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software.html
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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<meta name="keywords" content="washington university st louis, washington university st. louis, washington university, st. louis, wash u, ben major, wnt, wnt pathway, major lab, major lab wash u, major" />
<meta name="description" content="The Major lab utilizes mass spectrometry and other biochemical and bioinformatic techniques to elucidate signal transduction within the Wnt/B-catenin and Keap1/Nrf2 pathways." />
<link rel="stylesheet" type="text/css" href="css/normalize.css" />
<link rel="stylesheet" type="text/css" href="css/main.css" />
<link rel="shortcut icon" type="image/x-icon" href="img/branding/wu_icon.png" />
<title>Major Lab - Software</title>
<script src="js/jquery-3.5.1.min.js"></script>
<script type="text/javascript" src="js/google-analytics.js"></script>
</head>
<body>
<div id="wrap">
<div id="stripe1">
<!-- will load common navbar with js $().load() method -->
</div>
<div id="stripe2">
<div id="str2">
<div class="innerdiv">
<div class="pageHeader">
<h1>Software</h1>
</div>
<div class="content">
<div>
<a href="https://github.com/UNC-Major-Lab/" target="_blank">
<img src="img/branding/GitHub_Logo.png" alt="GitHub" width="100" height="42" border="0">
</a>
</div>
<!-- spotlite -->
<div class="software-content">
<div class="software-container spotlite" onclick="window.open('https://lbgsites2.bioinf.unc.edu/spotlite','new_window');" style="cursor: pointer;">
<div class="software-img">
<img src="img/software/spotlite_software.png" alt="Spotlite"/>
</div>
<div class="software-desc">
<p class="software-title">Spotlite: A web server for predicting co-complexed proteins from affinity purification – mass spectrometry data
</p>
<p>
Spotlite is a user-friendly web application for predicting complex co-membership from affinity purification - mass spectrometry data. This web application employs a logistic regression classifier that integrates existing, proven APMS scoring approaches (SAINT, CompPASS, and HGSCore), gene co-expression patterns, functional annotations, domain-domain binding affinity, and homologous interactions, which we have shown outperforms existing APMS scoring methods. Spotlite can be access <a href="https://lbgsites2.bioinf.unc.edu/spotlite" target="_blank">here</a>.
</p>
</div>
<!--<div common="clear:both"/>-->
</div>
<!-- MSAcquisitionSimulator -->
<div class="software-container MSAcquisitionSimulator" onclick="window.open('https://github.com/UNC-Major-Lab/MSAcquisitionSimulator/','new_window');" style="cursor: pointer;">
<div class="software-img">
<img src="img/software/MSAcquisitionSimulator_software.png" alt="MSAcquisitionSimulator"/>
</div>
<div class="software-desc">
<p class="software-title">MSAcquisitionSimulator: data-dependent acquisition simulator for LC-MS shotgun proteomics
</p>
<p>
MSAcquisitionSimulator is a collection of three command-line tools written in C++ that simulate ground truth LC-MS data and the subsequent application of custom data-dependent acquisition (DDA) algorithms. It provides an opportunity for researchers to test, refine, and evaluate novel DDA algorithms prior to implementation on a mass spectrometer. The project and source code is hosted on <a href="https://github.com/UNC-Major-Lab/MSAcquisitionSimulator/" target="_blank">GitHub</a>.
</p>
</div>
<!--<div common="clear:both"/>-->
</div>
</div>
</div>
</div>
</div>
</div>
</div>
<div id="footer">
<!-- will load common footer with js $().load() method -->
</div>
<script src="js/mainFunctions.js"></script>
</body>
</html>