DESCRIPTION

Package: PrecisionTrialDrawer
Type: Package
Title: A Tool to Analyze and Design NGS Based Custom Gene Panels
Version: 1.13.1
Date: 2022-09-19
Authors@R: 
    c(person(given = "Giorgio",
            family = "Melloni",
            role = c("aut", "cre"),
            email = "melloni.giorgio@gmail.com",
            comment = c(ORCID = "0000-0001-6371-1334")),
    person(given = "Alessandro",
            family = "Guida",
            role = c("aut"),
            email = "aleguida@gmail.com",
            comment = c(ORCID = "0000-0002-7160-750X")))
Description: PrecisionTrialDrawer provides a suite of methods to design umbrella and basket trials for precision oncology. Given a set of targets and possible alteration the user can create projections and sample size estimation based on real public available genomic data.
License: GPL-3
Depends:
    R (>= 3.6)
Imports:
    graphics,
    grDevices,
    stats,
    utils,
    methods,
    cBioPortalData,
    parallel,
    stringr,
    reshape2,
    data.table,
    RColorBrewer,
    BiocParallel,
    magrittr,
    biomaRt,
    XML,
    httr,
    jsonlite,
    ggplot2,
    ggrepel,
    grid,
    S4Vectors,
    IRanges,
    GenomicRanges,
    LowMACAAnnotation,
    googleVis,
    shiny,
    shinyBS,
    DT,
    brglm,
    matrixStats
Suggests:
    BiocStyle,
    knitr,
    rmarkdown,
    dplyr
VignetteBuilder: knitr
biocViews: SomaticMutation, WholeGenome, Sequencing, DataImport, GeneExpression
RoxygenNote: 6.1.0