LogR and BAF

[tanasa]

Dear Gavin,

We are very happy to use the algorithms that your group has developed for mapping CNA and LOH in tumor samples, especially TitanCNA. I would appreciate having a piece of advice :

Given the output from TitanCNA, which criteria shall I apply on LogR and BAF in order to annotate the CNA/LOH as : homozygous deletion, heterozygous deletion, diploid, copy number gain, copy-number amplification, copy-number LOH ?

I am looking forward to hearing from you,

Thanks so much,

Bogdan