diff --git a/cvdo.obo b/cvdo.obo deleted file mode 100644 index c2df0ae..0000000 --- a/cvdo.obo +++ /dev/null @@ -1,2439 +0,0 @@ -format-version: 1.2 -data-version: 2024-05-17 -remark: CVDO is an ontology of cardiovascular diseases structured on OBO foundry’s principle and based on BFO. CVDO reorganizes and completes DOID cardiovascular diseases following OGMS tripartite model of disease, and builds its taxonomy of diseases largely by automatic reasoning. -import: http://purl.obolibrary.org/obo/bfo/2014-05-03/bfo.owl -import: http://purl.obolibrary.org/obo/CVDO/releases/2013-04-04/imports/doid_import.owl -import: http://purl.obolibrary.org/obo/CVDO/releases/2024-05-17/imports/fma_import.owl -import: http://purl.obolibrary.org/obo/CVDO/releases/2024-05-17/imports/ogms_import.owl -ontology: cvdo -property_value: http://purl.org/dc/elements/1.1/creator "Adrien Barton" xsd:string -property_value: http://purl.org/dc/elements/1.1/creator "Arnaud Rosier" xsd:string -property_value: http://purl.org/dc/elements/1.1/creator "Jean-François Ethier" xsd:string -property_value: http://purl.org/dc/elements/1.1/creator "Paul Fabry" xsd:string -property_value: http://purl.org/dc/terms/license http://creativecommons.org/licenses/by/4.0/ xsd:string -property_value: http://purl.org/dc/terms/title "Cardio Vascular Disease Ontology" xsd:string -property_value: owl:versionInfo "2024-05-17" xsd:string -owl-axioms: Prefix(owl:=)\nPrefix(rdf:=)\nPrefix(xml:=)\nPrefix(xsd:=)\nPrefix(rdfs:=)\n\n\nOntology(\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(AnnotationProperty())\nDeclaration(AnnotationProperty())\nDeclaration(AnnotationProperty())\nDeclaration(AnnotationProperty())\n############################\n# Annotation Properties\n############################\n\n# Annotation Property: (CVDO definition)\n\nSubAnnotationPropertyOf( )\n\n# Annotation Property: (CVDO editor note)\n\nSubAnnotationPropertyOf( )\n\n\n\n############################\n# Classes\n############################\n\n# Class: (atrioventricular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (first degree atrioventricular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (Mobitz I second degree atrioventricular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (third degree atrioventricular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (sinoatrial block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (Mobitz I second degree sinoatrial block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (Mobitz II second degree sinoatrial block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (first degree sinoatrial block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (third degree sinoatrial block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (heart block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (left posterior fascicular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (infra-hisian block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (left bundle branch block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (cardiac arrhythmia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (atrial fibrillation (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\nDisjointUnion( )\n\n# Class: (atrial flutter (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (common atrial flutter (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (bradycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (premature atrial contraction (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (wandering pacemaker)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (tricuspid valve disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (heart valve stenosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (heart valve insufficiency)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (ischemic disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (pericardium disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (supraventricular tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (left atrial flutter (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (right atrial flutter (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (junctional tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (atrioventricular nodal reentrant tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (inflammation process in an iliac vein)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (Barlow's syndrome)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (tachycardia-bradycardia syndrome)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (inappropriate sinus tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (sinus bradycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (sinoatrial arrest (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (atrioventricular reciprocating tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (ventricular tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (ventricular flutter (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (torsades de pointes (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (monomorphic ventricular tachycardia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (ventricular fibrillation (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (premature contraction (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (premature junctional contraction (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (premature ventricular contraction (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (coronary heart disease with stable angina)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (angina pectoris)\n\nDisjointUnion( )\n\n# Class: (unstable angina pectoris)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (ventricular preexcitation (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (pulmonary valve prolapse)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (ventricular tachyarrhythmia (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (inflammatory disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (endocardium disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (ischemic cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (disease of material anatomical entity)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (valvular cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (inflammatory dilated cardiomyopathy)\n\n\n# Class: (hypertensive cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (congenital heart disease)\n\n\n# Class: (heart ventricle disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (left ventricle disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (right ventricle disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (myocardium disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (arrhythmogenic right ventricular dysplasia)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (Brugada syndrome)\n\nSubClassOf( ObjectAllValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (cardiomyopathy (1995 definition))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\nDisjointUnion( ObjectIntersectionOf( ) ObjectIntersectionOf( ) ObjectIntersectionOf( ) ObjectIntersectionOf( ))\n\n# Class: (infective endocarditis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (non-bacterial thrombotic endocarditis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (venous insufficiency)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (aortic atherosclerosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))))\n\n# Class: (left anterior fascicular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (heart conduction disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (endocarditis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (anomalous atrioventricular excitation (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (hypertension)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (Mobitz II second degree atrioventricular block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (heart disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (hemopericardium)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (cardiac tamponade)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (mitral valve insufficiency)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (hypertensive heart disease)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (retinal vasculitis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (pericardial effusion)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (coronary artery vasospasm)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (hypertrophic cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (femoral vein thrombophlebitis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (chronic pulmonary heart disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (cardiovascular system disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (endocardial fibroelastosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (dilated cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (right bundle branch block (disease))\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (sick sinus syndrome)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))))\n\n# Class: (pulmonary valve insufficiency)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (aortic valve stenosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (mitral valve stenosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (vascular disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (pericarditis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (chronic rheumatic pericarditis)\n\nSubClassOf( ObjectIntersectionOf( ObjectSomeValuesFrom( )))\n\n# Class: (supravalvular aortic stenosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (atherosclerosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (arteriosclerosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (arterial occlusive disease)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (coronary arteriosclerosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (coronary heart disease)\n\n\n# Class: (ischemic heart disease)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (Wolff-Parkinson-White syndrome)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (thrombophlebitis)\n\nSubClassOf( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (Loeffler endocarditis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (restrictive cardiomyopathy)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))))\n\n# Class: (tricuspid valve stenosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (heart valve disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (tricuspid valve insufficiency)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (intracranial embolism)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (aortitis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (aortic disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (aortic valve prolapse)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (central nervous system vasculitis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (tricuspid valve prolapse)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (aortic valve insufficiency)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (pulmonary valve disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (subvalvular aortic stenosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (myocardial infarction)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (congestive heart failure)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nDisjointUnion( )\n\n# Class: (mitral valve disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (aortic valve disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (pulmonary valve stenosis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (myocarditis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (acute pulmonary heart disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (cor pulmonale)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( ))))\nDisjointUnion( )\n\n# Class: (acute cor pulmonale)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (phlebitis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (vasculitis)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))\n\n# Class: (vein disease)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( ))))\n\n# Class: (subvalvular pulmonary stenosis)\n\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\nSubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))\n\n# Class: (mitral valve prolapse)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n# Class: (heart valve prolapse)\n\nEquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))\n\n\nDisjointClasses( )\nDisjointClasses( )\nDisjointClasses( )\n) - -[Term] -id: CVDO:0000010 -name: bacterial endocarditis -is_a: DOID:0060000 ! infective endocarditis -property_value: CVDO:0000419 "An endocarditis caused by bacterial infection." xsd:string - -[Term] -id: CVDO:0000011 -name: viral endocarditis -is_a: DOID:0060000 ! infective endocarditis -property_value: CVDO:0000419 "An endocarditis caused by viral infection." xsd:string - -[Term] -id: CVDO:0000012 -name: fungal endocarditis -is_a: DOID:0060000 ! infective endocarditis -property_value: CVDO:0000419 "An endocarditis caused by fungal infection." xsd:string - -[Term] -id: CVDO:0000015 -name: heart disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7088 ! located in at all times Heart -property_value: CVDO:0000419 "A disorder located in the heart." xsd:string - -[Term] -id: CVDO:0000016 -name: vascular disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:3710 ! located in at all times Vascular tree -property_value: CVDO:0000419 "A disorder always located in a blood vessel." xsd:string - -[Term] -id: CVDO:0000020 -name: endocardium disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7280 ! located in at all times Endocardium -property_value: CVDO:0000419 "A disorder always located in the endocardium." xsd:string - -[Term] -id: CVDO:0000023 -name: pericardium disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:9869 ! located in at all times Pericardium -property_value: CVDO:0000419 "A disorder always located in the pericardium." xsd:string -property_value: CVDO:0000533 "Since the pericardium is not a part of the heart according to FMA, pericardium disorder is not classified as a heart disorder." xsd:string - -[Term] -id: CVDO:0000033 -name: infectious pericarditis -is_a: DOID:1787 ! pericarditis -property_value: CVDO:0000419 "A pericarditis caused by an infection." xsd:string - -[Term] -id: CVDO:0000034 -name: bacterial pericarditis -is_a: CVDO:0000033 ! infectious pericarditis -property_value: CVDO:0000419 "A pericarditis caused by a bacterial infection." xsd:string - -[Term] -id: CVDO:0000035 -name: viral pericarditis -is_a: CVDO:0000033 ! infectious pericarditis -property_value: CVDO:0000419 "A pericarditis caused by a viral infection." xsd:string - -[Term] -id: CVDO:0000036 -name: fungal pericarditis -is_a: CVDO:0000033 ! infectious pericarditis -property_value: CVDO:0000419 "A pericarditis caused by a fungal infection." xsd:string - -[Term] -id: CVDO:0000037 -name: protozoal pericarditis -is_a: CVDO:0000033 ! infectious pericarditis - -[Term] -id: CVDO:0000039 -name: heart pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -property_value: CVDO:0000419 "A pathological process involving or occuring in the heart." xsd:string - -[Term] -id: CVDO:0000040 -name: pericardium pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:9869 ! occurs in Pericardium -property_value: CVDO:0000419 "A pathological process involving or occuring in the pericardium." xsd:string - -[Term] -id: CVDO:0000041 -name: acute pericarditis -intersection_of: DOID:1787 ! pericarditis -intersection_of: BFO:0000054 OGMS:0000094 ! realized in acute disease course -property_value: CVDO:0000419 "A pericarditis that has an acute disease course." xsd:string - -[Term] -id: CVDO:0000042 -name: chronic pericarditis -intersection_of: DOID:1787 ! pericarditis -intersection_of: BFO:0000054 OGMS:0000064 ! realized in chronic disease course -property_value: CVDO:0000419 "A pericarditis that has a chronic disease course." xsd:string - -[Term] -id: CVDO:0000043 -name: atrioventricular block (disease) -relationship: BFO:0000113 CVDO:0000048 ! has material basis at all times impaired atrioventricular node - -[Term] -id: CVDO:0000044 -name: first degree atrioventricular block (disease) - -[Term] -id: CVDO:0000045 -name: Mobitz I second degree atrioventricular block (disease) - -[Term] -id: CVDO:0000046 -name: third degree atrioventricular block (disease) -synonym: "complete heart block" EXACT [] - -[Term] -id: CVDO:0000047 -name: heart conduction disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:83378 ! located in at all times Conducting tissue of heart -property_value: CVDO:0000419 "A disorder always loacted in the conducting tissue of the heart." xsd:string - -[Term] -id: CVDO:0000048 -name: impaired atrioventricular node -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000051 -name: impaired right branch of atrioventricular bundle -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000052 -name: bundle of Kent -is_a: CVDO:0000463 ! atrioventricular accessory bundle - -[Term] -id: CVDO:0000061 -name: sinoatrial block (disease) -relationship: BFO:0000113 CVDO:0000066 ! has material basis at all times impaired sinoatrial node - -[Term] -id: CVDO:0000062 -name: Mobitz I second degree sinoatrial block (disease) -synonym: "Wenckebach block" EXACT [] - -[Term] -id: CVDO:0000063 -name: Mobitz II second degree sinoatrial block (disease) -synonym: "sinus exit block" EXACT [] - -[Term] -id: CVDO:0000064 -name: first degree sinoatrial block (disease) - -[Term] -id: CVDO:0000065 -name: third degree sinoatrial block (disease) - -[Term] -id: CVDO:0000066 -name: impaired sinoatrial node -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000072 -name: heart block (disease) - -[Term] -id: CVDO:0000077 -name: impaired posterior division of left branch of atrioventricular bundle -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000080 -name: left posterior fascicular block (disease) -relationship: BFO:0000113 CVDO:0000077 ! has material basis at all times impaired posterior division of left branch of atrioventricular bundle - -[Term] -id: CVDO:0000081 -name: infra-hisian block (disease) - -[Term] -id: CVDO:0000082 -name: left bundle branch block (disease) - -[Term] -id: CVDO:0000088 -name: cardiac arrhythmia (disease) -property_value: CVDO:0000419 "A heart conduction disease characterized by cardiac arrhythmia processes." xsd:string -property_value: CVDO:0000533 "Usual medical language does not differentiate the disease and the corresponding pathological process for the different kinds of cardiac arrhythmias. CVDO distinguishes them explicitly with the suffix '(disease)' or '(process)'." xsd:string - -[Term] -id: CVDO:0000092 -name: atrial fibrillation (disease) - -[Term] -id: CVDO:0000093 -name: atrial fibrillation (process) -is_a: CVDO:0000111 ! supraventricular tachycardia (process) - -[Term] -id: CVDO:0000094 -name: atrial flutter (disease) - -[Term] -id: CVDO:0000097 -name: common atrial flutter (disease) -synonym: "cavotricuspid isthmus dependant macroreentry tachycardia" EXACT [] -synonym: "type I atrial flutter" EXACT [] - -[Term] -id: CVDO:0000110 -name: cardiac atrium fibrosis -is_a: CVDO:0000273 ! cardiac atrium pathological process -relationship: BFO:0000066 FMA:7099 ! occurs in Cardiac atrium -property_value: CVDO:0000419 "A pathological process of fibrosis of the cardiac atrium." xsd:string - -[Term] -id: CVDO:0000111 -name: supraventricular tachycardia (process) -is_a: CVDO:0000445 ! tachycardia (process) - -[Term] -id: CVDO:0000139 -name: bradycardia (disease) - -[Term] -id: CVDO:0000140 -name: bradycardia (process) -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000143 -name: premature atrial contraction (disease) - -[Term] -id: CVDO:0000144 -name: left anterior fascicle -is_a: FMA:6266 ! Subdivision of conducting system of heart - -[Term] -id: CVDO:0000148 -name: heart valve disorder -def: "A disorder always located in a heart valve." [] -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7110 ! located in at all times Cardiac valve - -[Term] -id: CVDO:0000153 -name: wandering pacemaker -is_a: DOID:10273 ! heart conduction disease - -[Term] -id: CVDO:0000154 -name: tricuspid valve disease -property_value: CVDO:0000419 "A disease affecting the tricuspid valve of the heart." xsd:string - -[Term] -id: CVDO:0000156 -name: myxomatous degenerated structure in a mitral valve leaflet -def: "A degenerated structure in a mitral valve leaflet due to myxomatous proliferation." [] -is_a: CVDO:0000420 ! degenerated structure in a heart valve leaflet -relationship: BFO:0000082 FMA:7235 ! located in at all times Mitral valve - -[Term] -id: CVDO:0000159 -name: heart pathological process involving a heart valve -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -intersection_of: BFO:0000167 FMA:7110 ! has participant at all times Cardiac valve -property_value: CVDO:0000419 "A heart pathological process that has a heart valve as a participant." xsd:string -property_value: CVDO:0000533 "This class should not be confused with 'heart valve pathological process', which are pathological processes occurring in a heart valve, rather than pathological process having as participant a heart valve." xsd:string - -[Term] -id: CVDO:0000160 -name: mitral valve leaflet displacement into the left atrium during left ventricular systole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000524 ! part of occurrent left ventricular systole -intersection_of: BFO:0000167 FMA:7235 ! has participant at all times Mitral valve - -[Term] -id: CVDO:0000162 -name: tricuspid valve leaflet displacement into the right atrium during right ventricular systole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000525 ! part of occurrent right ventricular systole -intersection_of: BFO:0000167 FMA:7234 ! has participant at all times Tricuspid valve - -[Term] -id: CVDO:0000163 -name: aortic valve leaflet displacement into the left ventricle during left ventricular diastole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000522 ! part of occurrent left ventricular diastole -intersection_of: BFO:0000167 FMA:7236 ! has participant at all times Aortic valve - -[Term] -id: CVDO:0000164 -name: heart valve leaflet displacement into a cardiac chamber during ventricular systole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000518 ! part of occurrent ventricular systole - -[Term] -id: CVDO:0000166 -name: mitral valve improper close during left ventricular systole -intersection_of: CVDO:0000210 ! heart valve improper close -intersection_of: BFO:0000132 CVDO:0000524 ! part of occurrent left ventricular systole -intersection_of: BFO:0000167 FMA:7235 ! has participant at all times Mitral valve - -[Term] -id: CVDO:0000168 -name: retrograd blood flow through mitral valve during left ventricular systole -is_a: CVDO:0000182 ! retrograd blood flow through a heart valve - -[Term] -id: CVDO:0000169 -name: retrograd blood flow through pulmonary valve during right ventricular diastole -is_a: CVDO:0000182 ! retrograd blood flow through a heart valve - -[Term] -id: CVDO:0000170 -name: pulmonary valve improper close during right ventricular diastole -intersection_of: CVDO:0000210 ! heart valve improper close -intersection_of: BFO:0000132 CVDO:0000523 ! part of occurrent right ventricular diastole -intersection_of: BFO:0000167 FMA:7246 ! has participant at all times Pulmonary valve - -[Term] -id: CVDO:0000171 -name: tricuspid valve improper close during right ventricular systole -intersection_of: CVDO:0000210 ! heart valve improper close -intersection_of: BFO:0000132 CVDO:0000525 ! part of occurrent right ventricular systole -intersection_of: BFO:0000167 FMA:7234 ! has participant at all times Tricuspid valve - -[Term] -id: CVDO:0000172 -name: aortic valve improper close during left ventricular diastole -intersection_of: CVDO:0000210 ! heart valve improper close -intersection_of: BFO:0000132 CVDO:0000522 ! part of occurrent left ventricular diastole -intersection_of: BFO:0000167 FMA:7236 ! has participant at all times Aortic valve - -[Term] -id: CVDO:0000173 -name: retrograd blood flow through tricuspid valve during right ventricular systole -is_a: CVDO:0000182 ! retrograd blood flow through a heart valve - -[Term] -id: CVDO:0000175 -name: retrograd blood flow through aortic valve during left ventricular diastole -is_a: CVDO:0000182 ! retrograd blood flow through a heart valve - -[Term] -id: CVDO:0000181 -name: disturbed anterograd blood flow through mitral valve during left ventricular diastole -is_a: CVDO:0000183 ! disturbed anterograd blood flow through a heart valve - -[Term] -id: CVDO:0000182 -name: retrograd blood flow through a heart valve -is_a: CVDO:0000279 ! cardiac blood circulation pathological process - -[Term] -id: CVDO:0000183 -name: disturbed anterograd blood flow through a heart valve -is_a: CVDO:0000279 ! cardiac blood circulation pathological process - -[Term] -id: CVDO:0000184 -name: disturbed anterograd blood flow through tricuspid valve during right ventricular diastole -is_a: CVDO:0000183 ! disturbed anterograd blood flow through a heart valve - -[Term] -id: CVDO:0000186 -name: disturbed anterograd blood flow through pulmonary valve during right ventricular systole -is_a: CVDO:0000183 ! disturbed anterograd blood flow through a heart valve - -[Term] -id: CVDO:0000187 -name: disturbed anterograd blood flow through aortic valve during left ventricular systole -is_a: CVDO:0000183 ! disturbed anterograd blood flow through a heart valve - -[Term] -id: CVDO:0000189 -name: heart valve stenosis -property_value: CVDO:0000419 "A disease in which some disorder of a heart valve prevents it from opening properly, occasioning disturbance in the anterograd blood flow through the valve." xsd:string - -[Term] -id: CVDO:0000191 -name: impaired cardiac output -is_a: CVDO:0000279 ! cardiac blood circulation pathological process - -[Term] -id: CVDO:0000193 -name: pressure -is_a: BFO:0000019 ! quality - -[Term] -id: CVDO:0000194 -name: blood pressure -is_a: CVDO:0000193 ! pressure - -[Term] -id: CVDO:0000196 -name: highly pressured arterial blood flow -is_a: CVDO:0000280 ! vascular blood circulation pathological process -property_value: CVDO:0000419 "A pathological process of highly pressured aerterial blood flow." xsd:string - -[Term] -id: CVDO:0000209 -name: heart valve insufficiency -property_value: CVDO:0000419 "A disease in which an abnormal structure in a heart valve prevents it to close propertly, occasioning a retrograd blood flow through the valve." xsd:string - -[Term] -id: CVDO:0000210 -name: heart valve improper close -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:7088 ! occurs in Heart -relationship: BFO:0000167 FMA:7110 ! has participant at all times Cardiac valve -property_value: CVDO:0000419 "A pathological process of a heart valve closing improperly." xsd:string - -[Term] -id: CVDO:0000214 -name: vein disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:14284 ! located in at all times Venous tree organ -property_value: CVDO:0000419 "A disorder always located in a vein." xsd:string - -[Term] -id: CVDO:0000216 -name: vascular pathological process -is_a: OGMS:0000061 ! pathological bodily process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:3710 ! occurs in Vascular tree -property_value: CVDO:0000419 "A pathological process involving or occuring in a blood vessel." xsd:string - -[Term] -id: CVDO:0000217 -name: thrombosis -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -property_value: CVDO:0000419 "A pathological process of formation of a blood clot inside a blood vessel, obstructing the flow of blood." xsd:string - -[Term] -id: CVDO:0000220 -name: deep vein thrombosis -is_a: CVDO:0000217 ! thrombosis -property_value: CVDO:0000419 "A thrombosis occurring in a deep vein." xsd:string - -[Term] -id: CVDO:0000223 -name: artery hardening -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:45840 ! occurs in Arterial tree organ -property_value: CVDO:0000419 "A pathological process of an artery hardening." xsd:string - -[Term] -id: CVDO:0000224 -name: atheromous plaque formation in artery -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:50720 ! occurs in Artery -property_value: CVDO:0000419 "A pathological process of formation of atheromous plaques in an artery." xsd:string - -[Term] -id: CVDO:0000225 -name: embolism -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -relationship: BFO:0000167 CVDO:0000545 ! has participant at all times embolus -property_value: CVDO:0000419 "A pathological process of lodging of an embolus in a blood vessel." xsd:string - -[Term] -id: CVDO:0000226 -name: aneurysm (disorder) -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:3710 ! located in at all times Vascular tree -property_value: CVDO:0000419 "A disorder of localized, blood-filled balloon-like bulge in the wall of a blood vessel." xsd:string - -[Term] -id: CVDO:0000231 -name: ischemic disease - -[Term] -id: CVDO:0000234 -name: compression disease -is_a: DOID:178 ! vascular disease - -[Term] -id: CVDO:0000238 -name: permanent atrial fibrillation -is_a: CVDO:0000092 ! atrial fibrillation (disease) -relationship: BFO:0000054 OGMS:0000064 ! realized in chronic disease course -property_value: CVDO:0000419 "An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does not terminate by cardioversion." xsd:string - -[Term] -id: CVDO:0000239 -name: right ventricular myocardium dilatation -intersection_of: CVDO:0000330 ! ventricular myocardium dilatation -intersection_of: BFO:0000066 FMA:9535 ! occurs in Myocardium of right ventricle -property_value: CVDO:0000419 "A pathological process of dilatation of the myocardium of a right cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000240 -name: aneurysm rupture -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -relationship: BFO:0000167 CVDO:0000226 ! has participant at all times aneurysm (disorder) -property_value: CVDO:0000419 "A pathological process of an aneurysm rupturing." xsd:string - -[Term] -id: CVDO:0000248 -name: myocardium disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:9462 ! located in at all times Myocardium -property_value: CVDO:0000419 "A disorder always located in the mycoardium." xsd:string - -[Term] -id: CVDO:0000254 -name: Tako Tsubo cardiomyopathy -is_a: DOID:0050700 ! cardiomyopathy (1995 definition) -relationship: BFO:0000054 OGMS:0000066 ! realized in transient disease course -property_value: CVDO:0000419 "A cardiomyopathy whose etiological process includes a stressful or emotional situation, characterized by transient ventricular apical wall motion abnormalities (ballooning)." xsd:string -property_value: CVDO:0000533 "Tako-Tsubo cardiomyopathy is not a dilated cardiomyopathy in Elliott et al.'s (2008) classification." xsd:string - -[Term] -id: CVDO:0000255 -name: left ventricular noncompaction -synonym: "noncompaction cardiomyopathy" EXACT [] -is_a: CVDO:0000569 ! cardiomyopathy (2008 definition) -property_value: CVDO:0000419 "\"A cardiomyopathy characterized by prominent left ventricular trabeculae and deep inter-trabecular recesses. The myocardial wall is often thickened with a thin, compacted epicardial layer and a thickened endocardial layer.\" (Elliott et al., 2008)" xsd:string - -[Term] -id: CVDO:0000256 -name: genetic hypertrophic cardiomyopathy -intersection_of: DOID:11984 ! hypertrophic cardiomyopathy -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A hypertrophic cardiomyopathy that has a genetic origin." xsd:string - -[Term] -id: CVDO:0000262 -name: pericardium disease -property_value: CVDO:0000419 "A disease affecting the pericardium." xsd:string -property_value: CVDO:0000533 "Since pericardium is not a part of heart according to FMA, pericardium disease is not classified as a heart disease." xsd:string - -[Term] -id: CVDO:0000267 -name: vascular disease - unclassified by CVDO -is_a: DOID:178 ! vascular disease -property_value: CVDO:0000533 "This is a dummy class not intended to be included in CVDO's final version, used to store temporarily DOID's vascular diseases that may be reclassified in the future." xsd:string - -[Term] -id: CVDO:0000273 -name: cardiac atrium pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7099 ! occurs in Cardiac atrium -property_value: CVDO:0000419 "A pathological process occuring in a cardiac atrium." xsd:string - -[Term] -id: CVDO:0000274 -name: cardiac ventricle pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7100 ! occurs in Cardiac ventricle -property_value: CVDO:0000419 "A pathological process occurring in a cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000275 -name: thromboembolism -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -relationship: BFO:0000117 CVDO:0000217 ! has occurrent part thrombosis -relationship: BFO:0000117 CVDO:0000225 ! has occurrent part embolism -property_value: CVDO:0000419 "A pathological process constituted by a thrombosis (creating a blood clot) and a subsequent embolism (involving the blood clot as the embolus)." xsd:string - -[Term] -id: CVDO:0000276 -name: infarction -is_a: OGMS:0000061 ! pathological bodily process -property_value: CVDO:0000419 "A necrosis of a tissue caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply." xsd:string - -[Term] -id: CVDO:0000277 -name: pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000523 ! part of occurrent right ventricular diastole -intersection_of: BFO:0000167 FMA:7246 ! has participant at all times Pulmonary valve - -[Term] -id: CVDO:0000279 -name: cardiac blood circulation pathological process -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:7088 ! occurs in Heart -property_value: CVDO:0000419 "A pathological process involving the blood circuation in the heart." xsd:string - -[Term] -id: CVDO:0000280 -name: vascular blood circulation pathological process -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -property_value: CVDO:0000419 "A pathological process involving the blood circulation in a blood vessel." xsd:string - -[Term] -id: CVDO:0000281 -name: part of atrial myocardium with impaired conduction -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:9462 ! located in at all times Myocardium - -[Term] -id: CVDO:0000284 -name: diabetic microangiopathy -is_a: DOID:11713 ! diabetic angiopathy - -[Term] -id: CVDO:0000285 -name: diabetic macroangiopathy -is_a: DOID:11713 ! diabetic angiopathy - -[Term] -id: CVDO:0000288 -name: atheromous plaque formation in coronary artery -intersection_of: CVDO:0000224 ! atheromous plaque formation in artery -intersection_of: BFO:0000066 FMA:49893 ! occurs in Coronary artery -property_value: CVDO:0000419 "A pathological process consisting in the formation of atheromous plaques in a coronary artery. It may lead to a coronary stenosis." xsd:string - -[Term] -id: CVDO:0000293 -name: atherosclerotic coronary heart disease -intersection_of: DOID:3393 ! coronary heart disease -intersection_of: BFO:0000113 DOID:4248 ! has material basis at all times coronary stenosis -property_value: CVDO:0000419 "A coronary heart disease due to a coronary stenosis." xsd:string - -[Term] -id: CVDO:0000294 -name: left ventricular myocardium dilatation -intersection_of: CVDO:0000330 ! ventricular myocardium dilatation -intersection_of: BFO:0000066 FMA:9558 ! occurs in Myocardium of left ventricle -property_value: CVDO:0000419 "A pathological process of dilatation of the myocardium of a left cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000296 -name: supraventricular tachycardia (disease) - -[Term] -id: CVDO:0000298 -name: left atrial flutter (disease) -disjoint_from: CVDO:0000299 ! right atrial flutter (disease) - -[Term] -id: CVDO:0000299 -name: right atrial flutter (disease) - -[Term] -id: CVDO:0000301 -name: junctional tachycardia (disease) - -[Term] -id: CVDO:0000304 -name: atrioventricular nodal reentrant tachycardia (disease) - -[Term] -id: CVDO:0000306 -name: atrial flutter (process) -is_a: CVDO:0000111 ! supraventricular tachycardia (process) - -[Term] -id: CVDO:0000307 -name: ventricular fibrillation (process) -is_a: CVDO:0000489 ! ventricular tachyarrhythmia (process) - -[Term] -id: CVDO:0000308 -name: junctional tachycardia (process) -is_a: CVDO:0000111 ! supraventricular tachycardia (process) - -[Term] -id: CVDO:0000309 -name: premature atrial contraction (process) -is_a: CVDO:0000439 ! premature contraction (process) - -[Term] -id: CVDO:0000310 -name: cardiac arrhythmia (process) -is_a: CVDO:0000534 ! heart conduction pathological process -property_value: CVDO:0000419 "A pathological process involving the electrical activity of the heart." xsd:string - -[Term] -id: CVDO:0000311 -name: heart block (process) -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000312 -name: atrioventricular block (process) -is_a: CVDO:0000311 ! heart block (process) - -[Term] -id: CVDO:0000313 -name: infra-hisian block (process) -is_a: CVDO:0000311 ! heart block (process) - -[Term] -id: CVDO:0000314 -name: sinoatrial block (process) -is_a: CVDO:0000311 ! heart block (process) - -[Term] -id: CVDO:0000315 -name: Mobitz I second degree atrioventricular block (process) -is_a: CVDO:0000312 ! atrioventricular block (process) - -[Term] -id: CVDO:0000316 -name: Mobitz II second degree atrioventricular block (process) -is_a: CVDO:0000312 ! atrioventricular block (process) - -[Term] -id: CVDO:0000317 -name: first degree atrioventricular block (process) -is_a: CVDO:0000312 ! atrioventricular block (process) - -[Term] -id: CVDO:0000318 -name: third degree atrioventricular block (process) -is_a: CVDO:0000312 ! atrioventricular block (process) - -[Term] -id: CVDO:0000319 -name: left anterior fascicular block (process) -is_a: CVDO:0000313 ! infra-hisian block (process) - -[Term] -id: CVDO:0000320 -name: left bundle branch block (process) -is_a: CVDO:0000313 ! infra-hisian block (process) - -[Term] -id: CVDO:0000321 -name: left posterior fascicular block (process) -is_a: CVDO:0000313 ! infra-hisian block (process) - -[Term] -id: CVDO:0000322 -name: right bundle branch block (process) -is_a: CVDO:0000313 ! infra-hisian block (process) - -[Term] -id: CVDO:0000323 -name: Mobitz I second degree sinoatrial block (process) -is_a: CVDO:0000314 ! sinoatrial block (process) - -[Term] -id: CVDO:0000324 -name: Mobitz II second degree sinoatrial block (process) -is_a: CVDO:0000314 ! sinoatrial block (process) - -[Term] -id: CVDO:0000325 -name: first degree sinoatrial block (process) -is_a: CVDO:0000314 ! sinoatrial block (process) - -[Term] -id: CVDO:0000326 -name: third degree sinoatrial block (process) -is_a: CVDO:0000314 ! sinoatrial block (process) - -[Term] -id: CVDO:0000327 -name: coronary artery disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:49893 ! located in at all times Coronary artery -property_value: CVDO:0000419 "A disorder always located in a coronary artery." xsd:string - -[Term] -id: CVDO:0000330 -name: ventricular myocardium dilatation -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:12151 ! occurs in Myocardium of ventricle -property_value: CVDO:0000419 "A pathological process of dilatation of the myocardium of a cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000331 -name: ventricular myocardium hypertrophy -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:12151 ! occurs in Myocardium of ventricle -property_value: CVDO:0000419 "A pathological process of hypertrophy of the myocardium of a cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000332 -name: left ventricular myocardium hypertrophy -intersection_of: CVDO:0000331 ! ventricular myocardium hypertrophy -intersection_of: BFO:0000066 FMA:9558 ! occurs in Myocardium of left ventricle -property_value: CVDO:0000419 "A pathological process of hypertrophy of the myocardium of a left cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000333 -name: right ventricular myocardium hypertrophy -intersection_of: CVDO:0000331 ! ventricular myocardium hypertrophy -intersection_of: BFO:0000066 FMA:9535 ! occurs in Myocardium of right ventricle -property_value: CVDO:0000419 "A pathological process of hypertrophy of the myocardium of a right cardiac ventricle." xsd:string - -[Term] -id: CVDO:0000403 -name: pathological inflammation process -is_a: OGMS:0000061 ! pathological bodily process -property_value: CVDO:0000419 "A pathological process of an organ or part of organ getting inflamed." xsd:string - -[Term] -id: CVDO:0000404 -name: inflammation process in a myocardium -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:9462 ! occurs in Myocardium -property_value: CVDO:0000419 "An inflammation process occurring in the myocardium." xsd:string - -[Term] -id: CVDO:0000405 -name: inflammation process in an endocardium -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:7280 ! occurs in Endocardium -property_value: CVDO:0000419 "An inflammation process occurring in the endocardium." xsd:string - -[Term] -id: CVDO:0000406 -name: inflammation process in a pericardium -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:9869 ! occurs in Pericardium -property_value: CVDO:0000419 "An inflammation process occurring in the pericardium." xsd:string - -[Term] -id: CVDO:0000407 -name: inflammation process in aorta -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:3734 ! occurs in Aorta -property_value: CVDO:0000419 "An inflammation process occurring in the aorta." xsd:string - -[Term] -id: CVDO:0000408 -name: inflammation process in a blood vessel -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:3710 ! occurs in Vascular tree -property_value: CVDO:0000419 "An inflammation process in a blood vessel." xsd:string - -[Term] -id: CVDO:0000409 -name: inflammation process in a femoral vein -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:21185 ! occurs in Femoral vein -property_value: CVDO:0000419 "An inflammation process occurring in the femoral vein." xsd:string - -[Term] -id: CVDO:0000410 -name: inflammation process in an iliac vein -property_value: CVDO:0000419 "An inflammation process occurring in an iliac vein." xsd:string - -[Term] -id: CVDO:0000411 -name: inflammation process in a retinal artery -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:49879 ! occurs in Central retinal artery -property_value: CVDO:0000419 "An inflammation of the retinal artery." xsd:string - -[Term] -id: CVDO:0000412 -name: inflammation process in a vein -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:50723 ! occurs in Vein -property_value: CVDO:0000419 "An inflammation process occurring in a vein." xsd:string - -[Term] -id: CVDO:0000418 -name: fibrofatty replacement in a right ventricular myocardium -comment: A pathological process of fibrofatty replacement in the myocardium of the right cardiac ventricle. -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:7098 ! occurs in Right ventricle -relationship: BFO:0000167 FMA:9535 ! has participant at all times Myocardium of right ventricle - -[Term] -id: CVDO:0000420 -name: degenerated structure in a heart valve leaflet -def: "A disorder of degenerated structure in a heart valve leaflet." [] -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:7110 ! located in at all times Cardiac valve - -[Term] -id: CVDO:0000421 -name: degenerated structure in an aortic valve leaflet -intersection_of: CVDO:0000420 ! degenerated structure in a heart valve leaflet -intersection_of: BFO:0000082 FMA:7236 ! located in at all times Aortic valve -property_value: CVDO:0000419 "A disorder of degenerated structure in an aortic valve leaflet." xsd:string - -[Term] -id: CVDO:0000422 -name: degenerated structure in a mitral valve leaflet -intersection_of: CVDO:0000420 ! degenerated structure in a heart valve leaflet -intersection_of: BFO:0000082 FMA:7235 ! located in at all times Mitral valve -property_value: CVDO:0000419 "A disorder of degenerated structure in a mitral valve leaflet." xsd:string - -[Term] -id: CVDO:0000423 -name: degenerated structure in a tricuspid valve leaflet -intersection_of: CVDO:0000420 ! degenerated structure in a heart valve leaflet -intersection_of: BFO:0000082 FMA:7234 ! located in at all times Tricuspid valve -property_value: CVDO:0000419 "A (clinically abnormal) degenerated structure in a tricuspid valve leaflet." xsd:string - -[Term] -id: CVDO:0000424 -name: degenerated structure in a pulmonary valve leaflet -intersection_of: CVDO:0000420 ! degenerated structure in a heart valve leaflet -intersection_of: BFO:0000082 FMA:7246 ! located in at all times Pulmonary valve -property_value: CVDO:0000419 "A disorder of degenerated structure in a pulmonary valve leaflet." xsd:string - -[Term] -id: CVDO:0000426 -name: Barlow's syndrome -property_value: CVDO:0000419 "A mitral valve prolapse due to myxomatous proliferation in the mitral valve." xsd:string - -[Term] -id: CVDO:0000427 -name: fluid accumulation in the pericardial cavity -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:9869 ! occurs in Pericardium -property_value: CVDO:0000419 "A pathological process consisting in the abnormal accumulation of fluid in the pericardial cavity." xsd:string -property_value: CVDO:0000533 "A process of pericardial effusion leads to the disorder 'fluid in the pericardial cavity'." xsd:string - -[Term] -id: CVDO:0000435 -name: atherosclerotic ischemic cardiomyopathy -is_a: CVDO:0000558 ! ischemic cardiomyopathy -relationship: BFO:0000113 DOID:4248 ! has material basis at all times coronary stenosis -property_value: CVDO:0000419 "An ischemic cardiomyopathy due to coronary stenosis." xsd:string - -[Term] -id: CVDO:0000436 -name: paroxysmal atrial fibrillation -is_a: CVDO:0000092 ! atrial fibrillation (disease) -property_value: CVDO:0000419 "An atrial fibrillation disease that is characterized by an atrial fibrillation episode shorter than 7 days." xsd:string - -[Term] -id: CVDO:0000437 -name: persistent atrial fibrillation -is_a: CVDO:0000092 ! atrial fibrillation (disease) -property_value: CVDO:0000419 "An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does terminate by cardioversion." xsd:string - -[Term] -id: CVDO:0000439 -name: premature contraction (process) -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000441 -name: premature junctional contraction (process) -is_a: CVDO:0000439 ! premature contraction (process) - -[Term] -id: CVDO:0000442 -name: premature ventricular contraction (process) -is_a: CVDO:0000439 ! premature contraction (process) - -[Term] -id: CVDO:0000443 -name: sinoatrial arrest (process) -synonym: "sinus pause" EXACT [] -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000444 -name: sinus bradycardia (process) -is_a: CVDO:0000140 ! bradycardia (process) - -[Term] -id: CVDO:0000445 -name: tachycardia (process) -synonym: "tachyarrhythmia (process)" EXACT [] -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000447 -name: left atrial flutter (process) -is_a: CVDO:0000306 ! atrial flutter (process) - -[Term] -id: CVDO:0000448 -name: right atrial flutter (process) -is_a: CVDO:0000306 ! atrial flutter (process) - -[Term] -id: CVDO:0000449 -name: common atrial flutter (process) -is_a: CVDO:0000448 ! right atrial flutter (process) - -[Term] -id: CVDO:0000450 -name: atrioventricular nodal reentrant tachycardia (process) -is_a: CVDO:0000308 ! junctional tachycardia (process) - -[Term] -id: CVDO:0000453 -name: ventricular tachycardia (process) -is_a: CVDO:0000489 ! ventricular tachyarrhythmia (process) - -[Term] -id: CVDO:0000454 -name: monomorphic ventricular tachycardia (process) -is_a: CVDO:0000453 ! ventricular tachycardia (process) - -[Term] -id: CVDO:0000455 -name: torsades de pointes (process) -is_a: CVDO:0000453 ! ventricular tachycardia (process) - -[Term] -id: CVDO:0000456 -name: ventricular flutter (process) -is_a: CVDO:0000453 ! ventricular tachycardia (process) - -[Term] -id: CVDO:0000457 -name: inappropriate sinus tachycardia (process) -is_a: CVDO:0000445 ! tachycardia (process) - -[Term] -id: CVDO:0000458 -name: ventricular preexcitation (process) -is_a: CVDO:0000535 ! anomalous atrioventricular excitation (process) - -[Term] -id: CVDO:0000459 -name: coronary artery hardening -intersection_of: CVDO:0000223 ! artery hardening -intersection_of: BFO:0000066 FMA:49893 ! occurs in Coronary artery -property_value: CVDO:0000419 "A pathological process of a coronary artery hardening." xsd:string - -[Term] -id: CVDO:0000462 -name: accessory bundle -is_a: CVDO:0000015 ! heart disorder - -[Term] -id: CVDO:0000463 -name: atrioventricular accessory bundle -is_a: CVDO:0000462 ! accessory bundle -property_value: CVDO:0000419 "Accessory bundle that connects the atrium to a ventricle outside of the regular atrioventricular conduction system." xsd:string - -[Term] -id: CVDO:0000466 -name: impaired sinus node -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000470 -name: tachycardia-bradycardia syndrome -def: "A sick sinus syndrome characterized by sinus pauses and/or bradycardia episodes alternating with sinus or atrial tachycardia episodes." [] -is_a: DOID:13884 ! sick sinus syndrome - -[Term] -id: CVDO:0000471 -name: inappropriate sinus tachycardia (disease) - -[Term] -id: CVDO:0000472 -name: cardiac channelopathy -intersection_of: DOID:10273 ! heart conduction disease -intersection_of: BFO:0000113 CVDO:0000537 ! has material basis at all times cardiac ion channels disorder -property_value: CVDO:0000419 "A disease cause by a cardiac ion channel disorder." xsd:string - -[Term] -id: CVDO:0000473 -name: long QT syndrome -is_a: CVDO:0000472 ! cardiac channelopathy -property_value: CVDO:0000419 "A cardiac channelopathy in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. This is a rare disease." xsd:string - -[Term] -id: CVDO:0000474 -name: genetic cardiac channelopathy -intersection_of: CVDO:0000472 ! cardiac channelopathy -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A cardiac channelopathy that has a genetic origin." xsd:string - -[Term] -id: CVDO:0000475 -name: sinus bradycardia (disease) - -[Term] -id: CVDO:0000476 -name: left bundle branch block (process) -is_a: CVDO:0000319 ! left anterior fascicular block (process) - -[Term] -id: CVDO:0000477 -name: tachycardia (disease) -synonym: "tachyarrhythmia (disease)" EXACT [] - -[Term] -id: CVDO:0000479 -name: sinoatrial arrest (disease) - -[Term] -id: CVDO:0000480 -name: atrioventricular reciprocating tachycardia (disease) - -[Term] -id: CVDO:0000481 -name: ventricular tachycardia (disease) - -[Term] -id: CVDO:0000484 -name: ventricular flutter (disease) - -[Term] -id: CVDO:0000485 -name: torsades de pointes (disease) - -[Term] -id: CVDO:0000486 -name: monomorphic ventricular tachycardia (disease) - -[Term] -id: CVDO:0000487 -name: ventricular fibrillation (disease) - -[Term] -id: CVDO:0000489 -name: ventricular tachyarrhythmia (process) -is_a: CVDO:0000445 ! tachycardia (process) - -[Term] -id: CVDO:0000490 -name: atrioventricular reciprocating tachycardia (process) -is_a: CVDO:0000308 ! junctional tachycardia (process) - -[Term] -id: CVDO:0000493 -name: premature contraction (disease) - -[Term] -id: CVDO:0000495 -name: premature junctional contraction (disease) - -[Term] -id: CVDO:0000496 -name: premature ventricular contraction (disease) - -[Term] -id: CVDO:0000497 -name: cardiac chamber pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7095 ! occurs in Cardiac chamber -property_value: CVDO:0000419 "A pathological process occurring in a cardiac chamber." xsd:string - -[Term] -id: CVDO:0000499 -name: mitral valve disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7235 ! located in at all times Mitral valve -property_value: CVDO:0000419 "A disorder always located in the mitral valve." xsd:string - -[Term] -id: CVDO:0000500 -name: aortic valve disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7236 ! located in at all times Aortic valve -property_value: CVDO:0000419 "A disorder always located in the aortic valve." xsd:string - -[Term] -id: CVDO:0000501 -name: tricuspid valve disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7234 ! located in at all times Tricuspid valve -property_value: CVDO:0000419 "A disorder always located in the tricuspid valve." xsd:string - -[Term] -id: CVDO:0000502 -name: pulmonary valve disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7246 ! located in at all times Pulmonary valve -property_value: CVDO:0000419 "A disorder always located in the pulmonary valve." xsd:string - -[Term] -id: CVDO:0000503 -name: heart valve improper opening -def: "A pathological process of a heart valve improper opening." [] -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:7088 ! occurs in Heart -relationship: BFO:0000167 FMA:7110 ! has participant at all times Cardiac valve - -[Term] -id: CVDO:0000504 -name: aortic valve improper opening during left ventricular systole -intersection_of: CVDO:0000503 ! heart valve improper opening -intersection_of: BFO:0000132 CVDO:0000524 ! part of occurrent left ventricular systole -intersection_of: BFO:0000167 FMA:7236 ! has participant at all times Aortic valve - -[Term] -id: CVDO:0000505 -name: mitral valve narrowed opening during left ventricular diastole -intersection_of: CVDO:0000503 ! heart valve improper opening -intersection_of: BFO:0000132 CVDO:0000522 ! part of occurrent left ventricular diastole -intersection_of: BFO:0000167 FMA:7235 ! has participant at all times Mitral valve - -[Term] -id: CVDO:0000506 -name: pulmonary valve narrowed opening during right ventricular systole -intersection_of: CVDO:0000503 ! heart valve improper opening -intersection_of: BFO:0000132 CVDO:0000525 ! part of occurrent right ventricular systole -intersection_of: BFO:0000167 FMA:7246 ! has participant at all times Pulmonary valve - -[Term] -id: CVDO:0000507 -name: tricuspid valve narrowed opening during right ventricular diastole -intersection_of: CVDO:0000503 ! heart valve improper opening -intersection_of: BFO:0000132 CVDO:0000523 ! part of occurrent right ventricular diastole -intersection_of: BFO:0000167 FMA:7234 ! has participant at all times Tricuspid valve - -[Term] -id: CVDO:0000508 -name: coronary heart disease with stable angina -def: "A coronary heart disease leading to stable angina." [] - -[Term] -id: CVDO:0000509 -name: atherosclerotic acute coronary syndrome -intersection_of: DOID:8805 ! acute coronary syndrome -intersection_of: BFO:0000113 DOID:4248 ! has material basis at all times coronary stenosis -property_value: CVDO:0000419 "An acute coronary syndrome due to coronary stenosis." xsd:string - -[Term] -id: CVDO:0000510 -name: angina pectoris -is_a: CVDO:0000556 ! heart ischemia -property_value: CVDO:0000419 "A heart ischemia accompanied by pain." xsd:string -property_value: CVDO:0000533 "Angina pectoris is sometimes taken to refer to the pain itself, rather than to the pathological process behind it." xsd:string - -[Term] -id: CVDO:0000511 -name: stable angina pectoris -is_a: CVDO:0000510 ! angina pectoris -property_value: CVDO:0000419 "An angina that is not unstable." xsd:string - -[Term] -id: CVDO:0000512 -name: unstable angina pectoris -is_a: CVDO:0000510 ! angina pectoris -property_value: CVDO:0000419 "An angina that worsens. It has at least one of these three features:\n1. it occurs at rest (or with minimal exertion), usually lasting >10 min\n2. it is severe and of new onset (i.e., within the prior 4–6 weeks)\n3. it occurs with a crescendo pattern (i.e., distinctly more severe, prolonged, or frequent than before)." xsd:string - -[Term] -id: CVDO:0000513 -name: heart pathological process involving a mitral valve -def: "A heart pathological process that has a mitral valve as a participant." [] -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -intersection_of: BFO:0000167 FMA:7235 ! has participant at all times Mitral valve - -[Term] -id: CVDO:0000514 -name: heart pathological process involving an aortic valve -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -intersection_of: BFO:0000167 FMA:7236 ! has participant at all times Aortic valve -property_value: CVDO:0000419 "A heart pathological process that has an aortic valve as a participant." xsd:string - -[Term] -id: CVDO:0000515 -name: heart pathological process involving a tricuspid valve -def: "A heart pathological process that has a tricuspid valve as a participant." [] -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -intersection_of: BFO:0000167 FMA:7234 ! has participant at all times Tricuspid valve - -[Term] -id: CVDO:0000516 -name: heart pathological process involving a pulmonary valve -def: "A heart pathological process that has a pulmonary valve as a participant." [] -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7088 ! occurs in Heart -intersection_of: BFO:0000167 FMA:7246 ! has participant at all times Pulmonary valve - -[Term] -id: CVDO:0000517 -name: heart valve leaflet displacement into a cardiac chamber during ventricular diastole -intersection_of: CVDO:0000530 ! heart valve leaflet displacement into a cardiac chamber -intersection_of: BFO:0000132 CVDO:0000519 ! part of occurrent ventricular diastole - -[Term] -id: CVDO:0000518 -name: ventricular systole -is_a: CVDO:0000542 ! heart bodily process -relationship: BFO:0000167 FMA:7100 ! has participant at all times Cardiac ventricle - -[Term] -id: CVDO:0000519 -name: ventricular diastole -is_a: CVDO:0000542 ! heart bodily process -relationship: BFO:0000167 FMA:7100 ! has participant at all times Cardiac ventricle - -[Term] -id: CVDO:0000520 -name: atrial systole -is_a: CVDO:0000542 ! heart bodily process - -[Term] -id: CVDO:0000521 -name: atrial diastole -is_a: CVDO:0000542 ! heart bodily process - -[Term] -id: CVDO:0000522 -name: left ventricular diastole -is_a: CVDO:0000519 ! ventricular diastole -relationship: BFO:0000167 FMA:7101 ! has participant at all times Left ventricle - -[Term] -id: CVDO:0000523 -name: right ventricular diastole -is_a: CVDO:0000519 ! ventricular diastole -relationship: BFO:0000167 FMA:7098 ! has participant at all times Right ventricle - -[Term] -id: CVDO:0000524 -name: left ventricular systole -is_a: CVDO:0000518 ! ventricular systole -relationship: BFO:0000167 FMA:7101 ! has participant at all times Left ventricle - -[Term] -id: CVDO:0000525 -name: right ventricular systole -is_a: CVDO:0000518 ! ventricular systole -relationship: BFO:0000167 FMA:7098 ! has participant at all times Right ventricle - -[Term] -id: CVDO:0000526 -name: left atrial systole -is_a: CVDO:0000520 ! atrial systole - -[Term] -id: CVDO:0000527 -name: right atrial systole -is_a: CVDO:0000520 ! atrial systole - -[Term] -id: CVDO:0000528 -name: left atrial diastole -is_a: CVDO:0000521 ! atrial diastole - -[Term] -id: CVDO:0000529 -name: right atrial diastole -is_a: CVDO:0000521 ! atrial diastole - -[Term] -id: CVDO:0000530 -name: heart valve leaflet displacement into a cardiac chamber -def: "A pathological process of a heart valve being displaced into a cardiac chamber." [] -is_a: CVDO:0000210 ! heart valve improper close -relationship: BFO:0000066 FMA:7088 ! occurs in Heart -relationship: BFO:0000167 FMA:7110 ! has participant at all times Cardiac valve - -[Term] -id: CVDO:0000531 -name: fluid in the pericardial cavity -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:9869 ! located in at all times Pericardium -property_value: CVDO:0000419 "A disorder of fluid in the pericardial cavity." xsd:string - -[Term] -id: CVDO:0000532 -name: blood in the pericardial cavity -is_a: CVDO:0000531 ! fluid in the pericardial cavity -property_value: CVDO:0000419 "A disorder of blood in the pericardial cavity." xsd:string - -[Term] -id: CVDO:0000534 -name: heart conduction pathological process -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:83378 ! occurs in Conducting tissue of heart - -[Term] -id: CVDO:0000535 -name: anomalous atrioventricular excitation (process) -is_a: CVDO:0000310 ! cardiac arrhythmia (process) - -[Term] -id: CVDO:0000536 -name: ventricular preexcitation (disease) - -[Term] -id: CVDO:0000537 -name: cardiac ion channels disorder -is_a: CVDO:0000047 ! heart conduction disorder -property_value: CVDO:0000419 "A disorder in the heart conduction system that causes a disturbed function of ion channel subunits or the proteins that regulate them." xsd:string - -[Term] -id: CVDO:0000538 -name: pulmonary valve prolapse -property_value: CVDO:0000419 "A disease characterized by the displacement of a degenerated pulmonary valve leaflet into the right ventricle during diastole." xsd:string - -[Term] -id: CVDO:0000539 -name: impaired anterior division of left branch of atrioventricular bundle -is_a: CVDO:0000047 ! heart conduction disorder - -[Term] -id: CVDO:0000540 -name: ventricular tachyarrhythmia (disease) - -[Term] -id: CVDO:0000541 -name: inflammation process in a heart valve -intersection_of: CVDO:0000403 ! pathological inflammation process -intersection_of: BFO:0000066 FMA:7110 ! occurs in Cardiac valve -property_value: CVDO:0000419 "An inflammation process occurring in a heart valve." xsd:string - -[Term] -id: CVDO:0000542 -name: heart bodily process -is_a: OGMS:0000060 ! bodily process - -[Term] -id: CVDO:0000543 -name: genetic dilated cardiomyopathy -intersection_of: DOID:12930 ! dilated cardiomyopathy -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A dilated cardiomyopathy that has a genetic origin." xsd:string - -[Term] -id: CVDO:0000544 -name: genetic cardiomyopathy -intersection_of: CVDO:0000569 ! cardiomyopathy (2008 definition) -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A cardiomyopathy (2008) that has a genetic origin." xsd:string - -[Term] -id: CVDO:0000545 -name: embolus -comment: A disorder made of a detached, traveling intravascular matter (solid, liquid, or gaseous) carried by circulation. It is capable of creating an arterial occlusion at a site distant from its point of origin. -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:3710 ! located in at all times Vascular tree - -[Term] -id: CVDO:0000546 -name: inflammatory disease -property_value: CVDO:0000419 "A disease characterized by an inflammation process." xsd:string - -[Term] -id: CVDO:0000547 -name: myocardium pathological process -comment: A pathological process occurring in the myocardium. -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:9462 ! occurs in Myocardium - -[Term] -id: CVDO:0000548 -name: aorta pathological process -is_a: OGMS:0000061 ! pathological bodily process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:3734 ! occurs in Aorta -property_value: CVDO:0000419 "A pathological process involving or occuring in the aorta." xsd:string - -[Term] -id: CVDO:0000549 -name: aorta disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:3734 ! located in at all times Aorta -property_value: CVDO:0000419 "A disorder always located in the aorta." xsd:string - -[Term] -id: CVDO:0000550 -name: endocardium pathological process -is_a: OGMS:0000061 ! pathological bodily process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7280 ! occurs in Endocardium -property_value: CVDO:0000419 "A pathological process occuring in the endocardium." xsd:string - -[Term] -id: CVDO:0000551 -name: endocardium thickening -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:7280 ! occurs in Endocardium -property_value: CVDO:0000419 "A pathological process of thickening of the endocardium." xsd:string - -[Term] -id: CVDO:0000552 -name: endocardium disease -comment: A disease affecting the endocardium. - -[Term] -id: CVDO:0000553 -name: left ventricle disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7101 ! located in at all times Left ventricle -property_value: CVDO:0000419 "A disorder always located in the left heart ventricle." xsd:string - -[Term] -id: CVDO:0000554 -name: right ventricle disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7098 ! located in at all times Right ventricle -property_value: CVDO:0000419 "A disorder always located in the right heart ventricle." xsd:string - -[Term] -id: CVDO:0000555 -name: heart ventricle disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7100 ! located in at all times Cardiac ventricle -property_value: CVDO:0000419 "A disorder always located in a heart ventricle." xsd:string - -[Term] -id: CVDO:0000556 -name: heart ischemia -is_a: DOID:326 ! ischemia -property_value: CVDO:0000419 "An ischemia of the heart." xsd:string - -[Term] -id: CVDO:0000557 -name: vein pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:50723 ! occurs in Vein - -[Term] -id: CVDO:0000558 -name: ischemic cardiomyopathy -is_a: DOID:3394 ! ischemic heart disease -property_value: CVDO:0000419 "An ischemic heart disease leading to a dilatation and dysfunction of the left ventricle." xsd:string - -[Term] -id: CVDO:0000559 -name: material anatomical entity disorder -comment: A disorder located in an anatomical entity. -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:67165 ! located in at all times Material anatomical entity - -[Term] -id: CVDO:0000560 -name: material anatomical entity pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:67165 ! occurs in Material anatomical entity - -[Term] -id: CVDO:0000562 -name: cardiovascular system disorder -is_a: OGMS:0000045 ! disorder -intersection_of: OGMS:0000045 ! disorder -intersection_of: BFO:0000082 FMA:7161 ! located in at all times Cardiovascular system - -[Term] -id: CVDO:0000563 -name: cardiovascular system pathological process -is_a: OGMS:0000061 ! pathological bodily process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7161 ! occurs in Cardiovascular system - -[Term] -id: CVDO:0000564 -name: disease of material anatomical entity -comment: A disease that affects a material anatomical entity. -is_a: OGMS:0000031 ! disease - -[Term] -id: CVDO:0000567 -name: valvular cardiomyopathy -is_a: OGMS:0000031 ! disease -relationship: BFO:0000113 CVDO:0000500 ! has material basis at all times aortic valve disorder -property_value: CVDO:0000419 "An aortic valve stenosis leading to a hypertrophy or dilatation of the left ventricle and its dysfunction." xsd:string - -[Term] -id: CVDO:0000569 -name: cardiomyopathy (2008 definition) -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A heart disease in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality.\n(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)" xsd:string -property_value: CVDO:0000533 "Contemporary (e.g. Elliott et al. 2008) definitions of cardiomyopathy exclude ischemic cardiomyopathy, hypertensive cardiomyopathy and valvular cardiomyopathy." xsd:string - -[Term] -id: CVDO:0000570 -name: left ventricular myocardium contraction dysfunctional process -intersection_of: CVDO:0000571 ! myocardium contraction dysfunctional process -intersection_of: BFO:0000066 FMA:9558 ! occurs in Myocardium of left ventricle - -[Term] -id: CVDO:0000571 -name: myocardium contraction dysfunctional process -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:9462 ! occurs in Myocardium - -[Term] -id: CVDO:0000575 -name: left ventricle pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7101 ! occurs in Left ventricle -property_value: CVDO:0000533 "A pathological process occurring in the left heart ventricle." xsd:string - -[Term] -id: CVDO:0000576 -name: right ventricle pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7098 ! occurs in Right ventricle -property_value: CVDO:0000419 "A pathological process occurring in the right heart ventricle." xsd:string - -[Term] -id: CVDO:0000577 -name: inflammatory dilated cardiomyopathy -synonym: "inflammatory dilated cardiomyopathy" EXACT [] -is_a: DOID:12930 ! dilated cardiomyopathy -disjoint_from: CVDO:0000579 ! congenital heart disease -property_value: CVDO:0000419 "\"Inflammatory DCM is defined by the presence of chronic inflammatory cells in association with left ventricular dilatation and reduced ejection fraction\".\n(Elliott et al., 2008)" xsd:string - -[Term] -id: CVDO:0000578 -name: hypertensive cardiomyopathy -is_a: DOID:11516 ! hypertensive heart disease -property_value: CVDO:0000419 "A hypertensive heart disease leading to a hypertrophy and dysfunction of the left ventricle." xsd:string - -[Term] -id: CVDO:0000579 -name: congenital heart disease -is_a: DOID:114 ! heart disease -disjoint_from: DOID:0050431 ! arrhythmogenic right ventricular dysplasia -disjoint_from: DOID:11516 ! hypertensive heart disease -property_value: CVDO:0000419 "A heart disease existing at birth, or developping during the first month after birth." xsd:string - -[Term] -id: CVDO:0000580 -name: heart ventricle disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease affecting a heart ventricle." xsd:string - -[Term] -id: CVDO:0000581 -name: left ventricle disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease affecting a heart left ventricle." xsd:string - -[Term] -id: CVDO:0000582 -name: right ventricle disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease affecting a heart right ventricle." xsd:string - -[Term] -id: CVDO:0000583 -name: ventricular myocardium contraction dysfunctional process -intersection_of: CVDO:0000571 ! myocardium contraction dysfunctional process -intersection_of: BFO:0000066 FMA:12151 ! occurs in Myocardium of ventricle - -[Term] -id: CVDO:0000584 -name: right ventricular myocardium contraction dysfunctional process -is_a: CVDO:0000571 ! myocardium contraction dysfunctional process -intersection_of: CVDO:0000571 ! myocardium contraction dysfunctional process -intersection_of: BFO:0000066 FMA:9535 ! occurs in Myocardium of right ventricle - -[Term] -id: CVDO:0000585 -name: myocardium of left ventricle stiffening -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:9558 ! occurs in Myocardium of left ventricle - -[Term] -id: CVDO:0000586 -name: heart valve pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7110 ! occurs in Cardiac valve -property_value: CVDO:0000419 "A pathological process occurring in a heart valve." xsd:string - -[Term] -id: CVDO:0000587 -name: aortic valve pathological process -is_a: OGMS:0000061 ! pathological bodily process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7236 ! occurs in Aortic valve -property_value: CVDO:0000419 "A pathological process occurring in an aortic valve." xsd:string - -[Term] -id: CVDO:0000588 -name: mitral valve pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7235 ! occurs in Mitral valve -property_value: CVDO:0000419 "A pathological process occurring in a mitral valve." xsd:string - -[Term] -id: CVDO:0000589 -name: tricuspid valve pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7234 ! occurs in Tricuspid valve -property_value: CVDO:0000419 "A pathological process occurring in a tricuspid valve." xsd:string - -[Term] -id: CVDO:0000590 -name: pulmonary valve pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:7246 ! occurs in Pulmonary valve -property_value: CVDO:0000419 "A pathological process occurring in a pulmonary valve." xsd:string - -[Term] -id: CVDO:0000591 -name: myocardium disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease affecting the myocardium." xsd:string - -[Term] -id: CVDO:0000596 -name: genetic heart disease -intersection_of: DOID:114 ! heart disease -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A heart disease that has a genetic disorder." xsd:string - -[Term] -id: CVDO:0000597 -name: congenital disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease existing at birth, or developping during the first month after birth." xsd:string - -[Term] -id: CVDO:0000599 -name: coronary artery pathological process -intersection_of: OGMS:0000061 ! pathological bodily process -intersection_of: BFO:0000066 FMA:49893 ! occurs in Coronary artery - -[Term] -id: CVDO:0000600 -name: coronary artery smooth muscle constriction -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:49893 ! occurs in Coronary artery -property_value: CVDO:0000533 "A pathological process of coronary artery smooth muscle constriction." xsd:string - -[Term] -id: DOID:0000405 ! vascular tissue disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:0050431 ! arrhythmogenic right ventricular dysplasia -is_a: OGMS:0000031 ! disease -relationship: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A cardiomyopathy characterized by adipose and fibrosis infiltration in the right ventricular myocardium. It is caused by genetic defects of desmosomes (which are parts of the myocardium) and may result in arrhythmia." xsd:string - -[Term] -id: DOID:0050451 ! Brugada syndrome -is_a: CVDO:0000472 ! cardiac channelopathy -relationship: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death by ventricular tachyarrhytmia." xsd:string - -[Term] -id: DOID:0050644 ! generalized arterial calcification of infancy -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:0050645 ! arterial tortuosity syndrome -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:0050650 -name: familial atrial fibrillation -is_a: CVDO:0000092 ! atrial fibrillation (disease) -relationship: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder -property_value: CVDO:0000419 "An atrial fibrillation disease that has a genetic origin." xsd:string - -[Term] -id: DOID:0050700 ! cardiomyopathy (1995 definition) -property_value: CVDO:0000419 "Disease of the myocardium associated with cardiac dysfunction.\n(Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies)" xsd:string -property_value: CVDO:0000533 "DOID label \"cardiomyopathy\" was changed." xsd:string - -[Term] -id: DOID:0060000 ! infective endocarditis -property_value: CVDO:0000419 "An endocarditis caused by infection." xsd:string - -[Term] -id: DOID:0060068 -name: non-bacterial thrombotic endocarditis -synonym: "marantic endocarditis" EXACT [] -property_value: CVDO:0000533 "DOID label 'marantic endocarditis' was changed in CVDO (non-bacterial thrombotic endocarditis is a more common name)." xsd:string - -[Term] -id: DOID:10128 ! venous insufficiency -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:10230 ! aortic atherosclerosis - -[Term] -id: DOID:10234 ! histoplasmosis pericarditis -is_a: CVDO:0000036 ! fungal pericarditis - -[Term] -id: DOID:10272 -name: left anterior fascicular block (disease) -relationship: BFO:0000113 CVDO:0000539 ! has material basis at all times impaired anterior division of left branch of atrioventricular bundle -property_value: CVDO:0000533 "DOID label changed to 'left anterior fascicular block (disease)' for symmetry reasons with 'left posterior fascicular block (disease)'" xsd:string - -[Term] -id: DOID:10273 ! heart conduction disease -property_value: CVDO:0000419 "A disease affecting the conducting tissue of the heart." xsd:string - -[Term] -id: DOID:10314 ! endocarditis -property_value: CVDO:0000419 "A disease characterized by an inflammation of the endocardium." xsd:string - -[Term] -id: DOID:10392 ! anomalous atrioventricular excitation (disease) -property_value: CVDO:0000533 "DOID label 'anomalous atrioventricular excitation' was changed." xsd:string - -[Term] -id: DOID:10556 ! supine hypotensive syndrome -is_a: CVDO:0000234 ! compression disease - -[Term] -id: DOID:10591 ! pre-eclampsia -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:10763 ! hypertension -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:10880 ! iliac vein thrombophlebitis -is_a: DOID:3875 ! thrombophlebitis - -[Term] -id: DOID:112 ! esophageal varix -is_a: CVDO:0000214 ! vein disorder - -[Term] -id: DOID:11312 -name: Mobitz II second degree atrioventricular block (disease) -property_value: CVDO:0000533 "DOID label changed for homogeneization reasons." xsd:string - -[Term] -id: DOID:114 ! heart disease -property_value: CVDO:0000419 "A disease affecting the heart." xsd:string - -[Term] -id: DOID:11482 ! hemopericardium -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:115 ! cardiac tamponade -is_a: OGMS:0000031 ! disease -relationship: BFO:0000113 CVDO:0000531 ! has material basis at all times fluid in the pericardial cavity -property_value: CVDO:0000419 "A disease caused by the presence of fluid in the pericardial cavity (due to pericardial effusion), affecting negatively the heart's pumping function." xsd:string -property_value: CVDO:0000533 "In CVDO, cardiac tamponade is defined as *being caused* by a pericardial effusion, rather than as *being* a pericardial effusion." xsd:string - -[Term] -id: DOID:11502 ! mitral valve insufficiency -property_value: CVDO:0000419 "A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve." xsd:string - -[Term] -id: DOID:11516 ! hypertensive heart disease -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:11563 ! retinal vasculitis -property_value: CVDO:0000419 "A disease characterized by an inflammation of a retinal artery." xsd:string - -[Term] -id: DOID:11695 ! portal vein thrombosis -intersection_of: CVDO:0000217 ! thrombosis -intersection_of: BFO:0000066 FMA:66645 ! occurs in Portal vein -property_value: CVDO:0000419 "A thrombosis that occurs in a portal vein." xsd:string - -[Term] -id: DOID:11713 ! diabetic angiopathy -is_a: CVDO:0000231 ! ischemic disease - -[Term] -id: DOID:118 ! pericardial effusion - -[Term] -id: DOID:11840 ! coronary artery vasospasm -property_value: CVDO:0000419 "A coronary heart disease with coronary artery smooth muscle constriction." xsd:string - -[Term] -id: DOID:11847 ! coronary thrombosis -intersection_of: CVDO:0000217 ! thrombosis -intersection_of: BFO:0000066 FMA:49893 ! occurs in Coronary artery -property_value: CVDO:0000419 "A thrombosis occuring in a coronary artery." xsd:string - -[Term] -id: DOID:11984 ! hypertrophic cardiomyopathy -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "\"A heart disease with increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to cause the observed abnormality.\"\n(Elliott et al., 2008, European Heart Journal, 29, 270-276)" xsd:string - -[Term] -id: DOID:12010 ! ischemic optic neuropathy -is_a: CVDO:0000231 ! ischemic disease - -[Term] -id: DOID:12282 ! femoral vein thrombophlebitis -is_a: DOID:3875 ! thrombophlebitis - -[Term] -id: DOID:12326 ! chronic pulmonary heart disease -property_value: CVDO:0000419 "A cor pulmonale that has a chronic disease course during which the right ventricle becomes hypertrophied." xsd:string - -[Term] -id: DOID:1287 ! cardiovascular system disease -property_value: CVDO:0000419 "A disease affecting the cardiovascular system." xsd:string - -[Term] -id: DOID:12929 ! endocardial fibroelastosis -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown." xsd:string - -[Term] -id: DOID:12930 ! dilated cardiomyopathy -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment.\n(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)" xsd:string - -[Term] -id: DOID:12935 ! alcoholic cardiomyopathy -is_a: DOID:12930 ! dilated cardiomyopathy -property_value: CVDO:0000419 "A dilated cardiomyopathy resulting from alcohol intoxication." xsd:string - -[Term] -id: DOID:13209 ! right bundle branch block (disease) -relationship: BFO:0000113 CVDO:0000051 ! has material basis at all times impaired right branch of atrioventricular bundle - -[Term] -id: DOID:13241 ! Behcet's disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:13834 ! rheumatic tricuspid valve disease -is_a: CVDO:0000154 ! tricuspid valve disease - -[Term] -id: DOID:13884 ! sick sinus syndrome -is_a: DOID:10273 ! heart conduction disease -relationship: BFO:0000113 CVDO:0000466 ! has material basis at all times impaired sinus node -property_value: CVDO:0000419 "A heart conduction disease characterized by inappropriate sinus rates (e.g. sinus bradycardia or sinus pause)." xsd:string - -[Term] -id: DOID:14121 ! blue toe syndrome -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:14265 ! pulmonary valve insufficiency -property_value: CVDO:0000419 "A disease in which an abnormal structure in a pulmonary valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve." xsd:string - -[Term] -id: DOID:14557 ! primary pulmonary hypertension -is_a: DOID:6432 ! pulmonary hypertension - -[Term] -id: DOID:1461 ! cholesterol embolism -is_a: CVDO:0000225 ! embolism -property_value: CVDO:0000419 "An embolism due to an embolus made of cholesterol." xsd:string - -[Term] -id: DOID:1712 ! aortic valve stenosis -property_value: CVDO:0000419 "A disease in which some disorder of the aortic valve leads prevents it from opening properly during left ventricular systole, occasioning disturbance in the anterograd blood flow through the valve." xsd:string - -[Term] -id: DOID:1754 ! mitral valve stenosis -property_value: CVDO:0000419 "A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve." xsd:string - -[Term] -id: DOID:178 ! vascular disease -property_value: CVDO:0000419 "A disease affecting a blood vessel." xsd:string -property_value: CVDO:0000533 "Reorganization of the vascular diseases, and writing of Aristotelian definitions, is still ongoing." xsd:string - -[Term] -id: DOID:1787 ! pericarditis -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease characterized by an inflammation of the pericardium." xsd:string - -[Term] -id: DOID:1869 ! chronic rheumatic pericarditis -property_value: CVDO:0000419 "A chronic pericarditis due to rheumatic fever." xsd:string - -[Term] -id: DOID:1929 ! supravalvular aortic stenosis -is_a: CVDO:0000597 ! congenital disease -property_value: CVDO:0000419 "A congenital disease involving the narrowing (stenosis) of aorta, hindering the opening of the aortic valve." xsd:string -property_value: CVDO:0000533 "Supravalvular aortic stenosis is not classified as an aortic valve stenosis: although the narrowing of the section of the aorta at the exit of the aortic valve implies some improper opening of the aortic valve, the aortic valve is (in general) healthy (there is no disorder nor pathological process inside it). However, this improper opening of the aortic valve is a pathological process that happens inside the heart; therefore, supravalvular aortic stenosis is classified as a heart disease." xsd:string - -[Term] -id: DOID:1936 ! atherosclerosis -is_a: DOID:2349 ! arteriosclerosis - -[Term] -id: DOID:224 ! transient cerebral ischemia -intersection_of: DOID:2316 ! brain ischemia -intersection_of: BFO:0000132 OGMS:0000066 ! part of occurrent transient disease course -property_value: CVDO:0000419 "A brain ischemia that is part of a transient disease course." xsd:string - -[Term] -id: DOID:2349 ! arteriosclerosis -is_a: DOID:2868 ! arterial occlusive disease - -[Term] -id: DOID:2388 ! renal vascular disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:2403 ! aneurysm (disease) -intersection_of: OGMS:0000031 ! disease -intersection_of: BFO:0000113 CVDO:0000226 ! has material basis at all times aneurysm (disorder) -property_value: CVDO:0000419 "A disposition that an aneurysm disorder will lead to pathological processes." xsd:string -property_value: CVDO:0000533 "DOID label 'aneurysm disease' changed for homogeneization purpose in CVDO." xsd:string - -[Term] -id: DOID:2462 ! retinal vascular disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:2494 ! angiodysplasia -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:255 ! hemangioma -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:272 ! hepatic vascular disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:2868 ! arterial occlusive disease -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:3103 ! thoracic outlet syndrome -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:325 ! spinal cord vascular disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:326 ! ischemia -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:3710 ! occurs in Vascular tree -property_value: CVDO:0000419 "A pathological process of restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism." xsd:string - -[Term] -id: DOID:3363 ! coronary arteriosclerosis - -[Term] -id: DOID:3393 ! coronary heart disease -is_a: DOID:3394 ! ischemic heart disease -property_value: CVDO:0000419 "An ischemic heart disease with narrowing of the coronary arteries." xsd:string - -[Term] -id: DOID:3394 ! ischemic heart disease -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease characterized by reduced blood supply to the heart, occasioning pathological processes in the heart." xsd:string - -[Term] -id: DOID:341 ! peripheral vascular disease -is_a: CVDO:0000231 ! ischemic disease - -[Term] -id: DOID:3410 ! carotid artery thrombosis -relationship: BFO:0000066 FMA:3939 ! occurs in Common carotid artery -property_value: CVDO:0000419 "A thrombosis occurring in a carotid artery." xsd:string - -[Term] -id: DOID:3454 ! brain infarction -comment: An infarction occurring in the brain. -intersection_of: CVDO:0000276 ! infarction -intersection_of: BFO:0000066 FMA:50801 ! occurs in Brain - -[Term] -id: DOID:3455 ! cerebrovascular accident -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000066 FMA:45840 ! occurs in Arterial tree organ -property_value: CVDO:0000419 "A pathological process of disturbance in the blood supply to the brain, causing a loss of brain function." xsd:string - -[Term] -id: DOID:3572 ! intracranial sinus thrombosis -relationship: BFO:0000066 FMA:50762 ! occurs in Dural venous sinus -property_value: CVDO:0000419 "A thrombosis that occurs in a dural venous sinus." xsd:string - -[Term] -id: DOID:3574 ! lateral sinus thrombosis -is_a: DOID:3572 ! intracranial sinus thrombosis -relationship: BFO:0000066 FMA:50763 ! occurs in Transverse sinus -property_value: CVDO:0000419 "A thrombosis that occurs in a transverse sinus." xsd:string - -[Term] -id: DOID:3669 ! intermittent claudication -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:3825 ! Shwartzman phenomenon -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:384 ! Wolff-Parkinson-White syndrome - -[Term] -id: DOID:3875 ! thrombophlebitis -is_a: OGMS:0000031 ! disease - -[Term] -id: DOID:3951 ! acute myocarditis -intersection_of: DOID:820 ! myocarditis -intersection_of: BFO:0000054 OGMS:0000094 ! realized in acute disease course -property_value: CVDO:0000419 "A myocarditis with an acute disease course." xsd:string - -[Term] -id: DOID:396 ! Loeffler endocarditis - -[Term] -id: DOID:397 ! restrictive cardiomyopathy -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A cardiomyopathy (2008) characterized by increased stiffness of the left ventricular myocardium and decreased compliance of the left ventricle (which is restricted from stretching and filling with blood properly), in the absence of dilated cardiomyopathy and hypertrophic cardiomyopathy." xsd:string - -[Term] -id: DOID:4078 ! tricuspid valve stenosis -property_value: CVDO:0000419 "A disease in which some disorder of a tricuspid valve prevents it from opening properly during right ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve." xsd:string - -[Term] -id: DOID:4079 ! heart valve disease -property_value: CVDO:0000419 "A disease affecting a valve of the heart." xsd:string - -[Term] -id: DOID:4080 ! tricuspid valve insufficiency -property_value: CVDO:0000419 "A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve." xsd:string - -[Term] -id: DOID:4193 ! intracranial thrombosis -is_a: CVDO:0000217 ! thrombosis -relationship: BFO:0000066 FMA:50801 ! occurs in Brain -property_value: CVDO:0000419 "A thrombosis occurring in the brain." xsd:string - -[Term] -id: DOID:4248 ! coronary stenosis -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:49893 ! located in at all times Coronary artery -property_value: CVDO:0000419 "A disorder of atheromous plaques in a coronary artery." xsd:string - -[Term] -id: DOID:4372 ! intracranial embolism -is_a: CVDO:0000225 ! embolism - -[Term] -id: DOID:4562 ! subacute bacterial endocarditis -is_a: CVDO:0000010 ! bacterial endocarditis -property_value: CVDO:0000419 "A bacterial endocarditis characterized by a slow process of infection." xsd:string - -[Term] -id: DOID:471 ! skin hemangioma -is_a: DOID:255 ! hemangioma - -[Term] -id: DOID:484 ! vascular hemostatic disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:519 ! aortitis -property_value: CVDO:0000419 "A disease characterized by an inflammation of the aorta." xsd:string - -[Term] -id: DOID:520 ! aortic disease -property_value: CVDO:0000419 "A disease affecting the aorta." xsd:string - -[Term] -id: DOID:5232 ! aortic valve prolapse -property_value: CVDO:0000419 "A disease characterized by the displacement of a degenerated aortic valve leaflet into the left ventricle during diastole." xsd:string - -[Term] -id: DOID:525 ! central nervous system vasculitis - -[Term] -id: DOID:5453 ! pulmonary venoocclusive disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:5644 ! tricuspid valve prolapse -property_value: CVDO:0000419 "A disease characterized by the displacement of a degenerated tricuspid valve leaflet into the right atrium during systole." xsd:string - -[Term] -id: DOID:57 ! aortic valve insufficiency -property_value: CVDO:0000419 "A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve." xsd:string - -[Term] -id: DOID:5749 ! pulmonary valve disease -property_value: CVDO:0000419 "A disease affecting the pulmonary valve of the heart." xsd:string - -[Term] -id: DOID:5805 ! subvalvular aortic stenosis -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000533 "This refers to a narrowing of the section of the left ventricle below the aortic valve; therefore, this was not classified as an aortic valve stenosis in CVDO." xsd:string - -[Term] -id: DOID:5844 ! myocardial infarction -intersection_of: CVDO:0000276 ! infarction -intersection_of: BFO:0000066 FMA:9462 ! occurs in Myocardium -property_value: CVDO:0000419 "An infarction occurring in the myocardium." xsd:string - -[Term] -id: DOID:6000 ! congestive heart failure -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease characterized by the inability of the heart to pump a sufficient amount of blood throughout the body." xsd:string - -[Term] -id: DOID:61 ! mitral valve disease -property_value: CVDO:0000419 "A disease affecting the mitral valve of the heart." xsd:string - -[Term] -id: DOID:62 ! aortic valve disease -property_value: CVDO:0000419 "A disease affecting the aortic valve of the heart." xsd:string - -[Term] -id: DOID:630 ! genetic disease -intersection_of: OGMS:0000031 ! disease -intersection_of: BFO:0000113 OGMS:0000047 ! has material basis at all times genetic disorder - -[Term] -id: DOID:6420 ! pulmonary valve stenosis -property_value: CVDO:0000419 "A disease in which some disorder of a pulmonary valve prevents it from opening properly during right ventricular systole, occasioning disturbance in the anterograd blood flow through the valve." xsd:string - -[Term] -id: DOID:6712 ! anterior spinal artery syndrome -is_a: DOID:325 ! spinal cord vascular disease - -[Term] -id: DOID:6713 ! cerebrovascular disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:682 ! compartment syndrome -is_a: CVDO:0000231 ! ischemic disease - -[Term] -id: DOID:799 ! varicose veins -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:820 ! myocarditis -property_value: CVDO:0000419 "A disease characterized by an inflammation of the myocardium." xsd:string - -[Term] -id: DOID:8514 ! acute pulmonary heart disease -equivalent_to: DOID:8517 ! acute cor pulmonale -property_value: CVDO:0000419 "A cor pulmonale that has an acute disease course during which the right ventricle becomes dilated." xsd:string -property_value: CVDO:0000533 "'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO." xsd:string - -[Term] -id: DOID:8515 ! cor pulmonale -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000419 "A disease characterized by a dilatation or hypertrophy of the myocardium of right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs, involving a failure of the right side of the heart." xsd:string -property_value: CVDO:0000533 "Although the 1995 classification of cardiomyopathies did not include cor pulmonale, it should have included it, given the definition of cardiomyopathy it adopted." xsd:string - -[Term] -id: DOID:8516 ! pulmonary embolism and infarction -is_a: OGMS:0000061 ! pathological bodily process -relationship: BFO:0000117 CVDO:0000276 ! has occurrent part infarction -relationship: BFO:0000117 DOID:9477 ! has occurrent part pulmonary embolism -property_value: CVDO:0000419 "A pathological process consisting in a pulmonary embolism and an infarction that follows." xsd:string - -[Term] -id: DOID:8517 ! acute cor pulmonale -property_value: CVDO:0000533 "'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO." xsd:string - -[Term] -id: DOID:864 ! phlebitis -property_value: CVDO:0000419 "A disease characterized by an inflammation of a vein." xsd:string - -[Term] -id: DOID:865 ! vasculitis -property_value: CVDO:0000419 "A disease characterized by an inflammation of a blood vessel." xsd:string - -[Term] -id: DOID:866 ! vein disease - -[Term] -id: DOID:8725 ! vascular dementia -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:8805 ! acute coronary syndrome -is_a: DOID:3393 ! coronary heart disease -relationship: BFO:0000054 OGMS:0000094 ! realized in acute disease course -property_value: CVDO:0000419 "A coronary heart disease with an acute disease course." xsd:string -property_value: CVDO:0000533 "DOID label 'intermediate coronary syndrome' was changed." xsd:string - -[Term] -id: DOID:8861 ! subvalvular pulmonary stenosis -synonym: "pulmonary subvalvular stenosis" EXACT [] -is_a: OGMS:0000031 ! disease -property_value: CVDO:0000533 "DOID label 'pulmonary subvalvular stenosis' was changed for homogeneization with 'subvalvular aortic stenosis'." xsd:string - -[Term] -id: DOID:9286 ! priapism -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:9428 ! intracranial hypertension -is_a: DOID:10763 ! hypertension - -[Term] -id: DOID:9477 ! pulmonary embolism -intersection_of: CVDO:0000225 ! embolism -intersection_of: BFO:0000066 FMA:66326 ! occurs in Pulmonary artery -property_value: CVDO:0000419 "An embolism that occurs in a pulmonary artery." xsd:string - -[Term] -id: DOID:9540 ! vascular skin disease -is_a: CVDO:0000267 ! vascular disease - unclassified by CVDO - -[Term] -id: DOID:9768 ! heart aneurysm -is_a: OGMS:0000045 ! disorder -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: DOID:988 ! mitral valve prolapse -property_value: CVDO:0000419 "A disease characterized by the displacement of a degenerated mitral valve leaflet into the left atrium during systole." xsd:string - -[Term] -id: DOID:989 ! heart valve prolapse -property_value: CVDO:0000419 "A disease characterized by the displacement of a degenerated heart valve leaflet during systole." xsd:string - -[Term] -id: DOID:9892 ! Marable's syndrome -is_a: CVDO:0000234 ! compression disease - -[Term] -id: FMA:12151 ! Myocardium of ventricle -relationship: BFO:0000082 FMA:7100 ! located in at all times Cardiac ventricle - -[Term] -id: FMA:13256 ! Wall of cardiac chamber -relationship: BFO:0000082 FMA:7095 ! located in at all times Cardiac chamber - -[Term] -id: FMA:3710 ! Vascular tree -relationship: BFO:0000082 FMA:7161 ! located in at all times Cardiovascular system - -[Term] -id: FMA:50722 ! Region of vascular tree organ -relationship: BFO:0000082 FMA:3710 ! located in at all times Vascular tree - -[Term] -id: FMA:67165 ! Material anatomical entity -is_a: BFO:0000040 ! material entity -property_value: CVDO:0000533 "This class was relocated as a son of BFO 'Material entity', and BFO 2.0 'located in at all times' relations were added between relevant FMA classes; they should ultimately be replaced by a genuine version of FMA using BFO 2.0 relations." xsd:string - -[Term] -id: FMA:7088 ! Heart -relationship: BFO:0000082 FMA:7161 ! located in at all times Cardiovascular system - -[Term] -id: FMA:7095 ! Cardiac chamber -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: FMA:7110 ! Cardiac valve -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: FMA:7280 ! Endocardium -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: FMA:83378 ! Conducting tissue of heart -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: FMA:86044 ! Region of myocardium -relationship: BFO:0000082 FMA:9462 ! located in at all times Myocardium - -[Term] -id: FMA:86187 ! Segment of arterial tree organ -relationship: BFO:0000082 FMA:45840 ! located in at all times Arterial tree organ - -[Term] -id: FMA:86188 ! Segment of venous tree organ -relationship: BFO:0000082 FMA:14284 ! located in at all times Venous tree organ - -[Term] -id: FMA:9462 ! Myocardium -relationship: BFO:0000082 FMA:7088 ! located in at all times Heart - -[Term] -id: FMA:9535 ! Myocardium of right ventricle -relationship: BFO:0000082 FMA:7098 ! located in at all times Right ventricle - -[Term] -id: FMA:9558 ! Myocardium of left ventricle -relationship: BFO:0000082 FMA:7101 ! located in at all times Left ventricle - -[Term] -id: FMA:9869 ! Pericardium -relationship: BFO:0000082 FMA:7161 ! located in at all times Cardiovascular system - -[Term] -id: OGMS:0000031 ! disease -is_a: BFO:0000016 ! disposition -property_value: CVDO:0000419 "In order to obtain the taxonomy of diseases / disorders / pathological process in CVDO, it is necessary to use the reasoner first and to look at the inferred class hierarchy." xsd:string - -[Term] -id: OGMS:0000045 ! disorder -is_a: BFO:0000040 ! material entity - -[Term] -id: OGMS:0000059 ! etiological process -is_a: BFO:0000015 ! process - -[Term] -id: OGMS:0000060 ! bodily process -is_a: BFO:0000015 ! process - -[Term] -id: OGMS:0000061 ! pathological bodily process -is_a: OGMS:0000060 ! bodily process - -[Term] -id: OGMS:0000063 ! disease course -is_a: BFO:0000015 ! process - -[Term] -id: OGMS:0000078 ! pathological anatomical structure -is_a: BFO:0000040 ! material entity - -[Typedef] -id: BFO:0000066 ! occurs in -property_value: CVDO:0000533 "CVDO adds the property chain that if A occurs_in B and B located_in_at_all_times C, then A occurs_in C. This is used for a few inferences in the ontology, but CVDO can be used without problem without this property chain." xsd:string -transitive_over: BFO:0000082 ! located in at all times - diff --git a/cvdo.owl b/cvdo.owl index 1d53768..3f3786e 100644 --- a/cvdo.owl +++ b/cvdo.owl @@ -1,6 +1,6 @@ - - - - - Adrien Barton Arnaud Rosier Jean-François Ethier @@ -42,6 +38,29 @@ + + + + Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. + Really of interest to developers only + BFO OWL specification label + + + + + + + + + Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 + Person:Alan Ruttenberg + Really of interest to developers only + BFO CLIF specification label + + + + + @@ -62,6 +81,181 @@ + + + + editor preferred term + + The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) + PERSON:Daniel Schober + GROUP:OBI:<http://purl.obolibrary.org/obo/obi> + + editor preferred term + + + + + + + + + example of usage + + + + + + + + has curation status + PERSON:Alan Ruttenberg + PERSON:Bill Bug + PERSON:Melanie Courtot + OBI_0000281 + has curation status + + + + + + + + definition + + The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. + PERSON:Daniel Schober + GROUP:OBI:<http://purl.obolibrary.org/obo/obi> + + definition + definition + + + + + + + + editor note + + An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. + PERSON:Daniel Schober + GROUP:OBI:<http://purl.obfoundry.org/obo/obi> + + editor note + editor note + + + + + + + + definition editor + + Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people + PERSON:Daniel Schober + GROUP:OBI:<http://purl.obolibrary.org/obo/obi> + + definition editor + definition editor + term editor + + + + + + + + + alternative term + + + + + + + + definition source + + formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 + PERSON:Daniel Schober + GROUP:OBI:<http://purl.obolibrary.org/obo/obi> + Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w + + definition source + definition source + + + + + + + + curator note + + An administrative note of use for a curator but of no use for a user + PERSON:Alan Ruttenberg + + curator note + curator note + + + + + + + + + imported from + + + + + + + + + elucidation + + + + + + + + + has associated axiom(nl) + + + + + + + + + has associated axiom(fol) + + + + + + + + + has axiom label + + + + + + + + gram-positive bacterial infectious disease + + + + + @@ -74,6 +268,24 @@ + + + + + + + + + + + + + + + + + + @@ -86,9 +298,101 @@ + + + + subset_property + + + + + + + + + + + + + + + + + + + + has_alternative_id + + + + + + + + database_cross_reference + + + + - + + has_exact_synonym + + + + + + + + has_obo_namespace + + + + + + + + has_related_synonym + + + + + + + + + + + + + + in_subset + + + + + + + + + + + + + + + + + + + + + + + + + @@ -103,63 +407,3517 @@ + + + + + + + inheres-in_at + inheresInAt + b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'inheres in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'inheres in@en(x,y,t)'. + BFO 2 Reference: Inherence is a subrelation of s-depends_on which holds between a dependent continuant and an independent continuant that is not a spatial region. Since dependent continuants cannot migrate from one independent continuant bearer to another, it follows that if b s-depends_on independent continuant c at some time, then b s-depends_on c at all times at which a exists. Inherence is in this sense redundantly time-indexed.For example, consider the particular instance of openness inhering in my mouth at t as I prepare to take a bite out of a donut, followed by a closedness at t+1 when I bite the donut and start chewing. The openness instance is then shortlived, and to say that it s-depends_on my mouth at all times at which this openness exists, means: at all times during this short life. Every time you make a fist, you make a new (instance of the universal) fist. (Every time your hand has the fist-shaped quality, there is created a new instance of the universal fist-shaped quality.) + BFO2 Reference: independent continuant that is not a spatial region + BFO2 Reference: specifically dependent continuant + (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002] + + inheres in at all times + + + + + + + + + + + + + + + + + + + + + + + + + b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002]) + + + + + + (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002] + + + + + + + + + + + + bearer-of_st + bearerOfAt + b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'bearer of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'bearer of@en'(x,y,t) + BFO2 Reference: independent continuant that is not a spatial region + BFO2 Reference: specifically dependent continuant + (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004] + + bearer of at some time + + + + + + + + + + + + + + + + + + + + + + + + + b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) + + + + + + (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004] + + + + + - + + + + + realized-in + realizedIn + [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) + if a realizable entity b is realized in a process p, then p stands in the has_participant relation to the bearer of b. (axiom label in BFO2 Reference: [106-002]) + (forall (x y z t) (if (and (RealizableEntity x) (Process y) (realizesAt y x t) (bearerOfAt z x t)) (hasParticipantAt y z t))) // axiom label in BFO2 CLIF: [106-002] + + realized in + + + + + + + + + + + + + + + + + if a realizable entity b is realized in a process p, then p stands in the has_participant relation to the bearer of b. (axiom label in BFO2 Reference: [106-002]) + + + + + + (forall (x y z t) (if (and (RealizableEntity x) (Process y) (realizesAt y x t) (bearerOfAt z x t)) (hasParticipantAt y z t))) // axiom label in BFO2 CLIF: [106-002] + + - + + + + realizes + realizes + to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) + (forall (x y t) (if (realizesAt x y t) (and (Process x) (or (Disposition y) (Role y)) (exists (z) (and (MaterialEntity z) (hasParticipantAt x z t) (bearerOfAt z y t)))))) // axiom label in BFO2 CLIF: [059-003] + + realizes + + + + + + + + + + + + + + + + + to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) + + + + + + (forall (x y t) (if (realizesAt x y t) (and (Process x) (or (Disposition y) (Role y)) (exists (z) (and (MaterialEntity z) (hasParticipantAt x z t) (bearerOfAt z y t)))))) // axiom label in BFO2 CLIF: [059-003] + + + + + + + + + + + + participates-in_st + participatesInAt + [copied from inverse property 'has participant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t) + [copied from inverse property 'has participant at some time'] BFO 2 Reference: Spatial regions do not participate in processes. + [copied from inverse property 'has participant at some time'] BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant + [copied from inverse property 'has participant at some time'] BFO2 Reference: process + [copied from inverse property 'has participant at some time'] has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003]) + + participates in at some time + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + has-participant_st + hasParticipantAt + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t) + BFO 2 Reference: Spatial regions do not participate in processes. + BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant + BFO2 Reference: process + has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003]) + if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003]) + if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003]) + if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001]) + if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001]) + if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001]) + (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003] + (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003] + (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001] + (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001] + (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001] + + has participant at some time + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003]) + + + + + + if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003]) + + + + + + if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003]) + + + + + + if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001]) + + + + + + if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001]) + + + + + + if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001]) + + + + + + (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003] + + + + + + (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001] + + + + + + + + + + + + concretized-by_st + [copied from inverse property 'concretizes at some time'] You may concretize a piece of software by installing it in your computer + [copied from inverse property 'concretizes at some time'] You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head. + [copied from inverse property 'concretizes at some time'] you may concretize a poem as a pattern of memory traces in your head + [copied from inverse property 'concretizes at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t) + [copied from inverse property 'concretizes at some time'] b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002]) + + concretized by at some time + + + + + + + + + + + + + + + + + + + + + + concretizes_st + concretizesAt + You may concretize a piece of software by installing it in your computer + You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head. + you may concretize a poem as a pattern of memory traces in your head + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t) + b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002]) + if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001]) + (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002] + (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001] + + concretizes at some time + + + + + + + + + + + + + + + + + b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002]) + + + + + + if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001]) + + + + + + (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002] + + + + + + (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001] + + + + + + occurs-in + occursIn CVDO adds the property chain that if A occurs_in B and B located_in_at_all_times C, then A occurs_in C. This is used for a few inferences in the ontology, but CVDO can be used without problem without this property chain. + b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t [XXX-001 + + occurs in + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + contains-process + containsProcess + [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t [XXX-001 + + contains process + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + s-depends-on_at + specificallyDependsOn + A pain s-depends_on the organism that is experiencing the pain + a gait s-depends_on the walking object. (All at some specific time.) + a shape s-depends_on the shaped object + one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head + one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism + one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell + one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant + one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question + one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command + one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat + one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs + reciprocal s-dependence between occurrents: a process of buying and the associated process of selling + reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas + reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces + the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball + the one-sided dependence of an occurrent on an independent continuant: handwave on a hand + the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45 + the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45 + the two-sided reciprocal s-dependence of the roles of husband and wife [20 + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'specifically depends on at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'specifically depends on@en(x,y,t)'. + BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28 + BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20 + BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place. + BFO2 Reference: specifically dependent continuant\; process; process boundary + To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64 + If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001]) + If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001]) + If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002]) + an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002]) + if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002]) + (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002] + (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002] + (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001] + (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002] + (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001] + + specifically depends on at all times + + + + + If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001]) + + + + + + If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001]) + + + + + + If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002]) + + + + + + an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002]) + + + + + + if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002]) + + + + + + (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002] + + + + + + (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002] + + + + + + (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001] + + + + + + (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002] + + + + + + (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001] + + + + + + + + + + + f-of_at + functionOfAt + a function_of b at t =Def. a is a function and a inheres_in b at t. (axiom label in BFO2 Reference: [067-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'function of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'function of@en(x,y,t)'. + (iff (functionOf a b t) (and (Function a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [067-001] + + function of at all times + + + + + + + + + + + a function_of b at t =Def. a is a function and a inheres_in b at t. (axiom label in BFO2 Reference: [067-001]) + + + + + + (iff (functionOf a b t) (and (Function a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [067-001] + + + + + + + + + + + q-of_at + qualityOfAt + b quality_of c at t = Def. b is a quality & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [056-002]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'quality of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'quality of@en(x,y,t)'. + (iff (qualityOfAt a b t) (and (Quality a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [056-002] + + quality of at all times + + + + + + + + + + + b quality_of c at t = Def. b is a quality & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [056-002]) + + + + + + (iff (qualityOfAt a b t) (and (Quality a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [056-002] + + + + + + + + + + + r-of_at + roleOfAt + a role_of b at t =Def. a is a role and a inheres_in b at t. (axiom label in BFO2 Reference: [065-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'role of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'role of@en(x,y,t)'. + (iff (roleOfAt a b t) (and (Role a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [065-001] + + role of at all times + + + + + + + + + + + a role_of b at t =Def. a is a role and a inheres_in b at t. (axiom label in BFO2 Reference: [065-001]) + + + + + + (iff (roleOfAt a b t) (and (Role a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [065-001] + + - + + + + located-in_at + locatedInAt + Mary located_in Salzburg + the Empire State Building located_in New York. + this portion of cocaine located_in this portion of blood + this stem cell located_in this portion of bone marrow + your arm located_in your body + b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'located in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'located in@en(x,y,t)'. + BFO2 Reference: independent continuant + Located_in is transitive. (axiom label in BFO2 Reference: [046-001]) + for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001]) + for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001]) + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001] + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001] + (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001] + (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001] + + located in at all times + + + + + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001] + + + + + + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001] + + + + + + (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001] + + + + + + (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001] + + + + + + b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001]) + + + + + + Located_in is transitive. (axiom label in BFO2 Reference: [046-001]) + + + + + + for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001]) + + + + + + for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001]) + + + + + + + + + + + + located-at-r_st + occupiesSpatialRegionAt + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t) + BFO2 Reference: independent continuant + BFO2 Reference: spatial region + b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002]) + every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002]) + if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001]) + (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002] + (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002] + (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001] + + occupies spatial region at some time + + + + + + + + + + + + + + + + + b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002]) + + + + + + every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002]) + + + + + + if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001]) + + + + + + (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002] + + + + + + (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002] + + + + + + (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001] + + + + + + + + + + + + g-depends-on_st + genericallyDependsOn + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'generically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'generically depends on@en'(x,y,t) + BFO2 Reference: generically dependent continuant + BFO2 Reference: independent continuant + b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002]) + if b g-depends_on c at some time t, then b g-depends_on something at all times at which b exists. (axiom label in BFO2 Reference: [073-001]) + (forall (x y) (if (exists (t) (genericallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (exists (z) (genericallyDependsOnAt x z t_1)))))) // axiom label in BFO2 CLIF: [073-001] + + generically depends on at some time + + + + + + + + + + + + + + + + + + + + + + + + + b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002]) + + + + + + if b g-depends_on c at some time t, then b g-depends_on something at all times at which b exists. (axiom label in BFO2 Reference: [073-001]) + + + + + + (forall (x y) (if (exists (t) (genericallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (exists (z) (genericallyDependsOnAt x z t_1)))))) // axiom label in BFO2 CLIF: [073-001] + + + + + + + + + + + has-f_st + hasFunctionAt + a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has function at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has function@en'(x,y,t) + (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001] + + has function at some time + + + + + + + + + + + a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001]) + + + + + + (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001] + + + + + + + + + + + has-q_st + + has quality at some time + + + + + + + + + + + + + + + + has-r_st + hasRoleAt + a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has role at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has role@en'(x,y,t) + (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001] + + has role at some time + + + + + + + + + + + a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001]) + + + + + + (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001] + + + + + + + + + + + + + + + has-g-dep_st + [copied from inverse property 'generically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'generically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'generically depends on@en'(x,y,t) + [copied from inverse property 'generically depends on at some time'] BFO2 Reference: generically dependent continuant + [copied from inverse property 'generically depends on at some time'] BFO2 Reference: independent continuant + [copied from inverse property 'generically depends on at some time'] b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002]) + + has generic dependent at some time + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + d-of_at + dispositionOfAt + a disposition_of b at t =Def. a is a disposition and a inheres_in b at t. (axiom label in BFO2 Reference: [066-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'disposition of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'disposition of@en(x,y,t)'. + (iff (dispositionOf a b t) (and (Disposition a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [066-001] + + disposition of at all times + + + + + + + + + + + a disposition_of b at t =Def. a is a disposition and a inheres_in b at t. (axiom label in BFO2 Reference: [066-001]) + + + + + + (iff (dispositionOf a b t) (and (Disposition a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [066-001] + + + + + + + + + + + + exists-at + existsAt + BFO2 Reference: entity + BFO2 Reference: temporal region + b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002]) + + exists at + + + + + + + + + + + + + + + + + b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002]) + + + + + + + + + + + + c-has-part_at + hasContinuantPartAt + [copied from inverse property 'part of continuant at all times that whole exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t) + b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'. + [copied from inverse property 'part of continuant at all times that whole exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times' + (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001] + + has continuant part at all times + + + + + b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + + + + + + (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001] + + + + + + + + + + + + c-has-ppart_at + hasProperContinuantPartAt + b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001 + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has proper continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has proper continuant part@en(x,y,t)'. + + has proper continuant part at all times + + + + + + + + + + has-d_st + hasDispositionAt + a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has disposition at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has disposition@en'(x,y,t) + (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001] + + has disposition at some time + + + + + + + + + + + a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001]) + + + + + + (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001] + + - + + + + has-material-basis_at + hasMaterialBasisAt + the material basis of John’s disposition to cough is the viral infection in John’s upper respiratory tract + the material basis of the disposition to wear unevenly of John’s tires is the worn suspension of his car. + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has material basis at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has material basis@en(x,y,t)'. + b has_material_basis c at t means: b is a disposition & c is a material entity & there is some d bearer_of b at t& c continuant_part_of d at t& d has_disposition b at t because c continuant_part_of d at t. (axiom label in BFO2 Reference: [071-002]) + (forall (x y t) (if (hasMaterialBasisAt x y t) (and (Disposition x) (MaterialEntity y) (exists (z) (and (bearerOfAt z x t) (continuantPartOfAt y z t) (exists (w) (and (Disposition w) (if (hasDisposition z w) (continuantPartOfAt y z t))))))))) // axiom label in BFO2 CLIF: [071-002] + + has material basis at all times + + + + + + + + + + + + + + + + + + b has_material_basis c at t means: b is a disposition & c is a material entity & there is some d bearer_of b at t& c continuant_part_of d at t& d has_disposition b at t because c continuant_part_of d at t. (axiom label in BFO2 Reference: [071-002]) + + + + + + (forall (x y t) (if (hasMaterialBasisAt x y t) (and (Disposition x) (MaterialEntity y) (exists (z) (and (bearerOfAt z x t) (continuantPartOfAt y z t) (exists (w) (and (Disposition w) (if (hasDisposition z w) (continuantPartOfAt y z t))))))))) // axiom label in BFO2 CLIF: [071-002] + + + + + + + + + + + + + has-member-part_st + [copied from inverse property 'member part of at some time'] each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles. + [copied from inverse property 'member part of at some time'] each tree in a forest is a member_part of the forest + [copied from inverse property 'member part of at some time'] b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n &gt; 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004]) + [copied from inverse property 'member part of at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'member part of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'member part of@en'(x,y,t) + [copied from inverse property 'member part of at some time'] BFO2 Reference: object + [copied from inverse property 'member part of at some time'] BFO2 Reference: object aggregate + + has member part at some time + + + + + + + + + + + + + - + + + + + + o-has-part + hasOccurrentPart + [copied from inverse property 'part of occurrent'] Mary’s 5th birthday occurrent_part_of Mary’s life + [copied from inverse property 'part of occurrent'] The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football. + [copied from inverse property 'part of occurrent'] the first set of the tennis match occurrent_part_of the tennis match. + b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) + [copied from inverse property 'part of occurrent'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + [copied from inverse property 'part of occurrent'] BFO2 Reference: occurrent + [copied from inverse property 'part of occurrent'] b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002]) + (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001] + + has occurrent part + + + + + + + + + + + + + + + + + + + + + + + b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) + + + + + + (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001] + + + + + + + + + + + + + + o-has-ppart + hasProperOccurrentPart + [copied from inverse property 'proper part of occurrent'] b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001]) + b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001 + + has proper occurrent part + + + + + + + + + + + + + + + + + + + + + + + + + + + + + has-profile + + has profile + + + + + + + + + + + + + + + + + + + + + + + + + has-t-part + [copied from inverse property 'temporal part of'] the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life + [copied from inverse property 'temporal part of'] the process boundary which separates the 3rd and 4th years of your life. + [copied from inverse property 'temporal part of'] your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating + [copied from inverse property 'temporal part of'] b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001]) + [copied from inverse property 'temporal part of'] b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) + + has temporal part + + + + + + + + + + + + + + + + + + + + + + + + + + + + r-location-of_st + [copied from inverse property 'occupies spatial region at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t) + [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: independent continuant + [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: spatial region + [copied from inverse property 'occupies spatial region at some time'] b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002]) + + has spatial occupant at some time + + + + + + + + + + + + + + + + + + + + + + + has-location_st + [copied from inverse property 'located in at some time'] Mary located_in Salzburg + [copied from inverse property 'located in at some time'] the Empire State Building located_in New York. + [copied from inverse property 'located in at some time'] this portion of cocaine located_in this portion of blood + [copied from inverse property 'located in at some time'] this stem cell located_in this portion of bone marrow + [copied from inverse property 'located in at some time'] your arm located_in your body + [copied from inverse property 'located in at some time'] b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001]) + [copied from inverse property 'located in at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t) + [copied from inverse property 'located in at some time'] BFO2 Reference: independent continuant + + has location at some time + + + + + + + + + + + + + + + + + + + + + + + has-s-dep_st + [copied from inverse property 'specifically depends on at some time'] A pain s-depends_on the organism that is experiencing the pain + [copied from inverse property 'specifically depends on at some time'] a gait s-depends_on the walking object. (All at some specific time.) + [copied from inverse property 'specifically depends on at some time'] a shape s-depends_on the shaped object + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat + [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs + [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of buying and the associated process of selling + [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas + [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces + [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball + [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: handwave on a hand + [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45 + [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45 + [copied from inverse property 'specifically depends on at some time'] the two-sided reciprocal s-dependence of the roles of husband and wife [20 + [copied from inverse property 'specifically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t) + [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28 + [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20 + [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place. + [copied from inverse property 'specifically depends on at some time'] BFO2 Reference: specifically dependent continuant\; process; process boundary + [copied from inverse property 'specifically depends on at some time'] To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64 + + has specific dependent at some time + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + occupied-by + [copied from inverse property 'occupies spatiotemporal region'] BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region. + [copied from inverse property 'occupies spatiotemporal region'] p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003]) + + has spatiotemporal occupant + + + + + + + + + + + + + + + + + + + + + + material-basis-of_st + + material basis of at some time + + + + + + + + + + + + + + + + + + + + + + + + member-part-of_st + memberPartOfAt + each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles. + each tree in a forest is a member_part of the forest + b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n &gt; 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'member part of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'member part of@en'(x,y,t) + BFO2 Reference: object + BFO2 Reference: object aggregate + if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001]) + (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001] + + member part of at some time + + + + + + + + + + + + + + + + + b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n &gt; 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004]) + + + + + + if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001]) + + + + + + (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001] + + + + + + + + + + + occupies + occupiesSpatiotemporalRegion + BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region. + p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003]) + + occupies spatiotemporal region + + + + + + + + + + + + + + + + + p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003]) + + - + + + + + o-part-of + occurrentPartOf + Mary’s 5th birthday occurrent_part_of Mary’s life + The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football. + the first set of the tennis match occurrent_part_of the tennis match. + [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) + BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + BFO2 Reference: occurrent + b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002]) + occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001]) + occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002]) + occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001]) + occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001]) + occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001]) + (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001] + (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001] + (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001] + (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001] + (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002] + + part of occurrent + + + + + + + + + + + + + + + + + + + + + + + b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002]) + + + + + + occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001]) + + + + + + occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002]) + + + + + + occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001]) + + + + + + occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001]) + + + + + + occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001]) + + + + + + (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001] + + + + + + (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001] + + + + + + (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001] + + + + + + (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001] + + + + + + (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002] + + + + + + + + + + + profile-of + processProfileOf + + process profile of + + + + + + + + + + + + + + + + + + + + + + + + + + t-ppart-of + properTemporalPartOf + + proper temporal part of + + + + + + + + + + + + + + + + + + + + + + + + + + + + + c-ppart-of_at + properContinuantPartOfAt + b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'proper part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'proper part of continuant@en(x,y,t)'. + (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001] + + proper part of continuant at all times + + + + + b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001]) + + + + + + (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001] + + + + + + + + + + + + + o-ppart-of + properOccurrentPartOf + [copied from inverse property 'has proper occurrent part'] b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001 + b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001]) + (iff (properOccurrentPartOf a b) (and (occurrentPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [005-001] + + proper part of occurrent + + + + + + + + + + + + + + + + + + + + + + + b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001]) + + + + + + (iff (properOccurrentPartOf a b) (and (occurrentPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [005-001] + + + + + + + + + + + + + t-part-of + temporalPartOf + the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life + the process boundary which separates the 3rd and 4th years of your life. + your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating + b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001]) + b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) + if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002]) + (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002] + (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001] + (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003] + + temporal part of + + + + + + + + + + + + + + + + + + + + + + + b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001]) + + + + + + b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) + + + + + + if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002]) + + + + + + (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002] + + + + + + (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001] + + + + + + (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003] + + + + + + + + + + + + st-projects-onto-s_st + + projects onto spatial region at some time + + + + + + + + + + + + + + + + + + + + + + s-projection-of-st_st + + spatial projection of spatiotemporal at some time + + + + + + + + + + + + + + + + + + + + + + + + st-projects-onto-t + + projects onto temporal region + + + + + + + + + + + + + + + + + + + + + + + t-projection-of-st + + temporal projection of spatiotemporal + + + + + + + + + + + + + + + + + + + + + + + + spans + occupiesTemporalRegion + p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001]) + + occupies temporal region + + + + + + + + + + + + + + + + + p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001]) + + + + + + + + + + + + span-of + spanOf + [copied from inverse property 'occupies temporal region'] p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001]) + + has temporal occupant + + + + + + + + + + + + + + + + + + + + + + during-which-exists + [copied from inverse property 'exists at'] BFO2 Reference: entity + [copied from inverse property 'exists at'] BFO2 Reference: temporal region + [copied from inverse property 'exists at'] b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002]) + + during which exists + + + + + + + + + + + + + + + + + + + + + + + bearer-of_at + bearerOfAt + b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'bearer of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'bearer of@en(x,y,t)'. + BFO2 Reference: independent continuant that is not a spatial region + BFO2 Reference: specifically dependent continuant + (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004] + + bearer of at all times + + + + + + + + + + + + + + + + + + + + + + + + + b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) + + + + + + (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004] + + + + + + + + + + + has-q_at + + has quality at all times + + + + + + + + + + + + + + + + has-f_at + hasFunctionAt + a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has function at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has function@en(x,y,t)'. + (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001] + + has function at all times + + + + + + + + + + + a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001]) + + + + + + (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001] + + + + + + + + + + + has-r_at + hasRoleAt + a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has role at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has role@en(x,y,t)'. + (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001] + + has role at all times + + + + + + + + + + + a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001]) + + + + + + (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001] + + + + + + + + + + + has-d_at + hasDispositionAt + a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has disposition at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has disposition@en(x,y,t)'. + (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001] + + has disposition at all times + + + + + + + + + + + a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001]) + + + + + + (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001] + + + + + + + + + + + + material-basis-of_at + + material basis of at all times + + + + + + + + + + + + + + + + + + + + + concretizes_at + concretizesAt + You may concretize a piece of software by installing it in your computer + You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head. + you may concretize a poem as a pattern of memory traces in your head + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'concretizes at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'concretizes@en(x,y,t)'. + b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002]) + if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001]) + (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002] + (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001] + + concretizes at all times + + + + + b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002]) + + + + + + if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001]) + + + + + + (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002] + + + + + + (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001] + + + + + + + + + + concretized-by_at + + concretized by at all times + + + + + + + + + participates-in_at + participatesInAt + + participates in at all times + - + + + + + + + + + + + + + + has-participant_at + hasParticipantAt + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has participant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has participant@en(x,y,t)'. + BFO 2 Reference: Spatial regions do not participate in processes. + BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant + BFO2 Reference: process + has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003]) + if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003]) + if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003]) + if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001]) + if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001]) + if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001]) + (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003] + (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003] + (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001] + (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001] + (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001] + + has participant at all times + + + + + has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003]) + + + + + + if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003]) + + + + + + if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003]) + + + + + + if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001]) + + + + + + if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001]) + + + + + + if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001]) + + + + + + (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003] + + + + + + (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001] + + + + + + (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001] + + + + + + + + + + has-s-dep_at + + has specific dependent at all times + + + + + + + + + + s-depends-on_st + specificallyDependsOn + A pain s-depends_on the organism that is experiencing the pain + a gait s-depends_on the walking object. (All at some specific time.) + a shape s-depends_on the shaped object + one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head + one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism + one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell + one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant + one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question + one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command + one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat + one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs + reciprocal s-dependence between occurrents: a process of buying and the associated process of selling + reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas + reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces + the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball + the one-sided dependence of an occurrent on an independent continuant: handwave on a hand + the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45 + the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45 + the two-sided reciprocal s-dependence of the roles of husband and wife [20 + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t) + BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28 + BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20 + BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place. + BFO2 Reference: specifically dependent continuant\; process; process boundary + To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64 + If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001]) + If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001]) + If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002]) + an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002]) + if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002]) + (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002] + (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002] + (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001] + (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002] + (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001] + + specifically depends on at some time + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001]) + + + + + + If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001]) + + + + + + If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002]) + + + + + + an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002]) + + + + + + if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002]) + + + + + + (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002] + + + + + + (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002] + + + + + + (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001] + + + + + + (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002] + + + + + + (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001] + + + + + + + + + + + has-location_at + + has location at all times + + + + + + + + + + located-in_st + locatedInAt + Mary located_in Salzburg + the Empire State Building located_in New York. + this portion of cocaine located_in this portion of blood + this stem cell located_in this portion of bone marrow + your arm located_in your body + b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t) + BFO2 Reference: independent continuant + Located_in is transitive. (axiom label in BFO2 Reference: [046-001]) + for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001]) + for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001]) + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001] + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001] + (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001] + (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001] + + located in at some time + + + + + + + + + + + + + + + + + b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001]) + + + + + + Located_in is transitive. (axiom label in BFO2 Reference: [046-001]) + + + + + + for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001]) + + + + + + for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001]) + + + + + + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001] + + + + + + (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001] + + + + + + (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001] + + + + + + (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001] + + - + + + + + has-member-part_at + + has member part at all times + + + + + + + + + + + member-part-of_at + memberPartOfAt + each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles. + each tree in a forest is a member_part of the forest + b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n &gt; 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'member part of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'member part of@en(x,y,t)'. + BFO2 Reference: object + BFO2 Reference: object aggregate + if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001]) + (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001] + + member part of at all times + + + + + b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n &gt; 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004]) + + + + + + if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001]) + + + + + + (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001] + + + + + + + + + + + + + c-has-ppart_st + hasProperContinuantPartAt + [copied from inverse property 'proper part of continuant at some time'] b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001]) + b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001 + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has proper continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has proper continuant part@en'(x,y,t) + [copied from inverse property 'proper part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'proper part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'proper part of continuant@en'(x,y,t) + + has proper continuant part at some time + + + + + + + + + + + + + + + + + + + + + + + c-ppart-of_st + properContinuantPartOfAt + [copied from inverse property 'has proper continuant part at some time'] b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001 + b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'proper part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'proper part of continuant@en'(x,y,t) + [copied from inverse property 'has proper continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has proper continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has proper continuant part@en'(x,y,t) + (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001] + + proper part of continuant at some time + + + + + + + + + + + + + + + + + b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001]) + + + + + + (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001] + + + + + + + + + + + + c-part-of_st + continuantPartOfAt + Mary’s arm continuant_part_of Mary in the time of her life prior to her operation + the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists. + [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t) + BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + BFO2 Reference: continuant + BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region. + [copied from inverse property 'has continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t) + b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001]) + continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002]) + continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001]) + continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001]) + continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001]) + if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002]) + (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002] + (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002] + (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001] + (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001] + (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001] + (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001] + (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001] + + part of continuant at some time + + + + + + + + + + + + + + + + + BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + + + + + + b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + + + + + + continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001]) + + + + + + continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002]) + + + + + + continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001]) + + + + + + continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001]) + + + + + + continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001]) + + + + + + if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002]) + + + + + + (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001] + + + + + + (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001] + + + + + + (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001] + + + + + + (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001] + + + + + + + + + + + + c-part-of_at + continuantPartOfAt + Mary’s arm continuant_part_of Mary in the time of her life prior to her operation + the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists. + [copied from inverse property 'has continuant part at all times that part exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'. + BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + BFO2 Reference: continuant + BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region. + [copied from inverse property 'has continuant part at all times that part exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times' + b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001]) + continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002]) + continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001]) + continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001]) + continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001]) + if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002]) + (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002] + (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002] + (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001] + (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001] + (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001] + (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001] + (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001] + + part of continuant at all times + + + + + BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + + + + + + b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + + + + + + + continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001]) + + + + + + continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002]) + + + + + + continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001]) + + + + + + continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001]) + + + + + + continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001]) + + + + + + if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002]) + + + + + + (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001] + + + + + + (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001] + + + + + + (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001] + + + + + + (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001] + + + + + + (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001] + + + + + + + + + + + c-has-part_st + hasContinuantPartAt + [copied from inverse property 'part of continuant at some time'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation + [copied from inverse property 'part of continuant at some time'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists. + b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t) + [copied from inverse property 'part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t) + [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuant + [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region. + [copied from inverse property 'part of continuant at some time'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001] + + has continuant part at some time + + + + + + + + + + + + + + + + + b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + + + + + + (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001] + + + + + + + + + + + + + + has-t-ppart + + has proper temporal part + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + history-of + historyOf + [copied from inverse property 'has history'] b has_history c iff c history_of b [XXX-001 + b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001 + + history of + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + has-history + hasHistory + b has_history c iff c history_of b [XXX-001 + [copied from inverse property 'history of'] b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001 + + has history + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + c-part-of-object_at + [copied from inverse property 'has continuant part at all times'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) + forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t) + This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times' + [copied from inverse property 'has continuant part at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'. + + part of continuant at all times that whole exists + + + + + + + + + + + + + + + + + + + + + + + + forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t) + + + + + + This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times' + + + + + + + + + + + + + c-has-part-object_at + [copied from inverse property 'part of continuant at all times'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation + [copied from inverse property 'part of continuant at all times'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists. + forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) + This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times' + [copied from inverse property 'part of continuant at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'. + [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001]) + [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion. + [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuant + [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region. + [copied from inverse property 'part of continuant at all times'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001]) + + has continuant part at all times that part exists + + + + + + + + + + + + + + + + + + + + + + + forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) + + + + + + + This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times' + + @@ -174,27 +3932,2462 @@ + + + + + entity + Entity + Julius Caesar + Verdi’s Requiem + the Second World War + your body mass index + BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 + Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf + An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) + + entity + + + + + + + + + + + + + + + Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf + + per discussion with Barry Smith + + + + + + An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) + + + + + + + + + + + continuant + Continuant + BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 + Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants + A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) + if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) + if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) + if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) + (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] + (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] + (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] + (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] + + continuant + + + + + Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants + + + + + + A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) + + + + + + if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) + + + + + + if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) + + + + + + if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) + + + + + + (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] + + + + + + (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] + + + + + + (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] + + + + + + (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] + + + + + + + + + + occurrent + Occurrent + BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region + BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. + Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. + Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. + An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) + Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) + b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) + (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] + (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] + + occurrent + + + + + Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. + + per discussion with Barry Smith + + + + + Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. + + + + + + An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) + + + + + + Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) + + + + + + b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) + + + + + + (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] + + + + + + (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] + + + + + + + + + + + + + ic + IndependentContinuant + a chair + a heart + a leg + a molecule + a spatial region + an atom + an orchestra. + an organism + the bottom right portion of a human torso + the interior of your mouth + b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) + For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) + For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) + (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] + (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] + (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] + + independent continuant + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) + + + + + + For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) + + + + + + For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) + + + + + + (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] + + + + + + (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] + + + + + + (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] + + + + + + + + + + + + + + + + s-region + SpatialRegion + BFO 2 Reference: Spatial regions do not participate in processes. + Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. + A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) + All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) + (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] + (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] + + spatial region + + + + + + + + + + + + + + + + + + + + true + + + + true + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. + + per discussion with Barry Smith + + + + + A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) + + + + + + All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) + + + + + + (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] + + + + + + (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] + + + + + + + + + + + + + + t-region + TemporalRegion + Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional + A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) + All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) + Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) + (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] + (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] + (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] + + temporal region + + + + + + + + + + + + true + + + + true + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional + + per discussion with Barry Smith + + + + + A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) + + + + + + All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) + + + + + + Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) + + + + + + (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] + + + + + + (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] + + + + + + (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] + + + + + + + + + + + + 2d-s-region + TwoDimensionalSpatialRegion + an infinitely thin plane in space. + the surface of a sphere-shaped part of space + A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) + (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] + + two-dimensional spatial region + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) + + + + + + (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] + + + + + + + + + + + + + + + + + + + + + st-region + SpatiotemporalRegion + the spatiotemporal region occupied by a human life + the spatiotemporal region occupied by a process of cellular meiosis. + the spatiotemporal region occupied by the development of a cancer tumor + A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) + All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) + Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) + Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) + Every spatiotemporal region occupies_spatiotemporal_region itself. + Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) + (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] + (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] + (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] + (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] + (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] + + spatiotemporal region + + + + + + + + + + + + + + + + true + + + + true + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) + + + + + + All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) + + + + + + Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) + + + + + + Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) + + + + + + Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) + + + + + + (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] + + + + + + (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] + + + + + + (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] + + + + + + (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] + + + + + + (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] + + + + + - + + + + + + + + + + + process + Process + a process of cell-division, \ a beating of the heart + a process of meiosis + a process of sleeping + the course of a disease + the flight of a bird + the life of an organism + your process of aging. + p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) + BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) + (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] + + process + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) + + + + + + (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] + + - + + + + + + disposition + Disposition + an atom of element X has the disposition to decay to an atom of element Y + certain people have a predisposition to colon cancer + children are innately disposed to categorize objects in certain ways. + the cell wall is disposed to filter chemicals in endocytosis and exocytosis + BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. + b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) + If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) + (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] + (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] + + disposition + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) + + + + + + If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) + + + + + + (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] + + + + + + (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] + + + + + + + + + + + + + realizable + RealizableEntity + the disposition of this piece of metal to conduct electricity. + the disposition of your blood to coagulate + the function of your reproductive organs + the role of being a doctor + the role of this boundary to delineate where Utah and Colorado meet + To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) + All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) + (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] + (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] + + realizable entity + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) + + + + + + All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) + + + + + + (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] + + + + + + (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] + + + + + + + + + + + + 0d-s-region + ZeroDimensionalSpatialRegion + A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) + (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] + + zero-dimensional spatial region + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) + + + + + + (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] + + - + + + + + quality + Quality + the ambient temperature of this portion of air + the color of a tomato + the length of the circumference of your waist + the mass of this piece of gold. + the shape of your nose + the shape of your nostril + a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) + If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) + (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] + (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] + + quality + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) + + + + + + If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) + + + + + + (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] + + + + + + (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] + + + + + + + + + + + + + sdc + SpecificallyDependentContinuant + Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key + of one-sided specifically dependent continuants: the mass of this tomato + of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. + the disposition of this fish to decay + the function of this heart: to pump blood + the mutual dependence of proton donors and acceptors in chemical reactions [79 + the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction + the pink color of a medium rare piece of grilled filet mignon at its center + the role of being a doctor + the shape of this hole. + the smell of this portion of mozzarella + b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) + b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) + Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. + (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] + (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] + + specifically dependent continuant + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) + + + + + + b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) + + + + + + Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. + + per discussion with Barry Smith + + + + + (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] + + + + + + (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] + + + + + + + + + + + + role + Role + John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. + the priest role + the role of a boundary to demarcate two neighboring administrative territories + the role of a building in serving as a military target + the role of a stone in marking a property boundary + the role of subject in a clinical trial + the student role + BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. + b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) + (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] + + role + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) + + + + + + (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] + + + + + + + + + + fiat-object + FiatObjectPart + or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29 + the FMA:regional parts of an intact human body. + the Western hemisphere of the Earth + the division of the brain into regions + the division of the planet into hemispheres + the dorsal and ventral surfaces of the body + the upper and lower lobes of the left lung + BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions + b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) + (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] + + fiat object + + + + + b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) + + + + + + (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] + + + + + + + + + + + + 1d-s-region + OneDimensionalSpatialRegion + an edge of a cube-shaped portion of space. + A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) + (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] + + one-dimensional spatial region + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) + + + + + + (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] + + + + + + + + + + object-aggregate + ObjectAggregate + a collection of cells in a blood biobank. + a swarm of bees is an aggregate of members who are linked together through natural bonds + a symphony orchestra + an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team) + defined by fiat: the aggregate of members of an organization + defined through physical attachment: the aggregate of atoms in a lump of granite + defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container + defined via attributive delimitations such as: the patients in this hospital + the aggregate of bearings in a constant velocity axle joint + the aggregate of blood cells in your body + the nitrogen atoms in the atmosphere + the restaurants in Palo Alto + your collection of Meissen ceramic plates. + An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects + BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee). + ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. + b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) + (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] + + object aggregate + + + + + An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects + + + + + + An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects + + + + + + ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. + + + + + + b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) + + + + + + (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] + + + + + + + + + + 3d-s-region + ThreeDimensionalSpatialRegion + a cube-shaped region of space + a sphere-shaped region of space, + A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) + (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] + + three-dimensional spatial region + + + + + A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) + + + + + + (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] + + + + + + + + + + site + Site + Manhattan Canyon) + a hole in the interior of a portion of cheese + a rabbit hole + an air traffic control region defined in the airspace above an airport + the Grand Canyon + the Piazza San Marco + the cockpit of an aircraft + the hold of a ship + the interior of a kangaroo pouch + the interior of the trunk of your car + the interior of your bedroom + the interior of your office + the interior of your refrigerator + the lumen of your gut + your left nostril (a fiat part – the opening – of your left nasal cavity) + b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) + (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] + + site + + + + + b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) + + + + + + (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] + + + + + + + + + + object + Object + atom + cell + cells and organisms + engineered artifacts + grain of sand + molecule + organelle + organism + planet + solid portions of matter + star + BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting. + BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below). + BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47 + BFO 2 Reference: an object is a maximal causally unified material entity + BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74 + b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) + + object + + + + + b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) + + + + + + + + + + + + + gdc + GenericallyDependentContinuant + The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. + the pdf file on your laptop, the pdf file that is a copy thereof on my laptop + the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. + b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) + (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] + + generically dependent continuant + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) + + + + + + (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] + + + + + + + + + + function + Function + the function of a hammer to drive in nails + the function of a heart pacemaker to regulate the beating of a heart through electricity + the function of amylase in saliva to break down starch into sugar + BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc. + A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) + (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] + + function + + + + + A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) + + + + + + (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] + + + + + + + + + + + + + + p-boundary + ProcessBoundary + the boundary between the 2nd and 3rd year of your life. + p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) + Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) + (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] + (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] + + process boundary + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) + + + + + + Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) + + + + + + (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] + + + + + + (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] + + + + + + + + + + + 1d-t-region + OneDimensionalTemporalRegion + the temporal region during which a process occurs. + BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks). + A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) + (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] + + one-dimensional temporal region + + + + + A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) + + + + + + (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] + + - + + + + + + + + + + + + + + + + + + + material + MaterialEntity + a flame + a forest fire + a human being + a hurricane + a photon + a puff of smoke + a sea wave + a tornado + an aggregate of human beings. + an energy wave + an epidemic + the undetached arm of a human being + BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 + BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. + BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. + A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) + Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) + every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) + (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] + (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] + (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] + + material entity + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) + + + + + + Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) + + + + + + every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) + + + + + + (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] + + + + + + (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] + + + + + + (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] + + + + + + + + + + + + + + + cf-boundary + ContinuantFiatBoundary + b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) + BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions. + BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29 + Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. + Every continuant fiat boundary is located at some spatial region at every time at which it exists + (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] + + continuant fiat boundary + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) + + + + + + Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. + + + + + + (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] + + + + + + + + + + + + + + immaterial + ImmaterialEntity + BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10 + + immaterial entity + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 1d-cf-boundary + OneDimensionalContinuantFiatBoundary + The Equator + all geopolitical boundaries + all lines of latitude and longitude + the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin. + the median sulcus of your tongue + a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) + (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] + + one-dimensional continuant fiat boundary + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) + + + + + + (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] + + + + + + + + + + + + + process-profile + ProcessProfile + On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels + One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance. + The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on. + b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) + b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) + (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] + (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] + + process profile + + + + + + + + + + + + + + + + + + + + + + + + + b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) + + + + + + b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) + + + + + + (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] + + + + + + (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] + + + + + + + + + + + r-quality + RelationalQuality + John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. + a marriage bond, an instance of love, an obligation between one person and another. + b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) + (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] + + relational quality + + + + + + + 2 + + + + + + + + + + + + + + b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) + + + + + + (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] + + + + + + + + + + 2d-cf-boundary + TwoDimensionalContinuantFiatBoundary + a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) + (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] + + two-dimensional continuant fiat boundary + + + + + a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) + + + + + + (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] + + + + + + + + + + + + 0d-cf-boundary + ZeroDimensionalContinuantFiatBoundary + the geographic North Pole + the point of origin of some spatial coordinate system. + the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet + zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. + a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) + (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] + + zero-dimensional continuant fiat boundary + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. + + requested by Melanie Courtot + + + + + + a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) + + + + + + (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] + + + + + + + + + + 0d-t-region + ZeroDimensionalTemporalRegion + a temporal region that is occupied by a process boundary + right now + the moment at which a child is born + the moment at which a finger is detached in an industrial accident + the moment of death. + temporal instant. + A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) + (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] + + zero-dimensional temporal region + + + + + A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) + + + + + + (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] + + + + + + + + + + + + + + + + + + + + + + + + + + history + History + A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001]) + + history + + + + + A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001]) + + @@ -5577,6 +11770,10 @@ + + disease_ontology + DOID:0000405 + vascular tissue disease @@ -5612,6 +11809,23 @@ A cardiomyopathy characterized by adipose and fibrosis infiltration in the right ventricular myocardium. It is caused by genetic defects of desmosomes (which are parts of the myocardium) and may result in arrhythmia. + + MSH:D019571 + OMIM:107970 + OMIM:600996 + OMIM:604400 + OMIM:607450 + OMIM:609040 + OMIM:610193 + OMIM:610476 + OMIM:611528 + ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY 1 + ARVD + arrhythmogenic right ventricular dysplasia/cardiomyopathy + disease_ontology + DOID:0050431 + OMIM mapping confirmed by DO. [SN]. + arrhythmogenic right ventricular dysplasia @@ -5643,6 +11857,21 @@ A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death by ventricular tachyarrhytmia. + A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. + + MSH:D053840 + OMIM:601144 + OMIM:611777 + OMIM:611875 + OMIM:611876 + OMIM:612838 + OMIM:613119 + OMIM:613120 + OMIM:613123 + disease_ontology + DOID:0050451 + OMIM mapping confirmed by DO. [SN]. + Brugada syndrome @@ -5651,6 +11880,13 @@ + + OMIM:208000 + IDIOPATHIC INFANTILE ARTERIAL CALCIFICATION + disease_ontology + DOID:0050644 + OMIM mapping confirmed by DO. [SN]. + generalized arterial calcification of infancy @@ -5659,6 +11895,12 @@ + + OMIM:208050 + disease_ontology + DOID:0050645 + OMIM mapping confirmed by DO. [SN]. + arterial tortuosity syndrome @@ -5674,6 +11916,14 @@ An atrial fibrillation disease that has a genetic origin. + A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has_material_basis_in autosomal dominant inheritance of the familial atrial fibrillation (ATFB) genes. + + OMIM:607554 + OMIM:611493 + OMIM:612201 + OMIM:612240 + disease_ontology + DOID:0050650 familial atrial fibrillation @@ -5733,6 +11983,13 @@ Disease of the myocardium associated with cardiac dysfunction. (Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies) DOID label "cardiomyopathy" was changed. + A heart disease that is characterized by deterioration of the funciton of the heart muscle. + + lschriml + 2012-01-03T02:54:11Z + disease_ontology + DOID:0050700 + cardiomyopathy (1995 definition) @@ -5740,6 +11997,7 @@ + @@ -5757,6 +12015,11 @@ An endocarditis caused by infection. + A heart disease involving inflammation of the endocardium (inner layer of the heart) caused by bacterial infection. + + disease_ontology + DOID:0060000 + infective endocarditis @@ -5764,6 +12027,7 @@ + @@ -5796,13 +12060,40 @@ + An non-infective endocarditis that results in the deposition of small sterile vegetations on valve leaflets. DOID label 'marantic endocarditis' was changed in CVDO (non-bacterial thrombotic endocarditis is a more common name). + + lschriml + 2011-04-13T03:14:26Z marantic endocarditis + disease_ontology + DOID:0060068 non-bacterial thrombotic endocarditis + + + + + + ICD9CM:434 + ICD9CM:434.9 + SNOMEDCT_2010_1_31:155400001 + SNOMEDCT_2010_1_31:155403004 + SNOMEDCT_2010_1_31:195188006 + SNOMEDCT_2010_1_31:20059004 + SNOMEDCT_2010_1_31:266255008 + SNOMEDCT_2010_1_31:286956007 + UMLS_CUI:C0028790 + disease_ontology + DOID:10127 + cerebral artery occlusion + + + + @@ -5823,6 +12114,29 @@ + + ICD9CM:459.81 + MSH:D014689 + SNOMEDCT_2010_1_31:20696009 + UMLS_CUI:C0042485 + peripheral venous insufficiency + disease_ontology + DOID:10128 + venous insufficiency + + + + + + + + + + SNOMEDCT_2010_1_31:65443008 + UMLS_CUI:C0155593 + disease_ontology + DOID:10177 + malignant hypertensive renal disease @@ -5830,6 +12144,7 @@ + @@ -5856,6 +12171,17 @@ + + ICD9CM:440.0 + SNOMEDCT_2010_1_31:155415000 + SNOMEDCT_2010_1_31:195252007 + SNOMEDCT_2010_1_31:81817003 + UMLS_CUI:C0155733 + Aortic atherosclerosis + Atherosclerosis of aorta (disorder) + disease_ontology + DOID:10230 + aortic atherosclerosis @@ -5864,6 +12190,28 @@ + + ICD9CM:115.93 + SNOMEDCT_2010_1_31:187059008 + UMLS_CUI:C0153279 + Histoplasmosis with pericarditis (disorder) + disease_ontology + DOID:10234 + histoplasmosis pericarditis + + + + + + + + + + ICD9CM:410.7 + UMLS_CUI:C0155655 + disease_ontology + DOID:10266 + subendocardial infarction acute myocardial infarction @@ -5899,6 +12247,19 @@ DOID label changed to 'left anterior fascicular block (disease)' for symmetry reasons with 'left posterior fascicular block (disease)' + + ICD9CM:426.2 + SNOMEDCT_2010_1_31:195044001 + SNOMEDCT_2010_1_31:195045000 + SNOMEDCT_2010_1_31:266245009 + SNOMEDCT_2010_1_31:4973001 + UMLS_CUI:C0155702 + Left bundle branch [block] or [hemiblock] + Left bundle branch hemiblock (disorder) + Left bundle branch hemiblock NOS (disorder) + left bundle branch hemiblock + disease_ontology + DOID:10272 left anterior fascicular block (disease) @@ -5937,6 +12298,46 @@ A disease affecting the conducting tissue of the heart. + A heart disease that involves the heart's electrical conduction system. + + ICD9CM:426.6 + SNOMEDCT_2010_1_31:195053008 + SNOMEDCT_2010_1_31:195056000 + UMLS_CUI:C0029630 + disease_ontology + DOID:10273 + heart conduction disease + + + + + + + + + + ICD9CM:443.0 + MSH:D011928 + NCI:C34972 + OMIM:179600 + SNOMEDCT_2010_1_31:123266007 + SNOMEDCT_2010_1_31:155429004 + SNOMEDCT_2010_1_31:195294005 + SNOMEDCT_2010_1_31:195295006 + SNOMEDCT_2010_1_31:195297003 + SNOMEDCT_2010_1_31:22954002 + SNOMEDCT_2010_1_31:266319002 + UMLS_CUI:C0034734 + Raynaud's disease + Raynaud's disease (disorder) + Raynaud's syndrome + Raynaud's syndrome (disorder) + Raynaud's syndrome (disorder) [Ambiguous] + Raynaud's syndrome NOS (disorder) + disease_ontology + DOID:10300 + OMIM mapping confirmed by DO. [SN]. + Raynaud disease @@ -5966,6 +12367,19 @@ A disease characterized by an inflammation of the endocardium. + A heart disease involving non-infectious inflammation of the endocardium (inner layer of the heart). + + DOID:14058 + MSH:D004696 + NCI:C34582 + SNOMEDCT_2010_1_31:194935007 + SNOMEDCT_2010_1_31:56819008 + SNOMEDCT_2010_1_31:91357005 + UMLS_CUI:C0014118 + UMLS_CUI:C0375268 + disease_ontology + DOID:10314 + endocarditis @@ -5995,6 +12409,35 @@ DOID label 'anomalous atrioventricular excitation' was changed. + + ICD9CM:426.7 + SNOMEDCT_2010_1_31:155360000 + SNOMEDCT_2010_1_31:17869006 + SNOMEDCT_2010_1_31:195057009 + SNOMEDCT_2010_1_31:195061003 + SNOMEDCT_2010_1_31:266304003 + UMLS_CUI:C0392470 + Anomalous A-V excitation + disease_ontology + DOID:10392 + anomalous atrioventricular excitation (disease) + + + + + + + + + + ICD9CM:411.0 + SNOMEDCT_2010_1_31:66189004 + UMLS_CUI:C0152107 + Postmyocardial infarction syndrome + Postmyocardial infarction syndrome (disorder) + disease_ontology + DOID:10507 + Dressler's syndrome @@ -6003,6 +12446,30 @@ + + DOID:10555 + DOID:12413 + ICD9CM:669.20 + UMLS_CUI:C0157456 + antepartum maternal hypotension syndrome + postpartum maternal hypotension syndrome + disease_ontology + DOID:10556 + supine hypotensive syndrome + + + + + + + + + + ICD9CM:642.40 + UMLS_CUI:C0156664 + disease_ontology + DOID:10590 + mild pre-eclampsia @@ -6011,6 +12478,155 @@ + + DOID:12684 + MSH:D011225 + NCI:C34943 + NCI:C85021 + OMIM:189800 + OMIM:609404 + SNOMEDCT_2010_1_31:15394000 + SNOMEDCT_2010_1_31:156106005 + SNOMEDCT_2010_1_31:156109003 + SNOMEDCT_2010_1_31:156112000 + SNOMEDCT_2010_1_31:198969004 + SNOMEDCT_2010_1_31:198972006 + SNOMEDCT_2010_1_31:198979002 + SNOMEDCT_2010_1_31:199011002 + SNOMEDCT_2010_1_31:237280005 + SNOMEDCT_2010_1_31:267306006 + SNOMEDCT_2010_1_31:267307002 + SNOMEDCT_2010_1_31:288201007 + SNOMEDCT_2010_1_31:30354006 + SNOMEDCT_2010_1_31:308551004 + SNOMEDCT_2010_1_31:398254007 + SNOMEDCT_2010_1_31:46764007 + SNOMEDCT_2010_1_31:48194001 + SNOMEDCT_2010_1_31:6758009 + UMLS_CUI:C0032914 + UMLS_CUI:C0340274 + Gestational hypertension + Gestational hypertension (disorder) + PREECLAMPSIA/ECLAMPSIA + Pre-eclampsia (disorder) + Pre-eclampsia NOS + Pre-eclampsia NOS (disorder) + Pre-eclamptic NOS + Pre-eclamptic toxaemia + Pregnancy associated hypertension + Pregnancy-induced hypertension (disorder) + Proteinuric hypertension of pregnancy + Toxaemia NOS + Toxaemia of pregnancy + Toxemia NOS (disorder) + Toxemia of Pregnancy + Toxemia of pregnancy (disorder) + hypertension induced by pregnancy + hypertension of preg. + hypertension of pregnancy NOS + hypertension of pregnancy NOS (disorder) + preeclampsia + pregnancy toxemia + disease_ontology + DOID:10591 + OMIM mapping confirmed by DO. [SN]. + pre-eclampsia + + + + + + + + + + ICD9CM:708.0 + SNOMEDCT_2010_1_31:156428000 + SNOMEDCT_2010_1_31:201260002 + SNOMEDCT_2010_1_31:40178009 + UMLS_CUI:C0149526 + Allergic urticaria (disorder) + disease_ontology + DOID:10612 + allergic urticaria + + + + + + + + + + ICD9CM:410.30 + UMLS_CUI:C0155640 + disease_ontology + DOID:10648 + acute inferoposterior infarction + + + + + + + + + + ICD9CM:410.20 + UMLS_CUI:C0155636 + disease_ontology + DOID:10649 + acute inferolateral myocardial infarction + + + + + + + + + + ICD9CM:410.0 + SNOMEDCT_2010_1_31:70211005 + UMLS_CUI:C0155627 + disease_ontology + DOID:10651 + acute anterolateral myocardial infarction + + + + + + + + + + MSH:D006977 + NCI:C3121 + SNOMEDCT_2010_1_31:194775007 + SNOMEDCT_2010_1_31:28119000 + UMLS_CUI:C0020544 + disease_ontology + DOID:1073 + renal hypertension + + + + + + + + + + ICD9CM:572.3 + MSH:D006975 + NCI:C3119 + SNOMEDCT_2010_1_31:155821005 + SNOMEDCT_2010_1_31:34742003 + UMLS_CUI:C0020541 + disease_ontology + DOID:10762 + portal hypertension @@ -6035,6 +12651,141 @@ + + ICD9CM:401-405.99 + ICD9CM:997.91 + MSH:D006973 + NCI:C3117 + SNOMEDCT_2010_1_31:155295004 + SNOMEDCT_2010_1_31:155302005 + SNOMEDCT_2010_1_31:194756002 + SNOMEDCT_2010_1_31:194757006 + SNOMEDCT_2010_1_31:194760004 + SNOMEDCT_2010_1_31:194794002 + SNOMEDCT_2010_1_31:195537001 + SNOMEDCT_2010_1_31:266287006 + SNOMEDCT_2010_1_31:38341003 + UMLS_CUI:C0020538 + HTN + High blood pressure (& [essential hypertension]) + hyperpiesia + vascular hypertensive disorder + disease_ontology + hypertensive disease + DOID:10763 + hypertension + + + + + + + + + + ICD9CM:422.91 + SNOMEDCT_2010_1_31:194954007 + SNOMEDCT_2010_1_31:194955008 + SNOMEDCT_2010_1_31:266238009 + SNOMEDCT_2010_1_31:91025000 + UMLS_CUI:C0155689 + Idiopathic myocarditis + Idiopathic myocarditis (disorder) + Idiopathic myocarditis NOS (disorder) + Isolated (Fiedler's) myocarditis + Isolated (Fiedler's) myocarditis (disorder) + disease_ontology + DOID:10778 + fiedler's myocarditis + + + + + + + + + + ICD9CM:422.92 + SNOMEDCT_2010_1_31:194959002 + SNOMEDCT_2010_1_31:64043005 + UMLS_CUI:C0155690 + Septic myocarditis NOS (disorder) + Septic myocarditis, NOS + disease_ontology + DOID:10779 + septic myocarditis + + + + + + + + + + + ICD9CM:401.0 + NCI:C34802 + SNOMEDCT_2010_1_31:1218009 + SNOMEDCT_2010_1_31:78975002 + UMLS_CUI:C0024588 + Accelerated essential hypertension + malignant Essential hypertension + malignant essential hypertension (disorder) + disease_ontology + DOID:10823 + malignant essential hypertension + + + + + + + + + + MSH:D006974 + NCI:C3118 + SNOMEDCT_2010_1_31:155301003 + SNOMEDCT_2010_1_31:286951002 + SNOMEDCT_2010_1_31:70272006 + UMLS_CUI:C0020540 + malignant hypertension + malignant hypertension (disorder) + disease_ontology + DOID:10824 + malignant hypertension + + + + + + + + + + ICD9CM:401 + ICD9CM:401.9 + NCI:C3478 + OMIM:145500 + SNOMEDCT_2010_1_31:155296003 + SNOMEDCT_2010_1_31:194757006 + SNOMEDCT_2010_1_31:194760004 + SNOMEDCT_2010_1_31:266228004 + SNOMEDCT_2010_1_31:59621000 + UMLS_CUI:C0085580 + Essential hypertension + Essential hypertension (disorder) + Essential hypertension NOS + Essential hypertension NOS (disorder) + Unspecified essential hypertension + idiopathic hypertension + primary hypertension + disease_ontology + DOID:10825 + OMIM mapping confirmed by DO. [SN]. + essential hypertension @@ -6043,6 +12794,105 @@ + + ICD9CM:451.81 + SNOMEDCT_2010_1_31:195429006 + UMLS_CUI:C0155772 + Phlebitis and thrombophlebitis of the iliac vein NOS (disorder) + disease_ontology + DOID:10880 + iliac vein thrombophlebitis + + + + + + + + + + ICD9CM:401.1 + NCI:C3656 + SNOMEDCT_2010_1_31:1201005 + SNOMEDCT_2010_1_31:194758001 + UMLS_CUI:C0155583 + benign Essential hypertension + benign essential hypertension (disorder) + disease_ontology + DOID:10913 + benign essential hypertension + + + + + + + + + + MSH:D002532 + NCI:C34458 + SNOMEDCT_2010_1_31:128609009 + SNOMEDCT_2010_1_31:42994005 + UMLS_CUI:C0007766 + intracranial aneurysm + intracranial aneurysm (disorder) + intracranial aneurysm, NOS + disease_ontology + DOID:10941 + intracranial aneurysm + intracranial aneurysm disease + + + + + + + + + + MSH:D020144 + UMLS_CUI:C0751739 + disease_ontology + DOID:10991 + basal ganglia cerebrovascular disease + + + + + + + + + + ICD9CM:405 + ICD9CM:405.9 + NCI:C3657 + SNOMEDCT_2010_1_31:155300002 + SNOMEDCT_2010_1_31:194789002 + SNOMEDCT_2010_1_31:194792003 + SNOMEDCT_2010_1_31:31992008 + UMLS_CUI:C0155616 + disease_ontology + DOID:11130 + secondary hypertension + + + + + + + + + + ICD9CM:441.6 + SNOMEDCT_2010_1_31:195265003 + UMLS_CUI:C1305122 + Thoracoabdominal aortic aneurysm, ruptured (disorder) + disease_ontology + DOID:11138 + ruptured thoracoabdominal aortic aneurysm + ruptured thoracoabdominal aortic aneurysm disease @@ -6051,6 +12901,49 @@ + + DOID:111 + DOID:13536 + DOID:14031 + ICD9CM:456.0 + NCI:C78282 + SNOMEDCT_2010_1_31:17709002 + SNOMEDCT_2010_1_31:195474004 + SNOMEDCT_2010_1_31:195475003 + SNOMEDCT_2010_1_31:195479009 + SNOMEDCT_2010_1_31:195643006 + SNOMEDCT_2010_1_31:236067006 + UMLS_CUI:C0155789 + UMLS_CUI:C0155791 + UMLS_CUI:C0155792 + Bleeding esophageal varices + Bleeding esophageal varices (disorder) + Bleeding oesophageal varices + esophageal varices + esophageal varices in disease classified elsewhere, with bleeding + esophageal varices with bleeding + esophageal varices with bleeding in disease EC (disorder) + esophageal varices without bleeding + esophageal varices without bleeding (disorder) + esophageal varices without mention of bleeding + disease_ontology + DOID:112 + esophageal varix + + + + + + + + + + ICD9CM:433.2 + UMLS_CUI:C0155724 + Occlusion and stenosis of vertebral artery + disease_ontology + DOID:11299 + vertebral artery occlusion @@ -6080,11 +12973,38 @@ DOID label changed for homogeneization reasons. + + ICD9CM:426.12 + NCI:C62018 + SNOMEDCT_2010_1_31:28189009 + UMLS_CUI:C0155700 + Mobitz (type) II atrioventricular block + Mobitz II atrioventricular block + Mobitz type II atrioventricular block + Mobitz type II atrioventricular block (disorder) + disease_ontology + DOID:11312 Mobitz II second degree atrioventricular block (disease) + + + + + + ICD9CM:437.4 + SNOMEDCT_2010_1_31:28366008 + UMLS_CUI:C0007773 + Cerebral arteritis (disorder) + disease_ontology + DOID:11390 + cerebral arteritis + + + + @@ -6118,6 +13038,70 @@ A disease affecting the heart. + A cardiovascular system disease that involves the heart or blood vessels (arteries and veins). + + ICD9CM:429.9 + MSH:D006331 + NCI:C3079 + SNOMEDCT_2010_1_31:155263000 + SNOMEDCT_2010_1_31:194707003 + SNOMEDCT_2010_1_31:195152001 + SNOMEDCT_2010_1_31:266275004 + SNOMEDCT_2010_1_31:266311004 + SNOMEDCT_2010_1_31:56265001 + UMLS_CUI:C0018799 + disease_ontology + DOID:114 + heart disease + + + + + + + + + + + ICD9CM:348.2 + MSH:D011559 + NCI:C85035 + OMIM:243200 + SNOMEDCT_2010_1_31:155052007 + SNOMEDCT_2010_1_31:267701004 + SNOMEDCT_2010_1_31:68267002 + UMLS_CUI:C0033845 + Pseudotumor cerebri + benign intracran. hypt. + benign intracranial hypertension + benign intracranial hypertension (disorder) + idiopathic intracranial hypertension + disease_ontology + DOID:11459 + OMIM mapping confirmed by DO. [SN]. + pseudotumor cerebri + + + + + + + + + + ICD9CM:423.2 + MSH:D010494 + NCI:C78246 + SNOMEDCT_2010_1_31:155340008 + SNOMEDCT_2010_1_31:194969008 + SNOMEDCT_2010_1_31:85598007 + UMLS_CUI:C0031048 + Constrictive pericarditis + Constrictive pericarditis (disorder) + Constrictive pericarditis NOS (disorder) + disease_ontology + DOID:11481 + constrictive pericarditis @@ -6142,6 +13126,17 @@ + A pericardial effusion that results from blood in the pericardial sac. + + ICD9CM:423.0 + MSH:D010490 + SNOMEDCT_2010_1_31:155339006 + SNOMEDCT_2010_1_31:23412002 + UMLS_CUI:C0019064 + Haemopericardium + disease_ontology + DOID:11482 + hemopericardium @@ -6174,6 +13169,21 @@ A disease caused by the presence of fluid in the pericardial cavity (due to pericardial effusion), affecting negatively the heart's pumping function. In CVDO, cardiac tamponade is defined as *being caused* by a pericardial effusion, rather than as *being* a pericardial effusion. + A pericardial effusion in which fluid accumulates in the pericardium (the sac in which the heart is enclosed) and the pericardial spaces fills up faster than the pericardial sac can stretch. + + ICD9CM:423.3 + MSH:D002305 + NCI:C50481 + SNOMEDCT_2010_1_31:155341007 + SNOMEDCT_2010_1_31:194975004 + SNOMEDCT_2010_1_31:266295005 + SNOMEDCT_2010_1_31:35304003 + UMLS_CUI:C0007177 + Rose's tamponade + pericardial tamponade + disease_ontology + DOID:115 + cardiac tamponade @@ -6223,6 +13233,69 @@ A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve. + + DOID:11737 + MSH:D008944 + NCI:C50852 + NCI:C50888 + SNOMEDCT_2010_1_31:194736003 + SNOMEDCT_2010_1_31:194977007 + SNOMEDCT_2010_1_31:48724000 + SNOMEDCT_2010_1_31:59464004 + UMLS_CUI:C0026266 + UMLS_CUI:C0264774 + Mitral valve incompetence + mitral regurgitation + disease_ontology + DOID:11502 + mitral valve insufficiency + + + + + + + + + + ICD9CM:394 + SNOMEDCT_2010_1_31:155276006 + SNOMEDCT_2010_1_31:194724009 + SNOMEDCT_2010_1_31:250998008 + SNOMEDCT_2010_1_31:266278002 + SNOMEDCT_2010_1_31:286947004 + SNOMEDCT_2010_1_31:83898004 + UMLS_CUI:C0264765 + Mitral RH valve dis. + Mitral valve disease + Rheumatic disease of mitral valve (disorder) + Rheumatic mitral valve changes + chronic rheumatic mitral valve (disorder) + disease of mitral valve + disease_ontology + DOID:11505 + rheumatic disease of mitral valve + + + + + + + + + + MSH:D006502 + SNOMEDCT_2010_1_31:195436007 + SNOMEDCT_2010_1_31:38739001 + UMLS_CUI:C0019154 + Budd - Chiari syndrome (hepatic vein thrombosis) + Budd-Chiari syndrome + Budd-Chiari syndrome (disorder) + hepatic vein thrombosis + hepatic vein thrombosis (disorder) + disease_ontology + DOID:11512 + hepatic vein thrombosis @@ -6247,6 +13320,37 @@ + A heart disease that is caused by high blood presure. + + ICD9CM:402 + ICD9CM:402.9 + SNOMEDCT_2010_1_31:155297007 + SNOMEDCT_2010_1_31:194769003 + SNOMEDCT_2010_1_31:194772005 + SNOMEDCT_2010_1_31:64715009 + UMLS_CUI:C0152105 + disease_ontology + DOID:11516 + hypertensive heart disease + + + + + + + + + + ICD9CM:403.1 + ICD9CM:403.10 + SNOMEDCT_2010_1_31:193003 + UMLS_CUI:C0155596 + benign hypertensive renal disease (disorder) + hypertensive renal disease, benign + hypertensive renal disease, benign, without mention of renal failure + disease_ontology + DOID:11520 + benign hypertensive renal disease @@ -6276,6 +13380,44 @@ A disease characterized by an inflammation of a retinal artery. + + ICD9CM:362.18 + MSH:D031300 + SNOMEDCT_2010_1_31:193367006 + SNOMEDCT_2010_1_31:77628002 + UMLS_CUI:C0152026 + Retinal vasculitis + Retinal vasculitis (disorder) + Retinal vasculitis NOS (disorder) + disease_ontology + DOID:11563 + retinal vasculitis + + + + + + + + + + + ICD9CM:587 + MSH:D009400 + SNOMEDCT_2010_1_31:194773000 + SNOMEDCT_2010_1_31:197658002 + SNOMEDCT_2010_1_31:197662008 + SNOMEDCT_2010_1_31:32916005 + UMLS_CUI:C0027719 + Nephrosclerosis (disorder) + nephrosclerosis + renal sclerosis + renal sclerosis NOS (disorder) + renal sclerosis unspecified (disorder) + renal sclerosis, unspecified + disease_ontology + DOID:11664 + nephrosclerosis @@ -6295,6 +13437,15 @@ A thrombosis that occurs in a portal vein. + + ICD9CM:452 + NCI:C78565 + SNOMEDCT_2010_1_31:155455003 + SNOMEDCT_2010_1_31:17920008 + UMLS_CUI:C0155773 + disease_ontology + DOID:11695 + portal vein thrombosis @@ -6303,6 +13454,15 @@ + + MSH:D003925 + NCI:C35610 + UMLS_CUI:C0011875 + Diabetic vascular disorder + diabetic angiopathy + disease_ontology + DOID:11713 + diabetic angiopathy @@ -6331,6 +13491,16 @@ + A heart disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity. + + MSH:D010490 + NCI:C3319 + SNOMEDCT_2010_1_31:373945007 + SNOMEDCT_2010_1_31:70370001 + UMLS_CUI:C0031039 + disease_ontology + DOID:118 + pericardial effusion @@ -6360,6 +13530,39 @@ A coronary heart disease with coronary artery smooth muscle constriction. + + MSH:D003329 + NCI:C34515 + SNOMEDCT_2010_1_31:23687008 + UMLS_CUI:C0010073 + Coronary Vasospasm + Coronary artery spasm (disorder) + disease_ontology + DOID:11840 + coronary artery vasospasm + + + + + + + + + + ICD9CM:746.85 + SNOMEDCT_2010_1_31:204373000 + SNOMEDCT_2010_1_31:204380003 + SNOMEDCT_2010_1_31:28574005 + SNOMEDCT_2010_1_31:361215006 + UMLS_CUI:C0158623 + Congenital anomaly of coronary artery (disorder) + Coronary artery abnormality (disorder) + Coronary artery abnormality [Ambiguous] + Coronary artery anomaly NOS (disorder) + Coronary artery anomaly, congenital + disease_ontology + DOID:11843 + coronary artery anomaly @@ -6379,6 +13582,20 @@ A thrombosis occuring in a coronary artery. + + MSH:D003328 + SNOMEDCT_2010_1_31:155304006 + SNOMEDCT_2010_1_31:194796000 + SNOMEDCT_2010_1_31:266288001 + SNOMEDCT_2010_1_31:398274000 + SNOMEDCT_2010_1_31:66514008 + UMLS_CUI:C0010072 + Coronary artery thrombosis (disorder) + Coronary thrombosis + coronary thrombosis + disease_ontology + DOID:11847 + coronary thrombosis @@ -6409,6 +13626,31 @@ "A heart disease with increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to cause the observed abnormality." (Elliott et al., 2008, European Heart Journal, 29, 270-276) + + ICD9CM:425.1 + MSH:D002312 + NCI:C34449 + OMIM:192600 + SNOMEDCT_2010_1_31:15471000 + SNOMEDCT_2010_1_31:155351008 + SNOMEDCT_2010_1_31:233873004 + SNOMEDCT_2010_1_31:266301006 + SNOMEDCT_2010_1_31:389998005 + SNOMEDCT_2010_1_31:389999002 + SNOMEDCT_2010_1_31:45227007 + UMLS_CUI:C0007194 + Cardiomyopathy, hypertrophic + hyper. obst. cardiomyopathy + hypertrophic cardiomyopathy + hypertrophic cardiomyopathy (disorder) + hypertrophic myocardiopathy + hypertrophic obstructive cardiomyopathy + hypertrophic obstructive cardiomyopathy (disorder) + primary hypertrophic cardiomyopathy (disorder) [Ambiguous] + disease_ontology + DOID:11984 + OMIM mapping confirmed by DO. [LS]. + hypertrophic cardiomyopathy @@ -6417,6 +13659,35 @@ + + ICD9CM:377.41 + MSH:D018917 + SNOMEDCT_2010_1_31:14357004 + UMLS_CUI:C0155305 + Ischemic optic neuropathy + Ischemic optic neuropathy (disorder) + disease_ontology + DOID:12010 + ischemic optic neuropathy + + + + + + + + + + ICD9CM:395.0 + SNOMEDCT_2010_1_31:155282009 + SNOMEDCT_2010_1_31:72011007 + UMLS_CUI:C0155567 + Rheumatic aortic stenosis + Rheumatic aortic stenosis (disorder) + Rheumatic aortic valve stenosis + disease_ontology + DOID:12034 + rheumatic aortic valve stenosis @@ -6441,6 +13712,35 @@ + + ICD9CM:451.11 + SNOMEDCT_2010_1_31:1748006 + SNOMEDCT_2010_1_31:195410000 + UMLS_CUI:C0265066 + Phlebitis and thrombophlebitis of femoral vein (deep) (superficial) + Thrombophlebitis of deep femoral vein (disorder) + Thrombophlebitis of the femoral vein (disorder) + disease_ontology + DOID:12282 + femoral vein thrombophlebitis + + + + + + + + + A chronic pulmonary heart disease caused by a kyphoscoliosis. + + ICD9CM:416.1 + SNOMEDCT_2010_1_31:194886003 + SNOMEDCT_2010_1_31:45650007 + UMLS_CUI:C0152102 + Kyphoscoliotic heart disease (disorder) + disease_ontology + DOID:12325 + kyphoscoliotic heart disease @@ -6470,6 +13770,104 @@ A cor pulmonale that has a chronic disease course during which the right ventricle becomes hypertrophied. + + ICD9CM:416.8 + SNOMEDCT_2010_1_31:194887007 + SNOMEDCT_2010_1_31:194889005 + UMLS_CUI:C0155673 + disease_ontology + DOID:12326 + chronic pulmonary heart disease + + + + + + + + + + ICD9CM:456.4 + MSH:D014646 + SNOMEDCT_2010_1_31:155480003 + SNOMEDCT_2010_1_31:195480007 + SNOMEDCT_2010_1_31:46871008 + SNOMEDCT_2010_1_31:51070004 + UMLS_CUI:C0042341 + Scrotal varices + Scrotal varices (disorder) + Varicocele (disorder) + Varicocele [Ambiguous] + varicocele + disease_ontology + DOID:12337 + varicocele + + + + + + + + + + ICD9CM:448 + SNOMEDCT_2010_1_31:155446001 + SNOMEDCT_2010_1_31:155449008 + SNOMEDCT_2010_1_31:195250004 + SNOMEDCT_2010_1_31:195380006 + SNOMEDCT_2010_1_31:195390003 + SNOMEDCT_2010_1_31:266324004 + SNOMEDCT_2010_1_31:57223003 + SNOMEDCT_2010_1_31:58729003 + UMLS_CUI:C0155765 + disease of capillaries + disease_ontology + DOID:1271 + capillary disease + + + + + + + + + + MSH:D013684 + NCI:C28194 + SNOMEDCT_2010_1_31:112641009 + SNOMEDCT_2010_1_31:155449008 + SNOMEDCT_2010_1_31:247479008 + SNOMEDCT_2010_1_31:266324004 + SNOMEDCT_2010_1_31:276328002 + UMLS_CUI:C0039446 + telangiectasia + disease_ontology + DOID:1272 + telangiectasis + + + + + + + + + + + ICD9CM:437.0 + MSH:D002537 + NCI:C34459 + SNOMEDCT_2010_1_31:195220007 + SNOMEDCT_2010_1_31:266258005 + SNOMEDCT_2010_1_31:55382008 + UMLS_CUI:C0007775 + Cerebral atherosclerosis + Cerebral atherosclerosis (disorder) + disease_ontology + DOID:12720 + cerebral atherosclerosis @@ -6506,71 +13904,510 @@ + A disease affecting the cardiovascular system. + A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. + + DOID:73 + ICD9CM:429.2 + MSH:D002318 + NCI:C2931 + SNOMEDCT_2010_1_31:105980002 + SNOMEDCT_2010_1_31:155263000 + SNOMEDCT_2010_1_31:194707003 + SNOMEDCT_2010_1_31:195139006 + SNOMEDCT_2010_1_31:195594006 + SNOMEDCT_2010_1_31:266275004 + SNOMEDCT_2010_1_31:266336005 + SNOMEDCT_2010_1_31:49601007 + UMLS_CUI:C0007222 + cardiovascular system disease + disease of subdivision of hemolymphoid system + disease_ontology + DOID:1287 + cardiovascular system disease + + + + + + + + + + + ICD9CM:443.1 + MSH:D013919 + NCI:C35070 + OMIM:211480 + SNOMEDCT_2010_1_31:155432001 + SNOMEDCT_2010_1_31:195298008 + SNOMEDCT_2010_1_31:195299000 + SNOMEDCT_2010_1_31:195300008 + SNOMEDCT_2010_1_31:52403007 + UMLS_CUI:C0040021 + Buerger's disease + Presenile gangrene + Presenile gangrene (disorder) + Thromboangiitis obliterans + Thromboangiitis obliterans (disorder) + Thromboangiitis obliterans NOS (disorder) + Thromboangiitis obliterans [Buerger's disease] + disease_ontology + DOID:12918 + OMIM mapping confirmed by DO. [LS]. + thromboangiitis obliterans + + + + + + + + + + + + + + + + + + + + + + + + + A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown. + + ICD9CM:425.3 + MSH:D004695 + OMIM:226000 + OMIM:305300 + SNOMEDCT_2010_1_31:65457005 + UMLS_CUI:C0014117 + Elastomyofibrosis + Endocardial fibroelastosis + Endocardial fibroelastosis (disorder) + endocardial fibroelastosis + disease_ontology + DOID:12929 + OMIM mapping confirmed by DO. [SN]. + endocardial fibroelastosis + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment. +(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276) + An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently. + + MSH:D002311 + NCI:C84673 + OMIM:115200 + OMIM:300069 + OMIM:302045 + OMIM:601154 + OMIM:601493 + OMIM:601494 + OMIM:604145 + OMIM:604765 + OMIM:605362 + OMIM:606685 + OMIM:607482 + OMIM:607487 + OMIM:608569 + OMIM:609909 + OMIM:611407 + OMIM:611878 + OMIM:611879 + OMIM:611880 + OMIM:612158 + OMIM:612877 + OMIM:613122 + OMIM:613172 + OMIM:613252 + OMIM:613286 + OMIM:613424 + OMIM:613426 + OMIM:613642 + OMIM:613697 + SNOMEDCT_2010_1_31:195018001 + SNOMEDCT_2010_1_31:195021004 + SNOMEDCT_2010_1_31:389995008 + SNOMEDCT_2010_1_31:399020009 + SNOMEDCT_2010_1_31:74368002 + UMLS_CUI:C0007193 + Cardiomyopathy, congestive + primary dilated cardiomyopathy (disorder) + disease_ontology + Congestive cardiomyopathy + DOID:12930 + OMIM mapping confirmed by DO. [LS]. + dilated cardiomyopathy + + + + + + + + + A restrictive cardiomyopathy which results in fibrous lesions of right and left ventricle. It occurs typically in tropical and subtropical Africa. + + ICD9CM:425.0 + MSH:D004719 + NCI:C34585 + SNOMEDCT_2010_1_31:111507009 + SNOMEDCT_2010_1_31:123264005 + SNOMEDCT_2010_1_31:155351008 + SNOMEDCT_2010_1_31:266301006 + SNOMEDCT_2010_1_31:30293000 + SNOMEDCT_2010_1_31:398716006 + UMLS_CUI:C0553980 + (Becker's disease) or (obscure African cardiomyopathy) + African endomyocardial fibrosis + Becker's disease + Endomyocardial sclerosis + Obscure African cardiomyopathy (disorder) + disease_ontology + DOID:12932 + endomyocardial fibrosis + + + + + + + + + A dilated cardiomyopathy resulting from alcohol intoxication. + + ICD9CM:425.5 + MSH:D002310 + NCI:C53653 + SNOMEDCT_2010_1_31:155352001 + SNOMEDCT_2010_1_31:83521008 + UMLS_CUI:C0007192 + Alcohol-induced heart muscle disease + Alcoholic cardiomyopathy + Dilated cardiomyopathy secondary to alcohol (disorder) + disease_ontology + DOID:12935 + alcoholic cardiomyopathy + + + + + + + + + + + MSH:D016893 + SNOMEDCT_2010_1_31:195181000 + SNOMEDCT_2010_1_31:64586002 + UMLS_CUI:C0007282 + Carotid artery stenosis (disorder) + Stenosis, carotid artery + disease_ontology + DOID:13001 + carotid stenosis + + + + + + + + + + ICD9CM:435.3 + MSH:D014715 + SNOMEDCT_2010_1_31:155404005 + SNOMEDCT_2010_1_31:195196001 + SNOMEDCT_2010_1_31:195199008 + SNOMEDCT_2010_1_31:266314007 + SNOMEDCT_2010_1_31:394517009 + SNOMEDCT_2010_1_31:64009001 + UMLS_CUI:C0042568 + Vertebro-basilar insufficiency + Vertebrobasilar arterial insufficiency + Vertebrobasilar artery syndrome + Vertebrobasilar artery syndrome (disorder) + Vertebrobasilar insufficiency + disease_ontology + DOID:13003 + vertebrobasilar insufficiency + + + + + + + + + + ICD9CM:747.83 + MSH:D010547 + NCI:C85006 + OMIM:265380 + SNOMEDCT_2010_1_31:204507004 + SNOMEDCT_2010_1_31:206597007 + SNOMEDCT_2010_1_31:233815004 + SNOMEDCT_2010_1_31:35604006 + UMLS_CUI:C0031190 + Fetal circulation + Persistent fetal circulation + Persistent fetal circulation (disorder) + Persistent fetal circulation syndrome (disorder) + Persistent pulmonary hypertension of the newborn (disorder) + congenital alveolar capillary dysplasia with misalignment of pulmonary veins + persistent pulmonary hypertension of the newborn + disease_ontology + DOID:13042 + OMIM mapping confirmed by DO. [SN]. + persistent fetal circulation syndrome + + + + + + + + + + MSH:D020765 + UMLS_CUI:C0752138 + disease_ontology + DOID:13089 + intracranial arterial disease + + + + + + + + + + ICD9CM:362.32 + MSH:D015356 + NCI:C34436 + SNOMEDCT_2010_1_31:50821009 + UMLS_CUI:C0006123 + Arterial retinal branch occlusion (disorder) + Retinal Arterial Branch Occlusion + Retinal arterial branch occlusion + disease_ontology + DOID:13094 + branch retinal artery occlusion + + + + + + + + + + MSH:D014715 + SNOMEDCT_2010_1_31:195198000 + SNOMEDCT_2010_1_31:34781003 + UMLS_CUI:C0042560 + Vertebral artery syndrome + Vertebral artery syndrome (disorder) + disease_ontology + DOID:13095 + vertebral artery insufficiency + + + + + + + + + + + MSH:D018860 + OMIM:182410 + SNOMEDCT_2010_1_31:238776001 + UMLS_CUI:C0282492 + Idiopathic livedo reticularis with systemic involvement (disorder) + disease_ontology + DOID:13096 + Sneddon syndrome + + + + + + + + + + + MSH:D002537 + UMLS_CUI:C0007771 + disease_ontology + DOID:13097 + intracranial arteriosclerosis + + + + + + + + + + ICD9CM:362.31 + MSH:D015356 + NCI:C34456 + SNOMEDCT_2010_1_31:38742007 + UMLS_CUI:C0007688 + central retinal artery occlusion + central retinal artery occlusion (disorder) + disease_ontology + DOID:13098 + central retinal artery occlusion + + + + + + + + + + ICD9CM:437.5 + MSH:D009072 + NCI:C84895 + OMIM:252350 + SNOMEDCT_2010_1_31:69116000 + SNOMEDCT_2010_1_31:89142007 + UMLS_CUI:C0026654 + Moyamoya disease + Moyamoya disease (disorder) + progressive intracranial arterial occlusion (disorder) + disease_ontology + DOID:13099 + OMIM mapping confirmed by DO. [SN]. + Moyamoya disease - + - - - - - - - - - - - - - - - - - - - A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown. + + + + MSH:D020301 + UMLS_CUI:C0751895 + disease_ontology + DOID:13100 + intracranial vasospasm - + - - - - - - - - - - - - - - - - - - - - - - - A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment. -(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276) + + + + DOID:13130 + DOID:13131 + DOID:13132 + ICD9CM:642.50 + UMLS_CUI:C0156669 + Severe pre-eclampsia, with delivery + antepartum severe pre-eclampsia + postpartum severe pre-eclampsia + disease_ontology + DOID:13129 + severe pre-eclampsia - + - - - A dilated cardiomyopathy resulting from alcohol intoxication. + + + + MSH:D017359 + NCI:C84750 + SNOMEDCT_2010_1_31:199010001 + SNOMEDCT_2010_1_31:95605009 + UMLS_CUI:C0162739 + HELLP syndrome (disorder) + syndrome of haemolysis, elevated liver enzymes and low platelet + disease_ontology + DOID:13133 + HELLP syndrome + + + + + + + + + + ICD9CM:405.1 + NCI:C3658 + SNOMEDCT_2010_1_31:194785008 + SNOMEDCT_2010_1_31:194787000 + SNOMEDCT_2010_1_31:44111003 + UMLS_CUI:C0155620 + disease_ontology + DOID:13143 + benign secondary hypertension + + + + + + + + + + ICD9CM:405.11 + UMLS_CUI:C0155621 + disease_ontology + DOID:13145 + benign renovascular hypertension @@ -6605,6 +14442,14 @@ + + ICD9CM:426.51 + SNOMEDCT_2010_1_31:46319007 + UMLS_CUI:C0155704 + Right bundle branch block with left posterior fascicular block (disorder) + disease_ontology + DOID:13209 + right bundle branch block (disease) @@ -6613,6 +14458,198 @@ + An autoimmune disease of cardiovascular system that causes chronic inflammation in blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis. + + ICD9CM:136.1 + MSH:D001528 + NCI:C34416 + OMIM:109650 + SNOMEDCT_2010_1_31:154424000 + SNOMEDCT_2010_1_31:310701003 + SNOMEDCT_2010_1_31:41225007 + UMLS_CUI:C0004943 + Adamantiades-Behcet disease + Behcet syndrome + Behet's syndrome (disorder) + triple symptom complex + disease_ontology + Behcet's syndrome + DOID:13241 + OMIM mapping confirmed by DO. [SN]. + Behcet's disease + + + + + + + + + + ICD9CM:446.5 + MSH:D013700 + NCI:C35065 + OMIM:187360 + SNOMEDCT_2010_1_31:155442004 + SNOMEDCT_2010_1_31:195354005 + SNOMEDCT_2010_1_31:195355006 + SNOMEDCT_2010_1_31:195356007 + SNOMEDCT_2010_1_31:195357003 + SNOMEDCT_2010_1_31:400130008 + SNOMEDCT_2010_1_31:414341000 + SNOMEDCT_2010_1_31:87511001 + UMLS_CUI:C0039483 + Giant cell Arteritis + Giant cell arteritis + Giant cell arteritis (disorder) + Giant cell arteritis NOS (disorder) + Horton's disease + Temporal arteritis (disorder) + giant cell arteritis + disease_ontology + DOID:13375 + OMIM mapping confirmed by DO. [LS]. + temporal arteritis + + + + + + + + + + ICD9CM:446.1 + MSH:D009080 + NCI:C34825 + OMIM:611775 + SNOMEDCT_2010_1_31:155444003 + SNOMEDCT_2010_1_31:195348009 + SNOMEDCT_2010_1_31:195349001 + SNOMEDCT_2010_1_31:75053002 + UMLS_CUI:C0026691 + Kawasaki disease + Kawasaki's disease + MLNS + acute febrile MCLS + acute febrile mucocutaneous lymph node syndrome (disorder) + acute febrile mucocutaneous lymph node syndrome NOS (disorder) + acute febrile mucocutaneous lymph node syndrome [MCLS] + mucocutaneous lymph node syndrome + disease_ontology + DOID:13378 + OMIM mapping confirmed by DO. [SN]. + Kawasaki disease + + + + + + + + + + ICD9CM:433.0 + SNOMEDCT_2010_1_31:155396001 + SNOMEDCT_2010_1_31:195180004 + SNOMEDCT_2010_1_31:78658006 + UMLS_CUI:C0265098 + disease_ontology + DOID:13446 + basilar artery occlusion + + + + + + + + + + DOID:13592 + MSH:D004461 + NCI:C87167 + SNOMEDCT_2010_1_31:156111007 + SNOMEDCT_2010_1_31:15938005 + SNOMEDCT_2010_1_31:198988006 + SNOMEDCT_2010_1_31:198989003 + SNOMEDCT_2010_1_31:198996001 + UMLS_CUI:C0013537 + Eclampsia (disorder) + Eclampsia NOS (disorder) + Eclampsia in puerperium (disorder) + Eclampsia unspecified (disorder) + Eclampsia, postpartum + Postpartum eclampsia + eclampsia + disease_ontology + DOID:13593 + eclampsia + + + + + + + + + + UMLS_CUI:C0155618 + disease_ontology + DOID:13730 + malignant renovascular hypertension + + + + + + + + + + + ICD9CM:405.0 + SNOMEDCT_2010_1_31:194784007 + SNOMEDCT_2010_1_31:49863005 + SNOMEDCT_2010_1_31:89242004 + UMLS_CUI:C0155617 + disease_ontology + DOID:13731 + malignant secondary hypertension + + + + + + + + + + ICD9CM:573.4 + SNOMEDCT_2010_1_31:17890003 + UMLS_CUI:C0151731 + hepatic infarction + hepatic infarction (disorder) + disease_ontology + DOID:13738 + infarct of liver + + + + + + + + + + ICD9CM:573.0 + SNOMEDCT_2010_1_31:34736002 + UMLS_CUI:C0156195 + chronic passive congestion of liver + chronic passive congestion of liver (disorder) + disease_ontology + DOID:13739 + nutmeg liver @@ -6621,6 +14658,21 @@ + + ICD9CM:397.0 + SNOMEDCT_2010_1_31:155289000 + SNOMEDCT_2010_1_31:194745002 + SNOMEDCT_2010_1_31:266282000 + SNOMEDCT_2010_1_31:49699002 + UMLS_CUI:C0264776 + RH. tricuspid valve disease + Rheumatic disease of tricuspid valve (disorder) + Rheumatic tricuspid valve disease NOS (disorder) + Tricuspid disease + disease of tricuspid valve + disease_ontology + DOID:13834 + rheumatic tricuspid valve disease @@ -6660,6 +14712,100 @@ A heart conduction disease characterized by inappropriate sinus rates (e.g. sinus bradycardia or sinus pause). + + MSH:D012804 + NCI:C62244 + SNOMEDCT_2010_1_31:155373001 + SNOMEDCT_2010_1_31:266307005 + SNOMEDCT_2010_1_31:36083008 + UMLS_CUI:C0037052 + disease_ontology + DOID:13884 + sick sinus syndrome + + + + + + + + + + ICD9CM:441.2 + MSH:D017545 + NCI:C27001 + OMIM:132900 + OMIM:611788 + SNOMEDCT_2010_1_31:155421001 + SNOMEDCT_2010_1_31:195259003 + SNOMEDCT_2010_1_31:433068007 + SNOMEDCT_2010_1_31:74883004 + UMLS_CUI:C0162872 + Thoracic Aortic Aneurysm + Thoracic aortic aneurysm + Thoracic aortic aneurysm without mention of rupture + Thoracic aortic aneurysm without mention of rupture (disorder) + Thoracic aortic aneurysm without rupture + disease_ontology + DOID:14004 + OMIM mapping confirmed by DO. [SN]. + thoracic aortic aneurysm + thoracic aortic aneurysm disease + + + + + + + + + + ICD9CM:442.83 + SNOMEDCT_2010_1_31:70405009 + UMLS_CUI:C0155747 + disease_ontology + DOID:14006 + splenic artery aneurysm + splenic artery aneurysm disease + + + + + + + + + + ICD9CM:747.22 + SNOMEDCT_2010_1_31:204431007 + SNOMEDCT_2010_1_31:204438001 + UMLS_CUI:C0345010 + Atresia and stenosis of aorta (disorder) + Atresia or stenosis of aorta NOS (disorder) + Congenital atresia and stenosis of aorta + disease_ontology + DOID:14037 + aorta atresia + + + + + + + + + + + ICD9CM:440.1 + SNOMEDCT_2010_1_31:155416004 + SNOMEDCT_2010_1_31:45281005 + UMLS_CUI:C0155734 + Atherosclerosis of renal artery + Atherosclerosis of renal artery (disorder) + renal atherosclerosis + disease_ontology + DOID:14092 + renal artery atheroma @@ -6668,6 +14814,31 @@ + + MSH:D018438 + UMLS_CUI:C0242645 + disease_ontology + DOID:14121 + blue toe syndrome + + + + + + + + + A congestive heart failure caused by a rheumatic fever. + + ICD9CM:398.91 + SNOMEDCT_2010_1_31:82523003 + UMLS_CUI:C0155582 + Congestive rheumatic heart failure (disorder) + Rheumatic heart failure + Rheumatic heart failure (congestive) + disease_ontology + DOID:14172 + rheumatic congestive heart failure @@ -6717,6 +14888,94 @@ A disease in which an abnormal structure in a pulmonary valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve. + A pulmonary valve disease that occurs when the pulmonary valve is not strong enough to prevent backflow into the right ventricle. If it is secondary to pulmonary hypertension it is referred to as a Graham Steell murmur. + + DOID:11210 + ICD9CM:518.5 + UMLS_CUI:C0034076 + Pulmonic insufficiency NOS + Pulmonic valve regurgitation (disorder) + pulmonary incompetence + pulmonary incompetence, non-rheumatic (disorder) + pulmonary insufficiency following trauma and surgery + pulmonary regurg. + pulmonary regurgitation + disease_ontology + DOID:14265 + pulmonary valve insufficiency + + + + + + + + + + ICD9CM:453.1 + SNOMEDCT_2010_1_31:155456002 + SNOMEDCT_2010_1_31:155491005 + SNOMEDCT_2010_1_31:31268005 + UMLS_CUI:C0152250 + Thrombophlebitis migrans (disorder) + disease_ontology + DOID:14392 + thrombophlebitis migrans + + + + + + + + + + + MSH:D019559 + NCI:C62578 + SNOMEDCT_2010_1_31:87730004 + UMLS_CUI:C0343084 + Capillary leak syndrome (disorder) + disease_ontology + DOID:14400 + capillary leak syndrome + + + + + + + + + + ICD9CM:708.5 + SNOMEDCT_2010_1_31:73098005 + UMLS_CUI:C0152230 + Cholinergic urticaria (disorder) + disease_ontology + DOID:14443 + cholinergic urticaria + + + + + + + + + + ICD9CM:362.33 + NCI:C35192 + SNOMEDCT_2010_1_31:193376004 + SNOMEDCT_2010_1_31:776009 + UMLS_CUI:C0154839 + Partial Retinal Arterial Occlusion + Partial arterial retinal occlusion (disorder) + Partial retinal arterial occlusion + Retinal partial arterial occlusion NOS (disorder) + disease_ontology + DOID:14522 + partial arterial retinal occlusion @@ -6725,6 +14984,36 @@ + + ICD9CM:416.0 + MSH:C536282 + OMIM:178600 + OMIM:265400 + SNOMEDCT_2010_1_31:155328008 + SNOMEDCT_2010_1_31:26174007 + SNOMEDCT_2010_1_31:266293003 + UMLS_CUI:C0152171 + primary pulmonary hypertension + primary pulmonary hypertension (disorder) + pulmonary hypertension (& [primary]) + pulmonary hypertension, idiopathic + disease_ontology + DOID:14557 + OMIM mapping confirmed by DO. [SN]. + primary pulmonary hypertension + + + + + + + + + + UMLS_CUI:C1135215 + disease_ontology + DOID:1460 + atheroembolism of kidney @@ -6734,6 +15023,130 @@ An embolism due to an embolus made of cholesterol. + + ICD9CM:445 + MSH:D017700 + SNOMEDCT_2010_1_31:10690002 + UMLS_CUI:C0149649 + disease_ontology + DOID:1461 + cholesterol embolism + + + + + + + + + + MSH:D054179 + NCI:C84758 + OMIM:106100 + OMIM:610618 + SNOMEDCT_2010_1_31:82966003 + UMLS_CUI:C0019243 + HANE + Hereditary angioedema + Hereditary angioneurotic edema (disorder) + disease_ontology + DOID:14735 + OMIM mapping confirmed by DO. [SN]. + hereditary angioedema + + + + + + + + + + ICD9CM:708.4 + SNOMEDCT_2010_1_31:51247001 + UMLS_CUI:C0157743 + Vibratory urticaria (disorder) + disease_ontology + DOID:1554 + vibratory urticaria + + + + + + + + + + ICD9CM:708.8 + MSH:D014581 + SNOMEDCT_2010_1_31:201267004 + SNOMEDCT_2010_1_31:201271001 + SNOMEDCT_2010_1_31:267817001 + UMLS_CUI:C0029839 + disease_ontology + DOID:1555 + urticaria + + + + + + + + + + MSH:D000799 + SNOMEDCT_2010_1_31:157756002 + SNOMEDCT_2010_1_31:269433002 + SNOMEDCT_2010_1_31:400075008 + SNOMEDCT_2010_1_31:41291007 + SNOMEDCT_2010_1_31:82966003 + UMLS_CUI:C0002994 + Angioedema (disorder) + Angioneurotic oedema + Giant urticaria + Giant urticaria (disorder) + QUINCKE'S EDEMA + Quincke's edema + angioedema + angioneurotic edema + giant urticaria + disease_ontology + DOID:1558 + angioedema + + + + + + + + + + MSH:D006978 + NCI:C85044 + SNOMEDCT_2010_1_31:123799005 + SNOMEDCT_2010_1_31:194790006 + UMLS_CUI:C0020545 + Renovascular hypertension (disorder) + disease_ontology + DOID:1591 + renovascular hypertension + + + + + + + + + + NCI:C40381 + UMLS_CUI:C1511284 + disease_ontology + DOID:1637 + breast angiomatosis @@ -6783,6 +15196,47 @@ A disease in which some disorder of the aortic valve leads prevents it from opening properly during left ventricular systole, occasioning disturbance in the anterograd blood flow through the valve. + Aortic valve stenosis is a aortic valve disease caused by the incomplete opening of the aortic valve. The aortic valve controls the direction of blood flow from the left ventricle to the aorta. When in good working order, the aortic valve does not impede the flow of blood between these two spaces. Under some circumstances, the aortic valve becomes narrower than normal, impeding the flow of blood. This is known as aortic valve stenosis, or aortic stenosis, often abbreviated AS. + + MSH:D001024 + NCI:C50462 + SNOMEDCT_2010_1_31:390722003 + SNOMEDCT_2010_1_31:60573004 + UMLS_CUI:C0003507 + AS + Aortic stenosis + Aortic valve stenosis (disorder) + aortic valve stenosis + disease_ontology + DOID:1712 + aortic valve stenosis + + + + + + + + + + ICD9CM:362.3 + ICD9CM:362.30 + NCI:C34980 + SNOMEDCT_2010_1_31:155111000 + SNOMEDCT_2010_1_31:193373007 + SNOMEDCT_2010_1_31:193380009 + SNOMEDCT_2010_1_31:267717005 + SNOMEDCT_2010_1_31:73757007 + UMLS_CUI:C0035326 + Retinal vasc. occlusion + Retinal vascular Occlusion + Retinal vascular occlusion (disorder) + Retinal vascular occlusion NOS (disorder) + Retinal vascular occlusion, unspecified + Unspecified retinal vascular occlusion (disorder) + disease_ontology + DOID:1729 + retinal vascular occlusion @@ -6832,6 +15286,21 @@ A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve. + Mitral valve stenosis is a rheumatic disease of mitral valve characterized by the narrowing of the orifice of the mitral valve of the heart. Most cases of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease. Less common causes of mitral stenosis are calcification of the mitral valve leaflets, and as a form of congenital heart disease. However, there are primary causes of mitral stenosis that emanate from a cleft mitral valve. Other causes include Bacterial endocarditis where the vegetations may favor increase risk of stenosis. + + MSH:D008946 + NCI:C50654 + SNOMEDCT_2010_1_31:155277002 + SNOMEDCT_2010_1_31:194725005 + SNOMEDCT_2010_1_31:79619009 + UMLS_CUI:C0026269 + Mitral stenosis + Mitral stenosis NOS + Mitral valve stenosis (disorder) + mitral valve stenosis + disease_ontology + DOID:1754 + mitral valve stenosis @@ -6870,6 +15339,21 @@ A disease affecting a blood vessel. Reorganization of the vascular diseases, and writing of Aristotelian definitions, is still ongoing. + A cardiovascular system disease that primarily affects the blood vessels. + + DOID:2869 + DOID:45 + MSH:D014652 + NCI:C35117 + SNOMEDCT_2010_1_31:27550009 + UMLS_CUI:C0042373 + UMLS_CUI:C0264951 + arteriopathy + internal elastic lamina + disease_ontology + Arterial disease + DOID:178 + vascular disease @@ -6895,6 +15379,15 @@ A disease characterized by an inflammation of the pericardium. + A heart disease that is characterized by an inflammation of the pericardium and has_symptom chest pain. + + MSH:D010493 + NCI:C34915 + SNOMEDCT_2010_1_31:3238004 + UMLS_CUI:C0031046 + disease_ontology + DOID:1787 + pericarditis @@ -6902,6 +15395,7 @@ + @@ -6914,6 +15408,18 @@ A chronic pericarditis due to rheumatic fever. + + ICD9CM:393 + SNOMEDCT_2010_1_31:155287003 + SNOMEDCT_2010_1_31:194719006 + SNOMEDCT_2010_1_31:194723003 + SNOMEDCT_2010_1_31:78069008 + UMLS_CUI:C0155561 + chronic rheumatic pericarditis (disorder) + chronic rheumatic pericarditis NOS (disorder) + disease_ontology + DOID:1869 + chronic rheumatic pericarditis @@ -6948,6 +15454,19 @@ A congenital disease involving the narrowing (stenosis) of aorta, hindering the opening of the aortic valve. Supravalvular aortic stenosis is not classified as an aortic valve stenosis: although the narrowing of the section of the aorta at the exit of the aortic valve implies some improper opening of the aortic valve, the aortic valve is (in general) healthy (there is no disorder nor pathological process inside it). However, this improper opening of the aortic valve is a pathological process that happens inside the heart; therefore, supravalvular aortic stenosis is classified as a heart disease. + + MSH:D021921 + NCI:C85176 + OMIM:185500 + OMIM:194050 + SNOMEDCT_2010_1_31:204436002 + SNOMEDCT_2010_1_31:268185002 + UMLS_CUI:C0003499 + Supra-valvular aortic stenosis + Supravalvar aortic stenosis (disorder) + disease_ontology + DOID:1929 + supravalvular aortic stenosis @@ -6972,6 +15491,40 @@ + + ICD9CM:440 + MSH:D050197 + NCI:C35768 + SNOMEDCT_2010_1_31:155382007 + SNOMEDCT_2010_1_31:155414001 + SNOMEDCT_2010_1_31:194848007 + SNOMEDCT_2010_1_31:195251000 + SNOMEDCT_2010_1_31:266318005 + SNOMEDCT_2010_1_31:38716007 + UMLS_CUI:C0004153 + disease_ontology + DOID:1936 + atherosclerosis + + + + + + + + + + ICD9CM:435.0 + MSH:D014715 + NCI:C34413 + SNOMEDCT_2010_1_31:195197005 + SNOMEDCT_2010_1_31:64009001 + UMLS_CUI:C0004812 + Basilar artery syndrome + Basilar artery syndrome (disorder) + disease_ontology + DOID:223 + basilar artery insufficiency @@ -6990,16 +15543,97 @@ + A brain ischemia that is part of a transient disease course. + + DOID:2315 + MSH:D002546 + NCI:C50781 + SNOMEDCT_2010_1_31:155404005 + SNOMEDCT_2010_1_31:195196001 + SNOMEDCT_2010_1_31:195207009 + SNOMEDCT_2010_1_31:266257000 + SNOMEDCT_2010_1_31:266314007 + SNOMEDCT_2010_1_31:313242003 + SNOMEDCT_2010_1_31:38609002 + UMLS_CUI:C0007787 + UMLS_CUI:C0155728 + TIA + TIA - Transient ischaemic attack + TRANSIENT ISCHEMIC ATTACK + Transient cerebral ischaemia + Transient cerebral ischaemia NOS + Transient cerebral ischemia (disorder) [Ambiguous] + Transient ischemic attacks (disorder) + transient ischemic attack + disease_ontology + DOID:224 + transient cerebral ischemia - + + An ischemia of the brain. - + + MSH:D002545 + SNOMEDCT_2010_1_31:11890005 + SNOMEDCT_2010_1_31:193049009 + SNOMEDCT_2010_1_31:389100007 + UMLS_CUI:C0007786 + Ischaemic encephalopathy + Ischemic encephalopathy (disorder) + disease_ontology + DOID:2316 + brain ischemia + + + + + + + + + + ICD9CM:440.9 + NCI:C35767 + SNOMEDCT_2010_1_31:367108003 + SNOMEDCT_2010_1_31:39823006 + UMLS_CUI:C0017327 + Generalised atherosclerosis + Generalized and unspecified atherosclerosis + Generalized atherosclerosis (disorder) + disease_ontology + DOID:2347 + generalized atherosclerosis + + + + + + + + + + NCI:C34403 + NCI:C35771 + SNOMEDCT_2010_1_31:195121002 + SNOMEDCT_2010_1_31:195251000 + SNOMEDCT_2010_1_31:39468009 + UMLS_CUI:C0003972 + Arteriosclerotic Cardiovascular disease + Arteriosclerotic cardiovascular disease + Arteriosclerotic cardiovascular disease, NOS + Atherosclerotic Cardiovascular disease + Atherosclerotic cardiovascular disease + Cardiovascular arteriosclerosis unspecified (disorder) + disease_ontology + DOID:2348 + arteriosclerotic cardiovascular disease + @@ -7023,6 +15657,54 @@ + + MSH:D001161 + NCI:C34398 + SNOMEDCT_2010_1_31:107671003 + SNOMEDCT_2010_1_31:155414001 + SNOMEDCT_2010_1_31:155418003 + SNOMEDCT_2010_1_31:195251000 + SNOMEDCT_2010_1_31:195257001 + SNOMEDCT_2010_1_31:266318005 + SNOMEDCT_2010_1_31:28960008 + SNOMEDCT_2010_1_31:72092001 + UMLS_CUI:C0003850 + Arteriosclerosis (morphologic abnormality) + Arteriosclerosis NOS + Arteriosclerotic vascular disease (disorder) + Arteriosclerotic vascular disease NOS + Arteriosclerotic vascular disease NOS (disorder) + arteriosclerosis + disease_ontology + DOID:2349 + arteriosclerosis + + + + + + + + + + DOID:12820 + DOID:2363 + DOID:2720 + ICD9CM:459.1 + MSH:D011186 + SNOMEDCT_2010_1_31:155460004 + SNOMEDCT_2010_1_31:20427003 + SNOMEDCT_2010_1_31:410013001 + UMLS_CUI:C0032807 + UMLS_CUI:C1135219 + UMLS_CUI:C1135220 + UMLS_CUI:C1135221 + Postphlebetic syndrome with inflammation + Postphlebetic syndrome with ulcer + Postphlebetic syndrome with ulcer and inflammation + disease_ontology + DOID:2364 + postphlebitic syndrome @@ -7031,6 +15713,17 @@ + + ICD9CM:593.81 + NCI:C35338 + SNOMEDCT_2010_1_31:16934004 + SNOMEDCT_2010_1_31:197814004 + SNOMEDCT_2010_1_31:266559003 + UMLS_CUI:C0268790 + vascular disorder of kidney + disease_ontology + DOID:2388 + renal vascular disease @@ -7051,6 +15744,22 @@ A disposition that an aneurysm disorder will lead to pathological processes. DOID label 'aneurysm disease' changed for homogeneization purpose in CVDO. + A vascular disease that is characterized by a localized, blood-filled balloon-like bulge in the wall of a blood vessel. + + ICD9CM:442.9 + MSH:D000783 + NCI:C26693 + SNOMEDCT_2010_1_31:134342004 + SNOMEDCT_2010_1_31:155425005 + SNOMEDCT_2010_1_31:155428007 + SNOMEDCT_2010_1_31:195292009 + SNOMEDCT_2010_1_31:362727005 + SNOMEDCT_2010_1_31:432119003 + SNOMEDCT_2010_1_31:85659009 + UMLS_CUI:C0002940 + disease_ontology + DOID:2403 + aneurysm (disease) @@ -7059,6 +15768,33 @@ + + NCI:C35170 + SNOMEDCT_2010_1_31:57534004 + UMLS_CUI:C0154833 + retina circulation disorder + disease_ontology + DOID:2462 + retinal vascular disease + + + + + + + + + + MSH:D020252 + NCI:C84724 + SNOMEDCT_2010_1_31:412795008 + SNOMEDCT_2010_1_31:43935004 + UMLS_CUI:C0267211 + Watermelon stomach (disorder) + gastric antral vascular ectasia (disorder) + disease_ontology + DOID:2493 + gastric antral vascular ectasia @@ -7067,6 +15803,75 @@ + + DOID:12071 + MSH:D016888 + SNOMEDCT_2010_1_31:71072006 + UMLS_CUI:C0085411 + UMLS_CUI:C0156091 + angiodysplasia of stomach and duodenum with hemorrhage + disease_ontology + DOID:2494 + angiodysplasia + + + + + + + + + + + NCI:C5432 + UMLS_CUI:C1334237 + intracranial Cavernoma + disease_ontology + DOID:2516 + intracranial cavernous angioma + + + + + + + + + + + ICD9CM:228.02 + NCI:C3633 + SNOMEDCT_2010_1_31:189196005 + SNOMEDCT_2010_1_31:93468003 + UMLS_CUI:C0154050 + Angioma of intracranial Structure + hemangioma of intracranial structure (disorder) + hemangioma of intracranial structures + hemangioma of intracranial structures (disorder) + disease_ontology + DOID:2517 + intracranial structure hemangioma + + + + + + + + + + ICD9CM:228.04 + NCI:C3635 + SNOMEDCT_2010_1_31:189197001 + SNOMEDCT_2010_1_31:93467008 + UMLS_CUI:C0154052 + hemangioma of intra-abdominal structure (disorder) + hemangioma of intra-abdominal structures + hemangioma of intra-abdominal structures (disorder) + hemangioma, Intra-abdominal + disease_ontology + DOID:254 + hemangioma of intra-abdominal structure @@ -7075,6 +15880,62 @@ + + ICD9CM:228.0 + ICD9CM:228.00 + MSH:D006391 + NCI:C3085 + SNOMEDCT_2010_1_31:154625006 + SNOMEDCT_2010_1_31:189192007 + SNOMEDCT_2010_1_31:189193002 + SNOMEDCT_2010_1_31:189194008 + SNOMEDCT_2010_1_31:189199003 + SNOMEDCT_2010_1_31:189863005 + SNOMEDCT_2010_1_31:2099007 + SNOMEDCT_2010_1_31:253053003 + SNOMEDCT_2010_1_31:254822005 + SNOMEDCT_2010_1_31:269646001 + SNOMEDCT_2010_1_31:367337005 + SNOMEDCT_2010_1_31:400210000 + SNOMEDCT_2010_1_31:93474003 + UMLS_CUI:C0018916 + disease_ontology + DOID:255 + hemangioma + + + + + + + + + + MSH:D020293 + NCI:C34653 + UMLS_CUI:C0018202 + disease_ontology + DOID:2555 + granulomatous angiitis + + + + + + + + + + + NCI:C3869 + SNOMEDCT_2010_1_31:235879002 + SNOMEDCT_2010_1_31:93469006 + UMLS_CUI:C0238246 + Angioma of Liver + hepatic angioma (disorder) + disease_ontology + DOID:271 + hemangioma of liver @@ -7083,6 +15944,14 @@ + + NCI:C35442 + SNOMEDCT_2010_1_31:235878005 + UMLS_CUI:C0400923 + vascular disorder of liver (disorder) + disease_ontology + DOID:272 + hepatic vascular disease @@ -7107,6 +15976,69 @@ + + MSH:D001157 + SNOMEDCT_2010_1_31:2929001 + UMLS_CUI:C0003838 + Arterial occlusive disease + disease_ontology + DOID:2868 + arterial occlusive disease + + + + + + + + + + MSH:D012078 + UMLS_CUI:C0035066 + renal artery obstruction + disease_ontology + DOID:2972 + renal artery obstruction + + + + + + + + + A vasculitits that is systemic vasculitis realized as blood vessel inflammation and has_symptom asthma along with hay fever, rash and gastrointestinal bleeding. + + MSH:C531653 + MSH:D015267 + NCI:C34481 + SNOMEDCT_2010_1_31:195362002 + SNOMEDCT_2010_1_31:82275008 + UMLS_CUI:C0008728 + Allergic Granulomatous Angiitis + Allergic granulomatosis angiitis (disorder) + Churg-Strauss vasculitis + disease_ontology + DOID:3049 + Churg-Strauss syndrome + + + + + + + + + + MSH:D002573 + SNOMEDCT_2010_1_31:413577001 + SNOMEDCT_2010_1_31:54995001 + SNOMEDCT_2010_1_31:95409006 + UMLS_CUI:C0007856 + Arterial thoracic outlet syndrome due to cervical rib + disease_ontology + DOID:3102 + cervical rib syndrome @@ -7115,6 +16047,38 @@ + + MSH:D013901 + NCI:C85188 + SNOMEDCT_2010_1_31:128210009 + SNOMEDCT_2010_1_31:193106006 + SNOMEDCT_2010_1_31:193107002 + SNOMEDCT_2010_1_31:193108007 + SNOMEDCT_2010_1_31:2040007 + SNOMEDCT_2010_1_31:212769008 + SNOMEDCT_2010_1_31:393578000 + UMLS_CUI:C0039984 + TOS - Thoracic outlet syndrome + disease_ontology + DOID:3103 + thoracic outlet syndrome + + + + + + + + + An ischemia occurring in the spinal cord. + + MSH:D020760 + SNOMEDCT_2010_1_31:371029002 + UMLS_CUI:C0752130 + Ischaemic disorder of spinal cord + disease_ontology + DOID:324 + spinal cord ischemia @@ -7123,6 +16087,12 @@ + + MSH:D020758 + UMLS_CUI:C0752127 + disease_ontology + DOID:325 + spinal cord vascular disease @@ -7138,6 +16108,36 @@ A pathological process of restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism. + + MSH:D007511 + NCI:C34738 + SNOMEDCT_2010_1_31:52674009 + UMLS_CUI:C0022116 + ischemia + disease_ontology + DOID:326 + ischemia + + + + + + + + + + ICD9CM:414.11 + MSH:D003323 + SNOMEDCT_2010_1_31:373139003 + SNOMEDCT_2010_1_31:50570003 + UMLS_CUI:C0010051 + Aneurysm of coronary vessels + Aneurysmal lesion of coronary artery + Arteriovenous aneurysm of coronary vessels + disease_ontology + DOID:3362 + coronary aneurysm + coronary aneurysm disease @@ -7166,6 +16166,22 @@ + + ICD9CM:414.0 + MSH:D003324 + NCI:C35505 + SNOMEDCT_2010_1_31:155315001 + SNOMEDCT_2010_1_31:155316000 + SNOMEDCT_2010_1_31:194795001 + SNOMEDCT_2010_1_31:194841001 + SNOMEDCT_2010_1_31:266231003 + SNOMEDCT_2010_1_31:266290000 + SNOMEDCT_2010_1_31:41702007 + SNOMEDCT_2010_1_31:53741008 + UMLS_CUI:C0010054 + disease_ontology + DOID:3363 + coronary arteriosclerosis @@ -7175,6 +16191,18 @@ An ischemic heart disease with narrowing of the coronary arteries. + + MSH:D003327 + NCI:C26732 + SNOMEDCT_2010_1_31:41702007 + SNOMEDCT_2010_1_31:53741008 + UMLS_CUI:C0010068 + CHD (coronary heart disease) + CHD - Coronary heart disease + Coronary disease + disease_ontology + DOID:3393 + coronary heart disease @@ -7216,6 +16244,58 @@ A disease characterized by reduced blood supply to the heart, occasioning pathological processes in the heart. + An extrinsic cardiomyopathy that is characterized by reduced blood supply to the cardiac muscles. + + DOID:10506 + DOID:9420 + ICD9CM:410-414.99 + ICD9CM:414.9 + MSH:D017202 + NCI:C50625 + SNOMEDCT_2010_1_31:155303000 + SNOMEDCT_2010_1_31:155315001 + SNOMEDCT_2010_1_31:155318004 + SNOMEDCT_2010_1_31:155322009 + SNOMEDCT_2010_1_31:194795001 + SNOMEDCT_2010_1_31:194852007 + SNOMEDCT_2010_1_31:194878003 + SNOMEDCT_2010_1_31:195540001 + SNOMEDCT_2010_1_31:233822007 + SNOMEDCT_2010_1_31:2610009 + SNOMEDCT_2010_1_31:266290000 + SNOMEDCT_2010_1_31:266291001 + SNOMEDCT_2010_1_31:271430002 + SNOMEDCT_2010_1_31:32598000 + SNOMEDCT_2010_1_31:413838009 + SNOMEDCT_2010_1_31:413844008 + SNOMEDCT_2010_1_31:414545008 + SNOMEDCT_2010_1_31:414795007 + SNOMEDCT_2010_1_31:41702007 + SNOMEDCT_2010_1_31:84537008 + UMLS_CUI:C0151744 + UMLS_CUI:C0264694 + chronic myocardial ischaemia + myocardial ischemia + disease_ontology + DOID:3394 + ischemic heart disease + + + + + + + + + + MSH:D002340 + NCI:C84476 + SNOMEDCT_2010_1_31:371160000 + UMLS_CUI:C0007273 + disorder of carotid artery (disorder) + disease_ontology + DOID:3407 + carotid artery disease @@ -7224,6 +16304,13 @@ + + ICD9CM:443.81 + SNOMEDCT_2010_1_31:195624006 + UMLS_CUI:C0031115 + disease_ontology + DOID:341 + peripheral vascular disease @@ -7231,6 +16318,7 @@ + @@ -7238,6 +16326,32 @@ A thrombosis occurring in a carotid artery. + + MSH:D002341 + SNOMEDCT_2010_1_31:195181000 + SNOMEDCT_2010_1_31:86003009 + UMLS_CUI:C0007274 + Carotid artery thrombosis + Carotid artery thrombosis (disorder) + disease_ontology + DOID:3410 + carotid artery thrombosis + + + + + + + + + + ICD9CM:442.82 + SNOMEDCT_2010_1_31:40136003 + UMLS_CUI:C0155746 + disease_ontology + DOID:342 + subclavian artery aneurysm + subclavian artery aneurysm disease @@ -7256,7 +16370,13 @@ + + MSH:D020520 + UMLS_CUI:C0751955 + disease_ontology + DOID:3454 An infarction occurring in the brain. + brain infarction @@ -7272,6 +16392,139 @@ A pathological process of disturbance in the blood supply to the brain, causing a loss of brain function. + + MSH:D020521 + NCI:C3390 + OMIM:601367 + SNOMEDCT_2010_1_31:155388006 + SNOMEDCT_2010_1_31:155405006 + SNOMEDCT_2010_1_31:195208004 + SNOMEDCT_2010_1_31:230690007 + SNOMEDCT_2010_1_31:266312006 + SNOMEDCT_2010_1_31:266315008 + SNOMEDCT_2010_1_31:270883006 + SNOMEDCT_2010_1_31:313267000 + SNOMEDCT_2010_1_31:82797006 + UMLS_CUI:C0038454 + CVA (cerebral vascular accident) + CVA - Cerebrovascular accident unspecified + Cerebrovascular accident (disorder) + Cerebrovascular accident (disorder) [Ambiguous] + disease_ontology + Stroke + DOID:3455 + OMIM mapping confirmed by DO. [SN]. + cerebrovascular accident + + + + + + + + + + MSH:D014854 + NCI:C84807 + SNOMEDCT_2010_1_31:195193009 + SNOMEDCT_2010_1_31:78569004 + UMLS_CUI:C0043019 + Posterior inferior cerebellar artery syndrome (disorder) + Wallenberg syndrome + disease_ontology + DOID:3522 + lateral medullary syndrome + + + + + + + + + + MSH:D020526 + SNOMEDCT_2010_1_31:195191006 + SNOMEDCT_2010_1_31:195192004 + SNOMEDCT_2010_1_31:230697005 + SNOMEDCT_2010_1_31:95457000 + UMLS_CUI:C0521542 + Brainstem infarction + Brainstem infarction NOS + Brainstem infarction NOS (disorder) + brain stem infarction (disorder) + disease_ontology + DOID:3523 + brain stem infarction + + + + + + + + + + MSH:D020244 + UMLS_CUI:C0740392 + disease_ontology + DOID:3525 + middle cerebral artery infarction + + + + + + + + + + MSH:D002544 + NCI:C50486 + SNOMEDCT_2010_1_31:155405006 + SNOMEDCT_2010_1_31:195188006 + SNOMEDCT_2010_1_31:195191006 + SNOMEDCT_2010_1_31:20059004 + SNOMEDCT_2010_1_31:266256009 + SNOMEDCT_2010_1_31:266315008 + SNOMEDCT_2010_1_31:432504007 + UMLS_CUI:C0007785 + CVA - Cerebral infarction + Cerebral infarct + Cerebral infarction + Cerebral infarction NOS + Cerebral infarction NOS (disorder) + disease_ontology + DOID:3526 + cerebral infarction + + + + + + + + + + MSH:D002539 + UMLS_CUI:C0007774 + disease_ontology + DOID:3527 + cerebral arterial disease + + + + + + + + + + MSH:D020243 + UMLS_CUI:C0751843 + disease_ontology + DOID:3528 + anterior cerebral artery infarction @@ -7279,6 +16532,7 @@ + @@ -7286,6 +16540,12 @@ A thrombosis that occurs in a dural venous sinus. + + MSH:D012851 + UMLS_CUI:C0037198 + disease_ontology + DOID:3572 + intracranial sinus thrombosis @@ -7301,6 +16561,71 @@ A thrombosis that occurs in a transverse sinus. + + MSH:D020227 + SNOMEDCT_2010_1_31:192761004 + SNOMEDCT_2010_1_31:21258007 + UMLS_CUI:C0270639 + Thrombosis of lateral venous sinus (disorder) + Thrombosis transverse sinus (disorder) + disease_ontology + DOID:3574 + lateral sinus thrombosis + + + + + + + + + A thrombosis that occurs in a cavernous sinus. + + MSH:D020226 + SNOMEDCT_2010_1_31:89980009 + UMLS_CUI:C0238454 + Thrombosis of cavernous venous sinus (disorder) + disease_ontology + DOID:3575 + cavernous sinus thrombosis + + + + + + + + + + MSH:D020225 + SNOMEDCT_2010_1_31:192760003 + SNOMEDCT_2010_1_31:70607008 + UMLS_CUI:C0338575 + Thrombosis of superior longitudinal sinus (disorder) + Thrombosis of superior sagittal sinus (disorder) + disease_ontology + DOID:3576 + sagittal sinus thrombosis + + + + + + + + + + MSH:D001014 + NCI:C26697 + SNOMEDCT_2010_1_31:155419006 + SNOMEDCT_2010_1_31:155424009 + SNOMEDCT_2010_1_31:195269009 + SNOMEDCT_2010_1_31:67362008 + UMLS_CUI:C0003486 + disease_ontology + DOID:3627 + aortic aneurysm + aortic aneurysm disease @@ -7309,6 +16634,33 @@ + + MSH:D007383 + SNOMEDCT_2010_1_31:155430009 + SNOMEDCT_2010_1_31:195312007 + SNOMEDCT_2010_1_31:63491006 + UMLS_CUI:C0021775 + Charcot's syndrome + Intermittent claudication + Intermittent claudication (disorder) + Intermittent claudication NOS + disease_ontology + DOID:3669 + intermittent claudication + + + + + + + + + + MSH:D020762 + UMLS_CUI:C0752132 + disease_ontology + DOID:3821 + posterior cerebral artery infarction @@ -7317,6 +16669,16 @@ + + + MSH:D012790 + SNOMEDCT_2010_1_31:24453002 + UMLS_CUI:C0037018 + Shwartzman phenomenon + Shwartzman reaction (function) + disease_ontology + DOID:3825 + Shwartzman phenomenon @@ -7353,6 +16715,23 @@ + + MSH:D014927 + NCI:C35132 + OMIM:194200 + SNOMEDCT_2010_1_31:155360000 + SNOMEDCT_2010_1_31:251115003 + SNOMEDCT_2010_1_31:266304003 + SNOMEDCT_2010_1_31:74390002 + UMLS_CUI:C0043202 + Wolff Parkinson White syndrome + Wolff-Park-White syndr. + Wolff-Parkinson-White pattern (disorder) + Wolff-Parkinson-White pattern (finding) + Wolff-Parkinson-White syndrome + disease_ontology + DOID:384 + Wolff-Parkinson-White syndrome @@ -7398,6 +16777,46 @@ + + DOID:1146 + MSH:D013924 + NCI:C3410 + SNOMEDCT_2010_1_31:195401008 + SNOMEDCT_2010_1_31:195433004 + SNOMEDCT_2010_1_31:266266001 + SNOMEDCT_2010_1_31:40283005 + SNOMEDCT_2010_1_31:64156001 + UMLS_CUI:C0040046 + UMLS_CUI:C0265057 + Phlebitis and thrombophlebitis of superficial vessels of lower extremities + Superficial thrombophlebitis of leg + Superficial thrombophlebitis of leg (disorder) + Thrombophlebitis (disorder) + Thrombophlebitis NOS (disorder) + Thrombophlebitis of a superficial leg vein NOS (disorder) + Thrombophlebitis of superficial veins of lower extremity (disorder) + thrombophlebitis + disease_ontology + DOID:3875 + thrombophlebitis + + + + + + + + + + MSH:D000868 + SNOMEDCT_2010_1_31:157669006 + SNOMEDCT_2010_1_31:212379008 + SNOMEDCT_2010_1_31:269407005 + UMLS_CUI:C0003152 + Anterior compartment syndrome + disease_ontology + DOID:3933 + anterior compartment syndrome @@ -7417,6 +16836,19 @@ A myocarditis with an acute disease course. + + ICD9CM:422 + ICD9CM:422.90 + NCI:C35206 + SNOMEDCT_2010_1_31:155336004 + SNOMEDCT_2010_1_31:194953001 + SNOMEDCT_2010_1_31:194961006 + SNOMEDCT_2010_1_31:195569005 + SNOMEDCT_2010_1_31:46701001 + UMLS_CUI:C0155686 + disease_ontology + DOID:3951 + acute myocarditis @@ -7424,6 +16856,7 @@ + @@ -7440,6 +16873,15 @@ + A restrictive cardiomyopathy that affects the endocardium and occurs with white blood cell proliferation, specifically of eosinophils. + + NCI:C27044 + SNOMEDCT_2010_1_31:33258008 + UMLS_CUI:C0264834 + Eosinophilic Endomyocardial disease + disease_ontology + DOID:396 + Loeffler endocarditis @@ -7469,6 +16911,42 @@ A cardiomyopathy (2008) characterized by increased stiffness of the left ventricular myocardium and decreased compliance of the left ventricle (which is restricted from stretching and filling with blood properly), in the absence of dilated cardiomyopathy and hypertrophic cardiomyopathy. + + MSH:D002313 + NCI:C62798 + SNOMEDCT_2010_1_31:389996009 + SNOMEDCT_2010_1_31:415295002 + SNOMEDCT_2010_1_31:90828009 + UMLS_CUI:C0007196 + Cardiomyopathy, constrictive + Restrictive cardiomyopathy + Restrictive cardiomyopathy (disorder) + primary restrictive cardiomyopathy (disorder) + disease_ontology + DOID:397 + restrictive cardiomyopathy + + + + + + + + + + + MSH:C536366 + NCI:C3926 + SNOMEDCT_2010_1_31:11790000 + SNOMEDCT_2010_1_31:195382003 + SNOMEDCT_2010_1_31:49465005 + UMLS_CUI:C0263637 + Angioma Serpiginosum + Angioma serpiginosum (disorder) + Angioma serpiginosum of skin + disease_ontology + DOID:4028 + angioma serpiginosum @@ -7518,6 +16996,19 @@ A disease in which some disorder of a tricuspid valve prevents it from opening properly during right ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve. + A heart valve disease which results in the narrowing of the orifice of the tricuspid valve of the heart. This causes increased resistance to blood flow through the valve. It is almost always caused by rheumatic fever and is generally accompanied by mitral stenosis. Rare other causes include carcinoid syndrome, endocarditis, endomyocardial fibrosis, lupus erythematosus, right atrial myxoma and congenital tricuspid atresia. + + MSH:D014264 + NCI:C50783 + SNOMEDCT_2010_1_31:155346002 + SNOMEDCT_2010_1_31:266296006 + SNOMEDCT_2010_1_31:49915006 + UMLS_CUI:C0040963 + Tricuspid stenosis + Tricuspid valve stenosis (disorder) + disease_ontology + DOID:4078 + tricuspid valve stenosis @@ -7555,6 +17046,17 @@ A disease affecting a valve of the heart. + Heart valve disease is a heart disease described as any disease process involving one or more of the valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right). Valve problems may be congenital (inborn) or acquired (due to another cause later in life). + + MSH:D006349 + NCI:C45525 + SNOMEDCT_2010_1_31:195013005 + SNOMEDCT_2010_1_31:368009 + UMLS_CUI:C0018824 + Valvular heart disease (disorder) + disease_ontology + DOID:4079 + heart valve disease @@ -7604,6 +17106,22 @@ A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve. + A heart valve disease where the heart's tricuspid valve fails to close properly during systole. As a result, with each heart beat, blood is pumped out from the right side of the heart in the opposite direction to normal. + + MSH:D014262 + NCI:C50842 + NCI:C50843 + SNOMEDCT_2010_1_31:111287006 + SNOMEDCT_2010_1_31:155347006 + SNOMEDCT_2010_1_31:251009000 + SNOMEDCT_2010_1_31:266298007 + UMLS_CUI:C0040961 + Tricuspid incompetence + Tricuspid regurgitation + Tricuspid valve regurgitation (disorder) + disease_ontology + DOID:4080 + tricuspid valve insufficiency @@ -7619,6 +17137,31 @@ A thrombosis occurring in the brain. + + DOID:12751 + ICD9CM:434.0 + MSH:D020767 + SNOMEDCT_2010_1_31:155401002 + UMLS_CUI:C0079102 + UMLS_CUI:C0752143 + cerebral thrombosis + disease_ontology + DOID:4193 + intracranial thrombosis + + + + + + + + + + MSH:D023903 + UMLS_CUI:C0948480 + disease_ontology + DOID:4247 + coronary restenosis @@ -7634,6 +17177,15 @@ A disorder of atheromous plaques in a coronary artery. + + MSH:D023921 + NCI:C80427 + SNOMEDCT_2010_1_31:233970002 + UMLS_CUI:C0242231 + Coronary artery stenosis (disorder) + disease_ontology + DOID:4248 + coronary stenosis @@ -7658,6 +17210,20 @@ + + DOID:1957 + DOID:1958 + ICD9CM:434.1 + MSH:D020766 + SNOMEDCT_2010_1_31:155402009 + SNOMEDCT_2010_1_31:75543006 + UMLS_CUI:C0007780 + UMLS_CUI:C0752140 + Cerebral embolism with cerebral infarction + cerebral embolism + disease_ontology + DOID:4372 + intracranial embolism @@ -7667,6 +17233,23 @@ A bacterial endocarditis characterized by a slow process of infection. + + MSH:D004698 + NCI:C34583 + SNOMEDCT_2010_1_31:155334001 + SNOMEDCT_2010_1_31:194923008 + SNOMEDCT_2010_1_31:50194006 + SNOMEDCT_2010_1_31:73774007 + UMLS_CUI:C0014122 + Endocarditis lenta + SBE - Subacute bacterial endocarditis + Subacute bacterial endocarditis + Subacute bacterial endocarditis (disorder) + Subacute endocarditis, lenta + disease_ontology + DOID:4562 + + subacute bacterial endocarditis @@ -7675,6 +17258,44 @@ + + NCI:C4905 + SNOMEDCT_2010_1_31:189195009 + SNOMEDCT_2010_1_31:254773009 + SNOMEDCT_2010_1_31:93471006 + UMLS_CUI:C0687140 + Angioma of the skin + Angiomatous naevus of skin + hemangioma of skin (disorder) + skin hemangioma + disease_ontology + DOID:471 + skin hemangioma + + + + + + + + + + MSH:D006392 + NCI:C3086 + SNOMEDCT_2010_1_31:157014007 + SNOMEDCT_2010_1_31:189192007 + SNOMEDCT_2010_1_31:254781005 + SNOMEDCT_2010_1_31:33377007 + SNOMEDCT_2010_1_31:416824008 + SNOMEDCT_2010_1_31:56975005 + SNOMEDCT_2010_1_31:67668002 + UMLS_CUI:C0018920 + Cavernoma + Cavernous haemangioma (disorder) + Cavernous hemangioma (morphologic abnormality) + disease_ontology + DOID:483 + cavernous hemangioma @@ -7683,6 +17304,61 @@ + + MSH:D020141 + SNOMEDCT_2010_1_31:21112004 + UMLS_CUI:C0600502 + disease_ontology + DOID:484 + vascular hemostatic disease + + + + + + + + + + MSH:D001162 + SNOMEDCT_2010_1_31:361133006 + SNOMEDCT_2010_1_31:60625000 + UMLS_CUI:C0003851 + Arteriosclerosis obliterans (disorder) + Arteriosclerosis obliterans (disorder) [Ambiguous] + disease_ontology + DOID:5160 + arteriosclerosis obliterans + + + + + + + + + + UMLS_CUI:C0544830 + disease_ontology + DOID:5161 + Monckeberg arteriosclerosis + + + + + + + + + + MSH:D050379 + NCI:C35543 + SNOMEDCT_2010_1_31:17941002 + UMLS_CUI:C0878486 + Arteriolosclerosis (morphologic abnormality) + disease_ontology + DOID:5162 + arteriolosclerosis @@ -7712,6 +17388,16 @@ A disease characterized by an inflammation of the aorta. + + MSH:D001025 + SNOMEDCT_2010_1_31:195368003 + SNOMEDCT_2010_1_31:70933002 + UMLS_CUI:C0003509 + Aortitis (disorder) + Aortitis NOS + disease_ontology + DOID:519 + aortitis @@ -7749,6 +17435,15 @@ A disease affecting the aorta. + + MSH:D001018 + SNOMEDCT_2010_1_31:47040006 + UMLS_CUI:C0003493 + aortic disorder + disorder of the aorta (disorder) + disease_ontology + DOID:520 + aortic disease @@ -7782,6 +17477,12 @@ A disease characterized by the displacement of a degenerated aortic valve leaflet into the left ventricle during diastole. + + MSH:D001023 + UMLS_CUI:C0003505 + disease_ontology + DOID:5232 + aortic valve prolapse @@ -7789,6 +17490,7 @@ + @@ -7805,6 +17507,45 @@ + + MSH:D020293 + NCI:C84622 + UMLS_CUI:C0751878 + disease_ontology + DOID:525 + central nervous system vasculitis + + + + + + + + + + NCI:C7739 + UMLS_CUI:C0238814 + disease_ontology + DOID:5393 + brain angioma + + + + + + + + + Aortic incompetence is a aortic valve disease where leakage of blood from the aorta back into the left ventricle during diastole because of failure of an aortic valve to close properly. + + ICD9CM:396.3 + SNOMEDCT_2010_1_31:194736003 + SNOMEDCT_2010_1_31:59464004 + UMLS_CUI:C0264774 + disease_ontology + Corrigan's disease + DOID:54 + aortic incompetence @@ -7813,6 +17554,38 @@ + + MSH:D011668 + NCI:C85039 + OMIM:265450 + SNOMEDCT_2010_1_31:89420002 + UMLS_CUI:C0034091 + pulmonary veno-occlusive disease (disorder) + disease_ontology + DOID:5453 + OMIM mapping confirmed by DO. [SN]. + pulmonary venoocclusive disease + + + + + + + + + An aortic valve insufficiency due to rheumatic fever. + + ICD9CM:395.1 + SNOMEDCT_2010_1_31:155283004 + SNOMEDCT_2010_1_31:78031003 + UMLS_CUI:C0155568 + Rheumatic aortic insufficiency + Rheumatic aortic regurgitation + Rheumatic aortic regurgitation (disorder) + Rheumatic aortic valve regurgitation + disease_ontology + DOID:55 + rheumatic aortic valve insufficiency @@ -7846,6 +17619,14 @@ A disease characterized by the displacement of a degenerated tricuspid valve leaflet into the right atrium during systole. + + MSH:D014263 + SNOMEDCT_2010_1_31:253383003 + UMLS_CUI:C0040962 + Tricuspid valve prolapse (disorder) + disease_ontology + DOID:5644 + tricuspid valve prolapse @@ -7895,6 +17676,40 @@ A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve. + Aortic valve insufficiency is a aortic valve disease where leaking of the aortic valve of the heart causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. Aortic insufficiency can be due to abnormalities of either the aortic valve or the aortic root (the beginning of the aorta). + + MSH:D001022 + NCI:C50861 + NCI:C51223 + SNOMEDCT_2010_1_31:60234000 + UMLS_CUI:C0003504 + Aortic valve regurgitation (disorder) + aortic insufficiency + aortic regurgitation + disease_ontology + DOID:57 + aortic valve insufficiency + + + + + + + + + + ICD9CM:397.1 + SNOMEDCT_2010_1_31:18687009 + SNOMEDCT_2010_1_31:194747005 + SNOMEDCT_2010_1_31:266283005 + UMLS_CUI:C0155579 + Rheumatic disease of pulmonary valve + Rheumatic disease of pulmonary valve (disorder) + Rheumatic pulmonary incompetence + Rheumatic pulmonary valve disease NOS (disorder) + disease_ontology + DOID:5748 + rheumatic pulmonary valve disease @@ -7932,6 +17747,52 @@ A disease affecting the pulmonary valve of the heart. + + ICD9CM:424.3 + NCI:C78579 + SNOMEDCT_2010_1_31:195001000 + SNOMEDCT_2010_1_31:76267008 + UMLS_CUI:C0034087 + pulmonary valve disorder + disease_ontology + DOID:5749 + pulmonary valve disease + + + + + + + + + + ICD9CM:394.1 + SNOMEDCT_2010_1_31:155278007 + SNOMEDCT_2010_1_31:155279004 + SNOMEDCT_2010_1_31:266279005 + SNOMEDCT_2010_1_31:31085000 + UMLS_CUI:C0155563 + Rheumatic mitral insufficiency + Rheumatic mitral regurgitation + Rheumatic mitral regurgitation (disorder) + Rheumatic mitral valve regurgitation + disease_ontology + DOID:58 + rheumatic mitral valve incompetence + + + + + + + + + + MSH:D021922 + UMLS_CUI:C0012628 + disease_ontology + DOID:5804 + discrete subaortic stenosis @@ -7989,6 +17850,27 @@ This refers to a narrowing of the section of the left ventricle below the aortic valve; therefore, this was not classified as an aortic valve stenosis in CVDO. + + MSH:D001020 + NCI:C85172 + UMLS_CUI:C0003500 + disease_ontology + DOID:5805 + subvalvular aortic stenosis + + + + + + + + + + NCI:C36068 + UMLS_CUI:C1142433 + disease_ontology + DOID:5843 + posteroinferior myocardial infarction @@ -8024,6 +17906,218 @@ An infarction occurring in the myocardium. + + MSH:D009203 + NCI:C27996 + SNOMEDCT_2010_1_31:155304006 + SNOMEDCT_2010_1_31:194796000 + SNOMEDCT_2010_1_31:22298006 + SNOMEDCT_2010_1_31:233824008 + SNOMEDCT_2010_1_31:266288001 + SNOMEDCT_2010_1_31:66514008 + UMLS_CUI:C0027051 + Attack - heart + MI - Myocardial infarction + Myocardial Infarct + Myocardial Infarctions + Myocardial infarct + Myocardial infarction + Myocardial infarction (disorder) + Myocardial infarction NOS + heart attack + disease_ontology + DOID:5844 + myocardial infarction + + + + + + + + + + MSH:D056988 + NCI:C35303 + UMLS_CUI:C0262564 + disease_ontology + DOID:5845 + anterolateral myocardial infarction + + + + + + + + + + NCI:C35519 + UMLS_CUI:C0746727 + disease_ontology + DOID:5846 + septal myocardial infarction + + + + + + + + + + NCI:C35399 + SNOMEDCT_2010_1_31:194800006 + UMLS_CUI:C0340319 + Posterior myocardial infarction NOS (disorder) + disease_ontology + DOID:5847 + posterior myocardial infarction + + + + + + + + + + NCI:C36073 + UMLS_CUI:C1168331 + disease_ontology + DOID:5848 + apical myocardial infarction + + + + + + + + + + NCI:C35305 + UMLS_CUI:C0262568 + disease_ontology + DOID:5849 + subendocardial myocardial infarction + + + + + + + + + + MSH:D056989 + NCI:C35398 + NCI:C71070 + SNOMEDCT_2010_1_31:194804002 + UMLS_CUI:C0340305 + Inferior myocardial infarction NOS (disorder) + disease_ontology + DOID:5850 + inferior myocardial infarction + + + + + + + + + + NCI:C35672 + UMLS_CUI:C1112662 + disease_ontology + DOID:5851 + posterolateral myocardial infarction + + + + + + + + + + NCI:C35673 + UMLS_CUI:C1112770 + disease_ontology + DOID:5852 + inferolateral myocardial infarct + + + + + + + + + + NCI:C35586 + SNOMEDCT_2010_1_31:194801005 + UMLS_CUI:C0340312 + Lateral myocardial infarction NOS (disorder) + disease_ontology + DOID:5853 + lateral myocardial infarction + + + + + + + + + + NCI:C35400 + SNOMEDCT_2010_1_31:194796000 + SNOMEDCT_2010_1_31:233843008 + UMLS_CUI:C0340324 + Silent myocardial infarction + Silent myocardial infarction (disorder) + disease_ontology + DOID:5854 + silent myocardial infarction + + + + + + + + + + MSH:D056988 + NCI:C35304 + UMLS_CUI:C0262565 + disease_ontology + DOID:5855 + anteroseptal myocardial infarction + + + + + + + + + + DOID:10961 + DOID:1547 + ICD9CM:433 + ICD9CM:433.3 + ICD9CM:433.9 + UMLS_CUI:C0155722 + UMLS_CUI:C0155725 + UMLS_CUI:C0155727 + disease_ontology + Occlusion and stenosis of multiple and bilateral precerebral arteries + occlusion and stenosis of precerebral artery + DOID:5976 + occlusion precerebral artery @@ -8053,6 +18147,33 @@ A disease characterized by the inability of the heart to pump a sufficient amount of blood throughout the body. + A heart disease that is characterized by any structural or functional cardiacdisorder that impairs the ability of the heart to fill with or pump a sufficient amount ofblood throughout the body. + + DOID:395 + ICD9CM:428 + ICD9CM:428.0 + ICD9CM:428.9 + MSH:D006333 + NCI:C3080 + NCI:C50577 + SNOMEDCT_2010_1_31:155374007 + SNOMEDCT_2010_1_31:155375008 + SNOMEDCT_2010_1_31:155377000 + SNOMEDCT_2010_1_31:195108009 + SNOMEDCT_2010_1_31:195117009 + SNOMEDCT_2010_1_31:266248006 + SNOMEDCT_2010_1_31:266308000 + SNOMEDCT_2010_1_31:42343007 + SNOMEDCT_2010_1_31:84114007 + UMLS_CUI:C0018801 + UMLS_CUI:C0018802 + CHF + Cardiac Failure Congestive + Congestive heart disease + Weak heart + disease_ontology + DOID:6000 + congestive heart failure @@ -8090,6 +18211,22 @@ A disease affecting the mitral valve of the heart. + + DOID:59 + ICD9CM:424.0 + NCI:C78446 + SNOMEDCT_2010_1_31:11851006 + SNOMEDCT_2010_1_31:194729004 + SNOMEDCT_2010_1_31:194982000 + UMLS_CUI:C0026265 + Mitral and aortic valve disease NOS (disorder) + Mitral and aortic valve disease, unspecified + disease of mitral and aortic valves + disease of mitral and aortic valves (disorder) + mitral valve disease + disease_ontology + DOID:61 + mitral valve disease @@ -8127,6 +18264,13 @@ A disease affecting the aortic valve of the heart. + + DOID:56 + ICD9CM:395.9 + UMLS_CUI:C0155570 + disease_ontology + DOID:62 + aortic valve disease @@ -8145,6 +18289,17 @@ + + A disease that has_material_basis_in genetic variations in the human genome. + + MSH:D030342 + NCI:C3101 + SNOMEDCT_2010_1_31:264530000 + SNOMEDCT_2010_1_31:32895009 + UMLS_CUI:C0019247 + disease_ontology + DOID:630 + genetic disease @@ -8194,13 +18349,54 @@ A disease in which some disorder of a pulmonary valve prevents it from opening properly during right ventricular systole, occasioning disturbance in the anterograd blood flow through the valve. + + MSH:D011666 + SNOMEDCT_2010_1_31:56786000 + UMLS_CUI:C0034089 + Pulmonic stenosis NOS + Pulmonic valve stenosis (disorder) + pulmonary stenosis NOS + pulmonary stenosis, cause unspecified (disorder) + pulmonary valve stenosis + disease_ontology + DOID:6420 + pulmonary valve stenosis - + + + + MSH:D006976 + NCI:C3120 + SNOMEDCT_2010_1_31:155328008 + SNOMEDCT_2010_1_31:266293003 + SNOMEDCT_2010_1_31:70995007 + UMLS_CUI:C0020542 + pulmonary hypertension + pulmonary hypertension (disorder) + disease_ontology + DOID:6432 + pulmonary hypertension + + + + + + + + + + NCI:C5433 + UMLS_CUI:C0877388 + hemangioma of Cerebrum + disease_ontology + DOID:6621 + cerebral angioma + @@ -8208,6 +18404,15 @@ + + + MSH:D020759 + SNOMEDCT_2010_1_31:2972007 + UMLS_CUI:C0221069 + Anterior spinal artery occlusion syndrome (disorder) + disease_ontology + DOID:6712 + anterior spinal artery syndrome @@ -8216,6 +18421,24 @@ + + DOID:12214 + DOID:8231 + ICD9CM:430-438.99 + ICD9CM:437.9 + MSH:D002561 + NCI:C2938 + SNOMEDCT_2010_1_31:155388006 + SNOMEDCT_2010_1_31:155412002 + SNOMEDCT_2010_1_31:195249004 + SNOMEDCT_2010_1_31:195595007 + SNOMEDCT_2010_1_31:266312006 + SNOMEDCT_2010_1_31:62914000 + UMLS_CUI:C0007820 + cerebrovascular disorder + disease_ontology + DOID:6713 + cerebrovascular disease @@ -8224,6 +18447,157 @@ + + ICD9CM:958.90 + MSH:D003161 + SNOMEDCT_2010_1_31:111245009 + SNOMEDCT_2010_1_31:212379008 + SNOMEDCT_2010_1_31:45781009 + UMLS_CUI:C0009492 + Compartment syndrome + Compartment syndrome (disorder) + Compartmental syndrome, NOS + disease_ontology + DOID:682 + compartment syndrome + + + + + + + + + + ICD9CM:708.3 + SNOMEDCT_2010_1_31:123093003 + SNOMEDCT_2010_1_31:156430003 + SNOMEDCT_2010_1_31:201263000 + SNOMEDCT_2010_1_31:201265007 + SNOMEDCT_2010_1_31:238685008 + SNOMEDCT_2010_1_31:247473009 + SNOMEDCT_2010_1_31:270885004 + SNOMEDCT_2010_1_31:402410006 + SNOMEDCT_2010_1_31:402601007 + SNOMEDCT_2010_1_31:7632005 + UMLS_CUI:C0343065 + Dermatographic urticaria + Dermographism + Physical urticaria + disease_ontology + DOID:743 + dermatographia + + + + + + + + + + ICD9CM:441.5 + MSH:D001019 + NCI:C27198 + SNOMEDCT_2010_1_31:155423003 + SNOMEDCT_2010_1_31:195264004 + SNOMEDCT_2010_1_31:195615002 + SNOMEDCT_2010_1_31:73067008 + UMLS_CUI:C0741160 + Aortic aneurysm of unspecified site, ruptured + Aortic aneurysm of unspecified site, ruptured (disorder) + Ruptured Aortic Aneurysm + Ruptured aortic aneurysm (disorder) + Ruptured aortic aneurysm NOS + Ruptured aortic aneurysm NOS (disorder) + disease_ontology + DOID:7682 + ruptured aortic aneurysm + ruptured aortic aneurysm disease + + + + + + + + + + ICD9CM:441.0 + NCI:C26751 + SNOMEDCT_2010_1_31:155420000 + SNOMEDCT_2010_1_31:308546005 + SNOMEDCT_2010_1_31:67076004 + UMLS_CUI:C0012736 + disease_ontology + DOID:7683 + dissecting aortic aneurysm + dissecting aortic aneurysm disease + + + + + + + + + + ICD9CM:441.3 + NCI:C27046 + SNOMEDCT_2010_1_31:14336007 + UMLS_CUI:C0265012 + Ruptured abdominal Aortic Aneurysm + Ruptured abdominal aortic aneurysm (disorder) + abdominal aortic aneurysm, ruptured + disease_ontology + DOID:7692 + ruptured abdominal aortic aneurysm + ruptured abdominal aortic aneurysm disease + + + + + + + + + + MSH:D017544 + NCI:C27000 + OMIM:100070 + SNOMEDCT_2010_1_31:155422008 + SNOMEDCT_2010_1_31:233985008 + UMLS_CUI:C0162871 + AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1 + abdominal Aortic Aneurysm + abdominal aortic aneurysm + abdominal aortic aneurysm (disorder) + disease_ontology + DOID:7693 + abdominal aortic aneurysm + abdominal aortic aneurysm disease + + + + + + + + + + ICD9CM:441.1 + NCI:C27299 + SNOMEDCT_2010_1_31:195258006 + SNOMEDCT_2010_1_31:34365005 + UMLS_CUI:C0265010 + Ruptured Thoracic Aneurysm + Ruptured thoracic aortic aneurysm (disorder) + Thoracic aortic aneurysm which has ruptured (disorder) + Thoracic aortic aneurysm, ruptured + disease_ontology + DOID:7703 + ruptured thoracic aortic aneurysm + ruptured thoracic aortic aneurysm disease @@ -8232,6 +18606,58 @@ + + MSH:D014648 + NCI:C35114 + OMIM:192200 + SNOMEDCT_2010_1_31:128060009 + SNOMEDCT_2010_1_31:12856003 + SNOMEDCT_2010_1_31:155468006 + SNOMEDCT_2010_1_31:155482006 + SNOMEDCT_2010_1_31:234053000 + SNOMEDCT_2010_1_31:266331000 + SNOMEDCT_2010_1_31:276504003 + SNOMEDCT_2010_1_31:399989005 + UMLS_CUI:C0042345 + Varix (morphologic abnormality) + Venous ectasia + Venous varices (disorder) + varices + disease_ontology + DOID:799 + OMIM mapping confirmed by DO. [LS]. + varicose veins + + + + + + + + + + ICD9CM:433.10 + UMLS_CUI:C0375275 + Occlusion and stenosis of carotid artery + disease_ontology + DOID:807 + carotid artery occlusion + + + + + + + + + + NCI:C35786 + SNOMEDCT_2010_1_31:37925008 + UMLS_CUI:C0027060 + Interstitial myocarditis (disorder) + disease_ontology + DOID:817 + interstitial myocarditis @@ -8261,6 +18687,123 @@ A disease characterized by an inflammation of the myocardium. + + ICD9CM:429.0 + MSH:D009205 + NCI:C34831 + SNOMEDCT_2010_1_31:155380004 + SNOMEDCT_2010_1_31:195119007 + SNOMEDCT_2010_1_31:251060004 + SNOMEDCT_2010_1_31:50920009 + UMLS_CUI:C0027059 + Myocardial inflammation (finding) + Myocarditis (disorder) + Myocarditis NOS + Myocarditis NOS (disorder) + Myocarditis, unspecified + myocarditis + disease_ontology + DOID:820 + myocarditis + + + + + + + + + A myocarditis caused by rheumatic fever. + + DOID:14025 + DOID:14036 + ICD9CM:391.9 + NCI:C34985 + SNOMEDCT_2010_1_31:155270000 + SNOMEDCT_2010_1_31:194713007 + SNOMEDCT_2010_1_31:194750008 + SNOMEDCT_2010_1_31:195136004 + SNOMEDCT_2010_1_31:266285003 + SNOMEDCT_2010_1_31:312591002 + SNOMEDCT_2010_1_31:367538001 + SNOMEDCT_2010_1_31:4536006 + SNOMEDCT_2010_1_31:8805001 + UMLS_CUI:C0035440 + UMLS_CUI:C0489959 + Rheumatic degeneration of myocardium + Rheumatic fever with myocarditis + Rheumatic myocarditis + Rheumatic myocarditis (disorder) + Rheumatoid myocarditis (disorder) + active rheumatic fever with myocarditis + acute Rheumatic Myocarditis + acute rheumatic carditis + acute rheumatic myocarditis + acute rheumatic myocarditis (disorder) + acute rheumatic myocarditis (disorder) [Ambiguous] + disease_ontology + DOID:8481 + + rheumatic myocarditis + + + + + + + + + + ICD9CM:362.34 + NCI:C35193 + SNOMEDCT_2010_1_31:193377008 + SNOMEDCT_2010_1_31:87224000 + UMLS_CUI:C0154840 + Retinal transient arterial occlusion NOS (disorder) + Transient arterial retinal occlusion (disorder) + Transient retinal arterial occlusion + disease_ontology + DOID:8482 + transient retinal arterial occlusion + + + + + + + + + + + MSH:D015356 + NCI:C34978 + SNOMEDCT_2010_1_31:232035005 + UMLS_CUI:C0035302 + Retinal artery occlusion (disorder) + disease_ontology + DOID:8483 + retinal artery occlusion + + + + + + + + + + ICD9CM:673 + SNOMEDCT_2010_1_31:156273009 + SNOMEDCT_2010_1_31:200284000 + SNOMEDCT_2010_1_31:200320009 + SNOMEDCT_2010_1_31:200321008 + SNOMEDCT_2010_1_31:200326003 + SNOMEDCT_2010_1_31:237341004 + SNOMEDCT_2010_1_31:50286006 + UMLS_CUI:C0157540 + disease_ontology + DOID:8512 + puerperal pulmonary embolism @@ -8292,6 +18835,18 @@ A cor pulmonale that has an acute disease course during which the right ventricle becomes dilated. 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO. + + ICD9CM:415 + SNOMEDCT_2010_1_31:155324005 + SNOMEDCT_2010_1_31:194880009 + SNOMEDCT_2010_1_31:194884000 + SNOMEDCT_2010_1_31:67189007 + UMLS_CUI:C0155671 + acute pulmonary heart disease (disorder) + acute pulmonary heart disease NOS (disorder) + disease_ontology + DOID:8514 + acute pulmonary heart disease @@ -8334,6 +18889,22 @@ A disease characterized by a dilatation or hypertrophy of the myocardium of right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs, involving a failure of the right side of the heart. Although the 1995 classification of cardiomyopathies did not include cor pulmonale, it should have included it, given the definition of cardiomyopathy it adopted. + A congestive heart failure that involves a failure of the right side of the heart and is characterized by an enlargement of the right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs. + + MSH:D011660 + SNOMEDCT_2010_1_31:155323004 + SNOMEDCT_2010_1_31:155329000 + SNOMEDCT_2010_1_31:194879006 + SNOMEDCT_2010_1_31:266294009 + SNOMEDCT_2010_1_31:274096000 + SNOMEDCT_2010_1_31:286952009 + SNOMEDCT_2010_1_31:83291003 + UMLS_CUI:C0034072 + cardiopulmonary disease + pulmonary heart disease + disease_ontology + DOID:8515 + cor pulmonale @@ -8355,6 +18926,12 @@ A pathological process consisting in a pulmonary embolism and an infarction that follows. + + ICD9CM:415.1 + UMLS_CUI:C0034066 + disease_ontology + DOID:8516 + pulmonary embolism and infarction @@ -8384,6 +18961,16 @@ 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO. + + ICD9CM:415.0 + SNOMEDCT_2010_1_31:155325006 + SNOMEDCT_2010_1_31:194881008 + SNOMEDCT_2010_1_31:49584005 + UMLS_CUI:C0155672 + acute cor pulmonale (disorder) + disease_ontology + DOID:8517 + acute cor pulmonale @@ -8413,6 +19000,18 @@ A disease characterized by an inflammation of a vein. + + MSH:D010689 + NCI:C38003 + SNOMEDCT_2010_1_31:195432009 + SNOMEDCT_2010_1_31:61599003 + UMLS_CUI:C0031542 + Phlebitis (disorder) + Phlebitis NOS (disorder) + phlebitis + disease_ontology + DOID:864 + phlebitis @@ -8442,6 +19041,19 @@ A disease characterized by an inflammation of a blood vessel. + A vascular disease that is an inflammatory destruction of blood vessels. + + MSH:D014657 + NCI:C26912 + SNOMEDCT_2010_1_31:195375002 + SNOMEDCT_2010_1_31:266325003 + SNOMEDCT_2010_1_31:31996006 + SNOMEDCT_2010_1_31:393589007 + UMLS_CUI:C0042384 + Angiitis + disease_ontology + DOID:865 + vasculitis @@ -8478,6 +19090,13 @@ + + ICD9CM:453 + SNOMEDCT_2010_1_31:195435006 + UMLS_CUI:C0155774 + disease_ontology + DOID:866 + vein disease @@ -8486,6 +19105,26 @@ + A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain. + + DOID:13915 + MSH:D015161 + NCI:C34522 + SNOMEDCT_2010_1_31:154850006 + SNOMEDCT_2010_1_31:191462009 + SNOMEDCT_2010_1_31:192165000 + SNOMEDCT_2010_1_31:192167008 + SNOMEDCT_2010_1_31:192171006 + SNOMEDCT_2010_1_31:268613002 + SNOMEDCT_2010_1_31:429998004 + SNOMEDCT_2010_1_31:56267009 + UMLS_CUI:C0011263 + UMLS_CUI:C0011269 + Multi Infarct Dementia + multifocal dementia + disease_ontology + DOID:8725 + vascular dementia @@ -8502,6 +19141,35 @@ A coronary heart disease with an acute disease course. DOID label 'intermediate coronary syndrome' was changed. + + ICD9CM:411.1 + MSH:D000789 + NCI:C66911 + SNOMEDCT_2010_1_31:155308009 + SNOMEDCT_2010_1_31:155313008 + SNOMEDCT_2010_1_31:155314002 + SNOMEDCT_2010_1_31:194814006 + SNOMEDCT_2010_1_31:194816008 + SNOMEDCT_2010_1_31:194817004 + SNOMEDCT_2010_1_31:194819001 + SNOMEDCT_2010_1_31:233818002 + SNOMEDCT_2010_1_31:233820004 + SNOMEDCT_2010_1_31:25106000 + SNOMEDCT_2010_1_31:4557003 + SNOMEDCT_2010_1_31:59021001 + SNOMEDCT_2010_1_31:64333001 + UMLS_CUI:C0002965 + (Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction) + Angina at rest + Anginal chest pain at rest + Impending infarction (disorder) + Preinfarction angina + Preinfarction angina (disorder) + Unstable angina + Worsening angina + disease_ontology + DOID:8805 + acute coronary syndrome @@ -8559,59 +19227,325 @@ DOID label 'pulmonary subvalvular stenosis' was changed for homogeneization with 'subvalvular aortic stenosis'. + + ICD9CM:746.83 + MSH:D011662 + NCI:C34961 + SNOMEDCT_2010_1_31:204370002 + SNOMEDCT_2010_1_31:3192005 + UMLS_CUI:C0034084 + Congenital Infundibular Stenosis + Infundibular pulmonic stenosis (disorder) + Infundibular pulmonic stenosis, congenital + Subvalvular pulmonic stenosis + pulmonary infundibular stenosis (disorder) pulmonary subvalvular stenosis + disease_ontology + DOID:8861 + subvalvular pulmonary stenosis + + + + + + + + + + MSH:D010382 + SNOMEDCT_2010_1_31:197366003 + SNOMEDCT_2010_1_31:240625009 + SNOMEDCT_2010_1_31:58008004 + UMLS_CUI:C0030781 + hepatic peliosis (disorder) + disease_ontology + DOID:914 + peliosis hepatis + + + + + + + + + + ICD9CM:443.82 + MSH:D004916 + NCI:C34593 + SNOMEDCT_2010_1_31:238777005 + SNOMEDCT_2010_1_31:37151006 + UMLS_CUI:C0014804 + Erythromelalgia (disorder) + disease_ontology + DOID:9240 + erythromelalgia + + + + + + + + + + ICD9CM:607.3 + MSH:D011317 + NCI:C85022 + SNOMEDCT_2010_1_31:155930001 + SNOMEDCT_2010_1_31:198027001 + SNOMEDCT_2010_1_31:4287008 + SNOMEDCT_2010_1_31:6273006 + UMLS_CUI:C0033117 + Mentulagra + Priapism (disorder) + disease_ontology + DOID:9286 + priapism + + + + + + + + + + ICD9CM:443.21 + SNOMEDCT_2010_1_31:230729006 + UMLS_CUI:C0338585 + Carotid artery dissection (disorder) + Dissection of carotid artery + disease_ontology + DOID:9348 + carotid artery dissection + + + + + + + + + + ICD9CM:410.60 + UMLS_CUI:C0155652 + disease_ontology + DOID:9407 + strictly posterior acute myocardial infarction + + + + + + + + + + ICD9CM:410 + ICD9CM:410.9 + ICD9CM:410.90 + NCI:C35204 + SNOMEDCT_2010_1_31:155304006 + SNOMEDCT_2010_1_31:194796000 + SNOMEDCT_2010_1_31:194811003 + SNOMEDCT_2010_1_31:266288001 + SNOMEDCT_2010_1_31:57054005 + UMLS_CUI:C0155626 + disease_ontology + DOID:9408 + acute myocardial infarction + + + + + + + + + + MSH:D019586 + NCI:C84791 + SNOMEDCT_2010_1_31:155052007 + SNOMEDCT_2010_1_31:267701004 + SNOMEDCT_2010_1_31:271719001 + SNOMEDCT_2010_1_31:28073009 + UMLS_CUI:C0151740 + Raised intracranial pressure + disease_ontology + DOID:9428 + intracranial hypertension + + + + + + + + + + + + + + + + + + + An embolism that occurs in a pulmonary artery. + + MSH:D011655 + NCI:C50713 + SNOMEDCT_2010_1_31:155326007 + SNOMEDCT_2010_1_31:194882001 + SNOMEDCT_2010_1_31:266292008 + SNOMEDCT_2010_1_31:59282003 + UMLS_CUI:C0034065 + pulmonary artery embolism + disease_ontology + DOID:9477 + pulmonary embolism + + + + + + + + + + ICD9CM:709.1 + MSH:D017445 + NCI:C35254 + SNOMEDCT_2010_1_31:11263005 + SNOMEDCT_2010_1_31:201306008 + SNOMEDCT_2010_1_31:267820009 + UMLS_CUI:C0162819 + disease_ontology + DOID:9540 + vascular skin disease + + + + + + + + + A congestive heart failure with impaired ejection fraction. + + ICD9CM:428.2 + ICD9CM:428.20 + MSH:D054143 + SNOMEDCT_2010_1_31:417996009 + UMLS_CUI:C1135191 + disease_ontology + DOID:9651 + systolic heart failure + + + + + + + + + + ICD9CM:422.93 + SNOMEDCT_2010_1_31:31993003 + UMLS_CUI:C0155691 + disease_ontology + DOID:9694 + toxic myocarditis - + - - + + + + ICD9CM:456.5 + SNOMEDCT_2010_1_31:17406005 + SNOMEDCT_2010_1_31:195481006 + SNOMEDCT_2010_1_31:266271008 + UMLS_CUI:C0155795 + disease_ontology + DOID:9742 + pelvic varices - + - - + + + + ICD9CM:455.4 + SNOMEDCT_2010_1_31:155474006 + SNOMEDCT_2010_1_31:157525008 + SNOMEDCT_2010_1_31:211490002 + SNOMEDCT_2010_1_31:26373009 + SNOMEDCT_2010_1_31:269372002 + UMLS_CUI:C0155784 + External thrombosed haemorrhoids + Thrombosed external hemorrhoids + disease_ontology + DOID:9745 + perianal hematoma - + - - - - - - - - - - - - - An embolism that occurs in a pulmonary artery. + + + + ICD9CM:455 + MSH:D006484 + NCI:C26792 + SNOMEDCT_2010_1_31:155469003 + SNOMEDCT_2010_1_31:155477004 + SNOMEDCT_2010_1_31:195472000 + SNOMEDCT_2010_1_31:70153002 + UMLS_CUI:C0019112 + disease_ontology + DOID:9746 + hemorrhoid - + - - + + + + ICD9CM:455.6 + SNOMEDCT_2010_1_31:82985000 + UMLS_CUI:C0041844 + disease_ontology + DOID:9749 + internal hemorrhoid - + - - A congestive heart failure with impaired ejection fraction. - + + + + MSH:D017682 + UMLS_CUI:C0206146 + disease_ontology + DOID:9767 + myocardial stunning + @@ -8625,15 +19559,57 @@ + + MSH:D006322 + SNOMEDCT_2010_1_31:155317009 + SNOMEDCT_2010_1_31:194847002 + SNOMEDCT_2010_1_31:65340007 + UMLS_CUI:C0018789 + cardiac aneurysm + disease_ontology + DOID:9768 + heart aneurysm - + + A congestive heart failure with preserved ejection fraction. - + + ICD9CM:428.3 + ICD9CM:428.30 + MSH:D054144 + SNOMEDCT_2010_1_31:418304008 + UMLS_CUI:C1135196 + disease_ontology + DOID:9775 + diastolic heart failure + + + + + + + + + + ICD9CM:446.0 + MSH:D010488 + NCI:C26847 + SNOMEDCT_2010_1_31:155441006 + SNOMEDCT_2010_1_31:155445002 + SNOMEDCT_2010_1_31:195347004 + SNOMEDCT_2010_1_31:266323005 + SNOMEDCT_2010_1_31:286960005 + SNOMEDCT_2010_1_31:66121003 + UMLS_CUI:C0031036 + disease_ontology + DOID:9810 + polyarteritis nodosa + @@ -8666,6 +19642,24 @@ A disease characterized by the displacement of a degenerated mitral valve leaflet into the left atrium during systole. + + MSH:D008945 + NCI:C50655 + OMIM:157700 + SNOMEDCT_2010_1_31:155386005 + SNOMEDCT_2010_1_31:194977007 + SNOMEDCT_2010_1_31:194980008 + SNOMEDCT_2010_1_31:409712001 + SNOMEDCT_2010_1_31:42069006 + SNOMEDCT_2010_1_31:45023003 + SNOMEDCT_2010_1_31:8074002 + UMLS_CUI:C0026267 + BARLOWS SYNDROME + Floppy mitral valve + disease_ontology + DOID:988 + OMIM mapping confirmed by DO. [SN]. + mitral valve prolapse @@ -8699,6 +19693,14 @@ A disease characterized by the displacement of a degenerated heart valve leaflet during systole. + + MSH:D016127 + SNOMEDCT_2010_1_31:398995000 + UMLS_CUI:C0079485 + Cardiac valve prolapse + disease_ontology + DOID:989 + heart valve prolapse @@ -8707,6 +19709,33 @@ + + ICD9CM:447.4 + SNOMEDCT_2010_1_31:9250002 + UMLS_CUI:C0152098 + Celiac artery compression syndrome + disease_ontology + DOID:9892 + Marable's syndrome + + + + + + + + + A dilated cardiomyopathy resulting from a pregnancy. It presents typically between the last month of pregnancy and up to six months postpartum. + + DOID:11697 + DOID:11980 + ICD9CM:674.5 + UMLS_CUI:C0877208 + antepartum peripartum cardiomyopathy + postpartum peripartum cardiomyopathy + disease_ontology + DOID:9997 + peripartum cardiomyopathy @@ -8714,12 +19743,18 @@ + + + Ventricular myocardium + fma + FMA:12151 + Myocardium of ventricle @@ -8727,153 +19762,549 @@ + + Region of wall of heart which consists of endocardium, myocardium and epicardium that surrounds the cavity of a cardiac chamber. + + Cardiac chamber wall + fma + FMA:13256 + Wall of cardiac chamber + + + + + + + + + Cardinal organ part which is bounded predominantly by bonafide boundaries. Examples: lobe of lung, osteon, acinus, submucosa, anterior leaflet of mitral valve, capsule of kidney, cortical bone, muscle fasciculus. + + fma + FMA:14065 + Organ component + + + + + + + + + Tissue which consists of cardiac myocytes surrounded by cardiac endomysium. Examples: Cardiac muscle tissue proper, conducting tissue of heart. + + fma + FMA:14068 + Cardiac muscle tissue - + + + Vascular tree, the organ parts of which are veins. Examples: There are only three canonical instances, systemic venous tree (organ), pulmonary venous tree (organ) and portal venous tree (organ). + + fma + FMA:14284 + Venous tree organ + - + + + + Common iliac venous tree + fma + FMA:14333 + Common iliac vein + - + + + + fma + FMA:18883 + External iliac vein + - + + + + fma + FMA:18884 + Internal iliac vein + - + + + + fma + FMA:21185 + Femoral vein + + + + + + + + + Tubular organ part, the wall and lumen of which are continuous with those of the ventricles of the heart, directly or indirectly through branches of the aorta and pulmonary trunk. Examples: bronchial artery, hepatic artery, coronary artery, truncus anterior of right pulmonary artery, aorta. + + Trunk of artery + fma + FMA:30313 + Arterial trunk + + + + + + + + + Anatomical cluster which consists of all or some members of one or more organ subclasses which are grouped together according to some shared attributes. Examples: abdominal viscera, pelvic viscera. + + fma + FMA:32406 + Organ cluster + + + Hollow tree, the organ parts of which are arteries, veins or lymphatic vessels. Examples: systemic arterial tree (organ), portal venous tree (organ), thoracic duct tree. + + fma + FMA:3710 + Vascular tree - + + + + Trunk of aortic tree + Trunk of systemic arterial tree + fma + FMA:3734 + Aorta + - + + + + Carotid artery + Trunk of common carotid tree + fma + FMA:3939 + Common carotid artery + + + + + + + + + + Muscularis layer + fma + FMA:45634 + Muscle layer + - + + + Vascular tree, the organ parts of which are arteries. Examples: There are only two canonical instances, systemic arterial tree (organ) and pulmonary arterial tree (organ). + + fma + FMA:45840 + Arterial tree organ + + + + + + + + + Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells, cell parts or body part subdivisions that are adjacent to, or continuous with one another; does not constitute a cell part, cell, tissue, organ, organ system or organ system subdivision, cardinal body part, body part subdivision or anatomical junction. Examples: joint, adnexa of uterus, root of lung, renal pedicle, back. + + fma + FMA:49443 + Anatomical cluster + + + + + + + + + + Ophthalmic arterial branch + fma + FMA:49872 + Branch of ophthalmic artery + - + + + + Central artery of retina + Retinal artery + Zinn's artery + fma + FMA:49879 + Central retinal artery + - + + + Systemic artery which supplies the heart. + + Coronary arterial tree + fma + FMA:49893 + Coronary artery + + + + + + + + + + fma + FMA:49918 + Systemic arterial trunk + - + + + Subdivision of arterial tree (organ) which consists of branching sets of tubes (arterial trunk) that form a tree; together with other arterial trees (organ part), it constitutes an arterial tree (organ). Examples: pulmonary arterial tree, right coronary arterial tree, superior mesenteric tree. + + Arterial subtree + Arterial tree organ part + Arterial vessel + fma + FMA:50720 + Artery + + + + Vascular tree organ region + fma + FMA:50722 + Region of vascular tree organ - + + + Subdivision of venous tree (organ) which consists of branching sets of tubes (venous trunks) that form a tree; together with other venous trees (organ part), it constitutes a venous tree (organ). Examples: subclavian venous tree, jugular tree, extrahepatic portal tree, common iliac venous tree. + + Venous subtree + Venous tree organ part + Venous vessel + fma + FMA:50723 + Vein + - + + + + Cranial dural venous sinus + Dural sinus + fma + FMA:50762 + Dural venous sinus + - + + + + Lateral sinus + fma + FMA:50763 + Transverse sinus + + + + + + + + + + fma + FMA:50772 + Cavernous sinus + - + + + Segment of neuraxis that has as its parts gray matter and white matter that surround the cerebral ventricular system; Examples: There is only one brain. + + fma + FMA:50801 + Brain + + + + + + + + + + fma + FMA:52568 + Paired dural venous sinus + + + + + + + + + Organ component layer which consists of the endothelium and the fibroelastic connective tissue. + + fma + FMA:55589 + Tunica intima + + + + + + + + + Organ the unshared parts of which surround one or more macroscopic anatomical spaces. Examples: neuraxis, tooth, esophagus, heart, long bone, corpus spongiosum of penis. + + fma + FMA:55671 + Cavitated organ + + + + + + + + + Cavitated organ in which its unshared parts surround one continuous anatomical space. Examples: stomach, urinary bladder, esophagus, uterine tube. + + fma + FMA:55672 + Organ with organ cavity + + + + + + + + + Cavitated organ in which its unshared parts surround two or more macroscopic anatomical spaces. Examples: heart, long bone, corpus spongiosum of penis, bulb of vestibule. + + fma + FMA:55673 + Organ with cavitated organ parts + + + + + + + + + Organ with organ cavity, which consists of an arborizing set of tubular organ parts, the walls of which are continuous and surround a continuous lumen. Examples: systemic arterial tree (organ), tracheobronchial tree, biliary tree. + + fma + FMA:55677 + Hollow tree organ + - + + + + fma + FMA:6266 + Subdivision of conducting system of heart + - + + + Subdivision of vascular tree (organ) which connects an arteriole to a venule or vice-versa. + + Blood capillary + Capillary vessel + fma + FMA:63194 + Capillary + - + + + + Pulmonary arterial tree + Pulmonary arterial tree organ part + fma + FMA:66326 + Pulmonary artery + + + + + + + + + + Systemic arterial subtree + fma + FMA:66464 + Systemic artery + + + + + + + + + + Systemic venous tree organ part + fma + FMA:66644 + Systemic vein + - + + + + Portal venous tree organ part + fma + FMA:66645 + Portal vein + + + + + + + + + Material anatomical entity which is generated by coordinated expression of the organism's own genes that guide its morphogenesis; has inherent 3D shape; its parts are connected and spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor. + + Biological structure + fma + FMA:67135 + Anatomical structure + @@ -8882,6 +20313,101 @@ This class was relocated as a son of BFO 'Material entity', and BFO 2.0 'located in at all times' relations were added between relevant FMA classes; they should ultimately be replaced by a genuine version of FMA using BFO 2.0 relations. + Physical anatomical entity which has mass. Examples: hemoglobin molecule, mitochondrion, hepatocyte, erythrocyte, heart, head, blood, urine. + + fma + FMA:67165 + Material anatomical entity + + + + + + + + + Anatomical structure which has as its direct parts portions of two or more types of tissue or two or more types of cardinal organ part which constitute a maximally connected anatomical structure demarcated predominantly by a bona fide anatomical surface. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary. + + fma + FMA:67498 + Organ + + + + + + + + + + fma + FMA:67611 + Anatomical valve + + + + + + + + + Cardinal organ part which is a fiat subdivision of an organ. Examples: lingula of left lung, tail of pancreas, artery, trochanter, nodulus of semilunar valve, right side of heart, duodenum, fundus of stomach. + + fma + FMA:67619 + Organ region + + + + + + + + + Tissue which consists of striated muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue, Cardiac muscle tissue. + + fma + FMA:67905 + Striated muscle tissue + + + + + + + + + + Common carotid arterial subdivision + fma + FMA:70504 + Subdivision of common carotid artery + + + + + + + + + + Branch of internal carotid artery + Internal carotid arterial subdivision + fma + FMA:70506 + Subdivision of internal carotid artery + + + + + + + + + + fma + FMA:70523 + Subdivision of cerebral part of internal carotid artery @@ -8889,105 +20415,360 @@ + + + fma + FMA:7088 + Heart - - - - - - - + + + + + + + + + Organ chamber which consists of a wall that surrounds the cavity of a cardiac atrium or ventricle. + + Chamber of heart + fma + FMA:7095 + Cardiac chamber + + + + + + + + + Right cardiac chamber which is continuous with the superior vena cava and inferior vena cava. + + Right atrium of heart + fma + FMA:7096 + Right atrium + + + + + + + + + Left cardiac chamber which is continuous with the pulmonary venous trunk. + + Left atrium of heart + fma + FMA:7097 + Left atrium + + + + + + + + + Right cardiac chamber which is continuous with the pulmonary arterial trunk. + + Right ventricle of heart + fma + FMA:7098 + Right ventricle + + + + + + + + + Cardiac chamber which consists of a wall that surrounds the cavity of an atrium. + + Atrium of heart + fma + FMA:7099 + Cardiac atrium + + + + + + + + + Cardiac chamber which consists of a wall that surrounds the cavity of a ventricle. + + Lower chamber of heart + Ventricle of heart + fma + FMA:7100 + Cardiac ventricle + + + + + + + + + Left cardiac chamber which is continuous with the aorta. + + Left ventricle of heart + fma + FMA:7101 + Left ventricle + + + + + + + + + + + + + + + Anatomical valve which has as its parts the endocardium and fibroelastic connective tissue attached to the fibrous ring of heart. + + Heart valve + Valve of heart + fma + FMA:7110 + Cardiac valve + + + + + + + + + Anatomical structure, which has as its direct parts instances of one or more organ types which are interconnected with one another by zones of continuity. Examples: skeletal system, cardiovascular system, alimentary system. + + fma + FMA:7149 + Organ system + + + + + + + + + Organ system which consists of the heart, the systemic and pulmonary arterial and venous system, the lymphatic and the portal venous system. + + fma + FMA:7161 + Cardiovascular system + + + + + + + + + Cardiac valve which has as its parts the leaf of cardiac valve that separates the atrium from the ventricle. + + fma + FMA:7233 + Atrioventricular valve - + - + + + Atrioventricular valve which has as its parts the anterior, posterior and septal leaflets, attached to the fibrous ring of tricuspid valve. + + Right atrioventricular valve + fma + FMA:7234 + Tricuspid valve + - + - + + + Atrioventricular valve which has as its parts the anterior and posterior leaflets, attached to the fibrous ring of mitral valve. + + Bicuspid valve + Left atrioventricular valve + fma + FMA:7235 + Mitral valve + - + - + + + Cardiac valve which has as its parts the anterior, right posterior and left posterior cusps, attached to the fibrous ring of aortic valve. + + fma + FMA:7236 + Aortic valve + - + - + + + Cardiac valve which has as its parts the right anterior, left anterior and posterior cusps, attached to the fibrous ring of pulmonary valve. + + Pulmonic valve + fma + FMA:7246 + Pulmonary valve + - + - + + + Tunica intima which has as its parts the endothelium of endocardium and the fibroelastic connective tissue that surrounds the cavity of a cardiac chamber. + + fma + FMA:7280 + Endocardium - + - + + + + Brachiocephalic venous subdivision + Tributary of brachiocephalic vein + fma + FMA:77883 + Subdivision of brachiocephalic vein + - + - + + + + Superior vena caval tree subdivision + fma + FMA:78048 + Subdivision of superior vena caval tree + - + - + + + + Inferior vena caval tree subdivision + fma + FMA:78049 + Subdivision of inferior vena caval tree + - + - + + + + External iliac venous subdivision + fma + FMA:78204 + Subdivision of external iliac vein + - + - + + + anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas. + + fma + FMA:82472 + Cardinal organ part + - + - - - - - - - + + + + fma + FMA:82481 + Organ chamber + + + + + + + + + + fma + FMA:82485 + Organ component layer + + + + + + + + + Organ component which is part of the brain or spinal cord. + + fma + FMA:83153 + Organ component of neuraxis @@ -8995,12 +20776,31 @@ + + + Specialized conducting tissue of heart + Specialized muscle tissue of heart + fma + FMA:83378 + Conducting tissue of heart + + + + + + + + + + fma + FMA:85353 + Muscle layer of organ @@ -9008,12 +20808,49 @@ + + + Myocardial zone + Myocardium region + Zone of myocardium + fma + FMA:86044 + Region of myocardium + + + + + + + + + Cardinal organ part which is a fiat subdivision of an organ component. Examples: cervical part of wall of esophagus, mucosa of body of stomach. + + Organ component region + fma + FMA:86103 + Region of organ component + + + + + + + + + Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball. + + Organ region with fixed fiat boundary + Segment of organ + fma + FMA:86140 + Organ segment @@ -9021,12 +20858,18 @@ + + + Arterial tree organ segment + fma + FMA:86187 + Segment of arterial tree organ @@ -9034,12 +20877,30 @@ + + + Venous tree organ segment + fma + FMA:86188 + Segment of venous tree organ + + + + + + + + + + fma + FMA:86212 + Region of wall of heart @@ -9047,12 +20908,20 @@ + + Muscle layer of organ which has as its parts the myocardium proper and the conducting system of the heart. + + Heart muscle + Muscle of heart + fma + FMA:9462 + Myocardium @@ -9060,12 +20929,19 @@ + + Myocardium of ventricle which is continuous with the tunica media of the pulmonary trunk. + + Right ventricular myocardium + fma + FMA:9535 + Myocardium of right ventricle @@ -9073,12 +20949,73 @@ + + Myocardium of ventricle which is continuous with the tunica media of aorta. + + Left ventricular myocardium + fma + FMA:9558 + Myocardium of left ventricle + + + + + + + + + Anatomical structure which has as its parts cells of predominantly one type with or without intercellular matrix. Examples: epithelium, muscle tissue, connective tissue, neural tissue, lymphoid tissue. + + Tissue + fma + FMA:9637 + Portion of tissue + + + + + + + + + Tissue which consists of muscle cells surrounded by a reticulum of collagen fibers or fine connective tissue [endomysium]. Examples: Smooth muscle, Cardiac muscle. + + Muscle tissue + fma + FMA:9641 + Portion of muscle tissue + + + + + + + + + Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa. + + fma + FMA:9689 + Serous sac + + + + + + + + + Serous sac, which has as parts the serous pericardium and the pericardial cavity . Examples: There is only one pericardial sac. + + fma + FMA:9868 + Pericardial sac @@ -9086,12 +21023,18 @@ + + Organ cluster which has as its parts the fibrous pericardium and the pericardial sac. + + fma + FMA:9869 + Pericardium @@ -9101,6 +21044,12 @@ In order to obtain the taxonomy of diseases / disorders / pathological process in CVDO, it is necessary to use the reasoner first and to look at the inferred class hierarchy. + A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:21:20Z + + disease @@ -9109,13 +21058,27 @@ + A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:39:44Z + + disorder - + + + A disorder whose etiology involves an abnormality in the nucleotide sequence of an organism's genome. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:41:14Z + + genetic disorder + @@ -9123,6 +21086,12 @@ + A process in an organism that leads to a subsequent disorder. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:53:07Z + + etiological process @@ -9131,6 +21100,10 @@ + Albert Goldfain + creation date: 2009-06-23T11:53:49Z + + bodily process @@ -9139,6 +21112,12 @@ + A bodily process that is clinically abnormal. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:54:29Z + + pathological bodily process @@ -9147,25 +21126,55 @@ + The totality of all processes through which a given disease instance is realized. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:55:44Z + + disease course - + + + A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:56:26Z + + chronic disease course + - + + + A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, involve an increasing deviation from homeostasis. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:57:09Z + + progressive disease course + - + + + A disease course that terminates in a return to normal homeostasis. + Albert Goldfain + http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf + creation date: 2009-06-23T11:57:44Z + + transient disease course + @@ -9173,13 +21182,122 @@ + An anatomical structure (FMA) is pathological whenever (1) it has come into being as a result of changes in some pre-existing canonical anatomical structure, (2) through processes other than the expression of the normal complement of genes of an organism of the given type, and (3) is predisposed to have health-related consequences for the organism in question manifested by symptoms and signs. + Albert Goldfain + http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf + creation date: 2009-07-13T02:14:05Z + + pathological anatomical structure - + + + a disease course with a rapid onset but typical unfolding of signs and symptoms after this rapid onset. + Albert Goldfain + http://code.google.com/p/ogms/wiki/Meeting_notes_20100513 + creation date: 2010-07-19T11:57:44Z + + acute disease course + + + + + + + + + + + + + example to be eventually removed + + + + + + + + Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. + metadata complete + + + + + + + + term created to ease viewing/sort terms for development purpose, and will not be included in a release + organizational term + + + + + + + + Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." + ready for release + + + + + + + + Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. + metadata incomplete + + + + + + + + Nothing done yet beyond assigning a unique class ID and proposing a preferred term. + uncurated + + + + + + + + All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the definition editor. + pending final vetting + + + + + + + + Terms with this status should eventually replaced with a term from another ontology. + Alan Ruttenberg + group:OBI + to be replaced with external ontology term + + + + + + + + A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. + Alan Ruttenberg + group:OBI + requires discussion + @@ -9191,66 +21309,25 @@ /////////////////////////////////////////////////////////////////////////////////////// --> - - intracranial aneurysm disease - - - ruptured thoracoabdominal aortic aneurysm disease - - - A chronic pulmonary heart disease caused by a kyphoscoliosis. - - - A restrictive cardiomyopathy which results in fibrous lesions of right and left ventricle. It occurs typically in tropical and subtropical Africa. - - - thoracic aortic aneurysm disease - - - splenic artery aneurysm disease - - - A congestive heart failure caused by a rheumatic fever. - - - An ischemia occurring in the spinal cord. - - - coronary aneurysm disease + + Person:Alan Ruttenberg - - subclavian artery aneurysm disease - - - A thrombosis that occurs in a cavernous sinus. - - - aortic aneurysm disease - - - An aortic valve insufficiency due to rheumatic fever. - - - ruptured aortic aneurysm disease - - - dissecting aortic aneurysm disease - - - ruptured abdominal aortic aneurysm disease - - - abdominal aortic aneurysm disease - - - ruptured thoracic aortic aneurysm disease - - - A myocarditis caused by rheumatic fever. - - - A dilated cardiomyopathy resulting from a pregnancy. It presents typically between the last month of pregnancy and up to six months postpartum. + + To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003]) + To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003]) + + + + To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003]) + + + + + + To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003]) + + PlainLiteral @@ -9268,6 +21345,230 @@ /////////////////////////////////////////////////////////////////////////////////////// --> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -9304,5 +21605,5 @@ - + diff --git a/src/catalog-v001.xml b/src/catalog-v001.xml new file mode 100644 index 0000000..d21b464 --- /dev/null +++ b/src/catalog-v001.xml @@ -0,0 +1,14 @@ + + + + + + + + + + + + + + diff --git a/src/cvdo.owl b/src/cvdo.owl new file mode 100644 index 0000000..1d53768 --- /dev/null +++ b/src/cvdo.owl @@ -0,0 +1,9308 @@ + + + + + + + + + Adrien Barton + Arnaud Rosier + Jean-François Ethier + Paul Fabry + http://creativecommons.org/licenses/by/4.0/ + Cardio Vascular Disease Ontology + CVDO is an ontology of cardiovascular diseases structured on OBO foundry’s principle and based on BFO. CVDO reorganizes and completes DOID cardiovascular diseases following OGMS tripartite model of disease, and builds its taxonomy of diseases largely by automatic reasoning. + 2024-05-17 + + + + + + + + + + + + + This annotation property is created temporarily for better visibility of the distinction between DOID definitions and updated CVDO definition (when a DOID definition of a class did not need to be changed, no additional CVDO definition was included). Ultimately, 'CVDO definition' annotation properties should be replaced by 'definition' annotation properties. + CVDO definition + + + + + + + + + This annotation property is created temporarily for better visibility of the CVDO notes, in particular those that concern DOID classes. Ultimately, 'CVDO editor note' annotation properties should be replaced by 'editor note' annotation properties, or removed. + CVDO editor note + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + CVDO adds the property chain that if A occurs_in B and B located_in_at_all_times C, then A occurs_in C. This is used for a few inferences in the ontology, but CVDO can be used without problem without this property chain. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An endocarditis caused by bacterial infection. + bacterial endocarditis + + + + + + + + + An endocarditis caused by viral infection. + viral endocarditis + + + + + + + + + An endocarditis caused by fungal infection. + fungal endocarditis + + + + + + + + + + + + + + + + + + + A disorder located in the heart. + heart disorder + + + + + + + + + + + + + + + + + + + A disorder always located in a blood vessel. + vascular disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the endocardium. + endocardium disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the pericardium. + Since the pericardium is not a part of the heart according to FMA, pericardium disorder is not classified as a heart disorder. + pericardium disorder + + + + + + + + + A pericarditis caused by an infection. + infectious pericarditis + + + + + + + + + A pericarditis caused by a bacterial infection. + bacterial pericarditis + + + + + + + + + A pericarditis caused by a viral infection. + viral pericarditis + + + + + + + + + A pericarditis caused by a fungal infection. + fungal pericarditis + + + + + + + + + protozoal pericarditis + + + + + + + + + + + + + + + + + + + A pathological process involving or occuring in the heart. + heart pathological process + + + + + + + + + + + + + + + + + + + A pathological process involving or occuring in the pericardium. + pericardium pathological process + + + + + + + + + + + + + + + + + + + A pericarditis that has an acute disease course. + acute pericarditis + + + + + + + + + + + + + + + + + + + A pericarditis that has a chronic disease course. + chronic pericarditis + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + atrioventricular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + first degree atrioventricular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Mobitz I second degree atrioventricular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + complete heart block + third degree atrioventricular block (disease) + + + + + + + + + + + + + + + + + + + A disorder always loacted in the conducting tissue of the heart. + heart conduction disorder + + + + + + + + + impaired atrioventricular node + + + + + + + + + impaired right branch of atrioventricular bundle + + + + + + + + + bundle of Kent + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + sinoatrial block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Wenckebach block + Mobitz I second degree sinoatrial block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + sinus exit block + Mobitz II second degree sinoatrial block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + first degree sinoatrial block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + third degree sinoatrial block (disease) + + + + + + + + + impaired sinoatrial node + + + + + + + + + + + + + + + + + + + + + + + + + + + + + heart block (disease) + + + + + + + + + impaired posterior division of left branch of atrioventricular bundle + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + left posterior fascicular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + infra-hisian block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + left bundle branch block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A heart conduction disease characterized by cardiac arrhythmia processes. + Usual medical language does not differentiate the disease and the corresponding pathological process for the different kinds of cardiac arrhythmias. CVDO distinguishes them explicitly with the suffix '(disease)' or '(process)'. + cardiac arrhythmia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + atrial fibrillation (disease) + + + + + + + + + atrial fibrillation (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + atrial flutter (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + cavotricuspid isthmus dependant macroreentry tachycardia + type I atrial flutter + common atrial flutter (disease) + + + + + + + + + + + + + + + A pathological process of fibrosis of the cardiac atrium. + cardiac atrium fibrosis + + + + + + + + + supraventricular tachycardia (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + bradycardia (disease) + + + + + + + + + bradycardia (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + premature atrial contraction (disease) + + + + + + + + + left anterior fascicle + + + + + + + + + + + + + + + + + + + A disorder always located in a heart valve. + heart valve disorder + + + + + + + + + + + + + + + + + + + + + + + + + wandering pacemaker + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the tricuspid valve of the heart. + tricuspid valve disease + + + + + + + + + + + + + + + A degenerated structure in a mitral valve leaflet due to myxomatous proliferation. + myxomatous degenerated structure in a mitral valve leaflet + + + + + + + + + + + + + + + + + + + + + + + A heart pathological process that has a heart valve as a participant. + This class should not be confused with 'heart valve pathological process', which are pathological processes occurring in a heart valve, rather than pathological process having as participant a heart valve. + heart pathological process involving a heart valve + + + + + + + + + + + + + + + + + + + + + + + mitral valve leaflet displacement into the left atrium during left ventricular systole + + + + + + + + + + + + + + + + + + + + + + + tricuspid valve leaflet displacement into the right atrium during right ventricular systole + + + + + + + + + + + + + + + + + + + + + + + aortic valve leaflet displacement into the left ventricle during left ventricular diastole + + + + + + + + + + + + + + + + + + + heart valve leaflet displacement into a cardiac chamber during ventricular systole + + + + + + + + + + + + + + + + + + + + + + + mitral valve improper close during left ventricular systole + + + + + + + + + retrograd blood flow through mitral valve during left ventricular systole + + + + + + + + + retrograd blood flow through pulmonary valve during right ventricular diastole + + + + + + + + + + + + + + + + + + + + + + + pulmonary valve improper close during right ventricular diastole + + + + + + + + + + + + + + + + + + + + + + + tricuspid valve improper close during right ventricular systole + + + + + + + + + + + + + + + + + + + + + + + aortic valve improper close during left ventricular diastole + + + + + + + + + retrograd blood flow through tricuspid valve during right ventricular systole + + + + + + + + + retrograd blood flow through aortic valve during left ventricular diastole + + + + + + + + + disturbed anterograd blood flow through mitral valve during left ventricular diastole + + + + + + + + + retrograd blood flow through a heart valve + + + + + + + + + disturbed anterograd blood flow through a heart valve + + + + + + + + + disturbed anterograd blood flow through tricuspid valve during right ventricular diastole + + + + + + + + + disturbed anterograd blood flow through pulmonary valve during right ventricular systole + + + + + + + + + disturbed anterograd blood flow through aortic valve during left ventricular systole + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which some disorder of a heart valve prevents it from opening properly, occasioning disturbance in the anterograd blood flow through the valve. + heart valve stenosis + + + + + + + + + impaired cardiac output + + + + + + + + + pressure + + + + + + + + + blood pressure + + + + + + + + + A pathological process of highly pressured aerterial blood flow. + highly pressured arterial blood flow + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which an abnormal structure in a heart valve prevents it to close propertly, occasioning a retrograd blood flow through the valve. + heart valve insufficiency + + + + + + + + + + + + + + + + + + + + + A pathological process of a heart valve closing improperly. + heart valve improper close + + + + + + + + + + + + + + + + + + + A disorder always located in a vein. + vein disorder + + + + + + + + + + + + + + + + + + + + A pathological process involving or occuring in a blood vessel. + vascular pathological process + + + + + + + + + + + + + + + A pathological process of formation of a blood clot inside a blood vessel, obstructing the flow of blood. + thrombosis + + + + + + + + + A thrombosis occurring in a deep vein. + deep vein thrombosis + + + + + + + + + + + + + + + A pathological process of an artery hardening. + artery hardening + + + + + + + + + + + + + + + A pathological process of formation of atheromous plaques in an artery. + atheromous plaque formation in artery + + + + + + + + + + + + + + + + + + + + + A pathological process of lodging of an embolus in a blood vessel. + embolism + + + + + + + + + + + + + + + A disorder of localized, blood-filled balloon-like bulge in the wall of a blood vessel. + aneurysm (disorder) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ischemic disease + + + + + + + + + compression disease + + + + + + + + + + + + + + + An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does not terminate by cardioversion. + permanent atrial fibrillation + + + + + + + + + + + + + + + + + + + A pathological process of dilatation of the myocardium of a right cardiac ventricle. + right ventricular myocardium dilatation + + + + + + + + + + + + + + + + + + + + + A pathological process of an aneurysm rupturing. + aneurysm rupture + + + + + + + + + + + + + + + + + + + A disorder always located in the mycoardium. + myocardium disorder + + + + + + + + + + + + + + + A cardiomyopathy whose etiological process includes a stressful or emotional situation, characterized by transient ventricular apical wall motion abnormalities (ballooning). + Tako-Tsubo cardiomyopathy is not a dilated cardiomyopathy in Elliott et al.'s (2008) classification. + Tako Tsubo cardiomyopathy + + + + + + + + + "A cardiomyopathy characterized by prominent left ventricular trabeculae and deep inter-trabecular recesses. The myocardial wall is often thickened with a thin, compacted epicardial layer and a thickened endocardial layer." (Elliott et al., 2008) + noncompaction cardiomyopathy + left ventricular noncompaction + + + + + + + + + + + + + + + + + + + A hypertrophic cardiomyopathy that has a genetic origin. + genetic hypertrophic cardiomyopathy + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the pericardium. + Since pericardium is not a part of heart according to FMA, pericardium disease is not classified as a heart disease. + pericardium disease + + + + + + + + + This is a dummy class not intended to be included in CVDO's final version, used to store temporarily DOID's vascular diseases that may be reclassified in the future. + vascular disease - unclassified by CVDO + + + + + + + + + + + + + + + + + + + A pathological process occuring in a cardiac atrium. + cardiac atrium pathological process + + + + + + + + + + + + + + + + + + + A pathological process occurring in a cardiac ventricle. + cardiac ventricle pathological process + + + + + + + + + + + + + + + + + + + + + + + + + + + A pathological process constituted by a thrombosis (creating a blood clot) and a subsequent embolism (involving the blood clot as the embolus). + thromboembolism + + + + + + + + + A necrosis of a tissue caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply. + infarction + + + + + + + + + + + + + + + + + + + + + + + pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole + + + + + + + + + + + + + + + A pathological process involving the blood circuation in the heart. + cardiac blood circulation pathological process + + + + + + + + + + + + + + + A pathological process involving the blood circulation in a blood vessel. + vascular blood circulation pathological process + + + + + + + + + + + + + + + part of atrial myocardium with impaired conduction + + + + + + + + + diabetic microangiopathy + + + + + + + + + diabetic macroangiopathy + + + + + + + + + + + + + + + + + + + A pathological process consisting in the formation of atheromous plaques in a coronary artery. It may lead to a coronary stenosis. + atheromous plaque formation in coronary artery + + + + + + + + + + + + + + + + + + + A coronary heart disease due to a coronary stenosis. + atherosclerotic coronary heart disease + + + + + + + + + + + + + + + + + + + A pathological process of dilatation of the myocardium of a left cardiac ventricle. + left ventricular myocardium dilatation + + + + + + + + + + + + + + + + + + + + + + + + + + + + + supraventricular tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + left atrial flutter (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + right atrial flutter (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + junctional tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + atrioventricular nodal reentrant tachycardia (disease) + + + + + + + + + atrial flutter (process) + + + + + + + + + ventricular fibrillation (process) + + + + + + + + + junctional tachycardia (process) + + + + + + + + + premature atrial contraction (process) + + + + + + + + + A pathological process involving the electrical activity of the heart. + cardiac arrhythmia (process) + + + + + + + + + heart block (process) + + + + + + + + + atrioventricular block (process) + + + + + + + + + infra-hisian block (process) + + + + + + + + + sinoatrial block (process) + + + + + + + + + Mobitz I second degree atrioventricular block (process) + + + + + + + + + Mobitz II second degree atrioventricular block (process) + + + + + + + + + first degree atrioventricular block (process) + + + + + + + + + third degree atrioventricular block (process) + + + + + + + + + left anterior fascicular block (process) + + + + + + + + + left bundle branch block (process) + + + + + + + + + left posterior fascicular block (process) + + + + + + + + + right bundle branch block (process) + + + + + + + + + Mobitz I second degree sinoatrial block (process) + + + + + + + + + Mobitz II second degree sinoatrial block (process) + + + + + + + + + first degree sinoatrial block (process) + + + + + + + + + third degree sinoatrial block (process) + + + + + + + + + + + + + + + + + + + A disorder always located in a coronary artery. + coronary artery disorder + + + + + + + + + + + + + + + A pathological process of dilatation of the myocardium of a cardiac ventricle. + ventricular myocardium dilatation + + + + + + + + + + + + + + + A pathological process of hypertrophy of the myocardium of a cardiac ventricle. + ventricular myocardium hypertrophy + + + + + + + + + + + + + + + + + + + A pathological process of hypertrophy of the myocardium of a left cardiac ventricle. + left ventricular myocardium hypertrophy + + + + + + + + + + + + + + + + + + + A pathological process of hypertrophy of the myocardium of a right cardiac ventricle. + right ventricular myocardium hypertrophy + + + + + + + + + A pathological process of an organ or part of organ getting inflamed. + pathological inflammation process + + + + + + + + + + + + + + + + + + + An inflammation process occurring in the myocardium. + inflammation process in a myocardium + + + + + + + + + + + + + + + + + + + An inflammation process occurring in the endocardium. + inflammation process in an endocardium + + + + + + + + + + + + + + + + + + + An inflammation process occurring in the pericardium. + inflammation process in a pericardium + + + + + + + + + + + + + + + + + + + An inflammation process occurring in the aorta. + inflammation process in aorta + + + + + + + + + + + + + + + + + + + An inflammation process in a blood vessel. + inflammation process in a blood vessel + + + + + + + + + + + + + + + + + + + An inflammation process occurring in the femoral vein. + inflammation process in a femoral vein + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An inflammation process occurring in an iliac vein. + inflammation process in an iliac vein + + + + + + + + + + + + + + + + + + + An inflammation of the retinal artery. + inflammation process in a retinal artery + + + + + + + + + + + + + + + + + + + An inflammation process occurring in a vein. + inflammation process in a vein + + + + + + + + + + + + + + + + + + + + + A pathological process of fibrofatty replacement in the myocardium of the right cardiac ventricle. + fibrofatty replacement in a right ventricular myocardium + + + + + + + + + + + + + + + A disorder of degenerated structure in a heart valve leaflet. + degenerated structure in a heart valve leaflet + + + + + + + + + + + + + + + + + + + A disorder of degenerated structure in an aortic valve leaflet. + degenerated structure in an aortic valve leaflet + + + + + + + + + + + + + + + + + + + A disorder of degenerated structure in a mitral valve leaflet. + degenerated structure in a mitral valve leaflet + + + + + + + + + + + + + + + + + + + A (clinically abnormal) degenerated structure in a tricuspid valve leaflet. + degenerated structure in a tricuspid valve leaflet + + + + + + + + + + + + + + + + + + + A disorder of degenerated structure in a pulmonary valve leaflet. + degenerated structure in a pulmonary valve leaflet + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A mitral valve prolapse due to myxomatous proliferation in the mitral valve. + Barlow's syndrome + + + + + + + + + + + + + + + A pathological process consisting in the abnormal accumulation of fluid in the pericardial cavity. + A process of pericardial effusion leads to the disorder 'fluid in the pericardial cavity'. + fluid accumulation in the pericardial cavity + + + + + + + + + + + + + + + An ischemic cardiomyopathy due to coronary stenosis. + atherosclerotic ischemic cardiomyopathy + + + + + + + + + An atrial fibrillation disease that is characterized by an atrial fibrillation episode shorter than 7 days. + paroxysmal atrial fibrillation + + + + + + + + + An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does terminate by cardioversion. + persistent atrial fibrillation + + + + + + + + + premature contraction (process) + + + + + + + + + premature junctional contraction (process) + + + + + + + + + premature ventricular contraction (process) + + + + + + + + + sinus pause + sinoatrial arrest (process) + + + + + + + + + sinus bradycardia (process) + + + + + + + + + tachyarrhythmia (process) + tachycardia (process) + + + + + + + + + left atrial flutter (process) + + + + + + + + + right atrial flutter (process) + + + + + + + + + common atrial flutter (process) + + + + + + + + + atrioventricular nodal reentrant tachycardia (process) + + + + + + + + + ventricular tachycardia (process) + + + + + + + + + monomorphic ventricular tachycardia (process) + + + + + + + + + torsades de pointes (process) + + + + + + + + + ventricular flutter (process) + + + + + + + + + inappropriate sinus tachycardia (process) + + + + + + + + + ventricular preexcitation (process) + + + + + + + + + + + + + + + + + + + A pathological process of a coronary artery hardening. + coronary artery hardening + + + + + + + + + accessory bundle + + + + + + + + + Accessory bundle that connects the atrium to a ventricle outside of the regular atrioventricular conduction system. + atrioventricular accessory bundle + + + + + + + + + impaired sinus node + + + + + + + + + + + + + + + + + + + + + + + + + A sick sinus syndrome characterized by sinus pauses and/or bradycardia episodes alternating with sinus or atrial tachycardia episodes. + tachycardia-bradycardia syndrome + + + + + + + + + + + + + + + + + + + + + + + + + + + + + inappropriate sinus tachycardia (disease) + + + + + + + + + + + + + + + + + + + A disease cause by a cardiac ion channel disorder. + cardiac channelopathy + + + + + + + + + A cardiac channelopathy in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. This is a rare disease. + long QT syndrome + + + + + + + + + + + + + + + + + + + A cardiac channelopathy that has a genetic origin. + genetic cardiac channelopathy + + + + + + + + + + + + + + + + + + + + + + + + + + + + + sinus bradycardia (disease) + + + + + + + + + left bundle branch block (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + tachyarrhythmia (disease) + tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + sinoatrial arrest (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + atrioventricular reciprocating tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ventricular tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ventricular flutter (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + torsades de pointes (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + monomorphic ventricular tachycardia (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ventricular fibrillation (disease) + + + + + + + + + ventricular tachyarrhythmia (process) + + + + + + + + + atrioventricular reciprocating tachycardia (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + premature contraction (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + premature junctional contraction (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + premature ventricular contraction (disease) + + + + + + + + + + + + + + + + + + + A pathological process occurring in a cardiac chamber. + cardiac chamber pathological process + + + + + + + + + + + + + + + + + + + A disorder always located in the mitral valve. + mitral valve disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the aortic valve. + aortic valve disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the tricuspid valve. + tricuspid valve disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the pulmonary valve. + pulmonary valve disorder + + + + + + + + + + + + + + + + + + + + + A pathological process of a heart valve improper opening. + heart valve improper opening + + + + + + + + + + + + + + + + + + + + + + + aortic valve improper opening during left ventricular systole + + + + + + + + + + + + + + + + + + + + + + + mitral valve narrowed opening during left ventricular diastole + + + + + + + + + + + + + + + + + + + + + + + pulmonary valve narrowed opening during right ventricular systole + + + + + + + + + + + + + + + + + + + + + + + tricuspid valve narrowed opening during right ventricular diastole + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A coronary heart disease leading to stable angina. + coronary heart disease with stable angina + + + + + + + + + + + + + + + + + + + An acute coronary syndrome due to coronary stenosis. + atherosclerotic acute coronary syndrome + + + + + + + + + + + + + A heart ischemia accompanied by pain. + Angina pectoris is sometimes taken to refer to the pain itself, rather than to the pathological process behind it. + angina pectoris + + + + + + + + + An angina that is not unstable. + stable angina pectoris + + + + + + + + + + + + + + + + + + + + + + + + + An angina that worsens. It has at least one of these three features: +1. it occurs at rest (or with minimal exertion), usually lasting >10 min +2. it is severe and of new onset (i.e., within the prior 4–6 weeks) +3. it occurs with a crescendo pattern (i.e., distinctly more severe, prolonged, or frequent than before). + unstable angina pectoris + + + + + + + + + + + + + + + + + + + + + + + A heart pathological process that has a mitral valve as a participant. + heart pathological process involving a mitral valve + + + + + + + + + + + + + + + + + + + + + + + A heart pathological process that has an aortic valve as a participant. + heart pathological process involving an aortic valve + + + + + + + + + + + + + + + + + + + + + + + A heart pathological process that has a tricuspid valve as a participant. + heart pathological process involving a tricuspid valve + + + + + + + + + + + + + + + + + + + + + + + A heart pathological process that has a pulmonary valve as a participant. + heart pathological process involving a pulmonary valve + + + + + + + + + + + + + + + + + + + heart valve leaflet displacement into a cardiac chamber during ventricular diastole + + + + + + + + + + + + + + + ventricular systole + + + + + + + + + + + + + + + ventricular diastole + + + + + + + + + atrial systole + + + + + + + + + atrial diastole + + + + + + + + + + + + + + + left ventricular diastole + + + + + + + + + + + + + + + right ventricular diastole + + + + + + + + + + + + + + + left ventricular systole + + + + + + + + + + + + + + + right ventricular systole + + + + + + + + + left atrial systole + + + + + + + + + right atrial systole + + + + + + + + + left atrial diastole + + + + + + + + + right atrial diastole + + + + + + + + + + + + + + + + + + + + + A pathological process of a heart valve being displaced into a cardiac chamber. + heart valve leaflet displacement into a cardiac chamber + + + + + + + + + + + + + + + A disorder of fluid in the pericardial cavity. + fluid in the pericardial cavity + + + + + + + + + A disorder of blood in the pericardial cavity. + blood in the pericardial cavity + + + + + + + + + + + + + + + heart conduction pathological process + + + + + + + + + anomalous atrioventricular excitation (process) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ventricular preexcitation (disease) + + + + + + + + + A disorder in the heart conduction system that causes a disturbed function of ion channel subunits or the proteins that regulate them. + cardiac ion channels disorder + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the displacement of a degenerated pulmonary valve leaflet into the right ventricle during diastole. + pulmonary valve prolapse + + + + + + + + + impaired anterior division of left branch of atrioventricular bundle + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ventricular tachyarrhythmia (disease) + + + + + + + + + + + + + + + + + + + An inflammation process occurring in a heart valve. + inflammation process in a heart valve + + + + + + + + + heart bodily process + + + + + + + + + + + + + + + + + + + A dilated cardiomyopathy that has a genetic origin. + genetic dilated cardiomyopathy + + + + + + + + + + + + + + + + + + + A cardiomyopathy (2008) that has a genetic origin. + genetic cardiomyopathy + + + + + + + + + + + + + + + A disorder made of a detached, traveling intravascular matter (solid, liquid, or gaseous) carried by circulation. It is capable of creating an arterial occlusion at a site distant from its point of origin. + embolus + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation process. + inflammatory disease + + + + + + + + + + + + + + + + + + + A pathological process occurring in the myocardium. + myocardium pathological process + + + + + + + + + + + + + + + + + + + + A pathological process involving or occuring in the aorta. + aorta pathological process + + + + + + + + + + + + + + + + + + + A disorder always located in the aorta. + aorta disorder + + + + + + + + + + + + + + + + + + + + A pathological process occuring in the endocardium. + endocardium pathological process + + + + + + + + + + + + + + + A pathological process of thickening of the endocardium. + endocardium thickening + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the endocardium. + endocardium disease + + + + + + + + + + + + + + + + + + + A disorder always located in the left heart ventricle. + left ventricle disorder + + + + + + + + + + + + + + + + + + + A disorder always located in the right heart ventricle. + right ventricle disorder + + + + + + + + + + + + + + + + + + + A disorder always located in a heart ventricle. + heart ventricle disorder + + + + + + + + + An ischemia of the heart. + heart ischemia + + + + + + + + + + + + + + + + + + + vein pathological process + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An ischemic heart disease leading to a dilatation and dysfunction of the left ventricle. + ischemic cardiomyopathy + + + + + + + + + + + + + + + + + + + A disorder located in an anatomical entity. + material anatomical entity disorder + + + + + + + + + + + + + + + + + + + material anatomical entity pathological process + + + + + + + + + + + + + + + + + + + + cardiovascular system disorder + + + + + + + + + + + + + + + + + + + + cardiovascular system pathological process + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease that affects a material anatomical entity. + disease of material anatomical entity + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An aortic valve stenosis leading to a hypertrophy or dilatation of the left ventricle and its dysfunction. + valvular cardiomyopathy + + + + + + + + + A heart disease in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality. +(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276) + Contemporary (e.g. Elliott et al. 2008) definitions of cardiomyopathy exclude ischemic cardiomyopathy, hypertensive cardiomyopathy and valvular cardiomyopathy. + cardiomyopathy (2008 definition) + + + + + + + + + + + + + + + + + + + left ventricular myocardium contraction dysfunctional process + + + + + + + + + + + + + + + myocardium contraction dysfunctional process + + + + + + + + + + + + + + + + + + + A pathological process occurring in the left heart ventricle. + left ventricle pathological process + + + + + + + + + + + + + + + + + + + A pathological process occurring in the right heart ventricle. + right ventricle pathological process + + + + + + + + + "Inflammatory DCM is defined by the presence of chronic inflammatory cells in association with left ventricular dilatation and reduced ejection fraction". +(Elliott et al., 2008) + inflammatory dilated cardiomyopathy + inflammatory dilated cardiomyopathy + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A hypertensive heart disease leading to a hypertrophy and dysfunction of the left ventricle. + hypertensive cardiomyopathy + + + + + + + + + A heart disease existing at birth, or developping during the first month after birth. + congenital heart disease + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting a heart ventricle. + heart ventricle disease + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting a heart left ventricle. + left ventricle disease + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting a heart right ventricle. + right ventricle disease + + + + + + + + + + + + + + + + + + + ventricular myocardium contraction dysfunctional process + + + + + + + + + + + + + + + + + + + + right ventricular myocardium contraction dysfunctional process + + + + + + + + + + + + + + + myocardium of left ventricle stiffening + + + + + + + + + + + + + + + + + + + A pathological process occurring in a heart valve. + heart valve pathological process + + + + + + + + + + + + + + + + + + + + A pathological process occurring in an aortic valve. + aortic valve pathological process + + + + + + + + + + + + + + + + + + + A pathological process occurring in a mitral valve. + mitral valve pathological process + + + + + + + + + + + + + + + + + + + A pathological process occurring in a tricuspid valve. + tricuspid valve pathological process + + + + + + + + + + + + + + + + + + + A pathological process occurring in a pulmonary valve. + pulmonary valve pathological process + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the myocardium. + myocardium disease + + + + + + + + + + + + + + + + + + + A heart disease that has a genetic disorder. + genetic heart disease + + + + + + + + + A disease existing at birth, or developping during the first month after birth. + congenital disease + + + + + + + + + + + + + + + + + + + coronary artery pathological process + + + + + + + + + + + + + + + A pathological process of coronary artery smooth muscle constriction. + coronary artery smooth muscle constriction + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cardiomyopathy characterized by adipose and fibrosis infiltration in the right ventricular myocardium. It is caused by genetic defects of desmosomes (which are parts of the myocardium) and may result in arrhythmia. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death by ventricular tachyarrhytmia. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An atrial fibrillation disease that has a genetic origin. + familial atrial fibrillation + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Disease of the myocardium associated with cardiac dysfunction. +(Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies) + DOID label "cardiomyopathy" was changed. + + + + + + + + + + + + + + + + + + + + + + + + An endocarditis caused by infection. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + DOID label 'marantic endocarditis' was changed in CVDO (non-bacterial thrombotic endocarditis is a more common name). + marantic endocarditis + non-bacterial thrombotic endocarditis + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + DOID label changed to 'left anterior fascicular block (disease)' for symmetry reasons with 'left posterior fascicular block (disease)' + left anterior fascicular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the conducting tissue of the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of the endocardium. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + DOID label 'anomalous atrioventricular excitation' was changed. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + DOID label changed for homogeneization reasons. + Mobitz II second degree atrioventricular block (disease) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease caused by the presence of fluid in the pericardial cavity (due to pericardial effusion), affecting negatively the heart's pumping function. + In CVDO, cardiac tamponade is defined as *being caused* by a pericardial effusion, rather than as *being* a pericardial effusion. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of a retinal artery. + + + + + + + + + + + + + + + + + + + A thrombosis that occurs in a portal vein. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A coronary heart disease with coronary artery smooth muscle constriction. + + + + + + + + + + + + + + + + + + + A thrombosis occuring in a coronary artery. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + "A heart disease with increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to cause the observed abnormality." +(Elliott et al., 2008, European Heart Journal, 29, 270-276) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cor pulmonale that has a chronic disease course during which the right ventricle becomes hypertrophied. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the cardiovascular system. + + + + + + + + + + + + + + + + + + + + + + + + + A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment. +(adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276) + + + + + + + + + A dilated cardiomyopathy resulting from alcohol intoxication. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A heart conduction disease characterized by inappropriate sinus rates (e.g. sinus bradycardia or sinus pause). + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which an abnormal structure in a pulmonary valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve. + + + + + + + + + + + + + + + + + An embolism due to an embolus made of cholesterol. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which some disorder of the aortic valve leads prevents it from opening properly during left ventricular systole, occasioning disturbance in the anterograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting a blood vessel. + Reorganization of the vascular diseases, and writing of Aristotelian definitions, is still ongoing. + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of the pericardium. + + + + + + + + + + + + + + + + + + + A chronic pericarditis due to rheumatic fever. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A congenital disease involving the narrowing (stenosis) of aorta, hindering the opening of the aortic valve. + Supravalvular aortic stenosis is not classified as an aortic valve stenosis: although the narrowing of the section of the aorta at the exit of the aortic valve implies some improper opening of the aortic valve, the aortic valve is (in general) healthy (there is no disorder nor pathological process inside it). However, this improper opening of the aortic valve is a pathological process that happens inside the heart; therefore, supravalvular aortic stenosis is classified as a heart disease. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A brain ischemia that is part of a transient disease course. + + + + + + + + An ischemia of the brain. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disposition that an aneurysm disorder will lead to pathological processes. + DOID label 'aneurysm disease' changed for homogeneization purpose in CVDO. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A pathological process of restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An ischemic heart disease with narrowing of the coronary arteries. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by reduced blood supply to the heart, occasioning pathological processes in the heart. + + + + + + + + + + + + + + + + + + + + + + A thrombosis occurring in a carotid artery. + + + + + + + + + + + + + + + + + + + An infarction occurring in the brain. + + + + + + + + + + + + + + + A pathological process of disturbance in the blood supply to the brain, causing a loss of brain function. + + + + + + + + + + + + + + A thrombosis that occurs in a dural venous sinus. + + + + + + + + + + + + + + + A thrombosis that occurs in a transverse sinus. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A myocarditis with an acute disease course. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cardiomyopathy (2008) characterized by increased stiffness of the left ventricular myocardium and decreased compliance of the left ventricle (which is restricted from stretching and filling with blood properly), in the absence of dilated cardiomyopathy and hypertrophic cardiomyopathy. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which some disorder of a tricuspid valve prevents it from opening properly during right ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting a valve of the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve. + + + + + + + + + + + + + + + A thrombosis occurring in the brain. + + + + + + + + + + + + + + + A disorder of atheromous plaques in a coronary artery. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A bacterial endocarditis characterized by a slow process of infection. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of the aorta. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the aorta. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the displacement of a degenerated aortic valve leaflet into the left ventricle during diastole. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the displacement of a degenerated tricuspid valve leaflet into the right atrium during systole. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the pulmonary valve of the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + This refers to a narrowing of the section of the left ventricle below the aortic valve; therefore, this was not classified as an aortic valve stenosis in CVDO. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An infarction occurring in the myocardium. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the inability of the heart to pump a sufficient amount of blood throughout the body. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the mitral valve of the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease affecting the aortic valve of the heart. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease in which some disorder of a pulmonary valve prevents it from opening properly during right ventricular systole, occasioning disturbance in the anterograd blood flow through the valve. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of the myocardium. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cor pulmonale that has an acute disease course during which the right ventricle becomes dilated. + 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by a dilatation or hypertrophy of the myocardium of right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs, involving a failure of the right side of the heart. + Although the 1995 classification of cardiomyopathies did not include cor pulmonale, it should have included it, given the definition of cardiomyopathy it adopted. + + + + + + + + + + + + + + + + + + + + + A pathological process consisting in a pulmonary embolism and an infarction that follows. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of a vein. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by an inflammation of a blood vessel. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A coronary heart disease with an acute disease course. + DOID label 'intermediate coronary syndrome' was changed. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + DOID label 'pulmonary subvalvular stenosis' was changed for homogeneization with 'subvalvular aortic stenosis'. + pulmonary subvalvular stenosis + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An embolism that occurs in a pulmonary artery. + + + + + + + + + + + + + + + + A congestive heart failure with impaired ejection fraction. + + + + + + + + + + + + + + + + + + + + + + A congestive heart failure with preserved ejection fraction. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the displacement of a degenerated mitral valve leaflet into the left atrium during systole. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A disease characterized by the displacement of a degenerated heart valve leaflet during systole. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + This class was relocated as a son of BFO 'Material entity', and BFO 2.0 'located in at all times' relations were added between relevant FMA classes; they should ultimately be replaced by a genuine version of FMA using BFO 2.0 relations. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + In order to obtain the taxonomy of diseases / disorders / pathological process in CVDO, it is necessary to use the reasoner first and to look at the inferred class hierarchy. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + intracranial aneurysm disease + + + ruptured thoracoabdominal aortic aneurysm disease + + + A chronic pulmonary heart disease caused by a kyphoscoliosis. + + + A restrictive cardiomyopathy which results in fibrous lesions of right and left ventricle. It occurs typically in tropical and subtropical Africa. + + + thoracic aortic aneurysm disease + + + splenic artery aneurysm disease + + + A congestive heart failure caused by a rheumatic fever. + + + An ischemia occurring in the spinal cord. + + + coronary aneurysm disease + + + subclavian artery aneurysm disease + + + A thrombosis that occurs in a cavernous sinus. + + + aortic aneurysm disease + + + An aortic valve insufficiency due to rheumatic fever. + + + ruptured aortic aneurysm disease + + + dissecting aortic aneurysm disease + + + ruptured abdominal aortic aneurysm disease + + + abdominal aortic aneurysm disease + + + ruptured thoracic aortic aneurysm disease + + + A myocarditis caused by rheumatic fever. + + + A dilated cardiomyopathy resulting from a pregnancy. It presents typically between the last month of pregnancy and up to six months postpartum. + + + PlainLiteral + + + label + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +