diff --git a/setup.py b/setup.py
index 58cdce92..393eac28 100644
--- a/setup.py
+++ b/setup.py
@@ -55,7 +55,7 @@ def add_version_constraint(package_name, version):
     ],
     package_dir={"": "src"},
     packages=setuptools.find_packages(where="src"),
-    python_requires=">=3.6",
+    python_requires=">=3.10",
     install_requires=[
         add_version_constraint("deephaven-server", dh_version),
         "pandas",