diff --git a/packages/metro-file-map/package.json b/packages/metro-file-map/package.json
index a97dea57d..726c2e374 100644
--- a/packages/metro-file-map/package.json
+++ b/packages/metro-file-map/package.json
@@ -13,7 +13,6 @@
   },
   "license": "MIT",
   "dependencies": {
-    "anymatch": "^3.0.3",
     "debug": "^2.2.0",
     "fb-watchman": "^2.0.0",
     "flow-enums-runtime": "^0.0.6",
diff --git a/packages/metro-file-map/src/watchers/FSEventsWatcher.js b/packages/metro-file-map/src/watchers/FSEventsWatcher.js
index fe3e16bbe..a0e9d7f70 100644
--- a/packages/metro-file-map/src/watchers/FSEventsWatcher.js
+++ b/packages/metro-file-map/src/watchers/FSEventsWatcher.js
@@ -13,9 +13,12 @@ import type {ChangeEventMetadata} from '../flow-types';
 // $FlowFixMe[untyped-type-import]
 import type {FSEvents} from 'fsevents';
 
-import {isIncluded, recReaddir, typeFromStat} from './common';
-// $FlowFixMe[untyped-import] - anymatch
-import anymatch from 'anymatch';
+import {
+  isIncluded,
+  posixPathMatchesPattern,
+  recReaddir,
+  typeFromStat,
+} from './common';
 import EventEmitter from 'events';
 import {promises as fsPromises} from 'fs';
 import * as path from 'path';
@@ -63,7 +66,11 @@ export default class FSEventsWatcher extends EventEmitter {
 
   constructor(
     dir: string,
-    opts: $ReadOnly<{
+    {
+      ignored,
+      glob,
+      dot,
+    }: $ReadOnly<{
       ignored: ?RegExp,
       glob: string | $ReadOnlyArray<string>,
       dot: boolean,
@@ -78,10 +85,12 @@ export default class FSEventsWatcher extends EventEmitter {
 
     super();
 
-    this.dot = opts.dot || false;
-    this.ignored = opts.ignored;
-    this.glob = Array.isArray(opts.glob) ? opts.glob : [opts.glob];
-    this.doIgnore = opts.ignored ? anymatch(opts.ignored) : () => false;
+    this.dot = dot || false;
+    this.ignored = ignored;
+    this.glob = Array.isArray(glob) ? glob : [glob];
+    this.doIgnore = ignored
+      ? (filePath: string) => posixPathMatchesPattern(ignored, filePath)
+      : () => false;
 
     this.root = path.resolve(dir);
 
diff --git a/packages/metro-file-map/src/watchers/common.js b/packages/metro-file-map/src/watchers/common.js
index 099ba1626..5bfc97b81 100644
--- a/packages/metro-file-map/src/watchers/common.js
+++ b/packages/metro-file-map/src/watchers/common.js
@@ -19,8 +19,6 @@
 import type {ChangeEventMetadata} from '../flow-types';
 import type {Stats} from 'fs';
 
-// $FlowFixMe[untyped-import] - Write libdefs for `anymatch`
-const anymatch = require('anymatch');
 // $FlowFixMe[untyped-import] - Write libdefs for `micromatch`
 const micromatch = require('micromatch');
 const platform = require('os').platform();
@@ -74,8 +72,10 @@ export const assignOptions = function (
   if (!Array.isArray(watcher.globs)) {
     watcher.globs = [watcher.globs];
   }
-  watcher.doIgnore =
-    opts.ignored != null ? anymatch(opts.ignored) : () => false;
+  const ignored = watcher.ignored;
+  watcher.doIgnore = ignored
+    ? filePath => ignored.test(toPosixSeparators(filePath))
+    : () => false;
 
   if (opts.watchman == true && opts.watchmanPath != null) {
     watcher.watchmanPath = opts.watchmanPath;
@@ -105,6 +105,26 @@ export function isIncluded(
   return micromatch.some(relativePath, globs, {dot});
 }
 
+const toPosixSeparators: (filePath: string) => string =
+  path.sep === '/'
+    ? filePath => filePath
+    : filePath => filePath.replaceAll(path.sep, '/');
+
+/**
+ * Whether the given filePath matches the given RegExp, after converting
+ * (on Windows only) system separators to posix separators.
+ *
+ * Conversion to posix is for backwards compatibility with the previous
+ * anymatch matcher, which normlises all inputs[1]. This may not be consistent
+ * with other parts of metro-file-map.
+ *
+ * [1]: https://github.com/micromatch/anymatch/blob/3.1.1/index.js#L50
+ */
+export const posixPathMatchesPattern = (
+  pattern: RegExp,
+  filePath: string,
+): boolean => pattern.test(toPosixSeparators(filePath));
+
 /**
  * Traverse a directory recursively calling `callback` on every directory.
  */
@@ -117,8 +137,13 @@ export function recReaddir(
   errorCallback: Error => void,
   ignored: ?RegExp,
 ) {
-  walker(dir)
-    .filterDir(currentDir => !anymatch(ignored, currentDir))
+  const walk = walker(dir);
+  if (ignored) {
+    walk.filterDir(
+      (currentDir: string) => !posixPathMatchesPattern(ignored, currentDir),
+    );
+  }
+  walk
     .on('dir', normalizeProxy(dirCallback))
     .on('file', normalizeProxy(fileCallback))
     .on('symlink', normalizeProxy(symlinkCallback))