 37.62 C +ATOM 1924 OG1 THR A 139 32.080 1.775 5.587 1.00 35.78 O +ATOM 1925 CG2 THR A 139 32.523 3.258 3.785 1.00 37.13 C +ATOM 1926 H THR A 139 33.175 3.173 7.821 1.00 35.78 H +ATOM 1927 HA THR A 139 34.623 2.223 5.574 1.00 36.79 H +ATOM 1928 HB THR A 139 32.004 3.777 5.795 1.00 37.62 H +ATOM 1929 HG1 THR A 139 31.906 1.732 6.534 1.00 35.78 H +ATOM 1930 HG21 THR A 139 31.495 3.118 3.457 1.00 37.13 H +ATOM 1931 HG22 THR A 139 32.797 4.272 3.494 1.00 37.13 H +ATOM 1932 HG23 THR A 139 33.152 2.561 3.232 1.00 37.13 H +ATOM 1933 N LEU A 140 34.419 5.551 5.813 1.00 39.09 N +ATOM 1934 CA LEU A 140 35.057 6.808 5.409 1.00 40.74 C +ATOM 1935 C LEU A 140 36.559 6.833 5.729 1.00 42.29 C +ATOM 1936 O LEU A 140 37.342 7.149 4.836 1.00 42.16 O +ATOM 1937 CB LEU A 140 34.361 8.037 6.044 1.00 40.56 C +ATOM 1938 CG LEU A 140 33.082 8.569 5.359 1.00 42.13 C +ATOM 1939 CD1 LEU A 140 33.229 8.796 3.845 1.00 41.68 C +ATOM 1940 CD2 LEU A 140 31.831 7.757 5.698 1.00 45.74 C +ATOM 1941 H LEU A 140 33.673 5.622 6.493 1.00 39.09 H +ATOM 1942 HA LEU A 140 34.978 6.865 4.325 1.00 40.74 H +ATOM 1943 HB3 LEU A 140 35.068 8.864 6.014 1.00 40.56 H +ATOM 1944 HB2 LEU A 140 34.175 7.859 7.104 1.00 40.56 H +ATOM 1945 HG LEU A 140 32.912 9.556 5.794 1.00 42.13 H +ATOM 1946 HD11 LEU A 140 32.799 9.753 3.551 1.00 41.68 H +ATOM 1947 HD12 LEU A 140 34.270 8.814 3.524 1.00 41.68 H +ATOM 1948 HD13 LEU A 140 32.718 8.017 3.282 1.00 41.68 H +ATOM 1949 HD21 LEU A 140 30.960 8.173 5.198 1.00 45.74 H +ATOM 1950 HD22 LEU A 140 31.923 6.716 5.390 1.00 45.74 H +ATOM 1951 HD23 LEU A 140 31.633 7.798 6.767 1.00 45.74 H +ATOM 1952 N HIS A 141 36.933 6.455 6.965 1.00 42.88 N +ATOM 1953 CA HIS A 141 38.323 6.362 7.417 1.00 44.87 C +ATOM 1954 C HIS A 141 39.172 5.410 6.556 1.00 44.22 C +ATOM 1955 O HIS A 141 40.252 5.805 6.121 1.00 43.81 O +ATOM 1956 CB HIS A 141 38.364 5.966 8.907 1.00 46.81 C +ATOM 1957 CG HIS A 141 39.755 5.914 9.494 1.00 50.62 C +ATOM 1958 ND1 HIS A 141 40.556 4.783 9.456 1.00 52.14 N +ATOM 1959 CD2 HIS A 141 40.506 6.879 10.125 1.00 51.05 C +ATOM 1960 CE1 HIS A 141 41.724 5.111 10.016 1.00 52.04 C +ATOM 1961 NE2 HIS A 141 41.765 6.367 10.446 1.00 50.72 N +ATOM 1962 H HIS A 141 36.226 6.201 7.644 1.00 42.88 H +ATOM 1963 HA HIS A 141 38.755 7.360 7.325 1.00 44.87 H +ATOM 1964 HB3 HIS A 141 37.884 4.998 9.058 1.00 46.81 H +ATOM 1965 HB2 HIS A 141 37.789 6.684 9.490 1.00 46.81 H +ATOM 1966 HD1 HIS A 141 40.324 3.889 9.047 1.00 52.14 H +ATOM 1967 HD2 HIS A 141 40.244 7.900 10.357 1.00 51.05 H +ATOM 1968 HE1 HIS A 141 42.555 4.426 10.104 1.00 52.04 H +ATOM 1969 N GLN A 142 38.652 4.194 6.318 1.00 43.78 N +ATOM 1970 CA GLN A 142 39.307 3.161 5.521 1.00 44.19 C +ATOM 1971 C GLN A 142 39.404 3.486 4.024 1.00 44.75 C +ATOM 1972 O GLN A 142 40.373 3.054 3.409 1.00 45.21 O +ATOM 1973 CB GLN A 142 38.637 1.795 5.758 1.00 45.44 C +ATOM 1974 CG GLN A 142 38.894 1.197 7.158 1.00 48.56 C +ATOM 1975 CD GLN A 142 40.296 0.608 7.316 1.00 50.10 C +ATOM 1976 OE1 GLN A 142 41.260 1.338 7.532 1.00 49.63 O +ATOM 1977 NE2 GLN A 142 40.413 -0.718 7.226 1.00 51.81 N +ATOM 1978 H GLN A 142 37.752 3.947 6.709 1.00 43.78 H +ATOM 1979 HA GLN A 142 40.332 3.100 5.881 1.00 44.19 H +ATOM 1980 HB3 GLN A 142 38.957 1.074 5.003 1.00 45.44 H +ATOM 1981 HB2 GLN A 142 37.565 1.911 5.604 1.00 45.44 H +ATOM 1982 HG3 GLN A 142 38.165 0.419 7.366 1.00 48.56 H +ATOM 1983 HG2 GLN A 142 38.747 1.951 7.932 1.00 48.56 H +ATOM 1984 HE22 GLN A 142 41.319 -1.150 7.330 1.00 51.81 H +ATOM 1985 HE21 GLN A 142 39.604 -1.294 7.044 1.00 51.81 H +ATOM 1986 N ILE A 143 38.466 4.278 3.470 1.00 43.60 N +ATOM 1987 CA ILE A 143 38.564 4.817 2.108 1.00 43.61 C +ATOM 1988 C ILE A 143 39.809 5.711 1.944 1.00 45.62 C +ATOM 1989 O ILE A 143 40.591 5.468 1.028 1.00 44.70 O +ATOM 1990 CB ILE A 143 37.278 5.581 1.658 1.00 42.40 C +ATOM 1991 CG1 ILE A 143 36.127 4.588 1.384 1.00 40.31 C +ATOM 1992 CG2 ILE A 143 37.458 6.515 0.436 1.00 40.71 C +ATOM 1993 CD1 ILE A 143 34.728 5.228 1.419 1.00 38.90 C +ATOM 1994 H ILE A 143 37.676 4.585 4.022 1.00 43.60 H +ATOM 1995 HA ILE A 143 38.693 3.965 1.437 1.00 43.61 H +ATOM 1996 HB ILE A 143 36.963 6.210 2.489 1.00 42.40 H +ATOM 1997 HG13 ILE A 143 36.150 3.777 2.110 1.00 40.31 H +ATOM 1998 HG12 ILE A 143 36.285 4.097 0.424 1.00 40.31 H +ATOM 1999 HG21 ILE A 143 36.514 6.960 0.128 1.00 40.71 H +ATOM 2000 HG22 ILE A 143 38.128 7.350 0.646 1.00 40.71 H +ATOM 2001 HG23 ILE A 143 37.857 5.972 -0.421 1.00 40.71 H +ATOM 2002 HD11 ILE A 143 33.951 4.471 1.317 1.00 38.90 H +ATOM 2003 HD12 ILE A 143 34.555 5.750 2.359 1.00 38.90 H +ATOM 2004 HD13 ILE A 143 34.584 5.944 0.612 1.00 38.90 H +ATOM 2005 N PHE A 144 40.008 6.663 2.874 1.00 46.96 N +ATOM 2006 CA PHE A 144 41.208 7.504 2.934 1.00 49.07 C +ATOM 2007 C PHE A 144 42.489 6.763 3.345 1.00 50.61 C +ATOM 2008 O PHE A 144 43.560 7.331 3.162 1.00 51.54 O +ATOM 2009 CB PHE A 144 40.983 8.717 3.858 1.00 48.69 C +ATOM 2010 CG PHE A 144 39.969 9.712 3.337 1.00 49.25 C +ATOM 2011 CD1 PHE A 144 40.245 10.472 2.182 1.00 49.30 C +ATOM 2012 CD2 PHE A 144 38.703 9.816 3.944 1.00 48.10 C +ATOM 2013 CE1 PHE A 144 39.263 11.287 1.639 1.00 48.65 C +ATOM 2014 CE2 PHE A 144 37.731 10.627 3.383 1.00 49.28 C +ATOM 2015 CZ PHE A 144 38.011 11.351 2.233 1.00 49.42 C +ATOM 2016 H PHE A 144 39.328 6.796 3.610 1.00 46.96 H +ATOM 2017 HA PHE A 144 41.395 7.879 1.926 1.00 49.07 H +ATOM 2018 HB3 PHE A 144 41.917 9.259 4.012 1.00 48.69 H +ATOM 2019 HB2 PHE A 144 40.673 8.365 4.841 1.00 48.69 H +ATOM 2020 HD1 PHE A 144 41.215 10.416 1.714 1.00 49.30 H +ATOM 2021 HD2 PHE A 144 38.487 9.269 4.847 1.00 48.10 H +ATOM 2022 HE1 PHE A 144 39.468 11.865 0.749 1.00 48.65 H +ATOM 2023 HE2 PHE A 144 36.755 10.688 3.840 1.00 49.28 H +ATOM 2024 HZ PHE A 144 37.248 11.968 1.796 1.00 49.42 H +ATOM 2025 N GLU A 145 42.386 5.537 3.881 1.00 51.76 N +ATOM 2026 CA GLU A 145 43.545 4.720 4.230 1.00 53.26 C +ATOM 2027 C GLU A 145 44.002 3.875 3.030 1.00 53.56 C +ATOM 2028 O GLU A 145 45.191 3.859 2.727 1.00 53.41 O +ATOM 2029 CB GLU A 145 43.215 3.852 5.466 1.00 54.78 C +ATOM 2030 CG GLU A 145 44.400 3.059 6.056 1.00 58.42 C +ATOM 2031 CD GLU A 145 45.499 3.967 6.626 1.00 60.55 C +ATOM 2032 OE1 GLU A 145 46.488 4.204 5.899 1.00 61.57 O +ATOM 2033 OE2 GLU A 145 45.330 4.414 7.783 1.00 60.12 O1- +ATOM 2034 H GLU A 145 41.475 5.128 4.038 1.00 51.76 H +ATOM 2035 HA GLU A 145 44.368 5.384 4.500 1.00 53.26 H +ATOM 2036 HB3 GLU A 145 42.444 3.132 5.197 1.00 54.78 H +ATOM 2037 HB2 GLU A 145 42.774 4.476 6.246 1.00 54.78 H +ATOM 2038 HG3 GLU A 145 44.823 2.387 5.308 1.00 58.42 H +ATOM 2039 HG2 GLU A 145 44.033 2.412 6.854 1.00 58.42 H +ATOM 2040 N LYS A 146 43.050 3.195 2.371 1.00 52.91 N +ATOM 2041 CA LYS A 146 43.314 2.210 1.323 1.00 53.75 C +ATOM 2042 C LYS A 146 43.578 2.834 -0.060 1.00 54.11 C +ATOM 2043 O LYS A 146 44.247 2.187 -0.861 1.00 53.73 O +ATOM 2044 CB LYS A 146 42.151 1.191 1.273 1.00 54.00 C +ATOM 2045 CG LYS A 146 41.928 0.435 2.607 1.00 56.01 C +ATOM 2046 CD LYS A 146 42.075 -1.090 2.530 1.00 56.78 C +ATOM 2047 CE LYS A 146 40.922 -1.777 1.782 1.00 56.67 C +ATOM 2048 NZ LYS A 146 41.048 -3.243 1.840 1.00 56.24 N1+ +ATOM 2049 H LYS A 146 42.087 3.267 2.676 1.00 52.91 H +ATOM 2050 HA LYS A 146 44.217 1.659 1.597 1.00 53.75 H +ATOM 2051 HB3 LYS A 146 42.335 0.476 0.470 1.00 54.00 H +ATOM 2052 HB2 LYS A 146 41.227 1.705 0.999 1.00 54.00 H +ATOM 2053 HG3 LYS A 146 40.933 0.655 2.988 1.00 56.01 H +ATOM 2054 HG2 LYS A 146 42.617 0.799 3.370 1.00 56.01 H +ATOM 2055 HD3 LYS A 146 42.144 -1.481 3.547 1.00 56.78 H +ATOM 2056 HD2 LYS A 146 43.025 -1.332 2.050 1.00 56.78 H +ATOM 2057 HE3 LYS A 146 40.897 -1.466 0.737 1.00 56.67 H +ATOM 2058 HE2 LYS A 146 39.963 -1.500 2.222 1.00 56.67 H +ATOM 2059 HZ1 LYS A 146 40.276 -3.650 1.322 1.00 56.24 H +ATOM 2060 HZ2 LYS A 146 41.918 -3.530 1.417 1.00 56.24 H +ATOM 2061 HZ3 LYS A 146 41.011 -3.557 2.799 1.00 56.24 H +ATOM 2062 N LEU A 147 43.076 4.056 -0.325 1.00 53.89 N +ATOM 2063 CA LEU A 147 43.275 4.755 -1.603 1.00 54.30 C +ATOM 2064 C LEU A 147 44.414 5.781 -1.547 1.00 56.38 C +ATOM 2065 O LEU A 147 45.034 5.990 -2.588 1.00 57.15 O +ATOM 2066 CB LEU A 147 41.971 5.437 -2.073 1.00 52.68 C +ATOM 2067 CG LEU A 147 41.046 4.548 -2.925 1.00 51.66 C +ATOM 2068 CD1 LEU A 147 40.693 3.211 -2.254 1.00 49.87 C +ATOM 2069 CD2 LEU A 147 39.783 5.332 -3.314 1.00 48.79 C +ATOM 2070 H LEU A 147 42.510 4.528 0.368 1.00 53.89 H +ATOM 2071 HA LEU A 147 43.561 4.039 -2.376 1.00 54.30 H +ATOM 2072 HB3 LEU A 147 42.221 6.286 -2.709 1.00 52.68 H +ATOM 2073 HB2 LEU A 147 41.439 5.869 -1.230 1.00 52.68 H +ATOM 2074 HG LEU A 147 41.570 4.305 -3.852 1.00 51.66 H +ATOM 2075 HD11 LEU A 147 39.750 2.815 -2.616 1.00 49.87 H +ATOM 2076 HD12 LEU A 147 41.453 2.456 -2.460 1.00 49.87 H +ATOM 2077 HD13 LEU A 147 40.603 3.313 -1.172 1.00 49.87 H +ATOM 2078 HD21 LEU A 147 38.968 4.674 -3.612 1.00 48.79 H +ATOM 2079 HD22 LEU A 147 39.422 5.954 -2.494 1.00 48.79 H +ATOM 2080 HD23 LEU A 147 39.994 5.992 -4.153 1.00 48.79 H +ATOM 2081 N THR A 148 44.691 6.386 -0.376 1.00 57.67 N +ATOM 2082 CA THR A 148 45.844 7.284 -0.198 1.00 58.54 C +ATOM 2083 C THR A 148 47.175 6.508 -0.107 1.00 60.02 C +ATOM 2084 O THR A 148 48.210 7.060 -0.480 1.00 59.77 O +ATOM 2085 CB THR A 148 45.720 8.185 1.059 1.00 58.20 C +ATOM 2086 OG1 THR A 148 44.516 8.922 0.985 1.00 58.85 O +ATOM 2087 CG2 THR A 148 46.851 9.207 1.278 1.00 58.05 C +ATOM 2088 H THR A 148 44.149 6.173 0.448 1.00 57.67 H +ATOM 2089 HA THR A 148 45.907 7.938 -1.072 1.00 58.54 H +ATOM 2090 HB THR A 148 45.682 7.548 1.941 1.00 58.20 H +ATOM 2091 HG1 THR A 148 43.790 8.324 1.177 1.00 58.85 H +ATOM 2092 HG21 THR A 148 46.613 9.880 2.103 1.00 58.05 H +ATOM 2093 HG22 THR A 148 47.795 8.724 1.531 1.00 58.05 H +ATOM 2094 HG23 THR A 148 47.012 9.816 0.388 1.00 58.05 H +ATOM 2095 N ASP A 149 47.112 5.233 0.325 1.00 61.81 N +ATOM 2096 CA ASP A 149 48.198 4.247 0.267 1.00 63.39 C +ATOM 2097 C ASP A 149 48.673 4.050 -1.186 1.00 64.18 C +ATOM 2098 O ASP A 149 49.865 4.188 -1.460 1.00 64.37 O +ATOM 2099 CB ASP A 149 47.769 2.947 1.010 1.00 64.12 C +ATOM 2100 CG ASP A 149 48.717 1.730 1.096 1.00 65.61 C +ATOM 2101 OD1 ASP A 149 49.522 1.479 0.172 1.00 66.85 O +ATOM 2102 OD2 ASP A 149 48.519 0.960 2.061 1.00 67.42 O1- +ATOM 2103 H ASP A 149 46.223 4.871 0.640 1.00 61.81 H +ATOM 2104 HA ASP A 149 49.037 4.671 0.822 1.00 63.39 H +ATOM 2105 HB3 ASP A 149 46.823 2.598 0.592 1.00 64.12 H +ATOM 2106 HB2 ASP A 149 47.534 3.237 2.034 1.00 64.12 H +ATOM 2107 N ASN A 150 47.713 3.798 -2.088 1.00 64.99 N +ATOM 2108 CA ASN A 150 47.926 3.705 -3.532 1.00 65.74 C +ATOM 2109 C ASN A 150 48.150 5.098 -4.151 1.00 65.03 C +ATOM 2110 O ASN A 150 47.802 6.117 -3.553 1.00 65.91 O +ATOM 2111 CB ASN A 150 46.702 3.004 -4.171 1.00 67.17 C +ATOM 2112 CG ASN A 150 46.561 1.530 -3.764 1.00 68.38 C +ATOM 2113 OD1 ASN A 150 46.375 1.213 -2.592 1.00 69.69 O +ATOM 2114 ND2 ASN A 150 46.630 0.615 -4.732 1.00 69.67 N +ATOM 2115 H ASN A 150 46.759 3.697 -1.773 1.00 64.99 H +ATOM 2116 HA ASN A 150 48.813 3.088 -3.689 1.00 65.74 H +ATOM 2117 HB3 ASN A 150 46.770 3.053 -5.259 1.00 67.17 H +ATOM 2118 HB2 ASN A 150 45.784 3.528 -3.899 1.00 67.17 H +ATOM 2119 HD22 ASN A 150 46.538 -0.364 -4.502 1.00 69.67 H +ATOM 2120 HD21 ASN A 150 46.765 0.888 -5.694 1.00 69.67 H +ATOM 2121 N GLY A 151 48.679 5.108 -5.385 1.00 64.36 N +ATOM 2122 CA GLY A 151 48.858 6.310 -6.205 1.00 63.41 C +ATOM 2123 C GLY A 151 47.542 6.803 -6.838 1.00 62.81 C +ATOM 2124 O GLY A 151 47.594 7.619 -7.756 1.00 63.61 O +ATOM 2125 H GLY A 151 48.945 4.231 -5.810 1.00 64.36 H +ATOM 2126 HA3 GLY A 151 49.567 6.082 -7.001 1.00 63.41 H +ATOM 2127 HA2 GLY A 151 49.297 7.114 -5.611 1.00 63.41 H +ATOM 2128 N THR A 152 46.379 6.304 -6.380 1.00 60.95 N +ATOM 2129 CA THR A 152 45.049 6.654 -6.871 1.00 59.02 C +ATOM 2130 C THR A 152 44.722 8.134 -6.610 1.00 58.13 C +ATOM 2131 O THR A 152 44.837 8.591 -5.473 1.00 57.82 O +ATOM 2132 CB THR A 152 43.938 5.798 -6.196 1.00 59.09 C +ATOM 2133 OG1 THR A 152 44.261 4.424 -6.291 1.00 59.39 O +ATOM 2134 CG2 THR A 152 42.539 5.969 -6.819 1.00 57.71 C +ATOM 2135 H THR A 152 46.406 5.680 -5.588 1.00 60.95 H +ATOM 2136 HA THR A 152 45.039 6.473 -7.946 1.00 59.02 H +ATOM 2137 HB THR A 152 43.879 6.041 -5.134 1.00 59.09 H +ATOM 2138 HG1 THR A 152 45.064 4.263 -5.791 1.00 59.39 H +ATOM 2139 HG21 THR A 152 41.792 5.397 -6.269 1.00 57.71 H +ATOM 2140 HG22 THR A 152 42.214 7.007 -6.821 1.00 57.71 H +ATOM 2141 HG23 THR A 152 42.521 5.627 -7.854 1.00 57.71 H +ATOM 2142 N GLU A 153 44.316 8.840 -7.674 1.00 56.97 N +ATOM 2143 CA GLU A 153 43.813 10.207 -7.618 1.00 56.69 C +ATOM 2144 C GLU A 153 42.294 10.144 -7.433 1.00 55.11 C +ATOM 2145 O GLU A 153 41.599 9.811 -8.389 1.00 55.09 O +ATOM 2146 CB GLU A 153 44.273 10.944 -8.896 1.00 57.96 C +ATOM 2147 CG GLU A 153 43.615 12.319 -9.151 1.00 60.39 C +ATOM 2148 CD GLU A 153 44.224 13.071 -10.343 1.00 61.93 C +ATOM 2149 OE1 GLU A 153 45.468 13.196 -10.383 1.00 62.34 O +ATOM 2150 OE2 GLU A 153 43.432 13.531 -11.195 1.00 61.46 O1- +ATOM 2151 H GLU A 153 44.278 8.398 -8.583 1.00 56.97 H +ATOM 2152 HA GLU A 153 44.244 10.734 -6.764 1.00 56.69 H +ATOM 2153 HB3 GLU A 153 44.125 10.311 -9.770 1.00 57.96 H +ATOM 2154 HB2 GLU A 153 45.354 11.070 -8.816 1.00 57.96 H +ATOM 2155 HG3 GLU A 153 43.725 12.947 -8.266 1.00 60.39 H +ATOM 2156 HG2 GLU A 153 42.542 12.200 -9.310 1.00 60.39 H +ATOM 2157 N PHE A 154 41.811 10.402 -6.207 1.00 52.70 N +ATOM 2158 CA PHE A 154 40.409 10.189 -5.850 1.00 49.80 C +ATOM 2159 C PHE A 154 39.805 11.395 -5.124 1.00 49.14 C +ATOM 2160 O PHE A 154 40.516 12.198 -4.520 1.00 48.93 O +ATOM 2161 CB PHE A 154 40.270 8.882 -5.029 1.00 48.80 C +ATOM 2162 CG PHE A 154 40.753 8.928 -3.589 1.00 49.66 C +ATOM 2163 CD1 PHE A 154 39.834 9.060 -2.527 1.00 48.25 C +ATOM 2164 CD2 PHE A 154 42.134 8.956 -3.307 1.00 48.95 C +ATOM 2165 CE1 PHE A 154 40.296 9.160 -1.222 1.00 49.33 C +ATOM 2166 CE2 PHE A 154 42.577 9.068 -1.999 1.00 50.09 C +ATOM 2167 CZ PHE A 154 41.661 9.160 -0.961 1.00 50.47 C +ATOM 2168 H PHE A 154 42.428 10.684 -5.459 1.00 52.70 H +ATOM 2169 HA PHE A 154 39.842 10.079 -6.770 1.00 49.80 H +ATOM 2170 HB3 PHE A 154 40.788 8.074 -5.539 1.00 48.80 H +ATOM 2171 HB2 PHE A 154 39.223 8.577 -5.016 1.00 48.80 H +ATOM 2172 HD1 PHE A 154 38.772 9.071 -2.725 1.00 48.25 H +ATOM 2173 HD2 PHE A 154 42.849 8.884 -4.108 1.00 48.95 H +ATOM 2174 HE1 PHE A 154 39.591 9.236 -0.407 1.00 49.33 H +ATOM 2175 HE2 PHE A 154 43.637 9.076 -1.788 1.00 50.09 H +ATOM 2176 HZ PHE A 154 42.016 9.234 0.053 1.00 50.47 H +ATOM 2177 N SER A 155 38.469 11.445 -5.189 1.00 45.90 N +ATOM 2178 CA SER A 155 37.605 12.383 -4.490 1.00 45.47 C +ATOM 2179 C SER A 155 36.435 11.587 -3.901 1.00 43.55 C +ATOM 2180 O SER A 155 35.952 10.651 -4.539 1.00 43.15 O +ATOM 2181 CB SER A 155 37.138 13.465 -5.485 1.00 43.93 C +ATOM 2182 OG SER A 155 36.300 14.422 -4.866 1.00 46.92 O +ATOM 2183 H SER A 155 37.983 10.724 -5.708 1.00 45.90 H +ATOM 2184 HA SER A 155 38.153 12.855 -3.672 1.00 45.47 H +ATOM 2185 HB3 SER A 155 36.597 13.016 -6.319 1.00 43.93 H +ATOM 2186 HB2 SER A 155 37.999 13.985 -5.908 1.00 43.93 H +ATOM 2187 HG SER A 155 36.085 15.101 -5.511 1.00 46.92 H +ATOM 2188 N VAL A 156 36.000 11.984 -2.698 1.00 42.99 N +ATOM 2189 CA VAL A 156 34.894 11.360 -1.981 1.00 40.85 C +ATOM 2190 C VAL A 156 33.810 12.424 -1.770 1.00 40.89 C +ATOM 2191 O VAL A 156 34.131 13.524 -1.330 1.00 42.32 O +ATOM 2192 CB VAL A 156 35.356 10.843 -0.588 1.00 40.60 C +ATOM 2193 CG1 VAL A 156 34.222 10.235 0.260 1.00 41.68 C +ATOM 2194 CG2 VAL A 156 36.494 9.818 -0.715 1.00 41.72 C +ATOM 2195 H VAL A 156 36.427 12.779 -2.245 1.00 42.99 H +ATOM 2196 HA VAL A 156 34.477 10.525 -2.544 1.00 40.85 H +ATOM 2197 HB VAL A 156 35.761 11.686 -0.030 1.00 40.60 H +ATOM 2198 HG11 VAL A 156 34.606 9.830 1.197 1.00 41.68 H +ATOM 2199 HG12 VAL A 156 33.457 10.965 0.524 1.00 41.68 H +ATOM 2200 HG13 VAL A 156 33.741 9.420 -0.281 1.00 41.68 H +ATOM 2201 HG21 VAL A 156 36.798 9.446 0.263 1.00 41.72 H +ATOM 2202 HG22 VAL A 156 36.191 8.963 -1.320 1.00 41.72 H +ATOM 2203 HG23 VAL A 156 37.379 10.259 -1.174 1.00 41.72 H +ATOM 2204 N LYS A 157 32.554 12.066 -2.066 1.00 39.19 N +ATOM 2205 CA LYS A 157 31.364 12.855 -1.753 1.00 37.21 C +ATOM 2206 C LYS A 157 30.448 12.020 -0.860 1.00 35.33 C +ATOM 2207 O LYS A 157 30.394 10.804 -1.033 1.00 33.52 O +ATOM 2208 CB LYS A 157 30.613 13.221 -3.044 1.00 38.54 C +ATOM 2209 CG LYS A 157 31.374 14.195 -3.957 1.00 42.32 C +ATOM 2210 CD LYS A 157 30.564 14.651 -5.183 1.00 44.23 C +ATOM 2211 CE LYS A 157 30.042 13.484 -6.041 1.00 46.31 C +ATOM 2212 NZ LYS A 157 29.441 13.952 -7.301 1.00 48.40 N1+ +ATOM 2213 H LYS A 157 32.378 11.139 -2.432 1.00 39.19 H +ATOM 2214 HA LYS A 157 31.636 13.767 -1.224 1.00 37.21 H +ATOM 2215 HB3 LYS A 157 29.661 13.684 -2.780 1.00 38.54 H +ATOM 2216 HB2 LYS A 157 30.368 12.305 -3.585 1.00 38.54 H +ATOM 2217 HG3 LYS A 157 32.302 13.731 -4.294 1.00 42.32 H +ATOM 2218 HG2 LYS A 157 31.669 15.073 -3.380 1.00 42.32 H +ATOM 2219 HD3 LYS A 157 31.199 15.299 -5.788 1.00 44.23 H +ATOM 2220 HD2 LYS A 157 29.731 15.273 -4.854 1.00 44.23 H +ATOM 2221 HE3 LYS A 157 29.285 12.913 -5.502 1.00 46.31 H +ATOM 2222 HE2 LYS A 157 30.858 12.801 -6.269 1.00 46.31 H +ATOM 2223 HZ1 LYS A 157 28.645 14.539 -7.074 1.00 48.40 H +ATOM 2224 HZ2 LYS A 157 30.113 14.485 -7.834 1.00 48.40 H +ATOM 2225 HZ3 LYS A 157 29.111 13.167 -7.844 1.00 48.40 H +ATOM 2226 N VAL A 158 29.719 12.691 0.042 1.00 34.70 N +ATOM 2227 CA VAL A 158 28.712 12.071 0.897 1.00 32.77 C +ATOM 2228 C VAL A 158 27.419 12.897 0.905 1.00 33.04 C +ATOM 2229 O VAL A 158 27.466 14.124 0.841 1.00 33.91 O +ATOM 2230 CB VAL A 158 29.195 11.895 2.364 1.00 32.67 C +ATOM 2231 CG1 VAL A 158 30.320 10.856 2.474 1.00 31.61 C +ATOM 2232 CG2 VAL A 158 29.590 13.197 3.086 1.00 33.84 C +ATOM 2233 H VAL A 158 29.828 13.693 0.139 1.00 34.70 H +ATOM 2234 HA VAL A 158 28.463 11.094 0.490 1.00 32.77 H +ATOM 2235 HB VAL A 158 28.360 11.477 2.929 1.00 32.67 H +ATOM 2236 HG11 VAL A 158 30.587 10.678 3.516 1.00 31.61 H +ATOM 2237 HG12 VAL A 158 30.008 9.902 2.052 1.00 31.61 H +ATOM 2238 HG13 VAL A 158 31.220 11.177 1.950 1.00 31.61 H +ATOM 2239 HG21 VAL A 158 29.920 12.976 4.100 1.00 33.84 H +ATOM 2240 HG22 VAL A 158 30.411 13.704 2.579 1.00 33.84 H +ATOM 2241 HG23 VAL A 158 28.763 13.901 3.163 1.00 33.84 H +ATOM 2242 N SER A 159 26.288 12.188 1.014 1.00 31.10 N +ATOM 2243 CA SER A 159 24.956 12.763 1.155 1.00 29.81 C +ATOM 2244 C SER A 159 24.130 11.910 2.125 1.00 27.90 C +ATOM 2245 O SER A 159 24.349 10.703 2.221 1.00 26.67 O +ATOM 2246 CB SER A 159 24.300 12.933 -0.234 1.00 29.49 C +ATOM 2247 OG SER A 159 23.938 11.706 -0.832 1.00 33.07 O +ATOM 2248 H SER A 159 26.335 11.178 1.066 1.00 31.10 H +ATOM 2249 HA SER A 159 25.060 13.752 1.604 1.00 29.81 H +ATOM 2250 HB3 SER A 159 24.963 13.476 -0.908 1.00 29.49 H +ATOM 2251 HB2 SER A 159 23.394 13.532 -0.143 1.00 29.49 H +ATOM 2252 HG SER A 159 23.162 11.357 -0.379 1.00 33.07 H +ATOM 2253 N LEU A 160 23.191 12.566 2.816 1.00 28.07 N +ATOM 2254 CA LEU A 160 22.306 11.969 3.803 1.00 24.85 C +ATOM 2255 C LEU A 160 20.880 12.425 3.496 1.00 24.84 C +ATOM 2256 O LEU A 160 20.458 13.495 3.937 1.00 25.97 O +ATOM 2257 CB LEU A 160 22.785 12.377 5.208 1.00 25.10 C +ATOM 2258 CG LEU A 160 22.040 11.742 6.395 1.00 24.01 C +ATOM 2259 CD1 LEU A 160 22.077 10.203 6.383 1.00 23.66 C +ATOM 2260 CD2 LEU A 160 22.594 12.318 7.710 1.00 27.15 C +ATOM 2261 H LEU A 160 23.064 13.561 2.656 1.00 28.07 H +ATOM 2262 HA LEU A 160 22.339 10.883 3.723 1.00 24.85 H +ATOM 2263 HB3 LEU A 160 22.694 13.460 5.286 1.00 25.10 H +ATOM 2264 HB2 LEU A 160 23.844 12.138 5.308 1.00 25.10 H +ATOM 2265 HG LEU A 160 20.996 12.036 6.322 1.00 24.01 H +ATOM 2266 HD11 LEU A 160 22.331 9.789 7.359 1.00 23.66 H +ATOM 2267 HD12 LEU A 160 21.107 9.795 6.098 1.00 23.66 H +ATOM 2268 HD13 LEU A 160 22.809 9.823 5.676 1.00 23.66 H +ATOM 2269 HD21 LEU A 160 21.872 12.248 8.522 1.00 27.15 H +ATOM 2270 HD22 LEU A 160 23.491 11.786 8.013 1.00 27.15 H +ATOM 2271 HD23 LEU A 160 22.870 13.368 7.611 1.00 27.15 H +ATOM 2272 N LEU A 161 20.178 11.585 2.725 1.00 23.65 N +ATOM 2273 CA LEU A 161 18.763 11.735 2.419 1.00 23.59 C +ATOM 2274 C LEU A 161 17.957 10.936 3.440 1.00 21.28 C +ATOM 2275 O LEU A 161 18.292 9.777 3.681 1.00 20.76 O +ATOM 2276 CB LEU A 161 18.505 11.202 0.998 1.00 25.98 C +ATOM 2277 CG LEU A 161 17.033 11.282 0.536 1.00 27.94 C +ATOM 2278 CD1 LEU A 161 16.530 12.740 0.453 1.00 26.95 C +ATOM 2279 CD2 LEU A 161 16.840 10.505 -0.775 1.00 28.87 C +ATOM 2280 H LEU A 161 20.608 10.725 2.416 1.00 23.65 H +ATOM 2281 HA LEU A 161 18.486 12.789 2.464 1.00 23.59 H +ATOM 2282 HB3 LEU A 161 18.833 10.162 0.949 1.00 25.98 H +ATOM 2283 HB2 LEU A 161 19.133 11.741 0.294 1.00 25.98 H +ATOM 2284 HG LEU A 161 16.399 10.772 1.262 1.00 27.94 H +ATOM 2285 HD11 LEU A 161 16.005 12.957 -0.476 1.00 26.95 H +ATOM 2286 HD12 LEU A 161 15.837 12.952 1.268 1.00 26.95 H +ATOM 2287 HD13 LEU A 161 17.345 13.459 0.529 1.00 26.95 H +ATOM 2288 HD21 LEU A 161 16.277 11.069 -1.518 1.00 28.87 H +ATOM 2289 HD22 LEU A 161 17.790 10.223 -1.229 1.00 28.87 H +ATOM 2290 HD23 LEU A 161 16.295 9.582 -0.586 1.00 28.87 H +ATOM 2291 N GLU A 162 16.897 11.549 3.986 1.00 21.39 N +ATOM 2292 CA GLU A 162 16.019 10.906 4.960 1.00 22.91 C +ATOM 2293 C GLU A 162 14.555 11.099 4.593 1.00 21.99 C +ATOM 2294 O GLU A 162 14.198 12.121 4.018 1.00 22.20 O +ATOM 2295 CB GLU A 162 16.314 11.413 6.378 1.00 20.42 C +ATOM 2296 CG GLU A 162 17.813 11.301 6.698 1.00 26.15 C +ATOM 2297 CD GLU A 162 18.207 11.221 8.163 1.00 25.20 C +ATOM 2298 OE1 GLU A 162 19.430 11.100 8.351 1.00 25.08 O +ATOM 2299 OE2 GLU A 162 17.346 11.279 9.067 1.00 25.71 O1- +ATOM 2300 H GLU A 162 16.682 12.509 3.746 1.00 21.39 H +ATOM 2301 HA GLU A 162 16.202 9.834 4.931 1.00 22.91 H +ATOM 2302 HB3 GLU A 162 15.718 10.829 7.081 1.00 20.42 H +ATOM 2303 HB2 GLU A 162 15.992 12.449 6.483 1.00 20.42 H +ATOM 2304 HG3 GLU A 162 18.343 12.141 6.245 1.00 26.15 H +ATOM 2305 HG2 GLU A 162 18.219 10.404 6.234 1.00 26.15 H +ATOM 2306 N ILE A 163 13.748 10.087 4.932 1.00 19.55 N +ATOM 2307 CA ILE A 163 12.349 9.985 4.552 1.00 20.11 C +ATOM 2308 C ILE A 163 11.533 9.827 5.840 1.00 19.59 C +ATOM 2309 O ILE A 163 11.668 8.809 6.516 1.00 19.30 O +ATOM 2310 CB ILE A 163 12.078 8.749 3.638 1.00 21.56 C +ATOM 2311 CG1 ILE A 163 13.127 8.643 2.505 1.00 20.64 C +ATOM 2312 CG2 ILE A 163 10.636 8.778 3.078 1.00 20.03 C +ATOM 2313 CD1 ILE A 163 12.921 7.468 1.546 1.00 22.06 C +ATOM 2314 H ILE A 163 14.131 9.298 5.439 1.00 19.55 H +ATOM 2315 HA ILE A 163 12.029 10.877 4.019 1.00 20.11 H +ATOM 2316 HB ILE A 163 12.171 7.837 4.228 1.00 21.56 H +ATOM 2317 HG13 ILE A 163 14.128 8.540 2.925 1.00 20.64 H +ATOM 2318 HG12 ILE A 163 13.142 9.570 1.940 1.00 20.64 H +ATOM 2319 HG21 ILE A 163 10.416 7.893 2.482 1.00 20.03 H +ATOM 2320 HG22 ILE A 163 9.887 8.806 3.870 1.00 20.03 H +ATOM 2321 HG23 ILE A 163 10.476 9.651 2.444 1.00 20.03 H +ATOM 2322 HD11 ILE A 163 13.870 7.141 1.119 1.00 22.06 H +ATOM 2323 HD12 ILE A 163 12.479 6.616 2.060 1.00 22.06 H +ATOM 2324 HD13 ILE A 163 12.267 7.746 0.721 1.00 22.06 H +ATOM 2325 N TYR A 164 10.696 10.828 6.140 1.00 19.64 N +ATOM 2326 CA TYR A 164 9.721 10.786 7.225 1.00 22.59 C +ATOM 2327 C TYR A 164 8.374 11.223 6.644 1.00 21.43 C +ATOM 2328 O TYR A 164 8.281 12.327 6.108 1.00 23.00 O +ATOM 2329 CB TYR A 164 10.197 11.657 8.411 1.00 18.51 C +ATOM 2330 CG TYR A 164 9.213 11.791 9.564 1.00 20.90 C +ATOM 2331 CD1 TYR A 164 8.145 12.713 9.489 1.00 20.72 C +ATOM 2332 CD2 TYR A 164 9.358 10.989 10.715 1.00 20.94 C +ATOM 2333 CE1 TYR A 164 7.207 12.802 10.533 1.00 23.50 C +ATOM 2334 CE2 TYR A 164 8.437 11.104 11.775 1.00 24.08 C +ATOM 2335 CZ TYR A 164 7.352 11.996 11.676 1.00 23.90 C +ATOM 2336 OH TYR A 164 6.450 12.096 12.694 1.00 25.55 O +ATOM 2337 H TYR A 164 10.647 11.636 5.533 1.00 19.64 H +ATOM 2338 HA TYR A 164 9.611 9.763 7.592 1.00 22.59 H +ATOM 2339 HB3 TYR A 164 10.442 12.660 8.073 1.00 18.51 H +ATOM 2340 HB2 TYR A 164 11.132 11.247 8.795 1.00 18.51 H +ATOM 2341 HD1 TYR A 164 8.033 13.346 8.622 1.00 20.72 H +ATOM 2342 HD2 TYR A 164 10.175 10.287 10.793 1.00 20.94 H +ATOM 2343 HE1 TYR A 164 6.385 13.499 10.459 1.00 23.50 H +ATOM 2344 HE2 TYR A 164 8.559 10.504 12.663 1.00 24.08 H +ATOM 2345 HH TYR A 164 6.727 11.613 13.480 1.00 25.55 H +ATOM 2346 N ASN A 165 7.362 10.345 6.766 1.00 22.76 N +ATOM 2347 CA ASN A 165 5.983 10.536 6.297 1.00 27.93 C +ATOM 2348 C ASN A 165 5.897 10.807 4.774 1.00 25.77 C +ATOM 2349 O ASN A 165 5.116 11.654 4.343 1.00 25.97 O +ATOM 2350 CB ASN A 165 5.284 11.629 7.154 1.00 30.06 C +ATOM 2351 CG ASN A 165 3.753 11.598 7.077 1.00 37.45 C +ATOM 2352 OD1 ASN A 165 3.134 10.551 7.252 1.00 40.14 O +ATOM 2353 ND2 ASN A 165 3.138 12.753 6.813 1.00 39.66 N +ATOM 2354 H ASN A 165 7.538 9.465 7.237 1.00 22.76 H +ATOM 2355 HA ASN A 165 5.457 9.591 6.434 1.00 27.93 H +ATOM 2356 HB3 ASN A 165 5.663 12.622 6.904 1.00 30.06 H +ATOM 2357 HB2 ASN A 165 5.531 11.470 8.204 1.00 30.06 H +ATOM 2358 HD22 ASN A 165 2.132 12.785 6.747 1.00 39.66 H +ATOM 2359 HD21 ASN A 165 3.673 13.595 6.653 1.00 39.66 H +ATOM 2360 N GLU A 166 6.738 10.110 3.987 1.00 25.78 N +ATOM 2361 CA GLU A 166 6.918 10.284 2.536 1.00 27.67 C +ATOM 2362 C GLU A 166 7.451 11.664 2.104 1.00 27.00 C +ATOM 2363 O GLU A 166 7.320 12.014 0.930 1.00 28.61 O +ATOM 2364 CB GLU A 166 5.646 9.878 1.740 1.00 29.56 C +ATOM 2365 CG GLU A 166 5.176 8.430 1.952 1.00 29.68 C +ATOM 2366 CD GLU A 166 6.246 7.410 1.559 1.00 30.08 C +ATOM 2367 OE1 GLU A 166 6.974 6.970 2.473 1.00 27.75 O +ATOM 2368 OE2 GLU A 166 6.325 7.090 0.354 1.00 28.15 O1- +ATOM 2369 H GLU A 166 7.338 9.418 4.415 1.00 25.78 H +ATOM 2370 HA GLU A 166 7.729 9.609 2.263 1.00 27.67 H +ATOM 2371 HB3 GLU A 166 5.813 10.018 0.670 1.00 29.56 H +ATOM 2372 HB2 GLU A 166 4.824 10.550 1.986 1.00 29.56 H +ATOM 2373 HG3 GLU A 166 4.275 8.248 1.365 1.00 29.68 H +ATOM 2374 HG2 GLU A 166 4.885 8.283 2.991 1.00 29.68 H +ATOM 2375 N GLU A 167 8.070 12.407 3.035 1.00 26.94 N +ATOM 2376 CA GLU A 167 8.728 13.677 2.757 1.00 27.18 C +ATOM 2377 C GLU A 167 10.241 13.479 2.866 1.00 28.13 C +ATOM 2378 O GLU A 167 10.716 12.938 3.864 1.00 24.51 O +ATOM 2379 CB GLU A 167 8.249 14.772 3.724 1.00 31.62 C +ATOM 2380 CG GLU A 167 6.712 14.884 3.845 1.00 40.49 C +ATOM 2381 CD GLU A 167 6.180 16.204 4.427 1.00 46.73 C +ATOM 2382 OE1 GLU A 167 6.986 17.113 4.729 1.00 51.21 O +ATOM 2383 OE2 GLU A 167 4.938 16.298 4.528 1.00 50.72 O1- +ATOM 2384 H GLU A 167 8.134 12.074 3.987 1.00 26.94 H +ATOM 2385 HA GLU A 167 8.488 14.013 1.748 1.00 27.18 H +ATOM 2386 HB3 GLU A 167 8.678 15.715 3.380 1.00 31.62 H +ATOM 2387 HB2 GLU A 167 8.656 14.599 4.718 1.00 31.62 H +ATOM 2388 HG3 GLU A 167 6.353 14.073 4.480 1.00 40.49 H +ATOM 2389 HG2 GLU A 167 6.248 14.724 2.872 1.00 40.49 H +ATOM 2390 N LEU A 168 10.955 13.934 1.830 1.00 25.62 N +ATOM 2391 CA LEU A 168 12.407 13.871 1.716 1.00 26.26 C +ATOM 2392 C LEU A 168 13.048 15.068 2.427 1.00 27.12 C +ATOM 2393 O LEU A 168 12.573 16.189 2.263 1.00 27.76 O +ATOM 2394 CB LEU A 168 12.789 13.886 0.225 1.00 26.24 C +ATOM 2395 CG LEU A 168 12.244 12.705 -0.602 1.00 27.75 C +ATOM 2396 CD1 LEU A 168 12.632 12.868 -2.083 1.00 26.99 C +ATOM 2397 CD2 LEU A 168 12.667 11.338 -0.037 1.00 24.52 C +ATOM 2398 H LEU A 168 10.475 14.361 1.048 1.00 25.62 H +ATOM 2399 HA LEU A 168 12.758 12.946 2.169 1.00 26.26 H +ATOM 2400 HB3 LEU A 168 13.875 13.911 0.133 1.00 26.24 H +ATOM 2401 HB2 LEU A 168 12.424 14.812 -0.220 1.00 26.24 H +ATOM 2402 HG LEU A 168 11.154 12.740 -0.564 1.00 27.75 H +ATOM 2403 HD11 LEU A 168 11.737 12.916 -2.701 1.00 26.99 H +ATOM 2404 HD12 LEU A 168 13.192 13.786 -2.264 1.00 26.99 H +ATOM 2405 HD13 LEU A 168 13.246 12.046 -2.452 1.00 26.99 H +ATOM 2406 HD21 LEU A 168 12.868 10.606 -0.817 1.00 24.52 H +ATOM 2407 HD22 LEU A 168 13.567 11.414 0.574 1.00 24.52 H +ATOM 2408 HD23 LEU A 168 11.870 10.926 0.583 1.00 24.52 H +ATOM 2409 N PHE A 169 14.124 14.803 3.177 1.00 27.59 N +ATOM 2410 CA PHE A 169 14.868 15.787 3.954 1.00 28.06 C +ATOM 2411 C PHE A 169 16.367 15.569 3.752 1.00 27.91 C +ATOM 2412 O PHE A 169 16.814 14.435 3.584 1.00 26.56 O +ATOM 2413 CB PHE A 169 14.509 15.657 5.448 1.00 27.08 C +ATOM 2414 CG PHE A 169 13.043 15.882 5.762 1.00 29.27 C +ATOM 2415 CD1 PHE A 169 12.213 14.804 6.134 1.00 26.75 C +ATOM 2416 CD2 PHE A 169 12.467 17.153 5.562 1.00 29.59 C +ATOM 2417 CE1 PHE A 169 10.861 15.027 6.356 1.00 29.38 C +ATOM 2418 CE2 PHE A 169 11.120 17.359 5.817 1.00 29.78 C +ATOM 2419 CZ PHE A 169 10.322 16.299 6.219 1.00 29.34 C +ATOM 2420 H PHE A 169 14.431 13.843 3.280 1.00 27.59 H +ATOM 2421 HA PHE A 169 14.627 16.796 3.611 1.00 28.06 H +ATOM 2422 HB3 PHE A 169 15.077 16.395 6.017 1.00 27.08 H +ATOM 2423 HB2 PHE A 169 14.812 14.681 5.832 1.00 27.08 H +ATOM 2424 HD1 PHE A 169 12.619 13.808 6.238 1.00 26.75 H +ATOM 2425 HD2 PHE A 169 13.070 17.964 5.186 1.00 29.59 H +ATOM 2426 HE1 PHE A 169 10.213 14.210 6.626 1.00 29.38 H +ATOM 2427 HE2 PHE A 169 10.688 18.340 5.677 1.00 29.78 H +ATOM 2428 HZ PHE A 169 9.269 16.457 6.400 1.00 29.34 H +ATOM 2429 N ASP A 170 17.109 16.680 3.802 1.00 28.99 N +ATOM 2430 CA ASP A 170 18.554 16.738 3.668 1.00 31.65 C +ATOM 2431 C ASP A 170 19.115 17.011 5.069 1.00 31.23 C +ATOM 2432 O ASP A 170 18.846 18.070 5.634 1.00 33.73 O +ATOM 2433 CB ASP A 170 18.923 17.840 2.652 1.00 32.63 C +ATOM 2434 CG ASP A 170 20.381 17.900 2.188 1.00 36.16 C +ATOM 2435 OD1 ASP A 170 21.291 17.440 2.913 1.00 37.04 O +ATOM 2436 OD2 ASP A 170 20.576 18.543 1.139 1.00 37.99 O1- +ATOM 2437 H ASP A 170 16.659 17.570 3.984 1.00 28.99 H +ATOM 2438 HA ASP A 170 18.941 15.785 3.299 1.00 31.65 H +ATOM 2439 HB3 ASP A 170 18.651 18.819 3.054 1.00 32.63 H +ATOM 2440 HB2 ASP A 170 18.289 17.729 1.774 1.00 32.63 H +ATOM 2441 N LEU A 171 19.872 16.041 5.600 1.00 32.05 N +ATOM 2442 CA LEU A 171 20.402 16.076 6.962 1.00 33.78 C +ATOM 2443 C LEU A 171 21.898 16.424 7.024 1.00 36.20 C +ATOM 2444 O LEU A 171 22.421 16.452 8.135 1.00 37.78 O +ATOM 2445 CB LEU A 171 20.058 14.747 7.678 1.00 31.15 C +ATOM 2446 CG LEU A 171 18.695 14.759 8.402 1.00 31.77 C +ATOM 2447 CD1 LEU A 171 18.679 15.685 9.621 1.00 29.95 C +ATOM 2448 CD2 LEU A 171 17.497 14.983 7.464 1.00 27.08 C +ATOM 2449 H LEU A 171 20.055 15.200 5.068 1.00 32.05 H +ATOM 2450 HA LEU A 171 19.925 16.881 7.523 1.00 33.78 H +ATOM 2451 HB3 LEU A 171 20.814 14.496 8.422 1.00 31.15 H +ATOM 2452 HB2 LEU A 171 20.079 13.929 6.960 1.00 31.15 H +ATOM 2453 HG LEU A 171 18.586 13.765 8.822 1.00 31.77 H +ATOM 2454 HD11 LEU A 171 18.104 15.244 10.434 1.00 29.95 H +ATOM 2455 HD12 LEU A 171 19.685 15.874 9.993 1.00 29.95 H +ATOM 2456 HD13 LEU A 171 18.226 16.642 9.385 1.00 29.95 H +ATOM 2457 HD21 LEU A 171 16.625 14.435 7.814 1.00 27.08 H +ATOM 2458 HD22 LEU A 171 17.217 16.034 7.401 1.00 27.08 H +ATOM 2459 HD23 LEU A 171 17.703 14.632 6.453 1.00 27.08 H +ATOM 2460 N LEU A 172 22.550 16.751 5.892 1.00 38.78 N +ATOM 2461 CA LEU A 172 23.935 17.241 5.883 1.00 42.77 C +ATOM 2462 C LEU A 172 24.066 18.716 5.474 1.00 44.63 C +ATOM 2463 O LEU A 172 25.080 19.299 5.852 1.00 46.83 O +ATOM 2464 CB LEU A 172 24.832 16.352 4.992 1.00 39.05 C +ATOM 2465 CG LEU A 172 25.307 15.037 5.645 1.00 37.98 C +ATOM 2466 CD1 LEU A 172 26.123 14.192 4.643 1.00 35.12 C +ATOM 2467 CD2 LEU A 172 26.075 15.258 6.962 1.00 35.36 C +ATOM 2468 H LEU A 172 22.069 16.724 5.002 1.00 38.78 H +ATOM 2469 HA LEU A 172 24.344 17.220 6.893 1.00 42.77 H +ATOM 2470 HB3 LEU A 172 25.727 16.901 4.703 1.00 39.05 H +ATOM 2471 HB2 LEU A 172 24.313 16.142 4.059 1.00 39.05 H +ATOM 2472 HG LEU A 172 24.424 14.469 5.913 1.00 37.98 H +ATOM 2473 HD11 LEU A 172 25.708 13.191 4.535 1.00 35.12 H +ATOM 2474 HD12 LEU A 172 26.142 14.639 3.649 1.00 35.12 H +ATOM 2475 HD13 LEU A 172 27.162 14.073 4.950 1.00 35.12 H +ATOM 2476 HD21 LEU A 172 26.871 14.529 7.105 1.00 35.36 H +ATOM 2477 HD22 LEU A 172 26.525 16.250 7.011 1.00 35.36 H +ATOM 2478 HD23 LEU A 172 25.406 15.157 7.815 1.00 35.36 H +ATOM 2479 N ASN A 173 23.092 19.302 4.748 1.00 48.64 N +ATOM 2480 CA ASN A 173 23.133 20.692 4.261 1.00 51.22 C +ATOM 2481 C ASN A 173 23.265 21.701 5.426 1.00 53.10 C +ATOM 2482 O ASN A 173 22.304 21.851 6.180 1.00 51.10 O +ATOM 2483 CB ASN A 173 21.855 20.967 3.432 1.00 53.38 C +ATOM 2484 CG ASN A 173 21.805 22.326 2.717 1.00 55.13 C +ATOM 2485 OD1 ASN A 173 22.729 23.131 2.801 1.00 57.22 O +ATOM 2486 ND2 ASN A 173 20.729 22.571 1.970 1.00 54.72 N +ATOM 2487 H ASN A 173 22.302 18.749 4.439 1.00 48.64 H +ATOM 2488 HA ASN A 173 23.978 20.739 3.576 1.00 51.22 H +ATOM 2489 HB3 ASN A 173 20.953 20.828 4.030 1.00 53.38 H +ATOM 2490 HB2 ASN A 173 21.824 20.230 2.638 1.00 53.38 H +ATOM 2491 HD22 ASN A 173 20.662 23.429 1.441 1.00 54.72 H +ATOM 2492 HD21 ASN A 173 20.003 21.875 1.876 1.00 54.72 H +ATOM 2493 N PRO A 174 24.427 22.381 5.556 1.00 55.43 N +ATOM 2494 CA PRO A 174 24.622 23.370 6.626 1.00 55.93 C +ATOM 2495 C PRO A 174 23.961 24.738 6.347 1.00 56.43 C +ATOM 2496 O PRO A 174 23.924 25.563 7.259 1.00 57.87 O +ATOM 2497 CB PRO A 174 26.151 23.476 6.701 1.00 56.37 C +ATOM 2498 CG PRO A 174 26.603 23.310 5.258 1.00 57.18 C +ATOM 2499 CD PRO A 174 25.612 22.296 4.692 1.00 55.65 C +ATOM 2500 HA PRO A 174 24.239 22.998 7.578 1.00 55.93 H +ATOM 2501 HB3 PRO A 174 26.540 22.654 7.305 1.00 56.37 H +ATOM 2502 HB2 PRO A 174 26.509 24.405 7.147 1.00 56.37 H +ATOM 2503 HG3 PRO A 174 27.642 22.996 5.162 1.00 57.18 H +ATOM 2504 HG2 PRO A 174 26.492 24.260 4.733 1.00 57.18 H +ATOM 2505 HD2 PRO A 174 25.383 22.520 3.649 1.00 55.65 H +ATOM 2506 HD3 PRO A 174 26.043 21.298 4.737 1.00 55.65 H +ATOM 2507 N SER A 175 23.478 24.962 5.110 1.00 56.90 N +ATOM 2508 CA SER A 175 22.917 26.234 4.655 1.00 57.82 C +ATOM 2509 C SER A 175 21.427 26.351 5.007 1.00 58.21 C +ATOM 2510 O SER A 175 21.030 27.361 5.587 1.00 59.23 O +ATOM 2511 CB SER A 175 23.116 26.386 3.132 1.00 58.15 C +ATOM 2512 OG SER A 175 24.487 26.344 2.795 1.00 58.20 O +ATOM 2513 H SER A 175 23.525 24.227 4.417 1.00 56.90 H +ATOM 2514 HA SER A 175 23.447 27.053 5.146 1.00 57.82 H +ATOM 2515 HB3 SER A 175 22.720 27.346 2.798 1.00 58.15 H +ATOM 2516 HB2 SER A 175 22.582 25.622 2.569 1.00 58.15 H +ATOM 2517 HG SER A 175 24.795 25.438 2.878 1.00 58.20 H +ATOM 2518 N SER A 176 20.641 25.321 4.652 1.00 58.11 N +ATOM 2519 CA SER A 176 19.201 25.264 4.893 1.00 57.43 C +ATOM 2520 C SER A 176 18.903 24.357 6.097 1.00 57.06 C +ATOM 2521 O SER A 176 19.651 23.416 6.358 1.00 56.98 O +ATOM 2522 CB SER A 176 18.519 24.749 3.613 1.00 58.25 C +ATOM 2523 OG SER A 176 17.116 24.806 3.721 1.00 59.33 O +ATOM 2524 H SER A 176 21.050 24.514 4.205 1.00 58.11 H +ATOM 2525 HA SER A 176 18.816 26.263 5.106 1.00 57.43 H +ATOM 2526 HB3 SER A 176 18.800 23.716 3.414 1.00 58.25 H +ATOM 2527 HB2 SER A 176 18.821 25.342 2.748 1.00 58.25 H +ATOM 2528 HG SER A 176 16.809 25.690 3.498 1.00 59.33 H +ATOM 2529 N ASP A 177 17.790 24.649 6.786 1.00 56.57 N +ATOM 2530 CA ASP A 177 17.235 23.873 7.901 1.00 57.04 C +ATOM 2531 C ASP A 177 16.579 22.562 7.423 1.00 55.49 C +ATOM 2532 O ASP A 177 16.300 22.407 6.233 1.00 54.80 O +ATOM 2533 CB ASP A 177 16.266 24.712 8.788 1.00 59.67 C +ATOM 2534 CG ASP A 177 15.378 25.748 8.070 1.00 62.71 C +ATOM 2535 OD1 ASP A 177 14.852 25.430 6.979 1.00 63.65 O +ATOM 2536 OD2 ASP A 177 15.145 26.810 8.686 1.00 64.94 O1- +ATOM 2537 H ASP A 177 17.208 25.413 6.470 1.00 56.57 H +ATOM 2538 HA ASP A 177 18.079 23.589 8.533 1.00 57.04 H +ATOM 2539 HB3 ASP A 177 16.863 25.222 9.546 1.00 59.67 H +ATOM 2540 HB2 ASP A 177 15.595 24.060 9.350 1.00 59.67 H +ATOM 2541 N VAL A 178 16.343 21.634 8.367 1.00 53.79 N +ATOM 2542 CA VAL A 178 15.723 20.332 8.095 1.00 52.83 C +ATOM 2543 C VAL A 178 14.278 20.406 7.574 1.00 52.35 C +ATOM 2544 O VAL A 178 13.897 19.522 6.816 1.00 53.10 O +ATOM 2545 CB VAL A 178 15.698 19.406 9.336 1.00 52.72 C +ATOM 2546 CG1 VAL A 178 17.108 19.092 9.820 1.00 52.31 C +ATOM 2547 CG2 VAL A 178 14.819 19.901 10.498 1.00 53.46 C +ATOM 2548 H VAL A 178 16.580 21.823 9.330 1.00 53.79 H +ATOM 2549 HA VAL A 178 16.325 19.847 7.324 1.00 52.83 H +ATOM 2550 HB VAL A 178 15.286 18.445 9.020 1.00 52.72 H +ATOM 2551 HG11 VAL A 178 17.080 18.289 10.550 1.00 52.31 H +ATOM 2552 HG12 VAL A 178 17.740 18.772 8.992 1.00 52.31 H +ATOM 2553 HG13 VAL A 178 17.567 19.958 10.294 1.00 52.31 H +ATOM 2554 HG21 VAL A 178 14.971 19.292 11.385 1.00 53.46 H +ATOM 2555 HG22 VAL A 178 15.050 20.931 10.768 1.00 53.46 H +ATOM 2556 HG23 VAL A 178 13.760 19.839 10.251 1.00 53.46 H +ATOM 2557 N SER A 179 13.519 21.448 7.957 1.00 51.84 N +ATOM 2558 CA SER A 179 12.134 21.677 7.532 1.00 50.53 C +ATOM 2559 C SER A 179 11.957 21.927 6.020 1.00 49.55 C +ATOM 2560 O SER A 179 10.836 21.802 5.527 1.00 48.64 O +ATOM 2561 CB SER A 179 11.533 22.809 8.390 1.00 50.49 C +ATOM 2562 OG SER A 179 12.186 24.046 8.186 1.00 49.66 O +ATOM 2563 H SER A 179 13.912 22.160 8.556 1.00 51.84 H +ATOM 2564 HA SER A 179 11.578 20.766 7.760 1.00 50.53 H +ATOM 2565 HB3 SER A 179 11.590 22.553 9.447 1.00 50.49 H +ATOM 2566 HB2 SER A 179 10.474 22.936 8.160 1.00 50.49 H +ATOM 2567 HG SER A 179 12.054 24.334 7.279 1.00 49.66 H +ATOM 2568 N GLU A 180 13.058 22.246 5.319 1.00 49.36 N +ATOM 2569 CA GLU A 180 13.113 22.473 3.882 1.00 49.04 C +ATOM 2570 C GLU A 180 13.111 21.123 3.140 1.00 48.31 C +ATOM 2571 O GLU A 180 14.169 20.533 2.924 1.00 48.45 O +ATOM 2572 CB GLU A 180 14.378 23.308 3.597 1.00 51.29 C +ATOM 2573 CG GLU A 180 14.324 24.086 2.267 1.00 55.71 C +ATOM 2574 CD GLU A 180 13.886 25.541 2.488 1.00 58.55 C +ATOM 2575 OE1 GLU A 180 12.722 25.737 2.906 1.00 58.48 O +ATOM 2576 OE2 GLU A 180 14.726 26.437 2.249 1.00 58.81 O1- +ATOM 2577 H GLU A 180 13.940 22.333 5.806 1.00 49.36 H +ATOM 2578 HA GLU A 180 12.232 23.049 3.590 1.00 49.04 H +ATOM 2579 HB3 GLU A 180 15.264 22.673 3.589 1.00 51.29 H +ATOM 2580 HB2 GLU A 180 14.559 23.996 4.426 1.00 51.29 H +ATOM 2581 HG3 GLU A 180 13.648 23.606 1.558 1.00 55.71 H +ATOM 2582 HG2 GLU A 180 15.307 24.066 1.794 1.00 55.71 H +ATOM 2583 N ARG A 181 11.908 20.641 2.795 1.00 46.01 N +ATOM 2584 CA ARG A 181 11.706 19.364 2.113 1.00 46.71 C +ATOM 2585 C ARG A 181 12.213 19.394 0.656 1.00 45.19 C +ATOM 2586 O ARG A 181 12.084 20.415 -0.022 1.00 45.10 O +ATOM 2587 CB ARG A 181 10.220 18.964 2.224 1.00 48.88 C +ATOM 2588 CG ARG A 181 9.244 19.850 1.418 1.00 53.95 C +ATOM 2589 CD ARG A 181 7.754 19.627 1.735 1.00 58.90 C +ATOM 2590 NE ARG A 181 7.311 18.229 1.586 1.00 62.40 N +ATOM 2591 CZ ARG A 181 7.171 17.509 0.457 1.00 63.28 C +ATOM 2592 NH1 ARG A 181 7.504 17.984 -0.753 1.00 64.77 N +ATOM 2593 NH2 ARG A 181 6.678 16.268 0.547 1.00 63.18 N1+ +ATOM 2594 H ARG A 181 11.077 21.165 3.030 1.00 46.01 H +ATOM 2595 HA ARG A 181 12.289 18.630 2.669 1.00 46.71 H +ATOM 2596 HB3 ARG A 181 9.929 18.968 3.275 1.00 48.88 H +ATOM 2597 HB2 ARG A 181 10.117 17.929 1.894 1.00 48.88 H +ATOM 2598 HG3 ARG A 181 9.426 19.814 0.344 1.00 53.95 H +ATOM 2599 HG2 ARG A 181 9.457 20.880 1.705 1.00 53.95 H +ATOM 2600 HD3 ARG A 181 7.165 20.192 1.013 1.00 58.90 H +ATOM 2601 HD2 ARG A 181 7.489 20.033 2.712 1.00 58.90 H +ATOM 2602 HE ARG A 181 7.090 17.776 2.466 1.00 62.40 H +ATOM 2603 HH12 ARG A 181 7.380 17.423 -1.583 1.00 64.77 H +ATOM 2604 HH11 ARG A 181 7.879 18.918 -0.836 1.00 64.77 H +ATOM 2605 HH22 ARG A 181 6.537 15.704 -0.278 1.00 63.18 H +ATOM 2606 HH21 ARG A 181 6.397 15.901 1.447 1.00 63.18 H +ATOM 2607 N LEU A 182 12.770 18.259 0.209 1.00 41.92 N +ATOM 2608 CA LEU A 182 13.299 18.066 -1.143 1.00 39.89 C +ATOM 2609 C LEU A 182 12.213 17.500 -2.073 1.00 38.35 C +ATOM 2610 O LEU A 182 11.207 16.974 -1.598 1.00 38.67 O +ATOM 2611 CB LEU A 182 14.511 17.107 -1.092 1.00 40.08 C +ATOM 2612 CG LEU A 182 15.627 17.483 -0.091 1.00 39.80 C +ATOM 2613 CD1 LEU A 182 16.759 16.436 -0.147 1.00 39.86 C +ATOM 2614 CD2 LEU A 182 16.149 18.923 -0.282 1.00 39.90 C +ATOM 2615 H LEU A 182 12.827 17.461 0.829 1.00 41.92 H +ATOM 2616 HA LEU A 182 13.623 19.025 -1.551 1.00 39.89 H +ATOM 2617 HB3 LEU A 182 14.946 17.033 -2.090 1.00 40.08 H +ATOM 2618 HB2 LEU A 182 14.167 16.103 -0.852 1.00 40.08 H +ATOM 2619 HG LEU A 182 15.209 17.425 0.915 1.00 39.80 H +ATOM 2620 HD11 LEU A 182 16.928 15.991 0.834 1.00 39.86 H +ATOM 2621 HD12 LEU A 182 16.529 15.616 -0.827 1.00 39.86 H +ATOM 2622 HD13 LEU A 182 17.704 16.860 -0.480 1.00 39.86 H +ATOM 2623 HD21 LEU A 182 17.227 18.999 -0.141 1.00 39.90 H +ATOM 2624 HD22 LEU A 182 15.931 19.308 -1.278 1.00 39.90 H +ATOM 2625 HD23 LEU A 182 15.688 19.597 0.441 1.00 39.90 H +ATOM 2626 N GLN A 183 12.449 17.604 -3.387 1.00 36.55 N +ATOM 2627 CA GLN A 183 11.569 17.071 -4.429 1.00 36.23 C +ATOM 2628 C GLN A 183 12.327 15.986 -5.198 1.00 33.70 C +ATOM 2629 O GLN A 183 13.508 16.181 -5.482 1.00 32.46 O +ATOM 2630 CB GLN A 183 11.155 18.217 -5.375 1.00 40.21 C +ATOM 2631 CG GLN A 183 10.294 19.294 -4.686 1.00 46.32 C +ATOM 2632 CD GLN A 183 10.070 20.524 -5.567 1.00 51.85 C +ATOM 2633 OE1 GLN A 183 9.771 20.409 -6.753 1.00 53.00 O +ATOM 2634 NE2 GLN A 183 10.189 21.717 -4.981 1.00 54.16 N +ATOM 2635 H GLN A 183 13.312 18.021 -3.708 1.00 36.55 H +ATOM 2636 HA GLN A 183 10.668 16.627 -4.002 1.00 36.23 H +ATOM 2637 HB3 GLN A 183 10.599 17.807 -6.220 1.00 40.21 H +ATOM 2638 HB2 GLN A 183 12.049 18.680 -5.798 1.00 40.21 H +ATOM 2639 HG3 GLN A 183 10.767 19.618 -3.758 1.00 46.32 H +ATOM 2640 HG2 GLN A 183 9.325 18.877 -4.409 1.00 46.32 H +ATOM 2641 HE22 GLN A 183 10.020 22.560 -5.510 1.00 54.16 H +ATOM 2642 HE21 GLN A 183 10.426 21.786 -4.002 1.00 54.16 H +ATOM 2643 N MET A 184 11.634 14.890 -5.554 1.00 32.15 N +ATOM 2644 CA MET A 184 12.185 13.854 -6.428 1.00 35.07 C +ATOM 2645 C MET A 184 11.328 13.685 -7.684 1.00 35.72 C +ATOM 2646 O MET A 184 10.109 13.860 -7.649 1.00 34.61 O +ATOM 2647 CB MET A 184 12.407 12.522 -5.682 1.00 34.84 C +ATOM 2648 CG MET A 184 11.141 11.723 -5.318 1.00 38.74 C +ATOM 2649 SD MET A 184 11.469 10.099 -4.586 1.00 41.75 S +ATOM 2650 CE MET A 184 12.019 9.209 -6.055 1.00 40.67 C +ATOM 2651 H MET A 184 10.658 14.802 -5.315 1.00 32.15 H +ATOM 2652 HA MET A 184 13.162 14.185 -6.768 1.00 35.07 H +ATOM 2653 HB3 MET A 184 12.998 12.711 -4.787 1.00 34.84 H +ATOM 2654 HB2 MET A 184 13.047 11.899 -6.306 1.00 34.84 H +ATOM 2655 HG3 MET A 184 10.513 11.553 -6.192 1.00 38.74 H +ATOM 2656 HG2 MET A 184 10.539 12.299 -4.616 1.00 38.74 H +ATOM 2657 HE1 MET A 184 12.197 8.162 -5.816 1.00 40.67 H +ATOM 2658 HE2 MET A 184 11.275 9.266 -6.846 1.00 40.67 H +ATOM 2659 HE3 MET A 184 12.946 9.641 -6.425 1.00 40.67 H +ATOM 2660 N PHE A 185 12.027 13.326 -8.765 1.00 38.29 N +ATOM 2661 CA PHE A 185 11.511 13.112 -10.109 1.00 42.79 C +ATOM 2662 C PHE A 185 12.190 11.854 -10.660 1.00 44.70 C +ATOM 2663 O PHE A 185 13.246 11.458 -10.169 1.00 44.77 O +ATOM 2664 CB PHE A 185 11.885 14.325 -10.993 1.00 43.13 C +ATOM 2665 CG PHE A 185 11.475 15.680 -10.444 1.00 43.75 C +ATOM 2666 CD1 PHE A 185 12.364 16.403 -9.619 1.00 43.96 C +ATOM 2667 CD2 PHE A 185 10.152 16.142 -10.600 1.00 44.55 C +ATOM 2668 CE1 PHE A 185 11.950 17.586 -9.023 1.00 44.32 C +ATOM 2669 CE2 PHE A 185 9.760 17.332 -10.002 1.00 45.42 C +ATOM 2670 CZ PHE A 185 10.658 18.052 -9.225 1.00 45.48 C +ATOM 2671 H PHE A 185 13.027 13.195 -8.672 1.00 38.29 H +ATOM 2672 HA PHE A 185 10.429 12.968 -10.092 1.00 42.79 H +ATOM 2673 HB3 PHE A 185 11.422 14.208 -11.975 1.00 43.13 H +ATOM 2674 HB2 PHE A 185 12.962 14.343 -11.174 1.00 43.13 H +ATOM 2675 HD1 PHE A 185 13.365 16.035 -9.441 1.00 43.96 H +ATOM 2676 HD2 PHE A 185 9.442 15.574 -11.185 1.00 44.55 H +ATOM 2677 HE1 PHE A 185 12.632 18.143 -8.397 1.00 44.32 H +ATOM 2678 HE2 PHE A 185 8.752 17.694 -10.134 1.00 45.42 H +ATOM 2679 HZ PHE A 185 10.344 18.976 -8.766 1.00 45.48 H +ATOM 2680 N ASP A 186 11.608 11.273 -11.714 1.00 49.80 N +ATOM 2681 CA ASP A 186 12.247 10.204 -12.488 1.00 53.56 C +ATOM 2682 C ASP A 186 13.375 10.786 -13.350 1.00 53.93 C +ATOM 2683 O ASP A 186 13.199 11.856 -13.933 1.00 53.64 O +ATOM 2684 CB ASP A 186 11.238 9.432 -13.367 1.00 56.42 C +ATOM 2685 CG ASP A 186 10.033 8.857 -12.608 1.00 58.79 C +ATOM 2686 OD1 ASP A 186 9.009 8.610 -13.280 1.00 61.00 O +ATOM 2687 OD2 ASP A 186 10.179 8.532 -11.406 1.00 60.88 O1- +ATOM 2688 H ASP A 186 10.743 11.638 -12.085 1.00 49.80 H +ATOM 2689 HA ASP A 186 12.695 9.493 -11.790 1.00 53.56 H +ATOM 2690 HB3 ASP A 186 11.742 8.602 -13.863 1.00 56.42 H +ATOM 2691 HB2 ASP A 186 10.860 10.092 -14.151 1.00 56.42 H +ATOM 2692 N ASP A 187 14.506 10.066 -13.412 1.00 55.24 N +ATOM 2693 CA ASP A 187 15.660 10.426 -14.235 1.00 58.13 C +ATOM 2694 C ASP A 187 15.295 10.136 -15.712 1.00 59.52 C +ATOM 2695 O ASP A 187 14.926 8.996 -15.999 1.00 59.93 O +ATOM 2696 CB ASP A 187 16.911 9.644 -13.752 1.00 58.39 C +ATOM 2697 CG ASP A 187 18.283 10.085 -14.307 1.00 59.33 C +ATOM 2698 OD1 ASP A 187 18.375 10.537 -15.470 1.00 60.74 O +ATOM 2699 OD2 ASP A 187 19.271 9.846 -13.580 1.00 60.02 O1- +ATOM 2700 H ASP A 187 14.570 9.185 -12.921 1.00 55.24 H +ATOM 2701 HA ASP A 187 15.863 11.477 -14.052 1.00 58.13 H +ATOM 2702 HB3 ASP A 187 16.784 8.582 -13.960 1.00 58.39 H +ATOM 2703 HB2 ASP A 187 16.948 9.704 -12.663 1.00 58.39 H +ATOM 2704 N PRO A 188 15.387 11.151 -16.613 1.00 60.65 N +ATOM 2705 CA PRO A 188 15.169 10.977 -18.066 1.00 62.13 C +ATOM 2706 C PRO A 188 15.918 9.815 -18.748 1.00 63.15 C +ATOM 2707 O PRO A 188 15.374 9.233 -19.685 1.00 63.29 O +ATOM 2708 CB PRO A 188 15.589 12.328 -18.669 1.00 62.23 C +ATOM 2709 CG PRO A 188 15.324 13.330 -17.563 1.00 61.55 C +ATOM 2710 CD PRO A 188 15.690 12.553 -16.309 1.00 60.85 C +ATOM 2711 HA PRO A 188 14.096 10.835 -18.208 1.00 62.13 H +ATOM 2712 HB3 PRO A 188 15.044 12.568 -19.582 1.00 62.23 H +ATOM 2713 HB2 PRO A 188 16.654 12.331 -18.909 1.00 62.23 H +ATOM 2714 HG3 PRO A 188 14.260 13.571 -17.542 1.00 61.55 H +ATOM 2715 HG2 PRO A 188 15.879 14.262 -17.675 1.00 61.55 H +ATOM 2716 HD2 PRO A 188 16.757 12.650 -16.110 1.00 60.85 H +ATOM 2717 HD3 PRO A 188 15.132 12.945 -15.459 1.00 60.85 H +ATOM 2718 N ARG A 189 17.128 9.495 -18.256 1.00 64.44 N +ATOM 2719 CA ARG A 189 17.941 8.367 -18.704 1.00 65.37 C +ATOM 2720 C ARG A 189 17.538 7.090 -17.948 1.00 66.47 C +ATOM 2721 O ARG A 189 16.638 6.387 -18.409 1.00 66.61 O +ATOM 2722 CB ARG A 189 19.440 8.703 -18.541 1.00 65.44 C +ATOM 2723 CG ARG A 189 19.894 9.938 -19.326 1.00 66.51 C +ATOM 2724 CD ARG A 189 21.406 10.165 -19.175 1.00 66.86 C +ATOM 2725 NE ARG A 189 21.821 11.485 -19.674 1.00 66.26 N +ATOM 2726 CZ ARG A 189 21.719 12.656 -19.015 1.00 66.65 C +ATOM 2727 NH1 ARG A 189 21.194 12.743 -17.781 1.00 66.57 N +ATOM 2728 NH2 ARG A 189 22.156 13.771 -19.612 1.00 65.04 N1+ +ATOM 2729 H ARG A 189 17.492 10.010 -17.464 1.00 64.44 H +ATOM 2730 HA ARG A 189 17.758 8.189 -19.766 1.00 65.37 H +ATOM 2731 HB3 ARG A 189 20.039 7.845 -18.853 1.00 65.44 H +ATOM 2732 HB2 ARG A 189 19.674 8.874 -17.489 1.00 65.44 H +ATOM 2733 HG3 ARG A 189 19.318 10.832 -19.082 1.00 66.51 H +ATOM 2734 HG2 ARG A 189 19.686 9.721 -20.375 1.00 66.51 H +ATOM 2735 HD3 ARG A 189 21.914 9.469 -19.843 1.00 66.86 H +ATOM 2736 HD2 ARG A 189 21.777 9.943 -18.174 1.00 66.86 H +ATOM 2737 HE ARG A 189 22.187 11.498 -20.615 1.00 66.26 H +ATOM 2738 HH12 ARG A 189 21.130 13.631 -17.306 1.00 66.57 H +ATOM 2739 HH11 ARG A 189 20.850 11.912 -17.318 1.00 66.57 H +ATOM 2740 HH22 ARG A 189 22.091 14.662 -19.141 1.00 65.04 H +ATOM 2741 HH21 ARG A 189 22.555 13.734 -20.539 1.00 65.04 H +ATOM 2742 N ASN A 190 18.237 6.806 -16.833 1.00 66.58 N +ATOM 2743 CA ASN A 190 18.134 5.599 -16.007 1.00 66.84 C +ATOM 2744 C ASN A 190 16.696 5.336 -15.546 1.00 66.83 C +ATOM 2745 O ASN A 190 16.134 6.142 -14.806 1.00 66.79 O +ATOM 2746 CB ASN A 190 19.070 5.736 -14.780 1.00 67.44 C +ATOM 2747 CG ASN A 190 20.569 5.739 -15.104 1.00 68.51 C +ATOM 2748 OD1 ASN A 190 20.992 5.373 -16.199 1.00 68.94 O +ATOM 2749 ND2 ASN A 190 21.388 6.142 -14.130 1.00 68.38 N +ATOM 2750 H ASN A 190 18.941 7.465 -16.533 1.00 66.58 H +ATOM 2751 HA ASN A 190 18.479 4.775 -16.636 1.00 66.84 H +ATOM 2752 HB3 ASN A 190 18.901 4.901 -14.098 1.00 67.44 H +ATOM 2753 HB2 ASN A 190 18.825 6.643 -14.224 1.00 67.44 H +ATOM 2754 HD22 ASN A 190 22.385 6.160 -14.286 1.00 68.38 H +ATOM 2755 HD21 ASN A 190 21.018 6.451 -13.243 1.00 68.38 H +ATOM 2756 N LYS A 191 16.145 4.198 -15.991 1.00 66.99 N +ATOM 2757 CA LYS A 191 14.784 3.760 -15.671 1.00 67.22 C +ATOM 2758 C LYS A 191 14.638 3.258 -14.222 1.00 66.45 C +ATOM 2759 O LYS A 191 13.533 3.302 -13.683 1.00 65.12 O +ATOM 2760 CB LYS A 191 14.349 2.676 -16.675 1.00 68.00 C +ATOM 2761 CG LYS A 191 14.388 3.157 -18.140 1.00 69.16 C +ATOM 2762 CD LYS A 191 13.687 2.212 -19.128 1.00 69.10 C +ATOM 2763 CE LYS A 191 12.152 2.257 -19.017 1.00 69.33 C +ATOM 2764 NZ LYS A 191 11.504 1.395 -20.020 1.00 70.64 N1+ +ATOM 2765 H LYS A 191 16.671 3.600 -16.611 1.00 66.99 H +ATOM 2766 HA LYS A 191 14.117 4.617 -15.785 1.00 67.22 H +ATOM 2767 HB3 LYS A 191 13.336 2.365 -16.419 1.00 68.00 H +ATOM 2768 HB2 LYS A 191 14.973 1.788 -16.570 1.00 68.00 H +ATOM 2769 HG3 LYS A 191 15.427 3.272 -18.450 1.00 69.16 H +ATOM 2770 HG2 LYS A 191 13.946 4.152 -18.216 1.00 69.16 H +ATOM 2771 HD3 LYS A 191 14.042 1.193 -18.961 1.00 69.10 H +ATOM 2772 HD2 LYS A 191 13.995 2.476 -20.140 1.00 69.10 H +ATOM 2773 HE3 LYS A 191 11.795 3.278 -19.160 1.00 69.33 H +ATOM 2774 HE2 LYS A 191 11.820 1.937 -18.030 1.00 69.33 H +ATOM 2775 HZ1 LYS A 191 11.795 0.438 -19.884 1.00 70.64 H +ATOM 2776 HZ2 LYS A 191 10.500 1.457 -19.921 1.00 70.64 H +ATOM 2777 HZ3 LYS A 191 11.768 1.698 -20.947 1.00 70.64 H +ATOM 2778 N ARG A 192 15.758 2.817 -13.624 1.00 66.07 N +ATOM 2779 CA ARG A 192 15.870 2.398 -12.226 1.00 65.07 C +ATOM 2780 C ARG A 192 16.387 3.527 -11.313 1.00 63.80 C +ATOM 2781 O ARG A 192 16.500 3.310 -10.106 1.00 64.94 O +ATOM 2782 CB ARG A 192 16.781 1.154 -12.141 1.00 65.08 C +ATOM 2783 CG ARG A 192 16.354 0.029 -13.106 1.00 65.38 C +ATOM 2784 CD ARG A 192 17.045 -1.325 -12.868 1.00 64.94 C +ATOM 2785 NE ARG A 192 16.612 -1.982 -11.621 1.00 63.91 N +ATOM 2786 CZ ARG A 192 15.437 -2.598 -11.387 1.00 65.68 C +ATOM 2787 NH1 ARG A 192 14.472 -2.687 -12.315 1.00 64.31 N +ATOM 2788 NH2 ARG A 192 15.218 -3.147 -10.188 1.00 65.10 N1+ +ATOM 2789 H ARG A 192 16.619 2.820 -14.150 1.00 66.07 H +ATOM 2790 HA ARG A 192 14.884 2.117 -11.857 1.00 65.07 H +ATOM 2791 HB3 ARG A 192 16.782 0.784 -11.115 1.00 65.08 H +ATOM 2792 HB2 ARG A 192 17.813 1.432 -12.363 1.00 65.08 H +ATOM 2793 HG3 ARG A 192 16.453 0.313 -14.153 1.00 65.38 H +ATOM 2794 HG2 ARG A 192 15.282 -0.096 -12.947 1.00 65.38 H +ATOM 2795 HD3 ARG A 192 18.107 -1.133 -12.717 1.00 64.94 H +ATOM 2796 HD2 ARG A 192 16.986 -1.979 -13.739 1.00 64.94 H +ATOM 2797 HE ARG A 192 17.285 -1.929 -10.868 1.00 63.91 H +ATOM 2798 HH12 ARG A 192 13.592 -3.134 -12.099 1.00 64.31 H +ATOM 2799 HH11 ARG A 192 14.604 -2.267 -13.223 1.00 64.31 H +ATOM 2800 HH22 ARG A 192 14.344 -3.614 -9.984 1.00 65.10 H +ATOM 2801 HH21 ARG A 192 15.898 -3.059 -9.446 1.00 65.10 H +ATOM 2802 N GLY A 193 16.702 4.693 -11.905 1.00 61.68 N +ATOM 2803 CA GLY A 193 17.254 5.858 -11.229 1.00 57.85 C +ATOM 2804 C GLY A 193 16.195 6.959 -11.119 1.00 54.40 C +ATOM 2805 O GLY A 193 15.203 6.988 -11.851 1.00 54.74 O +ATOM 2806 H GLY A 193 16.527 4.797 -12.895 1.00 61.68 H +ATOM 2807 HA3 GLY A 193 18.090 6.238 -11.817 1.00 57.85 H +ATOM 2808 HA2 GLY A 193 17.645 5.607 -10.242 1.00 57.85 H +ATOM 2809 N VAL A 194 16.460 7.887 -10.193 1.00 51.20 N +ATOM 2810 CA VAL A 194 15.654 9.067 -9.903 1.00 47.88 C +ATOM 2811 C VAL A 194 16.595 10.258 -9.641 1.00 45.73 C +ATOM 2812 O VAL A 194 17.732 10.067 -9.208 1.00 44.54 O +ATOM 2813 CB VAL A 194 14.747 8.844 -8.654 1.00 48.42 C +ATOM 2814 CG1 VAL A 194 13.683 7.760 -8.910 1.00 48.70 C +ATOM 2815 CG2 VAL A 194 15.511 8.570 -7.342 1.00 48.70 C +ATOM 2816 H VAL A 194 17.309 7.814 -9.651 1.00 51.20 H +ATOM 2817 HA VAL A 194 15.032 9.315 -10.764 1.00 47.88 H +ATOM 2818 HB VAL A 194 14.191 9.765 -8.486 1.00 48.42 H +ATOM 2819 HG11 VAL A 194 12.988 7.675 -8.078 1.00 48.70 H +ATOM 2820 HG12 VAL A 194 13.096 7.988 -9.801 1.00 48.70 H +ATOM 2821 HG13 VAL A 194 14.133 6.777 -9.049 1.00 48.70 H +ATOM 2822 HG21 VAL A 194 14.826 8.324 -6.533 1.00 48.70 H +ATOM 2823 HG22 VAL A 194 16.195 7.727 -7.446 1.00 48.70 H +ATOM 2824 HG23 VAL A 194 16.091 9.432 -7.015 1.00 48.70 H +ATOM 2825 N ILE A 195 16.084 11.468 -9.901 1.00 44.00 N +ATOM 2826 CA ILE A 195 16.733 12.741 -9.594 1.00 42.15 C +ATOM 2827 C ILE A 195 16.114 13.287 -8.303 1.00 39.98 C +ATOM 2828 O ILE A 195 14.891 13.378 -8.232 1.00 40.39 O +ATOM 2829 CB ILE A 195 16.504 13.768 -10.746 1.00 42.60 C +ATOM 2830 CG1 ILE A 195 17.329 13.348 -11.983 1.00 44.09 C +ATOM 2831 CG2 ILE A 195 16.803 15.243 -10.378 1.00 43.47 C +ATOM 2832 CD1 ILE A 195 16.950 14.086 -13.272 1.00 45.10 C +ATOM 2833 H ILE A 195 15.130 11.535 -10.231 1.00 44.00 H +ATOM 2834 HA ILE A 195 17.807 12.603 -9.450 1.00 42.15 H +ATOM 2835 HB ILE A 195 15.450 13.718 -11.028 1.00 42.60 H +ATOM 2836 HG13 ILE A 195 17.219 12.279 -12.164 1.00 44.09 H +ATOM 2837 HG12 ILE A 195 18.390 13.501 -11.781 1.00 44.09 H +ATOM 2838 HG21 ILE A 195 16.663 15.907 -11.231 1.00 43.47 H +ATOM 2839 HG22 ILE A 195 16.142 15.624 -9.599 1.00 43.47 H +ATOM 2840 HG23 ILE A 195 17.831 15.362 -10.034 1.00 43.47 H +ATOM 2841 HD11 ILE A 195 17.393 13.586 -14.133 1.00 45.10 H +ATOM 2842 HD12 ILE A 195 15.869 14.112 -13.415 1.00 45.10 H +ATOM 2843 HD13 ILE A 195 17.320 15.111 -13.274 1.00 45.10 H +ATOM 2844 N ILE A 196 16.960 13.663 -7.333 1.00 39.35 N +ATOM 2845 CA ILE A 196 16.533 14.278 -6.076 1.00 38.26 C +ATOM 2846 C ILE A 196 17.091 15.711 -6.063 1.00 39.38 C +ATOM 2847 O ILE A 196 18.280 15.916 -5.810 1.00 41.32 O +ATOM 2848 CB ILE A 196 17.032 13.494 -4.827 1.00 37.13 C +ATOM 2849 CG1 ILE A 196 16.555 12.020 -4.838 1.00 37.59 C +ATOM 2850 CG2 ILE A 196 16.604 14.156 -3.495 1.00 36.34 C +ATOM 2851 CD1 ILE A 196 17.502 11.069 -4.096 1.00 38.64 C +ATOM 2852 H ILE A 196 17.957 13.568 -7.465 1.00 39.35 H +ATOM 2853 HA ILE A 196 15.445 14.330 -6.013 1.00 38.26 H +ATOM 2854 HB ILE A 196 18.123 13.484 -4.855 1.00 37.13 H +ATOM 2855 HG13 ILE A 196 16.473 11.644 -5.856 1.00 37.59 H +ATOM 2856 HG12 ILE A 196 15.547 11.943 -4.428 1.00 37.59 H +ATOM 2857 HG21 ILE A 196 17.029 13.633 -2.639 1.00 36.34 H +ATOM 2858 HG22 ILE A 196 16.914 15.197 -3.420 1.00 36.34 H +ATOM 2859 HG23 ILE A 196 15.519 14.141 -3.383 1.00 36.34 H +ATOM 2860 HD11 ILE A 196 16.967 10.192 -3.730 1.00 38.64 H +ATOM 2861 HD12 ILE A 196 18.293 10.717 -4.759 1.00 38.64 H +ATOM 2862 HD13 ILE A 196 17.981 11.552 -3.245 1.00 38.64 H +ATOM 2863 N LYS A 197 16.206 16.669 -6.375 1.00 38.14 N +ATOM 2864 CA LYS A 197 16.483 18.101 -6.405 1.00 37.79 C +ATOM 2865 C LYS A 197 16.796 18.642 -5.000 1.00 36.85 C +ATOM 2866 O LYS A 197 15.981 18.483 -4.091 1.00 35.36 O +ATOM 2867 CB LYS A 197 15.276 18.827 -7.042 1.00 37.13 C +ATOM 2868 CG LYS A 197 15.433 20.356 -7.147 1.00 39.41 C +ATOM 2869 CD LYS A 197 14.198 21.047 -7.739 1.00 41.69 C +ATOM 2870 CE LYS A 197 14.383 22.571 -7.820 1.00 44.71 C +ATOM 2871 NZ LYS A 197 13.187 23.240 -8.360 1.00 46.18 N1+ +ATOM 2872 H LYS A 197 15.243 16.408 -6.536 1.00 38.14 H +ATOM 2873 HA LYS A 197 17.350 18.254 -7.051 1.00 37.79 H +ATOM 2874 HB3 LYS A 197 14.377 18.605 -6.466 1.00 37.13 H +ATOM 2875 HB2 LYS A 197 15.103 18.421 -8.040 1.00 37.13 H +ATOM 2876 HG3 LYS A 197 16.309 20.586 -7.755 1.00 39.41 H +ATOM 2877 HG2 LYS A 197 15.622 20.788 -6.164 1.00 39.41 H +ATOM 2878 HD3 LYS A 197 13.326 20.807 -7.128 1.00 41.69 H +ATOM 2879 HD2 LYS A 197 13.999 20.639 -8.732 1.00 41.69 H +ATOM 2880 HE3 LYS A 197 15.236 22.815 -8.455 1.00 44.71 H +ATOM 2881 HE2 LYS A 197 14.591 22.979 -6.831 1.00 44.71 H +ATOM 2882 HZ1 LYS A 197 12.394 23.046 -7.765 1.00 46.18 H +ATOM 2883 HZ2 LYS A 197 13.344 24.237 -8.397 1.00 46.18 H +ATOM 2884 HZ3 LYS A 197 12.998 22.895 -9.291 1.00 46.18 H +ATOM 2885 N GLY A 198 17.950 19.316 -4.887 1.00 38.11 N +ATOM 2886 CA GLY A 198 18.369 20.028 -3.683 1.00 39.85 C +ATOM 2887 C GLY A 198 19.177 19.157 -2.710 1.00 40.71 C +ATOM 2888 O GLY A 198 19.602 19.689 -1.687 1.00 41.56 O +ATOM 2889 H GLY A 198 18.561 19.387 -5.688 1.00 38.11 H +ATOM 2890 HA3 GLY A 198 17.508 20.447 -3.159 1.00 39.85 H +ATOM 2891 HA2 GLY A 198 18.990 20.872 -3.984 1.00 39.85 H +ATOM 2892 N LEU A 199 19.406 17.860 -3.002 1.00 40.46 N +ATOM 2893 CA LEU A 199 20.236 16.974 -2.181 1.00 40.03 C +ATOM 2894 C LEU A 199 21.720 17.357 -2.291 1.00 41.70 C +ATOM 2895 O LEU A 199 22.331 17.127 -3.336 1.00 41.24 O +ATOM 2896 CB LEU A 199 19.980 15.500 -2.569 1.00 37.82 C +ATOM 2897 CG LEU A 199 20.751 14.454 -1.727 1.00 36.34 C +ATOM 2898 CD1 LEU A 199 20.402 14.545 -0.229 1.00 35.93 C +ATOM 2899 CD2 LEU A 199 20.538 13.032 -2.280 1.00 35.17 C +ATOM 2900 H LEU A 199 19.042 17.467 -3.858 1.00 40.46 H +ATOM 2901 HA LEU A 199 19.922 17.100 -1.144 1.00 40.03 H +ATOM 2902 HB3 LEU A 199 20.215 15.363 -3.626 1.00 37.82 H +ATOM 2903 HB2 LEU A 199 18.917 15.298 -2.467 1.00 37.82 H +ATOM 2904 HG LEU A 199 21.819 14.653 -1.826 1.00 36.34 H +ATOM 2905 HD11 LEU A 199 20.575 13.602 0.290 1.00 35.93 H +ATOM 2906 HD12 LEU A 199 21.018 15.297 0.260 1.00 35.93 H +ATOM 2907 HD13 LEU A 199 19.361 14.826 -0.071 1.00 35.93 H +ATOM 2908 HD21 LEU A 199 21.481 12.487 -2.325 1.00 35.17 H +ATOM 2909 HD22 LEU A 199 19.850 12.452 -1.670 1.00 35.17 H +ATOM 2910 HD23 LEU A 199 20.127 13.046 -3.290 1.00 35.17 H +ATOM 2911 N GLU A 200 22.260 17.926 -1.202 1.00 42.28 N +ATOM 2912 CA GLU A 200 23.662 18.300 -1.065 1.00 45.64 C +ATOM 2913 C GLU A 200 24.586 17.084 -1.041 1.00 45.00 C +ATOM 2914 O GLU A 200 24.344 16.134 -0.298 1.00 43.55 O +ATOM 2915 CB GLU A 200 23.881 19.147 0.208 1.00 49.57 C +ATOM 2916 CG GLU A 200 23.403 20.605 0.081 1.00 57.01 C +ATOM 2917 CD GLU A 200 24.177 21.431 -0.956 1.00 60.33 C +ATOM 2918 OE1 GLU A 200 25.428 21.389 -0.918 1.00 62.11 O +ATOM 2919 OE2 GLU A 200 23.506 22.099 -1.773 1.00 62.56 O1- +ATOM 2920 H GLU A 200 21.673 18.114 -0.396 1.00 42.28 H +ATOM 2921 HA GLU A 200 23.922 18.895 -1.943 1.00 45.64 H +ATOM 2922 HB3 GLU A 200 24.932 19.133 0.505 1.00 49.57 H +ATOM 2923 HB2 GLU A 200 23.357 18.684 1.045 1.00 49.57 H +ATOM 2924 HG3 GLU A 200 23.558 21.094 1.039 1.00 57.01 H +ATOM 2925 HG2 GLU A 200 22.331 20.635 -0.120 1.00 57.01 H +ATOM 2926 N GLU A 201 25.655 17.189 -1.835 1.00 45.79 N +ATOM 2927 CA GLU A 201 26.770 16.261 -1.858 1.00 46.72 C +ATOM 2928 C GLU A 201 27.987 17.028 -1.341 1.00 46.76 C +ATOM 2929 O GLU A 201 28.514 17.885 -2.050 1.00 47.10 O +ATOM 2930 CB GLU A 201 26.981 15.751 -3.293 1.00 48.30 C +ATOM 2931 CG GLU A 201 25.827 14.857 -3.797 1.00 53.27 C +ATOM 2932 CD GLU A 201 26.003 14.333 -5.231 1.00 56.17 C +ATOM 2933 OE1 GLU A 201 25.324 13.334 -5.553 1.00 57.27 O +ATOM 2934 OE2 GLU A 201 26.803 14.919 -5.994 1.00 58.06 O1- +ATOM 2935 H GLU A 201 25.767 18.019 -2.401 1.00 45.79 H +ATOM 2936 HA GLU A 201 26.586 15.402 -1.213 1.00 46.72 H +ATOM 2937 HB3 GLU A 201 27.913 15.188 -3.337 1.00 48.30 H +ATOM 2938 HB2 GLU A 201 27.107 16.605 -3.962 1.00 48.30 H +ATOM 2939 HG3 GLU A 201 24.884 15.404 -3.759 1.00 53.27 H +ATOM 2940 HG2 GLU A 201 25.715 14.006 -3.124 1.00 53.27 H +ATOM 2941 N ILE A 202 28.387 16.724 -0.098 1.00 46.40 N +ATOM 2942 CA ILE A 202 29.537 17.339 0.553 1.00 46.13 C +ATOM 2943 C ILE A 202 30.800 16.547 0.202 1.00 45.18 C +ATOM 2944 O ILE A 202 30.892 15.369 0.548 1.00 45.33 O +ATOM 2945 CB ILE A 202 29.374 17.399 2.100 1.00 45.98 C +ATOM 2946 CG1 ILE A 202 28.192 18.330 2.456 1.00 47.32 C +ATOM 2947 CG2 ILE A 202 30.658 17.856 2.835 1.00 45.32 C +ATOM 2948 CD1 ILE A 202 27.916 18.466 3.957 1.00 48.95 C +ATOM 2949 H ILE A 202 27.912 15.995 0.419 1.00 46.40 H +ATOM 2950 HA ILE A 202 29.652 18.364 0.192 1.00 46.13 H +ATOM 2951 HB ILE A 202 29.126 16.398 2.460 1.00 45.98 H +ATOM 2952 HG13 ILE A 202 27.279 17.981 1.970 1.00 47.32 H +ATOM 2953 HG12 ILE A 202 28.382 19.324 2.049 1.00 47.32 H +ATOM 2954 HG21 ILE A 202 30.512 17.895 3.913 1.00 45.32 H +ATOM 2955 HG22 ILE A 202 31.500 17.184 2.676 1.00 45.32 H +ATOM 2956 HG23 ILE A 202 30.965 18.850 2.509 1.00 45.32 H +ATOM 2957 HD11 ILE A 202 26.907 18.840 4.115 1.00 48.95 H +ATOM 2958 HD12 ILE A 202 28.011 17.511 4.474 1.00 48.95 H +ATOM 2959 HD13 ILE A 202 28.597 19.176 4.426 1.00 48.95 H +ATOM 2960 N THR A 203 31.755 17.231 -0.447 1.00 44.53 N +ATOM 2961 CA THR A 203 33.084 16.702 -0.726 1.00 44.04 C +ATOM 2962 C THR A 203 33.895 16.557 0.574 1.00 43.54 C +ATOM 2963 O THR A 203 34.031 17.525 1.323 1.00 43.23 O +ATOM 2964 CB THR A 203 33.879 17.615 -1.695 1.00 44.86 C +ATOM 2965 OG1 THR A 203 33.165 17.718 -2.911 1.00 43.73 O +ATOM 2966 CG2 THR A 203 35.301 17.121 -2.028 1.00 44.45 C +ATOM 2967 H THR A 203 31.594 18.191 -0.714 1.00 44.53 H +ATOM 2968 HA THR A 203 32.958 15.728 -1.197 1.00 44.04 H +ATOM 2969 HB THR A 203 33.948 18.621 -1.278 1.00 44.86 H +ATOM 2970 HG1 THR A 203 33.191 16.868 -3.355 1.00 43.73 H +ATOM 2971 HG21 THR A 203 35.766 17.749 -2.788 1.00 44.45 H +ATOM 2972 HG22 THR A 203 35.957 17.141 -1.157 1.00 44.45 H +ATOM 2973 HG23 THR A 203 35.287 16.098 -2.407 1.00 44.45 H +ATOM 2974 N VAL A 204 34.418 15.345 0.788 1.00 44.30 N +ATOM 2975 CA VAL A 204 35.281 14.998 1.904 1.00 45.77 C +ATOM 2976 C VAL A 204 36.712 14.913 1.337 1.00 46.96 C +ATOM 2977 O VAL A 204 36.987 14.072 0.480 1.00 47.51 O +ATOM 2978 CB VAL A 204 34.901 13.628 2.533 1.00 44.79 C +ATOM 2979 CG1 VAL A 204 35.601 13.429 3.888 1.00 45.00 C +ATOM 2980 CG2 VAL A 204 33.382 13.431 2.688 1.00 44.50 C +ATOM 2981 H VAL A 204 34.268 14.612 0.105 1.00 44.30 H +ATOM 2982 HA VAL A 204 35.229 15.762 2.681 1.00 45.77 H +ATOM 2983 HB VAL A 204 35.224 12.820 1.880 1.00 44.79 H +ATOM 2984 HG11 VAL A 204 35.324 12.471 4.321 1.00 45.00 H +ATOM 2985 HG12 VAL A 204 36.685 13.444 3.790 1.00 45.00 H +ATOM 2986 HG13 VAL A 204 35.324 14.207 4.601 1.00 45.00 H +ATOM 2987 HG21 VAL A 204 33.152 12.516 3.236 1.00 44.50 H +ATOM 2988 HG22 VAL A 204 32.926 14.261 3.218 1.00 44.50 H +ATOM 2989 HG23 VAL A 204 32.889 13.352 1.719 1.00 44.50 H +ATOM 2990 N HIS A 205 37.575 15.836 1.781 1.00 48.27 N +ATOM 2991 CA HIS A 205 38.931 16.026 1.262 1.00 50.42 C +ATOM 2992 C HIS A 205 39.951 15.083 1.921 1.00 50.78 C +ATOM 2993 O HIS A 205 40.913 14.695 1.260 1.00 50.81 O +ATOM 2994 CB HIS A 205 39.346 17.499 1.461 1.00 50.66 C +ATOM 2995 CG HIS A 205 38.441 18.496 0.772 1.00 50.85 C +ATOM 2996 ND1 HIS A 205 37.443 19.173 1.453 1.00 51.12 N1+ +ATOM 2997 CD2 HIS A 205 38.419 18.960 -0.530 1.00 50.79 C +ATOM 2998 CE1 HIS A 205 36.831 19.966 0.580 1.00 50.20 C +ATOM 2999 NE2 HIS A 205 37.383 19.876 -0.628 1.00 50.46 N +ATOM 3000 H HIS A 205 37.269 16.496 2.488 1.00 48.27 H +ATOM 3001 HA HIS A 205 38.931 15.817 0.190 1.00 50.42 H +ATOM 3002 HB3 HIS A 205 40.355 17.653 1.078 1.00 50.66 H +ATOM 3003 HB2 HIS A 205 39.386 17.740 2.524 1.00 50.66 H +ATOM 3004 HD1 HIS A 205 37.198 19.056 2.434 1.00 51.12 H +ATOM 3005 HD2 HIS A 205 39.029 18.715 -1.387 1.00 50.79 H +ATOM 3006 HE1 HIS A 205 35.993 20.603 0.824 1.00 50.20 H +ATOM 3007 HE2 HIS A 205 37.102 20.383 -1.456 1.00 50.46 H +ATOM 3008 N ASN A 206 39.723 14.732 3.196 1.00 51.18 N +ATOM 3009 CA ASN A 206 40.587 13.867 4.002 1.00 51.18 C +ATOM 3010 C ASN A 206 39.800 13.298 5.192 1.00 51.21 C +ATOM 3011 O ASN A 206 38.724 13.802 5.521 1.00 51.46 O +ATOM 3012 CB ASN A 206 41.888 14.608 4.425 1.00 50.68 C +ATOM 3013 CG ASN A 206 41.676 15.927 5.184 1.00 52.37 C +ATOM 3014 OD1 ASN A 206 41.149 15.935 6.292 1.00 53.55 O +ATOM 3015 ND2 ASN A 206 42.102 17.048 4.600 1.00 52.82 N +ATOM 3016 H ASN A 206 38.896 15.074 3.667 1.00 51.18 H +ATOM 3017 HA ASN A 206 40.870 13.027 3.366 1.00 51.18 H +ATOM 3018 HB3 ASN A 206 42.489 14.809 3.538 1.00 50.68 H +ATOM 3019 HB2 ASN A 206 42.503 13.956 5.047 1.00 50.68 H +ATOM 3020 HD22 ASN A 206 41.990 17.933 5.072 1.00 52.82 H +ATOM 3021 HD21 ASN A 206 42.546 17.020 3.693 1.00 52.82 H +ATOM 3022 N LYS A 207 40.377 12.268 5.835 1.00 52.18 N +ATOM 3023 CA LYS A 207 39.844 11.647 7.051 1.00 53.37 C +ATOM 3024 C LYS A 207 39.692 12.620 8.237 1.00 53.82 C +ATOM 3025 O LYS A 207 38.712 12.501 8.964 1.00 53.82 O +ATOM 3026 CB LYS A 207 40.661 10.397 7.432 1.00 55.31 C +ATOM 3027 CG LYS A 207 42.174 10.642 7.607 1.00 56.90 C +ATOM 3028 CD LYS A 207 42.791 9.989 8.851 1.00 58.37 C +ATOM 3029 CE LYS A 207 42.207 10.523 10.171 1.00 58.94 C +ATOM 3030 NZ LYS A 207 43.150 10.352 11.287 1.00 60.33 N1+ +ATOM 3031 H LYS A 207 41.258 11.904 5.502 1.00 52.18 H +ATOM 3032 HA LYS A 207 38.849 11.290 6.798 1.00 53.37 H +ATOM 3033 HB3 LYS A 207 40.517 9.625 6.679 1.00 55.31 H +ATOM 3034 HB2 LYS A 207 40.234 9.970 8.340 1.00 55.31 H +ATOM 3035 HG3 LYS A 207 42.401 11.707 7.630 1.00 56.90 H +ATOM 3036 HG2 LYS A 207 42.690 10.265 6.723 1.00 56.90 H +ATOM 3037 HD3 LYS A 207 43.870 10.153 8.813 1.00 58.37 H +ATOM 3038 HD2 LYS A 207 42.651 8.907 8.799 1.00 58.37 H +ATOM 3039 HE3 LYS A 207 41.268 10.025 10.414 1.00 58.94 H +ATOM 3040 HE2 LYS A 207 41.982 11.584 10.088 1.00 58.94 H +ATOM 3041 HZ1 LYS A 207 43.986 10.889 11.103 1.00 60.33 H +ATOM 3042 HZ2 LYS A 207 42.716 10.697 12.135 1.00 60.33 H +ATOM 3043 HZ3 LYS A 207 43.382 9.375 11.397 1.00 60.33 H +ATOM 3044 N ASP A 208 40.598 13.605 8.367 1.00 53.64 N +ATOM 3045 CA ASP A 208 40.578 14.669 9.385 1.00 54.33 C +ATOM 3046 C ASP A 208 39.460 15.724 9.194 1.00 53.71 C +ATOM 3047 O ASP A 208 39.445 16.713 9.926 1.00 54.95 O +ATOM 3048 CB ASP A 208 41.962 15.346 9.585 1.00 56.35 C +ATOM 3049 CG ASP A 208 43.135 14.361 9.717 1.00 58.62 C +ATOM 3050 OD1 ASP A 208 43.298 13.818 10.832 1.00 59.21 O +ATOM 3051 OD2 ASP A 208 43.750 14.043 8.674 1.00 60.63 O1- +ATOM 3052 H ASP A 208 41.367 13.656 7.713 1.00 53.64 H +ATOM 3053 HA ASP A 208 40.341 14.177 10.331 1.00 54.33 H +ATOM 3054 HB3 ASP A 208 41.945 15.959 10.488 1.00 56.35 H +ATOM 3055 HB2 ASP A 208 42.172 16.024 8.757 1.00 56.35 H +ATOM 3056 N GLU A 209 38.540 15.490 8.244 1.00 52.25 N +ATOM 3057 CA GLU A 209 37.350 16.296 7.978 1.00 50.66 C +ATOM 3058 C GLU A 209 36.059 15.451 8.073 1.00 48.60 C +ATOM 3059 O GLU A 209 34.976 16.033 8.133 1.00 47.52 O +ATOM 3060 CB GLU A 209 37.525 16.928 6.584 1.00 52.62 C +ATOM 3061 CG GLU A 209 36.485 18.011 6.222 1.00 55.80 C +ATOM 3062 CD GLU A 209 36.679 18.541 4.802 1.00 58.39 C +ATOM 3063 OE1 GLU A 209 36.692 17.701 3.880 1.00 60.18 O +ATOM 3064 OE2 GLU A 209 36.806 19.774 4.639 1.00 60.45 O1- +ATOM 3065 H GLU A 209 38.660 14.682 7.649 1.00 52.25 H +ATOM 3066 HA GLU A 209 37.265 17.096 8.715 1.00 50.66 H +ATOM 3067 HB3 GLU A 209 37.498 16.128 5.842 1.00 52.62 H +ATOM 3068 HB2 GLU A 209 38.523 17.363 6.509 1.00 52.62 H +ATOM 3069 HG3 GLU A 209 36.537 18.827 6.945 1.00 55.80 H +ATOM 3070 HG2 GLU A 209 35.470 17.620 6.273 1.00 55.80 H +ATOM 3071 N VAL A 210 36.179 14.107 8.111 1.00 46.40 N +ATOM 3072 CA VAL A 210 35.064 13.157 8.216 1.00 44.14 C +ATOM 3073 C VAL A 210 34.184 13.402 9.451 1.00 43.51 C +ATOM 3074 O VAL A 210 32.966 13.475 9.303 1.00 42.39 O +ATOM 3075 CB VAL A 210 35.563 11.677 8.236 1.00 44.48 C +ATOM 3076 CG1 VAL A 210 34.548 10.607 8.703 1.00 42.85 C +ATOM 3077 CG2 VAL A 210 36.103 11.282 6.855 1.00 42.99 C +ATOM 3078 H VAL A 210 37.100 13.694 8.085 1.00 46.40 H +ATOM 3079 HA VAL A 210 34.438 13.300 7.333 1.00 44.14 H +ATOM 3080 HB VAL A 210 36.393 11.620 8.937 1.00 44.48 H +ATOM 3081 HG11 VAL A 210 34.965 9.606 8.597 1.00 42.85 H +ATOM 3082 HG12 VAL A 210 34.286 10.715 9.756 1.00 42.85 H +ATOM 3083 HG13 VAL A 210 33.629 10.648 8.118 1.00 42.85 H +ATOM 3084 HG21 VAL A 210 36.648 10.339 6.899 1.00 42.99 H +ATOM 3085 HG22 VAL A 210 35.287 11.165 6.144 1.00 42.99 H +ATOM 3086 HG23 VAL A 210 36.777 12.038 6.453 1.00 42.99 H +ATOM 3087 N TYR A 211 34.816 13.545 10.629 1.00 42.45 N +ATOM 3088 CA TYR A 211 34.116 13.676 11.904 1.00 41.99 C +ATOM 3089 C TYR A 211 33.244 14.937 12.017 1.00 43.14 C +ATOM 3090 O TYR A 211 32.134 14.827 12.533 1.00 42.53 O +ATOM 3091 CB TYR A 211 35.115 13.564 13.065 1.00 40.52 C +ATOM 3092 CG TYR A 211 34.451 13.378 14.414 1.00 39.40 C +ATOM 3093 CD1 TYR A 211 33.783 12.168 14.683 1.00 39.03 C +ATOM 3094 CD2 TYR A 211 34.452 14.409 15.376 1.00 39.70 C +ATOM 3095 CE1 TYR A 211 33.083 12.003 15.887 1.00 37.82 C +ATOM 3096 CE2 TYR A 211 33.743 14.243 16.582 1.00 39.48 C +ATOM 3097 CZ TYR A 211 33.032 13.052 16.824 1.00 38.29 C +ATOM 3098 OH TYR A 211 32.279 12.914 17.953 1.00 39.27 O +ATOM 3099 H TYR A 211 35.824 13.494 10.668 1.00 42.45 H +ATOM 3100 HA TYR A 211 33.441 12.820 11.965 1.00 41.99 H +ATOM 3101 HB3 TYR A 211 35.794 14.418 13.086 1.00 40.52 H +ATOM 3102 HB2 TYR A 211 35.730 12.685 12.894 1.00 40.52 H +ATOM 3103 HD1 TYR A 211 33.791 11.368 13.957 1.00 39.03 H +ATOM 3104 HD2 TYR A 211 34.960 15.341 15.179 1.00 39.70 H +ATOM 3105 HE1 TYR A 211 32.574 11.072 16.069 1.00 37.82 H +ATOM 3106 HE2 TYR A 211 33.720 15.047 17.304 1.00 39.48 H +ATOM 3107 HH TYR A 211 32.066 13.751 18.382 1.00 39.27 H +ATOM 3108 N GLN A 212 33.723 16.076 11.484 1.00 43.75 N +ATOM 3109 CA GLN A 212 32.967 17.331 11.390 1.00 43.56 C +ATOM 3110 C GLN A 212 31.652 17.219 10.604 1.00 41.95 C +ATOM 3111 O GLN A 212 30.649 17.793 11.026 1.00 41.64 O +ATOM 3112 CB GLN A 212 33.842 18.445 10.781 1.00 46.00 C +ATOM 3113 CG GLN A 212 34.710 19.183 11.809 1.00 48.97 C +ATOM 3114 CD GLN A 212 35.341 20.426 11.181 1.00 50.63 C +ATOM 3115 OE1 GLN A 212 36.243 20.316 10.355 1.00 50.62 O +ATOM 3116 NE2 GLN A 212 34.862 21.612 11.560 1.00 51.22 N +ATOM 3117 H GLN A 212 34.640 16.078 11.061 1.00 43.75 H +ATOM 3118 HA GLN A 212 32.696 17.617 12.407 1.00 43.56 H +ATOM 3119 HB3 GLN A 212 33.199 19.188 10.303 1.00 46.00 H +ATOM 3120 HB2 GLN A 212 34.464 18.044 9.979 1.00 46.00 H +ATOM 3121 HG3 GLN A 212 35.495 18.526 12.185 1.00 48.97 H +ATOM 3122 HG2 GLN A 212 34.109 19.478 12.671 1.00 48.97 H +ATOM 3123 HE22 GLN A 212 35.249 22.458 11.168 1.00 51.22 H +ATOM 3124 HE21 GLN A 212 34.119 21.673 12.241 1.00 51.22 H +ATOM 3125 N ILE A 213 31.687 16.476 9.487 1.00 40.96 N +ATOM 3126 CA ILE A 213 30.529 16.230 8.629 1.00 40.40 C +ATOM 3127 C ILE A 213 29.480 15.340 9.326 1.00 38.82 C +ATOM 3128 O ILE A 213 28.289 15.636 9.231 1.00 38.70 O +ATOM 3129 CB ILE A 213 30.957 15.608 7.268 1.00 41.38 C +ATOM 3130 CG1 ILE A 213 31.837 16.609 6.480 1.00 41.39 C +ATOM 3131 CG2 ILE A 213 29.782 15.120 6.391 1.00 41.81 C +ATOM 3132 CD1 ILE A 213 32.608 15.980 5.316 1.00 43.68 C +ATOM 3133 H ILE A 213 32.552 16.034 9.207 1.00 40.96 H +ATOM 3134 HA ILE A 213 30.056 17.193 8.425 1.00 40.40 H +ATOM 3135 HB ILE A 213 31.577 14.737 7.480 1.00 41.38 H +ATOM 3136 HG13 ILE A 213 32.570 17.079 7.135 1.00 41.39 H +ATOM 3137 HG12 ILE A 213 31.216 17.426 6.109 1.00 41.39 H +ATOM 3138 HG21 ILE A 213 30.126 14.797 5.412 1.00 41.81 H +ATOM 3139 HG22 ILE A 213 29.266 14.267 6.831 1.00 41.81 H +ATOM 3140 HG23 ILE A 213 29.053 15.914 6.230 1.00 41.81 H +ATOM 3141 HD11 ILE A 213 33.407 16.639 4.973 1.00 43.68 H +ATOM 3142 HD12 ILE A 213 33.065 15.033 5.605 1.00 43.68 H +ATOM 3143 HD13 ILE A 213 31.949 15.797 4.470 1.00 43.68 H +ATOM 3144 N LEU A 214 29.945 14.313 10.058 1.00 37.14 N +ATOM 3145 CA LEU A 214 29.104 13.416 10.852 1.00 36.39 C +ATOM 3146 C LEU A 214 28.479 14.105 12.081 1.00 36.96 C +ATOM 3147 O LEU A 214 27.314 13.834 12.371 1.00 36.52 O +ATOM 3148 CB LEU A 214 29.912 12.164 11.257 1.00 34.22 C +ATOM 3149 CG LEU A 214 30.410 11.292 10.082 1.00 34.05 C +ATOM 3150 CD1 LEU A 214 31.178 10.063 10.600 1.00 33.97 C +ATOM 3151 CD2 LEU A 214 29.303 10.894 9.091 1.00 31.89 C +ATOM 3152 H LEU A 214 30.941 14.140 10.094 1.00 37.14 H +ATOM 3153 HA LEU A 214 28.269 13.107 10.222 1.00 36.39 H +ATOM 3154 HB3 LEU A 214 29.294 11.542 11.899 1.00 34.22 H +ATOM 3155 HB2 LEU A 214 30.763 12.466 11.870 1.00 34.22 H +ATOM 3156 HG LEU A 214 31.126 11.880 9.516 1.00 34.05 H +ATOM 3157 HD11 LEU A 214 31.949 9.759 9.893 1.00 33.97 H +ATOM 3158 HD12 LEU A 214 31.673 10.271 11.547 1.00 33.97 H +ATOM 3159 HD13 LEU A 214 30.517 9.209 10.755 1.00 33.97 H +ATOM 3160 HD21 LEU A 214 29.456 9.893 8.693 1.00 31.89 H +ATOM 3161 HD22 LEU A 214 28.316 10.916 9.549 1.00 31.89 H +ATOM 3162 HD23 LEU A 214 29.286 11.573 8.238 1.00 31.89 H +ATOM 3163 N GLU A 215 29.221 15.016 12.741 1.00 36.83 N +ATOM 3164 CA GLU A 215 28.717 15.886 13.811 1.00 37.19 C +ATOM 3165 C GLU A 215 27.581 16.810 13.352 1.00 35.62 C +ATOM 3166 O GLU A 215 26.598 16.939 14.080 1.00 34.59 O +ATOM 3167 CB GLU A 215 29.846 16.745 14.410 1.00 38.50 C +ATOM 3168 CG GLU A 215 30.763 16.002 15.394 1.00 40.59 C +ATOM 3169 CD GLU A 215 31.796 16.959 16.002 1.00 43.18 C +ATOM 3170 OE1 GLU A 215 32.668 17.433 15.241 1.00 43.05 O +ATOM 3171 OE2 GLU A 215 31.698 17.203 17.225 1.00 42.79 O1- +ATOM 3172 H GLU A 215 30.184 15.164 12.467 1.00 36.83 H +ATOM 3173 HA GLU A 215 28.313 15.245 14.597 1.00 37.19 H +ATOM 3174 HB3 GLU A 215 29.426 17.616 14.918 1.00 38.50 H +ATOM 3175 HB2 GLU A 215 30.451 17.147 13.597 1.00 38.50 H +ATOM 3176 HG3 GLU A 215 31.280 15.179 14.902 1.00 40.59 H +ATOM 3177 HG2 GLU A 215 30.163 15.548 16.184 1.00 40.59 H +ATOM 3178 N LYS A 216 27.722 17.402 12.152 1.00 34.60 N +ATOM 3179 CA LYS A 216 26.673 18.182 11.491 1.00 35.20 C +ATOM 3180 C LYS A 216 25.416 17.356 11.182 1.00 33.65 C +ATOM 3181 O LYS A 216 24.317 17.870 11.373 1.00 33.67 O +ATOM 3182 CB LYS A 216 27.231 18.877 10.226 1.00 37.19 C +ATOM 3183 CG LYS A 216 27.593 20.356 10.444 1.00 41.61 C +ATOM 3184 CD LYS A 216 26.351 21.265 10.575 1.00 45.71 C +ATOM 3185 CE LYS A 216 26.675 22.749 10.822 1.00 48.01 C +ATOM 3186 NZ LYS A 216 27.247 22.987 12.161 1.00 49.53 N1+ +ATOM 3187 H LYS A 216 28.573 17.260 11.625 1.00 34.60 H +ATOM 3188 HA LYS A 216 26.375 18.944 12.212 1.00 35.20 H +ATOM 3189 HB3 LYS A 216 26.504 18.839 9.412 1.00 37.19 H +ATOM 3190 HB2 LYS A 216 28.097 18.331 9.849 1.00 37.19 H +ATOM 3191 HG3 LYS A 216 28.196 20.697 9.602 1.00 41.61 H +ATOM 3192 HG2 LYS A 216 28.229 20.439 11.325 1.00 41.61 H +ATOM 3193 HD3 LYS A 216 25.684 20.900 11.358 1.00 45.71 H +ATOM 3194 HD2 LYS A 216 25.772 21.194 9.652 1.00 45.71 H +ATOM 3195 HE3 LYS A 216 25.762 23.341 10.737 1.00 48.01 H +ATOM 3196 HE2 LYS A 216 27.363 23.120 10.062 1.00 48.01 H +ATOM 3197 HZ1 LYS A 216 28.109 22.470 12.256 1.00 49.53 H +ATOM 3198 HZ2 LYS A 216 27.434 23.973 12.278 1.00 49.53 H +ATOM 3199 HZ3 LYS A 216 26.594 22.683 12.868 1.00 49.53 H +ATOM 3200 N GLY A 217 25.605 16.088 10.778 1.00 33.75 N +ATOM 3201 CA GLY A 217 24.547 15.106 10.549 1.00 32.24 C +ATOM 3202 C GLY A 217 23.714 14.869 11.815 1.00 30.95 C +ATOM 3203 O GLY A 217 22.497 15.046 11.788 1.00 30.94 O +ATOM 3204 H GLY A 217 26.553 15.763 10.645 1.00 33.75 H +ATOM 3205 HA3 GLY A 217 25.004 14.166 10.240 1.00 32.24 H +ATOM 3206 HA2 GLY A 217 23.908 15.430 9.735 1.00 32.24 H +ATOM 3207 N ALA A 218 24.390 14.516 12.921 1.00 31.76 N +ATOM 3208 CA ALA A 218 23.798 14.267 14.237 1.00 30.06 C +ATOM 3209 C ALA A 218 23.133 15.502 14.875 1.00 30.68 C +ATOM 3210 O ALA A 218 22.100 15.352 15.529 1.00 28.25 O +ATOM 3211 CB ALA A 218 24.881 13.694 15.163 1.00 30.77 C +ATOM 3212 H ALA A 218 25.394 14.401 12.862 1.00 31.76 H +ATOM 3213 HA ALA A 218 23.026 13.507 14.110 1.00 30.06 H +ATOM 3214 HB1 ALA A 218 24.487 13.496 16.160 1.00 30.77 H +ATOM 3215 HB2 ALA A 218 25.266 12.752 14.774 1.00 30.77 H +ATOM 3216 HB3 ALA A 218 25.725 14.378 15.267 1.00 30.77 H +ATOM 3217 N ALA A 219 23.713 16.694 14.654 1.00 30.08 N +ATOM 3218 CA ALA A 219 23.179 17.977 15.111 1.00 31.41 C +ATOM 3219 C ALA A 219 21.873 18.360 14.401 1.00 31.60 C +ATOM 3220 O ALA A 219 20.940 18.801 15.070 1.00 31.54 O +ATOM 3221 CB ALA A 219 24.238 19.073 14.927 1.00 34.27 C +ATOM 3222 H ALA A 219 24.578 16.734 14.129 1.00 30.08 H +ATOM 3223 HA ALA A 219 22.967 17.890 16.178 1.00 31.41 H +ATOM 3224 HB1 ALA A 219 23.867 20.042 15.264 1.00 34.27 H +ATOM 3225 HB2 ALA A 219 25.135 18.850 15.505 1.00 34.27 H +ATOM 3226 HB3 ALA A 219 24.533 19.176 13.883 1.00 34.27 H +ATOM 3227 N LYS A 220 21.809 18.143 13.075 1.00 32.32 N +ATOM 3228 CA LYS A 220 20.595 18.345 12.285 1.00 32.64 C +ATOM 3229 C LYS A 220 19.482 17.338 12.624 1.00 30.46 C +ATOM 3230 O LYS A 220 18.320 17.736 12.611 1.00 31.31 O +ATOM 3231 CB LYS A 220 20.920 18.360 10.780 1.00 35.19 C +ATOM 3232 CG LYS A 220 21.672 19.626 10.319 1.00 41.44 C +ATOM 3233 CD LYS A 220 21.510 19.893 8.816 1.00 45.82 C +ATOM 3234 CE LYS A 220 20.213 20.659 8.510 1.00 46.78 C +ATOM 3235 NZ LYS A 220 19.777 20.499 7.115 1.00 49.70 N1+ +ATOM 3236 H LYS A 220 22.615 17.785 12.580 1.00 32.32 H +ATOM 3237 HA LYS A 220 20.203 19.330 12.545 1.00 32.64 H +ATOM 3238 HB3 LYS A 220 19.977 18.318 10.235 1.00 35.19 H +ATOM 3239 HB2 LYS A 220 21.471 17.464 10.492 1.00 35.19 H +ATOM 3240 HG3 LYS A 220 22.730 19.537 10.549 1.00 41.44 H +ATOM 3241 HG2 LYS A 220 21.329 20.497 10.878 1.00 41.44 H +ATOM 3242 HD3 LYS A 220 21.528 18.946 8.280 1.00 45.82 H +ATOM 3243 HD2 LYS A 220 22.371 20.456 8.456 1.00 45.82 H +ATOM 3244 HE3 LYS A 220 20.345 21.720 8.724 1.00 46.78 H +ATOM 3245 HE2 LYS A 220 19.409 20.315 9.148 1.00 46.78 H +ATOM 3246 HZ1 LYS A 220 20.506 20.849 6.506 1.00 49.70 H +ATOM 3247 HZ2 LYS A 220 19.595 19.527 6.900 1.00 49.70 H +ATOM 3248 HZ3 LYS A 220 18.939 21.039 6.955 1.00 49.70 H +ATOM 3249 N ARG A 221 19.833 16.090 12.988 1.00 29.75 N +ATOM 3250 CA ARG A 221 18.874 15.095 13.486 1.00 28.19 C +ATOM 3251 C ARG A 221 18.180 15.489 14.797 1.00 27.11 C +ATOM 3252 O ARG A 221 17.042 15.071 14.998 1.00 26.10 O +ATOM 3253 CB ARG A 221 19.540 13.730 13.697 1.00 30.31 C +ATOM 3254 CG ARG A 221 19.927 13.005 12.406 1.00 30.67 C +ATOM 3255 CD ARG A 221 19.353 11.585 12.409 1.00 34.41 C +ATOM 3256 NE ARG A 221 19.885 10.797 11.306 1.00 31.18 N +ATOM 3257 CZ ARG A 221 21.010 10.074 11.293 1.00 30.15 C +ATOM 3258 NH1 ARG A 221 21.803 9.984 12.368 1.00 26.01 N +ATOM 3259 NH2 ARG A 221 21.325 9.427 10.169 1.00 29.12 N1+ +ATOM 3260 H ARG A 221 20.805 15.811 12.963 1.00 29.75 H +ATOM 3261 HA ARG A 221 18.085 14.982 12.742 1.00 28.19 H +ATOM 3262 HB3 ARG A 221 18.846 13.096 14.253 1.00 30.31 H +ATOM 3263 HB2 ARG A 221 20.414 13.819 14.341 1.00 30.31 H +ATOM 3264 HG3 ARG A 221 21.000 13.015 12.220 1.00 30.67 H +ATOM 3265 HG2 ARG A 221 19.474 13.541 11.571 1.00 30.67 H +ATOM 3266 HD3 ARG A 221 18.287 11.652 12.185 1.00 34.41 H +ATOM 3267 HD2 ARG A 221 19.428 11.083 13.374 1.00 34.41 H +ATOM 3268 HE ARG A 221 19.373 10.871 10.431 1.00 31.18 H +ATOM 3269 HH12 ARG A 221 22.601 9.356 12.361 1.00 26.01 H +ATOM 3270 HH11 ARG A 221 21.562 10.468 13.219 1.00 26.01 H +ATOM 3271 HH22 ARG A 221 22.124 8.802 10.158 1.00 29.12 H +ATOM 3272 HH21 ARG A 221 20.746 9.532 9.345 1.00 29.12 H +ATOM 3273 N THR A 222 18.853 16.278 15.650 1.00 25.90 N +ATOM 3274 CA THR A 222 18.279 16.788 16.895 1.00 26.98 C +ATOM 3275 C THR A 222 17.165 17.823 16.633 1.00 24.38 C +ATOM 3276 O THR A 222 16.139 17.783 17.313 1.00 25.97 O +ATOM 3277 CB THR A 222 19.360 17.426 17.804 1.00 27.34 C +ATOM 3278 OG1 THR A 222 20.358 16.460 18.081 1.00 28.70 O +ATOM 3279 CG2 THR A 222 18.845 17.969 19.149 1.00 29.13 C +ATOM 3280 H THR A 222 19.787 16.585 15.420 1.00 25.90 H +ATOM 3281 HA THR A 222 17.835 15.947 17.433 1.00 26.98 H +ATOM 3282 HB THR A 222 19.845 18.247 17.278 1.00 27.34 H +ATOM 3283 HG1 THR A 222 20.778 16.198 17.257 1.00 28.70 H +ATOM 3284 HG21 THR A 222 19.672 18.309 19.774 1.00 29.13 H +ATOM 3285 HG22 THR A 222 18.177 18.821 19.018 1.00 29.13 H +ATOM 3286 HG23 THR A 222 18.304 17.202 19.703 1.00 29.13 H +ATOM 3287 N THR A 223 17.357 18.681 15.615 1.00 26.05 N +ATOM 3288 CA THR A 223 16.345 19.631 15.145 1.00 28.52 C +ATOM 3289 C THR A 223 15.186 18.937 14.394 1.00 27.17 C +ATOM 3290 O THR A 223 14.052 19.396 14.510 1.00 27.18 O +ATOM 3291 CB THR A 223 16.954 20.753 14.254 1.00 30.32 C +ATOM 3292 OG1 THR A 223 17.185 20.375 12.911 1.00 39.33 O +ATOM 3293 CG2 THR A 223 18.227 21.389 14.832 1.00 30.64 C +ATOM 3294 H THR A 223 18.222 18.652 15.094 1.00 26.05 H +ATOM 3295 HA THR A 223 15.915 20.115 16.024 1.00 28.52 H +ATOM 3296 HB THR A 223 16.208 21.548 14.198 1.00 30.32 H +ATOM 3297 HG1 THR A 223 17.773 19.613 12.896 1.00 39.33 H +ATOM 3298 HG21 THR A 223 18.547 22.240 14.229 1.00 30.64 H +ATOM 3299 HG22 THR A 223 18.057 21.750 15.847 1.00 30.64 H +ATOM 3300 HG23 THR A 223 19.055 20.682 14.863 1.00 30.64 H +ATOM 3301 N ALA A 224 15.468 17.821 13.696 1.00 25.91 N +ATOM 3302 CA ALA A 224 14.459 16.977 13.053 1.00 24.46 C +ATOM 3303 C ALA A 224 13.585 16.233 14.076 1.00 23.90 C +ATOM 3304 O ALA A 224 12.376 16.155 13.878 1.00 20.38 O +ATOM 3305 CB ALA A 224 15.144 15.998 12.089 1.00 24.41 C +ATOM 3306 H ALA A 224 16.426 17.505 13.626 1.00 25.91 H +ATOM 3307 HA ALA A 224 13.802 17.620 12.466 1.00 24.46 H +ATOM 3308 HB1 ALA A 224 14.407 15.437 11.516 1.00 24.41 H +ATOM 3309 HB2 ALA A 224 15.777 16.522 11.374 1.00 24.41 H +ATOM 3310 HB3 ALA A 224 15.764 15.276 12.618 1.00 24.41 H +ATOM 3311 N ALA A 225 14.198 15.758 15.174 1.00 24.13 N +ATOM 3312 CA ALA A 225 13.517 15.140 16.311 1.00 25.95 C +ATOM 3313 C ALA A 225 12.609 16.104 17.090 1.00 25.57 C +ATOM 3314 O ALA A 225 11.577 15.664 17.597 1.00 26.74 O +ATOM 3315 CB ALA A 225 14.558 14.488 17.233 1.00 23.02 C +ATOM 3316 H ALA A 225 15.204 15.839 15.252 1.00 24.13 H +ATOM 3317 HA ALA A 225 12.867 14.358 15.926 1.00 25.95 H +ATOM 3318 HB1 ALA A 225 14.085 14.009 18.091 1.00 23.02 H +ATOM 3319 HB2 ALA A 225 15.121 13.720 16.701 1.00 23.02 H +ATOM 3320 HB3 ALA A 225 15.273 15.218 17.614 1.00 23.02 H +ATOM 3321 N THR A 226 12.980 17.394 17.136 1.00 25.99 N +ATOM 3322 CA THR A 226 12.169 18.458 17.729 1.00 26.54 C +ATOM 3323 C THR A 226 10.896 18.746 16.904 1.00 25.91 C +ATOM 3324 O THR A 226 9.824 18.897 17.491 1.00 26.81 O +ATOM 3325 CB THR A 226 12.980 19.776 17.866 1.00 27.83 C +ATOM 3326 OG1 THR A 226 14.105 19.547 18.692 1.00 29.02 O +ATOM 3327 CG2 THR A 226 12.208 20.975 18.450 1.00 30.31 C +ATOM 3328 H THR A 226 13.843 17.678 16.696 1.00 25.99 H +ATOM 3329 HA THR A 226 11.861 18.136 18.726 1.00 26.54 H +ATOM 3330 HB THR A 226 13.365 20.071 16.891 1.00 27.83 H +ATOM 3331 HG1 THR A 226 14.675 18.896 18.271 1.00 29.02 H +ATOM 3332 HG21 THR A 226 12.874 21.822 18.620 1.00 30.31 H +ATOM 3333 HG22 THR A 226 11.422 21.321 17.778 1.00 30.31 H +ATOM 3334 HG23 THR A 226 11.747 20.720 19.404 1.00 30.31 H +ATOM 3335 N LEU A 227 11.039 18.796 15.569 1.00 26.53 N +ATOM 3336 CA LEU A 227 9.971 19.157 14.634 1.00 26.89 C +ATOM 3337 C LEU A 227 8.993 18.011 14.324 1.00 26.84 C +ATOM 3338 O LEU A 227 7.818 18.293 14.092 1.00 27.26 O +ATOM 3339 CB LEU A 227 10.609 19.683 13.327 1.00 28.85 C +ATOM 3340 CG LEU A 227 11.323 21.046 13.476 1.00 34.29 C +ATOM 3341 CD1 LEU A 227 12.190 21.352 12.239 1.00 36.73 C +ATOM 3342 CD2 LEU A 227 10.335 22.189 13.799 1.00 33.59 C +ATOM 3343 H LEU A 227 11.951 18.646 15.160 1.00 26.53 H +ATOM 3344 HA LEU A 227 9.381 19.956 15.084 1.00 26.89 H +ATOM 3345 HB3 LEU A 227 9.850 19.773 12.547 1.00 28.85 H +ATOM 3346 HB2 LEU A 227 11.318 18.937 12.962 1.00 28.85 H +ATOM 3347 HG LEU A 227 12.007 20.981 14.322 1.00 34.29 H +ATOM 3348 HD11 LEU A 227 12.043 22.359 11.849 1.00 36.73 H +ATOM 3349 HD12 LEU A 227 13.248 21.261 12.485 1.00 36.73 H +ATOM 3350 HD13 LEU A 227 11.980 20.664 11.421 1.00 36.73 H +ATOM 3351 HD21 LEU A 227 10.441 23.048 13.137 1.00 33.59 H +ATOM 3352 HD22 LEU A 227 9.296 21.866 13.724 1.00 33.59 H +ATOM 3353 HD23 LEU A 227 10.488 22.551 14.816 1.00 33.59 H +ATOM 3354 N MET A 228 9.485 16.762 14.295 1.00 25.26 N +ATOM 3355 CA MET A 228 8.739 15.587 13.838 1.00 24.70 C +ATOM 3356 C MET A 228 8.686 14.531 14.949 1.00 23.35 C +ATOM 3357 O MET A 228 9.711 14.233 15.564 1.00 20.92 O +ATOM 3358 CB MET A 228 9.408 15.055 12.555 1.00 24.08 C +ATOM 3359 CG MET A 228 9.168 15.961 11.334 1.00 24.87 C +ATOM 3360 SD MET A 228 10.164 15.579 9.869 1.00 24.76 S +ATOM 3361 CE MET A 228 11.710 16.421 10.296 1.00 26.75 C +ATOM 3362 H MET A 228 10.463 16.606 14.503 1.00 25.26 H +ATOM 3363 HA MET A 228 7.710 15.854 13.592 1.00 24.70 H +ATOM 3364 HB3 MET A 228 9.025 14.062 12.329 1.00 24.08 H +ATOM 3365 HB2 MET A 228 10.476 14.923 12.717 1.00 24.08 H +ATOM 3366 HG3 MET A 228 9.346 17.007 11.584 1.00 24.87 H +ATOM 3367 HG2 MET A 228 8.119 15.895 11.046 1.00 24.87 H +ATOM 3368 HE1 MET A 228 12.441 16.291 9.498 1.00 26.75 H +ATOM 3369 HE2 MET A 228 11.541 17.488 10.443 1.00 26.75 H +ATOM 3370 HE3 MET A 228 12.121 16.003 11.213 1.00 26.75 H +ATOM 3371 N ASN A 229 7.472 14.008 15.196 1.00 23.78 N +ATOM 3372 CA ASN A 229 7.145 13.104 16.305 1.00 26.25 C +ATOM 3373 C ASN A 229 7.753 11.712 16.102 1.00 24.54 C +ATOM 3374 O ASN A 229 7.451 11.061 15.101 1.00 24.23 O +ATOM 3375 CB ASN A 229 5.610 12.979 16.458 1.00 28.76 C +ATOM 3376 CG ASN A 229 4.848 14.258 16.830 1.00 36.20 C +ATOM 3377 OD1 ASN A 229 3.625 14.278 16.730 1.00 39.05 O +ATOM 3378 ND2 ASN A 229 5.529 15.321 17.270 1.00 36.12 N +ATOM 3379 H ASN A 229 6.691 14.297 14.625 1.00 23.78 H +ATOM 3380 HA ASN A 229 7.558 13.541 17.217 1.00 26.25 H +ATOM 3381 HB3 ASN A 229 5.383 12.247 17.236 1.00 28.76 H +ATOM 3382 HB2 ASN A 229 5.175 12.586 15.537 1.00 28.76 H +ATOM 3383 HD22 ASN A 229 5.033 16.163 17.521 1.00 36.12 H +ATOM 3384 HD21 ASN A 229 6.537 15.300 17.359 1.00 36.12 H +ATOM 3385 N ALA A 230 8.584 11.290 17.072 1.00 23.31 N +ATOM 3386 CA ALA A 230 9.316 10.019 17.096 1.00 22.45 C +ATOM 3387 C ALA A 230 10.159 9.809 15.823 1.00 22.19 C +ATOM 3388 O ALA A 230 10.096 8.743 15.212 1.00 21.45 O +ATOM 3389 CB ALA A 230 8.342 8.859 17.379 1.00 23.18 C +ATOM 3390 H ALA A 230 8.781 11.910 17.844 1.00 23.31 H +ATOM 3391 HA ALA A 230 10.017 10.078 17.928 1.00 22.45 H +ATOM 3392 HB1 ALA A 230 8.873 7.917 17.512 1.00 23.18 H +ATOM 3393 HB2 ALA A 230 7.773 9.040 18.292 1.00 23.18 H +ATOM 3394 HB3 ALA A 230 7.629 8.729 16.567 1.00 23.18 H +ATOM 3395 N TYR A 231 10.893 10.865 15.427 1.00 20.58 N +ATOM 3396 CA TYR A 231 11.648 10.941 14.177 1.00 23.09 C +ATOM 3397 C TYR A 231 12.699 9.831 14.038 1.00 23.15 C +ATOM 3398 O TYR A 231 12.776 9.221 12.977 1.00 21.50 O +ATOM 3399 CB TYR A 231 12.298 12.330 14.036 1.00 21.56 C +ATOM 3400 CG TYR A 231 13.026 12.550 12.723 1.00 22.51 C +ATOM 3401 CD1 TYR A 231 14.422 12.360 12.636 1.00 22.41 C +ATOM 3402 CD2 TYR A 231 12.293 12.898 11.571 1.00 22.80 C +ATOM 3403 CE1 TYR A 231 15.072 12.484 11.394 1.00 26.33 C +ATOM 3404 CE2 TYR A 231 12.946 13.045 10.336 1.00 22.49 C +ATOM 3405 CZ TYR A 231 14.330 12.820 10.244 1.00 23.24 C +ATOM 3406 OH TYR A 231 14.942 12.918 9.032 1.00 25.69 O +ATOM 3407 H TYR A 231 10.889 11.702 15.996 1.00 20.58 H +ATOM 3408 HA TYR A 231 10.930 10.820 13.365 1.00 23.09 H +ATOM 3409 HB3 TYR A 231 13.004 12.479 14.852 1.00 21.56 H +ATOM 3410 HB2 TYR A 231 11.542 13.108 14.131 1.00 21.56 H +ATOM 3411 HD1 TYR A 231 14.993 12.090 13.512 1.00 22.41 H +ATOM 3412 HD2 TYR A 231 11.225 13.034 11.626 1.00 22.80 H +ATOM 3413 HE1 TYR A 231 16.136 12.318 11.326 1.00 26.33 H +ATOM 3414 HE2 TYR A 231 12.381 13.310 9.454 1.00 22.49 H +ATOM 3415 HH TYR A 231 15.826 12.530 9.037 1.00 25.69 H +ATOM 3416 N SER A 232 13.458 9.578 15.115 1.00 22.12 N +ATOM 3417 CA SER A 232 14.523 8.577 15.172 1.00 21.84 C +ATOM 3418 C SER A 232 14.069 7.130 14.895 1.00 21.72 C +ATOM 3419 O SER A 232 14.886 6.351 14.409 1.00 22.45 O +ATOM 3420 CB SER A 232 15.255 8.712 16.523 1.00 21.64 C +ATOM 3421 OG SER A 232 14.455 8.291 17.612 1.00 26.16 O +ATOM 3422 H SER A 232 13.306 10.103 15.965 1.00 22.12 H +ATOM 3423 HA SER A 232 15.235 8.841 14.386 1.00 21.84 H +ATOM 3424 HB3 SER A 232 15.571 9.743 16.688 1.00 21.64 H +ATOM 3425 HB2 SER A 232 16.164 8.108 16.515 1.00 21.64 H +ATOM 3426 HG SER A 232 14.425 7.331 17.616 1.00 26.16 H +ATOM 3427 N SER A 233 12.798 6.807 15.193 1.00 20.41 N +ATOM 3428 CA SER A 233 12.223 5.475 15.018 1.00 20.63 C +ATOM 3429 C SER A 233 11.335 5.334 13.770 1.00 19.00 C +ATOM 3430 O SER A 233 11.184 4.210 13.297 1.00 19.49 O +ATOM 3431 CB SER A 233 11.483 5.075 16.311 1.00 24.24 C +ATOM 3432 OG SER A 233 10.309 5.832 16.529 1.00 29.04 O +ATOM 3433 H SER A 233 12.181 7.506 15.583 1.00 20.41 H +ATOM 3434 HA SER A 233 13.034 4.762 14.890 1.00 20.63 H +ATOM 3435 HB3 SER A 233 12.140 5.172 17.176 1.00 24.24 H +ATOM 3436 HB2 SER A 233 11.190 4.028 16.256 1.00 24.24 H +ATOM 3437 HG SER A 233 9.885 5.511 17.328 1.00 29.04 H +ATOM 3438 N ARG A 234 10.761 6.437 13.263 1.00 18.33 N +ATOM 3439 CA ARG A 234 9.834 6.423 12.126 1.00 22.18 C +ATOM 3440 C ARG A 234 10.484 6.846 10.803 1.00 22.21 C +ATOM 3441 O ARG A 234 9.923 6.518 9.757 1.00 20.94 O +ATOM 3442 CB ARG A 234 8.635 7.335 12.426 1.00 23.89 C +ATOM 3443 CG ARG A 234 7.771 6.850 13.597 1.00 25.44 C +ATOM 3444 CD ARG A 234 6.533 7.735 13.784 1.00 31.15 C +ATOM 3445 NE ARG A 234 5.779 7.372 14.993 1.00 38.50 N +ATOM 3446 CZ ARG A 234 4.777 8.070 15.560 1.00 41.33 C +ATOM 3447 NH1 ARG A 234 4.323 9.221 15.039 1.00 40.07 N +ATOM 3448 NH2 ARG A 234 4.217 7.600 16.681 1.00 42.46 N1+ +ATOM 3449 H ARG A 234 10.909 7.329 13.714 1.00 18.33 H +ATOM 3450 HA ARG A 234 9.444 5.415 11.969 1.00 22.18 H +ATOM 3451 HB3 ARG A 234 8.000 7.413 11.542 1.00 23.89 H +ATOM 3452 HB2 ARG A 234 8.997 8.342 12.632 1.00 23.89 H +ATOM 3453 HG3 ARG A 234 8.335 6.741 14.524 1.00 25.44 H +ATOM 3454 HG2 ARG A 234 7.434 5.847 13.328 1.00 25.44 H +ATOM 3455 HD3 ARG A 234 5.845 7.536 12.961 1.00 31.15 H +ATOM 3456 HD2 ARG A 234 6.785 8.794 13.732 1.00 31.15 H +ATOM 3457 HE ARG A 234 6.063 6.507 15.431 1.00 38.50 H +ATOM 3458 HH12 ARG A 234 3.570 9.728 15.479 1.00 40.07 H +ATOM 3459 HH11 ARG A 234 4.741 9.588 14.196 1.00 40.07 H +ATOM 3460 HH22 ARG A 234 3.464 8.103 17.128 1.00 42.46 H +ATOM 3461 HH21 ARG A 234 4.542 6.736 17.091 1.00 42.46 H +ATOM 3462 N SER A 235 11.627 7.550 10.843 1.00 19.99 N +ATOM 3463 CA SER A 235 12.362 7.927 9.638 1.00 19.86 C +ATOM 3464 C SER A 235 13.190 6.754 9.090 1.00 19.77 C +ATOM 3465 O SER A 235 13.654 5.908 9.854 1.00 20.24 O +ATOM 3466 CB SER A 235 13.218 9.191 9.887 1.00 21.58 C +ATOM 3467 OG SER A 235 14.389 8.940 10.641 1.00 21.88 O +ATOM 3468 H SER A 235 12.049 7.797 11.728 1.00 19.99 H +ATOM 3469 HA SER A 235 11.616 8.202 8.894 1.00 19.86 H +ATOM 3470 HB3 SER A 235 12.630 9.964 10.381 1.00 21.58 H +ATOM 3471 HB2 SER A 235 13.532 9.613 8.932 1.00 21.58 H +ATOM 3472 HG SER A 235 14.132 8.796 11.556 1.00 21.88 H +ATOM 3473 N HIS A 236 13.385 6.775 7.767 1.00 18.17 N +ATOM 3474 CA HIS A 236 14.415 6.021 7.061 1.00 19.29 C +ATOM 3475 C HIS A 236 15.540 7.008 6.739 1.00 18.44 C +ATOM 3476 O HIS A 236 15.240 8.154 6.412 1.00 20.59 O +ATOM 3477 CB HIS A 236 13.838 5.446 5.751 1.00 18.44 C +ATOM 3478 CG HIS A 236 12.567 4.658 5.915 1.00 20.86 C +ATOM 3479 ND1 HIS A 236 12.567 3.288 6.186 1.00 20.53 N +ATOM 3480 CD2 HIS A 236 11.262 5.099 5.848 1.00 19.38 C +ATOM 3481 CE1 HIS A 236 11.289 2.955 6.262 1.00 18.42 C +ATOM 3482 NE2 HIS A 236 10.470 3.991 6.085 1.00 19.60 N +ATOM 3483 H HIS A 236 12.937 7.503 7.225 1.00 18.17 H +ATOM 3484 HA HIS A 236 14.788 5.205 7.682 1.00 19.29 H +ATOM 3485 HB3 HIS A 236 14.579 4.798 5.281 1.00 18.44 H +ATOM 3486 HB2 HIS A 236 13.643 6.244 5.034 1.00 18.44 H +ATOM 3487 HD2 HIS A 236 10.849 6.082 5.670 1.00 19.38 H +ATOM 3488 HE1 HIS A 236 10.952 1.951 6.463 1.00 18.42 H +ATOM 3489 HE2 HIS A 236 9.458 3.974 6.127 1.00 19.60 H +ATOM 3490 N SER A 237 16.795 6.553 6.800 1.00 20.58 N +ATOM 3491 CA SER A 237 17.963 7.337 6.407 1.00 21.26 C +ATOM 3492 C SER A 237 18.805 6.538 5.412 1.00 21.57 C +ATOM 3493 O SER A 237 18.957 5.331 5.575 1.00 20.33 O +ATOM 3494 CB SER A 237 18.746 7.785 7.658 1.00 24.54 C +ATOM 3495 OG SER A 237 19.438 6.740 8.306 1.00 26.90 O +ATOM 3496 H SER A 237 16.979 5.608 7.117 1.00 20.58 H +ATOM 3497 HA SER A 237 17.636 8.238 5.889 1.00 21.26 H +ATOM 3498 HB3 SER A 237 18.080 8.263 8.376 1.00 24.54 H +ATOM 3499 HB2 SER A 237 19.489 8.527 7.370 1.00 24.54 H +ATOM 3500 HG SER A 237 20.153 6.437 7.740 1.00 26.90 H +ATOM 3501 N VAL A 238 19.332 7.242 4.403 1.00 22.05 N +ATOM 3502 CA VAL A 238 20.194 6.705 3.361 1.00 22.38 C +ATOM 3503 C VAL A 238 21.449 7.588 3.345 1.00 23.09 C +ATOM 3504 O VAL A 238 21.437 8.661 2.740 1.00 25.68 O +ATOM 3505 CB VAL A 238 19.505 6.745 1.960 1.00 21.69 C +ATOM 3506 CG1 VAL A 238 20.417 6.244 0.817 1.00 20.82 C +ATOM 3507 CG2 VAL A 238 18.179 5.960 1.947 1.00 20.75 C +ATOM 3508 H VAL A 238 19.125 8.231 4.327 1.00 22.05 H +ATOM 3509 HA VAL A 238 20.492 5.678 3.581 1.00 22.38 H +ATOM 3510 HB VAL A 238 19.240 7.777 1.727 1.00 21.69 H +ATOM 3511 HG11 VAL A 238 19.878 6.212 -0.131 1.00 20.82 H +ATOM 3512 HG12 VAL A 238 21.283 6.888 0.664 1.00 20.82 H +ATOM 3513 HG13 VAL A 238 20.787 5.239 1.019 1.00 20.82 H +ATOM 3514 HG21 VAL A 238 17.729 5.956 0.953 1.00 20.75 H +ATOM 3515 HG22 VAL A 238 18.326 4.924 2.248 1.00 20.75 H +ATOM 3516 HG23 VAL A 238 17.448 6.400 2.625 1.00 20.75 H +ATOM 3517 N PHE A 239 22.506 7.123 4.030 1.00 25.74 N +ATOM 3518 CA PHE A 239 23.827 7.740 3.977 1.00 25.50 C +ATOM 3519 C PHE A 239 24.558 7.114 2.787 1.00 27.21 C +ATOM 3520 O PHE A 239 24.990 5.967 2.888 1.00 25.60 O +ATOM 3521 CB PHE A 239 24.578 7.511 5.311 1.00 24.56 C +ATOM 3522 CG PHE A 239 25.854 8.329 5.462 1.00 23.56 C +ATOM 3523 CD1 PHE A 239 27.025 7.986 4.751 1.00 24.94 C +ATOM 3524 CD2 PHE A 239 25.838 9.529 6.207 1.00 23.03 C +ATOM 3525 CE1 PHE A 239 28.138 8.812 4.803 1.00 25.28 C +ATOM 3526 CE2 PHE A 239 26.973 10.326 6.270 1.00 24.84 C +ATOM 3527 CZ PHE A 239 28.118 9.970 5.570 1.00 24.20 C +ATOM 3528 H PHE A 239 22.445 6.239 4.520 1.00 25.74 H +ATOM 3529 HA PHE A 239 23.731 8.815 3.829 1.00 25.50 H +ATOM 3530 HB3 PHE A 239 24.830 6.458 5.432 1.00 24.56 H +ATOM 3531 HB2 PHE A 239 23.920 7.740 6.149 1.00 24.56 H +ATOM 3532 HD1 PHE A 239 27.060 7.091 4.149 1.00 24.94 H +ATOM 3533 HD2 PHE A 239 24.948 9.833 6.737 1.00 23.03 H +ATOM 3534 HE1 PHE A 239 29.017 8.553 4.233 1.00 25.28 H +ATOM 3535 HE2 PHE A 239 26.959 11.237 6.851 1.00 24.84 H +ATOM 3536 HZ PHE A 239 28.992 10.604 5.608 1.00 24.20 H +ATOM 3537 N SER A 240 24.678 7.865 1.684 1.00 28.35 N +ATOM 3538 CA SER A 240 25.437 7.427 0.520 1.00 31.42 C +ATOM 3539 C SER A 240 26.833 8.061 0.527 1.00 32.07 C +ATOM 3540 O SER A 240 26.976 9.215 0.929 1.00 32.25 O +ATOM 3541 CB SER A 240 24.635 7.678 -0.772 1.00 34.03 C +ATOM 3542 OG SER A 240 24.801 8.961 -1.338 1.00 40.12 O +ATOM 3543 H SER A 240 24.334 8.817 1.676 1.00 28.35 H +ATOM 3544 HA SER A 240 25.557 6.350 0.576 1.00 31.42 H +ATOM 3545 HB3 SER A 240 23.573 7.482 -0.617 1.00 34.03 H +ATOM 3546 HB2 SER A 240 24.974 6.957 -1.515 1.00 34.03 H +ATOM 3547 HG SER A 240 24.336 9.607 -0.796 1.00 40.12 H +ATOM 3548 N VAL A 241 27.817 7.288 0.052 1.00 33.55 N +ATOM 3549 CA VAL A 241 29.173 7.736 -0.231 1.00 34.45 C +ATOM 3550 C VAL A 241 29.516 7.325 -1.670 1.00 34.62 C +ATOM 3551 O VAL A 241 29.385 6.151 -2.006 1.00 35.51 O +ATOM 3552 CB VAL A 241 30.218 7.168 0.778 1.00 34.83 C +ATOM 3553 CG1 VAL A 241 30.239 5.637 0.921 1.00 38.79 C +ATOM 3554 CG2 VAL A 241 31.645 7.669 0.487 1.00 35.64 C +ATOM 3555 H VAL A 241 27.608 6.336 -0.224 1.00 33.55 H +ATOM 3556 HA VAL A 241 29.205 8.822 -0.168 1.00 34.45 H +ATOM 3557 HB VAL A 241 29.942 7.557 1.759 1.00 34.83 H +ATOM 3558 HG11 VAL A 241 30.890 5.333 1.741 1.00 38.79 H +ATOM 3559 HG12 VAL A 241 29.247 5.242 1.140 1.00 38.79 H +ATOM 3560 HG13 VAL A 241 30.619 5.155 0.020 1.00 38.79 H +ATOM 3561 HG21 VAL A 241 32.356 7.285 1.217 1.00 35.64 H +ATOM 3562 HG22 VAL A 241 32.007 7.357 -0.493 1.00 35.64 H +ATOM 3563 HG23 VAL A 241 31.682 8.757 0.528 1.00 35.64 H +ATOM 3564 N THR A 242 29.937 8.305 -2.483 1.00 35.79 N +ATOM 3565 CA THR A 242 30.386 8.109 -3.859 1.00 37.70 C +ATOM 3566 C THR A 242 31.881 8.444 -3.934 1.00 37.87 C +ATOM 3567 O THR A 242 32.287 9.492 -3.432 1.00 37.49 O +ATOM 3568 CB THR A 242 29.638 9.035 -4.853 1.00 37.97 C +ATOM 3569 OG1 THR A 242 28.251 8.772 -4.771 1.00 39.56 O +ATOM 3570 CG2 THR A 242 30.056 8.873 -6.329 1.00 37.97 C +ATOM 3571 H THR A 242 30.018 9.247 -2.121 1.00 35.79 H +ATOM 3572 HA THR A 242 30.233 7.075 -4.163 1.00 37.70 H +ATOM 3573 HB THR A 242 29.780 10.077 -4.562 1.00 37.97 H +ATOM 3574 HG1 THR A 242 27.942 9.076 -3.910 1.00 39.56 H +ATOM 3575 HG21 THR A 242 29.443 9.500 -6.978 1.00 37.97 H +ATOM 3576 HG22 THR A 242 31.093 9.162 -6.497 1.00 37.97 H +ATOM 3577 HG23 THR A 242 29.940 7.842 -6.663 1.00 37.97 H +ATOM 3578 N ILE A 243 32.662 7.550 -4.557 1.00 39.49 N +ATOM 3579 CA ILE A 243 34.109 7.678 -4.676 1.00 41.33 C +ATOM 3580 C ILE A 243 34.449 7.701 -6.177 1.00 42.69 C +ATOM 3581 O ILE A 243 34.334 6.678 -6.850 1.00 41.59 O +ATOM 3582 CB ILE A 243 34.876 6.490 -4.019 1.00 42.17 C +ATOM 3583 CG1 ILE A 243 34.339 6.106 -2.620 1.00 40.50 C +ATOM 3584 CG2 ILE A 243 36.390 6.787 -3.930 1.00 40.47 C +ATOM 3585 CD1 ILE A 243 34.920 4.783 -2.110 1.00 41.65 C +ATOM 3586 H ILE A 243 32.248 6.725 -4.976 1.00 39.49 H +ATOM 3587 HA ILE A 243 34.458 8.602 -4.216 1.00 41.33 H +ATOM 3588 HB ILE A 243 34.752 5.605 -4.645 1.00 42.17 H +ATOM 3589 HG13 ILE A 243 33.255 5.995 -2.632 1.00 40.50 H +ATOM 3590 HG12 ILE A 243 34.550 6.905 -1.908 1.00 40.50 H +ATOM 3591 HG21 ILE A 243 36.951 5.895 -3.657 1.00 40.47 H +ATOM 3592 HG22 ILE A 243 36.803 7.155 -4.866 1.00 40.47 H +ATOM 3593 HG23 ILE A 243 36.598 7.551 -3.181 1.00 40.47 H +ATOM 3594 HD11 ILE A 243 34.284 4.344 -1.342 1.00 41.65 H +ATOM 3595 HD12 ILE A 243 35.006 4.057 -2.917 1.00 41.65 H +ATOM 3596 HD13 ILE A 243 35.912 4.930 -1.687 1.00 41.65 H +ATOM 3597 N HIS A 244 34.874 8.872 -6.667 1.00 44.46 N +ATOM 3598 CA HIS A 244 35.465 9.037 -7.994 1.00 47.53 C +ATOM 3599 C HIS A 244 36.957 8.733 -7.886 1.00 47.71 C +ATOM 3600 O HIS A 244 37.603 9.276 -6.996 1.00 47.71 O +ATOM 3601 CB HIS A 244 35.233 10.474 -8.489 1.00 49.46 C +ATOM 3602 CG HIS A 244 33.777 10.794 -8.685 1.00 52.62 C +ATOM 3603 ND1 HIS A 244 33.068 10.377 -9.815 1.00 53.91 N +ATOM 3604 CD2 HIS A 244 32.917 11.459 -7.836 1.00 52.34 C +ATOM 3605 CE1 HIS A 244 31.825 10.785 -9.607 1.00 52.76 C +ATOM 3606 NE2 HIS A 244 31.678 11.428 -8.450 1.00 53.06 N +ATOM 3607 H HIS A 244 34.966 9.663 -6.042 1.00 44.46 H +ATOM 3608 HA HIS A 244 35.003 8.345 -8.703 1.00 47.53 H +ATOM 3609 HB3 HIS A 244 35.744 10.631 -9.440 1.00 49.46 H +ATOM 3610 HB2 HIS A 244 35.656 11.195 -7.789 1.00 49.46 H +ATOM 3611 HD2 HIS A 244 33.081 11.910 -6.869 1.00 52.34 H +ATOM 3612 HE1 HIS A 244 31.016 10.606 -10.300 1.00 52.76 H +ATOM 3613 HE2 HIS A 244 30.815 11.798 -8.084 1.00 53.06 H +ATOM 3614 N MET A 245 37.457 7.850 -8.758 1.00 48.94 N +ATOM 3615 CA MET A 245 38.824 7.338 -8.731 1.00 49.37 C +ATOM 3616 C MET A 245 39.421 7.438 -10.134 1.00 51.21 C +ATOM 3617 O MET A 245 38.759 7.086 -11.108 1.00 50.79 O +ATOM 3618 CB MET A 245 38.819 5.865 -8.272 1.00 47.53 C +ATOM 3619 CG MET A 245 38.271 5.654 -6.855 1.00 47.54 C +ATOM 3620 SD MET A 245 37.955 3.929 -6.414 1.00 44.84 S +ATOM 3621 CE MET A 245 36.293 3.751 -7.119 1.00 45.83 C +ATOM 3622 H MET A 245 36.852 7.437 -9.457 1.00 48.94 H +ATOM 3623 HA MET A 245 39.444 7.918 -8.045 1.00 49.37 H +ATOM 3624 HB3 MET A 245 39.834 5.467 -8.312 1.00 47.53 H +ATOM 3625 HB2 MET A 245 38.237 5.267 -8.972 1.00 47.53 H +ATOM 3626 HG3 MET A 245 37.325 6.176 -6.737 1.00 47.54 H +ATOM 3627 HG2 MET A 245 38.961 6.087 -6.134 1.00 47.54 H +ATOM 3628 HE1 MET A 245 35.952 2.719 -7.071 1.00 45.83 H +ATOM 3629 HE2 MET A 245 35.584 4.362 -6.562 1.00 45.83 H +ATOM 3630 HE3 MET A 245 36.276 4.068 -8.160 1.00 45.83 H +ATOM 3631 N LYS A 246 40.684 7.866 -10.183 1.00 52.65 N +ATOM 3632 CA LYS A 246 41.535 7.895 -11.359 1.00 54.10 C +ATOM 3633 C LYS A 246 42.818 7.169 -10.943 1.00 54.52 C +ATOM 3634 O LYS A 246 43.819 7.799 -10.602 1.00 54.51 O +ATOM 3635 CB LYS A 246 41.739 9.358 -11.806 1.00 54.81 C +ATOM 3636 CG LYS A 246 42.485 9.497 -13.141 1.00 57.30 C +ATOM 3637 CD LYS A 246 42.701 10.970 -13.530 1.00 58.78 C +ATOM 3638 CE LYS A 246 43.164 11.179 -14.981 1.00 60.80 C +ATOM 3639 NZ LYS A 246 42.095 10.892 -15.956 1.00 61.59 N1+ +ATOM 3640 H LYS A 246 41.126 8.187 -9.332 1.00 52.65 H +ATOM 3641 HA LYS A 246 41.081 7.338 -12.181 1.00 54.10 H +ATOM 3642 HB3 LYS A 246 42.254 9.926 -11.031 1.00 54.81 H +ATOM 3643 HB2 LYS A 246 40.760 9.829 -11.914 1.00 54.81 H +ATOM 3644 HG3 LYS A 246 41.921 8.974 -13.913 1.00 57.30 H +ATOM 3645 HG2 LYS A 246 43.454 9.000 -13.088 1.00 57.30 H +ATOM 3646 HD3 LYS A 246 43.469 11.377 -12.874 1.00 58.78 H +ATOM 3647 HD2 LYS A 246 41.801 11.554 -13.329 1.00 58.78 H +ATOM 3648 HE3 LYS A 246 44.032 10.555 -15.198 1.00 60.80 H +ATOM 3649 HE2 LYS A 246 43.476 12.215 -15.118 1.00 60.80 H +ATOM 3650 HZ1 LYS A 246 41.307 11.498 -15.780 1.00 61.59 H +ATOM 3651 HZ2 LYS A 246 42.444 11.052 -16.890 1.00 61.59 H +ATOM 3652 HZ3 LYS A 246 41.808 9.928 -15.866 1.00 61.59 H +ATOM 3653 N GLU A 247 42.715 5.832 -10.913 1.00 55.12 N +ATOM 3654 CA GLU A 247 43.784 4.911 -10.550 1.00 56.95 C +ATOM 3655 C GLU A 247 44.915 4.946 -11.578 1.00 58.47 C +ATOM 3656 O GLU A 247 44.640 4.787 -12.762 1.00 58.51 O +ATOM 3657 CB GLU A 247 43.189 3.496 -10.407 1.00 56.93 C +ATOM 3658 CG GLU A 247 44.225 2.401 -10.073 1.00 58.97 C +ATOM 3659 CD GLU A 247 43.569 1.035 -9.857 1.00 60.88 C +ATOM 3660 OE1 GLU A 247 42.999 0.506 -10.837 1.00 62.91 O +ATOM 3661 OE2 GLU A 247 43.629 0.548 -8.706 1.00 61.38 O1- +ATOM 3662 H GLU A 247 41.860 5.400 -11.234 1.00 55.12 H +ATOM 3663 HA GLU A 247 44.178 5.209 -9.579 1.00 56.95 H +ATOM 3664 HB3 GLU A 247 42.663 3.231 -11.326 1.00 56.93 H +ATOM 3665 HB2 GLU A 247 42.429 3.516 -9.626 1.00 56.93 H +ATOM 3666 HG3 GLU A 247 44.795 2.691 -9.188 1.00 58.97 H +ATOM 3667 HG2 GLU A 247 44.950 2.292 -10.880 1.00 58.97 H +ATOM 3668 N THR A 248 46.150 5.112 -11.092 1.00 59.07 N +ATOM 3669 CA THR A 248 47.364 5.048 -11.894 1.00 60.38 C +ATOM 3670 C THR A 248 48.174 3.841 -11.380 1.00 60.78 C +ATOM 3671 O THR A 248 49.039 3.969 -10.512 1.00 60.10 O +ATOM 3672 CB THR A 248 48.164 6.380 -11.808 1.00 61.01 C +ATOM 3673 OG1 THR A 248 48.631 6.673 -10.505 1.00 63.16 O +ATOM 3674 CG2 THR A 248 47.349 7.593 -12.286 1.00 61.02 C +ATOM 3675 H THR A 248 46.288 5.253 -10.101 1.00 59.07 H +ATOM 3676 HA THR A 248 47.135 4.874 -12.946 1.00 60.38 H +ATOM 3677 HB THR A 248 49.041 6.290 -12.451 1.00 61.01 H +ATOM 3678 HG1 THR A 248 49.173 5.935 -10.211 1.00 63.16 H +ATOM 3679 HG21 THR A 248 46.540 7.829 -11.593 1.00 61.02 H +ATOM 3680 HG22 THR A 248 47.976 8.481 -12.372 1.00 61.02 H +ATOM 3681 HG23 THR A 248 46.897 7.411 -13.258 1.00 61.02 H +ATOM 3682 N THR A 249 47.830 2.661 -11.924 1.00 61.35 N +ATOM 3683 CA THR A 249 48.451 1.356 -11.655 1.00 61.85 C +ATOM 3684 C THR A 249 49.974 1.367 -11.930 1.00 61.20 C +ATOM 3685 O THR A 249 50.436 2.222 -12.687 1.00 61.63 O +ATOM 3686 CB THR A 249 47.775 0.282 -12.555 1.00 62.62 C +ATOM 3687 OG1 THR A 249 46.380 0.301 -12.329 1.00 63.50 O +ATOM 3688 CG2 THR A 249 48.237 -1.174 -12.374 1.00 63.08 C +ATOM 3689 H THR A 249 47.096 2.643 -12.619 1.00 61.35 H +ATOM 3690 HA THR A 249 48.287 1.113 -10.603 1.00 61.85 H +ATOM 3691 HB THR A 249 47.925 0.556 -13.600 1.00 62.62 H +ATOM 3692 HG1 THR A 249 45.978 -0.434 -12.800 1.00 63.50 H +ATOM 3693 HG21 THR A 249 49.255 -1.308 -12.728 1.00 63.08 H +ATOM 3694 HG22 THR A 249 48.182 -1.491 -11.333 1.00 63.08 H +ATOM 3695 HG23 THR A 249 47.620 -1.853 -12.965 1.00 63.08 H +ATOM 3696 N ILE A 250 50.739 0.444 -11.314 1.00 60.81 N +ATOM 3697 CA ILE A 250 52.208 0.371 -11.433 1.00 60.26 C +ATOM 3698 C ILE A 250 52.738 0.202 -12.880 1.00 60.18 C +ATOM 3699 O ILE A 250 53.884 0.564 -13.145 1.00 60.31 O +ATOM 3700 CB ILE A 250 52.833 -0.742 -10.532 1.00 60.33 C +ATOM 3701 CG1 ILE A 250 52.798 -2.204 -11.054 1.00 59.91 C +ATOM 3702 CG2 ILE A 250 52.350 -0.643 -9.073 1.00 59.68 C +ATOM 3703 CD1 ILE A 250 51.405 -2.813 -11.267 1.00 59.13 C +ATOM 3704 H ILE A 250 50.309 -0.236 -10.705 1.00 60.81 H +ATOM 3705 HA ILE A 250 52.589 1.331 -11.079 1.00 60.26 H +ATOM 3706 HB ILE A 250 53.896 -0.500 -10.486 1.00 60.33 H +ATOM 3707 HG13 ILE A 250 53.348 -2.837 -10.358 1.00 59.91 H +ATOM 3708 HG12 ILE A 250 53.356 -2.284 -11.988 1.00 59.91 H +ATOM 3709 HG21 ILE A 250 52.903 -1.328 -8.430 1.00 59.68 H +ATOM 3710 HG22 ILE A 250 52.501 0.364 -8.681 1.00 59.68 H +ATOM 3711 HG23 ILE A 250 51.292 -0.878 -8.971 1.00 59.68 H +ATOM 3712 HD11 ILE A 250 51.460 -3.901 -11.245 1.00 59.13 H +ATOM 3713 HD12 ILE A 250 50.690 -2.503 -10.506 1.00 59.13 H +ATOM 3714 HD13 ILE A 250 51.009 -2.537 -12.240 1.00 59.13 H +ATOM 3715 N ASP A 251 51.877 -0.296 -13.783 1.00 60.25 N +ATOM 3716 CA ASP A 251 52.093 -0.443 -15.227 1.00 60.38 C +ATOM 3717 C ASP A 251 51.906 0.869 -16.021 1.00 59.91 C +ATOM 3718 O ASP A 251 52.124 0.866 -17.232 1.00 60.56 O +ATOM 3719 CB ASP A 251 51.210 -1.577 -15.810 1.00 60.98 C +ATOM 3720 CG ASP A 251 51.362 -2.949 -15.123 1.00 62.11 C +ATOM 3721 OD1 ASP A 251 52.484 -3.264 -14.662 1.00 61.91 O +ATOM 3722 OD2 ASP A 251 50.386 -3.726 -15.198 1.00 62.45 O1- +ATOM 3723 H ASP A 251 50.959 -0.569 -13.462 1.00 60.25 H +ATOM 3724 HA ASP A 251 53.135 -0.719 -15.386 1.00 60.38 H +ATOM 3725 HB3 ASP A 251 51.435 -1.722 -16.868 1.00 60.98 H +ATOM 3726 HB2 ASP A 251 50.162 -1.280 -15.744 1.00 60.98 H +ATOM 3727 N GLY A 252 51.533 1.965 -15.340 1.00 59.46 N +ATOM 3728 CA GLY A 252 51.425 3.314 -15.890 1.00 58.92 C +ATOM 3729 C GLY A 252 50.054 3.604 -16.519 1.00 59.26 C +ATOM 3730 O GLY A 252 49.792 4.764 -16.834 1.00 59.89 O +ATOM 3731 H GLY A 252 51.351 1.878 -14.347 1.00 59.46 H +ATOM 3732 HA3 GLY A 252 52.207 3.491 -16.631 1.00 58.92 H +ATOM 3733 HA2 GLY A 252 51.593 4.024 -15.080 1.00 58.92 H +ATOM 3734 N GLU A 253 49.181 2.592 -16.697 1.00 59.20 N +ATOM 3735 CA GLU A 253 47.828 2.766 -17.232 1.00 59.24 C +ATOM 3736 C GLU A 253 46.901 3.473 -16.229 1.00 59.28 C +ATOM 3737 O GLU A 253 46.977 3.209 -15.027 1.00 59.03 O +ATOM 3738 CB GLU A 253 47.239 1.422 -17.710 1.00 58.97 C +ATOM 3739 CG GLU A 253 47.239 0.276 -16.668 1.00 60.46 C +ATOM 3740 CD GLU A 253 46.358 -0.937 -17.017 1.00 61.44 C +ATOM 3741 OE1 GLU A 253 46.334 -1.858 -16.171 1.00 62.15 O +ATOM 3742 OE2 GLU A 253 45.713 -0.943 -18.091 1.00 61.94 O1- +ATOM 3743 H GLU A 253 49.438 1.656 -16.422 1.00 59.20 H +ATOM 3744 HA GLU A 253 47.908 3.405 -18.115 1.00 59.24 H +ATOM 3745 HB3 GLU A 253 47.776 1.095 -18.601 1.00 58.97 H +ATOM 3746 HB2 GLU A 253 46.218 1.616 -18.042 1.00 58.97 H +ATOM 3747 HG3 GLU A 253 46.911 0.649 -15.699 1.00 60.46 H +ATOM 3748 HG2 GLU A 253 48.261 -0.074 -16.521 1.00 60.46 H +ATOM 3749 N GLU A 254 46.051 4.360 -16.766 1.00 59.88 N +ATOM 3750 CA GLU A 254 45.186 5.249 -15.999 1.00 60.07 C +ATOM 3751 C GLU A 254 43.718 4.831 -16.186 1.00 59.53 C +ATOM 3752 O GLU A 254 43.112 5.189 -17.197 1.00 59.70 O +ATOM 3753 CB GLU A 254 45.443 6.709 -16.427 1.00 61.29 C +ATOM 3754 CG GLU A 254 46.924 7.132 -16.311 1.00 62.36 C +ATOM 3755 CD GLU A 254 47.130 8.637 -16.518 1.00 63.74 C +ATOM 3756 OE1 GLU A 254 46.738 9.130 -17.600 1.00 64.15 O +ATOM 3757 OE2 GLU A 254 47.679 9.276 -15.594 1.00 63.61 O1- +ATOM 3758 H GLU A 254 46.043 4.499 -17.766 1.00 59.88 H +ATOM 3759 HA GLU A 254 45.447 5.191 -14.948 1.00 60.07 H +ATOM 3760 HB3 GLU A 254 44.829 7.369 -15.813 1.00 61.29 H +ATOM 3761 HB2 GLU A 254 45.111 6.858 -17.456 1.00 61.29 H +ATOM 3762 HG3 GLU A 254 47.521 6.610 -17.060 1.00 62.36 H +ATOM 3763 HG2 GLU A 254 47.330 6.821 -15.348 1.00 62.36 H +ATOM 3764 N LEU A 255 43.180 4.067 -15.219 1.00 58.86 N +ATOM 3765 CA LEU A 255 41.805 3.560 -15.232 1.00 58.29 C +ATOM 3766 C LEU A 255 40.913 4.453 -14.360 1.00 57.75 C +ATOM 3767 O LEU A 255 41.251 4.697 -13.202 1.00 57.53 O +ATOM 3768 CB LEU A 255 41.739 2.102 -14.708 1.00 58.62 C +ATOM 3769 CG LEU A 255 42.695 1.080 -15.367 1.00 59.01 C +ATOM 3770 CD1 LEU A 255 42.701 1.131 -16.908 1.00 58.57 C +ATOM 3771 CD2 LEU A 255 44.110 1.121 -14.761 1.00 59.86 C +ATOM 3772 H LEU A 255 43.733 3.839 -14.403 1.00 58.86 H +ATOM 3773 HA LEU A 255 41.415 3.576 -16.252 1.00 58.29 H +ATOM 3774 HB3 LEU A 255 40.718 1.748 -14.855 1.00 58.62 H +ATOM 3775 HB2 LEU A 255 41.892 2.077 -13.627 1.00 58.62 H +ATOM 3776 HG LEU A 255 42.291 0.103 -15.096 1.00 59.01 H +ATOM 3777 HD11 LEU A 255 42.773 0.126 -17.324 1.00 58.57 H +ATOM 3778 HD12 LEU A 255 41.789 1.575 -17.307 1.00 58.57 H +ATOM 3779 HD13 LEU A 255 43.542 1.705 -17.299 1.00 58.57 H +ATOM 3780 HD21 LEU A 255 44.449 0.119 -14.496 1.00 59.86 H +ATOM 3781 HD22 LEU A 255 44.831 1.533 -15.462 1.00 59.86 H +ATOM 3782 HD23 LEU A 255 44.162 1.728 -13.856 1.00 59.86 H +ATOM 3783 N VAL A 256 39.772 4.886 -14.918 1.00 57.07 N +ATOM 3784 CA VAL A 256 38.769 5.674 -14.203 1.00 55.73 C +ATOM 3785 C VAL A 256 37.654 4.739 -13.697 1.00 54.78 C +ATOM 3786 O VAL A 256 37.149 3.923 -14.470 1.00 54.63 O +ATOM 3787 CB VAL A 256 38.147 6.774 -15.109 1.00 56.83 C +ATOM 3788 CG1 VAL A 256 37.027 7.586 -14.422 1.00 57.15 C +ATOM 3789 CG2 VAL A 256 39.229 7.743 -15.624 1.00 57.77 C +ATOM 3790 H VAL A 256 39.545 4.628 -15.868 1.00 57.07 H +ATOM 3791 HA VAL A 256 39.237 6.171 -13.355 1.00 55.73 H +ATOM 3792 HB VAL A 256 37.708 6.293 -15.984 1.00 56.83 H +ATOM 3793 HG11 VAL A 256 36.685 8.401 -15.061 1.00 57.15 H +ATOM 3794 HG12 VAL A 256 36.150 6.978 -14.200 1.00 57.15 H +ATOM 3795 HG13 VAL A 256 37.374 8.025 -13.486 1.00 57.15 H +ATOM 3796 HG21 VAL A 256 38.797 8.514 -16.263 1.00 57.77 H +ATOM 3797 HG22 VAL A 256 39.733 8.243 -14.796 1.00 57.77 H +ATOM 3798 HG23 VAL A 256 39.988 7.228 -16.213 1.00 57.77 H +ATOM 3799 N LYS A 257 37.297 4.882 -12.411 1.00 51.70 N +ATOM 3800 CA LYS A 257 36.267 4.096 -11.731 1.00 48.93 C +ATOM 3801 C LYS A 257 35.394 5.013 -10.863 1.00 46.97 C +ATOM 3802 O LYS A 257 35.898 5.988 -10.307 1.00 45.71 O +ATOM 3803 CB LYS A 257 36.932 3.004 -10.863 1.00 50.03 C +ATOM 3804 CG LYS A 257 37.610 1.885 -11.674 1.00 50.79 C +ATOM 3805 CD LYS A 257 38.182 0.733 -10.824 1.00 50.90 C +ATOM 3806 CE LYS A 257 39.599 0.953 -10.258 1.00 50.77 C +ATOM 3807 NZ LYS A 257 39.631 1.866 -9.101 1.00 52.08 N1+ +ATOM 3808 H LYS A 257 37.745 5.597 -11.851 1.00 51.70 H +ATOM 3809 HA LYS A 257 35.617 3.621 -12.468 1.00 48.93 H +ATOM 3810 HB3 LYS A 257 36.171 2.541 -10.233 1.00 50.03 H +ATOM 3811 HB2 LYS A 257 37.646 3.464 -10.184 1.00 50.03 H +ATOM 3812 HG3 LYS A 257 38.403 2.295 -12.300 1.00 50.79 H +ATOM 3813 HG2 LYS A 257 36.874 1.470 -12.364 1.00 50.79 H +ATOM 3814 HD3 LYS A 257 38.185 -0.176 -11.428 1.00 50.90 H +ATOM 3815 HD2 LYS A 257 37.501 0.527 -10.001 1.00 50.90 H +ATOM 3816 HE3 LYS A 257 40.268 1.325 -11.034 1.00 50.77 H +ATOM 3817 HE2 LYS A 257 40.004 -0.002 -9.923 1.00 50.77 H +ATOM 3818 HZ1 LYS A 257 39.030 1.505 -8.371 1.00 52.08 H +ATOM 3819 HZ2 LYS A 257 40.576 1.935 -8.747 1.00 52.08 H +ATOM 3820 HZ3 LYS A 257 39.307 2.780 -9.379 1.00 52.08 H +ATOM 3821 N ILE A 258 34.106 4.658 -10.739 1.00 44.56 N +ATOM 3822 CA ILE A 258 33.141 5.328 -9.869 1.00 42.44 C +ATOM 3823 C ILE A 258 32.493 4.263 -8.973 1.00 40.52 C +ATOM 3824 O ILE A 258 31.740 3.424 -9.467 1.00 38.13 O +ATOM 3825 CB ILE A 258 32.027 6.079 -10.663 1.00 43.22 C +ATOM 3826 CG1 ILE A 258 32.645 7.190 -11.544 1.00 43.77 C +ATOM 3827 CG2 ILE A 258 30.926 6.672 -9.747 1.00 45.13 C +ATOM 3828 CD1 ILE A 258 31.642 7.914 -12.454 1.00 43.79 C +ATOM 3829 H ILE A 258 33.760 3.844 -11.234 1.00 44.56 H +ATOM 3830 HA ILE A 258 33.644 6.058 -9.234 1.00 42.44 H +ATOM 3831 HB ILE A 258 31.547 5.364 -11.335 1.00 43.22 H +ATOM 3832 HG13 ILE A 258 33.426 6.775 -12.181 1.00 43.77 H +ATOM 3833 HG12 ILE A 258 33.145 7.917 -10.906 1.00 43.77 H +ATOM 3834 HG21 ILE A 258 30.165 7.201 -10.320 1.00 45.13 H +ATOM 3835 HG22 ILE A 258 30.392 5.911 -9.178 1.00 45.13 H +ATOM 3836 HG23 ILE A 258 31.351 7.380 -9.034 1.00 45.13 H +ATOM 3837 HD11 ILE A 258 32.147 8.348 -13.316 1.00 43.79 H +ATOM 3838 HD12 ILE A 258 30.876 7.234 -12.828 1.00 43.79 H +ATOM 3839 HD13 ILE A 258 31.143 8.726 -11.925 1.00 43.79 H +ATOM 3840 N GLY A 259 32.801 4.332 -7.672 1.00 37.82 N +ATOM 3841 CA GLY A 259 32.202 3.496 -6.640 1.00 36.40 C +ATOM 3842 C GLY A 259 31.053 4.262 -5.984 1.00 34.07 C +ATOM 3843 O GLY A 259 31.104 5.487 -5.890 1.00 31.38 O +ATOM 3844 H GLY A 259 33.422 5.067 -7.355 1.00 37.82 H +ATOM 3845 HA3 GLY A 259 32.954 3.321 -5.874 1.00 36.40 H +ATOM 3846 HA2 GLY A 259 31.876 2.528 -7.023 1.00 36.40 H +ATOM 3847 N LYS A 260 30.053 3.529 -5.474 1.00 34.92 N +ATOM 3848 CA LYS A 260 28.978 4.071 -4.644 1.00 35.62 C +ATOM 3849 C LYS A 260 28.524 3.011 -3.631 1.00 34.43 C +ATOM 3850 O LYS A 260 28.368 1.848 -3.994 1.00 33.78 O +ATOM 3851 CB LYS A 260 27.843 4.620 -5.535 1.00 38.36 C +ATOM 3852 CG LYS A 260 26.584 5.118 -4.799 1.00 43.96 C +ATOM 3853 CD LYS A 260 25.539 5.668 -5.789 1.00 46.47 C +ATOM 3854 CE LYS A 260 24.143 5.904 -5.188 1.00 47.84 C +ATOM 3855 NZ LYS A 260 24.126 6.991 -4.194 1.00 49.34 N1+ +ATOM 3856 H LYS A 260 30.055 2.524 -5.588 1.00 34.92 H +ATOM 3857 HA LYS A 260 29.389 4.904 -4.081 1.00 35.62 H +ATOM 3858 HB3 LYS A 260 27.538 3.834 -6.221 1.00 38.36 H +ATOM 3859 HB2 LYS A 260 28.235 5.428 -6.153 1.00 38.36 H +ATOM 3860 HG3 LYS A 260 26.861 5.884 -4.074 1.00 43.96 H +ATOM 3861 HG2 LYS A 260 26.135 4.301 -4.233 1.00 43.96 H +ATOM 3862 HD3 LYS A 260 25.439 4.972 -6.623 1.00 46.47 H +ATOM 3863 HD2 LYS A 260 25.914 6.594 -6.227 1.00 46.47 H +ATOM 3864 HE3 LYS A 260 23.769 4.990 -4.727 1.00 47.84 H +ATOM 3865 HE2 LYS A 260 23.443 6.165 -5.982 1.00 47.84 H +ATOM 3866 HZ1 LYS A 260 24.433 7.853 -4.623 1.00 49.34 H +ATOM 3867 HZ2 LYS A 260 23.190 7.109 -3.834 1.00 49.34 H +ATOM 3868 HZ3 LYS A 260 24.746 6.759 -3.432 1.00 49.34 H +ATOM 3869 N LEU A 261 28.303 3.443 -2.382 1.00 33.81 N +ATOM 3870 CA LEU A 261 27.833 2.610 -1.279 1.00 31.60 C +ATOM 3871 C LEU A 261 26.693 3.348 -0.570 1.00 29.63 C +ATOM 3872 O LEU A 261 26.902 4.487 -0.160 1.00 29.87 O +ATOM 3873 CB LEU A 261 29.019 2.310 -0.339 1.00 29.94 C +ATOM 3874 CG LEU A 261 28.707 1.493 0.936 1.00 31.43 C +ATOM 3875 CD1 LEU A 261 28.100 0.114 0.637 1.00 27.52 C +ATOM 3876 CD2 LEU A 261 29.960 1.351 1.820 1.00 29.62 C +ATOM 3877 H LEU A 261 28.470 4.416 -2.158 1.00 33.81 H +ATOM 3878 HA LEU A 261 27.465 1.662 -1.659 1.00 31.60 H +ATOM 3879 HB3 LEU A 261 29.463 3.253 -0.035 1.00 29.94 H +ATOM 3880 HB2 LEU A 261 29.794 1.809 -0.911 1.00 29.94 H +ATOM 3881 HG LEU A 261 27.977 2.052 1.518 1.00 31.43 H +ATOM 3882 HD11 LEU A 261 28.088 -0.516 1.527 1.00 27.52 H +ATOM 3883 HD12 LEU A 261 27.070 0.195 0.288 1.00 27.52 H +ATOM 3884 HD13 LEU A 261 28.681 -0.408 -0.118 1.00 27.52 H +ATOM 3885 HD21 LEU A 261 30.315 0.320 1.865 1.00 29.62 H +ATOM 3886 HD22 LEU A 261 30.791 1.955 1.455 1.00 29.62 H +ATOM 3887 HD23 LEU A 261 29.750 1.662 2.843 1.00 29.62 H +ATOM 3888 N ASN A 262 25.536 2.685 -0.416 1.00 30.06 N +ATOM 3889 CA ASN A 262 24.382 3.200 0.329 1.00 27.76 C +ATOM 3890 C ASN A 262 24.290 2.460 1.665 1.00 25.27 C +ATOM 3891 O ASN A 262 24.167 1.239 1.685 1.00 25.48 O +ATOM 3892 CB ASN A 262 23.073 3.000 -0.463 1.00 28.70 C +ATOM 3893 CG ASN A 262 23.064 3.717 -1.813 1.00 33.27 C +ATOM 3894 OD1 ASN A 262 23.089 4.945 -1.868 1.00 35.47 O +ATOM 3895 ND2 ASN A 262 23.018 2.949 -2.903 1.00 30.78 N +ATOM 3896 H ASN A 262 25.441 1.753 -0.799 1.00 30.06 H +ATOM 3897 HA ASN A 262 24.491 4.266 0.533 1.00 27.76 H +ATOM 3898 HB3 ASN A 262 22.231 3.384 0.114 1.00 28.70 H +ATOM 3899 HB2 ASN A 262 22.878 1.940 -0.607 1.00 28.70 H +ATOM 3900 HD22 ASN A 262 22.995 3.360 -3.824 1.00 30.78 H +ATOM 3901 HD21 ASN A 262 23.005 1.940 -2.812 1.00 30.78 H +ATOM 3902 N LEU A 263 24.334 3.219 2.762 1.00 25.22 N +ATOM 3903 CA LEU A 263 24.276 2.707 4.124 1.00 25.09 C +ATOM 3904 C LEU A 263 22.918 3.140 4.677 1.00 22.26 C +ATOM 3905 O LEU A 263 22.766 4.266 5.153 1.00 22.01 O +ATOM 3906 CB LEU A 263 25.496 3.239 4.911 1.00 27.62 C +ATOM 3907 CG LEU A 263 26.846 2.806 4.287 1.00 30.92 C +ATOM 3908 CD1 LEU A 263 28.031 3.570 4.886 1.00 34.54 C +ATOM 3909 CD2 LEU A 263 27.074 1.283 4.334 1.00 30.34 C +ATOM 3910 H LEU A 263 24.449 4.222 2.678 1.00 25.22 H +ATOM 3911 HA LEU A 263 24.313 1.617 4.137 1.00 25.09 H +ATOM 3912 HB3 LEU A 263 25.446 2.904 5.948 1.00 27.62 H +ATOM 3913 HB2 LEU A 263 25.458 4.327 4.950 1.00 27.62 H +ATOM 3914 HG LEU A 263 26.841 3.099 3.238 1.00 30.92 H +ATOM 3915 HD11 LEU A 263 28.952 3.354 4.345 1.00 34.54 H +ATOM 3916 HD12 LEU A 263 27.874 4.646 4.822 1.00 34.54 H +ATOM 3917 HD13 LEU A 263 28.191 3.299 5.928 1.00 34.54 H +ATOM 3918 HD21 LEU A 263 28.055 1.027 4.732 1.00 30.34 H +ATOM 3919 HD22 LEU A 263 26.334 0.773 4.945 1.00 30.34 H +ATOM 3920 HD23 LEU A 263 27.009 0.849 3.337 1.00 30.34 H +ATOM 3921 N VAL A 264 21.940 2.242 4.499 1.00 21.33 N +ATOM 3922 CA VAL A 264 20.529 2.499 4.732 1.00 21.12 C +ATOM 3923 C VAL A 264 20.145 1.974 6.121 1.00 20.78 C +ATOM 3924 O VAL A 264 20.395 0.811 6.423 1.00 22.61 O +ATOM 3925 CB VAL A 264 19.640 1.807 3.661 1.00 22.88 C +ATOM 3926 CG1 VAL A 264 18.133 2.074 3.863 1.00 19.18 C +ATOM 3927 CG2 VAL A 264 20.061 2.208 2.236 1.00 19.56 C +ATOM 3928 H VAL A 264 22.165 1.325 4.132 1.00 21.33 H +ATOM 3929 HA VAL A 264 20.354 3.570 4.673 1.00 21.12 H +ATOM 3930 HB VAL A 264 19.789 0.730 3.725 1.00 22.88 H +ATOM 3931 HG11 VAL A 264 17.544 1.672 3.041 1.00 19.18 H +ATOM 3932 HG12 VAL A 264 17.761 1.613 4.777 1.00 19.18 H +ATOM 3933 HG13 VAL A 264 17.925 3.143 3.922 1.00 19.18 H +ATOM 3934 HG21 VAL A 264 19.474 1.677 1.491 1.00 19.56 H +ATOM 3935 HG22 VAL A 264 19.939 3.276 2.069 1.00 19.56 H +ATOM 3936 HG23 VAL A 264 21.104 1.960 2.036 1.00 19.56 H +ATOM 3937 N ASP A 265 19.531 2.845 6.926 1.00 21.91 N +ATOM 3938 CA ASP A 265 19.002 2.547 8.249 1.00 22.53 C +ATOM 3939 C ASP A 265 17.505 2.839 8.163 1.00 21.18 C +ATOM 3940 O ASP A 265 17.105 3.999 8.094 1.00 19.87 O +ATOM 3941 CB ASP A 265 19.778 3.337 9.328 1.00 23.03 C +ATOM 3942 CG ASP A 265 19.279 3.361 10.784 1.00 26.46 C +ATOM 3943 OD1 ASP A 265 18.330 2.628 11.137 1.00 25.06 O +ATOM 3944 OD2 ASP A 265 19.921 4.108 11.553 1.00 29.68 O1- +ATOM 3945 H ASP A 265 19.354 3.784 6.589 1.00 21.91 H +ATOM 3946 HA ASP A 265 19.118 1.487 8.475 1.00 22.53 H +ATOM 3947 HB3 ASP A 265 19.882 4.365 8.991 1.00 23.03 H +ATOM 3948 HB2 ASP A 265 20.793 2.940 9.350 1.00 23.03 H +ATOM 3949 N LEU A 266 16.721 1.757 8.122 1.00 19.19 N +ATOM 3950 CA LEU A 266 15.273 1.789 7.967 1.00 20.84 C +ATOM 3951 C LEU A 266 14.579 2.204 9.268 1.00 20.61 C +ATOM 3952 O LEU A 266 15.143 2.039 10.350 1.00 20.90 O +ATOM 3953 CB LEU A 266 14.803 0.386 7.531 1.00 17.59 C +ATOM 3954 CG LEU A 266 15.381 -0.068 6.173 1.00 21.63 C +ATOM 3955 CD1 LEU A 266 15.095 -1.554 5.947 1.00 18.98 C +ATOM 3956 CD2 LEU A 266 14.833 0.777 5.013 1.00 19.35 C +ATOM 3957 H LEU A 266 17.135 0.839 8.215 1.00 19.19 H +ATOM 3958 HA LEU A 266 15.020 2.519 7.196 1.00 20.84 H +ATOM 3959 HB3 LEU A 266 13.713 0.353 7.484 1.00 17.59 H +ATOM 3960 HB2 LEU A 266 15.084 -0.335 8.301 1.00 17.59 H +ATOM 3961 HG LEU A 266 16.466 0.035 6.182 1.00 21.63 H +ATOM 3962 HD11 LEU A 266 15.381 -1.883 4.949 1.00 18.98 H +ATOM 3963 HD12 LEU A 266 15.647 -2.165 6.661 1.00 18.98 H +ATOM 3964 HD13 LEU A 266 14.032 -1.752 6.071 1.00 18.98 H +ATOM 3965 HD21 LEU A 266 14.946 0.276 4.052 1.00 19.35 H +ATOM 3966 HD22 LEU A 266 13.773 0.980 5.155 1.00 19.35 H +ATOM 3967 HD23 LEU A 266 15.349 1.734 4.940 1.00 19.35 H +ATOM 3968 N ALA A 267 13.331 2.675 9.129 1.00 21.47 N +ATOM 3969 CA ALA A 267 12.390 2.869 10.230 1.00 19.08 C +ATOM 3970 C ALA A 267 12.118 1.549 10.960 1.00 19.61 C +ATOM 3971 O ALA A 267 12.099 0.499 10.316 1.00 18.68 O +ATOM 3972 CB ALA A 267 11.079 3.422 9.666 1.00 18.56 C +ATOM 3973 H ALA A 267 12.955 2.799 8.198 1.00 21.47 H +ATOM 3974 HA ALA A 267 12.812 3.596 10.924 1.00 19.08 H +ATOM 3975 HB1 ALA A 267 10.395 3.692 10.470 1.00 18.56 H +ATOM 3976 HB2 ALA A 267 11.258 4.314 9.066 1.00 18.56 H +ATOM 3977 HB3 ALA A 267 10.573 2.692 9.033 1.00 18.56 H +ATOM 3978 N GLY A 268 11.906 1.640 12.281 1.00 20.90 N +ATOM 3979 CA GLY A 268 11.627 0.527 13.183 1.00 21.41 C +ATOM 3980 C GLY A 268 10.481 -0.354 12.668 1.00 22.97 C +ATOM 3981 O GLY A 268 9.420 0.151 12.303 1.00 21.66 O +ATOM 3982 H GLY A 268 11.923 2.560 12.704 1.00 20.90 H +ATOM 3983 HA3 GLY A 268 11.344 0.954 14.142 1.00 21.41 H +ATOM 3984 HA2 GLY A 268 12.535 -0.057 13.338 1.00 21.41 H +ATOM 3985 N SER A 269 10.715 -1.674 12.655 1.00 23.42 N +ATOM 3986 CA SER A 269 9.807 -2.677 12.104 1.00 24.42 C +ATOM 3987 C SER A 269 8.610 -3.066 12.996 1.00 27.82 C +ATOM 3988 O SER A 269 7.819 -3.892 12.540 1.00 27.45 O +ATOM 3989 CB SER A 269 10.635 -3.908 11.686 1.00 22.75 C +ATOM 3990 OG SER A 269 11.128 -4.632 12.793 1.00 25.27 O +ATOM 3991 H SER A 269 11.603 -2.028 12.986 1.00 23.42 H +ATOM 3992 HA SER A 269 9.382 -2.263 11.189 1.00 24.42 H +ATOM 3993 HB3 SER A 269 11.466 -3.623 11.043 1.00 22.75 H +ATOM 3994 HB2 SER A 269 10.007 -4.583 11.110 1.00 22.75 H +ATOM 3995 HG SER A 269 11.645 -5.375 12.469 1.00 25.27 H +ATOM 3996 N GLU A 270 8.484 -2.509 14.219 1.00 30.78 N +ATOM 3997 CA GLU A 270 7.446 -2.890 15.187 1.00 34.86 C +ATOM 3998 C GLU A 270 6.014 -2.668 14.677 1.00 37.87 C +ATOM 3999 O GLU A 270 5.767 -1.746 13.900 1.00 37.82 O +ATOM 4000 CB GLU A 270 7.677 -2.271 16.597 1.00 34.89 C +ATOM 4001 CG GLU A 270 7.064 -0.883 16.938 1.00 37.74 C +ATOM 4002 CD GLU A 270 7.750 0.331 16.298 1.00 43.02 C +ATOM 4003 OE1 GLU A 270 8.632 0.912 16.971 1.00 35.23 O +ATOM 4004 OE2 GLU A 270 7.397 0.674 15.149 1.00 47.66 O1- +ATOM 4005 H GLU A 270 9.168 -1.834 14.538 1.00 30.78 H +ATOM 4006 HA GLU A 270 7.586 -3.959 15.296 1.00 34.86 H +ATOM 4007 HB3 GLU A 270 8.734 -2.288 16.849 1.00 34.89 H +ATOM 4008 HB2 GLU A 270 7.248 -2.972 17.314 1.00 34.89 H +ATOM 4009 HG3 GLU A 270 7.103 -0.757 18.022 1.00 37.74 H +ATOM 4010 HG2 GLU A 270 6.000 -0.854 16.705 1.00 37.74 H +ATOM 4011 N ASN A 271 5.093 -3.516 15.160 1.00 41.83 N +ATOM 4012 CA ASN A 271 3.653 -3.420 14.910 1.00 44.48 C +ATOM 4013 C ASN A 271 3.085 -2.097 15.443 1.00 45.67 C +ATOM 4014 O ASN A 271 3.433 -1.684 16.551 1.00 46.37 O +ATOM 4015 CB ASN A 271 2.931 -4.602 15.597 1.00 47.15 C +ATOM 4016 CG ASN A 271 3.222 -5.969 14.971 1.00 50.68 C +ATOM 4017 OD1 ASN A 271 3.251 -6.109 13.750 1.00 51.46 O +ATOM 4018 ND2 ASN A 271 3.409 -6.993 15.806 1.00 52.35 N +ATOM 4019 H ASN A 271 5.382 -4.244 15.803 1.00 41.83 H +ATOM 4020 HA ASN A 271 3.521 -3.479 13.828 1.00 44.48 H +ATOM 4021 HB3 ASN A 271 1.851 -4.459 15.531 1.00 47.15 H +ATOM 4022 HB2 ASN A 271 3.170 -4.622 16.663 1.00 47.15 H +ATOM 4023 HD22 ASN A 271 3.582 -7.920 15.447 1.00 52.35 H +ATOM 4024 HD21 ASN A 271 3.401 -6.849 16.806 1.00 52.35 H +ATOM 4025 N ILE A 272 2.195 -1.486 14.649 1.00 13.83 N +ATOM 4026 CA ILE A 272 1.460 -0.288 15.034 1.00 15.42 C +ATOM 4027 C ILE A 272 0.055 -0.677 15.526 1.00 16.71 C +ATOM 4028 O ILE A 272 -0.660 -1.417 14.847 1.00 17.84 O +ATOM 4029 CB ILE A 272 1.359 0.732 13.855 1.00 0.00 C +ATOM 4030 CG1 ILE A 272 0.739 2.089 14.265 1.00 0.00 C +ATOM 4031 CG2 ILE A 272 0.636 0.199 12.597 1.00 0.00 C +ATOM 4032 CD1 ILE A 272 1.489 2.818 15.390 1.00 0.00 C +ATOM 4033 HB ILE A 272 2.385 0.939 13.546 1.00 0.00 H +ATOM 4034 HG12 ILE A 272 0.710 2.745 13.399 1.00 0.00 H +ATOM 4035 HG13 ILE A 272 -0.305 1.958 14.546 1.00 0.00 H +ATOM 4036 HG21 ILE A 272 0.745 0.894 11.765 1.00 0.00 H +ATOM 4037 HG22 ILE A 272 1.045 -0.756 12.271 1.00 0.00 H +ATOM 4038 HG23 ILE A 272 -0.434 0.071 12.759 1.00 0.00 H +ATOM 4039 HD11 ILE A 272 1.318 3.893 15.335 1.00 0.00 H +ATOM 4040 HD12 ILE A 272 1.152 2.483 16.371 1.00 0.00 H +ATOM 4041 HD13 ILE A 272 2.565 2.652 15.328 1.00 0.00 H +ATOM 4042 H ILE A 272 1.951 -1.893 13.758 1.00 13.83 H +ATOM 4043 HA ILE A 272 1.988 0.206 15.852 1.00 15.42 H +ATOM 4044 N GLY A 273 -0.321 -0.123 16.688 1.00 17.08 N +ATOM 4045 CA GLY A 273 -1.707 -0.053 17.131 1.00 15.97 C +ATOM 4046 C GLY A 273 -2.224 1.274 16.576 1.00 17.17 C +ATOM 4047 O GLY A 273 -1.744 2.333 16.984 1.00 15.94 O +ATOM 4048 HA3 GLY A 273 -1.743 -0.038 18.221 1.00 15.97 H +ATOM 4049 H GLY A 273 0.342 0.445 17.196 1.00 17.08 H +ATOM 4050 HA2 GLY A 273 -2.303 -0.901 16.788 1.00 15.97 H +ATOM 4051 N ARG A 274 -3.170 1.206 15.626 1.00 14.58 N +ATOM 4052 CA ARG A 274 -3.710 2.361 14.904 1.00 15.78 C +ATOM 4053 C ARG A 274 -4.465 3.351 15.808 1.00 16.40 C +ATOM 4054 O ARG A 274 -4.947 2.978 16.879 1.00 14.34 O +ATOM 4055 CB ARG A 274 -4.683 1.882 13.807 1.00 0.00 C +ATOM 4056 CG ARG A 274 -4.110 0.939 12.736 1.00 0.00 C +ATOM 4057 CD ARG A 274 -5.173 0.730 11.646 1.00 0.00 C +ATOM 4058 NE ARG A 274 -4.850 -0.312 10.660 1.00 0.00 N +ATOM 4059 CZ ARG A 274 -5.648 -0.682 9.636 1.00 0.00 C +ATOM 4060 NH1 ARG A 274 -6.825 -0.080 9.392 1.00 0.00 N +ATOM 4061 NH2 ARG A 274 -5.258 -1.682 8.836 1.00 0.00 N1+ +ATOM 4062 HB2 ARG A 274 -5.538 1.392 14.279 1.00 0.00 H +ATOM 4063 HB3 ARG A 274 -5.095 2.753 13.294 1.00 0.00 H +ATOM 4064 HG2 ARG A 274 -3.252 1.449 12.296 1.00 0.00 H +ATOM 4065 HG3 ARG A 274 -3.741 -0.004 13.141 1.00 0.00 H +ATOM 4066 HD2 ARG A 274 -6.158 0.577 12.082 1.00 0.00 H +ATOM 4067 HD3 ARG A 274 -5.223 1.648 11.059 1.00 0.00 H +ATOM 4068 HE ARG A 274 -3.971 -0.791 10.791 1.00 0.00 H +ATOM 4069 HH12 ARG A 274 -7.416 -0.376 8.629 1.00 0.00 H +ATOM 4070 HH11 ARG A 274 -7.136 0.672 9.995 1.00 0.00 H +ATOM 4071 HH22 ARG A 274 -5.843 -1.982 8.070 1.00 0.00 H +ATOM 4072 HH21 ARG A 274 -4.378 -2.151 8.997 1.00 0.00 H +ATOM 4073 H ARG A 274 -3.523 0.303 15.343 1.00 14.58 H +ATOM 4074 HA ARG A 274 -2.875 2.886 14.435 1.00 15.78 H +ATOM 4075 N SER A 275 -4.634 4.577 15.287 1.00 14.55 N +ATOM 4076 CA SER A 275 -5.642 5.542 15.722 1.00 16.42 C +ATOM 4077 C SER A 275 -7.041 5.056 15.281 1.00 17.16 C +ATOM 4078 O SER A 275 -7.532 5.453 14.228 1.00 16.93 O +ATOM 4079 CB SER A 275 -5.237 6.937 15.190 1.00 0.00 C +ATOM 4080 OG SER A 275 -5.114 6.983 13.779 1.00 0.00 O +ATOM 4081 HB2 SER A 275 -5.971 7.682 15.497 1.00 0.00 H +ATOM 4082 HB3 SER A 275 -4.285 7.241 15.628 1.00 0.00 H +ATOM 4083 HG SER A 275 -4.912 7.884 13.516 1.00 0.00 H +ATOM 4084 H SER A 275 -4.195 4.801 14.406 1.00 14.55 H +ATOM 4085 HA SER A 275 -5.633 5.592 16.813 1.00 16.42 H +ATOM 4086 N GLY A 276 -7.623 4.142 16.081 1.00 15.23 N +ATOM 4087 CA GLY A 276 -8.789 3.319 15.736 1.00 16.84 C +ATOM 4088 C GLY A 276 -10.083 4.105 15.468 1.00 16.88 C +ATOM 4089 O GLY A 276 -10.978 3.576 14.811 1.00 16.65 O +ATOM 4090 HA3 GLY A 276 -8.971 2.619 16.551 1.00 16.84 H +ATOM 4091 H GLY A 276 -7.128 3.868 16.918 1.00 15.23 H +ATOM 4092 HA2 GLY A 276 -8.544 2.721 14.859 1.00 16.84 H +ATOM 4093 N ALA A 277 -10.172 5.363 15.934 0.50 17.32 N +ATOM 4094 CA ALA A 277 -11.259 6.295 15.628 0.50 21.27 C +ATOM 4095 C ALA A 277 -11.269 6.770 14.161 0.50 23.22 C +ATOM 4096 O ALA A 277 -12.330 7.156 13.670 0.50 25.56 O +ATOM 4097 CB ALA A 277 -11.154 7.497 16.578 1.00 0.00 C +ATOM 4098 HB1 ALA A 277 -10.208 8.027 16.450 1.00 0.00 H +ATOM 4099 HB2 ALA A 277 -11.960 8.211 16.405 1.00 0.00 H +ATOM 4100 HB3 ALA A 277 -11.219 7.180 17.619 1.00 0.00 H +ATOM 4101 H ALA A 277 -9.405 5.739 16.473 1.00 17.32 H +ATOM 4102 HA ALA A 277 -12.207 5.789 15.820 1.00 21.27 H +ATOM 4103 N VAL A 278 -10.101 6.733 13.496 1.00 20.27 N +ATOM 4104 CA VAL A 278 -9.903 7.185 12.120 1.00 20.59 C +ATOM 4105 C VAL A 278 -10.267 6.104 11.081 1.00 19.48 C +ATOM 4106 O VAL A 278 -10.578 6.480 9.959 1.00 18.81 O +ATOM 4107 CB VAL A 278 -8.430 7.644 11.878 1.00 0.00 C +ATOM 4108 CG1 VAL A 278 -8.113 8.110 10.438 1.00 0.00 C +ATOM 4109 CG2 VAL A 278 -8.026 8.757 12.863 1.00 0.00 C +ATOM 4110 HB VAL A 278 -7.772 6.797 12.070 1.00 0.00 H +ATOM 4111 HG11 VAL A 278 -7.115 8.546 10.376 1.00 0.00 H +ATOM 4112 HG12 VAL A 278 -8.127 7.286 9.725 1.00 0.00 H +ATOM 4113 HG13 VAL A 278 -8.823 8.865 10.099 1.00 0.00 H +ATOM 4114 HG21 VAL A 278 -7.001 9.086 12.691 1.00 0.00 H +ATOM 4115 HG22 VAL A 278 -8.675 9.628 12.764 1.00 0.00 H +ATOM 4116 HG23 VAL A 278 -8.078 8.418 13.898 1.00 0.00 H +ATOM 4117 H VAL A 278 -9.275 6.379 13.962 1.00 20.27 H +ATOM 4118 HA VAL A 278 -10.555 8.042 11.939 1.00 20.59 H +ATOM 4119 N ASP A 279 -10.264 4.806 11.440 1.00 16.88 N +ATOM 4120 CA ASP A 279 -10.481 3.666 10.523 1.00 15.78 C +ATOM 4121 C ASP A 279 -11.818 3.643 9.743 1.00 14.21 C +ATOM 4122 O ASP A 279 -11.919 2.900 8.766 1.00 16.58 O +ATOM 4123 CB ASP A 279 -10.245 2.299 11.216 1.00 0.00 C +ATOM 4124 CG ASP A 279 -8.841 2.072 11.805 1.00 0.00 C +ATOM 4125 OD1 ASP A 279 -7.871 2.700 11.324 1.00 0.00 O +ATOM 4126 OD2 ASP A 279 -8.731 1.143 12.633 1.00 0.00 O1- +ATOM 4127 HB2 ASP A 279 -10.970 2.182 12.023 1.00 0.00 H +ATOM 4128 HB3 ASP A 279 -10.425 1.486 10.511 1.00 0.00 H +ATOM 4129 H ASP A 279 -10.019 4.563 12.390 1.00 16.88 H +ATOM 4130 HA ASP A 279 -9.725 3.773 9.743 1.00 15.78 H +ATOM 4131 N LYS A 280 -12.794 4.471 10.148 1.00 16.18 N +ATOM 4132 CA LYS A 280 -14.050 4.729 9.437 1.00 16.76 C +ATOM 4133 C LYS A 280 -13.888 5.639 8.192 1.00 17.04 C +ATOM 4134 O LYS A 280 -14.762 5.619 7.326 1.00 18.73 O +ATOM 4135 CB LYS A 280 -15.038 5.302 10.477 1.00 0.00 C +ATOM 4136 CG LYS A 280 -16.442 5.659 9.960 1.00 0.00 C +ATOM 4137 CD LYS A 280 -17.382 6.064 11.102 1.00 0.00 C +ATOM 4138 CE LYS A 280 -18.753 6.540 10.598 1.00 0.00 C +ATOM 4139 NZ LYS A 280 -19.634 6.933 11.711 1.00 0.00 N1+ +ATOM 4140 HB2 LYS A 280 -15.144 4.572 11.282 1.00 0.00 H +ATOM 4141 HB3 LYS A 280 -14.601 6.190 10.937 1.00 0.00 H +ATOM 4142 HG2 LYS A 280 -16.378 6.486 9.251 1.00 0.00 H +ATOM 4143 HG3 LYS A 280 -16.862 4.813 9.415 1.00 0.00 H +ATOM 4144 HD2 LYS A 280 -17.511 5.214 11.775 1.00 0.00 H +ATOM 4145 HD3 LYS A 280 -16.910 6.852 11.692 1.00 0.00 H +ATOM 4146 HE2 LYS A 280 -18.633 7.395 9.930 1.00 0.00 H +ATOM 4147 HE3 LYS A 280 -19.240 5.750 10.025 1.00 0.00 H +ATOM 4148 HZ1 LYS A 280 -19.206 7.684 12.233 1.00 0.00 H +ATOM 4149 HZ2 LYS A 280 -20.523 7.243 11.345 1.00 0.00 H +ATOM 4150 HZ3 LYS A 280 -19.781 6.141 12.321 1.00 0.00 H +ATOM 4151 H LYS A 280 -12.628 5.043 10.963 1.00 16.18 H +ATOM 4152 HA LYS A 280 -14.444 3.773 9.089 1.00 16.76 H +ATOM 4153 N ARG A 281 -12.786 6.411 8.122 1.00 17.25 N +ATOM 4154 CA ARG A 281 -12.413 7.331 7.043 1.00 16.47 C +ATOM 4155 C ARG A 281 -12.039 6.565 5.763 1.00 18.22 C +ATOM 4156 O ARG A 281 -10.873 6.214 5.576 1.00 17.69 O +ATOM 4157 CB ARG A 281 -11.258 8.226 7.560 1.00 0.00 C +ATOM 4158 CG ARG A 281 -10.642 9.271 6.615 1.00 0.00 C +ATOM 4159 CD ARG A 281 -11.616 10.269 5.976 1.00 0.00 C +ATOM 4160 NE ARG A 281 -10.845 11.345 5.330 1.00 0.00 N +ATOM 4161 CZ ARG A 281 -11.113 12.659 5.250 1.00 0.00 C +ATOM 4162 NH1 ARG A 281 -12.265 13.188 5.688 1.00 0.00 N +ATOM 4163 NH2 ARG A 281 -10.180 13.461 4.721 1.00 0.00 N1+ +ATOM 4164 HB2 ARG A 281 -11.576 8.729 8.474 1.00 0.00 H +ATOM 4165 HB3 ARG A 281 -10.425 7.585 7.842 1.00 0.00 H +ATOM 4166 HG2 ARG A 281 -9.812 9.780 7.108 1.00 0.00 H +ATOM 4167 HG3 ARG A 281 -10.181 8.713 5.801 1.00 0.00 H +ATOM 4168 HD2 ARG A 281 -12.137 9.774 5.156 1.00 0.00 H +ATOM 4169 HD3 ARG A 281 -12.375 10.609 6.680 1.00 0.00 H +ATOM 4170 HE ARG A 281 -9.934 11.057 4.992 1.00 0.00 H +ATOM 4171 HH12 ARG A 281 -12.434 14.181 5.625 1.00 0.00 H +ATOM 4172 HH11 ARG A 281 -12.968 12.589 6.094 1.00 0.00 H +ATOM 4173 HH22 ARG A 281 -10.333 14.455 4.645 1.00 0.00 H +ATOM 4174 HH21 ARG A 281 -9.286 13.073 4.448 1.00 0.00 H +ATOM 4175 H ARG A 281 -12.107 6.343 8.871 1.00 17.25 H +ATOM 4176 HA ARG A 281 -13.272 7.970 6.829 1.00 16.47 H +ATOM 4177 N ALA A 282 -13.044 6.336 4.902 1.00 19.52 N +ATOM 4178 CA ALA A 282 -12.904 5.703 3.592 1.00 19.44 C +ATOM 4179 C ALA A 282 -12.391 6.711 2.545 1.00 21.06 C +ATOM 4180 O ALA A 282 -13.111 7.061 1.610 1.00 20.72 O +ATOM 4181 CB ALA A 282 -14.249 5.064 3.207 1.00 0.00 C +ATOM 4182 HB1 ALA A 282 -14.186 4.560 2.241 1.00 0.00 H +ATOM 4183 HB2 ALA A 282 -14.552 4.318 3.943 1.00 0.00 H +ATOM 4184 HB3 ALA A 282 -15.045 5.807 3.144 1.00 0.00 H +ATOM 4185 H ALA A 282 -13.979 6.626 5.152 1.00 19.52 H +ATOM 4186 HA ALA A 282 -12.169 4.899 3.663 1.00 19.44 H +ATOM 4187 N ARG A 283 -11.140 7.151 2.742 1.00 20.98 N +ATOM 4188 CA ARG A 283 -10.361 7.987 1.834 1.00 20.56 C +ATOM 4189 C ARG A 283 -8.867 7.890 2.193 1.00 19.71 C +ATOM 4190 O ARG A 283 -8.040 7.843 1.282 1.00 21.33 O +ATOM 4191 CB ARG A 283 -10.856 9.453 1.813 1.00 0.00 C +ATOM 4192 CG ARG A 283 -10.199 10.274 0.683 1.00 0.00 C +ATOM 4193 CD ARG A 283 -9.815 11.709 1.078 1.00 0.00 C +ATOM 4194 NE ARG A 283 -8.888 12.297 0.094 1.00 0.00 N +ATOM 4195 CZ ARG A 283 -7.556 12.092 0.021 1.00 0.00 C +ATOM 4196 NH1 ARG A 283 -6.885 11.364 0.927 1.00 0.00 N +ATOM 4197 NH2 ARG A 283 -6.874 12.631 -0.997 1.00 0.00 N1+ +ATOM 4198 HB2 ARG A 283 -11.939 9.492 1.689 1.00 0.00 H +ATOM 4199 HB3 ARG A 283 -10.655 9.907 2.783 1.00 0.00 H +ATOM 4200 HG2 ARG A 283 -9.369 9.760 0.198 1.00 0.00 H +ATOM 4201 HG3 ARG A 283 -10.960 10.342 -0.096 1.00 0.00 H +ATOM 4202 HD2 ARG A 283 -10.709 12.329 0.998 1.00 0.00 H +ATOM 4203 HD3 ARG A 283 -9.478 11.805 2.108 1.00 0.00 H +ATOM 4204 HE ARG A 283 -9.324 12.843 -0.635 1.00 0.00 H +ATOM 4205 HH12 ARG A 283 -5.892 11.211 0.838 1.00 0.00 H +ATOM 4206 HH11 ARG A 283 -7.368 10.987 1.736 1.00 0.00 H +ATOM 4207 HH22 ARG A 283 -5.877 12.491 -1.074 1.00 0.00 H +ATOM 4208 HH21 ARG A 283 -7.348 13.184 -1.696 1.00 0.00 H +ATOM 4209 H ARG A 283 -10.636 6.795 3.544 1.00 20.98 H +ATOM 4210 HA ARG A 283 -10.484 7.566 0.833 1.00 20.56 H +ATOM 4211 N GLU A 284 -8.548 7.823 3.499 1.00 21.43 N +ATOM 4212 CA GLU A 284 -7.213 7.479 3.995 1.00 20.61 C +ATOM 4213 C GLU A 284 -7.036 5.952 4.037 1.00 20.80 C +ATOM 4214 O GLU A 284 -8.017 5.212 4.134 1.00 19.82 O +ATOM 4215 CB GLU A 284 -6.952 8.120 5.382 1.00 0.00 C +ATOM 4216 CG GLU A 284 -6.329 9.535 5.334 1.00 0.00 C +ATOM 4217 CD GLU A 284 -7.333 10.675 5.127 1.00 0.00 C +ATOM 4218 OE1 GLU A 284 -7.797 10.851 3.979 1.00 0.00 O +ATOM 4219 OE2 GLU A 284 -7.623 11.375 6.120 1.00 0.00 O1- +ATOM 4220 HB2 GLU A 284 -7.878 8.149 5.958 1.00 0.00 H +ATOM 4221 HB3 GLU A 284 -6.286 7.484 5.967 1.00 0.00 H +ATOM 4222 HG2 GLU A 284 -5.798 9.707 6.272 1.00 0.00 H +ATOM 4223 HG3 GLU A 284 -5.561 9.586 4.560 1.00 0.00 H +ATOM 4224 H GLU A 284 -9.273 7.884 4.198 1.00 21.43 H +ATOM 4225 HA GLU A 284 -6.466 7.864 3.299 1.00 20.61 H +ATOM 4226 N ALA A 285 -5.769 5.522 3.946 1.00 20.97 N +ATOM 4227 CA ALA A 285 -5.365 4.119 3.890 1.00 20.77 C +ATOM 4228 C ALA A 285 -5.089 3.530 5.282 1.00 20.48 C +ATOM 4229 O ALA A 285 -4.831 4.271 6.233 1.00 20.59 O +ATOM 4230 CB ALA A 285 -4.108 4.031 3.009 1.00 0.00 C +ATOM 4231 HB1 ALA A 285 -4.330 4.338 1.986 1.00 0.00 H +ATOM 4232 HB2 ALA A 285 -3.312 4.677 3.378 1.00 0.00 H +ATOM 4233 HB3 ALA A 285 -3.717 3.014 2.964 1.00 0.00 H +ATOM 4234 H ALA A 285 -5.020 6.196 3.896 1.00 20.97 H +ATOM 4235 HA ALA A 285 -6.155 3.530 3.419 1.00 20.77 H +ATOM 4236 N GLY A 286 -5.105 2.187 5.350 1.00 19.09 N +ATOM 4237 CA GLY A 286 -4.703 1.409 6.521 1.00 17.64 C +ATOM 4238 C GLY A 286 -3.176 1.280 6.506 1.00 16.69 C +ATOM 4239 O GLY A 286 -2.641 0.267 6.055 1.00 15.61 O +ATOM 4240 HA3 GLY A 286 -5.159 0.420 6.467 1.00 17.64 H +ATOM 4241 H GLY A 286 -5.331 1.662 4.519 1.00 19.09 H +ATOM 4242 HA2 GLY A 286 -5.044 1.874 7.447 1.00 17.64 H +ATOM 4243 N ASN A 287 -2.496 2.330 6.985 1.00 18.01 N +ATOM 4244 CA ASN A 287 -1.044 2.496 6.983 1.00 16.78 C +ATOM 4245 C ASN A 287 -0.629 3.506 8.069 1.00 17.94 C +ATOM 4246 O ASN A 287 -1.492 4.106 8.711 1.00 15.20 O +ATOM 4247 CB ASN A 287 -0.543 2.912 5.561 1.00 0.00 C +ATOM 4248 CG ASN A 287 -0.861 4.337 5.074 1.00 0.00 C +ATOM 4249 OD1 ASN A 287 -1.742 5.020 5.591 1.00 0.00 O +ATOM 4250 ND2 ASN A 287 -0.134 4.792 4.051 1.00 0.00 N +ATOM 4251 HB2 ASN A 287 0.542 2.850 5.546 1.00 0.00 H +ATOM 4252 HB3 ASN A 287 -0.894 2.201 4.813 1.00 0.00 H +ATOM 4253 HD22 ASN A 287 -0.300 5.721 3.691 1.00 0.00 H +ATOM 4254 HD21 ASN A 287 0.570 4.212 3.614 1.00 0.00 H +ATOM 4255 H ASN A 287 -3.011 3.130 7.329 1.00 18.01 H +ATOM 4256 HA ASN A 287 -0.566 1.556 7.265 1.00 16.78 H +ATOM 4257 N ILE A 288 0.688 3.744 8.165 1.00 39.42 N +ATOM 4258 CA ILE A 288 1.245 5.043 8.559 1.00 36.53 C +ATOM 4259 C ILE A 288 2.668 5.256 8.016 1.00 31.50 C +ATOM 4260 O ILE A 288 3.021 6.407 7.762 1.00 34.96 O +ATOM 4261 CB ILE A 288 1.211 5.423 10.079 1.00 39.81 C +ATOM 4262 CG1 ILE A 288 1.167 4.244 11.074 1.00 41.18 C +ATOM 4263 CG2 ILE A 288 0.086 6.432 10.379 1.00 39.92 C +ATOM 4264 CD1 ILE A 288 2.422 3.361 11.081 1.00 43.90 C +ATOM 4265 HA ILE A 288 0.646 5.780 8.018 1.00 36.53 H +ATOM 4266 HB ILE A 288 2.123 5.971 10.324 1.00 39.81 H +ATOM 4267 HG13 ILE A 288 0.281 3.633 10.901 1.00 41.18 H +ATOM 4268 HG12 ILE A 288 1.044 4.649 12.079 1.00 41.18 H +ATOM 4269 HG21 ILE A 288 0.153 6.797 11.404 1.00 39.92 H +ATOM 4270 HG22 ILE A 288 0.150 7.302 9.725 1.00 39.92 H +ATOM 4271 HG23 ILE A 288 -0.903 5.995 10.257 1.00 39.92 H +ATOM 4272 HD11 ILE A 288 2.221 2.410 10.593 1.00 43.90 H +ATOM 4273 HD12 ILE A 288 3.265 3.831 10.576 1.00 43.90 H +ATOM 4274 HD13 ILE A 288 2.741 3.143 12.100 1.00 43.90 H +ATOM 4275 H ILE A 288 1.322 3.154 7.647 1.00 39.42 H +ATOM 4276 N ASN A 289 3.438 4.173 7.812 1.00 28.46 N +ATOM 4277 CA ASN A 289 4.759 4.223 7.193 1.00 23.85 C +ATOM 4278 C ASN A 289 4.670 3.513 5.837 1.00 21.26 C +ATOM 4279 O ASN A 289 4.866 2.300 5.758 1.00 18.44 O +ATOM 4280 CB ASN A 289 5.815 3.594 8.132 1.00 23.77 C +ATOM 4281 CG ASN A 289 7.244 4.043 7.803 1.00 25.10 C +ATOM 4282 OD1 ASN A 289 7.622 4.158 6.638 1.00 25.42 O +ATOM 4283 ND2 ASN A 289 8.049 4.290 8.836 1.00 14.33 N +ATOM 4284 H ASN A 289 3.106 3.252 8.066 1.00 28.46 H +ATOM 4285 HA ASN A 289 5.078 5.242 6.963 1.00 23.85 H +ATOM 4286 HB3 ASN A 289 5.754 2.506 8.161 1.00 23.77 H +ATOM 4287 HB2 ASN A 289 5.605 3.925 9.151 1.00 23.77 H +ATOM 4288 HD22 ASN A 289 8.997 4.605 8.686 1.00 14.33 H +ATOM 4289 HD21 ASN A 289 7.720 4.166 9.783 1.00 14.33 H +ATOM 4290 N GLN A 290 4.359 4.298 4.794 1.00 21.33 N +ATOM 4291 CA GLN A 290 4.189 3.826 3.424 1.00 21.12 C +ATOM 4292 C GLN A 290 5.474 3.227 2.823 1.00 19.80 C +ATOM 4293 O GLN A 290 5.379 2.219 2.126 1.00 17.84 O +ATOM 4294 CB GLN A 290 3.600 4.974 2.574 1.00 22.69 C +ATOM 4295 CG GLN A 290 3.310 4.652 1.092 1.00 21.91 C +ATOM 4296 CD GLN A 290 2.296 3.518 0.906 1.00 24.64 C +ATOM 4297 OE1 GLN A 290 1.446 3.284 1.764 1.00 22.56 O +ATOM 4298 NE2 GLN A 290 2.362 2.823 -0.229 1.00 26.54 N +ATOM 4299 H GLN A 290 4.231 5.292 4.940 1.00 21.33 H +ATOM 4300 HA GLN A 290 3.454 3.020 3.471 1.00 21.12 H +ATOM 4301 HB3 GLN A 290 4.270 5.828 2.626 1.00 22.69 H +ATOM 4302 HB2 GLN A 290 2.676 5.318 3.041 1.00 22.69 H +ATOM 4303 HG3 GLN A 290 4.236 4.407 0.570 1.00 21.91 H +ATOM 4304 HG2 GLN A 290 2.916 5.541 0.600 1.00 21.91 H +ATOM 4305 HE22 GLN A 290 1.714 2.070 -0.411 1.00 26.54 H +ATOM 4306 HE21 GLN A 290 3.058 3.058 -0.927 1.00 26.54 H +ATOM 4307 N SER A 291 6.640 3.814 3.142 1.00 19.05 N +ATOM 4308 CA SER A 291 7.958 3.328 2.729 1.00 20.94 C +ATOM 4309 C SER A 291 8.326 1.947 3.288 1.00 20.92 C +ATOM 4310 O SER A 291 8.857 1.126 2.540 1.00 21.32 O +ATOM 4311 CB SER A 291 9.036 4.383 3.048 1.00 20.43 C +ATOM 4312 OG SER A 291 9.212 5.251 1.948 1.00 20.74 O +ATOM 4313 H SER A 291 6.632 4.656 3.702 1.00 19.05 H +ATOM 4314 HA SER A 291 7.932 3.178 1.655 1.00 20.94 H +ATOM 4315 HB3 SER A 291 9.999 3.917 3.252 1.00 20.43 H +ATOM 4316 HB2 SER A 291 8.778 4.964 3.934 1.00 20.43 H +ATOM 4317 HG SER A 291 8.467 5.867 1.940 1.00 20.74 H +ATOM 4318 N LEU A 292 8.008 1.704 4.571 1.00 19.79 N +ATOM 4319 CA LEU A 292 8.260 0.428 5.240 1.00 20.51 C +ATOM 4320 C LEU A 292 7.312 -0.687 4.760 1.00 21.92 C +ATOM 4321 O LEU A 292 7.773 -1.810 4.557 1.00 19.80 O +ATOM 4322 CB LEU A 292 8.196 0.637 6.767 1.00 21.65 C +ATOM 4323 CG LEU A 292 8.647 -0.567 7.624 1.00 25.71 C +ATOM 4324 CD1 LEU A 292 10.086 -1.034 7.309 1.00 23.44 C +ATOM 4325 CD2 LEU A 292 8.463 -0.257 9.121 1.00 25.41 C +ATOM 4326 H LEU A 292 7.554 2.420 5.121 1.00 19.79 H +ATOM 4327 HA LEU A 292 9.276 0.128 4.976 1.00 20.51 H +ATOM 4328 HB3 LEU A 292 7.175 0.907 7.039 1.00 21.65 H +ATOM 4329 HB2 LEU A 292 8.807 1.498 7.038 1.00 21.65 H +ATOM 4330 HG LEU A 292 7.981 -1.402 7.403 1.00 25.71 H +ATOM 4331 HD11 LEU A 292 10.645 -1.305 8.205 1.00 23.44 H +ATOM 4332 HD12 LEU A 292 10.069 -1.916 6.668 1.00 23.44 H +ATOM 4333 HD13 LEU A 292 10.667 -0.271 6.793 1.00 23.44 H +ATOM 4334 HD21 LEU A 292 7.907 -1.056 9.612 1.00 25.41 H +ATOM 4335 HD22 LEU A 292 9.414 -0.151 9.641 1.00 25.41 H +ATOM 4336 HD23 LEU A 292 7.912 0.669 9.286 1.00 25.41 H +ATOM 4337 N LEU A 293 6.025 -0.350 4.553 1.00 20.92 N +ATOM 4338 CA LEU A 293 5.007 -1.251 4.004 1.00 22.29 C +ATOM 4339 C LEU A 293 5.330 -1.695 2.573 1.00 22.16 C +ATOM 4340 O LEU A 293 5.236 -2.887 2.282 1.00 23.04 O +ATOM 4341 CB LEU A 293 3.624 -0.569 4.031 1.00 21.25 C +ATOM 4342 CG LEU A 293 3.002 -0.458 5.436 1.00 24.69 C +ATOM 4343 CD1 LEU A 293 1.803 0.504 5.422 1.00 21.82 C +ATOM 4344 CD2 LEU A 293 2.644 -1.833 6.037 1.00 24.44 C +ATOM 4345 H LEU A 293 5.722 0.595 4.752 1.00 20.92 H +ATOM 4346 HA LEU A 293 4.983 -2.148 4.625 1.00 22.29 H +ATOM 4347 HB3 LEU A 293 2.923 -1.109 3.393 1.00 21.25 H +ATOM 4348 HB2 LEU A 293 3.719 0.424 3.588 1.00 21.25 H +ATOM 4349 HG LEU A 293 3.754 -0.014 6.087 1.00 24.69 H +ATOM 4350 HD11 LEU A 293 1.941 1.272 6.182 1.00 21.82 H +ATOM 4351 HD12 LEU A 293 1.690 1.012 4.464 1.00 21.82 H +ATOM 4352 HD13 LEU A 293 0.854 0.008 5.627 1.00 21.82 H +ATOM 4353 HD21 LEU A 293 1.641 -1.863 6.462 1.00 24.44 H +ATOM 4354 HD22 LEU A 293 2.699 -2.629 5.294 1.00 24.44 H +ATOM 4355 HD23 LEU A 293 3.335 -2.092 6.839 1.00 24.44 H +ATOM 4356 N THR A 294 5.724 -0.734 1.721 1.00 22.88 N +ATOM 4357 CA THR A 294 6.076 -0.982 0.326 1.00 21.29 C +ATOM 4358 C THR A 294 7.383 -1.775 0.168 1.00 22.41 C +ATOM 4359 O THR A 294 7.451 -2.590 -0.746 1.00 21.52 O +ATOM 4360 CB THR A 294 6.203 0.323 -0.492 1.00 20.03 C +ATOM 4361 OG1 THR A 294 5.003 1.058 -0.389 1.00 16.51 O +ATOM 4362 CG2 THR A 294 6.453 0.118 -1.993 1.00 20.26 C +ATOM 4363 H THR A 294 5.782 0.225 2.038 1.00 22.88 H +ATOM 4364 HA THR A 294 5.275 -1.577 -0.114 1.00 21.29 H +ATOM 4365 HB THR A 294 7.003 0.929 -0.067 1.00 20.03 H +ATOM 4366 HG1 THR A 294 4.942 1.413 0.505 1.00 16.51 H +ATOM 4367 HG21 THR A 294 6.440 1.066 -2.530 1.00 20.26 H +ATOM 4368 HG22 THR A 294 7.416 -0.345 -2.197 1.00 20.26 H +ATOM 4369 HG23 THR A 294 5.687 -0.524 -2.427 1.00 20.26 H +ATOM 4370 N LEU A 295 8.366 -1.583 1.069 1.00 23.24 N +ATOM 4371 CA LEU A 295 9.595 -2.382 1.122 1.00 22.73 C +ATOM 4372 C LEU A 295 9.312 -3.875 1.365 1.00 22.80 C +ATOM 4373 O LEU A 295 9.913 -4.710 0.692 1.00 22.35 O +ATOM 4374 CB LEU A 295 10.562 -1.789 2.174 1.00 22.23 C +ATOM 4375 CG LEU A 295 11.905 -2.541 2.346 1.00 25.11 C +ATOM 4376 CD1 LEU A 295 12.750 -2.545 1.057 1.00 20.75 C +ATOM 4377 CD2 LEU A 295 12.686 -2.005 3.558 1.00 21.13 C +ATOM 4378 H LEU A 295 8.254 -0.885 1.793 1.00 23.24 H +ATOM 4379 HA LEU A 295 10.072 -2.306 0.145 1.00 22.73 H +ATOM 4380 HB3 LEU A 295 10.050 -1.767 3.137 1.00 22.23 H +ATOM 4381 HB2 LEU A 295 10.769 -0.748 1.924 1.00 22.23 H +ATOM 4382 HG LEU A 295 11.692 -3.582 2.579 1.00 25.11 H +ATOM 4383 HD11 LEU A 295 13.813 -2.393 1.245 1.00 20.75 H +ATOM 4384 HD12 LEU A 295 12.653 -3.502 0.543 1.00 20.75 H +ATOM 4385 HD13 LEU A 295 12.433 -1.767 0.364 1.00 20.75 H +ATOM 4386 HD21 LEU A 295 12.902 -2.811 4.260 1.00 21.13 H +ATOM 4387 HD22 LEU A 295 13.636 -1.555 3.274 1.00 21.13 H +ATOM 4388 HD23 LEU A 295 12.129 -1.243 4.105 1.00 21.13 H +ATOM 4389 N GLY A 296 8.369 -4.172 2.276 1.00 23.61 N +ATOM 4390 CA GLY A 296 7.920 -5.530 2.575 1.00 22.93 C +ATOM 4391 C GLY A 296 7.180 -6.155 1.384 1.00 24.51 C +ATOM 4392 O GLY A 296 7.392 -7.331 1.104 1.00 24.67 O +ATOM 4393 H GLY A 296 7.924 -3.421 2.787 1.00 23.61 H +ATOM 4394 HA3 GLY A 296 7.254 -5.502 3.437 1.00 22.93 H +ATOM 4395 HA2 GLY A 296 8.774 -6.153 2.844 1.00 22.93 H +ATOM 4396 N ARG A 297 6.356 -5.370 0.667 1.00 23.60 N +ATOM 4397 CA ARG A 297 5.608 -5.798 -0.522 1.00 23.93 C +ATOM 4398 C ARG A 297 6.494 -5.977 -1.768 1.00 23.58 C +ATOM 4399 O ARG A 297 6.197 -6.857 -2.573 1.00 23.29 O +ATOM 4400 CB ARG A 297 4.473 -4.797 -0.798 1.00 24.98 C +ATOM 4401 CG ARG A 297 3.398 -4.782 0.303 1.00 23.29 C +ATOM 4402 CD ARG A 297 2.517 -3.531 0.221 1.00 25.05 C +ATOM 4403 NE ARG A 297 1.533 -3.471 1.316 1.00 23.01 N +ATOM 4404 CZ ARG A 297 0.821 -2.392 1.694 1.00 22.41 C +ATOM 4405 NH1 ARG A 297 0.936 -1.208 1.076 1.00 24.72 N +ATOM 4406 NH2 ARG A 297 -0.030 -2.499 2.721 1.00 19.41 N1+ +ATOM 4407 H ARG A 297 6.227 -4.408 0.949 1.00 23.60 H +ATOM 4408 HA ARG A 297 5.152 -6.765 -0.306 1.00 23.93 H +ATOM 4409 HB3 ARG A 297 3.985 -5.040 -1.743 1.00 24.98 H +ATOM 4410 HB2 ARG A 297 4.898 -3.801 -0.929 1.00 24.98 H +ATOM 4411 HG3 ARG A 297 3.835 -4.865 1.298 1.00 23.29 H +ATOM 4412 HG2 ARG A 297 2.780 -5.672 0.179 1.00 23.29 H +ATOM 4413 HD3 ARG A 297 1.963 -3.529 -0.718 1.00 25.05 H +ATOM 4414 HD2 ARG A 297 3.150 -2.646 0.230 1.00 25.05 H +ATOM 4415 HE ARG A 297 1.391 -4.336 1.817 1.00 23.01 H +ATOM 4416 HH12 ARG A 297 0.377 -0.413 1.363 1.00 24.72 H +ATOM 4417 HH11 ARG A 297 1.571 -1.105 0.292 1.00 24.72 H +ATOM 4418 HH22 ARG A 297 -0.572 -1.699 3.017 1.00 19.41 H +ATOM 4419 HH21 ARG A 297 -0.142 -3.378 3.206 1.00 19.41 H +ATOM 4420 N VAL A 298 7.569 -5.179 -1.896 1.00 24.92 N +ATOM 4421 CA VAL A 298 8.597 -5.324 -2.930 1.00 24.78 C +ATOM 4422 C VAL A 298 9.428 -6.600 -2.718 1.00 27.12 C +ATOM 4423 O VAL A 298 9.617 -7.341 -3.679 1.00 27.82 O +ATOM 4424 CB VAL A 298 9.517 -4.068 -3.026 1.00 23.28 C +ATOM 4425 CG1 VAL A 298 10.884 -4.277 -3.713 1.00 22.42 C +ATOM 4426 CG2 VAL A 298 8.779 -2.922 -3.738 1.00 24.57 C +ATOM 4427 H VAL A 298 7.723 -4.443 -1.219 1.00 24.92 H +ATOM 4428 HA VAL A 298 8.085 -5.436 -3.886 1.00 24.78 H +ATOM 4429 HB VAL A 298 9.728 -3.728 -2.011 1.00 23.28 H +ATOM 4430 HG11 VAL A 298 11.404 -3.329 -3.847 1.00 22.42 H +ATOM 4431 HG12 VAL A 298 11.547 -4.914 -3.126 1.00 22.42 H +ATOM 4432 HG13 VAL A 298 10.769 -4.725 -4.700 1.00 22.42 H +ATOM 4433 HG21 VAL A 298 9.370 -2.008 -3.739 1.00 24.57 H +ATOM 4434 HG22 VAL A 298 8.568 -3.176 -4.777 1.00 24.57 H +ATOM 4435 HG23 VAL A 298 7.827 -2.690 -3.264 1.00 24.57 H +ATOM 4436 N ILE A 299 9.844 -6.865 -1.466 1.00 27.82 N +ATOM 4437 CA ILE A 299 10.501 -8.110 -1.055 1.00 30.85 C +ATOM 4438 C ILE A 299 9.614 -9.347 -1.296 1.00 32.84 C +ATOM 4439 O ILE A 299 10.116 -10.335 -1.827 1.00 33.53 O +ATOM 4440 CB ILE A 299 10.977 -8.048 0.432 1.00 28.95 C +ATOM 4441 CG1 ILE A 299 12.201 -7.106 0.550 1.00 27.94 C +ATOM 4442 CG2 ILE A 299 11.256 -9.415 1.115 1.00 27.72 C +ATOM 4443 CD1 ILE A 299 12.596 -6.762 1.990 1.00 30.35 C +ATOM 4444 H ILE A 299 9.659 -6.198 -0.728 1.00 27.82 H +ATOM 4445 HA ILE A 299 11.384 -8.225 -1.688 1.00 30.85 H +ATOM 4446 HB ILE A 299 10.172 -7.583 1.004 1.00 28.95 H +ATOM 4447 HG13 ILE A 299 12.011 -6.176 0.014 1.00 27.94 H +ATOM 4448 HG12 ILE A 299 13.063 -7.544 0.054 1.00 27.94 H +ATOM 4449 HG21 ILE A 299 11.655 -9.289 2.122 1.00 27.72 H +ATOM 4450 HG22 ILE A 299 10.348 -10.006 1.228 1.00 27.72 H +ATOM 4451 HG23 ILE A 299 11.971 -10.018 0.559 1.00 27.72 H +ATOM 4452 HD11 ILE A 299 12.945 -5.732 2.065 1.00 30.35 H +ATOM 4453 HD12 ILE A 299 11.750 -6.876 2.664 1.00 30.35 H +ATOM 4454 HD13 ILE A 299 13.397 -7.412 2.346 1.00 30.35 H +ATOM 4455 N THR A 300 8.315 -9.246 -0.964 1.00 33.27 N +ATOM 4456 CA THR A 300 7.307 -10.282 -1.203 1.00 34.38 C +ATOM 4457 C THR A 300 7.119 -10.599 -2.697 1.00 34.53 C +ATOM 4458 O THR A 300 7.111 -11.773 -3.058 1.00 38.06 O +ATOM 4459 CB THR A 300 5.925 -9.904 -0.600 1.00 33.97 C +ATOM 4460 OG1 THR A 300 6.051 -9.752 0.800 1.00 33.69 O +ATOM 4461 CG2 THR A 300 4.781 -10.901 -0.854 1.00 35.88 C +ATOM 4462 H THR A 300 7.983 -8.393 -0.533 1.00 33.27 H +ATOM 4463 HA THR A 300 7.659 -11.189 -0.715 1.00 34.38 H +ATOM 4464 HB THR A 300 5.617 -8.936 -0.994 1.00 33.97 H +ATOM 4465 HG1 THR A 300 6.568 -8.957 0.975 1.00 33.69 H +ATOM 4466 HG21 THR A 300 3.886 -10.623 -0.296 1.00 35.88 H +ATOM 4467 HG22 THR A 300 4.496 -10.933 -1.905 1.00 35.88 H +ATOM 4468 HG23 THR A 300 5.058 -11.909 -0.550 1.00 35.88 H +ATOM 4469 N ALA A 301 7.025 -9.554 -3.536 1.00 34.90 N +ATOM 4470 CA ALA A 301 6.903 -9.676 -4.986 1.00 35.29 C +ATOM 4471 C ALA A 301 8.136 -10.310 -5.653 1.00 36.92 C +ATOM 4472 O ALA A 301 7.967 -11.109 -6.572 1.00 36.87 O +ATOM 4473 CB ALA A 301 6.605 -8.299 -5.592 1.00 33.23 C +ATOM 4474 H ALA A 301 7.034 -8.612 -3.168 1.00 34.90 H +ATOM 4475 HA ALA A 301 6.048 -10.326 -5.182 1.00 35.29 H +ATOM 4476 HB1 ALA A 301 6.523 -8.362 -6.676 1.00 33.23 H +ATOM 4477 HB2 ALA A 301 5.663 -7.898 -5.217 1.00 33.23 H +ATOM 4478 HB3 ALA A 301 7.389 -7.578 -5.359 1.00 33.23 H +ATOM 4479 N LEU A 302 9.341 -9.972 -5.165 1.00 35.19 N +ATOM 4480 CA LEU A 302 10.617 -10.501 -5.649 1.00 36.10 C +ATOM 4481 C LEU A 302 10.817 -11.994 -5.333 1.00 37.90 C +ATOM 4482 O LEU A 302 11.231 -12.731 -6.229 1.00 38.70 O +ATOM 4483 CB LEU A 302 11.775 -9.653 -5.082 1.00 33.95 C +ATOM 4484 CG LEU A 302 11.927 -8.270 -5.752 1.00 33.02 C +ATOM 4485 CD1 LEU A 302 12.863 -7.367 -4.932 1.00 30.87 C +ATOM 4486 CD2 LEU A 302 12.384 -8.368 -7.219 1.00 32.24 C +ATOM 4487 H LEU A 302 9.397 -9.297 -4.413 1.00 35.19 H +ATOM 4488 HA LEU A 302 10.625 -10.408 -6.735 1.00 36.10 H +ATOM 4489 HB3 LEU A 302 12.720 -10.188 -5.189 1.00 33.95 H +ATOM 4490 HB2 LEU A 302 11.626 -9.535 -4.008 1.00 33.95 H +ATOM 4491 HG LEU A 302 10.952 -7.786 -5.759 1.00 33.02 H +ATOM 4492 HD11 LEU A 302 12.589 -6.320 -5.056 1.00 30.87 H +ATOM 4493 HD12 LEU A 302 12.821 -7.589 -3.866 1.00 30.87 H +ATOM 4494 HD13 LEU A 302 13.899 -7.481 -5.246 1.00 30.87 H +ATOM 4495 HD21 LEU A 302 13.063 -7.560 -7.487 1.00 32.24 H +ATOM 4496 HD22 LEU A 302 12.891 -9.310 -7.427 1.00 32.24 H +ATOM 4497 HD23 LEU A 302 11.531 -8.303 -7.893 1.00 32.24 H +ATOM 4498 N VAL A 303 10.523 -12.413 -4.089 1.00 38.90 N +ATOM 4499 CA VAL A 303 10.735 -13.791 -3.625 1.00 41.75 C +ATOM 4500 C VAL A 303 9.666 -14.775 -4.143 1.00 43.21 C +ATOM 4501 O VAL A 303 10.007 -15.927 -4.411 1.00 42.07 O +ATOM 4502 CB VAL A 303 10.807 -13.895 -2.074 1.00 41.73 C +ATOM 4503 CG1 VAL A 303 11.944 -13.029 -1.510 1.00 42.94 C +ATOM 4504 CG2 VAL A 303 9.489 -13.646 -1.318 1.00 45.02 C +ATOM 4505 H VAL A 303 10.190 -11.752 -3.399 1.00 38.90 H +ATOM 4506 HA VAL A 303 11.698 -14.128 -4.015 1.00 41.75 H +ATOM 4507 HB VAL A 303 11.085 -14.922 -1.831 1.00 41.73 H +ATOM 4508 HG11 VAL A 303 11.874 -12.941 -0.429 1.00 42.94 H +ATOM 4509 HG12 VAL A 303 12.917 -13.453 -1.757 1.00 42.94 H +ATOM 4510 HG13 VAL A 303 11.931 -12.017 -1.903 1.00 42.94 H +ATOM 4511 HG21 VAL A 303 9.646 -13.631 -0.239 1.00 45.02 H +ATOM 4512 HG22 VAL A 303 9.054 -12.694 -1.601 1.00 45.02 H +ATOM 4513 HG23 VAL A 303 8.753 -14.425 -1.514 1.00 45.02 H +ATOM 4514 N GLU A 304 8.419 -14.302 -4.321 1.00 45.70 N +ATOM 4515 CA GLU A 304 7.319 -15.062 -4.926 1.00 49.45 C +ATOM 4516 C GLU A 304 7.352 -15.055 -6.465 1.00 51.34 C +ATOM 4517 O GLU A 304 6.543 -15.753 -7.076 1.00 52.06 O +ATOM 4518 CB GLU A 304 5.968 -14.524 -4.409 1.00 49.94 C +ATOM 4519 CG GLU A 304 5.766 -14.754 -2.895 1.00 53.37 C +ATOM 4520 CD GLU A 304 4.437 -14.240 -2.318 1.00 56.10 C +ATOM 4521 OE1 GLU A 304 3.721 -13.481 -3.009 1.00 59.28 O +ATOM 4522 OE2 GLU A 304 4.166 -14.611 -1.154 1.00 56.03 O1- +ATOM 4523 H GLU A 304 8.204 -13.349 -4.058 1.00 45.70 H +ATOM 4524 HA GLU A 304 7.402 -16.106 -4.619 1.00 49.45 H +ATOM 4525 HB3 GLU A 304 5.148 -15.001 -4.949 1.00 49.94 H +ATOM 4526 HB2 GLU A 304 5.896 -13.460 -4.641 1.00 49.94 H +ATOM 4527 HG3 GLU A 304 6.568 -14.277 -2.334 1.00 53.37 H +ATOM 4528 HG2 GLU A 304 5.842 -15.822 -2.687 1.00 53.37 H +ATOM 4529 N ARG A 305 8.267 -14.269 -7.063 1.00 52.96 N +ATOM 4530 CA ARG A 305 8.451 -14.085 -8.506 1.00 55.80 C +ATOM 4531 C ARG A 305 7.221 -13.496 -9.225 1.00 56.10 C +ATOM 4532 O ARG A 305 7.021 -13.758 -10.411 1.00 58.37 O +ATOM 4533 CB ARG A 305 8.973 -15.374 -9.180 1.00 56.75 C +ATOM 4534 CG ARG A 305 10.239 -15.954 -8.517 1.00 57.95 C +ATOM 4535 CD ARG A 305 11.136 -16.732 -9.495 1.00 60.70 C +ATOM 4536 NE ARG A 305 11.780 -15.824 -10.464 1.00 64.39 N +ATOM 4537 CZ ARG A 305 12.596 -16.142 -11.484 1.00 65.17 C +ATOM 4538 NH1 ARG A 305 12.973 -17.406 -11.728 1.00 65.84 N +ATOM 4539 NH2 ARG A 305 13.042 -15.161 -12.279 1.00 65.41 N1+ +ATOM 4540 H ARG A 305 8.893 -13.734 -6.478 1.00 52.96 H +ATOM 4541 HA ARG A 305 9.232 -13.330 -8.600 1.00 55.80 H +ATOM 4542 HB3 ARG A 305 9.176 -15.150 -10.228 1.00 56.75 H +ATOM 4543 HB2 ARG A 305 8.197 -16.141 -9.195 1.00 56.75 H +ATOM 4544 HG3 ARG A 305 10.010 -16.547 -7.630 1.00 57.95 H +ATOM 4545 HG2 ARG A 305 10.817 -15.106 -8.144 1.00 57.95 H +ATOM 4546 HD3 ARG A 305 10.501 -17.385 -10.095 1.00 60.70 H +ATOM 4547 HD2 ARG A 305 11.843 -17.377 -8.972 1.00 60.70 H +ATOM 4548 HE ARG A 305 11.549 -14.849 -10.341 1.00 64.39 H +ATOM 4549 HH12 ARG A 305 13.586 -17.624 -12.500 1.00 65.84 H +ATOM 4550 HH11 ARG A 305 12.642 -18.151 -11.133 1.00 65.84 H +ATOM 4551 HH22 ARG A 305 13.655 -15.370 -13.054 1.00 65.41 H +ATOM 4552 HH21 ARG A 305 12.766 -14.204 -12.115 1.00 65.41 H +ATOM 4553 N THR A 306 6.430 -12.696 -8.490 1.00 55.97 N +ATOM 4554 CA THR A 306 5.245 -11.991 -8.971 1.00 55.57 C +ATOM 4555 C THR A 306 5.644 -10.969 -10.065 1.00 54.94 C +ATOM 4556 O THR A 306 6.546 -10.170 -9.800 1.00 56.07 O +ATOM 4557 CB THR A 306 4.586 -11.200 -7.810 1.00 55.82 C +ATOM 4558 OG1 THR A 306 4.186 -12.106 -6.799 1.00 55.58 O +ATOM 4559 CG2 THR A 306 3.334 -10.393 -8.204 1.00 56.42 C +ATOM 4560 H THR A 306 6.702 -12.498 -7.537 1.00 55.97 H +ATOM 4561 HA THR A 306 4.537 -12.745 -9.307 1.00 55.57 H +ATOM 4562 HB THR A 306 5.313 -10.515 -7.373 1.00 55.82 H +ATOM 4563 HG1 THR A 306 4.963 -12.539 -6.437 1.00 55.58 H +ATOM 4564 HG21 THR A 306 2.893 -9.910 -7.331 1.00 56.42 H +ATOM 4565 HG22 THR A 306 3.556 -9.606 -8.922 1.00 56.42 H +ATOM 4566 HG23 THR A 306 2.573 -11.038 -8.645 1.00 56.42 H +ATOM 4567 N PRO A 307 5.012 -11.029 -11.265 1.00 54.81 N +ATOM 4568 CA PRO A 307 5.316 -10.129 -12.400 1.00 54.33 C +ATOM 4569 C PRO A 307 5.409 -8.623 -12.091 1.00 52.41 C +ATOM 4570 O PRO A 307 6.333 -7.975 -12.581 1.00 53.53 O +ATOM 4571 CB PRO A 307 4.195 -10.423 -13.411 1.00 54.49 C +ATOM 4572 CG PRO A 307 3.832 -11.872 -13.152 1.00 55.69 C +ATOM 4573 CD PRO A 307 3.988 -12.008 -11.644 1.00 55.25 C +ATOM 4574 HA PRO A 307 6.269 -10.462 -12.816 1.00 54.33 H +ATOM 4575 HB3 PRO A 307 4.505 -10.254 -14.442 1.00 54.49 H +ATOM 4576 HB2 PRO A 307 3.323 -9.794 -13.221 1.00 54.49 H +ATOM 4577 HG3 PRO A 307 4.559 -12.515 -13.650 1.00 55.69 H +ATOM 4578 HG2 PRO A 307 2.840 -12.145 -13.513 1.00 55.69 H +ATOM 4579 HD2 PRO A 307 3.055 -11.761 -11.136 1.00 55.25 H +ATOM 4580 HD3 PRO A 307 4.261 -13.035 -11.403 1.00 55.25 H +ATOM 4581 N HIS A 308 4.480 -8.115 -11.264 1.00 49.84 N +ATOM 4582 CA HIS A 308 4.475 -6.737 -10.785 1.00 47.05 C +ATOM 4583 C HIS A 308 5.226 -6.639 -9.449 1.00 44.45 C +ATOM 4584 O HIS A 308 4.877 -7.347 -8.504 1.00 44.53 O +ATOM 4585 CB HIS A 308 3.017 -6.256 -10.651 1.00 48.81 C +ATOM 4586 CG HIS A 308 2.866 -4.820 -10.204 1.00 50.00 C +ATOM 4587 ND1 HIS A 308 3.509 -3.758 -10.852 1.00 49.02 N +ATOM 4588 CD2 HIS A 308 2.134 -4.318 -9.148 1.00 51.40 C +ATOM 4589 CE1 HIS A 308 3.149 -2.677 -10.172 1.00 50.89 C +ATOM 4590 NE2 HIS A 308 2.335 -2.949 -9.151 1.00 51.97 N +ATOM 4591 H HIS A 308 3.760 -8.716 -10.891 1.00 49.84 H +ATOM 4592 HA HIS A 308 4.970 -6.097 -11.520 1.00 47.05 H +ATOM 4593 HB3 HIS A 308 2.471 -6.894 -9.955 1.00 48.81 H +ATOM 4594 HB2 HIS A 308 2.511 -6.353 -11.612 1.00 48.81 H +ATOM 4595 HD2 HIS A 308 1.513 -4.808 -8.413 1.00 51.40 H +ATOM 4596 HE1 HIS A 308 3.485 -1.681 -10.418 1.00 50.89 H +ATOM 4597 HE2 HIS A 308 1.946 -2.282 -8.497 1.00 51.97 H +ATOM 4598 N VAL A 309 6.210 -5.730 -9.399 1.00 40.26 N +ATOM 4599 CA VAL A 309 6.958 -5.388 -8.193 1.00 35.27 C +ATOM 4600 C VAL A 309 6.672 -3.893 -7.912 1.00 31.25 C +ATOM 4601 O VAL A 309 7.007 -3.063 -8.761 1.00 30.60 O +ATOM 4602 CB VAL A 309 8.486 -5.578 -8.400 1.00 34.02 C +ATOM 4603 CG1 VAL A 309 9.287 -5.234 -7.127 1.00 31.38 C +ATOM 4604 CG2 VAL A 309 8.829 -7.015 -8.837 1.00 34.36 C +ATOM 4605 H VAL A 309 6.421 -5.179 -10.219 1.00 40.26 H +ATOM 4606 HA VAL A 309 6.664 -6.036 -7.372 1.00 35.27 H +ATOM 4607 HB VAL A 309 8.828 -4.920 -9.200 1.00 34.02 H +ATOM 4608 HG11 VAL A 309 10.335 -5.511 -7.234 1.00 31.38 H +ATOM 4609 HG12 VAL A 309 9.256 -4.169 -6.900 1.00 31.38 H +ATOM 4610 HG13 VAL A 309 8.902 -5.772 -6.261 1.00 31.38 H +ATOM 4611 HG21 VAL A 309 9.898 -7.121 -9.014 1.00 34.36 H +ATOM 4612 HG22 VAL A 309 8.543 -7.741 -8.076 1.00 34.36 H +ATOM 4613 HG23 VAL A 309 8.328 -7.291 -9.764 1.00 34.36 H +ATOM 4614 N PRO A 310 6.005 -3.573 -6.776 1.00 30.38 N +ATOM 4615 CA PRO A 310 5.485 -2.217 -6.504 1.00 29.30 C +ATOM 4616 C PRO A 310 6.547 -1.196 -6.030 1.00 28.73 C +ATOM 4617 O PRO A 310 6.369 -0.589 -4.976 1.00 27.93 O +ATOM 4618 CB PRO A 310 4.382 -2.493 -5.462 1.00 29.27 C +ATOM 4619 CG PRO A 310 4.892 -3.683 -4.673 1.00 29.44 C +ATOM 4620 CD PRO A 310 5.557 -4.524 -5.753 1.00 29.54 C +ATOM 4621 HA PRO A 310 5.019 -1.802 -7.400 1.00 29.30 H +ATOM 4622 HB3 PRO A 310 3.462 -2.770 -5.979 1.00 29.27 H +ATOM 4623 HB2 PRO A 310 4.139 -1.651 -4.814 1.00 29.27 H +ATOM 4624 HG3 PRO A 310 4.108 -4.216 -4.134 1.00 29.44 H +ATOM 4625 HG2 PRO A 310 5.635 -3.352 -3.947 1.00 29.44 H +ATOM 4626 HD2 PRO A 310 6.373 -5.115 -5.340 1.00 29.54 H +ATOM 4627 HD3 PRO A 310 4.826 -5.203 -6.196 1.00 29.54 H +ATOM 4628 N TYR A 311 7.620 -0.987 -6.819 1.00 28.68 N +ATOM 4629 CA TYR A 311 8.672 0.003 -6.543 1.00 29.45 C +ATOM 4630 C TYR A 311 8.145 1.442 -6.443 1.00 28.70 C +ATOM 4631 O TYR A 311 8.620 2.187 -5.594 1.00 24.95 O +ATOM 4632 CB TYR A 311 9.757 -0.010 -7.637 1.00 31.49 C +ATOM 4633 CG TYR A 311 10.513 -1.304 -7.844 1.00 34.07 C +ATOM 4634 CD1 TYR A 311 11.369 -1.804 -6.839 1.00 35.28 C +ATOM 4635 CD2 TYR A 311 10.416 -1.974 -9.080 1.00 36.40 C +ATOM 4636 CE1 TYR A 311 12.137 -2.959 -7.084 1.00 36.88 C +ATOM 4637 CE2 TYR A 311 11.189 -3.121 -9.326 1.00 39.34 C +ATOM 4638 CZ TYR A 311 12.055 -3.610 -8.332 1.00 38.02 C +ATOM 4639 OH TYR A 311 12.803 -4.719 -8.591 1.00 38.99 O +ATOM 4640 H TYR A 311 7.717 -1.523 -7.672 1.00 28.68 H +ATOM 4641 HA TYR A 311 9.129 -0.259 -5.588 1.00 29.45 H +ATOM 4642 HB3 TYR A 311 10.508 0.751 -7.414 1.00 31.49 H +ATOM 4643 HB2 TYR A 311 9.318 0.290 -8.591 1.00 31.49 H +ATOM 4644 HD1 TYR A 311 11.455 -1.293 -5.891 1.00 35.28 H +ATOM 4645 HD2 TYR A 311 9.767 -1.597 -9.857 1.00 36.40 H +ATOM 4646 HE1 TYR A 311 12.791 -3.336 -6.314 1.00 36.88 H +ATOM 4647 HE2 TYR A 311 11.118 -3.623 -10.280 1.00 39.34 H +ATOM 4648 HH TYR A 311 13.397 -4.944 -7.864 1.00 38.99 H +ATOM 4649 N ARG A 312 7.188 1.807 -7.311 1.00 28.58 N +ATOM 4650 CA ARG A 312 6.659 3.166 -7.431 1.00 28.46 C +ATOM 4651 C ARG A 312 5.696 3.596 -6.313 1.00 24.21 C +ATOM 4652 O ARG A 312 5.388 4.787 -6.238 1.00 25.31 O +ATOM 4653 CB ARG A 312 6.044 3.356 -8.827 1.00 35.11 C +ATOM 4654 CG ARG A 312 7.102 3.240 -9.934 1.00 41.09 C +ATOM 4655 CD ARG A 312 6.584 3.695 -11.308 1.00 45.95 C +ATOM 4656 NE ARG A 312 7.696 3.974 -12.232 1.00 49.55 N +ATOM 4657 CZ ARG A 312 8.467 5.079 -12.213 1.00 51.02 C +ATOM 4658 NH1 ARG A 312 8.266 6.062 -11.323 1.00 53.12 N +ATOM 4659 NH2 ARG A 312 9.460 5.204 -13.102 1.00 51.89 N1+ +ATOM 4660 H ARG A 312 6.829 1.128 -7.966 1.00 28.58 H +ATOM 4661 HA ARG A 312 7.497 3.854 -7.366 1.00 28.46 H +ATOM 4662 HB3 ARG A 312 5.599 4.351 -8.887 1.00 35.11 H +ATOM 4663 HB2 ARG A 312 5.231 2.647 -8.994 1.00 35.11 H +ATOM 4664 HG3 ARG A 312 7.356 2.182 -10.010 1.00 41.09 H +ATOM 4665 HG2 ARG A 312 8.031 3.744 -9.660 1.00 41.09 H +ATOM 4666 HD3 ARG A 312 5.854 4.503 -11.250 1.00 45.95 H +ATOM 4667 HD2 ARG A 312 6.065 2.852 -11.766 1.00 45.95 H +ATOM 4668 HE ARG A 312 7.905 3.251 -12.905 1.00 49.55 H +ATOM 4669 HH12 ARG A 312 8.822 6.911 -11.373 1.00 53.12 H +ATOM 4670 HH11 ARG A 312 7.512 5.999 -10.656 1.00 53.12 H +ATOM 4671 HH22 ARG A 312 10.008 6.053 -13.123 1.00 51.89 H +ATOM 4672 HH21 ARG A 312 9.644 4.480 -13.781 1.00 51.89 H +ATOM 4673 N GLU A 313 5.258 2.660 -5.455 1.00 23.86 N +ATOM 4674 CA GLU A 313 4.308 2.931 -4.375 1.00 23.27 C +ATOM 4675 C GLU A 313 4.916 3.625 -3.136 1.00 22.41 C +ATOM 4676 O GLU A 313 4.150 3.962 -2.235 1.00 20.21 O +ATOM 4677 CB GLU A 313 3.521 1.649 -4.026 1.00 23.76 C +ATOM 4678 CG GLU A 313 2.783 1.049 -5.251 1.00 28.94 C +ATOM 4679 CD GLU A 313 1.772 -0.074 -4.958 1.00 31.02 C +ATOM 4680 OE1 GLU A 313 1.386 -0.741 -5.943 1.00 28.97 O +ATOM 4681 OE2 GLU A 313 1.392 -0.263 -3.781 1.00 31.90 O1- +ATOM 4682 H GLU A 313 5.566 1.702 -5.551 1.00 23.86 H +ATOM 4683 HA GLU A 313 3.572 3.640 -4.760 1.00 23.27 H +ATOM 4684 HB3 GLU A 313 2.808 1.881 -3.234 1.00 23.76 H +ATOM 4685 HB2 GLU A 313 4.197 0.900 -3.617 1.00 23.76 H +ATOM 4686 HG3 GLU A 313 3.518 0.669 -5.963 1.00 28.94 H +ATOM 4687 HG2 GLU A 313 2.241 1.842 -5.767 1.00 28.94 H +ATOM 4688 N SER A 314 6.237 3.885 -3.112 1.00 21.60 N +ATOM 4689 CA SER A 314 6.876 4.691 -2.067 1.00 21.14 C +ATOM 4690 C SER A 314 8.168 5.363 -2.542 1.00 20.47 C +ATOM 4691 O SER A 314 8.789 4.903 -3.498 1.00 20.55 O +ATOM 4692 CB SER A 314 7.115 3.854 -0.795 1.00 20.33 C +ATOM 4693 OG SER A 314 8.272 3.039 -0.874 1.00 17.31 O +ATOM 4694 H SER A 314 6.828 3.597 -3.879 1.00 21.60 H +ATOM 4695 HA SER A 314 6.182 5.497 -1.822 1.00 21.14 H +ATOM 4696 HB3 SER A 314 6.244 3.259 -0.538 1.00 20.33 H +ATOM 4697 HB2 SER A 314 7.258 4.536 0.041 1.00 20.33 H +ATOM 4698 HG SER A 314 8.167 2.414 -1.599 1.00 17.31 H +ATOM 4699 N LYS A 315 8.568 6.408 -1.800 1.00 21.93 N +ATOM 4700 CA LYS A 315 9.823 7.142 -1.964 1.00 24.01 C +ATOM 4701 C LYS A 315 11.064 6.248 -1.788 1.00 23.64 C +ATOM 4702 O LYS A 315 11.952 6.307 -2.637 1.00 23.92 O +ATOM 4703 CB LYS A 315 9.868 8.328 -0.972 1.00 25.23 C +ATOM 4704 CG LYS A 315 8.738 9.365 -1.122 1.00 30.47 C +ATOM 4705 CD LYS A 315 8.782 10.164 -2.430 1.00 34.06 C +ATOM 4706 CE LYS A 315 7.603 11.137 -2.569 1.00 40.37 C +ATOM 4707 NZ LYS A 315 7.659 11.880 -3.839 1.00 44.85 N1+ +ATOM 4708 H LYS A 315 7.987 6.703 -1.024 1.00 21.93 H +ATOM 4709 HA LYS A 315 9.848 7.526 -2.985 1.00 24.01 H +ATOM 4710 HB3 LYS A 315 10.825 8.844 -1.059 1.00 25.23 H +ATOM 4711 HB2 LYS A 315 9.831 7.938 0.046 1.00 25.23 H +ATOM 4712 HG3 LYS A 315 8.799 10.059 -0.283 1.00 30.47 H +ATOM 4713 HG2 LYS A 315 7.768 8.880 -1.031 1.00 30.47 H +ATOM 4714 HD3 LYS A 315 8.796 9.486 -3.282 1.00 34.06 H +ATOM 4715 HD2 LYS A 315 9.714 10.729 -2.450 1.00 34.06 H +ATOM 4716 HE3 LYS A 315 7.605 11.853 -1.747 1.00 40.37 H +ATOM 4717 HE2 LYS A 315 6.658 10.593 -2.522 1.00 40.37 H +ATOM 4718 HZ1 LYS A 315 7.645 11.229 -4.610 1.00 44.85 H +ATOM 4719 HZ2 LYS A 315 6.864 12.499 -3.902 1.00 44.85 H +ATOM 4720 HZ3 LYS A 315 8.511 12.422 -3.871 1.00 44.85 H +ATOM 4721 N LEU A 316 11.089 5.425 -0.722 1.00 22.60 N +ATOM 4722 CA LEU A 316 12.199 4.528 -0.375 1.00 21.91 C +ATOM 4723 C LEU A 316 12.537 3.524 -1.485 1.00 21.21 C +ATOM 4724 O LEU A 316 13.696 3.436 -1.881 1.00 22.09 O +ATOM 4725 CB LEU A 316 11.882 3.800 0.951 1.00 22.01 C +ATOM 4726 CG LEU A 316 12.999 2.887 1.506 1.00 23.74 C +ATOM 4727 CD1 LEU A 316 14.245 3.698 1.908 1.00 23.65 C +ATOM 4728 CD2 LEU A 316 12.484 2.037 2.680 1.00 21.42 C +ATOM 4729 H LEU A 316 10.308 5.422 -0.079 1.00 22.60 H +ATOM 4730 HA LEU A 316 13.077 5.158 -0.226 1.00 21.91 H +ATOM 4731 HB3 LEU A 316 10.970 3.215 0.817 1.00 22.01 H +ATOM 4732 HB2 LEU A 316 11.655 4.540 1.715 1.00 22.01 H +ATOM 4733 HG LEU A 316 13.297 2.177 0.734 1.00 23.74 H +ATOM 4734 HD11 LEU A 316 14.887 3.140 2.591 1.00 23.65 H +ATOM 4735 HD12 LEU A 316 14.841 3.954 1.033 1.00 23.65 H +ATOM 4736 HD13 LEU A 316 13.975 4.631 2.402 1.00 23.65 H +ATOM 4737 HD21 LEU A 316 12.783 0.994 2.569 1.00 21.42 H +ATOM 4738 HD22 LEU A 316 12.876 2.398 3.628 1.00 21.42 H +ATOM 4739 HD23 LEU A 316 11.399 2.052 2.762 1.00 21.42 H +ATOM 4740 N THR A 317 11.516 2.793 -1.956 1.00 20.82 N +ATOM 4741 CA THR A 317 11.660 1.732 -2.951 1.00 21.01 C +ATOM 4742 C THR A 317 11.792 2.248 -4.401 1.00 22.51 C +ATOM 4743 O THR A 317 12.246 1.472 -5.239 1.00 24.89 O +ATOM 4744 CB THR A 317 10.476 0.741 -2.867 1.00 20.28 C +ATOM 4745 OG1 THR A 317 9.239 1.389 -3.069 1.00 19.26 O +ATOM 4746 CG2 THR A 317 10.406 0.013 -1.519 1.00 21.44 C +ATOM 4747 H THR A 317 10.584 2.932 -1.588 1.00 20.82 H +ATOM 4748 HA THR A 317 12.575 1.177 -2.728 1.00 21.01 H +ATOM 4749 HB THR A 317 10.586 -0.012 -3.648 1.00 20.28 H +ATOM 4750 HG1 THR A 317 9.195 1.713 -3.977 1.00 19.26 H +ATOM 4751 HG21 THR A 317 9.618 -0.737 -1.530 1.00 21.44 H +ATOM 4752 HG22 THR A 317 11.343 -0.503 -1.310 1.00 21.44 H +ATOM 4753 HG23 THR A 317 10.207 0.695 -0.691 1.00 21.44 H +ATOM 4754 N ARG A 318 11.474 3.530 -4.672 1.00 24.39 N +ATOM 4755 CA ARG A 318 11.843 4.211 -5.922 1.00 24.64 C +ATOM 4756 C ARG A 318 13.339 4.554 -5.939 1.00 24.75 C +ATOM 4757 O ARG A 318 14.006 4.280 -6.936 1.00 22.73 O +ATOM 4758 CB ARG A 318 11.035 5.513 -6.102 1.00 26.49 C +ATOM 4759 CG ARG A 318 9.578 5.282 -6.509 1.00 30.67 C +ATOM 4760 CD ARG A 318 8.700 6.540 -6.458 1.00 32.24 C +ATOM 4761 NE ARG A 318 9.039 7.522 -7.503 1.00 37.00 N +ATOM 4762 CZ ARG A 318 8.560 8.777 -7.606 1.00 39.39 C +ATOM 4763 NH1 ARG A 318 7.674 9.276 -6.730 1.00 42.30 N +ATOM 4764 NH2 ARG A 318 8.972 9.552 -8.616 1.00 40.43 N1+ +ATOM 4765 H ARG A 318 11.077 4.109 -3.945 1.00 24.39 H +ATOM 4766 HA ARG A 318 11.641 3.552 -6.769 1.00 24.64 H +ATOM 4767 HB3 ARG A 318 11.498 6.121 -6.881 1.00 26.49 H +ATOM 4768 HB2 ARG A 318 11.080 6.105 -5.188 1.00 26.49 H +ATOM 4769 HG3 ARG A 318 9.116 4.507 -5.913 1.00 30.67 H +ATOM 4770 HG2 ARG A 318 9.596 4.898 -7.530 1.00 30.67 H +ATOM 4771 HD3 ARG A 318 8.892 7.041 -5.508 1.00 32.24 H +ATOM 4772 HD2 ARG A 318 7.641 6.285 -6.461 1.00 32.24 H +ATOM 4773 HE ARG A 318 9.701 7.210 -8.198 1.00 37.00 H +ATOM 4774 HH12 ARG A 318 7.284 10.196 -6.868 1.00 42.30 H +ATOM 4775 HH11 ARG A 318 7.321 8.689 -5.984 1.00 42.30 H +ATOM 4776 HH22 ARG A 318 8.631 10.497 -8.713 1.00 40.43 H +ATOM 4777 HH21 ARG A 318 9.590 9.185 -9.332 1.00 40.43 H +ATOM 4778 N ILE A 319 13.825 5.147 -4.834 1.00 24.38 N +ATOM 4779 CA ILE A 319 15.213 5.573 -4.641 1.00 25.59 C +ATOM 4780 C ILE A 319 16.201 4.390 -4.594 1.00 25.42 C +ATOM 4781 O ILE A 319 17.299 4.508 -5.137 1.00 25.60 O +ATOM 4782 CB ILE A 319 15.347 6.455 -3.356 1.00 26.11 C +ATOM 4783 CG1 ILE A 319 14.636 7.814 -3.564 1.00 27.58 C +ATOM 4784 CG2 ILE A 319 16.790 6.700 -2.857 1.00 26.26 C +ATOM 4785 CD1 ILE A 319 14.237 8.535 -2.268 1.00 29.91 C +ATOM 4786 H ILE A 319 13.199 5.341 -4.064 1.00 24.38 H +ATOM 4787 HA ILE A 319 15.488 6.184 -5.503 1.00 25.59 H +ATOM 4788 HB ILE A 319 14.819 5.934 -2.555 1.00 26.11 H +ATOM 4789 HG13 ILE A 319 13.730 7.674 -4.148 1.00 27.58 H +ATOM 4790 HG12 ILE A 319 15.266 8.468 -4.166 1.00 27.58 H +ATOM 4791 HG21 ILE A 319 16.806 7.378 -2.004 1.00 26.26 H +ATOM 4792 HG22 ILE A 319 17.275 5.783 -2.526 1.00 26.26 H +ATOM 4793 HG23 ILE A 319 17.406 7.145 -3.639 1.00 26.26 H +ATOM 4794 HD11 ILE A 319 14.615 9.556 -2.268 1.00 29.91 H +ATOM 4795 HD12 ILE A 319 13.153 8.602 -2.178 1.00 29.91 H +ATOM 4796 HD13 ILE A 319 14.606 8.031 -1.374 1.00 29.91 H +ATOM 4797 N LEU A 320 15.774 3.273 -3.983 1.00 23.39 N +ATOM 4798 CA LEU A 320 16.553 2.046 -3.809 1.00 23.27 C +ATOM 4799 C LEU A 320 16.024 0.900 -4.693 1.00 22.23 C +ATOM 4800 O LEU A 320 16.201 -0.263 -4.328 1.00 18.72 O +ATOM 4801 CB LEU A 320 16.543 1.650 -2.312 1.00 23.58 C +ATOM 4802 CG LEU A 320 17.160 2.689 -1.352 1.00 25.87 C +ATOM 4803 CD1 LEU A 320 16.935 2.246 0.099 1.00 25.90 C +ATOM 4804 CD2 LEU A 320 18.655 2.952 -1.628 1.00 25.98 C +ATOM 4805 H LEU A 320 14.859 3.273 -3.551 1.00 23.39 H +ATOM 4806 HA LEU A 320 17.586 2.207 -4.119 1.00 23.27 H +ATOM 4807 HB3 LEU A 320 17.081 0.713 -2.168 1.00 23.58 H +ATOM 4808 HB2 LEU A 320 15.514 1.445 -2.012 1.00 23.58 H +ATOM 4809 HG LEU A 320 16.623 3.630 -1.471 1.00 25.87 H +ATOM 4810 HD11 LEU A 320 17.117 3.064 0.796 1.00 25.90 H +ATOM 4811 HD12 LEU A 320 15.916 1.893 0.258 1.00 25.90 H +ATOM 4812 HD13 LEU A 320 17.601 1.426 0.358 1.00 25.90 H +ATOM 4813 HD21 LEU A 320 19.249 2.942 -0.714 1.00 25.98 H +ATOM 4814 HD22 LEU A 320 19.087 2.205 -2.295 1.00 25.98 H +ATOM 4815 HD23 LEU A 320 18.799 3.927 -2.093 1.00 25.98 H +ATOM 4816 N GLN A 321 15.407 1.223 -5.846 1.00 21.93 N +ATOM 4817 CA GLN A 321 14.906 0.249 -6.824 1.00 25.12 C +ATOM 4818 C GLN A 321 15.974 -0.748 -7.309 1.00 23.77 C +ATOM 4819 O GLN A 321 15.700 -1.947 -7.354 1.00 25.82 O +ATOM 4820 CB GLN A 321 14.206 0.987 -7.991 1.00 25.91 C +ATOM 4821 CG GLN A 321 13.803 0.080 -9.178 1.00 35.95 C +ATOM 4822 CD GLN A 321 12.874 0.714 -10.217 1.00 39.40 C +ATOM 4823 OE1 GLN A 321 12.394 0.014 -11.104 1.00 43.71 O +ATOM 4824 NE2 GLN A 321 12.623 2.024 -10.141 1.00 41.83 N +ATOM 4825 H GLN A 321 15.287 2.197 -6.086 1.00 21.93 H +ATOM 4826 HA GLN A 321 14.142 -0.339 -6.310 1.00 25.12 H +ATOM 4827 HB3 GLN A 321 14.853 1.786 -8.357 1.00 25.91 H +ATOM 4828 HB2 GLN A 321 13.316 1.476 -7.595 1.00 25.91 H +ATOM 4829 HG3 GLN A 321 13.309 -0.815 -8.802 1.00 35.95 H +ATOM 4830 HG2 GLN A 321 14.693 -0.256 -9.712 1.00 35.95 H +ATOM 4831 HE22 GLN A 321 12.032 2.464 -10.830 1.00 41.83 H +ATOM 4832 HE21 GLN A 321 13.039 2.584 -9.411 1.00 41.83 H +ATOM 4833 N ASP A 322 17.174 -0.234 -7.626 1.00 25.83 N +ATOM 4834 CA ASP A 322 18.310 -1.015 -8.114 1.00 27.25 C +ATOM 4835 C ASP A 322 18.931 -1.931 -7.032 1.00 28.86 C +ATOM 4836 O ASP A 322 19.571 -2.922 -7.381 1.00 28.79 O +ATOM 4837 CB ASP A 322 19.382 -0.093 -8.743 1.00 28.99 C +ATOM 4838 CG ASP A 322 20.349 -0.795 -9.709 1.00 32.05 C +ATOM 4839 OD1 ASP A 322 19.857 -1.492 -10.624 1.00 27.75 O +ATOM 4840 OD2 ASP A 322 21.569 -0.580 -9.559 1.00 31.15 O1- +ATOM 4841 H ASP A 322 17.328 0.763 -7.538 1.00 25.83 H +ATOM 4842 HA ASP A 322 17.902 -1.664 -8.887 1.00 27.25 H +ATOM 4843 HB3 ASP A 322 19.936 0.416 -7.951 1.00 28.99 H +ATOM 4844 HB2 ASP A 322 18.893 0.709 -9.298 1.00 28.99 H +ATOM 4845 N SER A 323 18.711 -1.613 -5.746 1.00 28.11 N +ATOM 4846 CA SER A 323 19.153 -2.419 -4.602 1.00 26.92 C +ATOM 4847 C SER A 323 18.236 -3.628 -4.332 1.00 28.99 C +ATOM 4848 O SER A 323 18.616 -4.507 -3.563 1.00 30.38 O +ATOM 4849 CB SER A 323 19.220 -1.520 -3.354 1.00 24.83 C +ATOM 4850 OG SER A 323 20.107 -0.443 -3.569 1.00 25.15 O +ATOM 4851 H SER A 323 18.146 -0.804 -5.528 1.00 28.11 H +ATOM 4852 HA SER A 323 20.152 -2.810 -4.795 1.00 26.92 H +ATOM 4853 HB3 SER A 323 19.580 -2.087 -2.495 1.00 24.83 H +ATOM 4854 HB2 SER A 323 18.239 -1.134 -3.082 1.00 24.83 H +ATOM 4855 HG SER A 323 19.763 0.099 -4.283 1.00 25.15 H +ATOM 4856 N LEU A 324 17.047 -3.653 -4.948 1.00 28.47 N +ATOM 4857 CA LEU A 324 16.007 -4.642 -4.701 1.00 29.95 C +ATOM 4858 C LEU A 324 15.714 -5.360 -6.023 1.00 32.13 C +ATOM 4859 O LEU A 324 14.773 -4.995 -6.721 1.00 30.55 O +ATOM 4860 CB LEU A 324 14.776 -3.901 -4.127 1.00 26.21 C +ATOM 4861 CG LEU A 324 14.992 -3.285 -2.725 1.00 28.34 C +ATOM 4862 CD1 LEU A 324 13.824 -2.358 -2.345 1.00 24.74 C +ATOM 4863 CD2 LEU A 324 15.268 -4.347 -1.641 1.00 26.31 C +ATOM 4864 H LEU A 324 16.799 -2.905 -5.582 1.00 28.47 H +ATOM 4865 HA LEU A 324 16.330 -5.402 -3.987 1.00 29.95 H +ATOM 4866 HB3 LEU A 324 13.923 -4.579 -4.082 1.00 26.21 H +ATOM 4867 HB2 LEU A 324 14.495 -3.107 -4.820 1.00 26.21 H +ATOM 4868 HG LEU A 324 15.870 -2.640 -2.778 1.00 28.34 H +ATOM 4869 HD11 LEU A 324 14.170 -1.530 -1.725 1.00 24.74 H +ATOM 4870 HD12 LEU A 324 13.347 -1.919 -3.223 1.00 24.74 H +ATOM 4871 HD13 LEU A 324 13.049 -2.890 -1.795 1.00 24.74 H +ATOM 4872 HD21 LEU A 324 14.682 -4.177 -0.738 1.00 26.31 H +ATOM 4873 HD22 LEU A 324 15.038 -5.356 -1.986 1.00 26.31 H +ATOM 4874 HD23 LEU A 324 16.319 -4.334 -1.347 1.00 26.31 H +ATOM 4875 N GLY A 325 16.541 -6.365 -6.353 1.00 33.04 N +ATOM 4876 CA GLY A 325 16.398 -7.173 -7.566 1.00 35.57 C +ATOM 4877 C GLY A 325 17.047 -6.528 -8.804 1.00 36.92 C +ATOM 4878 O GLY A 325 16.805 -6.999 -9.916 1.00 37.76 O +ATOM 4879 H GLY A 325 17.297 -6.616 -5.731 1.00 33.04 H +ATOM 4880 HA3 GLY A 325 15.348 -7.383 -7.772 1.00 35.57 H +ATOM 4881 HA2 GLY A 325 16.874 -8.131 -7.383 1.00 35.57 H +ATOM 4882 N GLY A 326 17.848 -5.463 -8.629 1.00 36.99 N +ATOM 4883 CA GLY A 326 18.547 -4.767 -9.708 1.00 35.83 C +ATOM 4884 C GLY A 326 20.015 -5.204 -9.764 1.00 36.25 C +ATOM 4885 O GLY A 326 20.351 -6.339 -9.431 1.00 36.30 O +ATOM 4886 H GLY A 326 18.015 -5.127 -7.692 1.00 36.99 H +ATOM 4887 HA3 GLY A 326 18.475 -3.698 -9.542 1.00 35.83 H +ATOM 4888 HA2 GLY A 326 18.087 -4.949 -10.679 1.00 35.83 H +ATOM 4889 N ARG A 327 20.876 -4.291 -10.238 1.00 34.63 N +ATOM 4890 CA ARG A 327 22.294 -4.513 -10.534 1.00 36.55 C +ATOM 4891 C ARG A 327 23.259 -4.020 -9.437 1.00 36.94 C +ATOM 4892 O ARG A 327 24.462 -3.961 -9.692 1.00 38.93 O +ATOM 4893 CB ARG A 327 22.628 -3.865 -11.892 1.00 38.14 C +ATOM 4894 CG ARG A 327 21.859 -4.470 -13.075 1.00 42.41 C +ATOM 4895 CD ARG A 327 22.327 -3.867 -14.405 1.00 46.96 C +ATOM 4896 NE ARG A 327 21.543 -4.365 -15.547 1.00 51.13 N +ATOM 4897 CZ ARG A 327 21.654 -3.970 -16.830 1.00 54.30 C +ATOM 4898 NH1 ARG A 327 22.509 -3.008 -17.211 1.00 55.38 N +ATOM 4899 NH2 ARG A 327 20.886 -4.556 -17.757 1.00 54.29 N1+ +ATOM 4900 H ARG A 327 20.530 -3.364 -10.461 1.00 34.63 H +ATOM 4901 HA ARG A 327 22.468 -5.583 -10.626 1.00 36.55 H +ATOM 4902 HB3 ARG A 327 23.692 -3.980 -12.104 1.00 38.14 H +ATOM 4903 HB2 ARG A 327 22.442 -2.791 -11.843 1.00 38.14 H +ATOM 4904 HG3 ARG A 327 20.777 -4.393 -12.959 1.00 42.41 H +ATOM 4905 HG2 ARG A 327 22.092 -5.536 -13.080 1.00 42.41 H +ATOM 4906 HD3 ARG A 327 23.346 -4.210 -14.594 1.00 46.96 H +ATOM 4907 HD2 ARG A 327 22.365 -2.778 -14.361 1.00 46.96 H +ATOM 4908 HE ARG A 327 20.874 -5.088 -15.328 1.00 51.13 H +ATOM 4909 HH12 ARG A 327 22.580 -2.730 -18.179 1.00 55.38 H +ATOM 4910 HH11 ARG A 327 23.098 -2.558 -16.525 1.00 55.38 H +ATOM 4911 HH22 ARG A 327 20.956 -4.279 -18.726 1.00 54.29 H +ATOM 4912 HH21 ARG A 327 20.236 -5.284 -17.501 1.00 54.29 H +ATOM 4913 N THR A 328 22.747 -3.688 -8.245 1.00 34.16 N +ATOM 4914 CA THR A 328 23.559 -3.342 -7.077 1.00 31.72 C +ATOM 4915 C THR A 328 23.710 -4.595 -6.192 1.00 30.02 C +ATOM 4916 O THR A 328 22.729 -5.311 -5.995 1.00 30.34 O +ATOM 4917 CB THR A 328 22.844 -2.225 -6.270 1.00 31.13 C +ATOM 4918 OG1 THR A 328 22.993 -0.998 -6.956 1.00 32.46 O +ATOM 4919 CG2 THR A 328 23.300 -1.990 -4.826 1.00 28.96 C +ATOM 4920 H THR A 328 21.749 -3.742 -8.095 1.00 34.16 H +ATOM 4921 HA THR A 328 24.548 -2.990 -7.375 1.00 31.72 H +ATOM 4922 HB THR A 328 21.779 -2.434 -6.245 1.00 31.13 H +ATOM 4923 HG1 THR A 328 22.532 -1.051 -7.801 1.00 32.46 H +ATOM 4924 HG21 THR A 328 22.845 -1.086 -4.430 1.00 28.96 H +ATOM 4925 HG22 THR A 328 23.018 -2.808 -4.165 1.00 28.96 H +ATOM 4926 HG23 THR A 328 24.376 -1.865 -4.778 1.00 28.96 H +ATOM 4927 N ARG A 329 24.920 -4.825 -5.647 1.00 29.31 N +ATOM 4928 CA ARG A 329 25.159 -5.848 -4.622 1.00 29.30 C +ATOM 4929 C ARG A 329 24.519 -5.399 -3.301 1.00 26.80 C +ATOM 4930 O ARG A 329 24.894 -4.345 -2.795 1.00 29.25 O +ATOM 4931 CB ARG A 329 26.676 -6.102 -4.459 1.00 30.11 C +ATOM 4932 CG ARG A 329 27.028 -7.054 -3.295 1.00 31.58 C +ATOM 4933 CD ARG A 329 28.530 -7.319 -3.128 1.00 32.48 C +ATOM 4934 NE ARG A 329 28.805 -8.080 -1.897 1.00 36.20 N +ATOM 4935 CZ ARG A 329 29.960 -8.660 -1.517 1.00 37.53 C +ATOM 4936 NH1 ARG A 329 31.079 -8.578 -2.250 1.00 35.50 N +ATOM 4937 NH2 ARG A 329 29.991 -9.349 -0.370 1.00 37.85 N1+ +ATOM 4938 H ARG A 329 25.689 -4.196 -5.843 1.00 29.31 H +ATOM 4939 HA ARG A 329 24.692 -6.783 -4.941 1.00 29.30 H +ATOM 4940 HB3 ARG A 329 27.182 -5.151 -4.296 1.00 30.11 H +ATOM 4941 HB2 ARG A 329 27.075 -6.500 -5.392 1.00 30.11 H +ATOM 4942 HG3 ARG A 329 26.549 -8.003 -3.543 1.00 31.58 H +ATOM 4943 HG2 ARG A 329 26.599 -6.744 -2.344 1.00 31.58 H +ATOM 4944 HD3 ARG A 329 29.129 -6.411 -3.215 1.00 32.48 H +ATOM 4945 HD2 ARG A 329 28.828 -7.985 -3.937 1.00 32.48 H +ATOM 4946 HE ARG A 329 28.011 -8.160 -1.272 1.00 36.20 H +ATOM 4947 HH12 ARG A 329 31.942 -8.995 -1.935 1.00 35.50 H +ATOM 4948 HH11 ARG A 329 31.068 -8.087 -3.140 1.00 35.50 H +ATOM 4949 HH22 ARG A 329 30.850 -9.774 -0.052 1.00 37.85 H +ATOM 4950 HH21 ARG A 329 29.159 -9.437 0.200 1.00 37.85 H +ATOM 4951 N THR A 330 23.585 -6.195 -2.764 1.00 27.34 N +ATOM 4952 CA THR A 330 22.833 -5.805 -1.574 1.00 27.33 C +ATOM 4953 C THR A 330 22.998 -6.817 -0.436 1.00 28.41 C +ATOM 4954 O THR A 330 22.941 -8.026 -0.661 1.00 25.07 O +ATOM 4955 CB THR A 330 21.336 -5.609 -1.892 1.00 28.09 C +ATOM 4956 OG1 THR A 330 21.251 -4.518 -2.784 1.00 26.38 O +ATOM 4957 CG2 THR A 330 20.423 -5.299 -0.692 1.00 25.58 C +ATOM 4958 H THR A 330 23.317 -7.057 -3.217 1.00 27.34 H +ATOM 4959 HA THR A 330 23.184 -4.846 -1.209 1.00 27.33 H +ATOM 4960 HB THR A 330 20.953 -6.483 -2.414 1.00 28.09 H +ATOM 4961 HG1 THR A 330 20.321 -4.374 -2.990 1.00 26.38 H +ATOM 4962 HG21 THR A 330 19.409 -5.070 -1.018 1.00 25.58 H +ATOM 4963 HG22 THR A 330 20.346 -6.139 -0.003 1.00 25.58 H +ATOM 4964 HG23 THR A 330 20.795 -4.440 -0.132 1.00 25.58 H +ATOM 4965 N SER A 331 23.172 -6.258 0.770 1.00 29.22 N +ATOM 4966 CA SER A 331 23.208 -6.960 2.044 1.00 28.06 C +ATOM 4967 C SER A 331 22.117 -6.397 2.968 1.00 27.09 C +ATOM 4968 O SER A 331 21.711 -5.247 2.801 1.00 26.08 O +ATOM 4969 CB SER A 331 24.594 -6.766 2.691 1.00 30.03 C +ATOM 4970 OG SER A 331 25.566 -7.557 2.044 1.00 34.99 O +ATOM 4971 H SER A 331 23.211 -5.249 0.838 1.00 29.22 H +ATOM 4972 HA SER A 331 23.008 -8.013 1.876 1.00 28.06 H +ATOM 4973 HB3 SER A 331 24.578 -7.064 3.740 1.00 30.03 H +ATOM 4974 HB2 SER A 331 24.898 -5.719 2.665 1.00 30.03 H +ATOM 4975 HG SER A 331 25.398 -8.478 2.258 1.00 34.99 H +ATOM 4976 N ILE A 332 21.676 -7.210 3.940 1.00 26.63 N +ATOM 4977 CA ILE A 332 20.734 -6.799 4.982 1.00 25.76 C +ATOM 4978 C ILE A 332 21.270 -7.288 6.338 1.00 25.56 C +ATOM 4979 O ILE A 332 21.546 -8.477 6.483 1.00 25.03 O +ATOM 4980 CB ILE A 332 19.301 -7.385 4.767 1.00 25.98 C +ATOM 4981 CG1 ILE A 332 18.706 -6.971 3.397 1.00 25.58 C +ATOM 4982 CG2 ILE A 332 18.322 -7.013 5.910 1.00 24.93 C +ATOM 4983 CD1 ILE A 332 17.372 -7.647 3.060 1.00 24.29 C +ATOM 4984 H ILE A 332 22.042 -8.151 4.015 1.00 26.63 H +ATOM 4985 HA ILE A 332 20.665 -5.712 5.022 1.00 25.76 H +ATOM 4986 HB ILE A 332 19.387 -8.473 4.759 1.00 25.98 H +ATOM 4987 HG13 ILE A 332 19.402 -7.207 2.594 1.00 25.58 H +ATOM 4988 HG12 ILE A 332 18.567 -5.893 3.361 1.00 25.58 H +ATOM 4989 HG21 ILE A 332 17.328 -7.427 5.742 1.00 24.93 H +ATOM 4990 HG22 ILE A 332 18.640 -7.398 6.879 1.00 24.93 H +ATOM 4991 HG23 ILE A 332 18.217 -5.931 6.002 1.00 24.93 H +ATOM 4992 HD11 ILE A 332 17.191 -7.638 1.985 1.00 24.29 H +ATOM 4993 HD12 ILE A 332 17.363 -8.684 3.392 1.00 24.29 H +ATOM 4994 HD13 ILE A 332 16.534 -7.133 3.532 1.00 24.29 H +ATOM 4995 N ILE A 333 21.373 -6.369 7.310 1.00 23.67 N +ATOM 4996 CA ILE A 333 21.724 -6.674 8.694 1.00 22.02 C +ATOM 4997 C ILE A 333 20.440 -6.573 9.539 1.00 22.07 C +ATOM 4998 O ILE A 333 19.974 -5.473 9.831 1.00 19.54 O +ATOM 4999 CB ILE A 333 22.815 -5.724 9.275 1.00 22.12 C +ATOM 5000 CG1 ILE A 333 24.092 -5.708 8.397 1.00 19.60 C +ATOM 5001 CG2 ILE A 333 23.164 -6.116 10.732 1.00 21.06 C +ATOM 5002 CD1 ILE A 333 25.101 -4.611 8.762 1.00 20.16 C +ATOM 5003 H ILE A 333 21.156 -5.400 7.112 1.00 23.67 H +ATOM 5004 HA ILE A 333 22.112 -7.688 8.772 1.00 22.02 H +ATOM 5005 HB ILE A 333 22.423 -4.704 9.285 1.00 22.12 H +ATOM 5006 HG13 ILE A 333 23.830 -5.571 7.348 1.00 19.60 H +ATOM 5007 HG12 ILE A 333 24.590 -6.673 8.455 1.00 19.60 H +ATOM 5008 HG21 ILE A 333 24.005 -5.553 11.122 1.00 21.06 H +ATOM 5009 HG22 ILE A 333 22.333 -5.948 11.417 1.00 21.06 H +ATOM 5010 HG23 ILE A 333 23.435 -7.170 10.800 1.00 21.06 H +ATOM 5011 HD11 ILE A 333 25.798 -4.441 7.943 1.00 20.16 H +ATOM 5012 HD12 ILE A 333 24.605 -3.663 8.976 1.00 20.16 H +ATOM 5013 HD13 ILE A 333 25.694 -4.891 9.633 1.00 20.16 H +ATOM 5014 N ALA A 334 19.885 -7.739 9.893 1.00 19.22 N +ATOM 5015 CA ALA A 334 18.684 -7.884 10.708 1.00 21.48 C +ATOM 5016 C ALA A 334 19.051 -7.877 12.199 1.00 23.05 C +ATOM 5017 O ALA A 334 19.550 -8.875 12.713 1.00 22.81 O +ATOM 5018 CB ALA A 334 17.975 -9.180 10.297 1.00 20.70 C +ATOM 5019 H ALA A 334 20.340 -8.603 9.622 1.00 19.22 H +ATOM 5020 HA ALA A 334 17.999 -7.067 10.492 1.00 21.48 H +ATOM 5021 HB1 ALA A 334 17.090 -9.364 10.906 1.00 20.70 H +ATOM 5022 HB2 ALA A 334 17.653 -9.122 9.257 1.00 20.70 H +ATOM 5023 HB3 ALA A 334 18.631 -10.046 10.386 1.00 20.70 H +ATOM 5024 N THR A 335 18.818 -6.745 12.873 1.00 22.98 N +ATOM 5025 CA THR A 335 19.144 -6.551 14.283 1.00 22.61 C +ATOM 5026 C THR A 335 17.963 -6.989 15.178 1.00 23.15 C +ATOM 5027 O THR A 335 16.813 -6.705 14.845 1.00 20.17 O +ATOM 5028 CB THR A 335 19.513 -5.071 14.550 1.00 24.16 C +ATOM 5029 OG1 THR A 335 18.447 -4.191 14.261 1.00 25.56 O +ATOM 5030 CG2 THR A 335 20.736 -4.617 13.739 1.00 21.73 C +ATOM 5031 H THR A 335 18.379 -5.959 12.407 1.00 22.98 H +ATOM 5032 HA THR A 335 20.018 -7.151 14.513 1.00 22.61 H +ATOM 5033 HB THR A 335 19.746 -4.953 15.609 1.00 24.16 H +ATOM 5034 HG1 THR A 335 17.770 -4.296 14.940 1.00 25.56 H +ATOM 5035 HG21 THR A 335 21.008 -3.591 13.976 1.00 21.73 H +ATOM 5036 HG22 THR A 335 21.604 -5.240 13.954 1.00 21.73 H +ATOM 5037 HG23 THR A 335 20.550 -4.660 12.666 1.00 21.73 H +ATOM 5038 N ILE A 336 18.265 -7.699 16.280 1.00 21.79 N +ATOM 5039 CA ILE A 336 17.268 -8.275 17.194 1.00 23.08 C +ATOM 5040 C ILE A 336 17.679 -8.119 18.672 1.00 23.78 C +ATOM 5041 O ILE A 336 18.863 -7.976 18.979 1.00 23.15 O +ATOM 5042 CB ILE A 336 17.006 -9.791 16.908 1.00 23.04 C +ATOM 5043 CG1 ILE A 336 18.258 -10.693 17.057 1.00 23.18 C +ATOM 5044 CG2 ILE A 336 16.309 -9.996 15.549 1.00 22.42 C +ATOM 5045 CD1 ILE A 336 17.981 -12.195 16.922 1.00 22.53 C +ATOM 5046 H ILE A 336 19.233 -7.901 16.497 1.00 21.79 H +ATOM 5047 HA ILE A 336 16.329 -7.733 17.086 1.00 23.08 H +ATOM 5048 HB ILE A 336 16.289 -10.135 17.656 1.00 23.04 H +ATOM 5049 HG13 ILE A 336 18.712 -10.544 18.034 1.00 23.18 H +ATOM 5050 HG12 ILE A 336 19.011 -10.404 16.323 1.00 23.18 H +ATOM 5051 HG21 ILE A 336 15.961 -11.021 15.422 1.00 22.42 H +ATOM 5052 HG22 ILE A 336 15.432 -9.356 15.458 1.00 22.42 H +ATOM 5053 HG23 ILE A 336 16.976 -9.770 14.716 1.00 22.42 H +ATOM 5054 HD11 ILE A 336 18.867 -12.770 17.186 1.00 22.53 H +ATOM 5055 HD12 ILE A 336 17.172 -12.513 17.580 1.00 22.53 H +ATOM 5056 HD13 ILE A 336 17.714 -12.465 15.900 1.00 22.53 H +ATOM 5057 N SER A 337 16.668 -8.167 19.555 1.00 25.88 N +ATOM 5058 CA SER A 337 16.814 -8.197 21.010 1.00 27.99 C +ATOM 5059 C SER A 337 16.876 -9.661 21.508 1.00 28.21 C +ATOM 5060 O SER A 337 16.176 -10.506 20.948 1.00 24.65 O +ATOM 5061 CB SER A 337 15.593 -7.484 21.625 1.00 29.04 C +ATOM 5062 OG SER A 337 15.634 -7.507 23.039 1.00 32.61 O +ATOM 5063 H SER A 337 15.721 -8.266 19.211 1.00 25.88 H +ATOM 5064 HA SER A 337 17.712 -7.637 21.272 1.00 27.99 H +ATOM 5065 HB3 SER A 337 14.664 -7.951 21.296 1.00 29.04 H +ATOM 5066 HB2 SER A 337 15.554 -6.443 21.309 1.00 29.04 H +ATOM 5067 HG SER A 337 14.790 -7.178 23.372 1.00 32.61 H +ATOM 5068 N PRO A 338 17.658 -9.931 22.578 1.00 30.07 N +ATOM 5069 CA PRO A 338 17.649 -11.235 23.264 1.00 31.62 C +ATOM 5070 C PRO A 338 16.479 -11.459 24.246 1.00 32.46 C +ATOM 5071 O PRO A 338 16.252 -12.608 24.622 1.00 33.11 O +ATOM 5072 CB PRO A 338 18.993 -11.243 24.008 1.00 30.65 C +ATOM 5073 CG PRO A 338 19.242 -9.783 24.348 1.00 32.34 C +ATOM 5074 CD PRO A 338 18.653 -9.031 23.162 1.00 30.98 C +ATOM 5075 HA PRO A 338 17.639 -12.047 22.539 1.00 31.62 H +ATOM 5076 HB3 PRO A 338 19.779 -11.612 23.350 1.00 30.65 H +ATOM 5077 HB2 PRO A 338 19.001 -11.869 24.901 1.00 30.65 H +ATOM 5078 HG3 PRO A 338 20.290 -9.549 24.539 1.00 32.34 H +ATOM 5079 HG2 PRO A 338 18.678 -9.521 25.242 1.00 32.34 H +ATOM 5080 HD2 PRO A 338 18.230 -8.078 23.479 1.00 30.98 H +ATOM 5081 HD3 PRO A 338 19.414 -8.834 22.409 1.00 30.98 H +ATOM 5082 N ALA A 339 15.796 -10.384 24.679 1.00 30.89 N +ATOM 5083 CA ALA A 339 14.817 -10.410 25.770 1.00 29.88 C +ATOM 5084 C ALA A 339 13.478 -11.059 25.385 1.00 31.52 C +ATOM 5085 O ALA A 339 12.995 -10.862 24.270 1.00 27.09 O +ATOM 5086 CB ALA A 339 14.592 -8.976 26.268 1.00 31.10 C +ATOM 5087 H ALA A 339 16.020 -9.470 24.309 1.00 30.89 H +ATOM 5088 HA ALA A 339 15.253 -10.985 26.590 1.00 29.88 H +ATOM 5089 HB1 ALA A 339 13.924 -8.954 27.129 1.00 31.10 H +ATOM 5090 HB2 ALA A 339 15.531 -8.512 26.572 1.00 31.10 H +ATOM 5091 HB3 ALA A 339 14.154 -8.349 25.494 1.00 31.10 H +ATOM 5092 N SER A 340 12.893 -11.791 26.348 1.00 31.98 N +ATOM 5093 CA SER A 340 11.622 -12.516 26.238 1.00 34.26 C +ATOM 5094 C SER A 340 10.394 -11.650 25.894 1.00 34.39 C +ATOM 5095 O SER A 340 9.469 -12.153 25.256 1.00 35.26 O +ATOM 5096 CB SER A 340 11.413 -13.321 27.535 1.00 34.41 C +ATOM 5097 OG SER A 340 11.082 -12.502 28.641 1.00 35.04 O +ATOM 5098 H SER A 340 13.360 -11.883 27.239 1.00 31.98 H +ATOM 5099 HA SER A 340 11.743 -13.233 25.427 1.00 34.26 H +ATOM 5100 HB3 SER A 340 12.316 -13.879 27.777 1.00 34.41 H +ATOM 5101 HB2 SER A 340 10.617 -14.054 27.398 1.00 34.41 H +ATOM 5102 HG SER A 340 10.189 -12.168 28.521 1.00 35.04 H +ATOM 5103 N LEU A 341 10.421 -10.371 26.305 1.00 35.73 N +ATOM 5104 CA LEU A 341 9.390 -9.361 26.045 1.00 37.29 C +ATOM 5105 C LEU A 341 9.254 -8.984 24.558 1.00 36.72 C +ATOM 5106 O LEU A 341 8.204 -8.476 24.163 1.00 36.23 O +ATOM 5107 CB LEU A 341 9.729 -8.094 26.862 1.00 41.08 C +ATOM 5108 CG LEU A 341 9.662 -8.271 28.396 1.00 46.36 C +ATOM 5109 CD1 LEU A 341 10.236 -7.035 29.119 1.00 46.09 C +ATOM 5110 CD2 LEU A 341 8.241 -8.625 28.883 1.00 46.76 C +ATOM 5111 H LEU A 341 11.225 -10.048 26.824 1.00 35.73 H +ATOM 5112 HA LEU A 341 8.429 -9.764 26.365 1.00 37.29 H +ATOM 5113 HB3 LEU A 341 9.056 -7.281 26.583 1.00 41.08 H +ATOM 5114 HB2 LEU A 341 10.728 -7.758 26.579 1.00 41.08 H +ATOM 5115 HG LEU A 341 10.314 -9.105 28.661 1.00 46.36 H +ATOM 5116 HD11 LEU A 341 10.936 -7.335 29.901 1.00 46.09 H +ATOM 5117 HD12 LEU A 341 10.780 -6.377 28.440 1.00 46.09 H +ATOM 5118 HD13 LEU A 341 9.462 -6.429 29.590 1.00 46.09 H +ATOM 5119 HD21 LEU A 341 7.937 -8.041 29.752 1.00 46.76 H +ATOM 5120 HD22 LEU A 341 7.490 -8.459 28.110 1.00 46.76 H +ATOM 5121 HD23 LEU A 341 8.185 -9.675 29.171 1.00 46.76 H +ATOM 5122 N ASN A 342 10.316 -9.227 23.776 1.00 33.70 N +ATOM 5123 CA ASN A 342 10.427 -8.851 22.369 1.00 33.45 C +ATOM 5124 C ASN A 342 10.262 -10.054 21.427 1.00 33.28 C +ATOM 5125 O ASN A 342 10.554 -9.897 20.245 1.00 31.23 O +ATOM 5126 CB ASN A 342 11.779 -8.136 22.130 1.00 34.11 C +ATOM 5127 CG ASN A 342 12.017 -6.929 23.046 1.00 35.86 C +ATOM 5128 OD1 ASN A 342 12.997 -6.893 23.782 1.00 37.36 O +ATOM 5129 ND2 ASN A 342 11.125 -5.939 23.021 1.00 39.01 N +ATOM 5130 H ASN A 342 11.134 -9.666 24.178 1.00 33.70 H +ATOM 5131 HA ASN A 342 9.627 -8.170 22.080 1.00 33.45 H +ATOM 5132 HB3 ASN A 342 11.852 -7.793 21.099 1.00 34.11 H +ATOM 5133 HB2 ASN A 342 12.598 -8.843 22.271 1.00 34.11 H +ATOM 5134 HD22 ASN A 342 11.256 -5.129 23.609 1.00 39.01 H +ATOM 5135 HD21 ASN A 342 10.298 -6.000 22.443 1.00 39.01 H +ATOM 5136 N LEU A 343 9.791 -11.209 21.939 1.00 32.73 N +ATOM 5137 CA LEU A 343 9.600 -12.474 21.216 1.00 31.59 C +ATOM 5138 C LEU A 343 8.869 -12.338 19.870 1.00 31.46 C +ATOM 5139 O LEU A 343 9.404 -12.795 18.863 1.00 31.83 O +ATOM 5140 CB LEU A 343 8.906 -13.497 22.150 1.00 31.98 C +ATOM 5141 CG LEU A 343 8.491 -14.860 21.533 1.00 32.11 C +ATOM 5142 CD1 LEU A 343 9.664 -15.621 20.892 1.00 31.95 C +ATOM 5143 CD2 LEU A 343 7.759 -15.739 22.565 1.00 37.07 C +ATOM 5144 H LEU A 343 9.558 -11.238 22.922 1.00 32.73 H +ATOM 5145 HA LEU A 343 10.604 -12.840 20.998 1.00 31.59 H +ATOM 5146 HB3 LEU A 343 8.012 -13.029 22.565 1.00 31.98 H +ATOM 5147 HB2 LEU A 343 9.557 -13.686 23.004 1.00 31.98 H +ATOM 5148 HG LEU A 343 7.767 -14.660 20.743 1.00 32.11 H +ATOM 5149 HD11 LEU A 343 9.305 -16.462 20.300 1.00 31.95 H +ATOM 5150 HD12 LEU A 343 10.257 -14.991 20.231 1.00 31.95 H +ATOM 5151 HD13 LEU A 343 10.335 -16.021 21.647 1.00 31.95 H +ATOM 5152 HD21 LEU A 343 6.801 -16.084 22.174 1.00 37.07 H +ATOM 5153 HD22 LEU A 343 8.337 -16.621 22.838 1.00 37.07 H +ATOM 5154 HD23 LEU A 343 7.554 -15.199 23.490 1.00 37.07 H +ATOM 5155 N GLU A 344 7.684 -11.703 19.875 1.00 32.34 N +ATOM 5156 CA GLU A 344 6.853 -11.503 18.686 1.00 30.85 C +ATOM 5157 C GLU A 344 7.560 -10.700 17.578 1.00 28.00 C +ATOM 5158 O GLU A 344 7.491 -11.098 16.416 1.00 28.52 O +ATOM 5159 CB GLU A 344 5.503 -10.883 19.105 1.00 33.98 C +ATOM 5160 CG GLU A 344 4.516 -10.626 17.938 1.00 42.77 C +ATOM 5161 CD GLU A 344 3.134 -10.090 18.346 1.00 47.25 C +ATOM 5162 OE1 GLU A 344 2.268 -10.053 17.443 1.00 48.91 O +ATOM 5163 OE2 GLU A 344 2.947 -9.717 19.527 1.00 49.27 O1- +ATOM 5164 H GLU A 344 7.318 -11.337 20.745 1.00 32.34 H +ATOM 5165 HA GLU A 344 6.644 -12.494 18.278 1.00 30.85 H +ATOM 5166 HB3 GLU A 344 5.691 -9.947 19.635 1.00 33.98 H +ATOM 5167 HB2 GLU A 344 5.029 -11.549 19.828 1.00 33.98 H +ATOM 5168 HG3 GLU A 344 4.377 -11.553 17.380 1.00 42.77 H +ATOM 5169 HG2 GLU A 344 4.942 -9.905 17.239 1.00 42.77 H +ATOM 5170 N GLU A 345 8.252 -9.617 17.970 1.00 25.97 N +ATOM 5171 CA GLU A 345 8.998 -8.749 17.059 1.00 27.03 C +ATOM 5172 C GLU A 345 10.326 -9.344 16.580 1.00 26.23 C +ATOM 5173 O GLU A 345 10.704 -9.108 15.435 1.00 23.96 O +ATOM 5174 CB GLU A 345 9.219 -7.366 17.704 1.00 27.74 C +ATOM 5175 CG GLU A 345 7.931 -6.605 18.094 1.00 31.24 C +ATOM 5176 CD GLU A 345 6.999 -6.187 16.946 1.00 33.29 C +ATOM 5177 OE1 GLU A 345 5.950 -5.599 17.283 1.00 35.69 O +ATOM 5178 OE2 GLU A 345 7.323 -6.421 15.760 1.00 35.01 O1- +ATOM 5179 H GLU A 345 8.278 -9.368 18.948 1.00 25.97 H +ATOM 5180 HA GLU A 345 8.395 -8.643 16.161 1.00 27.03 H +ATOM 5181 HB3 GLU A 345 9.821 -6.740 17.043 1.00 27.74 H +ATOM 5182 HB2 GLU A 345 9.818 -7.495 18.606 1.00 27.74 H +ATOM 5183 HG3 GLU A 345 8.213 -5.696 18.624 1.00 31.24 H +ATOM 5184 HG2 GLU A 345 7.357 -7.196 18.809 1.00 31.24 H +ATOM 5185 N THR A 346 10.992 -10.133 17.435 1.00 25.10 N +ATOM 5186 CA THR A 346 12.191 -10.889 17.085 1.00 25.31 C +ATOM 5187 C THR A 346 11.876 -11.987 16.053 1.00 26.27 C +ATOM 5188 O THR A 346 12.596 -12.070 15.064 1.00 25.60 O +ATOM 5189 CB THR A 346 12.841 -11.524 18.339 1.00 24.58 C +ATOM 5190 OG1 THR A 346 13.329 -10.480 19.153 1.00 20.56 O +ATOM 5191 CG2 THR A 346 14.004 -12.499 18.087 1.00 23.70 C +ATOM 5192 H THR A 346 10.649 -10.254 18.380 1.00 25.10 H +ATOM 5193 HA THR A 346 12.908 -10.197 16.635 1.00 25.31 H +ATOM 5194 HB THR A 346 12.079 -12.047 18.920 1.00 24.58 H +ATOM 5195 HG1 THR A 346 13.567 -10.859 20.008 1.00 20.56 H +ATOM 5196 HG21 THR A 346 14.502 -12.770 19.018 1.00 23.70 H +ATOM 5197 HG22 THR A 346 13.653 -13.426 17.636 1.00 23.70 H +ATOM 5198 HG23 THR A 346 14.751 -12.062 17.424 1.00 23.70 H +ATOM 5199 N LEU A 347 10.775 -12.739 16.246 1.00 25.55 N +ATOM 5200 CA LEU A 347 10.278 -13.718 15.274 1.00 27.06 C +ATOM 5201 C LEU A 347 9.847 -13.071 13.949 1.00 26.24 C +ATOM 5202 O LEU A 347 10.187 -13.618 12.903 1.00 22.77 O +ATOM 5203 CB LEU A 347 9.115 -14.548 15.862 1.00 29.01 C +ATOM 5204 CG LEU A 347 9.513 -15.536 16.978 1.00 31.73 C +ATOM 5205 CD1 LEU A 347 8.254 -16.211 17.562 1.00 34.42 C +ATOM 5206 CD2 LEU A 347 10.555 -16.569 16.505 1.00 33.31 C +ATOM 5207 H LEU A 347 10.216 -12.610 17.080 1.00 25.55 H +ATOM 5208 HA LEU A 347 11.105 -14.390 15.037 1.00 27.06 H +ATOM 5209 HB3 LEU A 347 8.641 -15.118 15.061 1.00 29.01 H +ATOM 5210 HB2 LEU A 347 8.347 -13.869 16.237 1.00 29.01 H +ATOM 5211 HG LEU A 347 9.984 -14.983 17.788 1.00 31.73 H +ATOM 5212 HD11 LEU A 347 8.416 -17.258 17.818 1.00 34.42 H +ATOM 5213 HD12 LEU A 347 7.937 -15.701 18.471 1.00 34.42 H +ATOM 5214 HD13 LEU A 347 7.414 -16.175 16.868 1.00 34.42 H +ATOM 5215 HD21 LEU A 347 10.474 -17.520 17.030 1.00 33.31 H +ATOM 5216 HD22 LEU A 347 10.464 -16.771 15.438 1.00 33.31 H +ATOM 5217 HD23 LEU A 347 11.566 -16.202 16.679 1.00 33.31 H +ATOM 5218 N SER A 348 9.157 -11.916 14.006 1.00 25.08 N +ATOM 5219 CA SER A 348 8.751 -11.138 12.831 1.00 25.81 C +ATOM 5220 C SER A 348 9.954 -10.669 11.989 1.00 25.76 C +ATOM 5221 O SER A 348 9.922 -10.822 10.769 1.00 26.65 O +ATOM 5222 CB SER A 348 7.854 -9.959 13.265 1.00 27.51 C +ATOM 5223 OG SER A 348 7.412 -9.202 12.155 1.00 31.87 O +ATOM 5224 H SER A 348 8.897 -11.532 14.906 1.00 25.08 H +ATOM 5225 HA SER A 348 8.151 -11.798 12.202 1.00 25.81 H +ATOM 5226 HB3 SER A 348 8.387 -9.297 13.946 1.00 27.51 H +ATOM 5227 HB2 SER A 348 6.977 -10.326 13.799 1.00 27.51 H +ATOM 5228 HG SER A 348 6.989 -8.396 12.475 1.00 31.87 H +ATOM 5229 N THR A 349 11.003 -10.163 12.660 1.00 24.55 N +ATOM 5230 CA THR A 349 12.247 -9.724 12.031 1.00 23.43 C +ATOM 5231 C THR A 349 13.052 -10.879 11.410 1.00 24.65 C +ATOM 5232 O THR A 349 13.573 -10.697 10.312 1.00 23.30 O +ATOM 5233 CB THR A 349 13.139 -8.939 13.030 1.00 24.23 C +ATOM 5234 OG1 THR A 349 12.512 -7.695 13.268 1.00 21.82 O +ATOM 5235 CG2 THR A 349 14.592 -8.659 12.595 1.00 22.09 C +ATOM 5236 H THR A 349 10.949 -10.059 13.665 1.00 24.55 H +ATOM 5237 HA THR A 349 11.964 -9.061 11.215 1.00 23.43 H +ATOM 5238 HB THR A 349 13.169 -9.469 13.983 1.00 24.23 H +ATOM 5239 HG1 THR A 349 11.669 -7.850 13.708 1.00 21.82 H +ATOM 5240 HG21 THR A 349 15.081 -7.968 13.280 1.00 22.09 H +ATOM 5241 HG22 THR A 349 15.195 -9.568 12.582 1.00 22.09 H +ATOM 5242 HG23 THR A 349 14.630 -8.216 11.601 1.00 22.09 H +ATOM 5243 N LEU A 350 13.109 -12.041 12.084 1.00 25.56 N +ATOM 5244 CA LEU A 350 13.788 -13.237 11.584 1.00 27.20 C +ATOM 5245 C LEU A 350 13.072 -13.869 10.381 1.00 27.84 C +ATOM 5246 O LEU A 350 13.756 -14.253 9.437 1.00 27.94 O +ATOM 5247 CB LEU A 350 13.974 -14.263 12.718 1.00 26.67 C +ATOM 5248 CG LEU A 350 14.993 -13.826 13.793 1.00 28.29 C +ATOM 5249 CD1 LEU A 350 14.977 -14.792 14.987 1.00 28.78 C +ATOM 5250 CD2 LEU A 350 16.412 -13.625 13.243 1.00 27.19 C +ATOM 5251 H LEU A 350 12.660 -12.122 12.987 1.00 25.56 H +ATOM 5252 HA LEU A 350 14.774 -12.932 11.228 1.00 27.20 H +ATOM 5253 HB3 LEU A 350 14.302 -15.218 12.304 1.00 26.67 H +ATOM 5254 HB2 LEU A 350 13.004 -14.458 13.180 1.00 26.67 H +ATOM 5255 HG LEU A 350 14.691 -12.855 14.175 1.00 28.29 H +ATOM 5256 HD11 LEU A 350 15.048 -14.239 15.922 1.00 28.78 H +ATOM 5257 HD12 LEU A 350 14.062 -15.384 15.020 1.00 28.78 H +ATOM 5258 HD13 LEU A 350 15.810 -15.494 14.961 1.00 28.78 H +ATOM 5259 HD21 LEU A 350 17.171 -13.922 13.964 1.00 27.19 H +ATOM 5260 HD22 LEU A 350 16.574 -14.193 12.328 1.00 27.19 H +ATOM 5261 HD23 LEU A 350 16.593 -12.574 13.014 1.00 27.19 H +ATOM 5262 N GLU A 351 11.729 -13.918 10.405 1.00 29.78 N +ATOM 5263 CA GLU A 351 10.897 -14.351 9.279 1.00 31.65 C +ATOM 5264 C GLU A 351 11.052 -13.447 8.047 1.00 31.57 C +ATOM 5265 O GLU A 351 11.253 -13.967 6.952 1.00 32.81 O +ATOM 5266 CB GLU A 351 9.415 -14.442 9.706 1.00 34.82 C +ATOM 5267 CG GLU A 351 9.089 -15.628 10.644 1.00 41.40 C +ATOM 5268 CD GLU A 351 9.012 -17.019 9.990 1.00 44.64 C +ATOM 5269 OE1 GLU A 351 8.808 -17.977 10.768 1.00 46.61 O +ATOM 5270 OE2 GLU A 351 9.166 -17.130 8.752 1.00 43.42 O1- +ATOM 5271 H GLU A 351 11.231 -13.603 11.229 1.00 29.78 H +ATOM 5272 HA GLU A 351 11.241 -15.345 8.987 1.00 31.65 H +ATOM 5273 HB3 GLU A 351 8.760 -14.465 8.833 1.00 34.82 H +ATOM 5274 HB2 GLU A 351 9.146 -13.523 10.228 1.00 34.82 H +ATOM 5275 HG3 GLU A 351 8.128 -15.437 11.124 1.00 41.40 H +ATOM 5276 HG2 GLU A 351 9.823 -15.674 11.447 1.00 41.40 H +ATOM 5277 N TYR A 352 11.003 -12.121 8.257 1.00 31.02 N +ATOM 5278 CA TYR A 352 11.183 -11.096 7.226 1.00 29.54 C +ATOM 5279 C TYR A 352 12.561 -11.175 6.549 1.00 30.19 C +ATOM 5280 O TYR A 352 12.638 -11.172 5.320 1.00 29.15 O +ATOM 5281 CB TYR A 352 10.941 -9.712 7.861 1.00 31.28 C +ATOM 5282 CG TYR A 352 10.909 -8.538 6.899 1.00 31.74 C +ATOM 5283 CD1 TYR A 352 12.105 -7.957 6.423 1.00 32.52 C +ATOM 5284 CD2 TYR A 352 9.666 -7.997 6.508 1.00 34.47 C +ATOM 5285 CE1 TYR A 352 12.057 -6.833 5.578 1.00 34.85 C +ATOM 5286 CE2 TYR A 352 9.619 -6.861 5.679 1.00 34.55 C +ATOM 5287 CZ TYR A 352 10.814 -6.273 5.225 1.00 34.94 C +ATOM 5288 OH TYR A 352 10.764 -5.148 4.458 1.00 38.19 O +ATOM 5289 H TYR A 352 10.828 -11.777 9.193 1.00 31.02 H +ATOM 5290 HA TYR A 352 10.422 -11.259 6.461 1.00 29.54 H +ATOM 5291 HB3 TYR A 352 11.686 -9.508 8.630 1.00 31.28 H +ATOM 5292 HB2 TYR A 352 9.983 -9.726 8.383 1.00 31.28 H +ATOM 5293 HD1 TYR A 352 13.063 -8.353 6.724 1.00 32.52 H +ATOM 5294 HD2 TYR A 352 8.745 -8.431 6.867 1.00 34.47 H +ATOM 5295 HE1 TYR A 352 12.977 -6.384 5.232 1.00 34.85 H +ATOM 5296 HE2 TYR A 352 8.666 -6.434 5.408 1.00 34.55 H +ATOM 5297 HH TYR A 352 11.632 -4.825 4.208 1.00 38.19 H +ATOM 5298 N ALA A 353 13.613 -11.259 7.380 1.00 27.84 N +ATOM 5299 CA ALA A 353 15.006 -11.392 6.971 1.00 29.40 C +ATOM 5300 C ALA A 353 15.267 -12.694 6.196 1.00 30.72 C +ATOM 5301 O ALA A 353 15.927 -12.648 5.161 1.00 30.09 O +ATOM 5302 CB ALA A 353 15.882 -11.289 8.228 1.00 27.70 C +ATOM 5303 H ALA A 353 13.452 -11.242 8.379 1.00 27.84 H +ATOM 5304 HA ALA A 353 15.244 -10.552 6.315 1.00 29.40 H +ATOM 5305 HB1 ALA A 353 16.944 -11.308 7.999 1.00 27.70 H +ATOM 5306 HB2 ALA A 353 15.690 -10.351 8.749 1.00 27.70 H +ATOM 5307 HB3 ALA A 353 15.681 -12.101 8.928 1.00 27.70 H +ATOM 5308 N HIS A 354 14.709 -13.816 6.684 1.00 33.52 N +ATOM 5309 CA HIS A 354 14.829 -15.146 6.081 1.00 36.23 C +ATOM 5310 C HIS A 354 14.273 -15.219 4.648 1.00 36.11 C +ATOM 5311 O HIS A 354 14.891 -15.860 3.800 1.00 35.43 O +ATOM 5312 CB HIS A 354 14.171 -16.190 7.008 1.00 39.61 C +ATOM 5313 CG HIS A 354 14.169 -17.595 6.464 1.00 43.40 C +ATOM 5314 ND1 HIS A 354 13.043 -18.192 5.920 1.00 45.98 N +ATOM 5315 CD2 HIS A 354 15.174 -18.530 6.362 1.00 45.87 C +ATOM 5316 CE1 HIS A 354 13.408 -19.407 5.506 1.00 46.42 C +ATOM 5317 NE2 HIS A 354 14.687 -19.680 5.739 1.00 47.89 N +ATOM 5318 H HIS A 354 14.176 -13.770 7.543 1.00 33.52 H +ATOM 5319 HA HIS A 354 15.893 -15.380 6.021 1.00 36.23 H +ATOM 5320 HB3 HIS A 354 13.144 -15.904 7.235 1.00 39.61 H +ATOM 5321 HB2 HIS A 354 14.701 -16.216 7.961 1.00 39.61 H +ATOM 5322 HD1 HIS A 354 12.122 -17.784 5.848 1.00 45.98 H +ATOM 5323 HD2 HIS A 354 16.207 -18.456 6.670 1.00 45.87 H +ATOM 5324 HE1 HIS A 354 12.730 -20.102 5.032 1.00 46.42 H +ATOM 5325 N ARG A 355 13.143 -14.537 4.402 1.00 36.76 N +ATOM 5326 CA ARG A 355 12.517 -14.414 3.086 1.00 38.68 C +ATOM 5327 C ARG A 355 13.401 -13.656 2.087 1.00 37.05 C +ATOM 5328 O ARG A 355 13.551 -14.125 0.961 1.00 37.00 O +ATOM 5329 CB ARG A 355 11.158 -13.712 3.231 1.00 42.28 C +ATOM 5330 CG ARG A 355 10.110 -14.551 3.984 1.00 47.63 C +ATOM 5331 CD ARG A 355 8.919 -13.729 4.514 1.00 52.45 C +ATOM 5332 NE ARG A 355 8.232 -12.974 3.451 1.00 57.27 N +ATOM 5333 CZ ARG A 355 7.507 -13.472 2.432 1.00 59.95 C +ATOM 5334 NH1 ARG A 355 7.277 -14.783 2.267 1.00 61.16 N +ATOM 5335 NH2 ARG A 355 6.986 -12.630 1.539 1.00 59.95 N1+ +ATOM 5336 H ARG A 355 12.695 -14.036 5.158 1.00 36.76 H +ATOM 5337 HA ARG A 355 12.352 -15.418 2.688 1.00 38.68 H +ATOM 5338 HB3 ARG A 355 10.762 -13.487 2.239 1.00 42.28 H +ATOM 5339 HB2 ARG A 355 11.291 -12.749 3.725 1.00 42.28 H +ATOM 5340 HG3 ARG A 355 10.586 -15.024 4.839 1.00 47.63 H +ATOM 5341 HG2 ARG A 355 9.776 -15.392 3.378 1.00 47.63 H +ATOM 5342 HD3 ARG A 355 9.230 -13.064 5.319 1.00 52.45 H +ATOM 5343 HD2 ARG A 355 8.187 -14.406 4.955 1.00 52.45 H +ATOM 5344 HE ARG A 355 8.369 -11.974 3.483 1.00 57.27 H +ATOM 5345 HH12 ARG A 355 6.718 -15.114 1.494 1.00 61.16 H +ATOM 5346 HH11 ARG A 355 7.646 -15.447 2.932 1.00 61.16 H +ATOM 5347 HH22 ARG A 355 6.427 -12.984 0.775 1.00 59.95 H +ATOM 5348 HH21 ARG A 355 7.088 -11.629 1.640 1.00 59.95 H +ATOM 5349 N ALA A 356 13.994 -12.531 2.528 1.00 35.18 N +ATOM 5350 CA ALA A 356 14.840 -11.652 1.719 1.00 33.47 C +ATOM 5351 C ALA A 356 16.122 -12.299 1.155 1.00 34.33 C +ATOM 5352 O ALA A 356 16.671 -11.759 0.196 1.00 32.89 O +ATOM 5353 CB ALA A 356 15.169 -10.392 2.530 1.00 31.30 C +ATOM 5354 H ALA A 356 13.837 -12.235 3.482 1.00 35.18 H +ATOM 5355 HA ALA A 356 14.239 -11.344 0.861 1.00 33.47 H +ATOM 5356 HB1 ALA A 356 15.697 -9.665 1.913 1.00 31.30 H +ATOM 5357 HB2 ALA A 356 14.260 -9.909 2.892 1.00 31.30 H +ATOM 5358 HB3 ALA A 356 15.793 -10.619 3.394 1.00 31.30 H +ATOM 5359 N LYS A 357 16.542 -13.454 1.707 1.00 34.54 N +ATOM 5360 CA LYS A 357 17.620 -14.300 1.182 1.00 38.30 C +ATOM 5361 C LYS A 357 17.369 -14.808 -0.252 1.00 40.22 C +ATOM 5362 O LYS A 357 18.329 -14.975 -1.002 1.00 40.04 O +ATOM 5363 CB LYS A 357 17.807 -15.533 2.085 1.00 38.47 C +ATOM 5364 CG LYS A 357 18.277 -15.247 3.521 1.00 39.23 C +ATOM 5365 CD LYS A 357 18.350 -16.526 4.374 1.00 41.33 C +ATOM 5366 CE LYS A 357 19.476 -17.487 3.943 1.00 42.15 C +ATOM 5367 NZ LYS A 357 19.315 -18.824 4.536 1.00 41.28 N1+ +ATOM 5368 H LYS A 357 16.036 -13.828 2.497 1.00 34.54 H +ATOM 5369 HA LYS A 357 18.540 -13.714 1.182 1.00 38.30 H +ATOM 5370 HB3 LYS A 357 18.539 -16.183 1.606 1.00 38.47 H +ATOM 5371 HB2 LYS A 357 16.878 -16.104 2.112 1.00 38.47 H +ATOM 5372 HG3 LYS A 357 17.600 -14.541 4.001 1.00 39.23 H +ATOM 5373 HG2 LYS A 357 19.256 -14.769 3.492 1.00 39.23 H +ATOM 5374 HD3 LYS A 357 17.383 -17.032 4.329 1.00 41.33 H +ATOM 5375 HD2 LYS A 357 18.487 -16.248 5.420 1.00 41.33 H +ATOM 5376 HE3 LYS A 357 20.448 -17.078 4.222 1.00 42.15 H +ATOM 5377 HE2 LYS A 357 19.495 -17.633 2.866 1.00 42.15 H +ATOM 5378 HZ1 LYS A 357 18.442 -19.226 4.225 1.00 41.28 H +ATOM 5379 HZ2 LYS A 357 20.081 -19.417 4.251 1.00 41.28 H +ATOM 5380 HZ3 LYS A 357 19.302 -18.745 5.545 1.00 41.28 H +ATOM 5381 N ASN A 358 16.092 -15.061 -0.589 1.00 41.32 N +ATOM 5382 CA ASN A 358 15.650 -15.622 -1.871 1.00 42.57 C +ATOM 5383 C ASN A 358 15.533 -14.572 -2.994 1.00 43.12 C +ATOM 5384 O ASN A 358 15.154 -14.949 -4.103 1.00 44.49 O +ATOM 5385 CB ASN A 358 14.309 -16.374 -1.669 1.00 45.39 C +ATOM 5386 CG ASN A 358 14.402 -17.633 -0.795 1.00 48.23 C +ATOM 5387 OD1 ASN A 358 15.486 -18.106 -0.459 1.00 51.21 O +ATOM 5388 ND2 ASN A 358 13.247 -18.198 -0.441 1.00 48.45 N +ATOM 5389 H ASN A 358 15.361 -14.884 0.088 1.00 41.32 H +ATOM 5390 HA ASN A 358 16.405 -16.345 -2.187 1.00 42.57 H +ATOM 5391 HB3 ASN A 358 13.921 -16.708 -2.632 1.00 45.39 H +ATOM 5392 HB2 ASN A 358 13.557 -15.703 -1.253 1.00 45.39 H +ATOM 5393 HD22 ASN A 358 13.249 -19.033 0.126 1.00 48.45 H +ATOM 5394 HD21 ASN A 358 12.367 -17.799 -0.735 1.00 48.45 H +ATOM 5395 N ILE A 359 15.870 -13.298 -2.724 1.00 41.07 N +ATOM 5396 CA ILE A 359 15.922 -12.247 -3.742 1.00 40.73 C +ATOM 5397 C ILE A 359 17.249 -12.346 -4.515 1.00 41.82 C +ATOM 5398 O ILE A 359 18.304 -12.456 -3.893 1.00 42.57 O +ATOM 5399 CB ILE A 359 15.808 -10.820 -3.132 1.00 40.12 C +ATOM 5400 CG1 ILE A 359 14.491 -10.680 -2.342 1.00 40.44 C +ATOM 5401 CG2 ILE A 359 15.912 -9.700 -4.197 1.00 39.64 C +ATOM 5402 CD1 ILE A 359 14.395 -9.422 -1.478 1.00 41.20 C +ATOM 5403 H ILE A 359 16.188 -13.046 -1.799 1.00 41.07 H +ATOM 5404 HA ILE A 359 15.089 -12.384 -4.434 1.00 40.73 H +ATOM 5405 HB ILE A 359 16.629 -10.691 -2.426 1.00 40.12 H +ATOM 5406 HG13 ILE A 359 14.369 -11.526 -1.668 1.00 40.44 H +ATOM 5407 HG12 ILE A 359 13.644 -10.718 -3.026 1.00 40.44 H +ATOM 5408 HG21 ILE A 359 15.784 -8.708 -3.769 1.00 39.64 H +ATOM 5409 HG22 ILE A 359 16.881 -9.688 -4.691 1.00 39.64 H +ATOM 5410 HG23 ILE A 359 15.152 -9.819 -4.970 1.00 39.64 H +ATOM 5411 HD11 ILE A 359 13.471 -9.461 -0.913 1.00 41.20 H +ATOM 5412 HD12 ILE A 359 15.216 -9.362 -0.764 1.00 41.20 H +ATOM 5413 HD13 ILE A 359 14.376 -8.506 -2.067 1.00 41.20 H +ATOM 5414 N LEU A 360 17.148 -12.289 -5.851 1.00 42.09 N +ATOM 5415 CA LEU A 360 18.259 -12.379 -6.793 1.00 44.36 C +ATOM 5416 C LEU A 360 18.584 -10.983 -7.347 1.00 43.24 C +ATOM 5417 O LEU A 360 17.731 -10.392 -8.009 1.00 43.73 O +ATOM 5418 CB LEU A 360 17.838 -13.359 -7.916 1.00 47.52 C +ATOM 5419 CG LEU A 360 18.827 -13.511 -9.095 1.00 50.60 C +ATOM 5420 CD1 LEU A 360 20.160 -14.139 -8.649 1.00 52.74 C +ATOM 5421 CD2 LEU A 360 18.178 -14.305 -10.241 1.00 52.55 C +ATOM 5422 H LEU A 360 16.232 -12.178 -6.268 1.00 42.09 H +ATOM 5423 HA LEU A 360 19.144 -12.779 -6.296 1.00 44.36 H +ATOM 5424 HB3 LEU A 360 16.879 -13.029 -8.320 1.00 47.52 H +ATOM 5425 HB2 LEU A 360 17.647 -14.341 -7.479 1.00 47.52 H +ATOM 5426 HG LEU A 360 19.053 -12.529 -9.510 1.00 50.60 H +ATOM 5427 HD11 LEU A 360 20.456 -14.983 -9.272 1.00 52.74 H +ATOM 5428 HD12 LEU A 360 20.959 -13.402 -8.693 1.00 52.74 H +ATOM 5429 HD13 LEU A 360 20.120 -14.502 -7.622 1.00 52.74 H +ATOM 5430 HD21 LEU A 360 18.918 -14.645 -10.967 1.00 52.55 H +ATOM 5431 HD22 LEU A 360 17.650 -15.184 -9.870 1.00 52.55 H +ATOM 5432 HD23 LEU A 360 17.458 -13.689 -10.780 1.00 52.55 H +ATOM 5433 N ASN A 361 19.826 -10.525 -7.120 1.00 42.13 N +ATOM 5434 CA ASN A 361 20.409 -9.317 -7.721 1.00 44.33 C +ATOM 5435 C ASN A 361 21.481 -9.727 -8.753 1.00 45.70 C +ATOM 5436 O ASN A 361 21.829 -10.904 -8.863 1.00 46.71 O +ATOM 5437 CB ASN A 361 21.000 -8.406 -6.611 1.00 42.58 C +ATOM 5438 CG ASN A 361 19.954 -7.713 -5.722 1.00 42.14 C +ATOM 5439 OD1 ASN A 361 18.849 -8.206 -5.519 1.00 39.55 O +ATOM 5440 ND2 ASN A 361 20.302 -6.554 -5.167 1.00 40.89 N +ATOM 5441 H ASN A 361 20.470 -11.086 -6.578 1.00 42.13 H +ATOM 5442 HA ASN A 361 19.623 -8.764 -8.240 1.00 44.33 H +ATOM 5443 HB3 ASN A 361 21.589 -7.613 -7.074 1.00 42.58 H +ATOM 5444 HB2 ASN A 361 21.690 -8.964 -5.978 1.00 42.58 H +ATOM 5445 HD22 ASN A 361 19.656 -6.060 -4.566 1.00 40.89 H +ATOM 5446 HD21 ASN A 361 21.210 -6.144 -5.357 1.00 40.89 H +ATOM 5447 N LYS A 362 21.952 -8.738 -9.527 1.00 46.44 N +ATOM 5448 CA LYS A 362 22.835 -8.915 -10.684 1.00 48.00 C +ATOM 5449 C LYS A 362 24.015 -7.925 -10.624 1.00 47.90 C +ATOM 5450 O LYS A 362 24.285 -7.235 -11.609 1.00 48.26 O +ATOM 5451 CB LYS A 362 21.999 -8.754 -11.976 1.00 48.16 C +ATOM 5452 CG LYS A 362 20.896 -9.814 -12.162 1.00 50.94 C +ATOM 5453 CD LYS A 362 20.050 -9.600 -13.427 1.00 53.33 C +ATOM 5454 CE LYS A 362 19.194 -8.321 -13.372 1.00 55.16 C +ATOM 5455 NZ LYS A 362 18.323 -8.195 -14.553 1.00 55.37 N1+ +ATOM 5456 H LYS A 362 21.599 -7.799 -9.388 1.00 46.44 H +ATOM 5457 HA LYS A 362 23.276 -9.914 -10.680 1.00 48.00 H +ATOM 5458 HB3 LYS A 362 22.656 -8.802 -12.846 1.00 48.16 H +ATOM 5459 HB2 LYS A 362 21.562 -7.756 -11.977 1.00 48.16 H +ATOM 5460 HG3 LYS A 362 20.227 -9.826 -11.302 1.00 50.94 H +ATOM 5461 HG2 LYS A 362 21.355 -10.803 -12.199 1.00 50.94 H +ATOM 5462 HD3 LYS A 362 19.409 -10.471 -13.565 1.00 53.33 H +ATOM 5463 HD2 LYS A 362 20.709 -9.569 -14.297 1.00 53.33 H +ATOM 5464 HE3 LYS A 362 19.817 -7.429 -13.320 1.00 55.16 H +ATOM 5465 HE2 LYS A 362 18.567 -8.327 -12.480 1.00 55.16 H +ATOM 5466 HZ1 LYS A 362 17.768 -7.355 -14.460 1.00 55.37 H +ATOM 5467 HZ2 LYS A 362 18.883 -8.146 -15.391 1.00 55.37 H +ATOM 5468 HZ3 LYS A 362 17.708 -8.995 -14.604 1.00 55.37 H +HETATM 5469 N NME A 363 24.687 -7.866 -9.462 1.00 0.00 N +HETATM 5470 C NME A 363 25.822 -6.985 -9.210 1.00 0.00 C +HETATM 5471 H NME A 363 24.395 -8.463 -8.702 1.00 0.00 H +HETATM 5472 H1 NME A 363 26.066 -6.336 -10.052 1.00 0.00 H +HETATM 5473 H2 NME A 363 25.607 -6.348 -8.351 1.00 0.00 H +HETATM 5474 H3 NME A 363 26.705 -7.577 -8.974 1.00 0.00 H +TER 5475 NME A 363 +HETATM 5476 O HOH A 372 14.127 2.495 15.237 1.00 20.25 O +HETATM 5477 H1 HOH A 372 13.297 2.286 15.760 1.00 20.25 H +HETATM 5478 H2 HOH A 372 14.921 2.463 15.861 1.00 20.25 H +HETATM 5479 O HOH A 377 22.168 -5.652 17.068 1.00 24.29 O +HETATM 5480 H1 HOH A 377 21.799 -6.550 16.818 1.00 24.29 H +HETATM 5481 H2 HOH A 377 21.449 -5.112 17.515 1.00 24.29 H +HETATM 5482 O HOH A 395 14.808 3.792 12.670 1.00 27.35 O +HETATM 5483 H1 HOH A 395 15.161 3.112 12.024 1.00 27.35 H +HETATM 5484 H2 HOH A 395 14.745 3.389 13.587 1.00 27.35 H +HETATM 5485 O HOH A 419 26.199 -7.665 18.971 1.00 30.83 O +HETATM 5486 H1 HOH A 419 25.560 -8.426 19.111 1.00 30.83 H +HETATM 5487 H2 HOH A 419 26.576 -7.383 19.855 1.00 30.83 H +HETATM 5488 O HOH A 468 30.820 15.098 19.149 1.00 67.44 O +HETATM 5489 H1 HOH A 468 29.991 15.360 19.644 1.00 67.44 H +HETATM 5490 H2 HOH A 468 31.104 15.865 18.563 1.00 67.44 H +HETATM 5491 O HOH A 484 27.842 -6.299 21.160 1.00 38.37 O +HETATM 5492 H1 HOH A 484 28.606 -6.492 20.537 1.00 38.37 H +HETATM 5493 H2 HOH A 484 27.781 -7.031 21.842 1.00 38.37 H +HETATM 5494 O HOH A 499 22.332 5.193 9.602 1.00 41.21 O +HETATM 5495 H1 HOH A 499 22.732 5.985 10.074 1.00 41.21 H +HETATM 5496 H2 HOH A 499 21.557 4.857 10.143 1.00 41.21 H +CONECT 5476 5477 5478 +CONECT 5477 5476 +CONECT 5478 5476 +CONECT 5479 5480 5481 +CONECT 5480 5479 +CONECT 5481 5479 +CONECT 5482 5483 5484 +CONECT 5483 5482 +CONECT 5484 5482 +CONECT 5485 5486 5487 +CONECT 5486 5485 +CONECT 5487 5485 +CONECT 5488 5489 5490 +CONECT 5489 5488 +CONECT 5490 5488 +CONECT 5491 5492 5493 +CONECT 5492 5491 +CONECT 5493 5491 +CONECT 5494 5495 5496 +CONECT 5495 5494 +CONECT 5496 5494 +END diff --git a/cofactors/eg5_python_tutorial.ipynb b/cofactors/eg5_python_tutorial.ipynb new file mode 100644 index 0000000..f16811c --- /dev/null +++ b/cofactors/eg5_python_tutorial.ipynb @@ -0,0 +1,629 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "id": "35354229", + "metadata": {}, + "source": [ + "# Setting up a relative binding free energy network\n", + "\n", + "This tutorial gives a step-by-step process to set up a relative binding free energy (RBFE) simulation campaign using OpenFE when dealing with cofactors.\n", + "\n", + "**Note**: This notebook acts as a supplement to the original RBFE python tutorial, and should only be used as an example of how the code can be extended to deal with arbitrary spectator molecules." + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "id": "fc97de03", + "metadata": {}, + "outputs": [], + "source": [ + "%matplotlib inline\n", + "import openfe" + ] + }, + { + "cell_type": "markdown", + "id": "2fea29c3", + "metadata": {}, + "source": [ + "## Loading the ligands\n", + "\n", + "First we must load the chemical models between which we wish to calculate free energies.\n", + "In this example these are initially stored in a molfile (`.sdf`) containing multiple molecules.\n", + "This can be loaded using the `SDMolSupplier` class from rdkit and passed to openfe.\n", + "\n", + "#### About the data\n", + "\n", + "Here we are loading the positive ligands from the protein-ligand benchmark set's EG5 system. As charge corrections have yet to be fully implemented in OpenFE, we will stick to doing transformations without net charges for now." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "id": "41cf8be7", + "metadata": {}, + "outputs": [], + "source": [ + "from rdkit import Chem\n", + "supp = Chem.SDMolSupplier(\"eg5_ligands_positive.sdf\", removeHs=False)\n", + "ligands = [openfe.SmallMoleculeComponent.from_rdkit(mol) for mol in supp]" + ] + }, + { + "cell_type": "markdown", + "id": "6963be83", + "metadata": {}, + "source": [ + "## Creating the `LigandNetwork`\n", + "\n", + "The first step is to create a `LigandNetwork`, which is a network with small molecules as nodes, and atom mappings, the description of how to alchemically mutate between the molecules, as its edges.\n", + "\n", + "The pipeline for creating a `LigandNetwork` can involve three components:\n", + "\n", + "* **Atom Mapper**: Proposes potential atom mappings (descriptions of the alchemical change) for pairs of ligands. We will use the `LomapAtomMapper`.\n", + "* **Scorer**: Given an atom mapping, provides an estimate of the quality of that mapping (lower scores are better). We will use `default_lomap_scorer`.\n", + "* **Network Planner**: Creates the actual `LigandNetwork`; different network planners provide different strategies. We will create a minimal spanning network with the `generate_minimal_spanning_network` method.\n", + "\n", + "Each of these components could be replaced by other options." + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "5a3cf244", + "metadata": {}, + "outputs": [], + "source": [ + "mapper = openfe.LomapAtomMapper(max3d=1.0, element_change=False, threed=True)\n", + "scorer = openfe.lomap_scorers.default_lomap_score\n", + "network_planner = openfe.ligand_network_planning.generate_minimal_spanning_network" + ] + }, + { + "cell_type": "markdown", + "id": "acc13581", + "metadata": {}, + "source": [ + "The exact call signature depends on the network planner: a minimal spanning network requires a score, whereas that is optional for a radial network (but a radial network needs the central ligand to be provided)." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "id": "f6e7bce5", + "metadata": {}, + "outputs": [ + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "914f18f109784f7d90dda0f260826a06", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 1%|1 | 2/171 [00:02<03:34, 1.27s/it]" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "ligand_network = network_planner(\n", + " ligands=ligands,\n", + " mappers=[mapper],\n", + " scorer=scorer\n", + ")" + ] + }, + { + "cell_type": "markdown", + "id": "b7492637", + "metadata": {}, + "source": [ + "Now we can look at the overall structure of the `LigandNetwork`:" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "e6ca6131", + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": 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+/LpWvditgC9ecGucRteufHv+nLtaVSqevBG3ESt/fr65ufFs4S++4HidnflxTUtf7PMAupbAWbN40sqoUXy/fHk+3xdf8Azo2D+v9+954sq0aZ9+HdJKTEwMHvzX3y0JoBAiM5EWQJHq3Ny4C/b5c91jZ88a//z27bl7cc4cw8cNLftian36cPdwYq1/hlhaAtHRnLSZQuXK3P3s66t7TDOzNnYCqJEvH3dJb9nCCainZ8J1a1r3IiL4a82awLFj+rEfOsStqa6ufP/9e/2xhoCulTHucjF//MF1d++e5MtMN4KCghAVFQVra2sUTGjqtxBCZEDSAihSnacnULw40KsXJ3FhYbpJIMa0DBYqxF2VmnXqevbkBOTxYx5X6OCQsqVgwsLit3DZ2/NYuLi8vHjZkqQmnLx+zXVGR/MaegsXAvXr69f54UP8FkQHB245fPOGk+UnT/jxW7f4q6alzsmJu6RHjOAWu5w5gZEjgXLleOkXjV9/1Y1H9PXlFrrZs3Xx79/PCXnVqlzm+nWeZFO7ti6569qVl7Lp3ZvHEAYGAjNncnev5ufWsiVfmyVLeILI06e8TE21avG73Veu5MlAGWkzDU33b5EiRWAZt/9cCCEyMlNPKxbmy5hlYGxsiNzciPbu5WVJNEuXGMPXl6hJE6IcOYhsbbmekSOJnjzh48ldBobbqPRvAwbw8YSWYdHQLKsSdxkYzc3SkpdC8fIievFC97zJkw2ft25dPr56teHjkyfr6vjwgWjIEKKcOYns7IhatCB6+FA/vh49+LiNDVH58kQ+PvrHDx8mqlmTl3mxteWlbsaMiX/tLl8m+uILXr4nf36iKVN0S8Bo/PILUZkyHIuzM1G3bkSPH+uXuXWLX8ehQ4avZ3q1atUqAkCenp5KhyKEEElKTr6mIorbURNfaGgonJycEBISgmyGmkeESKYTJ3g28J073DooRHo0adIk/PDDDxgwYAB+//13pcMRQohEJSdfky5gkSZ27uSuxpIlOekbPpy7GyX5E+mZ7AIihMisZBKISBNhYcCgQTwhpHdvHnu2ezcfmzkz/np8mlvTpoqGLcycrAEohMispAtYKO7NG74ZYmeX8L67QqQ2Z2dnPHv2DOfOnUPlypWVDkcIIRIlXcAiQ8mZk29CpCfv37/Hs/+miUsLoBAis5EuYCGEMECzALSTkxNyxN17TwghMjhJAIUQwoDYE0BUn7KVjRBCpEOSAAohhAEyAUQIkZlJAiiEEAZodgGRJWCEEJmRJIAiU3n//j1q164NDw8PXLt2TelwRAYmLYBCiMxMEkCRqdjb26NIkSIICAjAsmXLlA5HZGDSAiiEyMwkARSZTvfu3QEAmzZtQlRUlMLRiIyIiGQXECFEpiYJoMh0PD09kSdPHrx8+RJ+fn5KhyMyoFevXuHdu3dQqVQoUqSI0uEIIYTJSQIoMh1ra2t07twZALB+/XqFoxEZkab1r2DBgsiSJYvC0QghhOlJAigyJU038M6dOxEWFqZwNCKjkQkgQojMThJAkSlVrVoVJUuWxIcPH7Br1y6lwxEZjEwAEUJkdpIAikxJpVJpWwGlG1gkl0wAEUJkdpIAikyrW7duAAA/Pz88e/ZM4WhERqJpAZQuYCFEZiUJoMi0ihcvjpo1a0KtVmPz5s1KhyMyEGkBFEJkdpIAikxN0woo3cDCWFFRUXj48CEAaQEUQmRekgCKTK1jx46wsrLC+fPncePGDaXDERnAo0ePoFarYWtri/z58ysdjhBCpApJAEWmlidPHnz55ZcAgA0bNigcjcgIYi8BY2Ehb5FCiMxJ3t1EpqeZDbxhwwao1WqFoxHpnUwAEUKYA0kARabXsmVLODo64sGDBzh58qTS4Yh0TiaACCHMgSSAItOzt7dHu3btAMhkEJE02QVECGEOJAEUZkHTDfzHH38gMjJS4WhEeia7gAghzIEkgMIs1KtXDwUKFEBwcDAOHDigdDgiHZMuYCGEOZAEUJgFS0tLdO3aFYB0A4uEhYaG4vXr1wCkC1gIkblJAijMhmZR6L179+Lt27fKBiPSJU33b+7cueHo6KhwNEIIkXokARRmo0KFCvjss88QERGB7du3Kx2OSIdkAogQwlxIAijMhkql0k4GkW5gYYhMABFCmAtJAIVZ0YwD9Pf31+73KoSGTAARQpgLSQCFWSlcuDDq1q0LANi0aZPC0Yj0RnYBEUKYC0kAhdnRdAOvW7cORKRwNCI9kRZAIYS5kARQmJ327dvDxsYG165dw+XLl5UOR6QTarUaDx48ACAtgEKIzE8SQGF2smfPjpYtWwIANmzYoHA0Ir149uwZPn78CEtLSxQqVEjpcIQQIlVJAijMkqYbeOPGjYiJiVE4GpEeaLp/CxcuDGtra4WjEUKI1CUJoDBLTZs2Rfbs2REUFISjR48qHY5IB2QCiBDCnEgCKMxSlixZ0LFjRwCyJqBgMgFECGFOJAEUZkvTDbxt2zZ8+PBB4WiE0qQFUAhhTiQBFGardu3aKFKkCMLCwrB3716lwxEKkxZAIYQ5kQRQmC0LCwt069YNgHQDC0kAhRDmRRJAYdY0CeCBAwfw6tUrhaMRSvn48SOePHkCQLqAhRDmQRJAYdbKlCkDDw8PREdH448//lA6HKGQf//9F0QEBwcH5M6dW+lwhBAi1UkCKMyeZjKILAptvmJPAFGpVApHI4QQqU8SQGH2OnfuDAsLC5w8eVI7DkyYFxn/J4QwN5IACrPn7OyMhg0bApBWQHMlCaAQwtxIAigEdN3A69evBxEpHI1Ia7IGoBDC3EgCKASAtm3bws7ODrdv38a5c+eUDkekMWkBFEKYG0kAhQDg6OiINm3aAJA1Ac0NEWkTQGkBFEKYC0kAhfiPpht406ZNiIqKUjgakVaCg4MRGhoKAHB1dVU2GCGESCOSAArxH09PT+TJkwcvX76En5+f0uGINKJp/XN2doa9vb3C0QghRNqQBFCI/1hbW6Nz584ApBvYnMgEECGEOZIEUIhYNN3Au3btQnh4uMLRiLQgE0CEEOZIEkAhYqlatSpKliyJ9+/fY9euXUqHI9KAtAAKIcyRJIBCxKJSqdCtWzcA0g1sLqQFUAhhjiQBFCIOTQLo6+uLZ8+eKRyNSG2aFkBJAIUQ5kQSQCHiKFGiBGrUqAG1Wo3NmzcrHY5IRTExMXjw4AEA6QIWQpgXSQCFMCD21nAi83r8+DGio6NhY2ODAgUKKB2OEEKkGUkAhTCgY8eOsLKywvnz53Hjxg2lwxGpRNP9W6RIEVhaWiocjRBCpB1JAIUwIE+ePPjyyy8BABs2bFA4GpFaZAKIEMJcSQIoRAI03cAbNmwAESkcjUgNMgFECGGuJAEUIgEtW7aEo6MjHjx4gJMnTyodjkgFmhZAmQAihDA3kgAKkQB7e3u0a9cOgEwGyaykC1gIYa4kARQiEZo1Abds2YLIyEiFoxGmJruACCHMlSSAQiSifv36cHZ2RnBwMA4cOKB0OMKE3r17h+fPnwOQFkAhhPmRBFCIRFhaWqJr164ApBs4s9EsAJ09e3Zkz55d0ViEECKtSQIoRBI0s4H37t2Lt2/fKhuMMBkZ/yeEMGeSAAqRhAoVKuCzzz5DREQEtm/frnQ4wkQkARRCmDNJAIVIgkqlkq3hMiGZACKEMGeSAAphBM04QH9/fzx69EjhaIQpSAugEMKcSQIohBEKFy6MunXrAgA2bdqkcDTCFKQFUAhhziQBFMJI0g2ceRCRtAAKIcyaJIBCGKl9+/awsbHBlStXcPnyZaXDEZ/gxYsXeP/+PVQqFYoUKaJ0OEIIkeYkARTCSNmzZ0eLFi0ASCtgRqfp/nVxcYGNjY3C0QghRNqTBFCIZNB0A2/cuBExMTEKRyNSSrp/hRDmThJAIZKhWbNmyJ49O4KCgnD06FGlwxEpJBNAhBDmThJAIZIhS5Ys6NixIwDpBs7IpAVQCGHuJAEUIpk03cDbtm3Dhw8fFI5GpISmBVASQCGEuZIEUIhkql27NooUKYKwsDDs3btX6XBECmhaAKULWAhhriQBFCKZLCws0K1bNwDAhg0bFI5GJFdUVJR2NxdpARRCmCtJAIVIAU0CuH//frx69UrhaERyPHz4EGq1GnZ2dsiXL5/S4QghhCIkARQiBcqUKYNKlSohOjoaW7duVTockQyxu39VKpXC0QghhDIkARQihWRruIxJJoAIITIrCwvj0zpJAIVIoc6dO8PCwgInT57UtiqJ9E8mgAghMisHBwejy0oCKEQKFShQAA0bNgQgk0EyElkDUAghJAEU4pPE7gYmIoWjEcaQXUCEEEISQCE+Sdu2bWFnZ4fbt2/j3LlzSocjjCAtgEIIIQmgEJ/E0dERbdq0ASCTQTKCkJAQvHnzBoC0AAohzJskgEJ8Ik038ObNmxEdHa1wNCIxmu7fPHnyJGuwtBBCZDaSAArxiTw9PZEnTx68ePECfn5+SocjEiHdv0IIwSQBFOITWVtbo1OnTgCkGzi9kwkgQiSsXj3A25u/d3UFFixQLhaR+iQBFMIENN3AO3fuRHh4uMLRiIRIC6AQxjl7Fujf37R1HjkCNGsG5MoF2NsDZcoAI0YAQUF83N8fUKmAt2/jPzduQurqymXj3mbP5uMPHvB9Kytd/RpPn/LjKhWXi11ec7OxAUqUAKZPB2Iv8DBlClCxYsKvcccOoEkTIHdurufixfhlIiKAoUO5TNasQKtWwOPH+mVu3wZat+Yy2bIBtWvz9TPk9WvAxSXha5cQSQCFMIFq1aqhRIkSeP/+PXbt2qV0OCIBsguIEMbJk4eTNFNZuhRo1AjInx/Yvh24fh34/XcgJASYNy9ldU6bxslc7NvQofplChQAfHz0H1u7FihY0HCdfn5cT2AgMHUqMGMGsGqV8TG9e8fJmiYRNcTbG9i5E9i8GTh+HAgPB1q0AGJidGWaNweio4HDh4Hz5znpbNECePYsfn19+wLlyxsfo4YkgEKYgEqlkq3hMgDZBUQI48Rtcbt5E/j8c8DWllvu/Py4xcmYz7uPHwPDhvFt1SruanZ1BerUAVasACZNSlmMjo6cUMa+Zc2qX6ZXL2D1av3H1qzhxw3JlYvrKVIE6NYNqFULuHDB+Jh69ODX06iR4eMhIcDKlZz0NmoEVKoErF8PXLnC1xQAXr0C7twBvv+eE7uSJTmhfP8euHZNv74lS7jVb+RI42PUkARQCBPp1q0bAMDX1xfPDH1ME4pSq9XSAihECqjVQJs23CJ4+jSwbBkwfrzxz9+6FYiMBEaPNnw8e3ZTRGlYq1ZAcDC3tAH89c0boGXLpJ977hwnf9Wrmy6e8+eBqCigcWPdYwUKAGXLAidP8v1cuQB3d265fPeOWwKXLgXy5QMqV9Y97/p1bgX18QGSsQWwliSAQphIiRIlUKNGDajVamzevFnpcEQcT58+RWRkJCwtLeHi4qJ0OEJkGIcOAXfvcqJRoQK3BM6YYfzzAwN5HJuzs3HlXVwABwf928OH8cuNGRO/nL+/fhlra6B7d1037qpVfN/a2vC5a9XiemxsgKpVgY4dgZ49jX6pSXr2jOvOkUP/8Xz5dN27KhXg6wsEBHArp60tMH8+cPCgLlmOiAC6dAHmzgUKF05ZLFYpfhVCiHi6d++O//3vf1i/fj28NdPpRLrw/PlzVKpUCS4uLrCykrc+IYx16xZQqBB3jWpUq2b884k4qTHWP/9w4hNbvXrxy40aBfTurf+YobF9ffsCNWsCM2dya+SpU9yqZsiWLdz6FhXF3bLDhnGyltiYPlOIfY2IgEGDgLx5+VrY2XFXeYsWPDnH2RkYO5bj/G/kUYrIu6AQJtSxY0d4e3vj/PnzuHnzJtzc3JQOSfzHw8MDF5IzmEcIASD5CVxcpUrx2LenT41rBSxaNH63sKHPbLlz80zdpJQtC7i5cYuZuzvfNzQ7F+BEV1Onuztw7x4wcSLP/rW1TfpcScmfn7vDg4P1WwFfvODWR4Anfuzbx2WyZePHFi/mVsG1a3ls4OHDnKBu28bHNTOVc+c2PhbpAhbChPLkyYMvv/wSALBhwwaFoxFCiE/n5sZdsM+f6x47e9b457dvz92ec+YYPp6cpUtSqk8f7h7u0yd5z7O05NbCyEjTxFG5Mnc/+/rqHnv6FLh6VZcAvn/PX+OO67Ow4PGYAM+kvnSJE9mLF7mFEOAWQ2NJC6AQJtatWzfs27cP69evx7Rp06D6lI/OQgihME9PoHhxnjk7Zw4QFqabBGLM21uhQjyGbcgQIDSUx9S5uvLsYB8fHnOXkqVgwsLiL4tib69rNYvNywvo0CHpCSevX3Od0dHcwrZwIVC/vn6dHz7Eb0F0cOCWwzdvOFl+8oQfv3WLv2pmKTs5cZf0iBE82SNnTp7BW66cbuZwzZrcOtirF88otrMDli8H7t/n5WEA/nnE9uoVf3V3T/z1xSYtgEKYWKtWreDg4IAHDx7gpGZalxBCZFCWlrzcS3g4T4zo1w+YMIGPGdstOmgQTyYJCgLatuVWxX79OLFKyRImACdHzs76t4RmGltZcfdoUsN/GzXielxdeSHsZs14XGBst2/z8i2xb/368bE9e/i+JlHr3Jnv//677vnz5/Os6o4dec1Ae3tg716+zgDHefAgX+8GDYAqVXj28u7dPAnHVFREsde4Niw0NBROTk4ICQlBNkOptRBCT+/evbF27VoMHDgQS5YsUTocIYQwqRMneDbwnTvxW6OEslQqlVH5mrQACpEKNItCb9myBZGmGjwihBAK2bmTx609eMALFvfvz61XkvxlXJIACpEK6tevD2dnZwQHB+PAgQNKhyOEEJ8kLIy7cd3ceOmVqlW5SxLg5VXirsenuTVtqmjYIhHSBSxEKhk5ciTmzZuH9u3bY+vWrUqHk2HUq8f7Xi5YwONwvL35JoRIn9684ZshdnYJ77srUod0AQuhME038N69exESEqJwNBnT2bPc1WRKR47wwO5cuXjwdZkyPCMvKIiP+/vzzEZDS1PE3R/V1ZXLxr1pFo198IDvW1np6td4+pQfV6m4XOzympuNDc8snD5dt84XwGuSVayY8GvcsQNo0oQHk6tUhtc8i4gAhg7lMlmz8pZZjx/rl7l9G2jdmstky8ZdfkeOGD7n69e8g0Pca/fxI7cYlSvHr7dNm4TjBnhsmZVV/Ne3YwcPhs+eneOtWBFYty7xukTayJmTf08N3ST5S78kARQilVSoUAGfffYZIiIisH37dqXDyZDy5OEkzVSWLuVZfvnz8zpa16/z7LyQkJQtQwHwXpxPn+rfhg7VL1OgAC93EdvatQn/c/Tz43oCA4GpU3nbLc1WVsZ4946TtcR2L/D25nFdmzfzDMPwcN5pICZGV6Z5c14O4/Bh3sO0YkUuY2ir6759eeP6uGJiuBVo2DDdMhcJCQnhJUIaNox/LGdOXnrk1Cng8mXg66/59tdfidcphDBMEkAhUolKpdK2Aq5fv17haDKmuC1uN2/yzENbW2658/PjFqddu5Ku6/FjTkKGDeNkql49rr9OHV5EddKklMXo6Khb40tzy5pVv0yvXsDq1fqPrVnDjxuSKxfXU6QI0K0bLxCbnE1MevTg15NQwhUSAqxcyUlvo0a8TMX69bzumZ8fl3n1imd4fv89J3YlS3JC+f49cO2afn1LlnCrn6HlPLJm5eNeXvpbiRkyYADQtSuvgxZXvXq8fIi7O088GD6c4zp+PKmrIYQwRBJAIVJRly5dAAD+/v549OiRwtFkbGo1dx/a2wOnTwPLlukWozXG1q28mn9C64QltUDsp2jVird10iQrx4/zmKmWLZN+7rlznPxVr266eM6f571OGzfWPVagAG+RpVm6MlcuTrZ8fLhFMTqaW1Dz5ePdDDSuX+dWUB+f+DsXJMfq1cDdu8DkyUmXJQL+/psX2a1TJ+XnFMKcSQIoRCoqUqQI6tSpAyLCpk2blA4nQzt0iBMEHx9eDPXzz7lr1FiBgTyOzZi9SAEezxZ3RuPDh/HLjRkTv5y/v34Za2vetF3TjbtqFd+3tjZ87lq1uB4bG55t2bEjd42ayrNnXHfsvUgBTu403bsqFS/7ERDArZy2tryA7cGDumQ5IoL3V507FyhcOOXxBAZyS+OGDYkv1BsSorsuzZsDixbxLhVCiOSTreCESGXdu3fHsWPHsH79eoxOqPlJJOnWLd5SKnY3YrVqxj8/uRva//MPJz6x1asXv9yoUTzJITZDY/v69uWuzZkzuTXy1CluVTNkyxZufYuK4m7ZYcM4WUtsTJ8pxL5GRLzsR968fC3s7LirvEULnpzj7AyMHctx/jfSIUViYrjbd+pUoFSpxMs6OvKElvBwbgH87jugWDHDPxdhOkFBQVi4cCH8/hsfkDVrVvTr1w+dO3dGlixZFI5OxBYeHm50WUkAhUhl7du3x5AhQ3DlyhVcvnwZ5Q2NlBdJSm4CF1epUtyC9PSpca2ARYvG7xY21DqVOzfPdkxK2bK8hlqXLpw0lS1reHYuwImupk53d+DePWDiRJ79a+zWW4nJn5+7w4OD9VsBX7zQbUh/+DCwbx+X0awmsXgxtwquXcstdocPc4K6bRsf18xUzp2bu+enTk06lrAw7uYOCOC9YgHu7ifi633oEG+HBXAXs+a6VKwI3LgBzJolCWBqCQ0NxYwZM7BgwQJERkbCwsICXl5emDZtGvLmzat0eMIAtVptdFnpAhYileXIkQMtWrQAIJNBPoWbG3fBPn+ue+zsWeOf3749dx3OmWP4uKFlX0ytTx/uHu7TJ3nPs7Tk1kJTbSpTuTJ3P/v66h57+hS4elWXAL5/z1/jjuuzsOAEDeCZ1JcucSJ78SK3EALcYjh4sHGxZMvGSaSmjosXgYEDgdKl+fvExj4ScTe0MK3o6GgsXboUJUqUwJw5cxAZGQlPT09cvHgRv//+uyR/mYS0AAqRBrp3744dO3Zg48aNmDVrFiw1u34Lo3l68uzPXr04iQsL000CMaZlsFAhHsM2ZAgQGspj6lxdeXawjw+PLUvJUjBhYfGXRbG317WaxeblBXTokPSEk9evuc7oaE6OFi4E6tfXr/PDh/gtiA4O3EL25g0ny0+e8OO3bvFXzSxlJyfukh4xgid75MzJM3jLldPNHK5Zk1sHe/XiGcV2dsDy5cD9+7qN7uNuA/bqFX91d9d/jdevc/L65g1fL03cFStyQlm2rH49efNyS2fsx2fN4nUAixfnuvbv55+bbLVtWocOHcKIESNw9epVAEDp0qUxb948NGvWDKpPaYIX6Q8ZISQkhABQSEiIMcWFEHF8/PiRsmfPTgDo77//VjqcdK1uXaLhw/n7IkWI5s/XHbtxg6h2bSIbGyI3N6K9e4kAooMHja/f15eoSROiHDmIbG25npEjiZ484eNHjnCdwcHxnxs3niJFuGzc24ABfPz+fb4fEGA4loAAPn7/vn55zc3SksjFhcjLi+jFC93zJk82fN66dfn46tWGj0+erKvjwweiIUOIcuYksrMjatGC6OFD/fjOniVq3JjLODoS1ahBtH9/wtc2oWuX0HVKyOTJRBUq6D82fjxRiRL8M8uRg6hmTaLNmxOuQyTPjRs3qFmzZgSAAFDOnDnpl19+ocjISKVDE8mQnHxNtoITIo0MGDAAy5YtQ58+fbBy5Uqlw8kUTpzg2cB37sim9EKkxOvXrzFlyhQsWbIEMTExsLKywpAhQzBx4kTkzJlT6fBEMiUnX5MxgEKkEc2i0Nu2bcOHDx8UjiZj2rmTx609eMALFvfvzzteSPInRPJERkZi/vz5KFGiBH799VfExMSgVatWuHbtGubPny/JnxmQBFCINFK7dm0ULlwYoaGh2Ldvn9LhZEhhYbw0iZsbL71StSqwezcfmzkz/np8mlvTpoqGLUS6QUTYvXs3ypYti++++w5v375F+fLl4efnh927d6NUUmvxiExDuoCFSEPjxo3DrFmz0KpVK+zWZC7CJN684ZshdnayKb0Qly5dwnfffYfDhw8DAPLly4fp06fj66+/lolpmURy8jWZBSxEGho0aBAePHgAS0tLhIaGygcqE8qZk29CCH3Pnj3DhAkTsGrVKhARsmTJgu+++w5jx46FY9zVzoXZkBZAIYQQIhP68OED5s+fj1mzZml3iOjUqRNmz54NV1dXZYMTqUJaAIUQQggzRUQ4dOgQfvnlFzx9+hQlS5ZE2bJlMWLECFSoUEHp8EQ6IS2AQgghhBCZgCwDI4QQQgghEiQJoBBCCCGEmZEEUAghhBDCzEgCmAbq1QO8vfl7V1dgwQLlYhFCCCGEkAQwjZ09y9tXmdKRI0CzZkCuXIC9PVCmDDBiBBAUxMf9/QGVCnj7Nv5z4yakrq5cNu5t9mw+/uAB37ey0tWv8fQpP65ScbnY5TU3GxugRAlg+nTeDl5jyhSgYsWEX+OOHUCTJkDu3FzPxYvxy0REAEOHcpmsWYFWrYDHj/XLXLgAeHoC2bPz9erfH/hvdQQ9a9YA5csDtrZA/vzAkCH6x69cAerW1S0wPG2a/usBgKNHgcqVuY5ixYDff9c/vnw58MUXQI4cfGvUCDhzJuFrIIQQQpiKJIBpLE8eTtJMZelSThzy5we2bweuX+dEIyQEmDcvZXVOm8bJXOzb0KH6ZQoUAHx89B9buzbh3Rb8/LiewEBg6lRgxgxg1SrjY3r3jvd81SSihnh7816xmzcDx49zYteiBRATw8efPOFrVaIEcPo0cPAgcO0abykW288/A+PHA99/z8f//puTT43QUE4iCxTghH7RIuCnn/h5Gvfvc1L+xRdAQAAwbhwwbBj/jDT8/YEuXTiBP3UKKFwYaNw4fmKdmPSWYAshhMggyAghISEEgEJCQowpLuKoW5do+HD+vkgRovnzdcdu3CCqXZsoSxYid3ciX18igGjnzqTrffSIyMaGyNvb8PHgYP565AjXqbkfW9x44t6P6/59rmvCBKKSJfWPlS5NNHEiH79/X798QIB+2QYNiAYN0t2fPJmoQoWEzxv3/HHre/uWyNqaaPNm3WNBQUQWFkQHD/L9pUuJ8uYlionRlQkI4PoCA/n+mzdEdnZEfn4Jx7B4MZGTE9HHj7rHZs0iKlCASK3m+6NHE7m56T9vwACiGjUSrjc6msjRkWjt2oTLxKW5Hn5+RE+fEj14QLR+PZGtLdGKFbpySV1fHx+iqVOJli83fH2JiAYOJCpYkH9HL1wgql+f64yONj5eIdKTxN6bhciIkpOvSQuggtRqoE0bbhE8fRpYtoxbnoy1dSsQGQmMHm34ePbspojSsFatgOBgbmkD+OubN0DLlkk/99w57oqtXt108Zw/D0RFcQuaRoECQNmywMmTfD8iglvILGL91tvZ6eIHAF9f/rkEBQHu7oCLC9CxI/Doke45p05x92+WLLrHmjThFkZN1/epU/qxaMqcO8dxGvL+PR9LyXZmuXJxK3CRIkC3bkCtWnyNjdWjBzBpEreQGhISAqxcya3KjRoBlSoB69dzV/jp08mPV4j0RobnKNt7cPs20Lo1l8mWjXt8jhwxfM7Xr/m92dC1I+IemVKl+D26UCFg5kzd8d69DV/Hzz7Tr+ftW2DwYMDZmYfxuLsD+/cnfB0yIkkAFXToEHD3LnelVqgAfP45d40aKzCQ/1CcnY0r7+ICODjo3x4+jF9uzJj45fz99ctYWwPdu+u6cVet4vvW1obPXasW12NjA1StyklVz55Gv9QkPXvGdefIof94vnx8DAAaNODv587lxDk4mLtmAX6DBIB79zgBnDmT33y3bePE1tOTn6M5V7588c+jOZZYmeho4NUrw6/h+++5Cz2hJMxYaZ1gX75suvMIoRQZnqPc8BwAaN6c3x8PH+b3m4oVuYzmPTW2vn15jLYhw4cDK1ZwEnjzJrB3L1Ctmu74woX61+/RI/7Q3aGDrkxkJL/nP3jA/wNu3eIx2wldw4xKtoJT0K1b/Okkf37dY7F/UZNCxJ9cjPXPP0Dcfb/r1YtfbtSo+OPiDP3i9+0L1KzJydLWrdzqFR1t+NxbtvAnqKgobjUaNoyTtcTeNEwh9jX67DN+I/zuO2DsWMDSkuPIl4+/Bzj5i4oCfvlFl+xs2sQ/oyNHdGMB4153zSfm2I8bU0Zjzhw+j78/f9pMrlq1uGUzMpLj798/7RLshBJagH+/KlbkZNrVlf8RaGbEC5GexP39vHkT6NePP1AVK8bvCZ6enMi0aZN4XY8f83vLsGHA/Pn656hTx3CLnzEcHfX/XxjSqxewejW/x2msWcOP//BD/PKa3gOAexBWreIPkH37GhdTjx78VdOyGJem92DdOt2H2/Xr+X+fnx+/p756Bdy5w+fWJHazZwOLF/M47NiveckSvn6TJgEHDuif68YNPn71KlC6tOF4nJz4prFrFzcGfP217rFVq/iD/8mTukaNIkWMuBgZjLQAKii5CVxcpUrxH5em9SopRYtyE3/sm5WBjwC5c8cvp+kqja1sWcDNjScyuLvz/YQUKsT1uLtz65+3N38K/vjRuNiTkj+/rlUvthcv9FviunblZCYoiLsRpkwBXr7kawPoWlPLlNE9J08eviaa1tL8+eN/Kn3xgr9qzpVQGSsrfsON7aefOIk+dCjhT7VJ2bKFu14uXeLvd+/mFsXUlpzfYeliyxhdbEnNgNe4c4cTkrhDTZ4+5b+z0qX5Q0lCCf/27fzzypKFv+7cmfA1SGsyPMd08RgzPCdXLv7f4OPDLYrR0dyCmi8fr6Sgcf06t4L6+OgP5dHYu5eT9X37+D3d1ZWT+DdvEo5v5UpOTGMneHv2cOPG4MEcQ9my/B4du8UyM5AEUEFubpxUPH+ue+zsWeOf3749/1OZM8fw8ZR+ykyOPn34n2yfPsl7nqUl/5FrulU/VeXK/EnN11f32NOn/EmwVq345fPl4y7pLVv4H52nJz9euzZ/vXVLV/bNG/6EqnmDqFkTOHZMP/ZDh/hNzdVVVyZ2LJoyVarod5PPncufyg8e5GMppWSCHTehTYh0saX/LrakZsBrREXxB78vvoh/LCKCf9bjx/PQFkNOnQI6deLWo0uX+GvHjulnPKkMzzH6pSbJmOE5KhW/XwYE8IcKW1tuOT14UJcsR0Tw79zcubxigiH37gH//ssJuI8Pf5g5f57/Vxry9Cm3IvbrF7+ebdv472f/fmDCBH5PSc7vQEYgXcAK8vQEihfnpvk5c4CwMN2nTGNaVQoV4j+SIUN4aZKePTkBefyYf/kdHFL2jzAsLH7rlb09v6HF5eXFYyeS+kT7+jXXGR3NXcALFwL16+vX+eFD/NYNBwdObN684TfEJ0/4cU2Clj8/35ycuMtixAhOSHLmBEaOBMqV0x9T9+uvujc8X1/u7p49Wxd/qVLcSjJ8OH/qz5aNu1Lc3DhegFs3pk7lbvJx4/jNfuZM7pLQ/NwGDuRzffcdX6NTp/iT5qZNuljmzAEmTgQ2buSfm+aaa97YP0XsBDslXcpxxU6wO3bkxzQJtrGtltLFlr672IKD+R/d3r1Aw4a6+uMOjge4nJsbl9O04mi4uvLfN5BwortgAf+sNddw7FheN3PBAv2/EaXI8Jy0HZ5DBAwaBOTNy9fCzo7H8bVowY0izs78O+LuzslsQtRqThR9fPi9HOC/jcqV+Wcat1t4zRp+74/7fqNWcyzLlvF7aeXK/L9n7lx+n88spAVQQZaWPP4gPJw/efXrx2+sgPH/tAcN4k+rQUFA27b8ptyvHycuI0emLK5Jk/gPLvYtoa4MKyvuUjLUlRxbo0Zcj6srdwM2a8ZvPLHdvs2zS2PfNJ/M9uzh+82b8/3Onfl+7MWV58/nP+SOHbnFxN6e/5lpxvcBvNCypycnhsuWcSvSsGH6cfj4cBdI8+Y829famj+Jaj5BOzlxIvT4MbfaDRrEid533+nqKFqUPzn6+3NLyw8/cILTrp2uzOLFnKC1b69/rX/6KfFraYgmwX78mD/RJpZgx77ducPH3rzh+9ev8/1bt/i+JimNnWD//Td/Uu/ena9jSrqLpIvNdPGYqovNmBnwALcgbt0K/PZbymNOaJZ83GRSKTI8J22H5xw+zN22mzfze7eHB78/2tlx67qmzNatfF2srHQfUnLnBiZP5u+dnfmYJvkD+HUB8VtUifgDSo8e3EIZm7Mz1xH7f4e7O78fmqrXKj2QFsA0ELuJPu6neDc33T8SADhxgr+WKGF8/Y0aJT5ztF69+LtUJBRPQq0MGq6uCdcFcLIT+3hS5TWmTOFbQnr3jv/JNy5bW16UedGihMvE7bozJFs2/tS4cmXCZcqV427gxNStm/hSLEld6+TQ/PwtLfnNq1mz+N0VmgQ7boz+/pxgxx4E3bkzf508WfdzmT+f31w7duRksmFD/gQd+03SWJouNn9/XSvLjBm6rvikpKSLLa737+M/NmaM7kOYxr59+q0xsbvYPv/cuC42pSboxO1ia92aW5osLPh47C622DPgFy7kpH/CBP6ZXL7M53j9mv8O16833COQnJgNzZI3NONTCbGH52jiTO7wnO+/51b+2C3UGm/fpu6HFICH5QwaxJMikiMtew80w5c0f4txx/VZWPDvJMDDPD580B07e5Zf4z//cE8awMljdDS/t2geu32bv8adxHH0KH8ANtQSX7s298yo1bqYbt/m95u4yWJGJgmgwnbu5O6+kiX5l3H4cP7l0/zyCpGY9JZgG0u62NJfF5sxM+C9vHgIRJ06nx6foVnyn9LqZkoyPCdth+fUrMl/E716cQ+UnR0vu3L/vq7XJ+7/RM3qA+7uutfYqBG3Hvbpw8MJ1GqeyOHpqd8qCPAH/OrVDbeOfvMNv88NH85jgDXDfOL2FmV00gWssLAwfmN2c+N/PFWr8gxOgH/h4g741dyaNlU0bCE+iXSxpb8uNmNmwB8+zEMUNN1wffvyz8HKKnkTWxKaJR+3VVApMjxHv0xqD8/JnZtbo8PDeb3WKlW4Z2z37oQnEhliYcH15s7NH1KaN+e/u82b9cuFhHCLYkLjcAsV4p/d2bM8ZnbYME4G02JlhbQkLYAK69kz4e6ggQN1TeZxGfqnJERGIV1s6a+LLfYMeE2XedwZ8KdO6c8s3r0b+PFHHruXnEVyNbPkv/1W99ihQ4Zn7KcmGZ6TeJ1A2vUeVKkC/PVX0vFoJHTtChTQ33PdECcnw0NAYqtZE/jf/4yPJyOSBDAdy5kzZduCCZHeSRdb+utiM2YGvGZAvca5c5xExm0B1byW8HBeZ/PiRR47pWldHD6cW2h+/JHPuXs3z1iOnXApTYbniEzP1JsLCyGERt26RMOH8/dFihDNn687duMGUe3aRDY2RG5uRHv3EgFEBw8aX7+vL1GTJkQ5chDZ2nI9I0cSPXnCx48c4TqDg+M/N248RYpw2bi3AQP4+P37fD8gwHAsAQF8/P59/fKam6UlkYsLkZcX0YsXuudNnmz4vHXr8vHVqw0fnzxZV8eHD0RDhhDlzElkZ0fUogXRw4f68Z09S9S4MZdxdCSqUYNo/379MiEhRH36EGXPzuXato1fT2yrVxM5OcV/3FC8RYrol9m6lah0aSJra/65bd+e8HmUsHYtUYkSRFmyEBUsSNSrF9GrV3xsxgyirFkN3778UtGwhZlLTr6mIkq6ETg0NBROTk4ICQlBtk+Z+iWEEAk4cYJn1d65I60sIn178ybh3SXs7DLfnrEi40hOviZdwEIIRUgXm8ioZHiOyAxkFrAQQhEyA14IIZQjXcACAPD333/j+++/R0xMDFq3bo2JEyfCwtBu20KkAeliE0KI5EtOvib/4QUAoGHDhhg1ahQuXbqEKVOmYODAgVBr1ocQAHjWp2abtubNgQ0b+Hu1GvjqK27Nun2bt0nr2ZPXWjtyJOl6N2zgsi9fJl7u3DkuFxYW/1jseAzdj+vJE67r2jXe0SMggB8PCOD7167xcc3MU015zQxUgLeNq1s36R1RUiJnzvjr8WlukvwJIcSnkwRQaHXs2BHr1q2DhYUFli9fjiFDhsCIBmKzERjIy4wAnCBpErZDh3jx0UmTeCmNSpU4AQwI4AVHk3LiBG9dlCdP4uXCw7lOZ+f43aIHDugnkNeu8Tp1cctp1j2LjOS6oqJ4oVPN+lyLFvHCq1FRfFyz76WmfKVKXI+NDfDZZ9x9a4pdIYRIb+7cuYNBgwbBw8MDHh4eaNiwIbZt24bo/7Z88ff3R+3ateHh4YG2bdvi33//VThiIZJHJoEIPV27dkVMTAx69eqFJUuWwNLSEr/88gtU6WWPpnTI3Lc1++yzzLdFkjBfL168wKRJk7B8+XKo1WrY2Nhg+PDhGD9+PJycnEBE+PHHHzF27FgQERo1aoRVq1YhR9zNmIVI5yQBFPH06NEDMTEx6NOnD3799VdYWlpi/vz5kgQmwJTbmmm240pM0aLxFx9ObFuzpBja1izuosQamm3NAC577x6wfr0kgCLji4iIwMKFCzFjxgyEhoYCANq1a4c5c+agWLFi2jL9+/eHj48PAGDQoEFYsGABrK2tFYtbiJSSLmBhUO/evbFs2TIAwMKFCzFq1CjpDk5A7G3NNJK7rZmNjW7brrjevv2k8IzSpw93D/fpk7znWVryLhfyqyEyKiLCtm3b4O7ujjFjxiA0NBSVK1fG0aNHsW3bNm3y9+LFCzRs2BA+Pj6wtLTEr7/+it9++02SP5FhSQIoEtSvXz/8/t+O3vPmzdN2eQh9sbc1u3yZx/SlZFuzhQu5O/boUeDff7meAQOAH35IWVyabc1i3/5r2IjHy4vHEGo2eE+IZluzx4953OHChdwiqHmdS5fyxve3bunfHj3i4yEhfP/4cZ5UcugQ33/1SneOmTN5qZczZ4CbN3lP7M6ddXvQBgfzhvEjR/Kkm3//BRYs4G7327d19Xz3HW/VdukSrzPo7c3JdlSU4de2Zw9PaoktKIjXJpw3j7dN272bz/P337oyV64Ahw/zNblwgeNt2dLwZB2Rvpw7dw5169ZFhw4dcP/+fRQoUABr1qzBmTNnUCfW4NYrV66gWrVqOHHiBJycnHDgwAEMHjxYwciFMAFTby0iMp/ffvuNABAAGj9+PKnVaqVDUoRsa2ae25r5+xNVqsQ/W1dXoiVL4h93d+ctw3LlIurRgygoKOHzCOU9fvyYevbsqX1fs7Ozo0mTJlF4eHi8snv27CEHBwcCQCVKlKAbN24oELEQxpGt4ITJ/fLLLxg+fDgAYMqUKZg8ebLCEaVvsq2ZEOnPu3fv8NNPP2HOnDl4//49AKB79+6YNWsWXFxc9MoSEebNm4fRo0eDiNCgQQNs3boVOWULEJGOyVZwwuSGDRuGmJgYfPfdd5gyZQosLS0xYcIEpcNKN2RbMyHSL7VajfXr12PcuHEICgoCANSuXRs///wzqhmYsh8REYFvvvkGq1evBgAMGDAAixYtkvF+IlORMYDCaN9++y3m/DdTYeLEiZg9e7bCEaUfsq2ZEOnT8ePHUb16dfTq1QtBQUFwdXXFli1b8M8//xhM/l6+fAlPT0+sXr0aFhYW+OWXX7BkyRJJ/kSmI13AItlmzZqFcePGAQDmzJmDUaNGKRxR+ibbmgmR9u7fv4/Ro0dj27ZtAABHR0eMGzcO3t7esLW1Nficq1evomXLlnjw4AGyZcuGP/74A02aNEnLsIX4JNIFLFLV2LFjER0djUmTJmH06NGwsrLCt99+q3RY6VbOnHwTQqS+0NBQzJgxAwsWLEBkZCQsLCzQr18/TJs2Dfny5UvweX/++Se6dOmCsLAwFC9eHHv37oW7u3saRi5E2pIuYJEiEydO1E4E+e6777BIs5eYEEIoIDo6GkuXLkWJEiUwZ84cREZGolGjRggICMDSpUsTTP6ICD///DNatmyJsLAw1K1bF6dPn5bkT2R6kgCKFJs8eTLG/7fg3bBhw7B48WKFIxJCmCNfX19UqlQJAwcOxMuXL1GqVCns3bsXhw4dQvny5RN8XmRkJLy8vDBixAgQEby8vHDo0CHkypUrDaMXQhnSBSxSTKVS4YcffkB0dDR+/PFHDB48GFZWVujfv7/SoQkhzMDNmzcxcuRI/PnnnwCAHDlyYMqUKfjmm2+SnLTx6tUrtGvXDseOHYOFhQXmzZuH4cOHy5aXwmxIAig+iUqlwqxZsxAdHY158+ZhwIABsLS0RN++fZUOTQiRSb1+/RpTp07FkiVLEB0dDSsrKwwePBiTJk0yap2+69evo2XLlrh37x4cHR2xZcsWNJUp+cLMSBew+GQqlQpz587VLhTt5eWFNWvWKBtUJnXo0CF4eHigfv368PDwQIMGDRAme44hMjISlStXhoeHB16/fq10ODh69CgaNmwIDw8PVKtWDWvWrEGMZi87kWKRkZFYsGABSpYsiUWLFiE6OhotW7bE1atXsWDBAqOSv4MHD6JmzZq4d+8eihYtilOnTknyJ8yTqbcWEeZLrVbT4MGDCQCpVCpat26d0iFlOu/fv6ds2bIRACpUqBABoIkTJyodluJu375NAMje3j7dbFX4/Plzat26tXa7sc8//5zu3r2rdFgZklqtpt27d1PJkiW117NcuXLk6+ubrDoWLFhAFhYWBIC++OILevnyZSpGLUTaS06+Ji2AwmRUKhUWLVqEgQMHgojQq1cvbNq0SemwMhU7Ozu0b98eAFCyZEkAwM8//4znz58rGZbi7t+/DwAoWrRouhnDlTdvXuzcuROrVq2Co6Mjjh8/jgoVKmDFihWgpJdfFf+5dOkSGjVqhNatWyMwMBB58+bFsmXLEBAQgEaNGhlVR1RUFAYOHAhvb2+o1Wr06dMHfn5+yJ07dypHL0T6JQmgMCmVSoXffvsNXl5eUKvV6N69O/744w+lw8pUevToAQA4e/YsKleujHfv3mH69OkKR6Wse/fuAeAEMD1RqVT4+uuvcfnyZXzxxRcIDw+Hl5cXWrdubfZJe1KePXsGLy8vVKpUCYcPH0aWLFnw/fffIzAwEF5eXrC0tDSqntevX6Nx48ZYtmwZVCoV5s2bhxUrVsDGxiaVX4EQ6ZskgMLkLCws8Pvvv+Prr7+GWq1G165dsX37dqXDyjTq1KmDQoUKISwsDM2bNwcALF26VJsEmSNNC2CxYsUUjsQwV1dXHDlyBHPmzIGNjQ327t2LcuXKYdeuXUqHlu58/PgRs2bNQsmSJbWtpR07dsTNmzcxa9asZO1GdfPmTVSvXh3+/v5wcHDAnj178N1336WbVmIhlCQJoEgVFhYWWL58OXr27ImYmBh07twZuzWb44pPYmFhgW7dugEAAgIC4OnpiaioKO3C3OYovbYAxmZpaYlRo0bh7NmzKF++PF6+fIm2bdvi66+/RmhoqNLhKY6IsGXLFri5uWHcuHEIDw9H1apVcfz4cWzZsgWurq7Jqu/QoUOoUaMG7t69C1dXV5w6dQotWrRIneCFyIhMPahQiNiio6Opa9euBICsra1pz549SoeUKVy7do0AkJWVFfn5+Wkn3ly6dEnp0BRRuXJlAkC7du1SOhSjfPz4kcaMGUMqlYoAUJEiRcjf31/psBRz+vRpqlWrlnaCh4uLC61bt45iYmKSXZdaraZFixaRpaWldvLNixcvUiFqIdIfmQQi0g1LS0usXbsWnTp1QlRUFNq3b4/9+/crHVaGV6ZMGVSqVAnR0dG4efMmOnbsCCLCuHHjlA5NEem9CziuLFmyYPbs2Th27BiKFi2Kf//9F/Xr18eoUaPw8eNHpcNLM48ePUK3bt1QvXp1nDx5Evb29pg6dSpu3bqF7t27w8Iief+ioqKiMGjQIAwdOhQxMTHo3bs3/Pz8kCdPnlR6BUJkYKbOKIUwJCoqitq3b08AKEuWLHTw4EGlQ8rwfv75ZwJA1atXp1u3bmlbPI4dO6Z0aGnq7du32pajsLAwpcNJttDQUOrbt6/2NZQtW5YuXryodFipKiwsjCZMmEC2trba192rVy96/Phxiut8/fo1NWjQQNsaPmfOnHSzJJAQaSU5+ZokgCLNREZGUtu2bQkA2draJmsNLxHf06dPtWua3b59mwYMGEAAqFatWmb1jy8gIIAAUJ48eZQO5ZPs3r2b8ubNqx0uMWvWLIqOjlY6LJOKiYmhVatWkbOzszbx++KLL+jcuXOfVO/Nmze1awQ6ODjQ7t27TRSxEBmLdAGLdMna2hqbN29Gq1at8PHjR7Rq1QpHjhxROqwMK3/+/PD09AQArF+/HpMmTYKtrS1OnjyJffv2KRxd2skIE0CM0apVK1y9ehVt2rRBVFQUxo4di7p162aa2d1Hjx5FlSpV0KdPHzx9+hTFihXDtm3bcPToUVSuXDnF9fr5+aFGjRoIDAxE4cKFceLECbRq1cqEkQuROUkCKNKUjY0N/vjjDzRv3hwfPnxAixYtcOzYMaXDyrA0awKuX78ezs7O2u34xo0bZzZbj2W08X+JyZMnD3bs2IHVq1fD0dERJ06cQPny5bF8+fIMu3j03bt38dVXX6FevXoICAhAtmzZMGfOHFy/fh3t2rX7pCVZFi9ejC+//BJv375FrVq1cObMGZQvX96E0QuRiZm6SVEIY3z48IG+/PJLAkBZs2al48ePKx1ShhQeHk5Zs2YlAHTixAl68+YNZc+enQDQ2rVrlQ4vTQwaNIgA0NixY5UOxaTu379PderU0XaVtmjRgp49e6Z0WEYLDg6mESNGkLW1NQEgCwsLGjhwID1//vyT646KitJuOwmAevToQR8+fDBB1EJkbNIFLNI9W1tb7NixA56ennj37h2+/PJLnDp1SumwMpysWbPiq6++AgCsW7cOOXLkwPfffw8AmDRpEiIiIpQML03E3gYuM9EsHv3TTz/BxsYG+/btQ9myZbFz506lQ0tUdHQ0Fi9ejJIlS2LevHmIiopC48aNcenSJSxZsgR58+b9pPqDg4PRrFkz/Pbbb1CpVJg9ezbWrl0LW1tbE70CIcyEqTNKIZLj3bt32pl7jo6O9L///U/pkDKcQ4cOEQDKkSMHffz4kd69e0cFChQgALRw4UKlw0t1bm5uBID8/PyUDiXVXL58mSpUqKA3Y/bt27dKhxXPgQMHqEyZMto43dzc6M8//zTZpKTbt29TqVKltD0HO3fuNEm9QmQWMgtYZCjh4eFUr149AkBOTk509uxZpUPKUKKjo7WzKjX/EJcuXaqdGRsaGqpsgKkoJiaGsmTJQgDo7t27SoeTqj5+/Ejff/+9duZ34cKF6ciRI0qHRUS8MLlmSAcAypkzJy1atIgiIyNNdo6///6bcuTIQQCoUKFCFBAQYLK6hcgsJAEUGU5YWBh98cUXBICyZ89O58+fVzqkDGXEiBEEgL766isi4iV3NMtiTJkyReHoUk9QUBABIEtLS5MmG+nZ8ePHqVixYtr17r777jvFxr+9fPmSBg0apF2D0tramr799lt68+aNSc/z+++/k5WVlXbdy6dPn5q0fiEyC0kARYYUGhqq3Q4qZ86cmX4xXFO6ePEiASAbGxvtP98tW7Zo10XLrFth/fPPPwSAXF1dlQ4lTYWGhpKXl5e2xe2zzz6jCxcupNn5IyIi6KeffiInJydtDK1bt6bbt2+b9DxRUVE0bNgw7Tm6desmkz2ESIRMAhEZkqOjIw4cOIDq1avjzZs3aNiwIa5cuaJ0WBlChQoVUK5cOURGRmLr1q0AgPbt26Ny5coIDw/HjBkzFI4wdWTWCSBJcXR0xLJly7B3717ky5cP165dQ/Xq1TFr1qxUXf6HiLBz506UKVMGI0eOREhICCpUqIDDhw9j165dKFmypMnO9fbtW7Ro0QK//PILAGDGjBlYt26dTPYQwkQkARTpSrZs2fDXX3+hatWqeP36NRo2bIhr164pHVaG0L17dwA8GxgALCwsMGvWLADAkiVL8ODBA6VCSzWZaQ3AlGjRogWuXLmCtm3bIioqCuPGjUOdOnVw9+5dk58rICAADRo0wFdffYW7d+8iX758WLFiBc6fP4/69eub9Fx37txBzZo18ddff8He3h7bt2/HuHHjPmnNQCGEPkkARbrj5OSEv/76Cx4eHnj58iUaNGiAGzduKB1Wute1a1eoVCocP35cmxh5enqiYcOGiIyMxJQpU5QNMBVkll1APkWePHmwfft2rFmzBo6Ojjh58iQqVKhgssWjnz59ij59+qBy5crw9/dHlixZMG7cOAQGBqJv376wtLQ0wavQ8ff3R/Xq1XHz5k24uLjg+PHj2qWOhBCmIwmgSJdy5MgBX19fVKxYES9evECDBg1w69YtpcNK11xcXNCgQQMAwIYNG7SPa1oBfXx8cPXqVUViSy3m3gKooVKp0KtXL1y5cgX16tXDu3fv0L9/f7Rq1QrPnj1LUZ0fPnzA9OnTUbJkSaxevRpEhM6dO+PWrVuYMWMGHB0dTfwqgOXLl8PT0xNv3rxBtWrVcObMGVSqVMnk5xFCQNYBFOnby5cvqVy5cgSAChQoQIGBgUqHlK6tXr2aAFCpUqX01l5r164dAaBWrVopGJ3pubi4EAA6deqU0qGkGzExMTRv3jzt8ji5cuWi7du3G/18tVpNGzZsoEKFCmknX1SvXp1OnjyZajFHR0eTt7e39nydO3em9+/fp9r5hMisZBawyFRevHhBn332GQEgFxeXTL/e26cIDQ0lOzs7AkCnT5/WPn7z5k3tUh0nTpxQMELT+fjxI6lUKgJgku3FMpsrV65QxYoVtUlVz549k1w8+uTJk1S9enXtcwoVKkQbN2402ULOhrx9+5aaNm2qPee0adNS9XxCZGYyC1hkKnny5MHff/8Nd3d3PH78GPXr18+UExpMwdHREW3atAEArF+/Xvt46dKl8fXXXwMAvv/+e5OMDVPav//+CyKCvb098uTJo3Q46U7ZsmVx+vRpjBs3DhYWFvDx8UH58uXh7+8fr+y///6Lzp07o1atWjh9+jSyZs2K6dOn49atW+jSpUuqTb64d+8eatWqhQMHDsDOzg5bt27FxIkTZbKHEGnB1BmlEKnl6dOnVLp0ae26b//++6/SIaVLf/75p3YXkNiLIz969IhsbW0JAP35558KRmgaBw8e1K6BJxJ34sQJ7eLRALSLR4eGhtLYsWO13cUqlYr69OlDT548SfWYjh49Srly5dIO7zh37lyqn1OIzE5aAEWmlD9/fhw+fBglS5bEgwcPUL9+fTx69EjpsNKdxo0bI2/evHj58iX++usv7eMuLi4YOnQoAGDs2LFQq9VKhWgSMgHEeLVq1cKlS5fg5eUFAPj5559RvHhxFC1aFLNmzUJERATq1auH8+fPY+XKlXB2dk7VeFatWoVGjRrh9evXqFKlCs6ePYvKlSun6jmFEPokARQZSoECBXD48GEUK1YM9+7dQ4MGDRAUFKR0WOmKlZUVunTpAkC/Gxjg7l8nJydcvnwZmzZtUiI8k5ElYJLHwcEBy5Ytw/Tp02FlZYUnT57g9evXyJUrF7Zt24bDhw+n+ozbmJgYjBw5En379kVUVBQ6duyIo0ePokCBAql6XiFEfJIAigzHxcUFR44cQdGiRXHnzh00aNAAT58+VTqsdKVHjx4AgN27dyMkJET7eM6cOTF69GgAwMSJExEZGalIfKYgLYDJExgYiNatW2PChAmIjo6GtbU1AOD169eYN29eqiweHVtoaChat26NefPmAQCmTJmCzZs3w97ePlXPK4QwTBJAkSEVLlwYR44cQZEiRXD79m00aNAAz58/VzqsdMPDwwNubm74+PEjtm/frnds+PDhyJ8/P+7fv4/ly5crFOGnkxZA4wQHB+Pbb79FmTJlsGfPHlhaWmLw4MEICgrC2rVrkS1bNpw6dQoVK1bE0qVLU2WC0P3791GrVi38+eefsLW1xebNmzF58mSZ7CGEkkw9qFCItHT37l3temVlypSR5UBimTFjBgGg+vXrxzu2ePFiAkB58+alsLAwBaL7dDly5CAAdPnyZaVDSZciIyPpl19+oZw5c2onfzRt2pSuXbumV+7BgwdUr149bZlmzZqZdBLIP//8Q7lz5yYA5OzsTGfOnDFZ3UIIfbIOoDArgYGBVLBgQQJA5cqVo5cvXyodUrrw4MED7czOhw8f6h2LjIyk4sWLEwD64YcfFIow5YKDg7UJS0ZNYFOLWq2mffv2kZubm/YalSlThg4ePJjgc2JiYujnn3/WWzx627ZtnxzL6tWrydramgCQh4cHPX78+JPrFEIkTBJAYXZu3bpFzs7OBIAqVKhAr169UjqkdKFOnToEgGbNmhXv2KZNmwgAZcuWLcMlzRcuXNAudSN0rly5Qp6entrEL3fu3LR48WKKiooy6vlXr17VWzy6R48eSS4ebUh0dDSNGjVKW0/79u3p3bt3ya5HCJE8sgyMMDulSpXC4cOHkS9fPly6dAmenp4IDg5WOizFaSaDrFu3Lt7Yro4dO6JixYoIDQ3V7hecUcgEEH0vXrzAwIEDUaFCBfj6+sLa2hojR45EYGAgvvnmG1hZWRlVz2effaa3ePS6detQrlw5HD582OhYwsLC8NVXX2Hu3LkAeLLRli1bZLKHEOmNqTNKIZR07do1ypMnDwGgKlWqUHBwsNIhKSo4OFjbrXfhwoV4xw8cOEAAKEuWLBlqYe25c+dq94w1Zx8/fqQff/yRsmXLpm1t++qrr+jOnTufXPeJEye0wwQAkLe3d5L78z548EC7d3eWLFlo48aNnxyHEMJ40gIozFaZMmVw+PBh5M6dG+fOnUOTJk30lkExN9mzZ0fLli0BcCtgXE2aNEG9evUQERGBqVOnpnV4KWbuLYBEhG3btsHd3R1jxoxBaGgoPDw84O/vj+3bt6N48eKffI5atWrh4sWLGDBgAABgwYIFqFKlCgICAgyWP3nyJKpVq4YrV64gf/78OHr0qHY9SiFE+iMJoMh0ypYti7///hs5c+bEmTNn0LRpU4SFhSkdlmI03cCbNm1CdHS03jGVSqXt/l2zZg2uX7+e5vGlhDkvAXPu3DnUrVsXHTp0wP379+Hs7IzVq1fj7NmzqFu3rknP5eDggN9//x1//vkn8ufPj+vXr6NatWqYMWOG3u/SunXrUL9+fbx48QIVK1bEmTNnUL16dZPGIoQwMVM3KQqRXly4cEG7VMjnn39utrNFIyIitHuuJjQTtE2bNgSA2rZtm8bRpYxmT2g/Pz+lQ0kzjx8/pp49e2q7ZO3s7GjixIlp9nv98uVLateunfb8NWvWpFu3btH333+vfaxt27YUHh6eJvEIIeKTWcBC/OfcuXPk5OREAKhOnTpm+89p0KBBBIC6detm8Pi1a9fIwsKCAND//ve/NI4ueWJiYrTjGu/du6d0OKkuPDycpkyZQvb29tpEq1u3bvGW9kkLarWafHx8tGMOLS0ttTGNHz+eYmJi0jwmIYSOjAEU4j+VK1fGoUOHkC1bNhw7dgwtW7bE+/fvlQ4rzWm6gXfu3Inw8PB4x8uUKYNevXoB4P2CKRV2gzCVp0+fIiIiApaWlihUqJDS4aQatVqNdevWoXTp0pgyZQrev3+PWrVq4fTp01i/fr0ir12lUqFHjx44ePAgHBwcEBMTAwCoUKECBg8eDAsL+ZciREYhf60i06tWrRr++usvODo64siRI2jdujU+fPigdFhpqnr16ihRogTev3+PnTt3GiwzZcoUZMmSBf7+/jh06FAaR2g8zQSQwoULG728SUZz/PhxVK9eHT179kRQUBCKFCmCzZs34/jx46hWrZqisf3vf/9D27ZtER4eDgcHB1hbW+PSpUsoV64ctm3bpmhsQgjjSQIozEKNGjVw4MABZM2aFX5+fmjbti0+fvyodFhpRqVSoXv37gAMzwYGOKEaPHgwAGDs2LFQq9VpFl9yZOYJIPfv30fHjh3xxRdf4Ny5c3BwcMDMmTNx8+ZNdOrUSfG9czdu3Ih69erh+fPnqFChAq5du4aLFy/Cw8MDr1+/RocOHdCjRw+8fftW0TiFEEYwdZ+yEOnZ0aNHtWOpmjVrRh8/flQ6pDRz584dAkAWFhYUFBRksMzLly/J0dGRANCmTZvSOELjTJkyhQBQ3759lQ7FZEJCQmjMmDFkY2Oj3b6vX79+9PTpU6VDIyIedzlu3DjteL/WrVvrTT6JiIigCRMmaMeRFipUiP7++28FIxbCPMkYQCESUKdOHfz555+ws7PD/v370aFDB0RGRiodVpooXrw4atWqBbVajU2bNhkskzt3bowaNQoAMGHCBERFRaVliEbJTGsAxsTEYNmyZShZsiR+/PFHREZGomHDhggICMDy5cuRP39+pUPEu3fv0KFDB8ycORMAjxHdsWMHHBwctGVsbGzwww8/4Pjx4yhRogQePXqEhg0b4ttvvzW74RZCZBimziiFyAj8/PzI1taWAFCbNm0oMjJS6ZDSxOLFi7X7JSckLCyM8ubNSwBoyZIlaReckb744gsCkOF3mfD19dXumgGASpUqRXv27CG1Wq10aFoPHz6kSpUqEQCysbGhtWvXJvmc8PBwGjhwoPZ1ubu70/nz59MgWiGELAMjhBH++usv7XIi7dq1M4sk8NWrV2RtbU0A6PLlywmWW7RoEQGg/Pnzp7ulc1xcXDLEcjUJuXnzJrVo0UKbIOXIkYMWLFhAERERSoem5/Tp05Q/f34CQHny5KETJ04k6/n79+/XPt/Kyop++OEHioqKSqVohRBEkgAKYbT9+/drx1117NjRLP5BaRZ9Hj16dIJlIiIiqGjRogSAZs6cmYbRJe7jx4+kUqkIAD1//lzpcJLl9evXNGzYMLKystImRcOGDaPXr18rHVo8mzZt0raQlytXjh48eJCiel69ekUdOnTQJrs1atSg27dvmzhaIYSGJIBCJMPevXu1rWJdunSh6OhopUNKVdu2bSMAVLBgwURf6/r16wkAOTk5pZsk5datWwSAsmbNmq66ShMTGRlJCxYs0O5KA4BatGhBN2/eVDq0eGJiYmjixInaOFu2bEmhoaGfVKdarab169drF2S3t7enxYsXZ5ifnxAZiSSAQiTTrl27tC0zPXr0yNRJ4MePHyl79uwEINGZmjExMVS+fHkCQKNGjUrDCBN24MABAkBly5ZVOpQkqdVq2rNnD5UqVUqbUJUrV458fX2VDs2gd+/eUfv27bWxjho1yqR/Bw8fPqQGDRpo6//yyy8TnI0uhEgZmQUsRDK1bt0af/zxBywtLbFu3Tr069cv3a6D96myZMmCjh07Akh4TUAAsLCw0M78XLRoER4/fpwm8SVGMwM4va8BeOnSJXh6eqJVq1a4ffs28ubNi6VLlyIgIACNGjVSOrx4goKCUKdOHWzbtg3W1tZYvXo15syZA0tLS5Odo1ChQvD19cWCBQtga2uLgwcPoly5cti6davJziGEMJ4kgEL8p23btti0aRMsLS2xZs0aDBgwINMmgZpFobdt25bo1njNmjXDF198gY8fP2LatGlpFV6C0vsSMM+ePYOXlxcqVaqEv//+GzY2NhgzZgwCAwPRv39/kyZUpnLu3DlUrVoV58+fR+7cuXH48GH07t07Vc5lYWGB4cOH4/z58/Dw8MCbN2/QsWNHdO/eXRaPFiKtmbpJUYiMbtOmTdoFbQcMGJApxyrFxMSQq6urUQs+Hz9+nACQpaWl4uPW2rVrRwBowYIFisYR14cPH2jmzJnk4OCg7eLs0KED3bt3T+nQErVlyxbtZI/PPvssTeONu3i0i4sL+fn5pdn5hciMpAtYiE/QuXNn+Pj4QKVSYenSpRgyZAiISOmwTMrCwiLJreE0ateujZYtWyImJgYTJkxIi/ASlN5aAIkIW7ZsgZubG8aNG4fw8HBUqVIF//zzD/74449021VNRJg6dSo6deqEjx8/onnz5jh58mSaxqtZPDogIACtWrVCnjx5MGrUKPz0009mtU2jEIoxdUYpRGaxZs0a7ZIjw4YNy3QtgTdv3tS27D179izRsleuXNFeizNnzqRRhPFpJq9cuXJFsRg0Tp8+TbVq1dK2+BUsWJB8fHwoJiZG6dAS9f79e+rUqZM27hEjRmTqSU9CmBNpARTCBHr16oUVK1YAAH755ReMGDEiU7UEli5dGlWrVkVMTAy2bNmSaNmyZcuiR48eAICxY8emRXjxhIWFoWjRoqhUqZKiLYDPnj3DhAkTMHDgQHz48AG1atXC77//jsDAQPTo0QMWFun3bfXly5fw8vLC7du3UbVqVezcuRM//fRTuhybKIRIXSoy4j9aaGgonJycEBISgmzZsqVFXEKkG8uXL0f//v0BAKNGjcKPP/4IlUqlcFSmsWjRIgwbNgxVqlTB2bNnEy374MEDlC5dGpGRkfD19U2Xs1mFEMKcJSdfS78fVYVIJ7y8vLBkyRIAwNy5czF+/PhM0xLYqVMnWFpa4ty5c7h582aiZV1dXfHNN98AAL7//vtMcw2EEMIcSQIohBEGDhyIRYsWAQBmzZqFKVOmKBuQieTNmxdffvklAGD9+vVJlh83bhwcHBxw/vx5+Pn5pXZ4QgghUokkgEIYaciQIZg/fz4AYNq0aeliXTxT0IztW79+fZLrHubNmxcjRowAAPz222+pHpsQQojUIQmgEMng7e2Nn376CQAwefJk7U4ZGVmrVq3g6OiIf//9F8ePH0+y/IgRI5A7d248fPgwDaITQgiRGiQBFCKZRowYgdmzZwMAxo8fjx9//FHhiD6NnZ0d2rdvD8C4bmBHR0fF1wMUIq4jR4BmzYBcuQB7e6BMGWDECCAoiI/7+wMqFWBowxFXV2DBAv37KlX8239/9njwgO9bWenq13j6lB9Xqbhc7PKam40NUKIEMH06EHso7ZQpQMWKCb/GHTuAJk2A3Lm5nosX45eJiACGDuUyWbMCrVoBcXdxvH0baN2ay2TLBtSuzdfPkNevARcXw9fujz84Xnt7oEgRYO5c/ePHj3PduXIBdnaAmxvwXyeK1po1hq+1LAWZ+iQBFCIFxowZg+nTpwPgCRHz5s1TOKJPo+kG/uOPP4xahHfgwIFwdnZO7bCEMMrSpUCjRkD+/MD27cD168DvvwMhIUBK/zSnTeNkLvZt6FD9MgUKAD4++o+tXQsULGi4Tj8/ricwEJg6FZgxA1i1yviY3r3jhEqTiBri7Q3s3Als3swJWHg40KIFEBOjK9O8ORAdDRw+DJw/z0lcixbAs2fx6+vbFyhfPv7jBw4A3boBAwcCV68CixcDP/8M/PqrrkzWrMCQIcCxY8CNG8CECXxbtky/rmzZ4l9rW1vjr4tIIVMvLCiEOZk6dap2Qd30tj1ZcsTExJCLiwsBoK1btxr1nL179yZ6vG5douHD+fsiRYjmz/+UCIUw7NEjIhsbIm9vw8eDg/nrkSNEgO5+bHF/P5P6fb1/n+uaMIGoZEn9Y6VLE02cyMfv39cvHxCgX7ZBA6JBg3T3J08mqlAh4fPGPX/c+t6+JbK2Jtq8WfdYUBCRhQXRwYN8/+VLfu6xY7oyoaH8WNyd+BYv5r/jv/+Of+26dCFq316//Pz5RC4uRImtmd+2LVH37rr7q1cTOTkl8mJFsshC0EKkkUmTJmHixIkAeHxgRp0YYWFhgW7dugEwrhsYAJo2bWp0/WfPAv8tpWgy0uXH0rLLjwj46SegVCkgSxagUCEg9jDY3r0NX8fPPtOVqVfPcJnmzRO+DonZuhWIjARGjzZ8PHv2lNVrjFatgOBgbmkD+OubN0DLlkk/99w54MIFoHp108Vz/jwQFQU0bqx7rEABoGxZ4ORJvp8rF+Duzi2X795xS+DSpUC+fEDlyrrnXb/OraA+PoChtc0jIuK30tnZ8e/ev/8aji8ggOOoW1f/8fBw7kJ2ceGWyICA5L92kXySAArxiaZOnardHWPIkCH4/fffFY4oZTTdwPv378fr16+TLJ+c3SPy5OEkzVSky08nrbr8AGD4cGDFCk4Cb94E9u4FqlXTHV+4UP/6PXoE5MwJdOigK7Njh36Zq1cBS0v9MskRGMhJrbEjElxcAAcH/Zuh+UxjxsQv5++vX8baGujeXfczXbWK71tbGz53rVpcj40NULUq0LEj0LOn0S81Sc+ecd05cug/ni+f7metUgG+vpxkOTpyEjd/PnDwoC5ZjogAunThMX2FCxs+V5Mm/LP8+29AreYPGZoPVU+f6pd1ceEPDFWqAIMHA/366Y65ufE4wD17gE2bOJ7atfnnKlKZqZsUhTBHarWaRo0ape0OXrZsmdIhpUjFihUJAP3222+fXFdiXcA3bhDVrk2UJQuRuzuRry93Me3cmXS90uWnk5ZdftevE1lZEd28mXS8Gjt3EqlURA8eJFxm/nwiR0ei8HDj641t4EDjuhA1vw8XLhAFBurfChaM//swfnz8cu/f8/HYP48rV4gcHIiePuWvV67w44Z+H/bs4XquXyfasoUoXz6iMWN05/3U34cNG/hvI65GjYgGDODv1WqiVq2ImjYlOn6c6Px5om++4Wvw5AmX+fZbok6d4l+72L8PajXR6NFEtrZElpZEOXIQTZnC5U6f1j//vXtEly8TLVtGlDMn0caNCb+2mBi+BkOHJn0dRHzSBSxEGlOpVPjxxx/x7bffAgD69++PVclp6kknYq8JmFrUaqBNG24RPH2aB4SPH2/886XLTyctu/z27gWKFQP27QOKFuVu8379+PUnZOVKbqktUiTxMp07c/d1SpQqxS2/cVudElK0KHfHx75ZWcUvlzt3/HJ2dvHLlS3LrVhduvB1Lls24XMXKsT1uLtz65+3N7dYm2rGa/78/LcRHKz/+IsX/PMGuBV43z5uMa5dG/Dw4Akcdnbcmq0ps3UrXxcrK6BhQ348d25g8mT+XqUCfvyRW5z//ZdbGDWtwa6u+ucvWhQoVw7w8gK+/ZaHPiTEwoJbR6UFMPVJAiiEiahUKsybNw9D/+s37NevH3zi9hemc126dIGFhQVOnTqFO3fupMo5Dh0C7t7lRKNCBeDzz7lr1FjS5aeTll1+9+7xP/qtW/lnt2YNJ6D/rSAUz9OnPFM0dndfXGfOcBdwYmWS0r49X4M5cwwfNzQG1NT69OHflT59kvc8S0tOyCMjTRNH5cr8u+jrq3tM081eqxbff/+ev8ZN8i0s+MMZwMMqLl3iMacXL3K3PwD88w934cZ9DQUL8s9g0yagZk0gb96EYyTi37fEjl+8aPzft0g5A597hBAppVKpsHDhQsTExGDx4sXo3bs3LC0ttRMs0jtnZ2c0atQIhw4dwvr161Nly7tbt7glJH9+3WOxx5ElhYiTGmP98w8nPrHVqxe/3KhRPIkhNkNj+/r25X9yM2dyMnTqFP8TN2TLFm7tiYoCrlwBhg3jZC2xMX2mEPsaEQGDBvE/5X/+4ZaeFSt4DODZs/yPduxYjrN794TrVKv5H7ePD7e6Adx6V7ky/0xLl9Yvv2YNJ5ht2iRc58qV3GKWnJ9/XIUKcUI7ZAgQGsoJtqsrT0bw8eEEPCXjQsPC4o+RtLfnDx9xeXnxGMakWp9fv+Y6o6P592HhQqB+ff06P3yIP9nHwYFbDt+84Q8vT57w47du8df8+fnm5MS/nyNGcMtvzpzAyJHc+taoEZetWZN/B3v1AiZN4t+H5cuB+/d1E3GKF9c//6tX/NXdXfcaX70Ctm3jv6WPH4HVq/nv4ehR3fN++40/ULi58f3jx3n8aOyxtVOnAjVqACVL8s/vl1/49WfQ+XQZi6n7lIUQvKzKgAEDCABZWFjQ5tiDtNK5devWEQAqXrw4qRNbzyEJCY0BnD+fqFgx/bIhIcaPAfz5Zy6rGa+UkNQYA6gZc1WlClG9ekRVq/L9hMZ8xR2jNWsWj6P78IHvf+qYL81YvTdv9B8vX55o0iT+3s+PxwTGffsuUYLjIeIYLCx4LJelJX8P8PeaeiZN4thje/+eyx06pP+4Ws31JzROk4jo3TuibNmITLV6kq8vUZMmPBbN1pbIzY1o5Ejd70lyfx84dda/acbRJfTz0Ejo90Fzs7Tk5VK8vIhevNA9b/Jkw+etW5ePr15t+Pjkybo6PnwgGjKEx9rZ2RG1aEH08KF+fGfPEjVuzGUcHYlq1CDavz/ha2vo2r18yc/LmpXI3p6oYUOi//1P/3m//EL02Wd8PFs2okqVeJxpTIyujLc3UeHCPHYxTx6O6+TJhGMRiUtOviYJoBCpJCYmhvr27UsAyNLS0uj19ZQWHh5OWbNmJQB08hPeiRNKAA8c4ETi2TNdWT8/4xPAhw+VmwSi+Ye/eDHfX7KE7xubAM6Zw49r3kpNNQlkyxbdY0+e6E8C2bOH74eF6T+3VCmiGTP4+zt3ePKC5rZqFZ/v5Emi58+5zF9/8WN37ujquHiRH7t1S79uzbW/ciXh17R6NU8CevUq6dcvhDBOcvI16QIWIpVYWFhg2bJliImJwZo1a9ClSxdYWlqibdu2SoeWqKxZs6Jt27ZYv3491q1bh5o1a5q0fk9P7mLq1YvHbYWF6SaBGNO1K11+ynT5NWrEEwb69OHlPtRqHg/m6anrEtZYuZInuyQ2IWLlSu4ezpUr8WsohEglps4ohRD6oqOjqXv37gSArKysaPfu3UqHlKS//vqLAFDOnDkpIiIiRXUYswyMjQ131e3dyy1GmlYrY0iXH0urLj8iXmLmq694uZN8+Yh69yZ6/Vq/zNu3HEdiKyHdumW46zgptWpxl6Pm9uWXyXu+EJldcvI1FVHsdekNCw0NhZOTE0JCQpDN0MdhIUSiYmJi0KNHD2zatAnW1tbYsWMHWrRooXRYCYqJiYGLiwuePXuGXbt2oXXr1ql6vhMneDbwnTvxW6OE0Hj0SH8GqZ1dwotwC2GOkpOvyTIwQqQBS0tL+Pj4oEOHDoiKikK7du1w8OBBpcNKkKWlJbp27QoAWLduncnr37mTl6p48IB3y+jfn9ckk+RPJEazjp7mJsmfECknCaAQacTKygobNmxAu3btEBkZiTZt2sA39oJd6YxmUei9e/firYkXUwsL46VJ3Nx46ZWqVYHdu/nYzJnx1+PT3JKx/bAQQohESBewEGksKioKHTt2xK5du2Bra4s///wTDRo0UDqseIgI5cuXx9WrV7Fs2TJ4eXmlyXnfvEl4dwnp8hNCiIRJF7AQ6Zi1tTW2bNmCli1b4uPHj2jRogWOxl49NZ1QqVTo/t/KwKnRDZyQnDnjb8ElXX5CCGFakgAKoQAbGxts3boVzZo1w4cPH9C8eXP8888/SocVT7du3aBSqfDPP//gwYMHSocjhBDCRCQBFEIhWbJkwfbt29G4cWO8e/cOzZo1w4kTJ5QOS4+Liwvq168PANiwYYPC0QiRdogI+/btwxdffAEPDw988cUX2LdvH4wYNSVEhiAJoBAKsrW1xa5du9CwYUOEh4ejadOm+N///qd0WHpidwPLPz9hLlQqFVq0aAEfHx/Y29vj+PHjaNmyJTp16oQ3CQ1SFSIDkQRQCIXZ2dlhz549qF+/PsLCwtCkSROcPXtW6bC02rVrB1tbW9y6dQvnz59P9vPPnTsHDw8PVKtWDSdOnMB3330HDw8PeHh4oEaNGpg/f36Cs4xnzZoFDw8P/JbEzvDBwcHaOqOiopIdY1o5ceIE6tSpAw8PD7Rq1Qr37t1TOiSRhKJFi+Lo0aOYMWMGrKyssHXrVpQrVw5+fn5KhybEpzH1ytJCiJQJDw+nOnXqEADKnj07nTt3TumQtDp37kwAaNiwYSl6ft26dQmA9mZhYUF9+/alh3G3rIijSZMmBIBWrFiRaLkLFy4QAMqXL1+K4kttarWa5s+fTxYWFgSA6tSpQy9fvlQ6LJFMZ8+epVKlSml/j7/99lv68OGD0mEJoZWcfE1aAIVIJ7JmzYo///wTtWvXxtu3b+Hp6YmLcTeJVYimG3jTpk3JamF7+fIlvL29cfLkSe1jDRs2xNWrV7FixQoUKlQo0effv38fALfCJObx48cAeMxiehMZGYkBAwbg22+/hVqtRp8+feDr64vcuXMrHZpIpipVquDChQv45ptvAADz589H1apVcfnyZYUjEyL5JAEUIh1xcHDAgQMHULNmTQQHB6NRo0bp4p9L48aNkSdPHrx8+RKHDh1KsnxYWBimTp2KYsWKYeHChYiKikLevHkB8Axod3f3JOtQq9XamcfFihVLtGx6TQBfv36NJk2aYPny5VCpVJg3bx5WrFgBGxsbpUMTKZQ1a1YsXrwY+/btQ968eXH16lVUrVoVP//8M9RqtdLhCWE0SQCFSGccHR1x4MABVKtWDa9fv9a2mCnJ2toaXbp0AQCsX78+wXIRERFYuHAhihUrhilTpiA8PBweHh44dOgQjh8/DisrKxw4cMCodQ+fPHmCyMhIWFpaJpnYpccE8ObNm6hevTr8/f3h6OiIvXv34rvvvoNKpVI6NGECzZs3x5UrV9CyZUtERkZixIgR8PT01P4uCpHeSQIoRDrk5OSEv/76C5UrV8arV6/QoEEDXL9+XdGYNFvD7dq1C6GhoXrHYmJisHbtWpQqVQre3t549eoVSpYsiT/++ANnz56Fp6cnSpYsqd1NZOzYsUnOKNZ0/xYpUgRWVlaJlk1vCeChQ4dQo0YN3L17F66urjh58iSaN2+udFjCxPLmzYvdu3dj6dKlsLe3x+HDh1GuXDn88ccfSocmRJIkARQincqePTsOHTqESpUq4eXLl2jQoAFu3rypWDyVK1dG6dKl8fHjR2zfvh0Ar5W2Z88eVKhQAb1798bDhw9RoEABLFu2DNeuXUOHDh1gYaF7m5k4cSLs7e1x6tQp7NmzJ9HzaWbIJjX+D0g/CSARYdGiRWjatClCQkLw+eef48yZMyhbtqyicYnUo1Kp0L9/fwQEBKBq1ap4+/YtOnXqhJ49eyIkJETp8IRIkCSAQqRjOXPmhK+vLypUqIDnz5+jQYMGCAwMVCQWlUqlbQVcv349jh07htq1a6N169a4du0asmfPjh9//BGBgYHw8vKCtbV1vDqcnZ3h7e0NABg3bhxiYmISPJ+mBTCp8X9A+kgAo6KiMGjQIAwbNgxqtRq9e/eGn58f8uTJo1hMIu2UKlUKJ06cwMSJE2FhYYF169ahQoUK6XKHHyEAyDIwQmQEL1++pHLlyhEAKliwIN25c0eROO7fv6+3nAsAsrOzo7Fjx9KbN2+MqiM4OJhy5MhBAGjNmjUJluvRowcBoJkzZyZan1qtJnt7ewJAgYGByXo9pvL69Wtq0KABASCVSkVz5swhtVqtSCxCeSdOnKCiRYtqlzwaN24cRUREKB2WMAOyDIwQmUzu3Lnh5+eHMmXKICgoCPXr19e2kKWVu3fvYty4cdr7FhYW+Oabb3D37l3MnDkTOXLkMKqe7NmzY+zYsQCASZMm4ePHjwbLGbsEzNu3b/H+/XsAQMGCBY2KwZRu3bqFGjVq4PDhw3BwcMDu3bsxatQomexhxmrVqoWLFy/i66+/hlqtxsyZM1GrVi1Fh3AIEZckgEJkEHnz5sXhw4fh5uaGR48eoX79+vj3339T/bzPnj3D4MGD4ebmhk2bNmkfL1asGH777Tc4Ozsnu84hQ4agYMGCePjwIX7//XeDZYztAtZ0/+bKlQt2dnbJjuVT+Pr6okaNGggMDEThwoVx4sQJtGzZMk1jEOlTtmzZsGrVKmzduhU5c+bE+fPn4eHhgSVLlsiWiiJdkARQiAwkX758OHz4MEqVKoV///0X9evXx8OHD1PlXG/fvsX48eNRvHhxLF68GNHR0fjyyy9x9OhR2NjY4M6dO7h06VKK6razs8OUKVMAADNmzIg3q/jjx48ICgoCkH4XgV68eDGaNm2Kt2/folatWjh79izKly+fpjGI9K99+/a4fPkyPD098eHDBwwaNAgtWrTA8+fPlQ5NmDlJAIXIYJydnXH48GEUL14c9+/fR4MGDUy69tiHDx8wd+5cFCtWDDNnzsT79+9Ro0YNHDlyBAcOHECdOnW0rVzr1q1L8Xl69+6N0qVL49WrV5g3b57eMU3LpoODQ5I7ZqR1AhgdHY0hQ4Zg8ODBiImJQc+ePXH48GHtQtdCxFWwYEEcPHgQCxYsQJYsWbB//36UK1cuyZnwQqQmSQCFyIAKFiyII0eOoFixYrh79y4aNGiAJ0+efFKd0dHRWLFiBUqWLInRo0cjODgYZcqUwa5du3Dy5EnUq1dPW1YzG3jjxo2JzuRNjJWVFWbMmAEAmDdvHl68eKE9FnsJmKTG0qVlAhgcHIymTZvit99+g0qlwuzZs7FmzRpkyZIl1c8tMjYLCwsMHz4c586dQ/ny5fHy5Uu0bt0aAwYMwLt375QOT5ghSQCFyKAKFSqEI0eOwNXVFYGBgWjQoAGePXuW7HqICNu2bUPZsmXh5eWFoKAgFCpUCKtXr8bly5fRunXreElY06ZNkTNnTjx79gx///13il/DV199hSpVquDdu3faZBAwfgIIkHYJYGBgIGrUqAE/Pz9kzZoVO3bswJgxY2Syh0iWsmXL4syZMxg5ciRUKhWWLVuGSpUq4cyZM0qHJsyMJIBCZGCFCxfGkSNHULhwYdy6dQsNGjTQa0lLip+fH6pVq4YOHTrg1q1byJ07N+bPn4/bt2+jd+/esLS0NPg8GxsbdOrUCcCndQNrWtEAYMmSJdrEL72tAXj48GFUr14dt2/fRqFChXDixAm0adMm1c4nMrcsWbJg7ty58PPzg4uLCwIDA1GrVi388MMPiI6OVjo8YSYkARQig3N1dcXhw4fh4uKCGzduoGHDhnj58mWizzl37hw8PT3h6emJc+fOwcHBAZMnT8bdu3fh7e0NW1vbJM+r6QbesWMHwsPDUxx/w4YN4enpiaioKEyePBlA+toFZOnSpWjcuDGCg4NRo0YNnDlzBhUqVEiVcwnz0qBBA1y+fBmdOnVCTEwMJk2ahDp16uDu3btKhybMgakXFhRCKOP27dtUoEABAkDly5enly9fxitz8+ZNat++vXYRZ2traxo2bBg9f/482edTq9VUvHhxAkDr1q37pNjPnj2rXUT58uXLVKlSJQJAe/fuTfK52bJlIwB048aNT4ohrqioKBo6dKj2WnXr1o0+fPhg0nMIQcR/S+vXr9f+Ljs4ONCqVatkMXGRbMnJ1yQBFCITuXnzJuXPn58AUMWKFen169dERPTo0SPq168fWVpaahOtnj170v379z/pfJMnTyYA1Lhx40+OvUOHDgSAWrRoQU5OTgSArl69muhzNO9NACg0NPSTY9AIDg6mxo0ba+ueMWOG/DMWqe7BgwdUp04d7e/dV199Ra9evVI6LJGBSAIohBm7fv065c2bV9sSOHToULK1tdX+U2nVqhVduXLFJOcKDAzUbnf15MmTT6rr1q1b2gRVc3v37l2iz7l+/ToBICcnp086d2yBgYHk5uZGAMje3p62b99usrqFSEp0dDTNnj2brK2tCQA5OzvTX3/9pXRYIoOQreCEMGPu7u7Yt28f7O3tcfnyZSxatAgfP37E559/juPHj2P37t0oW7asSc5VokQJ1KxZE2q1Wm+XkJQoVaoU+vbtq72fL18+2NvbJ/ocU4//O3LkCKpXr46bN2/CxcUFx48fx1dffWWSuoUwhqWlJcaMGYP//e9/cHNzw9OnT9GkSRMMHz4cHz58UDo8kYlIAihEJhIZGYnFixejZcuW2v1xAaB06dLYt28fateubfJzdu/eHcCnzQbWmDRpEqytrQHwnsFJMWUCuHz5cjRu3Bhv3rxBtWrVcObMGVSqVOmT6xUiJTw8PHD+/HkMGTIEAPDLL7+gSpUquHjxorKBiUxDEkAhMgG1Wo2NGzfC3d0dgwcPxvPnz7U7eeTIkQO3bt1Cs2bNEBYWZvJzd+rUCdbW1rh48SKuXr36SXUVLFhQm6Q+e/YsyUWmTZEARkdH49tvv0X//v0RHR2Nzp07w9/fP0V7HAthSvb29li0aBH279+PfPny4fr166hWrRrmzp0LtVqtdHgig5MEUIgMjIhw4MABeHh4oFu3brh37x7y5cuHX3/9FTdu3MDYsWPh5+eH7Nmz4+TJk2jevLnJdx3IlSsXmjVrBgBYv379J9enWfolJCQkyW7lT00AQ0JC0KpVKyxYsAAA8MMPP2Djxo2ws7NLUX1CpIamTZviypUraN26NaKiojB69Gg0bNgQjx49Ujo0kYFJAihEBnXq1CnUq1cPzZo1w6VLl5AtWzZMnz4dd+7cweDBg2FjYwOAu5J8fX3h5OSEf/75By1atNDrHjaFIUOGoFKlSrh06dInt0zY29ujUqVKqFSpEjZv3ozIyMgEy2bJkgWVKlVK0bp8jx49Qp8+ffDs2TPUrFkTvr6+mDBhguzsIdKlPHnyYOfOnVixYgWyZs0Kf39/lCtXDps3b1Y6NJFBqYiIkioUGhoKJycnhISEIFu2bGkRlxAiAdeuXcP48eOxe/duAJwEDR06FN9//z1y5cqV4PNOnz4NT09PhIWFoUGDBti7d2+SkyyEEOnPnTt30L17d5w+fRoA0K1bN/z6669GjZsVmVty8jVpARQig/j333/Ru3dvlCtXDrt374aFhQX69u2LwMBAzJ07N9HkDwCqV6+OgwcPwsHBAYcPH0abNm3w8ePHNIpeCGEqJUqUwPHjxzF58mRYWlpiw4YNqFChAo4ePap0aCIDkQRQiHTu5cuX8Pb2RqlSpbB27VoQEdq1a4dr165hxYoVKFSokNF11apVCwcOHEDWrFnh6+uLtm3bIiIiIhWjF0KkBisrK0yZMgX//PMPihcvjocPH6J+/fr4/vvvEx02IYSGJIBCpFNhYWGYOnUqihUrhoULFyIyMhINGjTA6dOnsW3bNri5uaWo3s8//xz79++Hvb09Dh48iHbt2kkSKEQGVbNmTQQEBKBv374gIvz444+oXr06rl+/rnRoIp2TBFCIdCYiIgILFy5EsWLFMGXKFISHh6Ny5co4dOgQ/Pz8UK1atU8+R506dbBv3z7Y2dnhzz//RKdOnaTVQIgMytHREStWrMCOHTuQK1cuXLx4EZUrV8avv/4KI4b5CzMlCaAQ6URMTAzWrl2LUqVKwdvbG69evULJkiXxxx9/4MyZM/D09DTpDNX69etjz549sLW1xe7du9GlSxdERUWZrH4hRNpq27Ytrly5giZNmuDjx48YOnQomjVrhqdPnyodmkiHJAEUQmFEhN27d6NChQro3bs3Hj58iAIFCmDZsmW4du0aOnToAAuL1PlTbdSoEXbt2gUbGxvs2LED3bp1Q3R0dLLqqFcP8Pbm711dgf+W1BNCKMDZ2RkHDhzAokWLYGtri4MHD6JcuXLYuXOn0qGJdEYSQCEUdOzYMdSuXRtt2rTBtWvXkCNHDsyZMwd37tyBl5eXdlu01NSkSRPs3LkT1tbW2Lp1K3r06JHsJFDj7Fmgf3/TxnfkCNCsGZArF2BvD5QpA4wYAQQF8XF/f0ClAt6+jf/cuAmpqyuXjXubPZuPP3jA962sdPVrPH3Kj6tUXC52ec3NxgYoUQKYPh2I3fM2ZQpQsWLCr3HHDqBJEyB3bq7H0G5fERHA0KFcJmtWoFUr4L91sLVu3wZat+Yy2bIBtWvz9YvN0Ov//Xf9MkTATz8BpUoBWbIAhQoBM2fGj2f8eKBIES5TvDiwapV+mbdvgcGDAWdnwNYWcHcH9u9P+DoI01CpVBgyZAjOnz+PihUr4vXr1/jqq6/Qr18/hIeHKx2eSCckARRCARcvXkSzZs1Qt25dnDp1CnZ2dhg7dizu3buHUaNGpflOFM2aNcP27dthbW2NzZs3o3fv3kluw2ZInjycpJnK0qVAo0ZA/vzA9u3A9eucrISEAPPmpazOadM4mYt9GzpUv0yBAoCPj/5ja9cCBQsartPPj+sJDASmTgVmzIifDCXm3TtO1jSJqCHe3sDOncDmzcDx40B4ONCiBRD7x9S8ORAdDRw+DJw/z0lnixbAs2f6da1erf/6e/XSPz58OLBiBSeBN28Ce/cCcYeeduwI/P03sHIlcOsWsGkTEHteUmQk4OnJSfK2bVxm+fKEr6EwvTJlyuD06dMYM2YMVCoVVq5ciYoVK+J///uf0qGJ9ICMEBISQgAoJCTEmOJCiATcuXOHunTpQgAIAFlZWdE333xDT548UTo0IiLauXMnWVlZEQDq2bMnRUdHJ/mcunWJhg/n74sUIZo/X3fsxg2i2rWJsmQhcncn8vUlAoh27kw6lkePiGxsiLy9DR8PDuavR45wnZr7scWNJ+79uO7f57omTCAqWVL/WOnSRBMn8vH79/XLBwTol23QgGjQIN39yZOJKlRI+Lxxzx+3vrdviaytiTZv1j0WFERkYUF08CDff/mSn3vsmK5MaCg/5ueneyyp63/9OpGVFdHNmwmXOXCAyMmJ6PXrhMssWUJUrBhRZGTCZUTa8ff3p8KFCxMAsrS0pMmTJ1NUVJTSYQkTS06+Ji2AQqSBp0+fYvDgwXBzc9Pub9ulSxfcuHEDixcvhrOzs8IRsjZt2mDz5s2wtLSEj48P+vfvn+Kt3dRqoE0bbhE8fRpYtoy7DI21dSu3Io0ebfh4am560KoVEBzMLW0Af33zBmjZMunnnjsHXLgAVK9uunjOnweiooDGjXWPFSgAlC0LnDzJ93Pl4i5WHx9uUYyO5hbUfPmAypX16xsyhLuJq1blFtXYP+K9e4FixYB9+4CiRbnbvF8/fv0ae/YAVaoAc+Zwi16pUsDIkcCHD/platbkLuB8+TjWmTP1WyxF2qlbty4uXbqEbt26ISYmBlOnTsXnn3+OO3fuKB2aUIgkgEKkordv32L8+PEoUaIEFi9ejOjoaHz55Ze4cOECNm7ciBIlSigdYjzt2rXDxo0bYWFhgVWrVmFm3MFfRjp0CLh7lxOSChWAzz/nrlFjBQbyODZjc2MXF8DBQf/28GH8cmPGxC/n769fxtoa6N5d1427ahXfT2hIZq1aXI+NDSdVHTsCPXsa/VKT9OwZ150jh/7j+fLpundVKsDXFwgIABwdeczd/PnAwYP6yfIPP3By7ecHdO7M4ylj/4jv3QP+/ZfL+PgAa9ZwAtq+vX6Z48eBq1e5W3rBAu7mHTxYv8y2bZzw7d8PTJjA3fbJ+R0QppU9e3asX78eGzduhJOTE06fPo2KFStixYoVslyMGbJSOgAhMqMPHz7g119/xaxZsxAcHAwAqFGjBmbNmoV69eopG5wROnbsiOjoaPTo0QM7duzAhAkTkl3HrVs8eSB/ft1jyVnCkIiTGmP98w8nPrEZutSjRgG9e+s/ZmhcWt++3II1cyYnQ6dOcauaIVu2cOtbVBRw5QowbBgna4mN6TOF2NeICBg0CMibl6+FnR2P42vRgifnaBLp2D9KzcSUadN0j6vVPMHDx4db9gAe51e5Mv9MS5fmMioVsGED4OTEZX7+mZPE337jc6vVHMuyZYClJT//yRNg7lxg0qTUvS4icV26dEHt2rXRq1cv+Pv7w8vLC/v27cPy5cuRJ08epcMTaURaAIUwoejoaKxYsQIlS5bE6NGjERwcjDJlymDXrl04efJkhkj+NLp27Yo1a9akeO3B5CZwcZUqxZM9jF3CrGhRnoEb+2Zl4CNu7tzxyxmac1O2LE9q6NKFk7uyZRM+d6FCXI+7O7f+eXtza5eptlrOn5+7w//7LKH14gW3AgI88WPfPp4kUrs24OEBLF7Mr23t2oTrrlEDCA0Fnj/n+87OfN00yR/ArwvQtag6O3PSrEn+NGWIdDOTnZ25DktL/TLPnvFrEcoqXLgw/v77b8ydOxfW1tbYvXs3ypUrhwMHDigdmkgjkgAKYQJEhG3btuGzzz6Dl5cXgoKCULhwYaxevRqXL19G69atTbqIc1rp0aMHJk+enKLnurlxwqBJLABuiTJW+/bc7TlnjuHjhpZ9MbU+fbh7uE+f5D3P0pJbC02V6FSuzN3Pvr66x54+5S7YWrX4/vv3/DXukpEWFvpj/OIKCODuYk03ce3aHPvdu7oyt2/z1yJFdGWePOGZyLHLWFhwV7ymzJ07+ue+fZsTQxsbo162SGUWFhYYOXIkzpw5gzJlyuD58+do1qwZhgwZgveaXyiRaUkCKMQn0mzP1qFDB9y+fRu5c+fG/PnzcevWLfTu3RuWsZtAMqBWrVql6Hmenrw2XK9ewOXLwIkTukkgxuTChQrxGLaFC7k79uhRHpt24gQwYACPZUuJsDBuhYp9Cw01XNbLC3j5kidBJOb1a67n8WPgwAGOuX59HsOo8eEDr+8X+6YZf//mDd/XbN966xbf14zvc3LiazBiBC+9EhDAYxLLleNlcgDurs6Rg6/3pUucbI0aBdy/z8vDADzBY/lyThzv3uUu4vHjee3GLFm4TKNG3HrYpw+f5/x5vt6enrpWwa5dedLJ119zzMeO8bn69NG1pn7zDV+X4cM5lj//5O702OMERfpQsWJFnDt3DsOHDwcA/Pbbb6hSpQouXLigcGQiVZl6WrEQ5uLs2bPUqFEj7ZIuDg4ONHnyZLP7OzFmGRgbGyI3N6K9e3kZEs3SJcbw9SVq0oQoRw4iW1uuZ+RIIs3KOcldBoY7KvVvAwbw8YSWYdEICDC8DIzmZmlJ5OJC5OVF9OKF7nmTJxs+b926fHz1asPHJ0/W1fHhA9GQIUQ5cxLZ2RG1aEH08KF+fGfPEjVuzGUcHYlq1CDav193/MABoooViRwciOzticqWJVqwgCjuaiBBQURffcXl8uUj6t07/pIvN24QNWrEsbi4EH33HdH79/plTp4kql6dlwEqVoxoxgwiI1YWEgr666+/yNnZmQCQtbU1zZ4926jloET6kJx8TUWU9NSf0NBQODk5ISQkBNlif6QVwgzdunULEyZMwLZt2wAA1tbW+OabbzB+/HjkzZtX4ejStxMneDbwnTvcOiiESH9ev36N/v37Y8eOHQCAOnXqwMfHB0U0YwBEupWcfE26gIUw0uPHj+Hl5YXPPvsM27Ztg0qlQs+ePXH79m0sXLhQkj8Ddu7kcWsPHvCyI/3789gwSf6ESL9y5cqFbdu2YdWqVXBwcMCxY8dQvnx5bNiwQZaLyUQkARQiCW/evMHo0aNRsmRJrFixAjExMWjVqhUuX76MtWvXwtXVVekQ062wMF6axM2Nl16pWhXYvZuPzZwZfz0+za1pU0XDFsLsqVQqfP3117h48SJq1qyJ0NBQdO/eHV27dtUubSUyNukCFiIB7969w8KFCzFnzhyEhIQAAL744gvMnj0btTRTL0WKvXmjv7tEbHZ2smesEOlFdHQ0Zs2ahalTpyImJgYuLi7w8fFB/fr1lQ5NxJGcfE0SQCHiiIyMxIoVKzBt2jQ8/28Nk/Lly2PWrFlo2rRphlzORQghPtWZM2fQrVs33LlzByqVCiNGjMD06dORRTOFXChOxgAKkQJqtRobN26Eu7s7Bg8ejOfPn6NYsWLYsGEDAgIC0KxZM0n+hBBmq1q1aggICED//v1BRPjpp59QrVo1XL16VenQRApIAijMHhHhwIED8PDwQLdu3XDv3j3ky5cPv/76K27cuIGuXbvCIu7qukIIYYYcHBywdOlS7N69G7lz58bly5dRpUoVLFy4EOrEVhwX6Y78VxNmTbM9W7NmzXDp0iVky5YN06dPx507dzB48GDYyJYFQggRT6tWrXDlyhU0a9YMERER8Pb2xpdffoknT54oHZowkiSAwixdvXoVrVu3Ru3atXHs2DFkyZIFI0eOxL179zB+/Hg4ODgoHaIQQqRr+fPnx759+7B48WLY2dnB19cX5cqVw/bt25UOTRhBEkBhVv7991/07t0b5cuXx549e2BhYYG+ffsiMDAQc+fORa5cuZQOUQghMgyVSoVvvvkGFy5cgIeHB968eYP27dvj66+/RmhCeyyKdEESQGEWXrx4AW9vb5QqVQpr164FEaFdu3a4du0aVqxYgUKFCikdohBCZFhubm44deoUxo0bB5VKhTVr1qBixYo4ceKE0qGJBEgCKDK10NBQTJkyBcWLF8fChQsRGRmJBg0a4MyZM9i2bRvc3NyUDlEIITIFGxsbzJgxA0ePHkWRIkVw//591KlTBxMnTkRUVJTS4Yk4JAEUmVJERAQWLlyI4sWLY+rUqQgPD0flypXh6+uLv//+G1WrVlU6xHSnXj3A25u/d3UFFixQLhYhRMb1xRdf4NKlS+jZsyfUajWmT5+O2rVr4/bt20qHJmKRBFBkKjExMVi7di1KlSoFb29vvHr1CiVLlsQff/yBM2fOoFGjRkqHmCGcPcv79prSkSNAs2ZArlyAvT1QpgwwYgQQFMTH/f0BlQp4+zb+c+MmpK6uXDbubfZsPv7gAd+3stLVr/H0KT+uUnG52OU1NxsboEQJYPp0IPZS+VOmABUrJvwad+wAmjQBcufmei5ejF8mIgIYOpTLZM0KtGoFPH6sX+b2baB1ay6TLRvvn3zkiO74pUtAly5AoUK8a4q7O7BwoX4d/v5ch7Mzn6diRWDDhoRjP3GCr4uh17dgAVC6NJ+rUCHg22+Bjx8TrksIJycnrF27Flu2bEGOHDlw9uxZVKpUCcuWLZP9hNMJSQBFpkBE2L17NypUqIDevXvj4cOHKFCgAJYtW4Zr166hQ4cOspZfMuTJw0maqSxdCjRqBOTPD2zfDly/Dvz+OxASAsybl7I6p03jZC72behQ/TIFCgA+PvqPrV2b8DZzfn5cT2AgMHUqMGMGsGqV8TG9e8fJmiYRNcTbG9i5E9i8GTh+HAgPB1q0AGJidGWaNweio4HDh4Hz5zkpa9ECePaMj58/zz+j9euBa9eA8eOBsWOBX3/V1XHyJFC+PF/vy5eBPn2Anj2BvXvjxxQSwscaNox/bMMG4PvvgcmTgRs3gJUrgS1b+HxCJKVjx464fPkyGjZsiPfv32PAgAFo3bo1Xrx4oXRogowQEhJCACgkJMSY4kKkqaNHj1LNmjUJAAGgHDly0Jw5c+j9+/dKh5ah1K1LNHw4f1+kCNH8+bpjN24Q1a5NlCULkbs7ka8vEUC0c2fS9T56RGRjQ+Ttbfh4cDB/PXKE69Tcjy1uPHHvx3X/Ptc1YQJRyZL6x0qXJpo4kY/fv69fPiBAv2yDBkSDBunuT55MVKFCwueNe/649b19S2RtTbR5s+6xoCAiCwuigwf5/suX/Nxjx3RlQkP5MT+/hM85aBBR/fqJx9WsGdHXX8d/vFMnvlaGXt/gwXwdYvvuO6LPP0/8XELEFhMTQz///DPZ2NgQAMqbNy/t27dP6bAyneTka9IkIjKsixcvolmzZqhbty5OnToFOzs7jB07Fvfu3cOoUaNgZ2endIiZgloNtGnDLYKnTwPLlnGLk7G2bgUiI4HRow0fz57dFFEa1qoVEBzMLW0Af33zBmjZMunnnjsHXLgAVK9uunjOnweiooDGjXWPFSgAlC3LLXYAd5G7u3PL5bt33BK4dCmQLx9QuXLCdYeEADlzJn5+Q2VWrwbu3uUWPkM+/5zjPnOG79+7B+zfz62UQhjLwsIC3377Lc6ePYuyZcvixYsXaNGiBQYNGoT3798rHZ5ZkgRQZDh37txB165dUalSJRw4cAD/b+/O46Kq9/+Bv1gVFAlEQRTFDcF9zyW/AqLmknbLyrreMNMWr169Ku4LbkTu3kpTy9Rfi94ss9WEZCyXWy6Ya7hhbigpOqC5gHx+f7wbZgZmZMDBA8zr+XicB845nznznpnSF5/P+XyOq6srXn/9dZw6dQpxcXF4pCQThQPaulUCwrp1QIsWEgjmzrX9+SdOyHVsNWrY1r5WLaByZfPt7NmC7SZMKNhOpzNv4+YGDBpkHMZdvVoeu7lZfu1OneQ87u5Au3bAs8/K0Ki9XLok5/bxMd/v728c3nVyAhISgORkwMsLqFgRWLwY2LLFeljevRv473+BV1+1/tobN8q1nS+9ZNx34oQM7370kVz/Z8nAgcDs2fK9u7kB9esDERHyPKKiat68Ofbs2YN///vfAIDly5ejdevW2Lt3r8aVOR4GQCoz0tLSMHz4cISFheGTTz4BADz//PM4duwYli1bhhq2JgwqkpQUufA/IMC4r31725+vlIQaW/30k0yeMN0CAwu2i4kp2M5Sb93LL0sv5KVL8nPIEOuvvWGDnOfXX+XPmzc/nKBj+hkpBQwfDlSvLp/FL7/IZI6+feX6xPyOHJHj06cD3btbPr9OBwweDKxaBTRpIvvu3QNeeEGudQwJsV6bTieBf9ky6RH9/HPg668lFBIVR8WKFbFo0SIkJCQgMDAQKSkp6NixI+Li4nDP9GJYKlFWfucjKj2uX7+O+fPnY8mSJXlDBY8//jji4uLQqlUrjasr/4oa4PILCZGhx7Q023oB69Yt2NNlqXfKz09m6hamaVMgNFRmzYaFyWNLs3MBCbqGc4aFyXDntGky+7dixcJfqzABATIcfu2aeS9gerr0PgIy8ePrr6VNlSqyb9ky6RVcu9Y8kB49CkRGAsOGAVOnWn7N7dtlyHvRIvPezKwsGeZOTgZGjJB9ubnyfbu6Ss9vZKS8/3/8Axg6VNo0ayZD06+8IpcCcG4VFVdUVBSOHj2KuXPnIjExERs3bsTJkycxe/Zs1LQ2U4vuqyiTHRkAqdS6desW3n77bbzxxhu4du0aAKBDhw544403EB4erm1xDiQ0VIZgL1+WoUpAhhJtNWCAhJZ582QoM7/r10v2OkBAev2GDweWLy/a81xc5Bq8u3ftEwDbtJFh1IQEGV4GJBgfPiyfDwAYLofK//e4s7MENIMjRySgRUdbH5LX6aTn8M03Cy7rU6UKcOiQ+b5lyySAbtwoQdxQT/5aXFwkKHI1D3pQ3t7emGf4j58eWFHuY88ASKVOTk4O1qxZg9jYWFz4axG3xo0bIy4uDv369YPTg3RHUZF17y7XfUVHS0jJyjJOArHlqwgKkuA3YgSQmSm9UMHBsvbdunVyzV1xloLJyjJeN2fg6WnsNTM1bBjwzDOFB82rV+WcOTkSjpYulevdTM9561bBHsTKlaXnMCNDwvLFi7I/JUV+BgTI5u0tQ9Jjx8pkD19fYNw46VUzLFHZsaP0DkZHy7Cuh4cM3aamGideHDkidfXoAYwZY/wcXFxkeRhAwl+fPsCoUcDTTxvbuLvL6zo7S2+oqerVJeia7jf0HrZqJUPsJ09Kr2C/fvJ6RFRG2XtaMVFx5ebmqk8//VSFhITkLelSu3ZttWbNGpWTk6N1eeWeLcvAuLsrFRqq1FdfSf+PYekSWyQkKNWzp1I+PkpVrCjnGTdOqYsX5XhRl4Ex9kEZt1dflePWlmExSE62vAyMYXNxUapWLaWGDVMqPd34vBkzLL9u165y/IMPLB+fMcN4jlu3lBoxQilfX6U8PJTq21eps2fN69uzR6kePaSNl5dSHToo9e23hddRp46xTXT0/Wu1xNIyMNnZSsXGKlW/vnxvQUGy5Iyl74mItGdrXnP6q/F9ZWZmwtvbG3q9HlUs/XpN9IASExMxadKkvJlgfn5+mDJlCl577TVUtMfYG9nVzp0yK/TkSekdJCKi0sHJycmmvMYhYNLUnj17MHnyZCQmJgKQ6xfGjh2LMWPG8JeNUmTTJhnmbNhQQt+oUXLHC4Y/IqKyifO3SBMpKSl45pln0L59eyQmJsLNzQ2jRo3CqVOnEBsby/BXymRlySSK0FBZTqRdO1kiBQDi4gqux2fYevXStGwiIrKCQ8D0UJ0/fx4zZ87EBx98gHv37sHJyQn/+Mc/MHPmTAQHB2tdHhVDRoZslnh4WL/vLhER2R+HgKlUycjIQHx8PN566y3cvn0bANCvXz/MnTsXTfNPRaQyxde38FuQEZFjCw8HWrYEliyRVQBGj5aNtMMhYCpRN2/eRFxcHOrVq4f58+fj9u3b6NKlC3bu3InNmzcz/BEROZg9ewquS/mgkpKA3r1leSVPT6BxY1lu6a+VxKDTybJV168XfG5wsART08dOTgW3+Hg5fuaMPHZ1NZ7fIC1N9js5STvT9obN3V2WjZozx3wtzdhYCcnWfP450LOnLILv5GR5Qfs7d6w/Pz8GQCoRd+/exbJly1C/fn1MmTIFer0ezZs3xzfffIPt27ejk+G2B0RE5FCqVZOQZi8rVsg6mgEBwGefyR1y3n1X7kBUnDVGAWDWLAlzptvIkeZtAgNlLVNTa9dav+wlMVHOc+KE3IJx7lzjfcptcfOmTL4zBFFLitKrygBIdpWbm4uPP/4YYWFh+Oc//4nLly+jXr16+Oijj5CcnIzevXtzIWciIgeWv8ftt99kWamKFaXnLjFReri++KLwc50/D/zrX7KtXi1DzcHBwP/9H/Dee7KYenF4eRkXcDdslSqZt4mOBj74wHzfmjWy35KqVeU8deoAf/+73P5x/37ba/rHP+T9GBaNz0+vB95/3/bzMQCSXSil8N1336F169b4+9//jtOnT8Pf3x/vvPMOjh07hhdeeKFI9ygkIqLyLzcXePJJ6RH8+Wdg5UrjnYZs8emncqvG8eMtHy/J20z26yf37N6xQx7v2CET4p54ovDn7t0r4e/RR+1Xz759QHa27e35LzI9sF27diE8PBy9e/fGr7/+iipVqmDOnDk4deoUhg8fDnd3d61LJCKiUmjrVuDUKRlKbdFCegKt3dvakhMn5FaNNWrY1r5WrYLLVZ09W7DdhAkF2+l05m3c3IBBg4zDuKtXy2M3N8uv3amTnMfdXZbSevZZuTWmvVy6JOe2FWcBU7EdPnwYU6ZMwZdffgkAqFChAkaOHImJEyeiatWqGldHRESlXUqK3C88IMC4r31725+vlG33JDf46ScZ3jUVHl6wXUyMrHlqytK1fS+/LPfvjouT3sjdu+Ve4pZs2ACEhUkv3aFDMmzt43P/a/pKEgMgFdnvv/+OGTNmYN26dVBKwdnZGUOGDMH06dMRFBSkdXlERFRGFDXA5RcSIte+paXZ1gtYt27BYWFXC0nIz09m6hamaVNZIP/55yXcNW1qeXYuIEHXcM6wMOD0aWDaNJn9a487ngYEyHC4rTgETDZLT0/H6NGjERISgrVr10IphaeffhpHjhzBqlWrGP6IiKhIQkNlCPbyZeO+PXtsf/6AATLsOW+e5eOWln2xtyFDZHh4yJCiPc/FRXoLixLa7qdNG+vDz5awB5AKlZmZiUWLFmHhwoW4ceMGACAyMhLx8fFo166dxtU5Bi6iSkTlUffuck/x6GgJcVlZxkkgtvQMBgUBixcDI0YAmZlyTV1wsMwOXrdOrrkrzlIwWVlyTZ0pT0+53jC/YcOAZ54pfMLJ1atyzpwcGQJeuhSIiDA/561bBXsQK1eWnsOMDAnLFy/K/pQU+WmYpeztLUPS775r23tkDyBZdefOHSxduhT169fHzJkzcePGDbRp0wYJCQn44YcfGP40osUiqrt3A61by1+K+fXpA3z0kfnj1q0LboblEi5elMft2gHp6ebn+uMP2d+6tfEvOUN7w9a+PdC/vyzxYLqI6ooVwMCB1t/jtm3AP/8JREbKeQx/eZq6exd4801p07mzhGzTngkA+P134N//ljZdugAvvWTeY3H9uvxj1LOnzPDr1Uuu8fnrd6c8u3bJP3qPPQZ06waMG2e+qGxyspw7IkKuMXrqKfPP2SArS87fowfQoQPw9NPGWYlEpZ2Liyz3cuOG/L8/dCgwdaocs3VYdPhwmUxy4QLwt79Jr+LQoRKsxo0rXl3Tp8uQsulmbaaxq6sMGVsaSjYVFSXnCQ6Wv8N795brAk0dPw60amW+DR0qx778Uh736SOPBw6Ux6aBb/Fi298j7wVMBdy7dw8ffvghpk+fjrN/TY8KCQnB3Llz8fTTT3MdPw2Y9gDa24oV8hdodLTxt+ezZ+W35ypVgEWLgHv35C9qIqKStnOn/GJ08qT0DlLR2HovYPYAUh6lFDZv3ozmzZtj8ODBOHv2LAIDA7Fy5UocOXIEAwYMYPgrBbRYRJXhj4hKyqZNQEKC3DItMVF6xzp3ZvgrabwGkAAAP/74IyZOnIjdu3cDAHx8fDBp0iSMGDECHh4eGldH1hgWUa1dWxZRzcqSoVtbabmIKhERIH9vjR8PnDsnQ6lRUcbr9uLiZLOkSxfgu+8eXp3lDQOggztw4AAmT56M7/76v8jDwwP//ve/ERMTg0f4r3+pZ1hEVaczrqM1d65cWG2Loi6iSkRkby++aH1B5NdekwWTLWHfxINhAHRQJ0+exPTp0/HJJ58AAFxdXTFs2DBMmzYNNZgGyoyHvYgqEdHD5OsrG9kfrwF0MGlpaRg+fDjCwsLywt/zzz+PY8eOYdmyZQx/ZYw9F1ElIiLHwQDoIK5fv44pU6agQYMGWL58OXJyctCrVy/s378fH3/8MRrYsuQ5lTpaL6IaHm5cjzD/5BQiIiq9GADLuVu3bmH+/PmoV68e4uLi8Oeff6JDhw7Q6XT49ttv0apVK61LpAdguojqwYOyfEJxFlFdulQWEN2+Xda527kTePVVYPZs22vRYn1CnU7ep6Wgmj+QBgdL2/yb4T6cZ87IY1dX8/X4AOkhdXWV42fOmLc3bO7usljrnDnm6xPGxsoSPtZ8/rmsGejnJ+exdBupO3eAkSOlTaVKQL9+MoPb1PHjsj6in59c19m5s3x+piy9//yLxioFLFggvcMVKsh/I/kvwn/nHbmVlYcH0KiRLBlkatUquUDfx0e2qCjgl1+sfwZE9PAxAJZTOTk5WLVqFRo2bIjx48fj2rVraNy4Mb744gvs2rULXbt21bpEsoPStIhqtWoS0uxlxQoJDgEBwGefAUePSljR64u3sj8AzJolYc50GznSvE1gYMFAs3at5RvBA7JsRVqaTKiZOVMm4axebXtNN29KWLvfDeFHj5alMtavl0Web9wA+vaV9RkN+vSROwxs2wbs2yehs2/fgncz+OAD8/cfHW1+fNQoWQJowQJZYuirr8yvK12+HJg0SYLtkSPynv/5T2lnoNPJvVGTkmQR8dq1ZaHq/MGaiOzrRv4V5+9H2UCv1ysASq/X29KcNJSbm6s+/fRTFRISogAoAKp27dpqzZo1KicnR+vy6CHYsUMpQKmTJ0v+tbp2VWrUKPlznTpKLV5sPHbsmFKdOytVoYJSYWFKJSRIXZs2FX7ec+eUcndXavRoy8evXZOfSUlyTsNjU/nryf84v9RUOdfUqUo1bGh+rFEjpaZNk+Opqebtk5PN20ZGKjV8uPHxjBlKtWhh/XXzv37+812/rpSbm1Lr1xv3XbiglLOzUlu2yOM//pDn/vijsU1mpuxLTDTuK+zzP3pUKVdXpX77zXqbjh2VGjfOfN+oUfJdW5OTo5SXl1Jr11pvQ0QPrih5jT2A5UhiYiLat2+PZ555BsePH4efnx+WLFmC48ePIzo6Gi5czbdcKo2LqBrWJ/T0lPUJV640Dk3bQsv1Cfv1A65dM95ObccOuQfnE08U/ty9e4H9++UWcPaybx+QnS09aAaBgUDTpnI7OUCGyMPCpOfy5k3pCVyxAvD3lxvEmxoxQoaJ27WTHtXcXOOxr74C6tUDvv4aqFtXhs2HDpX3b3DnTsHeZQ8PGeLNzrb8Hv78U45xNidR6cEAWA7s2bMHUVFR6N69O/bu3YvKlStjxowZOHXqFEaNGoUKFSpoXSKVoKwsGcYNDQUGD5Z/2DdvlmNxcXIjcUtbr14lV5NhfcJ164AWLeROJXPn2v78oq5PWKtWwff3110MzUyYULCdTmfexs0NGDTIOIy7erU8dnOz/NqdOsl53N3ls3/2WetrmhXHpUtybh8f8/3+/sbhXScn+SUgORnw8pKAtngxsGWLeViePVvCdWKi3Ed07Fjz6/tOn5ZrQD/9VL67NWskgA4YYGzTs6cMEe/bJ9cL7t0rn1F2NnDliuX3MHGiDKFHRdnjEyEie+A6gGVYSkoKpk6dio0bNwIA3NzcMHz4cEyePBnVq1fXuDp6WErjIqoPe33Cn36S4GMqPLxgu5gYCcmmLF3b9/LLQMeOEo4+/VSuY8vJsfzaGzZI71t2NnDokNxWz8fn/tf02YPpZ6SU/BJQvbp8Fh4eEtL69pXJOYYgbbg+FDBOTJk1y7g/N1d6+Natk0kgAPD++9KLmJIiEz6mTZPg2aGDvK6/v3ym8+ZZvmXgvHnAJ59I0Lb1ulQiKnkMgGXQ+fPnMXPmTHzwwQe4d+8enJyc8OKLLyI2NhbBwcFal0eliFaLqNpzfUJbegHr1i04LOxq4W83Pz+ZqVuYpk2lR/X55yXcNW1qeXYuIEHXcM6wMOlFmzZNJknYI/AEBMhw+LVr5r2A6enS+wjIxI+vv5Y2hvu/L1smvYJr10oPnCUdOgCZmbKMkL+/fNaursbwZ3hPgPSoNmok4XL1ahlivnxZnrNypQRwPz/z8y9YICE6MRFo3vzBPwsish8OAZchV69eRUxMDBo0aID33nsP9+7dQ79+/XDw4EGsWbOG4Y9KDa3XJ7SHIUOk12rIkKI9z8VFegvv3rVPHW3ayPBzQoJxX1oacPiwMQD++af8dM73N7qzs/k1fvklJ0tINYTnzp2l9lOnjG2OH5efdeqYP9fNTYbeXVxkdnLfvuavP3++DDlv2QK0bWvz2yWih4Q9gGXAzZs3sWTJEsybNw+ZmZkAgC5duiA+Ph6dDP8CEJUipusTzpsn1ykWZ33CESOkh+rFF2VCwvnzMjxZuXLxloLJyiq4LIqnp7HXzNSwYcAzzxQ+4eTqVTlnTo4MAS9dCkREmJ/z1q2CPYiVK0vPYUaGhOWLF2V/Sor8DAiQzdtbhqTHjpXJHr6+sjxPs2bGa+o6dpTewehoYPp06aVbtQpITZXlYQCZ4HHpkrT18JAlWqZMkUlDhsuEo6KA1q0l9C5ZIuHxn/+U79PQK3j8uEz4ePRR6XFctEjC6Nq1xvc2b570gn78sXxvhs/ccN0lEZUC9p5WTPZz584d9c477yh/f/+8JV1atGihvv32W5Wbm6t1eUQ2LQPj7q5UaKhSX30ly5AYli6xRUKCUj17KuXjo1TFinKeceOUunhRjhd1GRgZnDbfXn1VjltbhsUgOdnyMjCGzcVFqVq1lBo2TKn0dOPzZsyw/Lpdu8rxDz6wfHzGDOM5bt1SasQIpXx9lfLwUKpvX6XOnjWvb88epXr0kDZeXkp16KDUt98aj3/3nVItWypVubJSnp5KNW2q1JIlSmVnm5/nwgWlnnpK2vn7KzV4sFJXrxqPHz0q5/HwUKpKFaX69y+4bIy1z9r0PRGR/RUlrzkpZbpmvWWZmZnw9vaGXq9HFUu/KpNd5ebmYv369Zg2bRpOnz4NAKhXrx5mz56NgQMHwjn/OA9RGbBzp8wGPnlS2yVqiIjKq6LkNQ4BlyJKKXz33XeYPHkyfv31VwCAv78/pk+fjqFDh8Ld3V3jColst2mTDPc1bCihb9Qo7dcnJCIiwa6kUmLXrl0IDw9Hnz598Ouvv6JKlSqYM2cOTp06heHDhzP8UZlTGtcnJCIiwSFgjZ08eRLvvPMOtm/fDgBwd3fHwIEDMXjwYDxSkrc7INJQRob53SVMeXhYv+8uERFZV5S8xgBIREREVA4UJa9xCJiIiIjIwTAAEhERETkYBkAiuq/s7GytSyAiIjtjACSi+/rkk09w69YtrcsgIiI7YgAkIqv0ej3Gjh2LRo0aYcOGDVqXo6msrCy8+OKLaN26NSIjI3HixAmtSyIiKjYGQCKyKi4uDleuXIGnpyeeeuoprcvRlJeXF/7zn//A1dUVSUlJ6NixIw4ePKh1WURExVKqA2B4ODB6tPw5OFhuTk5ED8eZM2ew5K//6RYsWAA3NzdtCyoFHnnkEWzduhXt2rXD1atX0a1bNxw6dEjrsoiIiqxUB0BTe/YAr7xi33MmJQG9ewNVqwKenkDjxsDYscCFC3JcpwOcnIDr1ws+N38gDQ6Wtvm3+Hg5fuaMPHZ1NZ7fIC1N9js5STvT9obN3R1o0ACYM0duq24QGwu0bGn9PX7+OdCzJ+DnJ+c5cKBgmzt3gJEjpU2lSkC/fsD58+Zt9u8HuncHHnlEPq9XXgFu3Ch4rjVrgObNgYoVgYAAYMQI8+OHDgFduxoX+501y/z9AMD27UCbNnKOevWAd98t+J7atpVaKlWS9////p/1z4CKZ9KkSbh79y4iIyPRp08frcspNQwhsG3btrhy5QoiIyMZAomozCkzAbBaNQlp9rJiBRAVJSHls8+Ao0claOj1wMKFxTvnrFkS5ky3kSPN2wQGAuvWme9bu9b6nQ8SE+U8J04AM2cCc+cCq1fbXtPNm3L/VUMQtWT0aLlv6/r1wI4dEuz69gXu3ZPjFy/KZ9WgAfDzz8CWLcCRI3J7L1OLFgFTpgATJ8rxH36Q8GmQmSkhMjBQAv1bbwELFsjzDFJTJZR36QIkJwOTJwP/+pd8Rwa+vvI6u3cDBw8CL70k2/ff2/650P39/PPPWL9+PZycnLBw4UI4OTlpXVKpYikEHj58WOuyiIhsp2yg1+sVAKXX621pbjdduyo1apT8uU4dpRYvNh47dkypzp2VqlBBqbAwpRISlAKU2rSp8POeO6eUu7tSo0dbPn7tmvxMSpJzGh6byl9P/sf5pabKuaZOVaphQ/NjjRopNW2aHE9NNW+fnGzeNjJSqeHDjY9nzFCqRQvrr5v/9fOf7/p1pdzclFq/3rjvwgWlnJ2V2rJFHq9YoVT16krdu2dsk5ws5ztxQh5nZCjl4aFUYqL1GpYtU8rbW6nbt4373nhDqcBApXJz5fH48UqFhpo/79VXlerQ4f7vr1Ur+WzpweXm5qpOnTopAGrw4MFal1OqZWRkqDZt2igAys/PTx06dEjrkojIgRUlr5WZHkBTubnAk09Kj+DPPwMrV0qPkK0+/RS4excYP97y8ZK8BW+/fsC1a9LTBsjPjAzgiScKf+7evTIU++ij9qtn3z4gOxvo0cO4LzAQaNoU2LVLHt+5I0PQzib/tXh4GOsHgIQE+V4uXADCwoBatYBnnwXOnTM+Z/duGf6tUMG4r2dP6WE0DH3v3m1ei6HN3r1SZ35KSU9jSgrwf/9XrI+A8vnss8+wa9cueHp6Ys6cOVqXU6r5+PggISEBbdq0YU8gEZUpZTIAbt0KnDolQ6ktWgCPPSZDo7Y6cQKoUgWoUcO29rVqAZUrm29nzxZsN2FCwXY6nXkbNzdg0CDjMO7q1fLY2vX1nTrJedzdgXbtJFS9+KLNb7VQly7JuX18zPf7+8sxAIiMlD/Pny/B+do1GZoFZHgaAE6flgAYFyfXRm7cKMG2e3d5juG1/P0Lvo7h2P3a5OQAV64Y9+n1xs+lTx8ZTu7e/YE+CgJw584djP/rN6OYmBjUtHZtAuUxhMDWrVvjjz/+QGRkJI4cOaJ1WURE9+WqdQHFkZICBAXJ9XsG7dvb/nylZEKErX76CfDyMt8XHl6wXUxMweviLP37+fLLQMeOEpY+/VR6vXJyLL/2hg3So5adLRMo/vUvCWv3u6bPHkw/oyZN5DrFMWOASZMAFxepw99f/gxI+MvOBv7zH2MP3iefyHeUlGS8FjD/526YAGK635Y2Xl4yoeXGDekBHDNGJoxY+l7Idm+//TZSU1NRo0YNxMTEaF1OmeHj44PExERERUVh//79iIyMxLZt29CkSROtSyMisqhMBsCiBrj8QkKkByktzbZewLp1Cw4Lu1r45Pz8ZKJEYZo2BUJDgeefl3DXtKnl2bmABF3DOcPCpKdt2jSZ/VuxYuGvVZiAAGOvnmkvYHq69D4avPCCbJcvy8xbJyeZvFG3rhw3fI6NGxufU62afCaG3tKAAGNPn+nrAMZeP2ttXF1l9rGBs7Pxc2nZEjh2DHjjDQbAB3H16tW8Id85c+agUqVKGldUthh6AqOiopCcnIzIyEgkJSWhsen/FEREpUSZHAIODZVQcfmycd+ePbY/f8AAGTqcN8/ycUvLvtjbkCEyPDxkSNGe5+IivYWGYdUH1aaNDD8nJBj3paUBhw+bB0ADf38Zet2wQQKoYdi1c2f5mZJibJuRIcO2derI444dgR9/NK9961a55jA42NjGtBZDm7ZtrQ+TA/JLwZ07Nr1lsmLWrFm4fv06mjdvjujoaK3LKZN8fX2RmJiIVq1aIT09HRERETh69KjWZRERFVAmewC7dwfq1weioyXEZWUZJ4HY0jMYFAQsXixr1GVmyjV1wcGy9t26dRJwirMUTFZWwd4rT0+53jC/YcOAZ54pfMLJ1atyzpwcGQJeuhSIiDA/561bBXsQK1eWHrKMDAnLFy/KfkNACwiQzdtbhqTHjpUeNl9fYNw4oFkzWfrF4O23jdcjJiTIcHd8vLH+kBCgf39g1CiZlFOligwXh4ZKvYD0IM6cKcPkkyfLtZhxccD06cbv7bXX5LXGjJHPaPdu4P33ZTjZ4I03JBDWry9h8ttv5Xtbvvz+nyVZd/z4cSxbtgwAsHDhQrgYxvapyAwh0LQncNu2bewJJKLSxd7Tiu3JlmVg3N1l2ZCvvpJlSQxLl9giIUGpnj2V8vFRqmJFOc+4cUpdvCjHi7oMjPRDmW+vvirHrS3DYmBYViX/MjCGzcVFqVq1lBo2TKn0dOPzZsyw/Lpdu8rxDz6wfHzGDOM5bt1SasQIpXx9ZSmXvn2VOnvWvL5//EOOu7sr1by5UuvWFXwPer1SQ4Yo9cgj0vZvfyt4noMHlerSRZbvCQhQKjbWuASMgU4ny7q4uysVHKzU8uXmx6dMUapBA/nOfHyU6tjRfBkbKrr+/fsrAKp3795al1JuXL16VbVs2VIBUP7+/uro0aNal0RE5VxR8pqTUvnvw1BQZmYmvL29odfrUcVSd1YpsHOnzAY+eVJ6hojINtu3b0d4eDhcXFxw8OBB9lTZ0dWrVxEVFYUDBw7A398fSUlJCAsL07osIiqnipLXyuQ1gIDcuSIhQdaPS0yUW5N17szwR1QUubm5GDNmDADglVdeYfizs6pVqyIxMREtWrTA5cuXERERgd9++03rsoiIym4AzMoChg+Xa8wGD5Y18jZvlmNxcQXX4zNsvXppWjZRqfLRRx9h//798PLyQmxsrNbllEsMgURUGpWbIWBTGRmyWeLhYf2+u0SO5M8//0SjRo1w/vx5vPHGG5g4caLWJZVrV65cQbdu3XDw4EEEBAQgKSkJoaGhWpdFROVIUfJamZwFXBhfX9mIyLpFixbh/PnzqF27NkaPHq11OeWen58ffvjhh7wQGBERAZ1Oh0aNGmldGhE5oDI7BExExXfp0iXE/3U7mfj4eFS0x6riVChDCGzWrBkuXbqEiIgIpJgunklE9JAwABI5oOnTp+PmzZto3749Bg4cqHU5DsU0BKalpSEiIgLHjx/XuiwicjAMgEQO5vDhw3j//fcByDCw04PcV5GKpVq1amYhMDw8nCGQiB4qBkAiBzNu3Djk5ubi6aefRmfDPfzooTOEwKZNm+b1BJ44cULrsojIQTAAEjmQLVu24Pvvv4ebmxvefPNNrctxeKYh8OLFiwgPD2cIJKKHggGQyEHk5ORg3LhxAICRI0eiPldNLxWqV6+OH374AU2aNMHFixfZE0hEDwUDIJGDWL16NY4cOQJfX19MnTpV63LIRPXq1bFt2zY0adIEFy5cQEREBE6ePKl1WURUjjEAEjmArKwsTJs2DYDMAPbx8dG4IsrPEAIbN26MCxcuIDw8nCGQiEoMAyCRA3jzzTeRnp6OBg0a4PXXX9e6HLIifwhkTyARlRQGQKJy7ty5c1i4cCEAYN68eXB3d9e4Iroff3//vBB4/vx5RERE4NSpU1qXRUTlDAMgUTk3efJk3L59G126dMGTTz6pdTlkA0MIDAsLw/nz5xEeHs4QSER2xQBIVI7t3bsXH374IQAu+lzWGEJgaGhoXk/g6dOntS6LiMoJBkCickophbFjxwIABg0ahLZt22pcERVVQEAAkpKSEBoainPnziE8PJwhkIjsggGQqJzavHkzfvzxR1SsWBFxcXFal0PFxBBIRCWBAZCoHLp79y7Gjx8PABgzZgyCgoI0rogeREBAALZt24ZGjRrh3LlziIiIQGpqqtZlEVEZxgBIVA4tX74cJ06cQPXq1TFx4kStyyE7qFGjBpKSktCoUSOcPXsW4eHhDIFEVGwMgETlzLVr1zBr1iwAwOzZs+Hl5aVxRWQvhhAYEhKCs2fPIiIiAmfOnNG6LCIqgxgAicqZOXPmICMjA02aNMGQIUO0LofsrEaNGtDpdAgJCcHvv/+O8PBwhkAiKjIGQKJy5NSpU3jrrbcAAAsWLICrq6vGFVFJMO0JZAgkouJgACQqRyZOnIjs7Gz06NEDjz/+uNblUAkKDAxEUlISGjZsiN9//x0RERH4/ffftS6LiMoIBkCicmLHjh3YuHEjnJ2dsWDBAq3LoYcgMDAQOp0ODRs2xJkzZxAeHs4QSEQ2YQAkKgdyc3PzFn0eMmQImjVrpnFF9LCY9gQyBBKRrRgAicqBDRs24JdffkGlSpUwe/Zsrcuhh6xmzZpISkpCgwYNcObMGURERODs2bNal0VEpRgDIFEZd/v2bUyaNAmAXAMYEBCgcUWkBdMQmJqaivDwcIZAIrKKAZCojFu6dCl+//131KxZE2PGjNG6HNJQrVq1kJSUhPr16zMEEtF9MQASlWHp6emYO3cuACAuLg6enp4aV0Raq1WrFnQ6XV4IjIiIwLlz57Qui4hKGQZAojIsNjYWWVlZaN26NQYNGqR1OVRKGHoC69Wrh9OnTyM8PJwhkIjMMAASlVHHjh3DypUrAQALFy6EszP/dyajoKAg6HS6vBDInkAiMsV/MYjKqJiYGNy7dw/9+/dHeHi41uVQKWQaAk+dOoWIiAicP39e67KIqBRgACQqgxITE/HNN9/A1dUV8+bN07ocKsWCgoKQlJSEunXr4tSpUwgPD2cIJCIGQKKy5t69e3mLPr/++usICQnRuCIq7WrXrg2dTpcXAiMiInDhwgWtyyIiDTEAEpUxa9euxcGDB+Ht7Y3p06drXQ6VEaYh8OTJkwgPD2cIJHJgDIBEZciNGzcwdepUAMC0adPg5+encUVUltSuXRtJSUkIDg5mCCRycAyARGXIggULkJaWhnr16mHEiBFal0NlUJ06daDT6fJCIIeDiRwTAyBRGXHx4kXMnz8fABAfH48KFSpoXBGVVXXq1MnrCTxx4gQiIiJw8eJFrcsiooeIAZCojJg6dSr+/PNPdOrUCQMGDNC6HCrjgoODkZSUhDp16uDEiRMIDw9nCCRyIAyARGXAgQMHsGbNGgCy6LOTk5O2BVG5EBwcDJ1OlxcC2RNI5DgYAIlKOaUUxo4dC6UUnnvuOXTo0EHrkqgcMYTA2rVr4/jx44iIiEBaWprWZRFRCWMAJCrlvvnmG2zbtg0VKlRAfHy81uVQOcQQSOR4GACJSrHs7GzExMQAAEaNGoXg4GBtC6Jyq27dunkhMCUlhSGQqJxjACQqxVatWoXffvsNfn5+mDx5stblUDlXt25dJCUlISgoCCkpKYiMjMSlS5e0LouISgADIFEppdfrMWPGDABAbGwsvL29Na6IHEG9evWg0+kQFBSE3377DREREQyBROUQAyBRKRUXF4crV66gUaNGeOWVV7QuhxxIvXr18noCf/vtN/YEEpVDDIBEpdCZM2ewZMkSAHL3Dzc3N20LIodTv359JCUloVatWjh27BgiIyNx+fJlrcsiIjthACQqhSZNmoS7d+8iMjISffr00bocclD169eHTqfLC4EREREMgUTlBAMgUSnzv//9D+vXr4eTkxMXfSbNsSeQqHxiACQqRZRSGDNmDAAgOjoaLVu21LYgIgANGjRAUlISatasiaNHjyIyMhLp6elal0VED4ABkKgU2bhxI3bv3g1PT0/MmTNH63KI8jRo0AA6nS4vBEZERDAEEpVhDIBEpcSdO3cwYcIEAEBMTAxq1qypcUVE5gw9gYGBgewJJCrjGACJSom3334bqampqFGjRt7dP4hKm4YNG0Kn0yEwMBBHjhxBt27dGAKJyiAGQKJS4MqVK5g9ezYAYM6cOahUqZLGFRFZZxoCDx8+jG7duuGPP/7QuiwiKgIGQKJSYNasWdDr9WjevDmio6O1LoeoUA0bNkRSUhJq1KiBw4cPIzIykiGQqAxhACTS2PHjx7F8+XIAwMKFC+Hi4qJxRUS2CQkJgU6nywuB7AkkKjsYAIk0Nn78eOTk5KB3796IiorSuhyiIgkJCcnrCTx06BC6deuGK1euaF0WERWCAZBIQ9u3b8fmzZvh4uKC+fPna10OUbE0atTILARGRkYyBBKVcgyARBrJzc3NW/T5lVdeQePGjTWuiKj4DCEwICCAPYFEZQADIJFGPvroI+zfvx9eXl6IjY3VuhyiB2YaAg8ePIioqChcvXpV67KIyAIGQCIN/Pnnn5g0aRIAYPLkyahevbrGFRHZR2hoKJKSkuDv749ff/0V3bp1YwgkKoUYAIk0sGjRIly4cAG1a9fG6NGjtS6HyK5CQ0Oh0+kYAolKMQZAoofs0qVLiI+PBwDEx8ejYsWKGldEZH/5ewI5HExUujAAEj1k06dPx82bN9G+fXsMHDhQ63KISkxYWBi2bdsGf39/HDhwAN27d0dGRobWZRERGACJHqpDhw7h/fffByDDwE5OThpXRFSyGjdujG3btqF69epITk5GVFQUQyBRKcAASPQQjRs3Drm5uXj66afRuXNnrcsheigaN26MpKQkhkCiUoQBkOgh2bJlC7Zu3Qo3Nze8+eabWpdD9FAZegKrVauG5ORkDgcTaYwBkOghyMnJwbhx4wAAI0eORP369TWuiOjha9KkCZKSklCtWjXs378f3bt3x7Vr17Qui8ghMQASPQSrV6/GkSNH4Ovri6lTp2pdDpFm8ofAqKgohkAiDTAAEpWwrKwsTJs2DYDMAPbx8dG4IiJtNWnSJG84mD2BRNpgACQqYfHx8UhPT0eDBg3w+uuva10OUanQtGlTbNu2DX5+fti3bx969OiB69eva10WkcNgACQqQefOncOiRYsAAPPmzYO7u7vGFRGVHqYhcO/evejevTtDINFDwgBIVIImT56M27dvo0uXLnjyySe1Loeo1GnWrBlDIJEGGACJSsjevXvx4YcfAuCiz0T306xZM/zwww+oWrUq9u7dy+FgooeAAZCoBCilMHbsWADAoEGD0LZtW40rIirdmjdvjm3btqFq1arYs2cPevbsCb1er3VZROUWAyBRCfjiiy/w448/omLFioiLi9O6HKIyoXnz5nk9gb/88gt69OjBEEhUQhgAiezs7t27GD9+PABgzJgxCAoK0rgiorKjRYsWDIFEDwEDIJGdLV++HCdPnkT16tUxceJErcshKnMMIdDX1xe//PILh4OJSgADIJEdXbt2DbNmzQIAzJ49G15eXhpXRFQ2mYbAn3/+GY8//jgyMzO1Louo3GAAJLKjOXPmICMjA02aNMGQIUO0LoeoTGvZsmVeCPzf//6Hnj17MgQS2QkDIJGdnDp1Cm+99RYAYMGCBXB1ddW4IqKyr2XLlkhMTISPjw9DIJEdMQAS2cmECROQnZ2NHj164PHHH9e6HKJyo1WrVvjhhx/yQiCHg4keHAMgkR3s2LEDn332GZydnbFgwQKtyyEqd1q1apXXE7h792706tWLIZDoATAAEj2g3NzcvEWfX375ZTRr1kzjiojKp9atW+eFwF27dqFXr17IysrSuiyiMokBkOgBbdiwAb/88gsqV66cNwOYiEqGIQQ+8sgj2LVrFx5//HGGQKJiYAAkegC3bt3KW+tvwoQJCAgI0LgiovIvfwhkTyBR0TEAEj2ApUuX4uzZs6hZsybGjBmjdTlEDqNNmzZISEjAI488gp07d6J3794MgURFwABIVEzp6el59/mNi4uDp6enxhUROZa2bdvmhcAdO3YwBBIVAQMgUTHFxsYiKysLrVu3xqBBg7Quh8ghGUKgt7d3Xgi8ceOG1mURlXoMgETFcOzYMaxcuRIAsHDhQjg7838lIq0wBBIVHf/VIiqGmJgY3Lt3D/3790d4eLjW5RA5vHbt2uWFwJ9++gl9+vRhCCS6DwZAoiJKTEzEN998A1dXV8ybN0/rcojoL+3atcPWrVtRpUoV/PjjjwyBRPfBAEhUBPfu3ctb9Pn1119HSEiIxhURkan27dsjISHBLATevHlT67KISh0GQKIiWLt2LQ4ePAhvb29Mnz5d63KIyIL27dsX6AlkCCQyxwBIZKMbN25g6tSpAIBp06bBz89P44qIyJpHH300LwRu376dIZAoHwZAIhstWLAAaWlpqFevHkaMGKF1OURUiEcffRTff/89vLy8sH37dvTt25chkOgvDIBENrhw4ULehI/4+HhUqFBB44qIyBYdOnTAjh078Nhjj0Gv12PMmDG4deuW1mURac5V6wKIyoKpU6fi1q1b6NSpEwYMGKB1OURUBM2bN8dPP/2kdRlEpQp7AIkKceDAAaxduxaALPrs5OSkcUVEREQPhgGQ6D6UUhg7diyUUnjuuefQoUMHrUsiIiJ6YAyARPfxzTffYNu2bahQoQLi4+O1LoeIiMguGACJrMjOzsa4ceMAAKNGjUJwcLC2BREREdkJAyCRFStXrkRKSgr8/PwwefJkrcshIiKyGwZAIgv0ej1iY2MBALGxsfD29ta2ICICAISHA6NHy5+Dg4ElS7SrhagsYwAksiAuLg5XrlxBo0aN8Morr2hdDhFZsGcPYO//PZOSgN69gapVAU9PoHFjYOxY4MIFOa7TAU5OwPXrBZ+bP5AGB0vb/JvhcuIzZ+Sxq6vx/AZpabLfyUnambY3bO7uQIMGwJw5gFLG58bGAi1bWn+Pn38O9OwJ+PnJeQ4cKNjmzh1g5EhpU6kS0K8fcP68eZvjx4H+/aVNlSpA587y+Rn8+ivw/PNAUBDg4QGEhQFLl5qfQ6eTc9SoIa/TsiXw0UfWa9+5Uz6X/O8vOxuYNQuoXx+oWBFo0QLYssX6eYgBkKiAM2fOYMlff4svWLAAbm5u2hZERBZVqyYhzV5WrACiooCAAOCzz4CjR4F33wX0emDhwuKdc9YsCXOm28iR5m0CA4F168z3rV0L1Kxp+ZyJiXKeEyeAmTOBuXOB1attr+nmTQlr95vXNno0sGkTsH49sGMHcOMG0LcvcO+esU2fPkBODrBtG7Bvn4Syvn2BS5fk+L598h19+CFw5AgwZQowaRLw9tvGc+zaBTRvLp/3wYPAkCHAiy8CX31VsCa9Xo5161bw2NSp8v299ZZ8b6+9Bvztb0Bysu2fi8NRNtDr9QqA0uv1tjQnKtMGDhyoAKjIyEiVm5urdTlEZKJrV6VGjZI/16mj1OLFxmPHjinVubNSFSooFRamVEKCUoBSmzYVft5z55Ryd1dq9GjLx69dk59JSXJOw2NT+evJ/zi/1FQ519SpSjVsaH6sUSOlpk2T46mp5u2Tk83bRkYqNXy48fGMGUq1aGH9dfO/fv7zXb+ulJubUuvXG/dduKCUs7NSW7bI4z/+kOf++KOxTWam7EtMtP6aw4crFRFx/7p691bqpZcK7n/uOfmsLL2/GjWUevtt8339+yv197/f/7XKm6LkNfYAEpn43//+h/Xr18PJyYmLPhOVIbm5wJNPSo/gzz8DK1dKj5OtPv0UuHsXGD/e8vFHHrFHlZb16wdcuyY9bYD8zMgAnnii8Ofu3Qvs3w88+qj96tm3T4ZUe/Qw7gsMBJo2lR47QIbIw8Kk5/LmTekJXLEC8PcH2rSxfm69HvD1vf/rW2rzwQfAqVPAjBmWn3Pnjgz9mvLwMH6mVBBvBUf0F6UUxowZAwCIjo5Gy/tdRENEpcrWrRIQdDoZwgVkaLR7d9uef+KEXMdWo4Zt7WvVKrjvzz8L7pswQYYnTX39tUxmMXBzAwYNkmHcxx6Tn4MGyX5LOnUCnJ0lsGZny3WQL75oW922uHRJri/08THf7+9vHN51cgISEuT6PS8vqcffX667sxaWd+8G/vtf4JtvrL/2xo1ybeeKFcZ9J04AEycCP/0k1/9Z0rMnsGgR8H//J9cB/vADsHmz+ZA1mWMAJPrLxo0bsXv3bnh6emLOnDlal0NERZCSIpMNDOEPANq3t/35SkmosdVPP0nwMWUa6gxiYoDBg833Wbq27+WXgY4dgbg46Y3cvVt61SzZsEF637KzgUOHgH/9S8JaSa9Vb/oZKQUMHw5Ury6fhYcH8N57cg3gnj0Fg/SRIxIWp0+3Hsp1OvmsVq0CmjSRfffuAS+8INc6hoRYr23pUmDYMCA0VGqsXx946SXpOSTLGACJANy5cwcTJkwAAMTExKCmtauviahUKmqAyy8kRIYe09Js6wWsW7dgT5el3ik/P5mpW5imTSW8PP+8hLumTS3PzgUk6BrOGRYGnD4NTJsms3/zD4MWR0CA9C5eu2beC5ieLr2PgEz8+PpraVOliuxbtkx6BdeulR47g6NHgchICWj5e0MNtm+XIe9Fi8x7M7OyZJg7ORkYMUL25ebK9+3qKj2/kZEy2eSLL4Dbt4GrV2XIeuJE+Z7IMl4DSATg7bffRmpqKmrUqIGYmBityyGiIgoNBc6eBS5fNu7bs8f25w8YIMOe8+ZZPm5p2Rd7GzJEesGGDCna81xcpLfw7l371NGmjQw/JyQY96WlAYcPGwOgYbjbOV+KcHaWgGZw5AgQEQFER8uQvCU6ncwojo8vuKxPlSrSy3nggHF77TWgUSP5c/5rHytWlB7WnByZWdy/f5HeukNhDyA5vCtXrmD27NkAgDlz5qBSpUoaV0RERdW9uwz7RUdLiMvKMk4CsaVnMCgIWLxYepkyM6UXKjhY1r5btw6oXLl4S8FkZRmvmzPw9DT2mpkaNgx45pnCJ5xcvSrnzMmRcLR0qYQs03PeulWwB7FyZek5zMiQsHzxouxPSZGfAQGyeXvLkPTYsTLZw9cXGDcOaNZMlskBZLjax0c+7+nTZQh41SogNVXCHGAMfz16AGPGGD8HFxfpsQOM4W/UKODpp41t3N3ldZ2dpTfUVPXqEvRM9//8s6yl2LKl/IyNlSBqbVIPsQeQCLNmzYJer0fz5s0RHR2tdTlEVAwuLjIEeOMG0K4dMHSocbjR1mHR4cNlSPHCBVlDLjRUzlOligSg4pg+XYaUTTdrocTVVYaMrU10MIiKkvMEB0uPWe/ecl2gqePHgVatzLehQ+XYl1/KY0NQGzhQHr/7rvH5ixfLrOpnn5U1Az09ZW0+Fxc57ucnEz5u3JAh2LZtZcbt5s2yCDMg1zL+8Ycs7Gz6/tu1M77OmjXSm/jGG+ZtnnrKhg/XxO3b8n03bizfXc2aUk9Jzt4u65yUMl0/3LLMzEx4e3tDr9ejiqVfW4jKqOPHj6NJkybIyclBQkICogy/3hJRmbdzp8yqPXlSegeJyrui5DUOAZNDGz9+PHJyctC7d2+GP6IybtMmGeZs2FBC36hR0nvF8EdUEIeAyWHpdDps3rwZLi4umD9/vtblENEDysqSYdzQUFlOpF07GZIEZHmVypUtb716aVo2kSY4BEwOKTc3F+3atcP+/fvx+uuvY9myZVqXREQlKCNDNks8PKzfd5eoLOEQMFEhPvzwQ+zfvx9eXl6IjY3VuhwiKmG+voXfgozIkTAAksO5desWPv74Y7Rq1QojR45E9erVtS6JiIjooWIAJIfj4eGBLVu2aF0GERGRZjgJhIiIiMjBMAASERERORgGQCIiIiIHwwBIRERE5GAYAImIiIgcDAMglajwcGD0aPlzcDCwZIl2tRAREZFgAKSHZs8e4JVX7HvOpCSgd2+galXA0xNo3BgYOxa4cEGO63SAkxNw/XrB5+YPpMHB0jb/Fh8vx8+ckceursbzG6SlyX4nJ2ln2t6wubsDDRoAc+YApvffiY0FWra0/h4//xzo2RPw85PzHDhQsM2dO8DIkdKmUiWgXz/g/HnjccPnYGnbs0farFljvU16uvE8/fsDNWrI67RsCXz0UcF6tm8H2rQBKlYE6tUD3n3X+vtbv15e48knrbchIiL7YgCkh6ZaNQlp9rJiBRAVBQQEAJ99Bhw9KkFDrwcWLizeOWfNkjBnuo0cad4mMBBYt85839q11m8llZgo5zlxApg5E5g7F1i92vaabt6UG9obgqglo0cDmzZJmNqxA7hxA+jbF7h3T4536lTwfQ0dKqG3bVtp89xzBdv07Al07QoY1sretQto3lw+74MHgSFDgBdfBL76ylhLaqqE8i5dgORkYPJk4F//kufk9/vvwLhx0paIiB4iZQO9Xq8AKL1eb0tzojxduyo1apT8uU4dpRYvNh47dkypzp2VqlBBqbAwpRISlAKU2rSp8POeO6eUu7tSo0dbPn7tmvxMSpJzGh6byl9P/sf5pabKuaZOVaphQ/NjjRopNW2aHE9NNW+fnGzeNjJSqeHDjY9nzFCqRQvrr5v/9fOf7/p1pdzclFq/3rjvwgWlnJ2V2rLF8rnu3lWqenWlZs2y/nrp6XLedevuX1fv3kq99JLx8fjxSoWGmrd59VWlOnQw35eTI9//e+8pFR2tVP/+938dIiK6v6LkNfYAkiZyc2XIz9MT+PlnYOVKYMoU25//6afA3bvA+PGWjz/yiD2qtKxfP+DaNelpA+RnRgbwxBOFP3fvXmD/fuDRR+1Xz759QHY20KOHcV9gINC0qfTYWfLll8CVK8DgwdbPu26dfD8DBtz/9fV683us7t5tXgsgPYl790qdBrNmSa/wyy/f//xERGR/DICkia1bgVOnJGS0aAE89pgMjdrqxAmgShW5Fs0WtWoBlSubb2fPFmw3YULBdjqdeRs3N2DQIOMw7urV8tjNzfJrd+ok53F3B9q1A559VoZN7eXSJTm3j4/5fn9/OWbJ++9LKAsKsn7e1auBF14APDyst9m4Ua4hfOkl83r8/QvWkpMjoRMAdu6UGlatsn5uIiIqObwXMGkiJUXCR0CAcV/79rY/XymZOGCrn34CvLzM94WHF2wXE1OwV8zStX0vvwx07AjExUlv5O7dEnAs2bABCAuT3q9Dh+R6OB+f+1/TZw/WPqPz54Hvvwf++1/rz929W66pzH+toymdTj6rVauAJk3Mj+V/XcOkFycnICtLAvOqVTJphYiIHj4GQNJEUQNcfiEhMvSYlmZbL2DdugWHhV0t/Nfv5yczdQvTtCkQGgo8/7yEu6ZNLc/OBSToGs4ZFgacPg1MmyazfytWLPy1ChMQIMPh166Z9wKmp0vvY34ffCCzpvv1s37O996TGb5t2lg+vn27DHkvWlSwNzMgoGDPY3q6fN5VqwJHjsgMadMh89xc+enqKr8c1K9vvTYiInpwHAImTYSGyhDs5cvGfYblSGwxYIAMe86bZ/m4pWVf7G3IEOkFGzKkaM9zcZHewrt37VNHmzYy/JyQYNyXlgYcPlwwAColAfDFF60PWd+4Ib2D1q7N0+mAPn2kB9PSsj4dO5rXAsiQf9u28pqhodITeuCAcevXD4iIkD/fb1iaiIjsgz2ApInu3aWXJzpaQlxWlnESiC09g0FBwOLFwIgRQGamBJrgYBneXLdOrrkrzlIwWVkFe688PeV6w/yGDQOeeabwCSdXr8o5c3Ik+CxdKmHH9Jy3bhXsQaxcWXoOMzIkLF+8KPtTUuRnQIBs3t4S1saOlR42X19ZWqVZM1kmx9S2bbJMy/0mXmzYILX+/e8FjxnC36hRwNNPGz8rd3fjRJDXXgPefhsYM0Y+o9275Xq/Tz6R4xUrSo+pKcNnmH8/ERGVDPYAkiZcXIAvvpDepnbtZE26qVPlmK3DosOHS8/ShQvA3/4mPUtDh0qwGjeueHVNny5DyqabtZnGrq4yZGxpKNlUVJScJzhYesx695aQZer4caBVK/Nt6FA59uWX8rhPH3k8cKA8Nl1cefFimVX97LOyZqCnp6zN5+Ji/jrvvy+9gmFh1ut9/33gqacKTioBZLHoP/8E3njD/DN66iljm7p1gW+/lbDYsiUwezbwn/9IYCQiotLBSSnTexJYlpmZCW9vb+j1elSx1BVCZAc7d8ps4JMneQ0YERFRURUlr3EImDSzaZMMczZsKKFv1CjpvWL4IyIiKlkcAibNZGXJMG5oqCwn0q4dsHmzHIuLK7gen2Hr1UvTsomIiMo8DgFTqZSRIZslHh7W77tLRETkqDgETGWer6/57cWIiIjIfjgETERERORgGACJiIiIHAwDIBEREZGDYQAkIiIicjAMgEREREQOhgGQiIiIyMEwABIRERE5GAZAIiIiIgfDAEhERETkYBgAiYiIiBwMAyARERGRg2EAJCIiInIwDIBEREREDoYBkIiIiMjBMAASERERORgGQCIiIiIHwwBIRERE5GAYAImIiIgcDAMgERERkYNhACQiIiJyMAyARERERA7G1ZZGSikAQGZmZokWQ0RERETFY8hphtx2PzYFwKysLABAUFDQA5RFRERERCUtKysL3t7e923jpGyIibm5ubh48SK8vLzg5ORktwKJiIiIyD6UUsjKykJgYCCcne9/lZ9NAZCIiIiIyg9OAiEiIiJyMAyARERERA6GAZCIiIjIwTAAEhERETkYBkAiIiIiB8MASERERORgGACJiIiIHMz/B6h5iV6QLBTlAAAAAElFTkSuQmCC", + "text/plain": [ + "
" + ] + }, + "execution_count": 5, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "from openfe.utils.atommapping_network_plotting import plot_atommapping_network\n", + "plot_atommapping_network(ligand_network)" + ] + }, + { + "cell_type": "markdown", + "id": "5f99678c", + "metadata": {}, + "source": [ + "We can also inspect the individual atom mappings:" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "c55cbcac", + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": 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", + "text/plain": [ + "" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "# get the first edge; it automatically displays in a Jupyter notebook\n", + "mapping = next(iter(ligand_network.edges))\n", + "mapping" + ] + }, + { + "cell_type": "markdown", + "id": "dd0c96d7", + "metadata": {}, + "source": [ + "To get the score for this mapping, we inspect its `annotations` attribute. Arbitrary annotations can be added when a mapping is created, although our network generator only includes the score." + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "id": "6b7492d7", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'score': 0.3296799539643607}" + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "# lower score is better\n", + "mapping.annotations" + ] + }, + { + "cell_type": "markdown", + "id": "838d9c49", + "metadata": {}, + "source": [ + "We can also use the py3dmol openfe interface to visualise our mappings in 3D" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "id": "e665b583", + "metadata": {}, + "outputs": [], + "source": [ + "from ipywidgets import interact, widgets\n", + "from openfe.utils.visualization_3D import view_mapping_3d\n", + "\n", + "edges = list(ligand_network.edges)\n", + "\n", + "def display_edge_3d(index):\n", + " view = view_mapping_3d(edges[index], spheres=True, show_atomIDs=True)\n", + " view.show()" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "id": "e9326f0c", + "metadata": {}, + "outputs": [ + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "9f4d7b210ff84b7fad4b9f2cf114a47c", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + "interactive(children=(IntSlider(value=0, description='index', max=17), Output()), _dom_classes=('widget-intera…" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "# traverse through all views\n", + "interact(display_edge_3d, index=widgets.IntSlider(min=0, max=len(edges)-1, step=1));" + ] + }, + { + "cell_type": "markdown", + "id": "30b276b6", + "metadata": {}, + "source": [ + "You can output the ligand network to the same `graphml` format as we saw in the CLI tutorial with the following:" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "id": "2263838f", + "metadata": {}, + "outputs": [], + "source": [ + "with open(\"ligand_network.graphml\", mode='w') as f:\n", + " f.write(ligand_network.to_graphml())" + ] + }, + { + "cell_type": "markdown", + "id": "056924a3", + "metadata": {}, + "source": [ + "## Creating a single `Transformation`\n", + "\n", + "The `LigandNetwork` only knows about the small molecules and the alchemical connections between them. It doesn't know anything about environment (e.g., solvent) or about the `Protocol` that will be used during the simulation.\n", + "\n", + "That information in included in a `Transformation`. Each of these transformations corresponds to a single leg of the simulation campaign, so for each edge in the `LigandNetwork`, we will create two `Transformation`s: one for the complex and one for solvent.\n", + "\n", + "In practice, this will be done for each edge of the `LigandNetwork` in a loop, but for illustrative purposes we'll dive into the details of creating a single transformation. In particular, we'll create the solvent leg for the pair of molecules we selecting for the mapping above." + ] + }, + { + "cell_type": "markdown", + "id": "d0cb1329", + "metadata": {}, + "source": [ + "### Creating `ChemicalSystem`s\n", + "\n", + "OpenFE describes complex molecular systems as being composed of `Component`s. For example, we have `SmallMoleculeComponent` for each small molecule being perturbed in the `LigandNetwork`. We will also create a `SolventComponent` to describe the solvent, a `ProteinComponent` for our EG5 complex simulations, and an extra `SmallMoleculeCompoinent` for the ATP cofactor bound to EG5.\n", + "\n", + "The `Component`s are joined in a `ChemicalSystem`, which describes all the particles in the simulation." + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "id": "9d2fbc22", + "metadata": {}, + "outputs": [], + "source": [ + "# defaults are water with NaCl at 0.15 M\n", + "solvent = openfe.SolventComponent()" + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "id": "3f1706ee", + "metadata": {}, + "outputs": [], + "source": [ + "# load in the EG5 protein\n", + "protein = openfe.ProteinComponent.from_pdb_file(\"./eg5_protein.pdb\")" + ] + }, + { + "cell_type": "code", + "execution_count": 13, + "id": "18e9cba5", + "metadata": {}, + "outputs": [], + "source": [ + "# load in the cofactor from eg5_cofactors.sdf, here we know that there is only one cofactor in the file\n", + "supp = Chem.SDMolSupplier(\"eg5_cofactor.sdf\", removeHs=False)\n", + "cofactor = [openfe.SmallMoleculeComponent.from_rdkit(mol) for mol in supp][0]" + ] + }, + { + "cell_type": "code", + "execution_count": 14, + "id": "710285ca", + "metadata": {}, + "outputs": [], + "source": [ + "systemA = openfe.ChemicalSystem({\n", + " 'ligand': mapping.componentA,\n", + " 'solvent': solvent,\n", + " 'protein': protein,\n", + " 'cofactor': cofactor,\n", + "})\n", + "systemB = openfe.ChemicalSystem({\n", + " 'ligand': mapping.componentB,\n", + " 'solvent': solvent,\n", + " 'protein': protein,\n", + " 'cofactor': cofactor,\n", + "})" + ] + }, + { + "cell_type": "markdown", + "id": "340d1a6e", + "metadata": {}, + "source": [ + "### Creating a `Protocol`\n", + "\n", + "The actual simulation is performed by a `Protocol`. We'll use an OpenMM-based hybrid topology relative free energy `Protocol`." + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "id": "3f394a0d", + "metadata": { + "scrolled": true + }, + "outputs": [], + "source": [ + "from openfe.protocols.openmm_rfe import RelativeHybridTopologyProtocol" + ] + }, + { + "cell_type": "markdown", + "id": "3bddfa3c", + "metadata": {}, + "source": [ + "The easiest way to customize protocol settings is to start with the default settings, and modify them. Many settings carry units with them." + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "id": "fb839094", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "'PME'" + ] + }, + "execution_count": 16, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "settings = RelativeHybridTopologyProtocol.default_settings()\n", + "settings.system_settings.nonbonded_method # display default value" + ] + }, + { + "cell_type": "markdown", + "id": "56658a3a", + "metadata": {}, + "source": [ + "We'll use the default settings for the protocol we'll use later, to match the behavior of the CLI." + ] + }, + { + "cell_type": "code", + "execution_count": 17, + "id": "7adf42d6", + "metadata": {}, + "outputs": [], + "source": [ + "default_settings = RelativeHybridTopologyProtocol.default_settings()\n", + "protocol = RelativeHybridTopologyProtocol(default_settings)" + ] + }, + { + "cell_type": "markdown", + "id": "318ff872", + "metadata": {}, + "source": [ + "### Creating the `Transformation`\n", + "\n", + "Once we have the mapping, the two `ChemicalSystem`s, and the `Protocol`, creating the `Transformation` is easy:" + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "id": "44ba94ca", + "metadata": {}, + "outputs": [], + "source": [ + "transformation = openfe.Transformation(\n", + " systemA,\n", + " systemB,\n", + " protocol,\n", + " mapping={'ligand': mapping},\n", + ")" + ] + }, + { + "cell_type": "markdown", + "id": "4283dfe4", + "metadata": {}, + "source": [ + "To summarize, this `Transformation` contains:\n", + "- chemical models of both sides of the alchemical transformation in `systemA` and `systemB`\n", + "- the correspondence of items in these two sides in `mapping` \n", + "- a description of the exact computational algorithm to use to perform the estimate in `protocol`" + ] + }, + { + "cell_type": "markdown", + "id": "1e29d1c8", + "metadata": {}, + "source": [ + "## Creating the `AlchemicalNetwork`\n", + "\n", + "The `AlchemicalNetwork` contains all the information needed to run the entire campaign. It consists of a `Transformation` for each leg of the campaign. We'll loop over all the mappings, and then loop over the legs. In that inner loop, we'll make each transformation." + ] + }, + { + "cell_type": "code", + "execution_count": 19, + "id": "66666a80", + "metadata": {}, + "outputs": [], + "source": [ + "transformations = []\n", + "for mapping in ligand_network.edges:\n", + " for leg in ['solvent', 'complex']:\n", + " # use the solvent and protein created above\n", + " sysA_dict = {'ligand': mapping.componentA,\n", + " 'solvent': solvent}\n", + " sysB_dict = {'ligand': mapping.componentB,\n", + " 'solvent': solvent}\n", + " \n", + " if leg == 'complex':\n", + " sysA_dict['protein'] = protein\n", + " sysB_dict['protein'] = protein\n", + " \n", + " # we don't have to name objects, but it can make things (like filenames) more convenient\n", + " sysA = openfe.ChemicalSystem(sysA_dict, name=f\"{mapping.componentA.name}_{leg}\")\n", + " sysB = openfe.ChemicalSystem(sysB_dict, name=f\"{mapping.componentB.name}_{leg}\")\n", + " \n", + " prefix = \"easy_rbfe_\" # prefix is only to exactly reproduce CLI\n", + " \n", + " transformation = openfe.Transformation(\n", + " stateA=sysA,\n", + " stateB=sysB,\n", + " mapping={'ligand': mapping},\n", + " protocol=protocol, # use protocol created above\n", + " name=f\"{prefix}{sysA.name}_{sysB.name}\"\n", + " )\n", + " transformations.append(transformation)\n", + "\n", + "network = openfe.AlchemicalNetwork(transformations)" + ] + }, + { + "cell_type": "markdown", + "id": "6c61fe36", + "metadata": {}, + "source": [ + "## Writing the `AlchemicalNetwork` to disk\n", + "\n", + "We'll write out each transformation to disk, so that they can be run independently using the `openfe quickrun` command:" + ] + }, + { + "cell_type": "code", + "execution_count": 20, + "id": "d6cebd9a", + "metadata": {}, + "outputs": [], + "source": [ + "import pathlib\n", + "# first we create the directory\n", + "transformation_dir = pathlib.Path(\"transformations\")\n", + "transformation_dir.mkdir(exist_ok=True)\n", + "\n", + "# then we write out each transformation\n", + "for transformation in network.edges:\n", + " transformation.dump(transformation_dir / f\"{transformation.name}.json\")" + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "id": "b96b57a9", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "easy_rbfe_lig_CHEMBL1082248_complex_lig_CHEMBL1082249_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1082248_complex_lig_CHEMBL1096002_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1082248_solvent_lig_CHEMBL1082249_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1082248_solvent_lig_CHEMBL1096002_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1083517_complex_lig_CHEMBL1086409_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1083517_solvent_lig_CHEMBL1086409_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1083836_complex_lig_CHEMBL1082248_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1083836_solvent_lig_CHEMBL1082248_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084143_complex_lig_CHEMBL1086410_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084143_solvent_lig_CHEMBL1086410_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_complex_lig_CHEMBL1084678_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_complex_lig_CHEMBL1085666_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_complex_lig_CHEMBL1096003_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_solvent_lig_CHEMBL1084678_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_solvent_lig_CHEMBL1085666_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084677_solvent_lig_CHEMBL1096003_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084935_complex_lig_CHEMBL1084935_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084935_complex_lig_CHEMBL1086410_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1084935_solvent_lig_CHEMBL1084935_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1084935_solvent_lig_CHEMBL1086410_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_complex_lig_CHEMBL1077204_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_complex_lig_CHEMBL1084676_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_complex_lig_CHEMBL1086409_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_solvent_lig_CHEMBL1077204_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_solvent_lig_CHEMBL1084676_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1085666_solvent_lig_CHEMBL1086409_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1085692_complex_lig_CHEMBL1082248_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1085692_solvent_lig_CHEMBL1082248_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1086409_complex_lig_CHEMBL1082248_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1086409_complex_lig_CHEMBL1093087_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1086409_solvent_lig_CHEMBL1082248_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1086409_solvent_lig_CHEMBL1093087_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1086410_complex_lig_CHEMBL1077227_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1086410_complex_lig_CHEMBL1082248_complex.json\r\n", + "easy_rbfe_lig_CHEMBL1086410_solvent_lig_CHEMBL1077227_solvent.json\r\n", + "easy_rbfe_lig_CHEMBL1086410_solvent_lig_CHEMBL1082248_solvent.json\r\n" + ] + } + ], + "source": [ + "!ls transformations/" + ] + }, + { + "cell_type": "markdown", + "id": "c30e8ae2", + "metadata": {}, + "source": [ + "Each of these individual `.json` files contains a `Transformation`, which contains all the information to run the calculation. These could be farmed out as individual jobs on a HPC cluster. These files are identical to what were created in setup stage of the CLI tutorial; for details on running them, follow from the section on running simulations in the CLI tutorial" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.16" + } + }, + "nbformat": 4, + "nbformat_minor": 5 +}