diff --git a/scripts/run-tests.sh b/scripts/run-tests.sh
index d3dd7f27..e1fa671d 100755
--- a/scripts/run-tests.sh
+++ b/scripts/run-tests.sh
@@ -26,6 +26,23 @@ while (( "$#" )); do
   esac
 done
 
+supports_flavor() {
+  local fixture="$1"
+  local flavor="$2"
+
+  if [[ "$flavor" == "jsi" ]]; then
+    return 0
+  fi
+
+  local flavor_file="${fixture}/tests/bindings/.supported-flavors.txt"
+  if [[ -f "$flavor_file" ]]; then
+    if grep -q "$flavor" "$flavor_file"; then
+      return 0
+    fi
+  fi
+
+  return 1
+}
 
 for test in "${root}"/typescript/tests/*.test.ts ; do
     echo "Running test $test"
@@ -43,13 +60,21 @@ for fixture in ${fixtures} ; do
     if [[ " ${excluded_fixtures[@]} " =~ " ${fixture} " ]]; then
         continue
     fi
-    echo "Running fixture ${fixture}"
+
     # This should all go in either an xtask or into our uniffi-bindgen command.
     # This builds the crate into the target dir.
     fixture_dir="${root}/fixtures/${fixture}"
+
+    if ! supports_flavor "${fixture_dir}" "${flavor}"; then
+      echo "Skipping fixture ${fixture}"
+      continue
+    fi
+
     test_file="${fixture_dir}/tests/bindings/test_${fixture//-/_}.ts"
     config_file="${fixture_dir}/uniffi.toml"
     out_dir="${fixture_dir}/generated"
+
+    echo "Running fixture ${fixture}"
     rm -Rf "${out_dir}" 2>/dev/null
 
     cpp_dir="${out_dir}/cpp"