diff --git a/tensorstore/kvstore/test_matchers.h b/tensorstore/kvstore/test_matchers.h
index 117487343..a81d0cdac 100644
--- a/tensorstore/kvstore/test_matchers.h
+++ b/tensorstore/kvstore/test_matchers.h
@@ -15,6 +15,8 @@
 #ifndef TENSORSTORE_KVSTORE_TEST_MATCHERS_H_
 #define TENSORSTORE_KVSTORE_TEST_MATCHERS_H_
 
+#include <stdint.h>
+
 #include <string>
 #include <type_traits>
 
diff --git a/tensorstore/kvstore/tsgrpc/BUILD b/tensorstore/kvstore/tsgrpc/BUILD
index bb3f88690..4b231452f 100644
--- a/tensorstore/kvstore/tsgrpc/BUILD
+++ b/tensorstore/kvstore/tsgrpc/BUILD
@@ -71,7 +71,6 @@ tensorstore_cc_library(
         "//tensorstore/util:result",
         "@com_github_grpc_grpc//:grpc++",
         "@com_github_grpc_grpc//:grpc++_public_hdrs",
-        "@com_google_absl//absl/log:absl_log",
         "@com_google_absl//absl/status",
         "@com_google_absl//absl/time",
     ],
@@ -215,6 +214,7 @@ tensorstore_cc_test(
         "@com_google_absl//absl/strings:cord",
         "@com_google_absl//absl/strings:str_format",
         "@com_google_absl//absl/synchronization",
+        "@com_google_absl//absl/time",
         "@com_google_googletest//:gtest_main",
     ],
 )
diff --git a/tensorstore/kvstore/tsgrpc/handler_template.h b/tensorstore/kvstore/tsgrpc/handler_template.h
index 3b9c25448..a0cb89f50 100644
--- a/tensorstore/kvstore/tsgrpc/handler_template.h
+++ b/tensorstore/kvstore/tsgrpc/handler_template.h
@@ -15,11 +15,8 @@
 #ifndef TENSORSTORE_KVSTORE_TSGRPC_HANDLER_TEMPLATE_H_
 #define TENSORSTORE_KVSTORE_TSGRPC_HANDLER_TEMPLATE_H_
 
-#include <assert.h>
+#include <cassert>
 
-#include <new>
-
-#include "absl/log/absl_log.h"
 #include "absl/status/status.h"
 #include "grpcpp/grpcpp.h"  // third_party
 #include "grpcpp/server_context.h"  // third_party
@@ -37,7 +34,7 @@ class HandlerBase
 
   HandlerBase(::grpc::CallbackServerContext* grpc_context)
       : grpc_context_(grpc_context) {
-    // This refcount should be adopoted by calling Adopt.
+    // This refcount should be adopted by calling Adopt.
     intrusive_ptr_increment(this);
   }
 
@@ -78,17 +75,18 @@ class Handler : public HandlerBase, public grpc::ServerUnaryReactor {
   Response* response_;
 };
 
-// Handler base class for a stream request.
+// Handler base class for an RPC with a streaming response.
 template <typename RequestProto, typename ResponseProto>
-class StreamHandler : public HandlerBase,
-                      public grpc::ServerWriteReactor<ResponseProto> {
+class StreamServerResponseHandler
+    : public HandlerBase,
+      public grpc::ServerWriteReactor<ResponseProto> {
  public:
   using Request = RequestProto;
   using Response = ResponseProto;
   using Reactor = typename grpc::ServerWriteReactor<ResponseProto>;
 
-  StreamHandler(::grpc::CallbackServerContext* grpc_context,
-                const Request* request)
+  StreamServerResponseHandler(::grpc::CallbackServerContext* grpc_context,
+                              const Request* request)
       : HandlerBase(grpc_context), request_(request) {}
 
   using Reactor::Finish;
@@ -104,6 +102,33 @@ class StreamHandler : public HandlerBase,
   const Request* request_;
 };
 
+// Handler base class for an RPC with a streaming request.
+template <typename RequestProto, typename ResponseProto>
+class StreamClientRequestHandler
+    : public HandlerBase,
+      public grpc::ServerReadReactor<RequestProto> {
+ public:
+  using Request = RequestProto;
+  using Response = ResponseProto;
+  using Reactor = typename grpc::ServerReadReactor<RequestProto>;
+
+  StreamClientRequestHandler(::grpc::CallbackServerContext* grpc_context,
+                             Response* response)
+      : HandlerBase(grpc_context), response_(response) {}
+
+  using Reactor::Finish;
+  void Finish(absl::Status status) {
+    Finish(tensorstore::internal::AbslStatusToGrpcStatus(status));
+  }
+
+  Response* response() { return response_; }
+
+ protected:
+  void OnDone() final { auto adopted = Adopt(); }
+
+  Response* response_;
+};
+
 }  // namespace tensorstore_grpc
 
 #endif  // TENSORSTORE_KVSTORE_TSGRPC_HANDLER_TEMPLATE_H_
diff --git a/tensorstore/kvstore/tsgrpc/kvstore.proto b/tensorstore/kvstore/tsgrpc/kvstore.proto
index 19f5746df..82ecec57d 100644
--- a/tensorstore/kvstore/tsgrpc/kvstore.proto
+++ b/tensorstore/kvstore/tsgrpc/kvstore.proto
@@ -22,10 +22,10 @@ import "tensorstore/kvstore/tsgrpc/common.proto";
 // Proto-api for a remote key-value store
 service KvStoreService {
   /// Attempts to read the specified key.
-  rpc Read(ReadRequest) returns (ReadResponse);
+  rpc Read(ReadRequest) returns (stream ReadResponse);
 
   /// Performs an optionally-conditional write.
-  rpc Write(WriteRequest) returns (WriteResponse);
+  rpc Write(stream WriteRequest) returns (WriteResponse);
 
   /// Performs an optionally-conditional delete.
   rpc Delete(DeleteRequest) returns (DeleteResponse);
@@ -73,6 +73,11 @@ message ReadRequest {
 }
 
 message ReadResponse {
+  // When multiple ReadResponse messages are received, all messages after the
+  // initial message are partial responses, and only the value_part field is
+  // meaningful. In such a case, the value is the catenation of all value_parts
+  // in order.
+
   /// Optionally, a non-ok status message may be returned.
   StatusMessage status = 1;
 
@@ -92,14 +97,22 @@ message ReadResponse {
     /// Indicates a value is present.
     VALUE = 2;
   }
-
   State state = 3;
-  bytes value = 4 [ctype = CORD];
+
+  // Partial value. Only meaningful when state is VALUE.
+  // The actaual value is the catenation of all value_part fields in order.
+  bytes value_part = 4 [ctype = CORD];
 }
 
 /// See tensorstore/kvstore/operations.h
 ///   kvstore::WriteOptions
 message WriteRequest {
+  // When multiple WriteRequest messages are sent, all messages after the
+  // initial message are partial requests, and only the value_part field
+  // is meaningful. In such a case, the value is the catenation of all
+  // value_parts in order.
+
+  /// The key to write.
   bytes key = 1;
 
   /// The write is aborted if the existing generation associated with the
@@ -111,7 +124,10 @@ message WriteRequest {
   /// - The special value of `StorageGeneration::NoValue()` specifies a
   ///   condition that the `key` does not have an existing value.
   bytes generation_if_equal = 2;
-  bytes value = 3 [ctype = CORD];
+
+  // Partial value.
+  // The actaual value is the catenation of all value_part fields in order.
+  bytes value_part = 3 [ctype = CORD];
 }
 
 message WriteResponse {
@@ -125,8 +141,12 @@ message WriteResponse {
 /// See tensorstore/kvstore/operations.h
 ///   kvstore::WriteOptions
 message DeleteRequest {
+  // The key to delete.
   bytes key = 1;
   KeyRange range = 2;
+
+  /// The delete is aborted if the existing generation associated with the
+  /// stored `key` does not match `if_equal`.
   bytes generation_if_equal = 3;
 }
 
diff --git a/tensorstore/kvstore/tsgrpc/kvstore_server.cc b/tensorstore/kvstore/tsgrpc/kvstore_server.cc
index ddf016901..f54ea5c58 100644
--- a/tensorstore/kvstore/tsgrpc/kvstore_server.cc
+++ b/tensorstore/kvstore/tsgrpc/kvstore_server.cc
@@ -17,6 +17,7 @@
 #include <stddef.h>
 #include <stdint.h>
 
+#include <algorithm>
 #include <atomic>
 #include <cassert>
 #include <memory>
@@ -74,7 +75,8 @@ using ::tensorstore::internal_metrics::MetricMetadata;
 using ::tensorstore::kvstore::ListEntry;
 using ::tensorstore_grpc::EncodeGenerationAndTimestamp;
 using ::tensorstore_grpc::Handler;
-using ::tensorstore_grpc::StreamHandler;
+using ::tensorstore_grpc::StreamClientRequestHandler;
+using ::tensorstore_grpc::StreamServerResponseHandler;
 using ::tensorstore_grpc::kvstore::DeleteRequest;
 using ::tensorstore_grpc::kvstore::DeleteResponse;
 using ::tensorstore_grpc::kvstore::ListRequest;
@@ -108,13 +110,16 @@ auto& list_metric = internal_metrics::Counter<int64_t>::New(
 
 ABSL_CONST_INIT internal_log::VerboseFlag verbose_logging("tsgrpc_kvstore");
 
-class ReadHandler final : public Handler<ReadRequest, ReadResponse> {
-  using Base = Handler<ReadRequest, ReadResponse>;
+constexpr size_t kMaxReadChunkSize = 1 << 20;
+
+class ReadHandler final
+    : public StreamServerResponseHandler<ReadRequest, ReadResponse> {
+  using Base = StreamServerResponseHandler<ReadRequest, ReadResponse>;
 
  public:
   ReadHandler(CallbackServerContext* grpc_context, const Request* request,
-              Response* response, KvStore kvstore)
-      : Base(grpc_context, request, response), kvstore_(std::move(kvstore)) {}
+              KvStore kvstore)
+      : Base(grpc_context, request), kvstore_(std::move(kvstore)) {}
 
   void Run() {
     ABSL_LOG_IF(INFO, verbose_logging)
@@ -142,15 +147,36 @@ class ReadHandler final : public Handler<ReadRequest, ReadResponse> {
     }
 
     internal::IntrusivePtr<ReadHandler> self{this};
-    future_ =
-        PromiseFuturePair<void>::Link(
-            [self = std::move(self)](tensorstore::Promise<void> promise,
-                                     auto read_result) {
-              if (!promise.result_needed()) return;
-              promise.SetResult(self->HandleResult(read_result.result()));
-            },
-            tensorstore::kvstore::Read(kvstore_, request()->key(), options))
-            .future;
+    future_ = tensorstore::kvstore::Read(kvstore_, request()->key(), options);
+    future_.ExecuteWhenReady(
+        [self = std::move(self)](ReadyFuture<kvstore::ReadResult> ready) {
+          self->HandleInitialResult(std::move(ready).result());
+        });
+  }
+
+  void HandleInitialResult(Result<kvstore::ReadResult> result) {
+    auto status = result.status();
+    if (!status.ok()) {
+      // Consider setting the status in the response instead.
+      Finish(status);
+      return;
+    }
+
+    auto& r = result.value();
+    response_.set_state(static_cast<ReadResponse::State>(r.state));
+    EncodeGenerationAndTimestamp(r.stamp, &response_);
+
+    value_ = std::move(r.value);
+    value_offset_ = 0;
+
+    SetNextPart();
+    StartWrite(&response_);
+  }
+
+  void SetNextPart() {
+    auto next_part = value_.Subcord(value_offset_, kMaxReadChunkSize);
+    value_offset_ = std::min(value_.size(), value_offset_ + next_part.size());
+    response_.set_value_part(std::move(next_part));
   }
 
   void OnCancel() final {
@@ -159,50 +185,75 @@ class ReadHandler final : public Handler<ReadRequest, ReadResponse> {
     Finish(::grpc::Status(::grpc::StatusCode::CANCELLED, ""));
   }
 
-  absl::Status HandleResult(const Result<kvstore::ReadResult>& result) {
-    auto status = result.status();
-    if (status.ok()) {
-      auto& r = result.value();
-      response()->set_state(static_cast<ReadResponse::State>(r.state));
-      EncodeGenerationAndTimestamp(r.stamp, response());
-      if (r.has_value()) {
-        response()->set_value(r.value);
-      }
+  void OnWriteDone(bool ok) final {
+    if (!ok) {
+      // OnDone is going to be called after we return from this method.
+      Finish(::grpc::Status(::grpc::StatusCode::UNKNOWN, "Write failed"));
+      return;
     }
-    Finish(status);
-    return status;
+    if (value_offset_ == value_.size()) {
+      Finish(::grpc::Status::OK);
+      return;
+    }
+    response_.Clear();
+    SetNextPart();
+    StartWrite(&response_);
   }
 
  private:
   KvStore kvstore_;
-  Future<void> future_;
+  Future<kvstore::ReadResult> future_;
+
+  ReadResponse response_;
+  absl::Cord value_;
+  size_t value_offset_ = 0;
 };
 
-class WriteHandler final : public Handler<WriteRequest, WriteResponse> {
-  using Base = Handler<WriteRequest, WriteResponse>;
+class WriteHandler final
+    : public StreamClientRequestHandler<WriteRequest, WriteResponse> {
+  using Base = StreamClientRequestHandler<WriteRequest, WriteResponse>;
 
  public:
-  WriteHandler(CallbackServerContext* grpc_context, const Request* request,
-               Response* response, KvStore kvstore)
-      : Base(grpc_context, request, response), kvstore_(std::move(kvstore)) {}
+  WriteHandler(CallbackServerContext* grpc_context, Response* response,
+               KvStore kvstore)
+      : Base(grpc_context, response), kvstore_(std::move(kvstore)) {}
 
-  void Run() {
-    ABSL_LOG_IF(INFO, verbose_logging)
-        << "WriteHandler " << ConciseDebugString(*request());
-    tensorstore::kvstore::WriteOptions options{};
-    options.generation_conditions.if_equal.value =
-        request()->generation_if_equal();
+  void Run() { StartRead(&request_); }
 
+  void OnReadDone(bool ok) override {
+    if (grpc_context()->IsCancelled()) {
+      // OnCancelled is going to be called and will invoke Finish, thus just
+      // stop reading sequence here.
+      return;
+    }
+    if (ok) {
+      ABSL_LOG_IF(INFO, verbose_logging)
+          << "WriteHandler " << ConciseDebugString(request_);
+      // One read chunk has completed, but not everything.
+      // According to protocol, state, generation and timestamp must be taken
+      // from the first message in the stream.
+      if (!first_request_received_) {
+        first_request_received_ = true;
+        options_.generation_conditions.if_equal.value =
+            request_.generation_if_equal();
+        key_ = request_.key();
+      }
+
+      value_.Append(request_.value_part());
+      StartRead(&request_);
+      return;
+    }
+
+    ABSL_LOG_IF(INFO, verbose_logging) << "WriteHandler starting write";
+
+    // Setup the response.
     internal::IntrusivePtr<WriteHandler> self{this};
-    future_ =
-        PromiseFuturePair<void>::Link(
-            [self = std::move(self)](Promise<void> promise, auto write_result) {
-              if (!promise.result_needed()) return;
-              promise.SetResult(self->HandleResult(write_result.result()));
-            },
-            kvstore::Write(kvstore_, request()->key(),
-                           absl::Cord(request()->value()), options))
-            .future;
+    future_ = tensorstore::kvstore::Write(kvstore_, key_, value_, options_);
+    future_.ExecuteWhenReady(
+        [self =
+             std::move(self)](ReadyFuture<TimestampedStorageGeneration> ready) {
+          self->HandleResult(std::move(ready).result());
+        });
   }
 
   void OnCancel() final {
@@ -211,19 +262,24 @@ class WriteHandler final : public Handler<WriteRequest, WriteResponse> {
     Finish(::grpc::Status(::grpc::StatusCode::CANCELLED, ""));
   }
 
-  absl::Status HandleResult(
-      const tensorstore::Result<TimestampedStorageGeneration>& result) {
+  void HandleResult(tensorstore::Result<TimestampedStorageGeneration>& result) {
     auto status = result.status();
     if (status.ok()) {
       EncodeGenerationAndTimestamp(result.value(), response());
     }
     Finish(status);
-    return status;
   }
 
  private:
   KvStore kvstore_;
-  Future<void> future_;
+  tensorstore::kvstore::WriteOptions options_;
+
+  Future<TimestampedStorageGeneration> future_;
+  WriteRequest request_;
+
+  std::string key_;
+  absl::Cord value_;
+  bool first_request_received_ = false;
 };
 
 class DeleteHandler final : public Handler<DeleteRequest, DeleteResponse> {
@@ -294,8 +350,9 @@ class DeleteHandler final : public Handler<DeleteRequest, DeleteResponse> {
   tensorstore::Future<void> future_;
 };
 
-class ListHandler final : public StreamHandler<ListRequest, ListResponse> {
-  using Base = StreamHandler<ListRequest, ListResponse>;
+class ListHandler final
+    : public StreamServerResponseHandler<ListRequest, ListResponse> {
+  using Base = StreamServerResponseHandler<ListRequest, ListResponse>;
 
  public:
   ListHandler(CallbackServerContext* grpc_context, const Request* request,
@@ -457,12 +514,12 @@ class KvStoreServer::Impl final : public KvStoreService::CallbackService {
  public:
   Impl(KvStore kvstore) : kvstore_(std::move(kvstore)) {}
 
-  ::grpc::ServerUnaryReactor* Read(::grpc::CallbackServerContext* context,
-                                   const ReadRequest* request,
-                                   ReadResponse* response) override {
+  ::grpc::ServerWriteReactor<::tensorstore_grpc::kvstore::ReadResponse>* Read(
+      ::grpc::CallbackServerContext* context,
+      const ReadRequest* request) override {
     read_metric.Increment();
     internal::IntrusivePtr<ReadHandler> handler(
-        new ReadHandler(context, request, response, kvstore_));
+        new ReadHandler(context, request, kvstore_));
     assert(handler->use_count() == 2);
     handler->Run();
     assert(handler->use_count() > 0);
@@ -470,12 +527,12 @@ class KvStoreServer::Impl final : public KvStoreService::CallbackService {
     return handler.get();
   }
 
-  ::grpc::ServerUnaryReactor* Write(::grpc::CallbackServerContext* context,
-                                    const WriteRequest* request,
-                                    WriteResponse* response) override {
+  ::grpc::ServerReadReactor<::tensorstore_grpc::kvstore::WriteRequest>* Write(
+      ::grpc::CallbackServerContext* context,
+      WriteResponse* response) override {
     write_metric.Increment();
     internal::IntrusivePtr<WriteHandler> handler(
-        new WriteHandler(context, request, response, kvstore_));
+        new WriteHandler(context, response, kvstore_));
     assert(handler->use_count() == 2);
     handler->Run();
     assert(handler->use_count() > 0);
@@ -496,7 +553,7 @@ class KvStoreServer::Impl final : public KvStoreService::CallbackService {
     return handler.get();
   }
 
-  ::grpc::ServerWriteReactor< ::tensorstore_grpc::kvstore::ListResponse>* List(
+  ::grpc::ServerWriteReactor<::tensorstore_grpc::kvstore::ListResponse>* List(
       ::grpc::CallbackServerContext* context,
       const ListRequest* request) override {
     list_metric.Increment();
diff --git a/tensorstore/kvstore/tsgrpc/kvstore_server_test.cc b/tensorstore/kvstore/tsgrpc/kvstore_server_test.cc
index ef75df93b..2acccf2cb 100644
--- a/tensorstore/kvstore/tsgrpc/kvstore_server_test.cc
+++ b/tensorstore/kvstore/tsgrpc/kvstore_server_test.cc
@@ -23,6 +23,7 @@
 #include "absl/strings/cord.h"
 #include "absl/strings/str_format.h"
 #include "absl/synchronization/notification.h"
+#include "absl/time/clock.h"
 #include <nlohmann/json.hpp>
 #include "tensorstore/context.h"
 #include "tensorstore/kvstore/key_range.h"
@@ -43,7 +44,9 @@ namespace {
 namespace kvstore = ::tensorstore::kvstore;
 using ::tensorstore::KeyRange;
 using ::tensorstore::grpc_kvstore::KvStoreServer;
+using ::tensorstore::internal::IsRegularStorageGeneration;
 using ::tensorstore::internal::MatchesKvsReadResultNotFound;
+using ::tensorstore::internal::MatchesTimestampedStorageGeneration;
 
 class KvStoreSingleton {
  public:
@@ -217,4 +220,35 @@ TEST_F(KvStoreTest, List) {
   }
 }
 
+TEST_F(KvStoreTest, MultiPartReadWrite) {
+  absl::Cord value;
+  char x = ' ';
+  while (value.size() < (2 << 20)) {
+    value.Append(std::string(1 << 12, x));
+    x++;
+    if (static_cast<int>(x) > 126) x = ' ';
+  }
+
+  auto context = tensorstore::Context::Default();
+  TENSORSTORE_ASSERT_OK_AND_ASSIGN(
+      auto store, tensorstore::kvstore::Open({{"driver", "tsgrpc_kvstore"},
+                                              {"address", address()},
+                                              {"path", "large/"}},
+                                             context)
+                      .result());
+
+  TENSORSTORE_ASSERT_OK_AND_ASSIGN(
+      auto generation, kvstore::Write(store, "large_value", value).result());
+  EXPECT_THAT(generation.generation, IsRegularStorageGeneration());
+
+  // memory kvstore driver returns the current time as the timestamp.
+  auto now = absl::Now();
+  TENSORSTORE_ASSERT_OK_AND_ASSIGN(
+      auto result, kvstore::Read(store, "large_value").result());
+
+  EXPECT_EQ(value, result.value);
+  EXPECT_THAT(result.stamp, MatchesTimestampedStorageGeneration(
+                                generation.generation, testing::Ge(now)));
+}
+
 }  // namespace
diff --git a/tensorstore/kvstore/tsgrpc/mock_kvstore_service.h b/tensorstore/kvstore/tsgrpc/mock_kvstore_service.h
index 59fd72821..6726fdd01 100644
--- a/tensorstore/kvstore/tsgrpc/mock_kvstore_service.h
+++ b/tensorstore/kvstore/tsgrpc/mock_kvstore_service.h
@@ -34,10 +34,12 @@ class MockKvStoreService : public kvstore::grpc_gen::KvStoreService::Service {
  public:
   using ServiceType = ::tensorstore_grpc::kvstore::grpc_gen::KvStoreService;
 
-  TENSORSTORE_GRPC_MOCK(Read, ::tensorstore_grpc::kvstore::ReadRequest,
-                        ::tensorstore_grpc::kvstore::ReadResponse);
-  TENSORSTORE_GRPC_MOCK(Write, ::tensorstore_grpc::kvstore::WriteRequest,
-                        ::tensorstore_grpc::kvstore::WriteResponse);
+  TENSORSTORE_GRPC_SERVER_STREAMING_MOCK(
+      Read, ::tensorstore_grpc::kvstore::ReadRequest,
+      ::tensorstore_grpc::kvstore::ReadResponse);
+  TENSORSTORE_GRPC_CLIENT_STREAMING_MOCK(
+      Write, ::tensorstore_grpc::kvstore::WriteRequest,
+      ::tensorstore_grpc::kvstore::WriteResponse);
   TENSORSTORE_GRPC_MOCK(Delete, ::tensorstore_grpc::kvstore::DeleteRequest,
                         ::tensorstore_grpc::kvstore::DeleteResponse);
   TENSORSTORE_GRPC_SERVER_STREAMING_MOCK(
diff --git a/tensorstore/kvstore/tsgrpc/tsgrpc.cc b/tensorstore/kvstore/tsgrpc/tsgrpc.cc
index 1da1c40cf..766ce8e5c 100644
--- a/tensorstore/kvstore/tsgrpc/tsgrpc.cc
+++ b/tensorstore/kvstore/tsgrpc/tsgrpc.cc
@@ -15,8 +15,10 @@
 /// \file
 /// Key-value store proxied over grpc.
 
+#include <stddef.h>
 #include <stdint.h>
 
+#include <algorithm>
 #include <atomic>
 #include <memory>
 #include <optional>
@@ -32,6 +34,7 @@
 #include "grpcpp/channel.h"  // third_party
 #include "grpcpp/client_context.h"  // third_party
 #include "grpcpp/create_channel.h"  // third_party
+#include "grpcpp/support/client_callback.h"  // third_party
 #include "grpcpp/support/status.h"  // third_party
 #include "grpcpp/support/sync_stream.h"  // third_party
 #include "tensorstore/context.h"
@@ -113,6 +116,7 @@ auto tsgrpc_metrics = []() -> TsGrpcMetrics {
 
 ABSL_CONST_INIT internal_log::VerboseFlag verbose_logging("tsgrpc_kvstore");
 
+constexpr size_t kMaxWriteChunkSize = 1 << 20;
 
 struct TsGrpcKeyValueStoreSpecData {
   std::string address;
@@ -153,6 +157,8 @@ class TsGrpcKeyValueStore
     : public internal_kvstore::RegisteredDriver<TsGrpcKeyValueStore,
                                                 TsGrpcKeyValueStoreSpec> {
  public:
+  TsGrpcKeyValueStore(const TsGrpcKeyValueStoreSpecData& spec) : spec_(spec) {}
+
   void MaybeSetDeadline(grpc::ClientContext& context) {
     if (spec_.timeout > absl::ZeroDuration() &&
         spec_.timeout != absl::InfiniteDuration()) {
@@ -182,157 +188,218 @@ class TsGrpcKeyValueStore
 
   void ListImpl(ListOptions options, ListReceiver receiver) override;
 
-  SpecData spec_;
+  TsGrpcKeyValueStoreSpecData spec_;
   std::shared_ptr<grpc::Channel> channel_;
   std::unique_ptr<KvStoreService::StubInterface> stub_;
 };
 
 ////////////////////////////////////////////////////
 
-/// Implements `TsGrpcKeyValueStore::Read`.
-struct ReadTask : public internal::AtomicReferenceCount<ReadTask> {
-  internal::IntrusivePtr<TsGrpcKeyValueStore> driver;
-  grpc::ClientContext context;
-  ReadRequest request;
-  ReadResponse response;
+// Implements TsGrpcKeyValueStore::Read
+// TODO: Add retries.
+struct ReadTask : public internal::AtomicReferenceCount<ReadTask>,
+                  public grpc::ClientReadReactor<ReadResponse> {
+  Executor executor_;
+  Promise<kvstore::ReadResult> promise_;
 
-  Future<kvstore::ReadResult> Start(kvstore::Key key,
-                                    const kvstore::ReadOptions& options) {
-    request.set_key(std::move(key));
-    request.set_generation_if_equal(
-        options.generation_conditions.if_equal.value);
-    request.set_generation_if_not_equal(
-        options.generation_conditions.if_not_equal.value);
-    if (!options.byte_range.IsFull()) {
-      request.mutable_byte_range()->set_inclusive_min(
-          options.byte_range.inclusive_min);
-      request.mutable_byte_range()->set_exclusive_max(
-          options.byte_range.exclusive_max);
-    }
-    if (options.staleness_bound != absl::InfiniteFuture()) {
-      AbslTimeToProto(options.staleness_bound,
-                      request.mutable_staleness_bound());
+  // working state.
+  grpc::ClientContext context_;
+  kvstore::ReadOptions options_;
+  ReadRequest request_;
+  ReadResponse response_;
+  kvstore::ReadResult result_;
+
+  ReadTask(Executor executor, Promise<kvstore::ReadResult> promise)
+      : executor_(std::move(executor)), promise_(std::move(promise)) {}
+
+  void TryCancel() { context_.TryCancel(); }
+
+  void Start(KvStoreService::StubInterface* stub) {
+    intrusive_ptr_increment(this);  // adopted in OnDone.
+    stub->async()->Read(&context_, &request_, this);
+
+    StartRead(&response_);
+    StartCall();
+  }
+
+  void OnReadDone(bool ok) override {
+    if (!ok) return;
+    if (!promise_.result_needed()) {
+      TryCancel();
+      return;
     }
 
-    driver->MaybeSetDeadline(context);
+    auto status = [&]() -> absl::Status {
+      if (auto status = GetMessageStatus(response_); !status.ok()) {
+        return status;
+      }
 
-    internal::IntrusivePtr<ReadTask> self(this);
-    auto pair = tensorstore::PromiseFuturePair<kvstore::ReadResult>::Make();
-    pair.promise.ExecuteWhenNotNeeded([self] { self->context.TryCancel(); });
+      if (result_.value.empty()) {
+        auto stamp = DecodeGenerationAndTimestamp(response_);
+        if (!stamp.ok()) {
+          return std::move(stamp).status();
+        }
+        result_.stamp = std::move(stamp).value();
+        result_.state =
+            static_cast<kvstore::ReadResult::State>(response_.state());
+      }
 
-    driver->stub()->async()->Read(
-        &context, &request, &response,
-        WithExecutor(driver->executor(), [self = std::move(self),
-                                          promise = std::move(pair.promise)](
-                                             ::grpc::Status s) {
-          if (!promise.result_needed()) return;
-          promise.SetResult(self->Ready(GrpcStatusToAbslStatus(s)));
-        }));
+      result_.value.Append(response_.value_part());
+      StartRead(&response_);
+      return absl::OkStatus();
+    }();
 
-    return std::move(pair.future);
+    if (!status.ok()) {
+      promise_.SetResult(std::move(status));
+      TryCancel();
+    }
   }
 
-  Result<kvstore::ReadResult> Ready(absl::Status status) {
+  void OnDone(const grpc::Status& s) override {
+    internal::IntrusivePtr<ReadTask> self(this, internal::adopt_object_ref);
+    executor_([self = std::move(self), status = s]() {
+      self->ReadFinished(GrpcStatusToAbslStatus(status));
+    });
+  }
+
+  void ReadFinished(absl::Status status) {
+    // Streaming read complete.
+    if (!promise_.result_needed()) {
+      return;
+    }
     ABSL_LOG_IF(INFO, verbose_logging)
-        << "ReadTask::Ready " << ConciseDebugString(response) << " " << status;
+        << "ReadTask::ReadFinished " << ConciseDebugString(response_) << " "
+        << status;
 
-    TENSORSTORE_RETURN_IF_ERROR(status);
-    TENSORSTORE_RETURN_IF_ERROR(GetMessageStatus(response));
-    TENSORSTORE_ASSIGN_OR_RETURN(auto stamp,
-                                 DecodeGenerationAndTimestamp(response));
-    return kvstore::ReadResult{
-        static_cast<kvstore::ReadResult::State>(response.state()),
-        absl::Cord(response.value()),
-        std::move(stamp),
-    };
+    if (!status.ok()) {
+      promise_.SetResult(status);
+    } else {
+      promise_.SetResult(std::move(result_));
+    }
   }
 };
 
-/// Implements `TsGrpcKeyValueStore::Write`.
-struct WriteTask : public internal::AtomicReferenceCount<WriteTask> {
-  internal::IntrusivePtr<TsGrpcKeyValueStore> driver;
-  grpc::ClientContext context;
-  WriteRequest request;
-  WriteResponse response;
+/// Key value store operations.
+Future<kvstore::ReadResult> TsGrpcKeyValueStore::Read(Key key,
+                                                      ReadOptions options) {
+  tsgrpc_metrics.read.Increment();
 
-  Future<TimestampedStorageGeneration> Start(
-      kvstore::Key key, const absl::Cord value,
-      const kvstore::WriteOptions& options) {
-    request.set_key(std::move(key));
-    request.set_value(value);
-    request.set_generation_if_equal(
-        options.generation_conditions.if_equal.value);
+  auto pair = PromiseFuturePair<kvstore::ReadResult>::Make();
+
+  auto task =
+      internal::MakeIntrusivePtr<ReadTask>(executor(), std::move(pair.promise));
+  MaybeSetDeadline(task->context_);
+
+  auto& request = task->request_;
+  request.set_key(std::move(key));
+  request.set_generation_if_equal(options.generation_conditions.if_equal.value);
+  request.set_generation_if_not_equal(
+      options.generation_conditions.if_not_equal.value);
+  if (!options.byte_range.IsFull()) {
+    request.mutable_byte_range()->set_inclusive_min(
+        options.byte_range.inclusive_min);
+    request.mutable_byte_range()->set_exclusive_max(
+        options.byte_range.exclusive_max);
+  }
+  if (options.staleness_bound != absl::InfiniteFuture()) {
+    AbslTimeToProto(options.staleness_bound, request.mutable_staleness_bound());
+  }
 
-    driver->MaybeSetDeadline(context);
+  task->Start(stub_.get());
+  task->promise_.ExecuteWhenNotNeeded([t = task] { t->TryCancel(); });
+  return std::move(pair.future);
+}
 
-    internal::IntrusivePtr<WriteTask> self(this);
-    auto pair =
-        tensorstore::PromiseFuturePair<TimestampedStorageGeneration>::Make();
-    pair.promise.ExecuteWhenNotNeeded([self] { self->context.TryCancel(); });
-
-    driver->stub()->async()->Write(
-        &context, &request, &response,
-        WithExecutor(driver->executor(), [self = std::move(self),
-                                          promise = std::move(pair.promise)](
-                                             ::grpc::Status s) {
-          if (!promise.result_needed()) return;
-          promise.SetResult(self->Ready(GrpcStatusToAbslStatus(s)));
-        }));
-    return std::move(pair.future);
+//////////////////////////////////////////////////////////////////////////
+
+// Implements TsGrpcKeyValueStore::Write
+// TODO: Add retries.
+struct WriteTask : public internal::AtomicReferenceCount<WriteTask>,
+                   public grpc::ClientWriteReactor<WriteRequest> {
+  Executor executor_;
+  Promise<TimestampedStorageGeneration> promise_;
+  absl::Cord value_;
+
+  // working state.
+  grpc::ClientContext context_;
+  WriteRequest request_;
+  WriteResponse response_;
+  size_t value_offset_ = 0;
+
+  WriteTask(Executor executor, Promise<TimestampedStorageGeneration> promise,
+            absl::Cord value)
+      : executor_(std::move(executor)),
+        promise_(std::move(promise)),
+        value_(std::move(value)) {}
+
+  void UpdateForNextWrite() {
+    auto next_part = value_.Subcord(value_offset_, kMaxWriteChunkSize);
+    value_offset_ = std::min(value_.size(), value_offset_ + next_part.size());
+    request_.set_value_part(std::move(next_part));
   }
 
-  Result<TimestampedStorageGeneration> Ready(absl::Status status) {
-    ABSL_LOG_IF(INFO, verbose_logging)
-        << "WriteTask::Ready " << ConciseDebugString(response) << " " << status;
-    TENSORSTORE_RETURN_IF_ERROR(status);
-    TENSORSTORE_RETURN_IF_ERROR(GetMessageStatus(response));
-    return DecodeGenerationAndTimestamp(response);
+  void TryCancel() { context_.TryCancel(); }
+
+  void Start(KvStoreService::StubInterface* stub) {
+    intrusive_ptr_increment(this);  // adopted in OnDone.
+    stub->async()->Write(&context_, &response_, this);
+
+    UpdateForNextWrite();
+
+    auto options = grpc::WriteOptions();
+    if (value_offset_ == value_.size()) {
+      options.set_last_message();
+    }
+    StartWrite(&request_, options);
+    StartCall();
   }
-};
 
-/// Implements `TsGrpcKeyValueStore::Delete`.
-struct DeleteTask : public internal::AtomicReferenceCount<DeleteTask> {
-  internal::IntrusivePtr<TsGrpcKeyValueStore> driver;
-  grpc::ClientContext context;
-  DeleteRequest request;
-  DeleteResponse response;
+  void OnWriteDone(bool ok) override {
+    // Not streaming any additional data bits.
+    if (!ok) return;
+    if (value_offset_ < value_.size()) {
+      UpdateForNextWrite();
 
-  Future<TimestampedStorageGeneration> Start(
-      kvstore::Key key, const kvstore::WriteOptions options) {
-    request.set_key(std::move(key));
-    request.set_generation_if_equal(
-        options.generation_conditions.if_equal.value);
-    return StartImpl();
+      auto options = grpc::WriteOptions();
+      if (value_offset_ == value_.size()) {
+        options.set_last_message();
+      }
+      StartWrite(&request_, options);
+    }
   }
 
-  Future<TimestampedStorageGeneration> StartRange(KeyRange range) {
-    request.mutable_range()->set_inclusive_min(range.inclusive_min);
-    request.mutable_range()->set_exclusive_max(range.exclusive_max);
-    return StartImpl();
+  void OnDone(const grpc::Status& s) override {
+    internal::IntrusivePtr<WriteTask> self(this, internal::adopt_object_ref);
+    executor_([self = std::move(self), status = s]() {
+      self->WriteFinished(GrpcStatusToAbslStatus(status));
+    });
   }
 
-  Future<TimestampedStorageGeneration> StartImpl() {
-    driver->MaybeSetDeadline(context);
+  void WriteFinished(absl::Status status) {
+    if (!promise_.result_needed()) {
+      return;
+    }
+    ABSL_LOG_IF(INFO, verbose_logging)
+        << "WriteTask::WriteFinished " << ConciseDebugString(response_) << " "
+        << status;
 
-    internal::IntrusivePtr<DeleteTask> self(this);
-    auto pair =
-        tensorstore::PromiseFuturePair<TimestampedStorageGeneration>::Make();
-    pair.promise.ExecuteWhenNotNeeded([self] { self->context.TryCancel(); });
-
-    driver->stub()->async()->Delete(
-        &context, &request, &response,
-        WithExecutor(driver->executor(), [self = std::move(self),
-                                          promise = std::move(pair.promise)](
-                                             ::grpc::Status s) {
-          if (!promise.result_needed()) return;
-          promise.SetResult(self->Ready(GrpcStatusToAbslStatus(s)));
-        }));
-    return std::move(pair.future);
+    promise_.SetResult([&]() -> Result<TimestampedStorageGeneration> {
+      TENSORSTORE_RETURN_IF_ERROR(status);
+      TENSORSTORE_RETURN_IF_ERROR(GetMessageStatus(response_));
+      return DecodeGenerationAndTimestamp(response_);
+    }());
   }
+};
+
+//////////////////////////////////////////////////////////////////////////
+
+struct DeleteCallbackState {
+  grpc::ClientContext context;
+  DeleteResponse response;
 
   Result<TimestampedStorageGeneration> Ready(absl::Status status) {
     ABSL_LOG_IF(INFO, verbose_logging)
-        << "DeleteTask::Ready " << ConciseDebugString(response) << " "
+        << "DeleteCallbackState " << ConciseDebugString(response) << " "
         << status;
     TENSORSTORE_RETURN_IF_ERROR(status);
     TENSORSTORE_RETURN_IF_ERROR(GetMessageStatus(response));
@@ -340,6 +407,82 @@ struct DeleteTask : public internal::AtomicReferenceCount<DeleteTask> {
   }
 };
 
+Future<TimestampedStorageGeneration> TsGrpcKeyValueStore::Write(
+    Key key, std::optional<Value> value, WriteOptions options) {
+  auto pair = PromiseFuturePair<TimestampedStorageGeneration>::Make();
+
+  if (!value) {
+    // empty value is delete.
+    tsgrpc_metrics.delete_calls.Increment();
+
+    DeleteRequest request;
+    request.set_key(std::move(key));
+    request.set_generation_if_equal(
+        options.generation_conditions.if_equal.value);
+
+    auto callback = std::make_shared<DeleteCallbackState>();
+    MaybeSetDeadline(callback->context);
+    pair.promise.ExecuteWhenNotNeeded(
+        [callback] { callback->context.TryCancel(); });
+
+    auto* callback_ptr = callback.get();
+    stub()->async()->Delete(
+        &callback_ptr->context, &request, &callback_ptr->response,
+        WithExecutor(
+            executor(), [callback = std::move(callback),
+                         promise = std::move(pair.promise)](::grpc::Status s) {
+              if (!promise.result_needed()) return;
+              promise.SetResult(callback->Ready(GrpcStatusToAbslStatus(s)));
+            }));
+    return std::move(pair.future);
+  }
+
+  tsgrpc_metrics.write.Increment();
+
+  auto state = internal::MakeIntrusivePtr<WriteTask>(
+      executor(), std::move(pair.promise), *std::move(value));
+  MaybeSetDeadline(state->context_);
+
+  auto& request = state->request_;
+  request.set_key(std::move(key));
+  request.set_generation_if_equal(options.generation_conditions.if_equal.value);
+
+  state->Start(stub_.get());
+  state->promise_.ExecuteWhenNotNeeded([state] { state->TryCancel(); });
+  return std::move(pair.future);
+}
+
+Future<const void> TsGrpcKeyValueStore::DeleteRange(KeyRange range) {
+  if (range.empty()) return absl::OkStatus();
+  tsgrpc_metrics.delete_range.Increment();
+
+  DeleteRequest request;
+  request.mutable_range()->set_inclusive_min(range.inclusive_min);
+  request.mutable_range()->set_exclusive_max(range.exclusive_max);
+
+  auto callback = std::make_shared<DeleteCallbackState>();
+  MaybeSetDeadline(callback->context);
+
+  auto pair = PromiseFuturePair<void>::Make(absl::OkStatus());
+  pair.promise.ExecuteWhenNotNeeded(
+      [callback] { callback->context.TryCancel(); });
+
+  auto* callback_ptr = callback.get();
+  stub()->async()->Delete(
+      &callback_ptr->context, &request, &callback_ptr->response,
+      WithExecutor(
+          executor(), [callback = std::move(callback),
+                       promise = std::move(pair.promise)](::grpc::Status s) {
+            if (!promise.result_needed()) return;
+            if (auto result = callback->Ready(GrpcStatusToAbslStatus(s));
+                !result.ok()) {
+              promise.SetResult(std::move(result).status());
+            }
+          }));
+
+  return std::move(pair.future);
+}
+
 // Implements TsGrpcKeyValueStore::List
 // NOTE: Convert to async().
 struct ListTask {
@@ -399,46 +542,6 @@ struct ListTask {
   }
 };
 
-/// Key value store operations.
-Future<kvstore::ReadResult> TsGrpcKeyValueStore::Read(Key key,
-                                                      ReadOptions options) {
-  tsgrpc_metrics.read.Increment();
-  auto task = internal::MakeIntrusivePtr<ReadTask>();
-  task->driver = internal::IntrusivePtr<TsGrpcKeyValueStore>(this);
-  return task->Start(std::move(key), options);
-}
-
-Future<TimestampedStorageGeneration> TsGrpcKeyValueStore::Write(
-    Key key, std::optional<Value> value, WriteOptions options) {
-  if (value) {
-    tsgrpc_metrics.write.Increment();
-    auto task = internal::MakeIntrusivePtr<WriteTask>();
-    task->driver = internal::IntrusivePtr<TsGrpcKeyValueStore>(this);
-    return task->Start(std::move(key), value.value(), options);
-  } else {
-    // empty value is delete.
-    tsgrpc_metrics.delete_calls.Increment();
-    auto task = internal::MakeIntrusivePtr<DeleteTask>();
-    task->driver = internal::IntrusivePtr<TsGrpcKeyValueStore>(this);
-    return task->Start(std::move(key), options);
-  }
-}
-
-Future<const void> TsGrpcKeyValueStore::DeleteRange(KeyRange range) {
-  if (range.empty()) return absl::OkStatus();
-  tsgrpc_metrics.delete_range.Increment();
-  auto task = internal::MakeIntrusivePtr<DeleteTask>();
-  task->driver = internal::IntrusivePtr<TsGrpcKeyValueStore>(this);
-
-  // Convert Future<TimestampedStorageGeneration> to Future<void>
-  return MapFuture(
-      InlineExecutor{},
-      [](const Result<TimestampedStorageGeneration>& result) {
-        return MakeResult(result.status());
-      },
-      task->StartRange(std::move(range)));
-}
-
 void TsGrpcKeyValueStore::ListImpl(ListOptions options, ListReceiver receiver) {
   if (options.range.empty()) {
     execution::set_starting(receiver, [] {});
@@ -461,15 +564,15 @@ void TsGrpcKeyValueStore::ListImpl(ListOptions options, ListReceiver receiver) {
 }
 
 Future<kvstore::DriverPtr> TsGrpcKeyValueStoreSpec::DoOpen() const {
-  auto driver = internal::MakeIntrusivePtr<TsGrpcKeyValueStore>();
-  driver->spec_ = data_;
+  auto driver = internal::MakeIntrusivePtr<TsGrpcKeyValueStore>(data_);
 
   // Create a communication channel with credentials, then use that
   // to construct a gprc stub.
   //
   // TODO: Determine a better mapping to a grpc credentials for this.
-  // grpc::Credentials ties the authentication to the communication channel
-  // See: <grpcpp/security/credentials.h>, https://grpc.io/docs/guides/auth/
+  // grpc::Credentials ties the authentication to the communication
+  // channel See: <grpcpp/security/credentials.h>,
+  // https://grpc.io/docs/guides/auth/
   ABSL_LOG_IF(INFO, verbose_logging)
       << "tsgrpc_kvstore address=" << data_.address;
 
diff --git a/tensorstore/kvstore/tsgrpc/tsgrpc_test.cc b/tensorstore/kvstore/tsgrpc/tsgrpc_test.cc
index 8454eafcd..63cd3098a 100644
--- a/tensorstore/kvstore/tsgrpc/tsgrpc_test.cc
+++ b/tensorstore/kvstore/tsgrpc/tsgrpc_test.cc
@@ -12,6 +12,8 @@
 // See the License for the specific language governing permissions and
 // limitations under the License.
 
+#include <stddef.h>
+
 #include <optional>
 #include <string>
 #include <vector>
@@ -97,7 +99,7 @@ TEST_F(TsGrpcMockTest, Read) {
 
   ReadResponse response = ParseTextProtoOrDie(R"pb(
     state: 2
-    value: '1234'
+    value_part: '1234'
     generation_and_timestamp {
       generation: '1\001'
       timestamp { seconds: 1634327736 nanos: 123456 }
@@ -105,7 +107,12 @@ TEST_F(TsGrpcMockTest, Read) {
   )pb");
 
   EXPECT_CALL(mock(), Read(_, EqualsProto(expected_request), _))
-      .WillOnce(DoAll(SetArgPointee<2>(response), Return(grpc::Status::OK)));
+      .WillOnce(testing::Invoke(
+          [=](auto*, auto*,
+              grpc::ServerWriter<ReadResponse>* resp) -> ::grpc::Status {
+            resp->Write(response);
+            return grpc::Status::OK;
+          }));
 
   kvstore::ReadResult result;
   {
@@ -150,10 +157,57 @@ TEST_F(TsGrpcMockTest, ReadWithOptions) {
   EXPECT_EQ(result.stamp.generation, StorageGeneration::Unknown());
 }
 
+TEST_F(TsGrpcMockTest, ReadMultipart) {
+  ReadRequest expected_request = ParseTextProtoOrDie(R"pb(
+    key: 'abc'
+  )pb");
+
+  std::vector<ReadResponse> responses{
+      ParseTextProtoOrDie(R"pb(
+        state: 2
+        value_part: '1234'
+        generation_and_timestamp {
+          generation: '1\001'
+          timestamp { seconds: 1634327736 nanos: 123456 }
+        }
+      )pb"),
+      ParseTextProtoOrDie(R"pb(
+        value_part: '5678'
+      )pb"),
+      ParseTextProtoOrDie(R"pb(
+        value_part: '9012'
+      )pb"),
+  };
+
+  EXPECT_CALL(mock(), Read(_, EqualsProto(expected_request), _))
+      .WillOnce(testing::Invoke(
+          [=](auto*, auto*,
+              grpc::ServerWriter<ReadResponse>* resp) -> ::grpc::Status {
+            for (const auto& response : responses) {
+              resp->Write(response);
+            }
+            return grpc::Status::OK;
+          }));
+
+  kvstore::ReadResult result;
+  {
+    auto store = OpenStore();
+    TENSORSTORE_ASSERT_OK_AND_ASSIGN(
+        result, kvstore::Read(store, expected_request.key()).result());
+  }
+
+  // Individual result field verification.
+  EXPECT_TRUE(result.has_value());
+  EXPECT_EQ(result.value, "123456789012");
+  EXPECT_EQ(result.stamp.time,
+            absl::FromUnixSeconds(1634327736) + absl::Nanoseconds(123456));
+  EXPECT_EQ(result.stamp.generation, StorageGeneration::FromString("1"));
+}
+
 TEST_F(TsGrpcMockTest, Write) {
   WriteRequest expected_request = ParseTextProtoOrDie(R"pb(
     key: 'abc'
-    value: '1234'
+    value_part: '1234'
   )pb");
 
   WriteResponse response = ParseTextProtoOrDie(R"pb(
@@ -163,15 +217,24 @@ TEST_F(TsGrpcMockTest, Write) {
     }
   )pb");
 
-  EXPECT_CALL(mock(), Write(_, EqualsProto(expected_request), _))
-      .WillOnce(DoAll(SetArgPointee<2>(response), Return(grpc::Status::OK)));
+  EXPECT_CALL(mock(), Write(_, _, _))
+      .WillOnce(
+          testing::Invoke([=](auto*, grpc::ServerReader<WriteRequest>* req,
+                              WriteResponse* resp) -> ::grpc::Status {
+            WriteRequest actual_request;
+            EXPECT_TRUE(req->Read(&actual_request));
+            EXPECT_THAT(actual_request, EqualsProto(expected_request));
+            EXPECT_FALSE(req->Read(&actual_request));
+            *resp = response;
+            return grpc::Status::OK;
+          }));
 
   tensorstore::TimestampedStorageGeneration result;
   {
     auto store = OpenStore();
     TENSORSTORE_ASSERT_OK_AND_ASSIGN(
         result, kvstore::Write(store, expected_request.key(),
-                               absl::Cord(expected_request.value()))
+                               absl::Cord(expected_request.value_part()))
                     .result());
   }
   EXPECT_EQ(result.generation, StorageGeneration::FromString("1"));
@@ -190,8 +253,17 @@ TEST_F(TsGrpcMockTest, WriteEmpty) {
     }
   )pb");
 
-  EXPECT_CALL(mock(), Write(_, EqualsProto(expected_request), _))
-      .WillOnce(DoAll(SetArgPointee<2>(response), Return(grpc::Status::OK)));
+  EXPECT_CALL(mock(), Write(_, _, _))
+      .WillOnce(
+          testing::Invoke([=](auto*, grpc::ServerReader<WriteRequest>* req,
+                              WriteResponse* resp) -> ::grpc::Status {
+            WriteRequest actual_request;
+            EXPECT_TRUE(req->Read(&actual_request));
+            EXPECT_THAT(actual_request, EqualsProto(expected_request));
+            EXPECT_FALSE(req->Read(&actual_request));
+            *resp = response;
+            return grpc::Status::OK;
+          }));
 
   tensorstore::TimestampedStorageGeneration result;
   {
@@ -207,7 +279,7 @@ TEST_F(TsGrpcMockTest, WriteEmpty) {
 TEST_F(TsGrpcMockTest, WriteWithOptions) {
   WriteRequest expected_request = ParseTextProtoOrDie(R"pb(
     key: 'abc'
-    value: '1234'
+    value_part: '1234'
     generation_if_equal: "abc\001"
   )pb");
 
@@ -218,15 +290,24 @@ TEST_F(TsGrpcMockTest, WriteWithOptions) {
     }
   )pb");
 
-  EXPECT_CALL(mock(), Write(_, EqualsProto(expected_request), _))
-      .WillOnce(DoAll(SetArgPointee<2>(response), Return(grpc::Status::OK)));
+  EXPECT_CALL(mock(), Write(_, _, _))
+      .WillOnce(
+          testing::Invoke([=](auto*, grpc::ServerReader<WriteRequest>* req,
+                              WriteResponse* resp) -> ::grpc::Status {
+            WriteRequest actual_request;
+            EXPECT_TRUE(req->Read(&actual_request));
+            EXPECT_THAT(actual_request, EqualsProto(expected_request));
+            EXPECT_FALSE(req->Read(&actual_request));
+            *resp = response;
+            return grpc::Status::OK;
+          }));
 
   tensorstore::TimestampedStorageGeneration result;
   {
     auto store = OpenStore();
     TENSORSTORE_ASSERT_OK_AND_ASSIGN(
         result, kvstore::Write(store, expected_request.key(),
-                               absl::Cord(expected_request.value()),
+                               absl::Cord(expected_request.value_part()),
                                {StorageGeneration::FromString("abc")})
                     .result());
   }
@@ -260,6 +341,45 @@ TEST_F(TsGrpcMockTest, WriteNullopt) {
   EXPECT_EQ(result.generation, StorageGeneration::FromString("1"));
 }
 
+TEST_F(TsGrpcMockTest, WriteMultipart) {
+  absl::Cord value;
+  char x = ' ';
+  while (value.size() < (2 << 20)) {
+    value.Append(std::string(1 << 12, x));
+    x++;
+    if (static_cast<int>(x) > 126) x = ' ';
+  };
+
+  WriteResponse response = ParseTextProtoOrDie(R"pb(
+    generation_and_timestamp {
+      generation: '1\001'
+      timestamp { seconds: 1634327736 nanos: 123456 }
+    }
+  )pb");
+
+  EXPECT_CALL(mock(), Write(_, _, _))
+      .WillOnce(
+          testing::Invoke([=](auto*, grpc::ServerReader<WriteRequest>* req,
+                              WriteResponse* resp) -> ::grpc::Status {
+            WriteRequest actual_request;
+            size_t i = 0;
+            while (req->Read(&actual_request)) {
+              i++;
+            }
+            EXPECT_EQ(i, 2);
+            *resp = response;
+            return grpc::Status::OK;
+          }));
+
+  tensorstore::TimestampedStorageGeneration result;
+  {
+    auto store = OpenStore();
+    TENSORSTORE_ASSERT_OK_AND_ASSIGN(
+        result, kvstore::Write(store, "large_value", value).result());
+  }
+  EXPECT_EQ(result.generation, StorageGeneration::FromString("1"));
+}
+
 TEST_F(TsGrpcMockTest, Delete) {
   DeleteRequest expected_request = ParseTextProtoOrDie(R"pb(
     key: 'abc'