diff --git a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_cdrom_device.cfg b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_cdrom_device.cfg
index 0b820f8dad..0ea5c8705c 100644
--- a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_cdrom_device.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_cdrom_device.cfg
@@ -7,6 +7,7 @@
         - without_cdrom:
             only os_dev
         - with_cdrom_with_no_src:
+            no s390-virtio
             cdrom1_attrs = {'target': {'dev': 'sda', 'bus': 'sata'}, **${cdrom_attrs}}
             aarch64:
                 cdrom1_attrs = {'target': {'dev': 'sda', 'bus': 'scsi'}, **${cdrom_attrs}}
@@ -14,19 +15,20 @@
         - with_cdrom:
             check_bootable_iso = "yes"
             cdrom1_attrs = {'source': {'attrs': {'file': boot_img_path}}, 'target': {'dev': 'sda', 'bus': 'scsi'}, **${cdrom_attrs}}
-            bootable_patterns = ["begin the installation process|Install Red Hat Enterprise"]
+            bootable_patterns = ["begin the installation process|Install Red Hat Enterprise|Starting installer"]
         - multi_cdroms:
             cdrom1_attrs = {'target': {'dev': 'sda', 'bus': 'scsi'}, **${cdrom_attrs}}
             cdrom2_attrs = {'source': {'attrs': {'file': boot_img_path}}, 'target': {'dev': 'sdb', 'bus': 'sata'}, **${cdrom_attrs}}
-            aarch64:
+            aarch64, s390-virtio:
                 cdrom2_attrs = {'source': {'attrs': {'file': boot_img_path}}, 'target': {'dev': 'sdb', 'bus': 'scsi'}, **${cdrom_attrs}}
             cdrom_boot_order:
                 check_bootable_iso = "yes"
-                bootable_patterns = ["begin the installation process|Install Red Hat Enterprise"]
+                bootable_patterns = ["begin the installation process|Install Red Hat Enterprise|Starting installer"]
             os_dev:
                status_error = "yes"  
     variants:
         - os_dev:
+          no s390-virtio
             os_attrs_boots = ['cdrom']
         - cdrom_boot_order:
     variants firmware_type:
@@ -36,3 +38,4 @@
                 status_error = "yes"
         - ovmf:
             only q35, aarch64
+        - default:
diff --git a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_disk_device.cfg b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_disk_device.cfg
index 0f913912b4..97b9b4f158 100644
--- a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_disk_device.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_from_disk_device.cfg
@@ -4,6 +4,7 @@
     disk1_attrs_target = {'dev': 'vda', 'bus': 'virtio'}
     variants:
         - os_dev:
+            no s390-virtio
             os_attrs_boots = ['hd']
             disk1_attrs = {'target': ${disk1_attrs_target}}
             variants:
@@ -24,8 +25,13 @@
                     disk2_attrs = {'target': {'dev': 'sda', 'bus': 'scsi'}}
                     seabios:
                         status_error = "yes"
+                - multi_disks_bootable:
+                    disk1_img = "copied_original.qcow2"
+                    disk1_attrs = {'target': ${disk1_attrs_target}}
+                    disk2_attrs = {'target': {'dev': 'sda', 'bus': 'scsi'}}
     variants firmware_type:
         - seabios:
             only x86_64
         - ovmf:
             only q35, aarch64
+        - default:
diff --git a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_dev.cfg b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_dev.cfg
index ad60e5d8c9..32a76da370 100644
--- a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_dev.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_dev.cfg
@@ -8,6 +8,7 @@
       os_dict = {'boots': ['%s', '%s'], 'bootmenu_enable': 'yes'}
     cdrom_dict = {'source': {'attrs': {'file': '%s'}}, 'type_name': 'file', 'device': 'cdrom', 'driver': {'name': 'qemu', 'type': 'raw'}, 'target': {'dev': 'sda', 'bus': '${target_bus}'}}
     check_prompt = ["begin the installation process|Install Red Hat Enterprise"]
+    no s390-virtio
     variants first_dev:
         - hd:
             variants second_dev:
diff --git a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_order.cfg b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_order.cfg
index 8821b5f6f6..e1f3c2e69c 100644
--- a/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_order.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/boot_order/boot_with_multiple_boot_order.cfg
@@ -6,8 +6,11 @@
     aarch64:
       os_dict = {'bootmenu_enable': 'yes'}
       target_bus = 'scsi'
+    s390-virtio:
+      os_dict = {'bootmenu_enable': 'no'}
+      target_bus = 'scsi'
     cdrom_dict = {'source': {'attrs': {'file': '%s'}}, 'type_name': 'file', 'device': 'cdrom', 'driver': {'name': 'qemu', 'type': 'raw'}, 'target': {'dev': 'sda', 'bus': '${target_bus}'}}
-    check_prompt = ["begin the installation process|Install Red Hat Enterprise"]
+    check_prompt = ["begin the installation process|Install Red Hat Enterprise|Starting installer"]
     variants first_dev:
         - hd:
             disk_order = {'boot': '1'}
@@ -16,13 +19,20 @@
                     cdrom_order = {'boot': '2'}
                     variants bootable_device:
                         - hd_bootable:
+                            variants:
+                                - @default:
+                                - with_loadparm:
+                                    only s390-virtio
+                                    disk_order = {'boot': '1', 'loadparm': '1'}
+                                    test_cmd = "lsreipl"
+                                    expected_output = Loadparm:\s+"1"
                         - cdrom_bootable:
                 - network:
                     network_order = {'boot': '2'}
                     variants bootable_device:
                         - hd_bootable:
                         - network_bootable:
-                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4"]
+                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4|Trying pxelinux.cfg files"]
         - cdrom:
             cdrom_order = {'boot': '1'}
             variants second_dev:
@@ -30,13 +40,20 @@
                     disk_order = {'boot': '2'}
                     variants bootable_device:
                         - hd_bootable:
+                            variants:
+                                - @default:
+                                - with_loadparm:
+                                    only s390-virtio
+                                    disk_order = {'boot': '2', 'loadparm': '2'}
+                                    test_cmd = "lsreipl"
+                                    expected_output = Loadparm:\s+"2"
                         - cdrom_bootable:
                 - network:
                     network_order = {'boot': '2'}
                     variants bootable_device:
                         - cdrom_bootable:
                         - network_bootable:
-                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4"]
+                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4|Trying pxelinux.cfg files"]
         - network:
             network_order = {'boot': '1'}
             variants second_dev:
@@ -44,11 +61,18 @@
                     disk_order = {'boot': '2'}
                     variants bootable_device:
                         - hd_bootable:
+                            variants:
+                                - @default:
+                                - with_loadparm:
+                                    only s390-virtio
+                                    disk_order = {'boot': '2', 'loadparm': '2'}
+                                    test_cmd = "lsreipl"
+                                    expected_output = Loadparm:\s+"2"
                         - network_bootable:
-                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4"]
+                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4|Trying pxelinux.cfg files"]
                 - cdrom:
                     cdrom_order = {'boot': '2'}
                     variants bootable_device:
                         - cdrom_bootable:
                         - network_bootable:
-                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4"]
+                            check_prompt = ["iPXE initialising devices|Start PXE over IPv4|Trying pxelinux.cfg files"]
diff --git a/libvirt/tests/cfg/guest_os_booting/boot_order/hotplug_device_with_boot_order.cfg b/libvirt/tests/cfg/guest_os_booting/boot_order/hotplug_device_with_boot_order.cfg
index 2722ca402f..9dfa260751 100644
--- a/libvirt/tests/cfg/guest_os_booting/boot_order/hotplug_device_with_boot_order.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/boot_order/hotplug_device_with_boot_order.cfg
@@ -13,6 +13,8 @@
             bus_type = "usb"
             target_disk = "sda"
             device_dict = {"type_name":"file", "target":{"dev": "${target_disk}", "bus": "${bus_type}"}, 'boot': '2'}
+            s390-virtio:
+                expected_error = unsupported configuration: This QEMU doesn't support
         - filesystem_device:
             target_dir = "mount_tag"
             source_dir = "/tmp"
diff --git a/libvirt/tests/cfg/guest_os_booting/direct_kernel_boot/direct_kernel_boot.cfg b/libvirt/tests/cfg/guest_os_booting/direct_kernel_boot/direct_kernel_boot.cfg
index 563c252244..4d4a51340c 100644
--- a/libvirt/tests/cfg/guest_os_booting/direct_kernel_boot/direct_kernel_boot.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/direct_kernel_boot/direct_kernel_boot.cfg
@@ -6,6 +6,8 @@
     initrd_url = "${repo_url}/images/pxeboot/initrd.img"
     vmlinuz_url = "${repo_url}/images/pxeboot/vmlinuz"
     direct_kernel_dict = {'cmdline': 'console=ttyS0 inst.repo=${repo_url}', 'initrd': '%s', 'kernel': '%s'}
+    s390-virtio:
+        direct_kernel_dict = {'cmdline': 'console=ttysclp0 inst.repo=${repo_url}', 'initrd': '%s', 'kernel': '%s'}
     variants:
         - start_guest:
             check_prompt = "Starting installer"
diff --git a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/os_acpi.cfg b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/os_acpi.cfg
index 20d6384228..8cf656f467 100644
--- a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/os_acpi.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/os_acpi.cfg
@@ -4,7 +4,7 @@
     acpi_url = "EXAMPLE_ACPI_URL"
     acpi_file = "slic.dat"
     acpi_dict = {'acpi': {'table_type': 'slic', 'table': '%s'}}
-    no aarch64
+    no aarch64, s390-virtio
     variants:
         - start_guest:
             cmd_in_guest = "acpidump"
diff --git a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/smbios_mode.cfg b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/smbios_mode.cfg
index 88eda2e886..e0a034ed82 100644
--- a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/smbios_mode.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/smbios_mode.cfg
@@ -1,6 +1,7 @@
 - guest_os_booting.smbios_mode:
     type = smbios_mode
     start_vm = no
+    no s390-virtio
     variants:
         - positive_test:
             variants smbios_mode:
diff --git a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/sysinfo_fwcfg.cfg b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/sysinfo_fwcfg.cfg
index a9d57e5fe1..32970c35e2 100644
--- a/libvirt/tests/cfg/guest_os_booting/firmware_configuration/sysinfo_fwcfg.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/firmware_configuration/sysinfo_fwcfg.cfg
@@ -2,6 +2,7 @@
     type = sysinfo_fwcfg
     start_vm = no
     entry_value = "example value"
+    no s390-virtio
     variants:
         - positive_test:
             variants:
diff --git a/libvirt/tests/cfg/guest_os_booting/migration/migration_boot.cfg b/libvirt/tests/cfg/guest_os_booting/migration/migration_boot.cfg
index 58e0e2895f..7fd79d42f7 100644
--- a/libvirt/tests/cfg/guest_os_booting/migration/migration_boot.cfg
+++ b/libvirt/tests/cfg/guest_os_booting/migration/migration_boot.cfg
@@ -25,6 +25,7 @@
     virsh_migrate_connect_uri = "qemu:///system"
     variants:
         - os_dev:
+            no s390-virtio
             os_attrs_boots = ['hd', 'cdrom', 'network']
         - boot_order:
             disk_boot_idx = 1
diff --git a/libvirt/tests/src/guest_os_booting/boot_order/boot_from_cdrom_device.py b/libvirt/tests/src/guest_os_booting/boot_order/boot_from_cdrom_device.py
index d9f7572f3b..4473f5ac1c 100644
--- a/libvirt/tests/src/guest_os_booting/boot_order/boot_from_cdrom_device.py
+++ b/libvirt/tests/src/guest_os_booting/boot_order/boot_from_cdrom_device.py
@@ -56,9 +56,7 @@ def update_vm_xml(vm, params, cdrom_attrs_list):
         os_attrs = {'boots': os_attrs_boots}
         vmxml.setup_attrs(os=os_attrs)
     else:
-        vm_os = vmxml.os
-        vm_os.del_boots()
-        vmxml.os = vm_os
+        vmxml.remove_all_boots()
     if "yes" == params.get("check_bootable_iso", "no"):
         os_attrs.update({'bootmenu_enable': 'yes',
                          'bootmenu_timeout': '3000'})
diff --git a/libvirt/tests/src/guest_os_booting/boot_order/boot_from_disk_device.py b/libvirt/tests/src/guest_os_booting/boot_order/boot_from_disk_device.py
index d6fecf2f7a..7ef8e19ddd 100644
--- a/libvirt/tests/src/guest_os_booting/boot_order/boot_from_disk_device.py
+++ b/libvirt/tests/src/guest_os_booting/boot_order/boot_from_disk_device.py
@@ -6,17 +6,19 @@
 
 from virttest.libvirt_xml import vm_xml
 from virttest.libvirt_xml.devices import disk
+from virttest.utils_misc import cmd_status_output
 from virttest.utils_libvirt import libvirt_disk
 from virttest.utils_libvirt import libvirt_vmxml
 
 from provider.guest_os_booting import guest_os_booting_base
 
 
-def parse_disks_attrs(vmxml, params):
+def parse_disks_attrs(vmxml, test, params):
     """
     Parse disk devices' attrs
 
     :param vmxml: The vmxml object
+    :param test: The test object
     :param params: Dictionary with the test parameters
     :return: (Newly created disk image path, list of disk devices' attrs)
     """
@@ -28,7 +30,14 @@ def parse_disks_attrs(vmxml, params):
     if disk1_img:
         disk1_img_path = os.path.join(data_dir.get_data_dir(), 'images',
                                       disk1_img)
-        libvirt_disk.create_disk('file', disk1_img_path, disk_format='qcow2')
+        if disk1_img == "copied_original.qcow2":
+            org_source_file = disk_org_attrs['source']['attrs']['file']
+            cmd_status_output("qemu-img convert "
+                              "-f qcow2 -O qcow2 -o lazy_refcounts=on "
+                              f"{org_source_file} {disk1_img_path}")
+        else:
+            libvirt_disk.create_disk('file', disk1_img_path, disk_format='qcow2')
+
         disk1_attrs = copy.deepcopy(disk_org_attrs)
         disk1_attrs['source'] = {'attrs': {'file': disk1_img_path}}
         disk_attrs_list.append(disk1_attrs)
@@ -84,15 +93,19 @@ def run(test, params, env):
     vm = env.get_vm(vm_name)
     vmxml = vm_xml.VMXML.new_from_inactive_dumpxml(vm.name)
     bkxml = vmxml.copy()
+    session = None
 
     try:
-        disk1_img_path, disk_attrs_list = parse_disks_attrs(vmxml, params)
+        disk1_img_path, disk_attrs_list = parse_disks_attrs(vmxml, test, params)
         update_vm_xml(vm, params, disk_attrs_list)
         test.log.debug(vm_xml.VMXML.new_from_dumpxml(vm.name))
 
         vm.start()
         try:
-            vm.wait_for_serial_login().close()
+            #vm.wait_for_serial_login(timeout=120).close()
+            session = vm.wait_for_serial_login()
+            if 'emergency mode' in session.get_output():
+                test.fail("Couldn't boot correctly")
         except remote.LoginTimeoutError as detail:
             if status_error:
                 test.log.debug("Found the expected error: %s", detail)
@@ -100,6 +113,8 @@ def run(test, params, env):
                 test.fail(detail)
 
     finally:
+        if session:
+            session.close()
         bkxml.sync()
         if disk1_img_path and os.path.isfile(disk1_img_path):
             test.log.debug(f"removing {disk1_img_path}")
diff --git a/libvirt/tests/src/guest_os_booting/boot_order/boot_with_multiple_boot_order.py b/libvirt/tests/src/guest_os_booting/boot_order/boot_with_multiple_boot_order.py
index b3469f6bdd..ac9f35fa02 100644
--- a/libvirt/tests/src/guest_os_booting/boot_order/boot_with_multiple_boot_order.py
+++ b/libvirt/tests/src/guest_os_booting/boot_order/boot_with_multiple_boot_order.py
@@ -3,6 +3,7 @@
 #   Author: Meina Li <meili@redhat.com>
 
 import os
+import re
 
 from avocado.utils import process
 
@@ -74,10 +75,13 @@ def run(test, params, env):
     check_prompt = eval(params.get("check_prompt", "[]"))
     bootable_device = params.get("bootable_device")
     os_dict = eval(params.get("os_dict"))
+    test_cmd = params.get("test_cmd", None)
+    expected_output = params.get("expected_output", None)
 
     vm = env.get_vm(vm_name)
     vmxml = vm_xml.VMXML.new_from_inactive_dumpxml(vm.name)
     bkxml = vmxml.copy()
+    session = None
 
     try:
         test.log.info("TEST_SETUP: prepare a guest with necessary attributes.")
@@ -89,12 +93,20 @@ def run(test, params, env):
         test.log.debug(f"The current guest xml is: {vmxml}")
         test.log.info("TEST_STEP2: check the guest boot from expected device.")
         if bootable_device == "hd_bootable":
-            vm.wait_for_login(timeout=360).close()
+            session = vm.wait_for_login(timeout=360)
             test.log.debug("Succeed to boot %s", vm_name)
+            if test_cmd is not None:
+                output = session.cmd(test_cmd)
+                if not re.search(expected_output, output):
+                    test.fail(f"Couldn't get {expected_output}, got instead {output}")
+                test.log.debug("Succeed to set %s", expected_output)
+            session.close()
         else:
             vm.serial_console.read_until_output_matches(check_prompt, timeout=300,
                                                         internal_timeout=0.5)
     finally:
+        if session:
+            session.close()
         bkxml.sync()
         for file in file_list:
             if os.path.exists(file):
diff --git a/libvirt/tests/src/guest_os_booting/direct_kernel_boot/direct_kernel_boot.py b/libvirt/tests/src/guest_os_booting/direct_kernel_boot/direct_kernel_boot.py
index 90124677cd..77a70401e6 100644
--- a/libvirt/tests/src/guest_os_booting/direct_kernel_boot/direct_kernel_boot.py
+++ b/libvirt/tests/src/guest_os_booting/direct_kernel_boot/direct_kernel_boot.py
@@ -35,8 +35,8 @@ def run(test, params, env):
     bkxml = vmxml.copy()
 
     try:
-        boot_initrd = os.path.join(data_dir.get_data_dir(), "initrd.img")
-        boot_vmlinuz = os.path.join(data_dir.get_data_dir(), "vmlinuz")
+        boot_initrd = os.path.join(data_dir.get_data_dir(), initrd_url.split("/")[-1])
+        boot_vmlinuz = os.path.join(data_dir.get_data_dir(), vmlinuz_url.split("/")[-1])
         url_download(initrd_url, boot_initrd)
         url_download(vmlinuz_url, boot_vmlinuz)
         direct_kernel_dict = eval(params.get("direct_kernel_dict")
diff --git a/provider/guest_os_booting/guest_os_booting_base.py b/provider/guest_os_booting/guest_os_booting_base.py
index 90c64d6217..9e637c2727 100644
--- a/provider/guest_os_booting/guest_os_booting_base.py
+++ b/provider/guest_os_booting/guest_os_booting_base.py
@@ -1,4 +1,5 @@
 import logging
+import platform
 
 from avocado.core import exceptions
 from avocado.utils import distro
@@ -25,6 +26,9 @@ def get_vm(params):
     firmware_type = params.get('firmware_type')
     detected_distro = distro.detect()
     os_type_dict = {}
+    if platform.machine() == "s390x":
+        return vms[0]
+
     for _vm in vms:
         if os_type_dict.get("seabios") and os_type_dict.get("ovmf"):
             break