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DESCRIPTION
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DESCRIPTION
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Package: wnl
Version: 0.8.1
Title: Minimization Tool for Pharmacokinetic-Pharmacodynamic Data
Analysis
Description: This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.
Depends: R (>= 3.5.0), numDeriv
Author: Kyun-Seop Bae [aut]
Maintainer: Kyun-Seop Bae <[email protected]>
Copyright: 2017-, Kyun-Seop Bae
License: GPL-3
NeedsCompilation: no
LazyLoad: yes
Repository: CRAN
URL: https://cran.r-project.org/package=wnl
Packaged: 2024-06-01 02:55:09 UTC; Kyun-SeopBae
Date/Publication: 2024-06-01 03:10:02 UTC