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Add feature for calculating "connectivity" score of a gene set #120

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ChristopherMancuso opened this issue Apr 8, 2022 · 0 comments
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enhancement New feature or request

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@ChristopherMancuso
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In the web server paper review and from talking to other people, I have heard people would like more guidance on which network to choose. Since the performance of the method is strongly based on the connectivity of the gene set in the network, it would be good to return that score as well. This will be a v2 enhancement as we need to consider

  • What does a score like this mean if Embedding or Influence is chosen?
  • How much computational time and resources does this take? Can we do for all the networks up front before the user choses? This point is mostly a consideration for eventually doing this through the web server
  • How to make a single score returned to a user interpretable? Have to do this on a number of background sets and return as z-score?
@ChristopherMancuso ChristopherMancuso added the enhancement New feature or request label Apr 8, 2022
@ChristopherMancuso ChristopherMancuso self-assigned this Sep 26, 2024
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