diff --git a/src/systems/diffeqs/abstractodesystem.jl b/src/systems/diffeqs/abstractodesystem.jl
index 13b5750228..b33df83989 100644
--- a/src/systems/diffeqs/abstractodesystem.jl
+++ b/src/systems/diffeqs/abstractodesystem.jl
@@ -829,7 +829,8 @@ function process_DEProblem(constructor, sys::AbstractODESystem, u0map, parammap;
     end
 
     if has_index_cache(sys) && get_index_cache(sys) !== nothing
-        u0, defs = get_u0(sys, trueinit, parammap; symbolic_u0, t0 = t)
+        u0, defs = get_u0(sys, trueinit, parammap; symbolic_u0,
+            t0 = constructor <: Union{DDEFunction, SDDEFunction} ? nothing : t)
         check_eqs_u0(eqs, dvs, u0; kwargs...)
         p = if parammap === nothing ||
                parammap == SciMLBase.NullParameters() && isempty(defs)
@@ -843,7 +844,7 @@ function process_DEProblem(constructor, sys::AbstractODESystem, u0map, parammap;
             parammap;
             tofloat,
             use_union,
-            t0 = t,
+            t0 = constructor <: Union{DDEFunction, SDDEFunction} ? nothing : t,
             symbolic_u0)
         p, split_idxs = split_parameters_by_type(p)
         if p isa Tuple