COPASI 4.24 (Build 197)

The COPASI team announces the immediate availability of the stable release COPASI 4.24 (Build 197).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is mainly a bug fix release with some GUI improvements:

• Graphical User Interface
  • Implemented a new 3d bar graph view of matrixes allowing for better selection of interesting values. The new view also avoids OpenGL issues due to incomplete graphic card support of the OS.
  • Improved issue display in the object browser which did not recognize missing expressions for entities of type ODE and occasionally marked missing initial expressions when not required.
  • Improved display of advanced method parameters. If advanced parameter usage is indicated in the preferences they will be shown last. If it is not selected non advanced parameters which are not at their value will be shown to inform the user.
• SBML
  • Models which explicitely reference Avogadro's number can now be exported to SBML.

Release Date: July 30, 2018

More information can be found in the changelog.

COPASI 4.23 (Build 184)

The COPASI team announces the immediate availability of the stable release COPASI 4.23 (Build 184).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This release includes many new features:

New Features

• Graphical User Interface
  • Model Merging: COPASI allows to add a second model and to merge its content with the existing one.
  • Compartment dimensionality may now be specified as: volume, area, length, or dimensionless.
  • Problems (Errors, Warnings) of the model are no marked in the object browser at the problematic entity.
  • Enhanced Unit Support for kinetic parameters.
  • Import and export of Combine Archive is now supported.
  • The full and reduced Jacobian of the current model state are now shown under Model/Mathematical/Matrices.
  • Enable copying table and annotated matrix items to the clipboard.
  • A warning is now raised when loading an invalid model (i.e: one that does not compile) and the problematic
    entity is marked in the browser pane.
  • Added ability to add COPASI version, current date/time, first name, last name, email and organization as
    well as line breaks to a reports.
  • Allow for the selection of matrices in Object Browser expert mode.
  • Plots can be associated with tasks similar to the existing report association
  • The direct dependencies, i.e, the objects which are directly effected by changes or removal of an
    entity are now displayed on all modeling entities.
• Simulation Engine
  • COPASI supports Stochastic Differential Equations (SDEs). It is possible to add noise to reactions and
    entities (compartments, species, and global quantities) determined by ODEs.
    Release Date: April 18, 2018

More information can be found in the changelog.

COPASI 4.22 (Build 170)

The COPASI team announces the immediate availability of the stable release COPASI 4.22 (Build 170).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. The main improvement in this release is the significantly increased performance.

Release Date: November 10, 2017

More information can be found in the changelog.

COPASI 4.21 (Build 166)

The COPASI team announces the immediate availability of the stable release COPASI 4.21 (Build 166).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the
Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. The main improvement in this release is the significantly increased performance.

Release Date: October 09, 2017

More information can be found in the changelog.

COPASI 4.20 (Build 158)

The COPASI team announces the immediate availability of the stable release COPASI 4.20 (Build 158).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is mainly a bug fix release and with the following new features:

• Graphical User Interface (CopasiUI)
  • It is now possible to export the rendered mathematical expressions to a PDF document.
  • The application window remembers the size of the window and the with of the left browser pane to avoid frequent adjustment by the user.
  • Plots can now be activated and deactivated in the plot itself.
  • When an experimental data file is not found at the expected location COPASI allows now specify a new location by opening a file open dialog.
• Simulation Engine
  • The Avogadro symbol can now be used in user defined functions.

Release Date: July 31, 2017

More information can be found in the changelog.

COPASI 4.19 (Build 140) Released

The COPASI team announces the immediate availability of the stable release COPASI 4.19 (Build 140).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is a bug fix release which fixes an access violation crash.

Release Date: January 12, 2017

More information can be found in the changelog.

COPASI 4.18 (Build 136) Released

The COPASI team announces the immediate availability of the stable release COPASI 4.18 (Build 136).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge. This is a bug fix release which fixes an access violation crash.

Release Date: November 28, 2016

More information can be found in the changelog.

COPASI 4.17 (Build 135) Released

The COPASI team announces the immediate availability of the stable
release COPASI 4.17 (Build 135).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge.

Release Date: November 21, 2016

New Features since COPASI 4.16 (Build 104)

• Graphical User Interface (CopasiUI)
  • Support for user defined units.
  • Extended unit selection options for time, volume and quantity of the model. These extended options include user defined units.
  • Unit support for Global Quantities.
  • Undo and redo support for all model changes.
  • Improved user interface to method parameters.
  • Selection of matrix and vector elements by name in addition to the index for plots, reports, and in mathematical expressions.
  • Support for contour plots.
  • Sorting off all analysis result tables is now enabled where appropriate.
  • The MCA results contain now information whether the summation theorems are violated or not allowing the user to easily evaluate the numerical accuracy of the result.
  • It is now possible to the select the units of the rate low for a reaction as either amount per time or concentration per time. If concentration per time is selected and the reaction participates in multiple compartments the scaling compartment can be selected.
• Simulation Engine
  • Added support for arbitrary events to the Stochastic Direct Method.
  • New hybrid simulation algorithm: (Hybrid RK-45) which supports arbitrary discrete events and user defined ODEs. Additionally, the user can specify which reaction are treated continuously and which are treated discretely. This algorithm passes the SBML semantic test suite and stochastic suite.
  • It is now possible to report or plot only the internal steps taken by the integration algorithm in the trajectory task.
• SBML
  • Full support for SBML Level 3.1 event semantics
  • Import and export of unit definitions.
  • SBOTerms are no imported and displayed as part of the MIRIAM annotation. On export a the first SBOTerm of the MIRIAM annotation is used if the SBML entity does not have the SBOTerm set.

A list of resolved issues can be found in the
[changelog]({{ site.baseurl }}/Support/Change_History/COPASI_4_17_Build_135/).

COPASI 4.16 (Build 104) Released

New Features since COPASI 4.15 (Build 95)

• Graphical User Interface (CopasiUI)
  • The copy to next feature in the Experimental data description
    dialog is now able to handle the situation were the target
    experiment has less columns than the copied one.
• Simulation Engine
  • The Gamma distribution and the Poisson distribution are now
    accessible in mathematical expressions and exported to SBML.
• SBML
  • COPASI now exports the SBML L1V1 legacy format.

A list of resolved issues can be found in the
changelog.

COPASI 4.15 (Build 95) Released

Build-95

- adjust event creation to deal with missing data