diff --git a/geometry/render_gltf_client/test/integration_test.py b/geometry/render_gltf_client/test/integration_test.py
index 1554b6a8e33c..c3332af5f706 100644
--- a/geometry/render_gltf_client/test/integration_test.py
+++ b/geometry/render_gltf_client/test/integration_test.py
@@ -35,6 +35,11 @@
 LABEL_PIXEL_THRESHOLD = 0
 INVALID_PIXEL_FRACTION = 0.2
 
+# TODO(#19305) Remove this once the skipped tests reliably pass on macOS.
+_SKIP = False
+if "darwin" in sys.platform:
+    _SKIP = True
+
 
 class TestIntegration(unittest.TestCase):
     def setUp(self):
@@ -215,6 +220,7 @@ def _check_one_gltf(self, gltf, ground_truth_gltf):
         # normalization, e.g., meshes, cameras, materials, accessors, etc.
         self.assertCountEqual(actual["nodes"], expected["nodes"])
 
+    @unittest.skipIf(_SKIP, "Skipped on macOS, see #19305")
     def test_integration(self):
         """Quantitatively compares the images rendered by RenderEngineVtk and
         RenderEngineGltfClient via a fully exercised RPC pipeline.
@@ -260,6 +266,7 @@ def test_integration(self):
             )
             self.assert_error_fraction_less(label_diff, INVALID_PIXEL_FRACTION)
 
+    @unittest.skipIf(_SKIP, "Skipped on macOS, see #19305")
     def test_gltf_conversion(self):
         """Checks that the fundamental structure of the generated glTF files is
         preserved.  The comparison of the exact texture information is not in