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Various problems can cause sex determination to be inconclusive (intermediate read dosage):
check library-level bams, to exclude bioinfo issues with accidentally merging libraries from distinct individuals
filter reads with low MAPQ (e.g. < 30)
ensure mito reads are excluded - some samples can have high MT/nuc ratio and if there is no mito sequence in the reference, the mito reads can map to NUMTs instead
The text was updated successfully, but these errors were encountered:
Various problems can cause sex determination to be inconclusive (intermediate read dosage):
The text was updated successfully, but these errors were encountered: