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suggestion on filtering genes of interest #24

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Rohit-Satyam opened this issue Nov 1, 2023 · 2 comments
Open

suggestion on filtering genes of interest #24

Rohit-Satyam opened this issue Nov 1, 2023 · 2 comments

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@Rohit-Satyam
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Hi @dosorio

I want to ask if you have any recommended way of filtering the DEGs that we get out of scTenifoldKnK. I observed that there are genes which have more than 10 fold perturbation such as the following genes:

gene	distance	Z	FC	p.value	p.adj
PF3D7-0617800	1.73822398699258E-06	6.06037047499314	2917.01596234589	0	0	late trophs
PF3D7-0402000	1.63063171540528E-06	4.28111337895561	2032.22476480867	0	0	early trophs

Besides, do you have any recommendations to shortlist genes of interest based on Z-scores as well?
@Rohit-Satyam
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hi @dosorio @yanzhong07 Any input would be valuable. Please respond.

@Rohit-Satyam
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@dosorio @yanzhong07 Can you please drop some insights?

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