diff --git a/data/aml_morita/trees_aml_morita.json b/data/aml_morita/trees_aml_morita.json
index 7ad6166..7852a53 100644
--- a/data/aml_morita/trees_aml_morita.json
+++ b/data/aml_morita/trees_aml_morita.json
@@ -1 +1 @@
-data_aml_morita={"trees": {"AML-119-001": {"tree": {"node_id": "3", "label": ["Root"], "variant": "", "name": "3", "matching_label": 4, "children": [{"node_id": "2", "size_percent": 0.097, "matching_label": 3, "gene_events": {"SF3B1": {"SNV": "p.K666N"}}, "children": [{"node_id": "0", "size_percent": 0.407, "matching_label": 1, "gene_events": {"IDH1": {"SNV": "p.R132H"}}, "children": [{"node_id": "1", "size_percent": 0.497, "matching_label": 2, "gene_events": {"NPM1": {"SNV": "p.L287fs"}}}]}]}]}, "metadata": {"VitalStatus": "Alive NOS"}}, "AML-24-001": {"tree": {"node_id": "5", "label": ["Root"], "variant": "", "name": "5", "matching_label": 4, "children": [{"node_id": "0", "size_percent": 0.038, "matching_label": 5, "gene_events": {"DNMT3A": {"SNV": "p.R882H"}}, "children": [{"node_id": "3", "size_percent": 0.301, "matching_label": 8, "gene_events": {"U2AF1": {"SNV": "p.S34Y"}}, "children": [{"node_id": "1", "size_percent": 0.305, "matching_label": 6, "gene_events": {"FLT3-ITD": {"SNV": ""}}, "children": [{"node_id": "4", "size_percent": 0.339, "matching_label": 9, "gene_events": {"WT1": {"SNV": "p.C453Y"}}}]}, {"node_id": "2", "size_percent": 0.018, "matching_label": 7, "gene_events": {"FLT3": {"SNV": "p.A680V"}}}]}]}]}, "metadata": {"VitalStatus": "Dead NOS"}}, "AML-113-001": {"tree": {"node_id": "4", "label": ["Root"], "variant": "", "name": "4", "matching_label": 4, "children": [{"node_id": "2", "size_percent": 0.342, "matching_label": 2, "gene_events": {"NPM1": {"SNV": "p.L287fs"}}}, {"node_id": "3", "size_percent": 0.097, "matching_label": 10, "gene_events": {"STAG2": {"SNV": "p.P1040fs"}}, "children": [{"node_id": "0", "size_percent": 0.475, "matching_label": 5, "gene_events": {"DNMT3A": {"SNV": "p.G298R"}}, "children": [{"node_id": "1", "size_percent": 0.086, "matching_label": 1, "gene_events": {"IDH1": {"SNV": "p.R132H"}}}]}]}]}, "metadata": {"VitalStatus": "Alive NOS"}}, "AML-110-001": {"tree": {"node_id": "2", "label": ["Root"], "variant": "", "name": "2", "matching_label": 4, "children": [{"node_id": "1", "size_percent": 0.878, "matching_label": 12, "gene_events": {"TP53": {"SNV": "p.C176Y"}}, "children": [{"node_id": "0", "size_percent": 0.122, "matching_label": 11, "gene_events": {"KRAS": {"SNV": "p.G12V"}}}]}]}, "metadata": {"VitalStatus": "Dead NOS"}}, "AML-83-002": {"tree": {"node_id": "5", "label": ["Root"], "variant": "", "name": "5", "matching_label": 4, "children": [{"node_id": "1", "size_percent": 0.033, "matching_label": 5, "gene_events": {"DNMT3A": {"SNV": "p.V763fs"}}, "children": [{"node_id": "2", "size_percent": 0.071, "matching_label": 13, "gene_events": {"IDH2": {"SNV": "p.R172K"}}, "children": [{"node_id": "0", "size_percent": 0.503, "matching_label": 5, "gene_events": {"DNMT3A": {"SNV": "p.L889P"}}, "children": [{"node_id": "3", "size_percent": 0.263, "matching_label": 14, "gene_events": {"NRAS": {"SNV": "p.G12A"}}}, {"node_id": "4", "size_percent": 0.129, "matching_label": 14, "gene_events": {"NRAS": 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"gene_events": {"DNMT3A": {"SNV": "p.R882H"}}, "children": [{"node_id": "3", "size_percent": 0.35, "matching_label": 15, "gene_events": {"SRSF2": {"SNV": "p.P95R"}}, "children": [{"node_id": "2", "size_percent": 0.2, "matching_label": 2, "gene_events": {"NPM1": {"SNV": "p.L287fs"}}}]}]}]}]}, "metadata": {"VitalStatus": "Alive NOS"}}, "AML-116-001": {"tree": {"node_id": "3", "label": ["Root"], "variant": "", "name": "3", "matching_label": 4, "children": [{"node_id": "2", "size_percent": 0.173, "matching_label": 16, "gene_events": {"TET2": {"SNV": "p.R1237X"}}, "children": [{"node_id": "1", "size_percent": 0.287, "matching_label": 16, "gene_events": {"TET2": {"SNV": "p.L1046fs"}}, "children": [{"node_id": "0", "size_percent": 0.487, "matching_label": 2, "gene_events": {"NPM1": {"SNV": "p.L287fs"}}}]}]}]}, "metadata": {"VitalStatus": "Alive NOS"}}, "AML-43-001": {"tree": {"node_id": "3", "label": ["Root"], "variant": "", "name": "3", "matching_label": 4, "children": [{"node_id": "2", 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"matching_label": 4, "children": [{"node_id": "0", "size_percent": 0.06, "matching_label": 6, "gene_events": {"FLT3-ITD": {"SNV": ""}}, "children": [{"node_id": "1", "size_percent": 0.105, "matching_label": 18, "gene_events": {"MYC": {"SNV": "p.P74Q"}}, "children": [{"node_id": "3", "size_percent": 0.308, "matching_label": 9, "gene_events": {"WT1": {"SNV": "p.R462W"}}}]}]}, {"node_id": "2", "size_percent": 0.527, "matching_label": 9, "gene_events": {"WT1": {"SNV": "p.A382fs"}}}]}, "metadata": {"VitalStatus": "Dead NOS"}}, "AML-74-001": {"tree": {"node_id": "5", "label": ["Root"], "variant": "", "name": "5", "matching_label": 4, "children": [{"node_id": "1", "size_percent": 0.249, "matching_label": 2, "gene_events": {"NPM1": {"SNV": "p.L287fs"}}, "children": [{"node_id": "0", "size_percent": 0.168, "matching_label": 11, "gene_events": {"KRAS": {"SNV": "p.G60D"}}}, {"node_id": "2", "size_percent": 0.188, "matching_label": 14, "gene_events": {"NRAS": {"SNV": "p.G12D"}}}, {"node_id": "3", 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diff --git a/data/brca_razavi/trees_brca_razavi.json b/data/brca_razavi/trees_brca_razavi.json
index d58df6b..1312193 100644
--- a/data/brca_razavi/trees_brca_razavi.json
+++ b/data/brca_razavi/trees_brca_razavi.json
@@ -1 +1 @@
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diff --git a/data/noble2022/trees_noble2022.json b/data/noble2022/trees_noble2022.json
index f18173b..bea5e2e 100644
--- a/data/noble2022/trees_noble2022.json
+++ b/data/noble2022/trees_noble2022.json
@@ -1 +1 @@
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diff --git a/data/tracerx/tracerx_lung/trees_tracerx_lung.json b/data/tracerx/tracerx_lung/trees_tracerx_lung.json
index 4f2393c..72d22f2 100644
--- a/data/tracerx/tracerx_lung/trees_tracerx_lung.json
+++ b/data/tracerx/tracerx_lung/trees_tracerx_lung.json
@@ -1 +1 @@
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0.6166845309524542}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0006_3", "distance": 0.5997326647709519}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0007_1", "distance": 0.6479178706534904}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_3", "distance": 0.6917518276312559}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0008_1", "distance": 0.7035877712426256}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0009_1", "distance": 0.6850398514996279}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0010_1", "distance": 0.6295387249913322}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0011_1", "distance": 0.5656864858048809}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0012_1", "distance": 0.6207969638598534}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0013_1", "distance": 0.6585040017489645}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0013_2", "distance": 0.6762426982694032}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0013_3", "distance": 0.6529407404003793}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0013_4", "distance": 0.655611434625768}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0014_1", "distance": 0.696747205451}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_4", "distance": 0.6856425684697431}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0015_1", "distance": 0.6718871882702249}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_1", "distance": 0.621758672255499}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_2", "distance": 0.6511392128252265}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_3", "distance": 0.6844731548599491}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_4", "distance": 0.7631171594124752}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_5", "distance": 0.6811014912668331}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_6", "distance": 0.8012439122066326}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_7", "distance": 0.764704403289327}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_8", "distance": 0.6912809536742985}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_9", "distance": 0.6976060119669405}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_5", "distance": 0.7184296803831816}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_10", "distance": 0.659577684651636}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_11", "distance": 0.709927966122618}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_12", "distance": 0.6261144740330469}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_13", "distance": 0.7350484091160988}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0016_14", "distance": 0.7141961695579355}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0017_1", "distance": 0.6173324658878244}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0018_1", "distance": 0.678621685485406}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0019_1", "distance": 0.6260067520323704}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0020_1", "distance": 0.7103367560920436}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0020_2", "distance": 0.7359636204716857}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_6", "distance": 0.6230549239982106}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0021_1", "distance": 0.6195334395259599}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0022_1", "distance": 0.6649358924941765}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0023_1", "distance": 0.6799923203577021}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0023_2", "distance": 0.6926368981478872}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0024_1", "distance": 0.6345626132268158}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0024_2", "distance": 0.6317640013838811}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0025_1", "distance": 0.6428318471207617}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0026_1", "distance": 0.7749880022552129}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0027_1", "distance": 0.6329564721609136}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0028_1", "distance": 0.7236065810083234}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_7", "distance": 0.6269489434332534}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0029_1", "distance": 0.6328775088923209}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0030_1", "distance": 0.7069556340673706}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0031_1", "distance": 0.6810650903984576}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0032_1", "distance": 0.6977941940768071}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0033_1", "distance": 0.5634430817626528}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0034_1", "distance": 0.6513057041339506}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0035_1", "distance": 0.6253972343737968}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0036_1", "distance": 0.6490521311864794}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0037_1", "distance": 0.6825330388895889}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0038_1", "distance": 0.5954052304839472}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_8", "distance": 0.7044550646091781}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0039_1", "distance": 0.5795223870110675}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0040_1", "distance": 0.7085536184540122}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0041_1", "distance": 0.6274829248386765}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0042_1", "distance": 0.5731052050186296}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0043_1", "distance": 0.5709895339831511}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0044_1", "distance": 0.5669454198520262}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0045_1", "distance": 0.6950168613455668}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0046_1", "distance": 0.6109920477185657}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0047_1", "distance": 0.7218480498422006}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0048_1", "distance": 0.6235600522069029}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_9", "distance": 0.667190867435526}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0049_1", "distance": 0.630070215332768}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0050_1", "distance": 0.6742434457987392}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0051_1", "distance": 0.4135692556270575}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0052_1", "distance": 0.6244326038425732}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0054_1", "distance": 0.6221489078691438}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0055_1", "distance": 0.7486883785074642}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0056_1", "distance": 0.6865851675317027}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0057_1", "distance": 0.6199864707719633}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0058_1", "distance": 0.654238390111411}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0059_1", "distance": 0.5640053447009938}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0001_10", "distance": 0.7111872161134019}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0060_1", "distance": 0.6695180394244445}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0061_1", "distance": 0.6553842601194468}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0062_1", "distance": 0.6253375843061153}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0062_2", "distance": 0.6193342726485085}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_1", "distance": 0.19658261063591842}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_2", "distance": 0.2653409174350533}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_3", "distance": 0.1509132162475132}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_4", "distance": 0.31749088534746783}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_5", "distance": 0.16635722057425573}, {"sample_1": "CRUK0063_6", "sample_2": "CRUK0063_6", "distance": 0.0}], "clusters": [["CRUK0001_7", "CRUK0001_6", "CRUK0001_2", "CRUK0001_10", "CRUK0001_5", "CRUK0001_9", "CRUK0001_11", "CRUK0001_8", "CRUK0001_1", "CRUK0001_3", "CRUK0001_4"], ["CRUK0011_1", "CRUK0038_1", "CRUK0042_1", "CRUK0044_1", "CRUK0059_1", "CRUK0069_1", "CRUK0017_1"], ["CRUK0054_1", "CRUK0012_1", "CRUK0019_1"], ["CRUK0013_1", "CRUK0013_2", "CRUK0061_1", "CRUK0013_3", "CRUK0013_4"], ["CRUK0016_7", "CRUK0016_4", "CRUK0016_6", "CRUK0016_14", "CRUK0016_11", "CRUK0016_13", "CRUK0016_10", "CRUK0016_12", "CRUK0016_8", "CRUK0016_9", "CRUK0016_2", "CRUK0016_5", "CRUK0016_1", "CRUK0016_3"], ["CRUK0051_1", "CRUK0063_1", "CRUK0063_4", "CRUK0063_2", "CRUK0063_5", "CRUK0063_3", "CRUK0063_6"], ["CRUK0097_1", "CRUK0098_1", "CRUK0074_1", "CRUK0071_1", "CRUK0052_1"], ["CRUK0014_1", "CRUK0027_1"], ["CRUK0073_1", "CRUK0062_1", "CRUK0062_2"], ["CRUK0022_1", "CRUK0004_1", "CRUK0058_1"], ["CRUK0070_1", "CRUK0067_1", "CRUK0075_1"], ["CRUK0031_1", "CRUK0002_1", "CRUK0002_2"], ["CRUK0034_1"], ["CRUK0068_1"], ["CRUK0009_1"], ["CRUK0087_1"], ["CRUK0085_1"], ["CRUK0036_1"], ["CRUK0081_1"], ["CRUK0055_1"], ["CRUK0065_1"], ["CRUK0005_1"], ["CRUK0078_1"], ["CRUK0099_1"], ["CRUK0035_1"], ["CRUK0032_1"], ["CRUK0082_1"], ["CRUK0010_1"], ["CRUK0093_1"], ["CRUK0095_1"], ["CRUK0077_1"], ["CRUK0046_1"], ["CRUK0049_1"], ["CRUK0096_1"], ["CRUK0007_1"], ["CRUK0072_1"], ["CRUK0043_1"], ["CRUK0089_1"], ["CRUK0088_1"], ["CRUK0039_1"], ["CRUK0086_1"], ["CRUK0048_1"], ["CRUK0033_1"], ["CRUK0047_1"], ["CRUK0030_1"], ["CRUK0037_1"], ["CRUK0008_1"], ["CRUK0018_1"], ["CRUK0041_1"], ["CRUK0080_1"], ["CRUK0084_1"], ["CRUK0028_1"], ["CRUK0025_1"], ["CRUK0060_1"], ["CRUK0091_1"], ["CRUK0050_1"], ["CRUK0083_1"], ["CRUK0040_1"], ["CRUK0092_1"], ["CRUK0021_1"], ["CRUK0094_1"], ["CRUK0079_1"], ["CRUK0090_1"], ["CRUK0029_1"], ["CRUK0057_1"], ["CRUK0003_1"], ["CRUK0100_1"], ["CRUK0026_1"], ["CRUK0045_1", "CRUK0020_1", "CRUK0020_2"], ["CRUK0024_1", "CRUK0024_2"], ["CRUK0066_1", "CRUK0076_1"], ["CRUK0006_2", "CRUK0006_1", "CRUK0006_3"], ["CRUK0023_1", "CRUK0023_2", "CRUK0015_1", "CRUK0064_1", "CRUK0056_1"]]}
diff --git a/display_tree.js b/display_tree.js
index d267b66..075007b 100755
--- a/display_tree.js
+++ b/display_tree.js
@@ -305,7 +305,7 @@ function displayTree(div_id, tree_label, tree_data, target_gene, target_drug, dr
     max_genes_in_list = 4
     node.on('mousemove', function(d) {
       // Compute html info.
-      if (d.parent) {
+      if (d.parent || d.data.gene_event_categories) {
         html_info = ""
         if (d.data.matching_label) {
           html_info += "<b>Matching label:</b> " + d.data.matching_label + "<br/>"
@@ -331,9 +331,10 @@ function displayTree(div_id, tree_label, tree_data, target_gene, target_drug, dr
             html_info += "<br/>"
           }
         }
-      } else {
+      } else if (!(d.parent)){
         html_info = "root"
       }
+
       // Populate tooltip.
       tooltip 
         .html(html_info)
diff --git a/oncotreevis.js b/oncotreevis.js
index c87ba70..7dedc4f 100644
--- a/oncotreevis.js
+++ b/oncotreevis.js
@@ -1,7 +1,26 @@
 ///////////////////////
 //// Main function ////
 ///////////////////////
+function async_func(input, callback) {
+  setTimeout(function () {
+    callback(input);
+    //document.body.style.cursor = "auto"
+  }, 0);
+  //document.body.style.cursor = "wait"
+}     
+    
 function oncotreeVIS(data, container_div_id) {
+  var args = {
+    "data": data,
+    "container_div_id": container_div_id,
+  }
+  async_func(args, oncotreeVIS_slow)
+}
+
+function oncotreeVIS_slow(args) {
+  data = args.data 
+  container_div_id = args.container_div_id
+
   var num_max_node_colors = 10
   var tree_cohort_div_id = "tree_cohort"
   var tree_info_div_id = "tree_info"
@@ -194,7 +213,10 @@ function oncotreeVIS(data, container_div_id) {
 
   // kNN
   knn_json = {}
-  if(mapSize(trees) < 200) {
+  if ("pairwise_subclone_distances" in data) {
+    // TODO
+  }
+  else if (mapSize(trees) < 1500 && mapSize(cohort_node_color_map) < 50) {
     for (let sample_1 in trees) {
       tree_1 = trees[sample_1]["tree"]
       //var matching_tree_ids = Object.keys(trees)
@@ -215,6 +237,7 @@ function oncotreeVIS(data, container_div_id) {
           const [nodes_1, links_1, max_depth_1] = getJSONNodes(sample_1, tree_1)
           const [nodes_2, links_2, max_depth_2] = getJSONNodes(sample_2, tree_2)
           const max_depth = Math.max(max_depth_1, max_depth_2)
+          const max_similarity = Math.max(nodes_1.length, nodes_2.length)
           nodes = nodes_1.concat(nodes_2)
           links = links_1.concat(links_2)
           for (let pair of matching_node_pairs) {
@@ -229,7 +252,7 @@ function oncotreeVIS(data, container_div_id) {
             "sample_2": sample_2,
             "nodes": nodes,
             "links": links,
-            "similarity": matching_node_pairs.length,
+            "similarity": matching_node_pairs.length / max_similarity,
             "max_depth": max_depth
           }
         } 
@@ -239,7 +262,6 @@ function oncotreeVIS(data, container_div_id) {
   data["matching_trees"] = knn_json
   // END Populate additional data.
 
-
   var useful_variables = {
     "tree_cohort_div_id": tree_cohort_div_id, 
     "tree_info_div_id": tree_info_div_id,
@@ -255,7 +277,7 @@ function oncotreeVIS(data, container_div_id) {
   addHTMLElements(container_div_id, useful_variables)
   
   // Populate with tree data. 
-  populateTreeView(useful_variables)
+  populateTreeView_slow(useful_variables)
 }
 
 function getJSONNodes(sample_name, tree_json) {
@@ -420,7 +442,7 @@ function addHTMLElements(container_div_id, args) {
   outer_div.appendChild(tree_view_div)
    
   // Heatmap view buttons.
-  if ("pairwise_distances" in args.data) { 
+  if ("pairwise_tree_distances" in args.data) { 
     var heatmap_view_button = document.createElement('button')
     heatmap_view_button.className = "button-15"
     heatmap_view_button.addEventListener('click', ()=>{ populateHeatmapView(args) })
@@ -458,9 +480,9 @@ function addHTMLElements(container_div_id, args) {
   tree_info_div.style.borderRadius = "8px"
   tree_info_div.style.fontSize = "13px"
   tree_info_div.style.position = "fixed"
-  tree_info_div.style.width = "24%"
+  tree_info_div.style.width = "max(24%, 300px)" 
   //tree_info_div.style.maxWidth = "430px"
-  tree_info_div.style.minWidth = "300px"
+  //tree_info_div.style.minWidth = "300px"
   tree_info_div.style.padding = "7px"
   tree_info_div.style.float = "right"
   //tree_info_div.style.left = "calc(73% + 2px)"
@@ -481,7 +503,13 @@ function addHTMLElements(container_div_id, args) {
 ///////////////////
 //// Tree view ////
 ///////////////////
-function populateTreeView(args){
+function populateTreeView(args) {
+  populateTreeView_slow(args)
+  //async_func(args, populateTreeView_slow)
+  //document.body.style.cursor = "wait"
+}
+
+function populateTreeView_slow(args){
   // Arguments:
   // trees: tree information; 
   // clusters: list of lists with sample names which match the tree keys;
@@ -615,7 +643,6 @@ function populateTreeView(args){
       container.css('top', Math.max(0, initial_position - scroll_offset));
     });
   });
-
 }
 
 //////////////
@@ -840,6 +867,9 @@ function updateGeneStates(gene_events_map, parent_gene_states) {
               new_gene_states[gene][new_event_type] =  old_value + ";" + new_value
             }
           } else {
+            if (!(gene in new_gene_states)) {
+              new_gene_states[gene] = {}
+            }
             new_gene_states[gene][new_event_type] = new_value
           }
         }
@@ -1114,32 +1144,32 @@ function showTreeInfo(sample_name, args) {
   }
 
   // kNN matching trees.
-  if (knn && mapSize(knn)) { 
-    var header_knn = createInfoHeader("<b>K-nearest tree neighbors</b>")
-    header_knn.style.direction = "ltr"
-    var info_icon = createInfoTooltip("fa fa-question-circle")
-    info_text = "K-nearest matching trees to the selected tree, computed using a greedy approximation algorithm for the maximum matching problem with ordering constraints."
-    addInfoBoxToElement(info_icon, info_text, bg_color="#353935", width=150, margin_left="", position="left", line_height="20px")
-    header_knn.appendChild(info_icon)
-
-    tree_info_div.appendChild(header_knn)
-
-    var knn_box_id = "knn"
-    var knn_box_div = createDivContainer(knn_box_id)
-    knn_box_div.style.direction = "ltr"
-    knn_box_div.style.display = 'none'
-    tree_info_div.appendChild(knn_box_div)
-
+  var header_knn = createInfoHeader("<b>K-nearest tree neighbors</b>")
+  header_knn.style.direction = "ltr"
+  var info_icon = createInfoTooltip("fa fa-question-circle")
+  info_text = "K-nearest matching trees to the selected tree, computed using a greedy approximation algorithm for the maximum matching problem with ordering constraints."
+  addInfoBoxToElement(info_icon, info_text, bg_color="#353935", width=150, margin_left="", position="left", line_height="20px")
+  header_knn.appendChild(info_icon)
+  tree_info_div.appendChild(header_knn)
+
+  var knn_box_id = "knn"
+  var knn_box_div = createDivContainer(knn_box_id)
+  knn_box_div.style.direction = "ltr"
+  knn_box_div.style.display = 'none'
+  tree_info_div.appendChild(knn_box_div)
+  if (knn && mapSize(knn)) {
     knn_keys = Object.keys(knn)
     sample_matches = knn_keys.filter((key) => key.startsWith(sample_name))
     sample_matches.sort((key_1, key_2) => knn[key_2]["similarity"] - knn[key_1]["similarity"])
     for(let key of sample_matches) {
       async_display_tree_matching(knn_box_id, knn[key])
     }
-
-    header_knn.appendChild(createExpandBox(knn_box_id))
-    appendLineBreak(tree_info_div)
+  } else {
+    knn_box_div.innerHTML = "<i>KNN not computed either because node `matching_label` attributes are missing or the number of trees " +
+        "is too large. Please provide precomputed pairwise subclone distances in the `pairwise_subclone_distances` field of your input JSON.</i><br/>"
   }
+  header_knn.appendChild(createExpandBox(knn_box_id))
+  appendLineBreak(tree_info_div)
 
   // Add event listeners after the DOM is complete. 
   $('.gene_selection, .drug_selection').on('change', 
@@ -1351,7 +1381,7 @@ function updateTree(event) {
 
 function populateGeneDrugInfoHTML(target_gene, gene_drug_map) {
   if (target_gene == "") {
-    return "No target gene selected.<br/>"
+    return "<i>No target gene selected.</i><br/>"
   }
   var drugs = gene_drug_map.get(target_gene)
   if (!(gene_drug_map.has(target_gene))) {
@@ -1752,6 +1782,12 @@ function getColorCodesTable(map) {
 //// Heatmap view ////
 //////////////////////
 function populateHeatmapView(args) {
+  populateHeatmapView_slow(args)
+  //async_func(args, populateHeatmapView_slow)
+  //document.body.style.cursor = "wait"
+}
+
+function populateHeatmapView_slow(args) {
   // Canvas.
   var tree_cohort_div_id = args.tree_cohort_div_id
   div_tree_cohort = document.getElementById(tree_cohort_div_id)
@@ -1768,7 +1804,7 @@ function populateHeatmapView(args) {
 
   // Data.
   data = args.data
-  distances = data["pairwise_distances"]
+  distances = data["pairwise_tree_distances"]
   sample_list = Object.keys(data["trees"])
   clusters = [sample_list]
   if ("clusters" in data) {
@@ -2028,6 +2064,12 @@ function MDS(distances, dimensions) {
 }
 
 function populate2DView(args) {
+  populate2DView_slow(args)
+  //async_func(args, populate2DView_slow)
+  //document.body.style.cursor = "wait"
+} 
+
+function populate2DView_slow(args) {
   // Canvas.
   var tree_cohort_div_id = args.tree_cohort_div_id
   div_tree_cohort = document.getElementById(tree_cohort_div_id)
@@ -2057,8 +2099,7 @@ function populate2DView(args) {
       "<br/>to visualize additional information<br/>about the corresponding mutation tree.</i></div>"
 
   // Data.
-  distances = args.data["pairwise_distances"]
-  var opt = {epsilon: 10}; // epsilon is learning rate (10 = default)
+  distances = args.data["pairwise_tree_distances"]
   var sample_id_map = {}
   distances.forEach(function(item) {
     sample = item["sample_1"]