diff --git a/CHANGELOG.md b/CHANGELOG.md
index 6ee6b50b2..3715c298e 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -11,6 +11,7 @@
 * Update fee/fine actions column UX for accessibility. Refs UIU-3027.
 * Rename permission after BE changes. Refs UIU-3309.
 * Change import of `exportToCsv` from `stripes-util` to `stripes-components`. Refs UIU-3202.
+* Add ability to create/edit role assignments for all of a user's affiliations. Refs UIU-3179.
 
 ## [11.0.10](https://github.com/folio-org/ui-users/tree/v11.0.10) (2025-01-10)
 [Full Changelog](https://github.com/folio-org/ui-users/compare/v11.0.9...v11.0.10)
diff --git a/src/components/EditSections/EditUserRoles/EditUserRoles.js b/src/components/EditSections/EditUserRoles/EditUserRoles.js
index 9ad7a544b..cb2cda71c 100644
--- a/src/components/EditSections/EditUserRoles/EditUserRoles.js
+++ b/src/components/EditSections/EditUserRoles/EditUserRoles.js
@@ -1,22 +1,41 @@
-import React, { useMemo, useState } from 'react';
+import React, { useEffect, useMemo, useState } from 'react';
 import { useIntl, FormattedMessage } from 'react-intl';
 import { withRouter } from 'react-router';
 import PropTypes from 'prop-types';
 import { isEmpty } from 'lodash';
 import { FieldArray } from 'react-final-form-arrays';
 import { OnChange } from 'react-final-form-listeners';
-import { IfPermission } from '@folio/stripes/core';
+
+import { IfPermission, useStripes } from '@folio/stripes/core';
 import { Accordion, Headline, Badge, Row, Col, List, Button, Icon, ConfirmationModal } from '@folio/stripes/components';
-import { useAllRolesData } from '../../../hooks';
+
+import { useAllRolesData, useUserAffiliations } from '../../../hooks';
+import AffiliationsSelect from '../../AffiliationsSelect/AffiliationsSelect';
+import IfConsortium from '../../IfConsortium';
+import IfConsortiumPermission from '../../IfConsortiumPermission';
 import UserRolesModal from './components/UserRolesModal/UserRolesModal';
+import { isAffiliationsEnabled } from '../../util/util';
 import { filtersConfig } from './helpers';
 
-function EditUserRoles({ accordionId, form:{ change }, setAssignedRoleIds, assignedRoleIds }) {
+function EditUserRoles({ accordionId, form:{ change }, user, setAssignedRoleIds, assignedRoleIds, setTenantId, tenantId }) {
+  const stripes = useStripes();
   const [isOpen, setIsOpen] = useState(false);
   const [unassignModalOpen, setUnassignModalOpen] = useState(false);
   const intl = useIntl();
 
-  const { isLoading: isAllRolesDataLoading, allRolesMapStructure } = useAllRolesData();
+  const {
+    affiliations,
+    isFetching: isAffiliationsFetching,
+  } = useUserAffiliations({ userId: user.id }, { enabled: isAffiliationsEnabled(user) });
+
+  const { isLoading: isAllRolesDataLoading, allRolesMapStructure, refetch } = useAllRolesData({ tenantId });
+
+  useEffect(() => {
+    if (!affiliations.some(({ tenantId: assigned }) => tenantId === assigned)) {
+      setTenantId(stripes.okapi.tenant);
+    }
+    refetch();
+  }, [affiliations, stripes.okapi.tenant, tenantId]);
 
   const changeUserRoles = (roleIds) => {
     change('assignedRoleIds', roleIds);
@@ -101,6 +120,18 @@ function EditUserRoles({ accordionId, form:{ change }, setAssignedRoleIds, assig
           displayWhenClosed={<Badge>{assignedRoleIds.length}</Badge>}
         >
           <Row>
+            <IfConsortium>
+              <IfConsortiumPermission perm="consortia.user-tenants.collection.get">
+                {Boolean(affiliations?.length) && (
+                  <AffiliationsSelect
+                    affiliations={affiliations}
+                    onChange={setTenantId}
+                    isLoading={isAllRolesDataLoading || isAffiliationsFetching}
+                    value={tenantId}
+                  />
+                )}
+              </IfConsortiumPermission>
+            </IfConsortium>
             {renderUserRoles()}
             <IfPermission perm="ui-authorization-roles.users.settings.manage">
               <Button data-testid="add-roles-button" onClick={() => setIsOpen(true)}><FormattedMessage id="ui-users.roles.addRoles" /></Button>
diff --git a/src/components/Wrappers/withUserRoles.js b/src/components/Wrappers/withUserRoles.js
index a25317728..9f6693b42 100644
--- a/src/components/Wrappers/withUserRoles.js
+++ b/src/components/Wrappers/withUserRoles.js
@@ -10,13 +10,14 @@ const withUserRoles = (WrappedComponent) => (props) => {
   const { okapi, config } = useStripes();
   // eslint-disable-next-line react/prop-types
   const userId = props.match.params.id;
+  const [tenantId, setTenantId] = useState(okapi.tenant);
   const [assignedRoleIds, setAssignedRoleIds] = useState([]);
   const [initialAssignedRoleIds, setInitialAssignedRoleIds] = useState([]);
   const [isCreateKeycloakUserConfirmationOpen, setIsCreateKeycloakUserConfirmationOpen] = useState(false);
   const callout = useCallout();
   const sendErrorCallout = error => showErrorCallout(error, callout.sendCallout);
 
-  const { mutateAsync: createKeycloakUser } = useCreateAuthUserKeycloak(sendErrorCallout, { tenantId: okapi.tenant });
+  const { mutateAsync: createKeycloakUser } = useCreateAuthUserKeycloak(sendErrorCallout, { tenantId });
 
   const { isLoading: isAllRolesDataLoading, allRolesMapStructure } = useAllRolesData();
 
@@ -28,7 +29,7 @@ const withUserRoles = (WrappedComponent) => (props) => {
   const ky = useOkapiKy();
   const api = ky.extend({
     hooks: {
-      beforeRequest: [(req) => req.headers.set('X-Okapi-Tenant', okapi.tenant)]
+      beforeRequest: [(req) => req.headers.set('X-Okapi-Tenant', tenantId)]
     }
   });
 
@@ -57,7 +58,7 @@ const withUserRoles = (WrappedComponent) => (props) => {
   },
   // Adding api, searchParams to deps causes infinite callback call. Listed deps are enough to track changes.
   // eslint-disable-next-line react-hooks/exhaustive-deps
-  [userId, isAllRolesDataLoading, setAssignedRoleIdsOnLoad]);
+  [userId, isAllRolesDataLoading, setAssignedRoleIdsOnLoad, tenantId]);
 
   const updateUserRoles = (roleIds) => api.put(
     `roles/users/${userId}`, { json: {
@@ -116,6 +117,8 @@ const withUserRoles = (WrappedComponent) => (props) => {
 
   return <WrappedComponent
     {...props}
+    tenantId={tenantId}
+    setTenantId={setTenantId}
     assignedRoleIds={assignedRoleIds}
     setAssignedRoleIds={setAssignedRoleIds}
     isCreateKeycloakUserConfirmationOpen={isCreateKeycloakUserConfirmationOpen}
diff --git a/src/hooks/useAllRolesData/useAllRolesData.js b/src/hooks/useAllRolesData/useAllRolesData.js
index 542a07077..913a8cf14 100644
--- a/src/hooks/useAllRolesData/useAllRolesData.js
+++ b/src/hooks/useAllRolesData/useAllRolesData.js
@@ -13,13 +13,14 @@ import { useQuery } from 'react-query';
  *  - isSuccess: A boolean indicating if the data fetch was successful.
  */
 
-function useAllRolesData() {
+function useAllRolesData(options = {}) {
+  const { tenantId } = options;
   const stripes = useStripes();
-  const ky = useOkapiKy();
+  const ky = useOkapiKy({ tenant: tenantId || stripes.okapi.tenant });
 
   const [namespace] = useNamespace();
 
-  const { data, isLoading, isSuccess } = useQuery([namespace, 'user-roles'], () => {
+  const { data, isLoading, isSuccess, refetch } = useQuery([namespace, 'user-roles'], () => {
     return ky.get(`roles?limit=${stripes.config.maxUnpagedResourceCount}&query=cql.allRecords=1 sortby name`).json();
   }, { enabled: stripes.hasInterface('roles') });
 
@@ -32,7 +33,7 @@ function useAllRolesData() {
     return rolesMap;
   }, [data]);
 
-  return { data, isLoading, allRolesMapStructure, isSuccess };
+  return { data, isLoading, allRolesMapStructure, isSuccess, refetch };
 }
 
 export default useAllRolesData;
diff --git a/src/views/UserEdit/UserEdit.js b/src/views/UserEdit/UserEdit.js
index 72dde2f43..63ae4ba32 100644
--- a/src/views/UserEdit/UserEdit.js
+++ b/src/views/UserEdit/UserEdit.js
@@ -459,6 +459,8 @@ class UserEdit extends React.Component {
       location,
       match: { params },
       isCreateKeycloakUserConfirmationOpen,
+      setTenantId,
+      tenantId,
       setAssignedRoleIds,
       assignedRoleIds
     } = this.props;
@@ -497,6 +499,8 @@ class UserEdit extends React.Component {
         isCreateKeycloakUserConfirmationOpen={isCreateKeycloakUserConfirmationOpen}
         onCancelKeycloakConfirmation={this.onCompleteEdit}
         confirmCreateKeycloakUser={() => this.props.confirmCreateKeycloakUser(this.onCompleteEdit)}
+        setTenantId={setTenantId}
+        tenantId={tenantId}
         setAssignedRoleIds={setAssignedRoleIds}
         assignedRoleIds={assignedRoleIds}
       />
diff --git a/src/views/UserEdit/UserForm.js b/src/views/UserEdit/UserForm.js
index 5cb0118e2..e58607ce7 100644
--- a/src/views/UserEdit/UserForm.js
+++ b/src/views/UserEdit/UserForm.js
@@ -472,6 +472,9 @@ class UserForm extends React.Component {
                           setButtonRef={this.setButtonRef}
                         /> : <EditUserRoles
                           form={form}
+                          user={initialValues}
+                          setTenantId={this.props.setTenantId}
+                          tenantId={this.props.tenantId}
                           setAssignedRoleIds={this.props.setAssignedRoleIds}
                           assignedRoleIds={this.props.assignedRoleIds}
                           accordionId="userRoles"