diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
index d2c7b98adc..8f293ecb00 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
@@ -18,10 +18,7 @@
     TYPE_CHECKING,
     Any,
     Callable,
-    Iterable,
     MutableSequence,
-    Optional,
-    Union,
 )
 
 from opentelemetry._events import EventLogger
@@ -33,15 +30,19 @@
 from opentelemetry.trace import SpanKind, Tracer
 
 if TYPE_CHECKING:
+    from google.cloud.aiplatform_v1.services.prediction_service import client
     from google.cloud.aiplatform_v1.types import (
         content,
         prediction_service,
     )
-    from vertexai.generative_models import (
-        GenerationResponse,
+    from google.cloud.aiplatform_v1beta1.services.prediction_service import (
+        client as client_v1beta1,
     )
-    from vertexai.generative_models._generative_models import (
-        _GenerativeModel,
+    from google.cloud.aiplatform_v1beta1.types import (
+        content as content_v1beta1,
+    )
+    from google.cloud.aiplatform_v1beta1.types import (
+        prediction_service as prediction_service_v1beta1,
     )
 
 
@@ -49,12 +50,15 @@
 # https://github.com/googleapis/python-aiplatform/blob/v1.76.0/google/cloud/aiplatform_v1/services/prediction_service/client.py#L2088
 # to handle named vs positional args robustly
 def _extract_params(
-    request: Optional[
-        Union[prediction_service.GenerateContentRequest, dict[Any, Any]]
-    ] = None,
+    request: prediction_service.GenerateContentRequest
+    | prediction_service_v1beta1.GenerateContentRequest
+    | dict[Any, Any]
+    | None = None,
     *,
-    model: Optional[str] = None,
-    contents: Optional[MutableSequence[content.Content]] = None,
+    model: str | None = None,
+    contents: MutableSequence[content.Content]
+    | MutableSequence[content_v1beta1.Content]
+    | None = None,
     **_kwargs: Any,
 ) -> GenerateContentParams:
     # Request vs the named parameters are mututally exclusive or the RPC will fail
@@ -86,9 +90,12 @@ def generate_content_create(
 
     def traced_method(
         wrapped: Callable[
-            ..., GenerationResponse | Iterable[GenerationResponse]
+            ...,
+            prediction_service.GenerateContentResponse
+            | prediction_service_v1beta1.GenerateContentResponse,
         ],
-        instance: _GenerativeModel,
+        instance: client.PredictionServiceClient
+        | client_v1beta1.PredictionServiceClient,
         args: Any,
         kwargs: Any,
     ):
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
index c0bff12824..183a445f3d 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
@@ -20,7 +20,6 @@
 from typing import (
     TYPE_CHECKING,
     Mapping,
-    Optional,
     Sequence,
 )
 
@@ -31,18 +30,32 @@
 
 if TYPE_CHECKING:
     from google.cloud.aiplatform_v1.types import content, tool
+    from google.cloud.aiplatform_v1beta1.types import (
+        content as content_v1beta1,
+    )
+    from google.cloud.aiplatform_v1beta1.types import (
+        tool as tool_v1beta1,
+    )
 
 
 @dataclass(frozen=True)
 class GenerateContentParams:
     model: str
-    contents: Optional[Sequence[content.Content]] = None
-    system_instruction: Optional[content.Content | None] = None
-    tools: Optional[Sequence[tool.Tool]] = None
-    tool_config: Optional[tool.ToolConfig] = None
-    labels: Optional[Mapping[str, str]] = None
-    safety_settings: Optional[Sequence[content.SafetySetting]] = None
-    generation_config: Optional[content.GenerationConfig] = None
+    contents: (
+        Sequence[content.Content] | Sequence[content_v1beta1.Content] | None
+    ) = None
+    system_instruction: content.Content | content_v1beta1.Content | None = None
+    tools: Sequence[tool.Tool] | Sequence[tool_v1beta1.Tool] | None = None
+    tool_config: tool.ToolConfig | tool_v1beta1.ToolConfig | None = None
+    labels: Mapping[str, str] | None = None
+    safety_settings: (
+        Sequence[content.SafetySetting]
+        | Sequence[content_v1beta1.SafetySetting]
+        | None
+    ) = None
+    generation_config: (
+        content.GenerationConfig | content_v1beta1.GenerationConfig | None
+    ) = None
 
 
 def get_genai_request_attributes(