diff --git a/DESCRIPTION b/DESCRIPTION index 581981f..48cd488 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -1,7 +1,7 @@ Package: pilot2wrappers Type: Package Title: R Consortium R Submission Pilot 2 -Version: 0.3.0 +Version: 0.4.0 Authors@R: c( person("Eric", "Nantz", email = "theRcast@gmail.com", role = c("aut", "cre")), person("Yilong", "Zhang", role = c("aut")), diff --git a/NEWS.md b/NEWS.md index 4c952ca..0900310 100644 --- a/NEWS.md +++ b/NEWS.md @@ -1,3 +1,9 @@ +# pilot2wrappers 0.4.0 + +- Ensure column width of efficacy table's 95% CI header is wide enough to fit in a single row +- Add missing footnotes to primary table +- Add new vignettes for ADRG as a [Quarto](https://quarto.org/) document (with HTML and PDF output) and cover letter as a R-Markdown document using the [`{pagedown}`](https://pagedown.rbind.io/#letter) package. + # pilot2wrappers 0.3.0 - Enable support for using `{pkglite}` to create package bundle compliant with ECTD submission transfer standards diff --git a/R/tm_t_efficacy.R b/R/tm_t_efficacy.R index 39d2bd1..a96e6a5 100644 --- a/R/tm_t_efficacy.R +++ b/R/tm_t_efficacy.R @@ -49,7 +49,7 @@ ui_t_efficacy <- function(id, datasets) { tags$br(), tags$hr(), fluidRow( - h6(tags$i("*Abbreviation: CI=Confidence Interval; LS=Least Squarses; SD=Standard Deviation")) + h6(tags$i("Abbreviations: CI=Confidence Interval; LS=Least Squarses; SD=Standard Deviation")) ) ) } @@ -136,10 +136,12 @@ srv_t_efficacy <- function(input, output, session, datasets) { "N","Mean (SD)", "N","Mean (SD)","LS Mean (95% CI)") colgr=c(1,2,2,3,3,4,4,4) + colwidths <- c(rep(100, 7), 150) colgrn=c("","Baseline","Week 20","Change from Baseline") - collist = lapply(1:ncol(apr0ancova1),function(xx) colDef(name=coln[xx])) + collist = purrr::map2(1:ncol(apr0ancova1), colwidths, ~{ + colDef(name = coln[.x], minWidth = .y) + }) names(collist) = names(apr0ancova1) - reactable( apr0ancova1, columns = collist, diff --git a/R/tm_t_primary.R b/R/tm_t_primary.R index d21dcfe..c67fdae 100644 --- a/R/tm_t_primary.R +++ b/R/tm_t_primary.R @@ -9,7 +9,12 @@ #' @importFrom shiny NS tagList uiOutput ui_t_primary <- function(id, datasets) { ns <- NS(id) - uiOutput(ns("table")) + tagList( + uiOutput(ns("table")), + p("[1] Based on Analysis of covariance (ANCOVA) model with treatment and site group as factors and baseline value as a covariate."), + p("[2] Test for a non-zero coefficient for treatment (dose) as a continuous variable."), + p("[3] Pairwise comparison with treatment as a categorical variable: p-values without adjustment for multiple comparisons.") + ) } #' srv_t_primary Server Functions diff --git a/inst/golem-config.yml b/inst/golem-config.yml index d74dc30..a29a897 100644 --- a/inst/golem-config.yml +++ b/inst/golem-config.yml @@ -1,6 +1,6 @@ default: golem_name: pilot2wrappers - golem_version: 0.0.0.9000 + golem_version: 0.4.0 app_prod: no adam_path: "datasets/adam" production: diff --git a/vignettes/R Consortium R Submission Pilot 2 Cover Letter.pdf b/vignettes/R Consortium R Submission Pilot 2 Cover Letter.pdf index b77b3f2..ffae457 100644 Binary files a/vignettes/R Consortium R Submission Pilot 2 Cover Letter.pdf and b/vignettes/R Consortium R Submission Pilot 2 Cover Letter.pdf differ diff --git a/vignettes/adrg-quarto.pdf b/vignettes/adrg-quarto.pdf index 41fdfbe..cc7fbba 100644 Binary files a/vignettes/adrg-quarto.pdf and b/vignettes/adrg-quarto.pdf differ diff --git a/vignettes/adrg-quarto.qmd b/vignettes/adrg-quarto.qmd index 590914d..ce82bb6 100644 --- a/vignettes/adrg-quarto.qmd +++ b/vignettes/adrg-quarto.qmd @@ -2,7 +2,7 @@ title: "Analysis Data Reviewer's Guide" author: "R Consortium" subtitle: "R Consortium R Submission Pilot 2" -date: "2022-09-23" +date: "2022-09-26" format: pdf: number-sections: true @@ -14,6 +14,7 @@ format: html: toc: true toc-location: body + self-contained: true execute: echo: false warning: false @@ -33,7 +34,7 @@ library(magrittr) ## Purpose -The Analysis Data Reviewer's Guide (ADRG) provides specific instructions for executing a Shiny application created with the R-language for viewing analysis results and performing custom subpopulation analysis based on the data sets and analytical methods used in the R Consortium R Submission Pilot 1. This document provides context for the analysis datasets and terminology that benefit from additional explanation beyond the Data Definition document (define.xml), as well as a summary of ADaM conformance findings. Appendices 1 and 2 provide detailed procedures for installing and configuring a local R environment to access the previous Pilot 1 content and to install the Shiny application for use within a local R session. +The Analysis Data Reviewer's Guide (ADRG) provides specific instructions for executing a Shiny application created with the R-language for viewing analysis results and performing custom subpopulation analysis based on the data sets and analytical methods used in the R Consortium R Submission Pilot 1. This document provides context for the analysis datasets and terminology that benefit from additional explanation beyond the Data Definition document (define.xml), as well as a summary of ADaM conformance findings. Appendix 1 provides detailed procedures for installing and configuring a local R environment to view the included Shiny application. ## Study Data Standards and Dictionary Inventory @@ -614,7 +615,7 @@ Create a temporary working directory, For example, `C:\tempwork`. Copy all submi The R packages are based on CRAN at 2021-08-31. To install the exact R package versions used in this project, run the code below to set the snapshot repository. -``` r +```r options(repos = "https://mran.microsoft.com/snapshot/2021-08-31") ``` @@ -622,7 +623,7 @@ options(repos = "https://mran.microsoft.com/snapshot/2021-08-31") In the same R session, install the required packages by running the code below. -``` r +```r install.packages(c("haven", "dplyr", "emmeans", "pkglite" , "r2rtf", "rtables", "ggplot2", "cowplot", "visR", "Tplyr", "pharmaRTF", "huxtable")) @@ -632,7 +633,7 @@ install.packages(c("haven", "dplyr", "emmeans", "pkglite" , "r2rtf", The proprietary R package `pilot1wrappers` is packed in the file `r0pkg.txt`. In the same R session, restore the package structures and install them by running the code below. Adjust the output path as needed to use a writable local directory. -``` r +```r pkglite::unpack("r0pkg.txt", output = ".", install = TRUE) ``` @@ -648,7 +649,7 @@ OUTPUT path: To save the analysis results, define the path variable All of these paths must be defined before executing the analysis output program. For example: -``` r +```r path = list( # Modify path to the actual location adam = "path/to/esub/analysis/adam/datasets", @@ -683,7 +684,7 @@ Download and install R 4.1.2 for Windows from code{color:inherit}kbd{padding:.4rem .4rem;font-size:0.875em;color:#fff;background-color:#212529;border-radius:.2rem}kbd kbd{padding:0;font-size:1em;font-weight:700}figure{margin:0 0 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t={placement:this._getPlacement(),modifiers:[{name:"preventOverflow",options:{boundary:this._config.boundary}},{name:"offset",options:{offset:this._getOffset()}}]};return"static"===this._config.display&&(t.modifiers=[{name:"applyStyles",enabled:!1}]),{...t,..."function"==typeof this._config.popperConfig?this._config.popperConfig(t):this._config.popperConfig}}_selectMenuItem({key:t,target:e}){const i=V.find(".dropdown-menu .dropdown-item:not(.disabled):not(:disabled)",this._menu).filter(l);i.length&&v(i,e,t===Ye,!i.includes(e)).focus()}static jQueryInterface(t){return this.each((function(){const e=hi.getOrCreateInstance(this,t);if("string"==typeof t){if(void 0===e[t])throw new TypeError(`No method named "${t}"`);e[t]()}}))}static clearMenus(t){if(t&&(2===t.button||"keyup"===t.type&&"Tab"!==t.key))return;const e=V.find(ti);for(let i=0,n=e.length;ie+t)),this._setElementAttributes(di,"paddingRight",(e=>e+t)),this._setElementAttributes(ui,"marginRight",(e=>e-t))}_disableOverFlow(){this._saveInitialAttribute(this._element,"overflow"),this._element.style.overflow="hidden"}_setElementAttributes(t,e,i){const n=this.getWidth();this._applyManipulationCallback(t,(t=>{if(t!==this._element&&window.innerWidth>t.clientWidth+n)return;this._saveInitialAttribute(t,e);const s=window.getComputedStyle(t)[e];t.style[e]=`${i(Number.parseFloat(s))}px`}))}reset(){this._resetElementAttributes(this._element,"overflow"),this._resetElementAttributes(this._element,"paddingRight"),this._resetElementAttributes(di,"paddingRight"),this._resetElementAttributes(ui,"marginRight")}_saveInitialAttribute(t,e){const i=t.style[e];i&&U.setDataAttribute(t,e,i)}_resetElementAttributes(t,e){this._applyManipulationCallback(t,(t=>{const i=U.getDataAttribute(t,e);void 0===i?t.style.removeProperty(e):(U.removeDataAttribute(t,e),t.style[e]=i)}))}_applyManipulationCallback(t,e){o(t)?e(t):V.find(t,this._element).forEach(e)}isOverflowing(){return this.getWidth()>0}}const pi={className:"modal-backdrop",isVisible:!0,isAnimated:!1,rootElement:"body",clickCallback:null},mi={className:"string",isVisible:"boolean",isAnimated:"boolean",rootElement:"(element|string)",clickCallback:"(function|null)"},gi="show",_i="mousedown.bs.backdrop";class bi{constructor(t){this._config=this._getConfig(t),this._isAppended=!1,this._element=null}show(t){this._config.isVisible?(this._append(),this._config.isAnimated&&u(this._getElement()),this._getElement().classList.add(gi),this._emulateAnimation((()=>{_(t)}))):_(t)}hide(t){this._config.isVisible?(this._getElement().classList.remove(gi),this._emulateAnimation((()=>{this.dispose(),_(t)}))):_(t)}_getElement(){if(!this._element){const t=document.createElement("div");t.className=this._config.className,this._config.isAnimated&&t.classList.add("fade"),this._element=t}return this._element}_getConfig(t){return(t={...pi,..."object"==typeof t?t:{}}).rootElement=r(t.rootElement),a("backdrop",t,mi),t}_append(){this._isAppended||(this._config.rootElement.append(this._getElement()),j.on(this._getElement(),_i,(()=>{_(this._config.clickCallback)})),this._isAppended=!0)}dispose(){this._isAppended&&(j.off(this._element,_i),this._element.remove(),this._isAppended=!1)}_emulateAnimation(t){b(t,this._getElement(),this._config.isAnimated)}}const vi={trapElement:null,autofocus:!0},yi={trapElement:"element",autofocus:"boolean"},wi=".bs.focustrap",Ei="backward";class Ai{constructor(t){this._config=this._getConfig(t),this._isActive=!1,this._lastTabNavDirection=null}activate(){const{trapElement:t,autofocus:e}=this._config;this._isActive||(e&&t.focus(),j.off(document,wi),j.on(document,"focusin.bs.focustrap",(t=>this._handleFocusin(t))),j.on(document,"keydown.tab.bs.focustrap",(t=>this._handleKeydown(t))),this._isActive=!0)}deactivate(){this._isActive&&(this._isActive=!1,j.off(document,wi))}_handleFocusin(t){const{target:e}=t,{trapElement:i}=this._config;if(e===document||e===i||i.contains(e))return;const n=V.focusableChildren(i);0===n.length?i.focus():this._lastTabNavDirection===Ei?n[n.length-1].focus():n[0].focus()}_handleKeydown(t){"Tab"===t.key&&(this._lastTabNavDirection=t.shiftKey?Ei:"forward")}_getConfig(t){return t={...vi,..."object"==typeof t?t:{}},a("focustrap",t,yi),t}}const Ti="modal",Oi="Escape",Ci={backdrop:!0,keyboard:!0,focus:!0},ki={backdrop:"(boolean|string)",keyboard:"boolean",focus:"boolean"},Li="hidden.bs.modal",xi="show.bs.modal",Di="resize.bs.modal",Si="click.dismiss.bs.modal",Ni="keydown.dismiss.bs.modal",Ii="mousedown.dismiss.bs.modal",Pi="modal-open",ji="show",Mi="modal-static";class Hi extends B{constructor(t,e){super(t),this._config=this._getConfig(e),this._dialog=V.findOne(".modal-dialog",this._element),this._backdrop=this._initializeBackDrop(),this._focustrap=this._initializeFocusTrap(),this._isShown=!1,this._ignoreBackdropClick=!1,this._isTransitioning=!1,this._scrollBar=new fi}static get Default(){return Ci}static get NAME(){return Ti}toggle(t){return this._isShown?this.hide():this.show(t)}show(t){this._isShown||this._isTransitioning||j.trigger(this._element,xi,{relatedTarget:t}).defaultPrevented||(this._isShown=!0,this._isAnimated()&&(this._isTransitioning=!0),this._scrollBar.hide(),document.body.classList.add(Pi),this._adjustDialog(),this._setEscapeEvent(),this._setResizeEvent(),j.on(this._dialog,Ii,(()=>{j.one(this._element,"mouseup.dismiss.bs.modal",(t=>{t.target===this._element&&(this._ignoreBackdropClick=!0)}))})),this._showBackdrop((()=>this._showElement(t))))}hide(){if(!this._isShown||this._isTransitioning)return;if(j.trigger(this._element,"hide.bs.modal").defaultPrevented)return;this._isShown=!1;const t=this._isAnimated();t&&(this._isTransitioning=!0),this._setEscapeEvent(),this._setResizeEvent(),this._focustrap.deactivate(),this._element.classList.remove(ji),j.off(this._element,Si),j.off(this._dialog,Ii),this._queueCallback((()=>this._hideModal()),this._element,t)}dispose(){[window,this._dialog].forEach((t=>j.off(t,".bs.modal"))),this._backdrop.dispose(),this._focustrap.deactivate(),super.dispose()}handleUpdate(){this._adjustDialog()}_initializeBackDrop(){return new bi({isVisible:Boolean(this._config.backdrop),isAnimated:this._isAnimated()})}_initializeFocusTrap(){return new Ai({trapElement:this._element})}_getConfig(t){return t={...Ci,...U.getDataAttributes(this._element),..."object"==typeof t?t:{}},a(Ti,t,ki),t}_showElement(t){const e=this._isAnimated(),i=V.findOne(".modal-body",this._dialog);this._element.parentNode&&this._element.parentNode.nodeType===Node.ELEMENT_NODE||document.body.append(this._element),this._element.style.display="block",this._element.removeAttribute("aria-hidden"),this._element.setAttribute("aria-modal",!0),this._element.setAttribute("role","dialog"),this._element.scrollTop=0,i&&(i.scrollTop=0),e&&u(this._element),this._element.classList.add(ji),this._queueCallback((()=>{this._config.focus&&this._focustrap.activate(),this._isTransitioning=!1,j.trigger(this._element,"shown.bs.modal",{relatedTarget:t})}),this._dialog,e)}_setEscapeEvent(){this._isShown?j.on(this._element,Ni,(t=>{this._config.keyboard&&t.key===Oi?(t.preventDefault(),this.hide()):this._config.keyboard||t.key!==Oi||this._triggerBackdropTransition()})):j.off(this._element,Ni)}_setResizeEvent(){this._isShown?j.on(window,Di,(()=>this._adjustDialog())):j.off(window,Di)}_hideModal(){this._element.style.display="none",this._element.setAttribute("aria-hidden",!0),this._element.removeAttribute("aria-modal"),this._element.removeAttribute("role"),this._isTransitioning=!1,this._backdrop.hide((()=>{document.body.classList.remove(Pi),this._resetAdjustments(),this._scrollBar.reset(),j.trigger(this._element,Li)}))}_showBackdrop(t){j.on(this._element,Si,(t=>{this._ignoreBackdropClick?this._ignoreBackdropClick=!1:t.target===t.currentTarget&&(!0===this._config.backdrop?this.hide():"static"===this._config.backdrop&&this._triggerBackdropTransition())})),this._backdrop.show(t)}_isAnimated(){return this._element.classList.contains("fade")}_triggerBackdropTransition(){if(j.trigger(this._element,"hidePrevented.bs.modal").defaultPrevented)return;const{classList:t,scrollHeight:e,style:i}=this._element,n=e>document.documentElement.clientHeight;!n&&"hidden"===i.overflowY||t.contains(Mi)||(n||(i.overflowY="hidden"),t.add(Mi),this._queueCallback((()=>{t.remove(Mi),n||this._queueCallback((()=>{i.overflowY=""}),this._dialog)}),this._dialog),this._element.focus())}_adjustDialog(){const t=this._element.scrollHeight>document.documentElement.clientHeight,e=this._scrollBar.getWidth(),i=e>0;(!i&&t&&!m()||i&&!t&&m())&&(this._element.style.paddingLeft=`${e}px`),(i&&!t&&!m()||!i&&t&&m())&&(this._element.style.paddingRight=`${e}px`)}_resetAdjustments(){this._element.style.paddingLeft="",this._element.style.paddingRight=""}static jQueryInterface(t,e){return this.each((function(){const i=Hi.getOrCreateInstance(this,t);if("string"==typeof t){if(void 0===i[t])throw new TypeError(`No method named "${t}"`);i[t](e)}}))}}j.on(document,"click.bs.modal.data-api",'[data-bs-toggle="modal"]',(function(t){const e=n(this);["A","AREA"].includes(this.tagName)&&t.preventDefault(),j.one(e,xi,(t=>{t.defaultPrevented||j.one(e,Li,(()=>{l(this)&&this.focus()}))}));const i=V.findOne(".modal.show");i&&Hi.getInstance(i).hide(),Hi.getOrCreateInstance(e).toggle(this)})),R(Hi),g(Hi);const Bi="offcanvas",Ri={backdrop:!0,keyboard:!0,scroll:!1},Wi={backdrop:"boolean",keyboard:"boolean",scroll:"boolean"},$i="show",zi=".offcanvas.show",qi="hidden.bs.offcanvas";class Fi extends B{constructor(t,e){super(t),this._config=this._getConfig(e),this._isShown=!1,this._backdrop=this._initializeBackDrop(),this._focustrap=this._initializeFocusTrap(),this._addEventListeners()}static get NAME(){return Bi}static get Default(){return Ri}toggle(t){return this._isShown?this.hide():this.show(t)}show(t){this._isShown||j.trigger(this._element,"show.bs.offcanvas",{relatedTarget:t}).defaultPrevented||(this._isShown=!0,this._element.style.visibility="visible",this._backdrop.show(),this._config.scroll||(new fi).hide(),this._element.removeAttribute("aria-hidden"),this._element.setAttribute("aria-modal",!0),this._element.setAttribute("role","dialog"),this._element.classList.add($i),this._queueCallback((()=>{this._config.scroll||this._focustrap.activate(),j.trigger(this._element,"shown.bs.offcanvas",{relatedTarget:t})}),this._element,!0))}hide(){this._isShown&&(j.trigger(this._element,"hide.bs.offcanvas").defaultPrevented||(this._focustrap.deactivate(),this._element.blur(),this._isShown=!1,this._element.classList.remove($i),this._backdrop.hide(),this._queueCallback((()=>{this._element.setAttribute("aria-hidden",!0),this._element.removeAttribute("aria-modal"),this._element.removeAttribute("role"),this._element.style.visibility="hidden",this._config.scroll||(new fi).reset(),j.trigger(this._element,qi)}),this._element,!0)))}dispose(){this._backdrop.dispose(),this._focustrap.deactivate(),super.dispose()}_getConfig(t){return t={...Ri,...U.getDataAttributes(this._element),..."object"==typeof t?t:{}},a(Bi,t,Wi),t}_initializeBackDrop(){return new bi({className:"offcanvas-backdrop",isVisible:this._config.backdrop,isAnimated:!0,rootElement:this._element.parentNode,clickCallback:()=>this.hide()})}_initializeFocusTrap(){return new Ai({trapElement:this._element})}_addEventListeners(){j.on(this._element,"keydown.dismiss.bs.offcanvas",(t=>{this._config.keyboard&&"Escape"===t.key&&this.hide()}))}static jQueryInterface(t){return this.each((function(){const e=Fi.getOrCreateInstance(this,t);if("string"==typeof t){if(void 0===e[t]||t.startsWith("_")||"constructor"===t)throw new TypeError(`No method named "${t}"`);e[t](this)}}))}}j.on(document,"click.bs.offcanvas.data-api",'[data-bs-toggle="offcanvas"]',(function(t){const e=n(this);if(["A","AREA"].includes(this.tagName)&&t.preventDefault(),c(this))return;j.one(e,qi,(()=>{l(this)&&this.focus()}));const i=V.findOne(zi);i&&i!==e&&Fi.getInstance(i).hide(),Fi.getOrCreateInstance(e).toggle(this)})),j.on(window,"load.bs.offcanvas.data-api",(()=>V.find(zi).forEach((t=>Fi.getOrCreateInstance(t).show())))),R(Fi),g(Fi);const Ui=new Set(["background","cite","href","itemtype","longdesc","poster","src","xlink:href"]),Vi=/^(?:(?:https?|mailto|ftp|tel|file|sms):|[^#&/:?]*(?:[#/?]|$))/i,Ki=/^data:(?:image\/(?:bmp|gif|jpeg|jpg|png|tiff|webp)|video\/(?:mpeg|mp4|ogg|webm)|audio\/(?:mp3|oga|ogg|opus));base64,[\d+/a-z]+=*$/i,Xi=(t,e)=>{const i=t.nodeName.toLowerCase();if(e.includes(i))return!Ui.has(i)||Boolean(Vi.test(t.nodeValue)||Ki.test(t.nodeValue));const n=e.filter((t=>t instanceof RegExp));for(let t=0,e=n.length;t{Xi(t,r)||i.removeAttribute(t.nodeName)}))}return n.body.innerHTML}const Qi="tooltip",Gi=new Set(["sanitize","allowList","sanitizeFn"]),Zi={animation:"boolean",template:"string",title:"(string|element|function)",trigger:"string",delay:"(number|object)",html:"boolean",selector:"(string|boolean)",placement:"(string|function)",offset:"(array|string|function)",container:"(string|element|boolean)",fallbackPlacements:"array",boundary:"(string|element)",customClass:"(string|function)",sanitize:"boolean",sanitizeFn:"(null|function)",allowList:"object",popperConfig:"(null|object|function)"},Ji={AUTO:"auto",TOP:"top",RIGHT:m()?"left":"right",BOTTOM:"bottom",LEFT:m()?"right":"left"},tn={animation:!0,template:'',trigger:"hover focus",title:"",delay:0,html:!1,selector:!1,placement:"top",offset:[0,0],container:!1,fallbackPlacements:["top","right","bottom","left"],boundary:"clippingParents",customClass:"",sanitize:!0,sanitizeFn:null,allowList:{"*":["class","dir","id","lang","role",/^aria-[\w-]*$/i],a:["target","href","title","rel"],area:[],b:[],br:[],col:[],code:[],div:[],em:[],hr:[],h1:[],h2:[],h3:[],h4:[],h5:[],h6:[],i:[],img:["src","srcset","alt","title","width","height"],li:[],ol:[],p:[],pre:[],s:[],small:[],span:[],sub:[],sup:[],strong:[],u:[],ul:[]},popperConfig:null},en={HIDE:"hide.bs.tooltip",HIDDEN:"hidden.bs.tooltip",SHOW:"show.bs.tooltip",SHOWN:"shown.bs.tooltip",INSERTED:"inserted.bs.tooltip",CLICK:"click.bs.tooltip",FOCUSIN:"focusin.bs.tooltip",FOCUSOUT:"focusout.bs.tooltip",MOUSEENTER:"mouseenter.bs.tooltip",MOUSELEAVE:"mouseleave.bs.tooltip"},nn="fade",sn="show",on="show",rn="out",an=".tooltip-inner",ln=".modal",cn="hide.bs.modal",hn="hover",dn="focus";class un extends B{constructor(t,e){if(void 0===Fe)throw new TypeError("Bootstrap's tooltips require Popper (https://popper.js.org)");super(t),this._isEnabled=!0,this._timeout=0,this._hoverState="",this._activeTrigger={},this._popper=null,this._config=this._getConfig(e),this.tip=null,this._setListeners()}static get Default(){return tn}static get NAME(){return Qi}static get Event(){return en}static get DefaultType(){return Zi}enable(){this._isEnabled=!0}disable(){this._isEnabled=!1}toggleEnabled(){this._isEnabled=!this._isEnabled}toggle(t){if(this._isEnabled)if(t){const e=this._initializeOnDelegatedTarget(t);e._activeTrigger.click=!e._activeTrigger.click,e._isWithActiveTrigger()?e._enter(null,e):e._leave(null,e)}else{if(this.getTipElement().classList.contains(sn))return void this._leave(null,this);this._enter(null,this)}}dispose(){clearTimeout(this._timeout),j.off(this._element.closest(ln),cn,this._hideModalHandler),this.tip&&this.tip.remove(),this._disposePopper(),super.dispose()}show(){if("none"===this._element.style.display)throw new Error("Please use show on visible elements");if(!this.isWithContent()||!this._isEnabled)return;const t=j.trigger(this._element,this.constructor.Event.SHOW),e=h(this._element),i=null===e?this._element.ownerDocument.documentElement.contains(this._element):e.contains(this._element);if(t.defaultPrevented||!i)return;"tooltip"===this.constructor.NAME&&this.tip&&this.getTitle()!==this.tip.querySelector(an).innerHTML&&(this._disposePopper(),this.tip.remove(),this.tip=null);const n=this.getTipElement(),s=(t=>{do{t+=Math.floor(1e6*Math.random())}while(document.getElementById(t));return t})(this.constructor.NAME);n.setAttribute("id",s),this._element.setAttribute("aria-describedby",s),this._config.animation&&n.classList.add(nn);const o="function"==typeof this._config.placement?this._config.placement.call(this,n,this._element):this._config.placement,r=this._getAttachment(o);this._addAttachmentClass(r);const{container:a}=this._config;H.set(n,this.constructor.DATA_KEY,this),this._element.ownerDocument.documentElement.contains(this.tip)||(a.append(n),j.trigger(this._element,this.constructor.Event.INSERTED)),this._popper?this._popper.update():this._popper=qe(this._element,n,this._getPopperConfig(r)),n.classList.add(sn);const l=this._resolvePossibleFunction(this._config.customClass);l&&n.classList.add(...l.split(" ")),"ontouchstart"in document.documentElement&&[].concat(...document.body.children).forEach((t=>{j.on(t,"mouseover",d)}));const c=this.tip.classList.contains(nn);this._queueCallback((()=>{const t=this._hoverState;this._hoverState=null,j.trigger(this._element,this.constructor.Event.SHOWN),t===rn&&this._leave(null,this)}),this.tip,c)}hide(){if(!this._popper)return;const t=this.getTipElement();if(j.trigger(this._element,this.constructor.Event.HIDE).defaultPrevented)return;t.classList.remove(sn),"ontouchstart"in document.documentElement&&[].concat(...document.body.children).forEach((t=>j.off(t,"mouseover",d))),this._activeTrigger.click=!1,this._activeTrigger.focus=!1,this._activeTrigger.hover=!1;const e=this.tip.classList.contains(nn);this._queueCallback((()=>{this._isWithActiveTrigger()||(this._hoverState!==on&&t.remove(),this._cleanTipClass(),this._element.removeAttribute("aria-describedby"),j.trigger(this._element,this.constructor.Event.HIDDEN),this._disposePopper())}),this.tip,e),this._hoverState=""}update(){null!==this._popper&&this._popper.update()}isWithContent(){return Boolean(this.getTitle())}getTipElement(){if(this.tip)return this.tip;const t=document.createElement("div");t.innerHTML=this._config.template;const e=t.children[0];return this.setContent(e),e.classList.remove(nn,sn),this.tip=e,this.tip}setContent(t){this._sanitizeAndSetContent(t,this.getTitle(),an)}_sanitizeAndSetContent(t,e,i){const n=V.findOne(i,t);e||!n?this.setElementContent(n,e):n.remove()}setElementContent(t,e){if(null!==t)return o(e)?(e=r(e),void(this._config.html?e.parentNode!==t&&(t.innerHTML="",t.append(e)):t.textContent=e.textContent)):void(this._config.html?(this._config.sanitize&&(e=Yi(e,this._config.allowList,this._config.sanitizeFn)),t.innerHTML=e):t.textContent=e)}getTitle(){const t=this._element.getAttribute("data-bs-original-title")||this._config.title;return this._resolvePossibleFunction(t)}updateAttachment(t){return"right"===t?"end":"left"===t?"start":t}_initializeOnDelegatedTarget(t,e){return e||this.constructor.getOrCreateInstance(t.delegateTarget,this._getDelegateConfig())}_getOffset(){const{offset:t}=this._config;return"string"==typeof t?t.split(",").map((t=>Number.parseInt(t,10))):"function"==typeof t?e=>t(e,this._element):t}_resolvePossibleFunction(t){return"function"==typeof t?t.call(this._element):t}_getPopperConfig(t){const e={placement:t,modifiers:[{name:"flip",options:{fallbackPlacements:this._config.fallbackPlacements}},{name:"offset",options:{offset:this._getOffset()}},{name:"preventOverflow",options:{boundary:this._config.boundary}},{name:"arrow",options:{element:`.${this.constructor.NAME}-arrow`}},{name:"onChange",enabled:!0,phase:"afterWrite",fn:t=>this._handlePopperPlacementChange(t)}],onFirstUpdate:t=>{t.options.placement!==t.placement&&this._handlePopperPlacementChange(t)}};return{...e,..."function"==typeof this._config.popperConfig?this._config.popperConfig(e):this._config.popperConfig}}_addAttachmentClass(t){this.getTipElement().classList.add(`${this._getBasicClassPrefix()}-${this.updateAttachment(t)}`)}_getAttachment(t){return Ji[t.toUpperCase()]}_setListeners(){this._config.trigger.split(" ").forEach((t=>{if("click"===t)j.on(this._element,this.constructor.Event.CLICK,this._config.selector,(t=>this.toggle(t)));else if("manual"!==t){const e=t===hn?this.constructor.Event.MOUSEENTER:this.constructor.Event.FOCUSIN,i=t===hn?this.constructor.Event.MOUSELEAVE:this.constructor.Event.FOCUSOUT;j.on(this._element,e,this._config.selector,(t=>this._enter(t))),j.on(this._element,i,this._config.selector,(t=>this._leave(t)))}})),this._hideModalHandler=()=>{this._element&&this.hide()},j.on(this._element.closest(ln),cn,this._hideModalHandler),this._config.selector?this._config={...this._config,trigger:"manual",selector:""}:this._fixTitle()}_fixTitle(){const t=this._element.getAttribute("title"),e=typeof this._element.getAttribute("data-bs-original-title");(t||"string"!==e)&&(this._element.setAttribute("data-bs-original-title",t||""),!t||this._element.getAttribute("aria-label")||this._element.textContent||this._element.setAttribute("aria-label",t),this._element.setAttribute("title",""))}_enter(t,e){e=this._initializeOnDelegatedTarget(t,e),t&&(e._activeTrigger["focusin"===t.type?dn:hn]=!0),e.getTipElement().classList.contains(sn)||e._hoverState===on?e._hoverState=on:(clearTimeout(e._timeout),e._hoverState=on,e._config.delay&&e._config.delay.show?e._timeout=setTimeout((()=>{e._hoverState===on&&e.show()}),e._config.delay.show):e.show())}_leave(t,e){e=this._initializeOnDelegatedTarget(t,e),t&&(e._activeTrigger["focusout"===t.type?dn:hn]=e._element.contains(t.relatedTarget)),e._isWithActiveTrigger()||(clearTimeout(e._timeout),e._hoverState=rn,e._config.delay&&e._config.delay.hide?e._timeout=setTimeout((()=>{e._hoverState===rn&&e.hide()}),e._config.delay.hide):e.hide())}_isWithActiveTrigger(){for(const t in this._activeTrigger)if(this._activeTrigger[t])return!0;return!1}_getConfig(t){const e=U.getDataAttributes(this._element);return Object.keys(e).forEach((t=>{Gi.has(t)&&delete e[t]})),(t={...this.constructor.Default,...e,..."object"==typeof t&&t?t:{}}).container=!1===t.container?document.body:r(t.container),"number"==typeof t.delay&&(t.delay={show:t.delay,hide:t.delay}),"number"==typeof t.title&&(t.title=t.title.toString()),"number"==typeof t.content&&(t.content=t.content.toString()),a(Qi,t,this.constructor.DefaultType),t.sanitize&&(t.template=Yi(t.template,t.allowList,t.sanitizeFn)),t}_getDelegateConfig(){const t={};for(const e in this._config)this.constructor.Default[e]!==this._config[e]&&(t[e]=this._config[e]);return t}_cleanTipClass(){const t=this.getTipElement(),e=new RegExp(`(^|\\s)${this._getBasicClassPrefix()}\\S+`,"g"),i=t.getAttribute("class").match(e);null!==i&&i.length>0&&i.map((t=>t.trim())).forEach((e=>t.classList.remove(e)))}_getBasicClassPrefix(){return"bs-tooltip"}_handlePopperPlacementChange(t){const{state:e}=t;e&&(this.tip=e.elements.popper,this._cleanTipClass(),this._addAttachmentClass(this._getAttachment(e.placement)))}_disposePopper(){this._popper&&(this._popper.destroy(),this._popper=null)}static jQueryInterface(t){return this.each((function(){const e=un.getOrCreateInstance(this,t);if("string"==typeof t){if(void 0===e[t])throw new TypeError(`No method named "${t}"`);e[t]()}}))}}g(un);const 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index 0bba767..0000000 --- a/vignettes/adrg-quarto_files/libs/quarto-html/quarto-syntax-highlighting.css +++ /dev/null @@ -1,167 +0,0 @@ -/* quarto syntax highlight colors */ -:root { - --quarto-hl-ot-color: #003B4F; - --quarto-hl-at-color: #657422; - --quarto-hl-ss-color: #20794D; - --quarto-hl-an-color: #5E5E5E; - --quarto-hl-fu-color: #4758AB; - --quarto-hl-st-color: #20794D; - --quarto-hl-cf-color: #003B4F; - --quarto-hl-op-color: #5E5E5E; - --quarto-hl-er-color: #AD0000; - --quarto-hl-bn-color: #AD0000; - --quarto-hl-al-color: #AD0000; - --quarto-hl-va-color: #111111; - --quarto-hl-bu-color: inherit; - --quarto-hl-ex-color: inherit; - --quarto-hl-pp-color: #AD0000; - --quarto-hl-in-color: #5E5E5E; - --quarto-hl-vs-color: #20794D; - --quarto-hl-wa-color: #5E5E5E; - --quarto-hl-do-color: #5E5E5E; - --quarto-hl-im-color: #00769E; - --quarto-hl-ch-color: #20794D; - --quarto-hl-dt-color: #AD0000; - --quarto-hl-fl-color: #AD0000; - --quarto-hl-co-color: #5E5E5E; - --quarto-hl-cv-color: #5E5E5E; - --quarto-hl-cn-color: #8f5902; - --quarto-hl-sc-color: #5E5E5E; - --quarto-hl-dv-color: #AD0000; - --quarto-hl-kw-color: #003B4F; -} - -/* other quarto variables */ -:root { - --quarto-font-monospace: SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace; -} - -code span { - color: #003B4F; -} - -code.sourceCode > span { - color: #003B4F; -} - -div.sourceCode, -div.sourceCode pre.sourceCode { - color: #003B4F; -} - -code span.ot { - color: #003B4F; -} - -code span.at { - color: #657422; -} - -code span.ss { - color: #20794D; -} - -code span.an { - color: #5E5E5E; -} - -code span.fu { - color: #4758AB; -} - -code span.st { - color: #20794D; -} - -code span.cf { - color: #003B4F; -} - -code span.op { - color: #5E5E5E; -} - -code span.er { - color: #AD0000; -} - -code span.bn { - color: #AD0000; -} - -code span.al { - color: #AD0000; -} - -code span.va { - color: #111111; -} - -code span.pp { - color: #AD0000; -} - -code span.in { - color: 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true, true); - window.document.dispatchEvent(event); - } - const tabs = window.document.querySelectorAll('a[data-bs-toggle="tab"]'); - tabs.forEach((tab) => { - tab.addEventListener("shown.bs.tab", fireSlideEnter); - }); - - // Track scrolling and mark TOC links as active - // get table of contents and sidebar (bail if we don't have at least one) - const tocLinks = tocEl - ? [...tocEl.querySelectorAll("a[data-scroll-target]")] - : []; - const makeActive = (link) => tocLinks[link].classList.add("active"); - const removeActive = (link) => tocLinks[link].classList.remove("active"); - const removeAllActive = () => - [...Array(tocLinks.length).keys()].forEach((link) => removeActive(link)); - - // activate the anchor for a section associated with this TOC entry - tocLinks.forEach((link) => { - link.addEventListener("click", () => { - if (link.href.indexOf("#") !== -1) { - const anchor = link.href.split("#")[1]; - const heading = window.document.querySelector( - `[data-anchor-id=${anchor}]` - ); - if (heading) { - // Add the class - heading.classList.add("reveal-anchorjs-link"); - - // function to show the anchor - const handleMouseout = () => { - heading.classList.remove("reveal-anchorjs-link"); - heading.removeEventListener("mouseout", handleMouseout); - }; - - // add a function to clear the anchor when the user mouses out of it - heading.addEventListener("mouseout", handleMouseout); - } - } - }); - }); - - const sections = tocLinks.map((link) => { - const target = link.getAttribute("data-scroll-target"); - if (target.startsWith("#")) { - return window.document.getElementById(decodeURI(`${target.slice(1)}`)); - } else { - return window.document.querySelector(decodeURI(`${target}`)); - } - }); - - const sectionMargin = 200; - let currentActive = 0; - // track whether we've initialized state the first time - let init = false; - - const updateActiveLink = () => { - // The index from bottom to top (e.g. reversed list) - let sectionIndex = -1; - if ( - window.innerHeight + window.pageYOffset >= - window.document.body.offsetHeight - ) { - sectionIndex = 0; - } else { - sectionIndex = [...sections].reverse().findIndex((section) => { - if (section) { - return window.pageYOffset >= section.offsetTop - sectionMargin; - } else { - return false; - } - }); - } - if (sectionIndex > -1) { - const current = sections.length - sectionIndex - 1; - if (current !== currentActive) { - removeAllActive(); - currentActive = current; - makeActive(current); - if (init) { - window.dispatchEvent(sectionChanged); - } - init = true; - } - } - }; - - const inHiddenRegion = (top, bottom, hiddenRegions) => { - for (const region of hiddenRegions) { - if (top <= region.bottom && bottom >= region.top) { - return true; - } - } - return false; - }; - - const categorySelector = "header.quarto-title-block .quarto-category"; - const activateCategories = (href) => { - // Find any categories - // Surround them with a link pointing back to: - // #category=Authoring - try { - const categoryEls = window.document.querySelectorAll(categorySelector); - for (const categoryEl of categoryEls) { - const categoryText = categoryEl.textContent; - if (categoryText) { - const link = `${href}#category=${encodeURIComponent(categoryText)}`; - const linkEl = window.document.createElement("a"); - linkEl.setAttribute("href", link); - for (const child of categoryEl.childNodes) { - linkEl.append(child); - } - categoryEl.appendChild(linkEl); - } - } - } catch { - // Ignore errors - } - }; - function hasTitleCategories() { - return window.document.querySelector(categorySelector) !== null; - } - - function offsetRelativeUrl(url) { - const offset = getMeta("quarto:offset"); - return offset ? offset + url : url; - } - - function offsetAbsoluteUrl(url) { - const offset = getMeta("quarto:offset"); - const baseUrl = new URL(offset, window.location); - - const projRelativeUrl = url.replace(baseUrl, ""); - if (projRelativeUrl.startsWith("/")) { - return projRelativeUrl; - } else { - return "/" + projRelativeUrl; - } - } - - // read a meta tag value - function getMeta(metaName) { - const metas = window.document.getElementsByTagName("meta"); - for (let i = 0; i < metas.length; i++) { - if (metas[i].getAttribute("name") === metaName) { - return metas[i].getAttribute("content"); - } - } - return ""; - } - - async function findAndActivateCategories() { - const currentPagePath = offsetAbsoluteUrl(window.location.href); - const response = await fetch(offsetRelativeUrl("listings.json")); - if (response.status == 200) { - return response.json().then(function (listingPaths) { - const listingHrefs = []; - for (const listingPath of listingPaths) { - const pathWithoutLeadingSlash = listingPath.listing.substring(1); - for (const item of listingPath.items) { - if ( - item === currentPagePath || - item === currentPagePath + "index.html" - ) { - // Resolve this path against the offset to be sure - // we already are using the correct path to the listing - // (this adjusts the listing urls to be rooted against - // whatever root the page is actually running against) - const relative = offsetRelativeUrl(pathWithoutLeadingSlash); - const baseUrl = window.location; - const resolvedPath = new URL(relative, baseUrl); - listingHrefs.push(resolvedPath.pathname); - break; - } - } - } - - // Look up the tree for a nearby linting and use that if we find 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toggleContents.style.height = "0px"; - tocShowing = false; - } - }; - - const positionToggle = () => { - // position the element (top left of parent, same width as parent) - const elRect = el.getBoundingClientRect(); - toggleContainer.style.left = `${elRect.left}px`; - toggleContainer.style.top = `${elRect.top}px`; - toggleContainer.style.width = `${elRect.width}px`; - }; - - // Get rid of any expanded toggle if the user scrolls - window.document.addEventListener( - "scroll", - throttle(() => { - closeToggle(); - }, 50) - ); - - // Handle positioning of the toggle - window.addEventListener( - "resize", - throttle(() => { - positionToggle(); - }, 50) - ); - positionToggle(); - - // Process the click - clickEl.onclick = () => { - if (!tocShowing) { - toggleContainer.classList.add("expanded"); - toggleContents.style.height = null; - tocShowing = true; - } else { - closeToggle(); - } - }; - }; - - // Converts a sidebar from a menu back to a sidebar - const convertToSidebar = () => { - for 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d1f9425..9f79b63 100644 --- a/vignettes/cover-letter.Rmd +++ b/vignettes/cover-letter.Rmd @@ -3,7 +3,7 @@ title: "R Consortium R Submission Pilot 2 Cover Letter" author: "Eric Nantz" output: pagedown::html_letter: - self_contained: false + self_contained: true links-to-footnotes: true paged-footnotes: true # uncomment this line to produce HTML and PDF in RStudio: @@ -50,7 +50,7 @@ This letter serves as an introduction to the R Consortium R submission Pilot 2. The R Consortium R submission Pilot 2 submission package follows the eCTD folder structure and contains the following module 5 deliverables: - A cover letter -- SAS transport files (xpt) from CDIS ADaM/SDTM submission pilot CDISCPILOT01 +- SAS transport files (xpt) from CDISC ADaM/SDTM submission pilot CDISCPILOT01 - One proprietary R package "pilot2wrappers" which enables execution of the Shiny application - An Analysis Data Reviewer's Guide (ADRG) @@ -60,7 +60,7 @@ In this pilot, we aimed to provide a working example of R submission in eCTD for - Reconstruct and load the submitted proprietary R package (i.e. "pilot2wrappers") - Install and load open source packages used in this submission - Execute the Shiny application within an R session -- Share potential improvements to the submission deliverables and processes via a written communications +- Share potential improvements to the submission deliverables and processes via a written communication All data, code, material and communications from this pilot will be shared publicly. @@ -69,4 +69,5 @@ Different open-source packages were used to create the Shiny application. Evalua On behalf of the R Consortium R Submission Working Group, we hope the pilot 2 project can establish a working example to guide the industry for future submission of Shiny applications created with the R language. Kind regards, + The R Consortium R Submission Pilot 2 Project Team diff --git a/vignettes/cover-letter.pdf b/vignettes/cover-letter.pdf deleted file mode 100644 index d4a1add..0000000 Binary files a/vignettes/cover-letter.pdf and /dev/null differ diff --git a/vignettes/ectd/r1pkg.txt b/vignettes/ectd/r1pkg.txt index 189ded5..221fbd8 100644 --- a/vignettes/ectd/r1pkg.txt +++ b/vignettes/ectd/r1pkg.txt @@ -50,7 +50,7 @@ Content: Package: pilot2wrappers Type: Package Title: R Consortium R Submission Pilot 2 - Version: 0.3.0 + Version: 0.4.0 Authors@R: c( person("Eric", "Nantz", email = "theRcast@gmail.com", role = c("aut", "cre")), person("Yilong", "Zhang", role = c("aut")), @@ -61,7 +61,7 @@ Content: person("copyright", role = c("cph")) ) Description: Insert Package Description. - Depends: R (>= 3.6.0) + Depends: R (>= 4.1.0) License: GPL (>= 3) Imports: config (>= 0.3.1), @@ -93,8 +93,7 @@ Content: devtools, testthat, knitr, - rmarkdown, - covr + rmarkdown Encoding: UTF-8 LazyData: true Roxygen: list(markdown = TRUE) @@ -176,18 +175,24 @@ Package: pilot2wrappers File: NEWS.md Format: text Content: - # pilot2 0.3.0 + # pilot2wrappers 0.4.0 + + - Ensure column width of efficacy table's 95% CI header is wide enough to fit in a single row + - Add missing footnotes to primary table + - Add new vignettes for ADRG as a [Quarto](https://quarto.org/) document (with HTML and PDF output) and cover letter as a R-Markdown document using the [`{pagedown}`](https://pagedown.rbind.io/#letter) package. + + # pilot2wrappers 0.3.0 - Enable support for using `{pkglite}` to create package bundle compliant with ECTD submission transfer standards - Fix display of tooltips in select modules by using the `{tippy}` R package - Add helper function `set_data_path` for the user to set the directory path to `.xpt` data files loaded into the application - # pilot2 0.2.0 + # pilot2wrappers 0.2.0 - Convert Shiny application to a package structure using [`{golem}`](https://thinkr-open.github.io/golem). - Incorporate the open-source [`{teal}`](https://insightsengineering.github.io/teal/main) package inside application to provide dynamic filters in all modules - # pilot2 0.1.0 + # pilot2wrappers 0.1.0 - Initial version. - Added a `NEWS.md` file to track changes to the package. @@ -208,17 +213,27 @@ Content: ## Overview + The objective of the R Consortium R submission Pilot 2 Project is to test the concept that a Shiny application created with the R-language can be successfully bundled into a submission package and transferred successfully to FDA reviewers. The application was built using the source data sets and analyses contained in the R submission Pilot 1 Project, with materials available on the [RConsortium/submissions-pilot1](https://github.com/RConsortium/submissions-pilot1) repository, All submission materials and communications from this pilot are publicly available, with the aim of providing a working example for future R language based FDA submissions. This is a FDA-industry collaboration through the non-profit organization R consortium. + + While the intent of the project is to enable execution of the Shiny application in a reviewer's local R environment, a deployed version of the application is available in open access through the Shinyapps.io service at [rconsortium.shinyapps.io/submissions-pilot2](https://rconsortium.shinyapps.io/submissions-pilot2/). + + The [working group website](https://rconsortium.github.io/submissions-wg/). + + The [RConsortium/submissions-pilot2](https://github.com/RConsortium/submissions-pilot2) demonstrates an approach to organize a Shiny application as an R package. + + The [RConsortium/submissions-pilot2-to-fda](https://github.com/RConsortium/submissions-pilot2-to-fda) + repo demonstrates the eCTD submission package based on the [RConsortium/submissions-pilot2](https://github.com/RConsortium/submissions-pilot2) repo. + ## Meeting Minutes - [Repo wiki](https://github.com/RConsortium/submissions-pilot2/wiki) + [Repo wiki](https://github.com/RConsortium/submissions-pilot2/wiki) ## Installing `teal` : + Follow the link [here](https://github.com/insightsengineering/depository#readme) ## Running application - More instructions to come, but you can run the app by doing the following: - * Clone this repository to your local machine * Open the project within RStudio, and run `renv::restore()` if prompted to restore the `{renv}` package library * Open the `app.R` script and run the application within RStudio by clicking the Run App button @@ -253,7 +268,7 @@ Format: text Content: default: golem_name: pilot2wrappers - golem_version: 0.0.0.9000 + golem_version: 0.4.0 app_prod: no adam_path: "datasets/adam" production: @@ -1109,7 +1124,7 @@ Content: tags$br(), tags$hr(), fluidRow( - h6(tags$i("*Abbreviation: CI=Confidence Interval; LS=Least Squarses; SD=Standard Deviation")) + h6(tags$i("Abbreviations: CI=Confidence Interval; LS=Least Squarses; SD=Standard Deviation")) ) ) } @@ -1196,10 +1211,12 @@ Content: "N","Mean (SD)", "N","Mean (SD)","LS Mean (95% CI)") colgr=c(1,2,2,3,3,4,4,4) + colwidths <- c(rep(100, 7), 150) colgrn=c("","Baseline","Week 20","Change from Baseline") - collist = lapply(1:ncol(apr0ancova1),function(xx) colDef(name=coln[xx])) + collist = purrr::map2(1:ncol(apr0ancova1), colwidths, ~{ + colDef(name = coln[.x], minWidth = .y) + }) names(collist) = names(apr0ancova1) - reactable( apr0ancova1, columns = collist, @@ -1246,7 +1263,12 @@ Content: #' @importFrom shiny NS tagList uiOutput ui_t_primary <- function(id, datasets) { ns <- NS(id) - uiOutput(ns("table")) + tagList( + uiOutput(ns("table")), + p("[1] Based on Analysis of covariance (ANCOVA) model with treatment and site group as factors and baseline value as a covariate."), + p("[2] Test for a non-zero coefficient for treatment (dose) as a continuous variable."), + p("[3] Pairwise comparison with treatment as a categorical variable: p-values without adjustment for multiple comparisons.") + ) } #' srv_t_primary Server Functions