diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index b600a8e8..8536f577 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -16,12 +16,20 @@ jobs:
       fail-fast: false
       matrix:
         os: [macos-latest, windows-latest, ubuntu-latest]
-        python: [3.7, 3.8]
+        tox_env: [py37, py38]
         include:
-          - python: 3.7
-            tox_env: py37
-          - python: 3.8
-            tox_env: py38
+          - tox_env: py37
+            python: 3.7
+          - tox_env: py38
+            python: 3.8
+            
+          # add additional jobs for future compatibility test
+          - tox_env: py38-orange-develop
+            python: 3.8
+            os: ubuntu-latest
+          - tox_env: py38-bioinformatics-develop
+            python: 3.8
+            os: ubuntu-latest
 
     steps:
       - uses: actions/checkout@v2
diff --git a/tox.ini b/tox.ini
index bb810749..8f6d9d06 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,9 +1,9 @@
 [tox]
 envlist =
-    py{37,38}
+    py{37,38,39}-{orange,bioinformatics}-develop
 skip_missing_interpreters = true
 isolated_build = true
-minversion = 3.7.0
+minversion = 3.6.0
 
 [testenv]
 extras = test
@@ -22,8 +22,9 @@ setenv =
 deps =
     pyqt5
     pyqtwebengine
+    orange-develop: git+git://github.com/biolab/orange3.git#egg=orange3
+    bioinformatics-develop: git+git://github.com/biolab/orange3-bioinformatics.git#egg=orange3-bioinformatics
 commands_pre =
-    pip --version
     # Verify installed packages have compatible dependencies
     pip check
     # freeze environment