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Question about -ej option in macs #33

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cdquinto opened this issue Jul 9, 2015 · 3 comments
Open

Question about -ej option in macs #33

cdquinto opened this issue Jul 9, 2015 · 3 comments

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@cdquinto
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cdquinto commented Jul 9, 2015

Hello again,

When the option -ej is used, what happens to the size of population j? Is it the same as specified in the command?
In particular, I want to know if these 2 commands will have the same behavior.
Command 1:
macs 10 100000 -t 0.004 -r 0.004 -h 1e5 -I 2 5 5 -n 1 2 -n 2 2 -ej 0.0003 2 1 -en 0.000300001 1 2
-en 0.00005 1 1
Command 2:
macs 10 100000 -t 0.004 -r 0.004 -h 1e5 -I 2 5 5 -n 1 2 -n 2 2 -ej 0.0003 2 1 -en 0.00005 1 1

Thank you

@gchen98
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gchen98 commented Jul 9, 2015

For population join events all chromosomes from the population specified
in the first argument are migrated to the population specfied in the
second argument.

On 07/08/2015 06:08 PM, cdquinto wrote:

Hello again,

When the option -ej is used, what happens to the size of population j?
Is it the same as specified in the command?
In particular, I want to know if these 2 commands will have the same
behavior.
Command 1:
macs 10 100000 -t 0.004 -r 0.004 -h 1e5 -I 2 5 5 -n 1 2 -n 2 2 -ej
0.0003 2 1 -en 0.000301 1 2
-en 0.00005 1 1
Command 2:
macs 10 100000 -t 0.004 -r 0.004 -h 1e5 -I 2 5 5 -n 1 2 -n 2 2 -ej
0.0003 2 1 -en 0.00005 1 1

Thank you


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#33.

@cdquinto
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cdquinto commented Jul 9, 2015 via email

@gchen98
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gchen98 commented Jul 9, 2015

Yes. It receives migrants from 2, but the population size is an
independent parameter.

On 07/08/2015 10:03 PM, cdquinto wrote:

In my example,

macs 10 100000 -t 0.004 -r 0.004 -h 1e5 -I 2 5 5 -n 1 2 -n 2 2 -ej 0.0003 2
1

Population 1 has size 2 before receiving the chromosomes from population 2.

After these populations are joined, does population 1 still has size 2?


Reply to this email directly or view it on GitHub
#33 (comment).

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