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TUTORIAL.md

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Tutorial

To test if you have installed HLA-MA correctly, you can run it on the provided test data.

If you did not already, activate the conda environment

# source activate hlama

and download HLA-MA from github for the test data.

# git clone https://github.com/bihealth/hlama.git

Then, call HLA-MA:

# cd hlama
# hlama --tumor-normal tests/data/tumor_normal/donors.tsv  --work-dir TEST --reads-base-dir tests/data/tumor_normal --num-threads 4

Afterwards, you should find the following files and directories in TEST:

data.json
donor1_normal.d
donor1_tumor.d
donor1_tumor_rna.d
donor2_normal.d
donor2_tumor.d
report.txt
Snakefile
tmp

with the HLA-MA results in report.txt and all optitype results in the directories suffixed with .d.

# cat report.txt 
donor2_tumor    OK      OK
donor1_tumor    OK      OK
donor1_tumor_rna        OK      1