diff --git a/python/nav/alertengine/dispatchers/sms_dispatcher.py b/python/nav/alertengine/dispatchers/sms_dispatcher.py
index 374d1df439..15d3c14f5e 100644
--- a/python/nav/alertengine/dispatchers/sms_dispatcher.py
+++ b/python/nav/alertengine/dispatchers/sms_dispatcher.py
@@ -73,6 +73,4 @@ def get_fallback_message(self, alert, language, message_type):
 
     @staticmethod
     def is_valid_address(address):
-        if address.startswith("+"):
-            return address[1:].isdigit()
-        return address.isdigit()
+        return address.removeprefix("+").isdigit()
diff --git a/python/nav/bin/navmain.py b/python/nav/bin/navmain.py
index b69c5bce93..44fde7bab5 100755
--- a/python/nav/bin/navmain.py
+++ b/python/nav/bin/navmain.py
@@ -214,7 +214,7 @@ def _service_printer(service):
 
         kind = service.__class__.__name__
         if kind.endswith("Service"):
-            kind = kind[:-7].lower()
+            kind = kind.removesuffix("Service").lower()
         kind = "({})".format(kind)
         kind = "{:>8}".format(kind)
         colors.print_color(kind, colors.COLOR_YELLOW, newline=False)
diff --git a/python/nav/django/validators.py b/python/nav/django/validators.py
index 7a73d3f692..ed800d8cbb 100644
--- a/python/nav/django/validators.py
+++ b/python/nav/django/validators.py
@@ -26,8 +26,7 @@
 
 def is_valid_point_string(point_string):
     if len(point_string.split(',')) == 2:
-        if point_string.startswith('(') and point_string.endswith(')'):
-            point_string = point_string[1:-1]
+        point_string = point_string.removeprefix("(").removesuffix(")")
         x_point, y_point = point_string.split(',')
         try:
             Decimal(x_point.strip())
diff --git a/python/nav/ipdevpoll/config.py b/python/nav/ipdevpoll/config.py
index 5bb8dc1bf5..ba725bf76e 100644
--- a/python/nav/ipdevpoll/config.py
+++ b/python/nav/ipdevpoll/config.py
@@ -146,7 +146,7 @@ def __init__(self, name, interval, intensity, plugins, description=''):
     def from_config_section(cls, config, section):
         """Creates a JobDescriptor from a ConfigParser section"""
         if section.startswith(JOB_PREFIX):
-            jobname = section[len(JOB_PREFIX) :]
+            jobname = section.removeprefix(JOB_PREFIX)
         else:
             raise InvalidJobSectionName(section)
 
diff --git a/python/nav/ipdevpoll/log.py b/python/nav/ipdevpoll/log.py
index 91d0a76c4a..7cca2cce5a 100644
--- a/python/nav/ipdevpoll/log.py
+++ b/python/nav/ipdevpoll/log.py
@@ -45,7 +45,7 @@ def __init__(self, pidlog=False):
     def format(self, record):
         """Overridden to choose format based on record contents."""
         self._set_context(record)
-        self._strip_logger_prefix(record)
+        record.name = record.name.removeprefix(self.prefix)
         return Formatter.format(self, record)
 
     def _set_context(self, record):
@@ -64,10 +64,6 @@ def _set_format(self, fmt):
         self._fmt = fmt
         self._style._fmt = fmt
 
-    def _strip_logger_prefix(self, record):
-        if record.name.startswith(self.prefix):
-            record.name = record.name[len(self.prefix) :]
-
 
 # pylint: disable=R0903
 class ContextLogger(object):
diff --git a/python/nav/ipdevpoll/plugins/dot1q.py b/python/nav/ipdevpoll/plugins/dot1q.py
index 1391303b2c..fe07d2e703 100644
--- a/python/nav/ipdevpoll/plugins/dot1q.py
+++ b/python/nav/ipdevpoll/plugins/dot1q.py
@@ -172,8 +172,7 @@ def _get_vlan_names(self):
             for vlannum, name in names.items():
                 vlannum = self._remap_vlan(vlannum)
                 suffix = '+{}'.format(vlannum)
-                if name.endswith(suffix):
-                    name = name[: -len(suffix)]
+                name = name.removesuffix(suffix)
                 vlan = self.containers.factory(name, shadows.Vlan)
                 vlan.net_type = shadows.NetType.get('lan')
                 vlan.vlan = vlannum
diff --git a/python/nav/ipdevpoll/plugins/prefix.py b/python/nav/ipdevpoll/plugins/prefix.py
index b26b665775..2f8d88a629 100644
--- a/python/nav/ipdevpoll/plugins/prefix.py
+++ b/python/nav/ipdevpoll/plugins/prefix.py
@@ -264,7 +264,7 @@ def __init__(self, string):
         for oper in self.OPERATORS:
             if string.startswith(oper):
                 self.match_operator = oper
-                string = string[len(oper) :]
+                string = string.removeprefix(oper)
                 break
 
         IP.__init__(self, string)  # stupid old-style class implementation!
diff --git a/python/nav/models/fields.py b/python/nav/models/fields.py
index 6efc77f7b2..6fd5a54803 100644
--- a/python/nav/models/fields.py
+++ b/python/nav/models/fields.py
@@ -128,14 +128,10 @@ def from_db_value(self, value, expression, connection):
     def to_python(self, value):
         if not value or isinstance(value, tuple):
             return value
-        if isinstance(value, str):
-            if validators.is_valid_point_string(value):
-                if value.startswith('(') and value.endswith(')'):
-                    noparens = value[1:-1]
-                else:
-                    noparens = value
-                latitude, longitude = noparens.split(',')
-                return (Decimal(latitude.strip()), Decimal(longitude.strip()))
+        if isinstance(value, str) and validators.is_valid_point_string(value):
+            noparens = value.removeprefix("(").removesuffix(")")
+            latitude, longitude = noparens.split(',')
+            return (Decimal(latitude.strip()), Decimal(longitude.strip()))
         raise exceptions.ValidationError("This value must be a point-string.")
 
     def get_db_prep_value(self, value, connection, prepared=False):
diff --git a/python/nav/models/manage.py b/python/nav/models/manage.py
index 2d5c3492ce..896a2c2242 100644
--- a/python/nav/models/manage.py
+++ b/python/nav/models/manage.py
@@ -509,12 +509,9 @@ def get_short_sysname(self):
         """Returns sysname without the domain suffix if specified in the
         DOMAIN_SUFFIX setting in nav.conf"""
 
-        if settings.DOMAIN_SUFFIX is not None and self.sysname.endswith(
-            settings.DOMAIN_SUFFIX
-        ):
-            return self.sysname[: -len(settings.DOMAIN_SUFFIX)]
-        else:
-            return self.sysname or self.ip
+        if settings.DOMAIN_SUFFIX is not None:
+            return self.sysname.removesuffix(settings.DOMAIN_SUFFIX)
+        return self.sysname or self.ip
 
     def is_on_maintenance(self):
         """Returns True if this netbox is currently on maintenance"""
diff --git a/python/nav/models/profiles.py b/python/nav/models/profiles.py
index c5d97f0203..8fea91f85e 100644
--- a/python/nav/models/profiles.py
+++ b/python/nav/models/profiles.py
@@ -282,9 +282,9 @@ def locked(self):
 
     @locked.setter
     def locked(self, value):
-        if not value and self.password.startswith('!'):
-            self.password = self.password[1:]
-        elif value and not self.password.startswith('!'):
+        if not value:
+            self.password = self.password.removeprefix("!")
+        elif not self.password.startswith('!'):
             self.password = '!' + self.password
 
     @property
diff --git a/python/nav/startstop.py b/python/nav/startstop.py
index 16cfea6788..b8c3b808a4 100644
--- a/python/nav/startstop.py
+++ b/python/nav/startstop.py
@@ -43,7 +43,7 @@ def get_info_from_content(content):
         if not line.startswith('#'):
             break
         elif line.startswith(INFOHEAD):
-            return line[len(INFOHEAD) :].strip()
+            return line.removeprefix(INFOHEAD).strip()
 
 
 class Service(object):
diff --git a/python/nav/statemon/abstractchecker.py b/python/nav/statemon/abstractchecker.py
index dff8e6681b..f998087308 100644
--- a/python/nav/statemon/abstractchecker.py
+++ b/python/nav/statemon/abstractchecker.py
@@ -230,8 +230,7 @@ def get_type(cls):
         """Returns the name of the handler."""
         suffix = "checker"
         name = cls.__name__.lower()
-        if name.endswith(suffix):
-            name = name[: -len(suffix)]
+        name = name.removesuffix(suffix)
         return name
 
     def get_address(self):
diff --git a/python/nav/statemon/checker/FtpChecker.py b/python/nav/statemon/checker/FtpChecker.py
index dd8d50f494..d18c815ce5 100644
--- a/python/nav/statemon/checker/FtpChecker.py
+++ b/python/nav/statemon/checker/FtpChecker.py
@@ -51,7 +51,7 @@ def execute(self):
             version = ''
             for line in welcome.split('\n'):
                 if line.startswith('220 '):
-                    version = line[4:].strip()
+                    version = line.removeprefix('220 ').strip()
             self.version = version
 
             username = self.args.get('username', '')
diff --git a/python/nav/statemon/checker/MysqlChecker.py b/python/nav/statemon/checker/MysqlChecker.py
index 525ecdd781..64c0e9926b 100644
--- a/python/nav/statemon/checker/MysqlChecker.py
+++ b/python/nav/statemon/checker/MysqlChecker.py
@@ -92,7 +92,7 @@ def read_packet(self):
 
         data = self.file.read(size)
         if data.startswith(b'\xff'):
-            error = data[3:].decode("utf-8")
+            error = data.removeprefix(b'\xff').decode("utf-8")
             raise MysqlError(error)
 
         return data
diff --git a/python/nav/statemon/checkermap.py b/python/nav/statemon/checkermap.py
index dbe607c42a..5fec492a68 100644
--- a/python/nav/statemon/checkermap.py
+++ b/python/nav/statemon/checkermap.py
@@ -63,6 +63,6 @@ def parsedir():
     fnames = os.listdir(CHECKER_DIR)
     for fname in fnames:
         if fname.endswith(HANDLER_PATTERN):
-            key = fname[: -len(HANDLER_PATTERN)].lower()
+            key = fname.removesuffix(HANDLER_PATTERN).lower()
             handler = fname[:-3]
             register(key, handler)
diff --git a/python/nav/web/geomap/db.py b/python/nav/web/geomap/db.py
index 99889821d2..2651315620 100644
--- a/python/nav/web/geomap/db.py
+++ b/python/nav/web/geomap/db.py
@@ -367,9 +367,8 @@ def get_data(db_cursor, bounds, time_interval=None):
     for netbox in netboxes:
         netbox['load'] = float('nan')
         netbox['real_sysname'] = netbox['sysname']
-        if _domain_suffix and netbox['sysname'].endswith(_domain_suffix):
-            hostname_length = len(netbox['sysname']) - len(_domain_suffix)
-            netbox['sysname'] = netbox['sysname'][0:hostname_length]
+        if _domain_suffix:
+            netbox['sysname'] = netbox['sysname'].removesuffix(_domain_suffix)
 
     return netboxes, connections
 
diff --git a/tests/integration/models/model_test.py b/tests/integration/models/model_test.py
index e36e0a5a3f..2e356957f4 100644
--- a/tests/integration/models/model_test.py
+++ b/tests/integration/models/model_test.py
@@ -4,6 +4,7 @@
 Intended purpose is to catch obvious omissions in DB state or the Django models
 themselves.
 """
+
 import os
 
 from django.db import connection
@@ -21,7 +22,7 @@
 # Ensure that all modules are loaded
 for file_name in os.listdir(os.path.dirname(nav.models.__file__)):
     if file_name.endswith('.py') and not file_name.startswith('__init__'):
-        module_name = file_name.replace('.py', '')
+        module_name = file_name.removesuffix('.py')
         __import__('nav.models.%s' % module_name)