diff --git a/src/bindings/python/constraints.txt b/src/bindings/python/constraints.txt
index 1b8c6177a26459..9d36ab6617f204 100644
--- a/src/bindings/python/constraints.txt
+++ b/src/bindings/python/constraints.txt
@@ -21,5 +21,5 @@ docopt~=0.6.2
 paddlepaddle==2.5.2
 tensorflow>=1.15.5,<2.17.0
 six~=1.16.0
-protobuf>=3.18.1,<4.0.0
+protobuf>=5.27.2,<6.0.0
 onnx==1.15.0