diff --git a/itest/lnd_channel_balance_test.go b/itest/lnd_channel_balance_test.go
index 72dd16ea34..8ab276d2e6 100644
--- a/itest/lnd_channel_balance_test.go
+++ b/itest/lnd_channel_balance_test.go
@@ -156,7 +156,7 @@ func testChannelUnsettledBalance(ht *lntest.HarnessTest) {
 				TimeoutSeconds: 60,
 				FeeLimitMsat:   noFeeLimitMsat,
 			}
-			alice.RPC.SendPayment(req)
+			ht.SendPaymentAssertInflight(alice, req)
 		}()
 	}
 
diff --git a/itest/lnd_channel_force_close_test.go b/itest/lnd_channel_force_close_test.go
index 33311922b0..e5ef6b7cab 100644
--- a/itest/lnd_channel_force_close_test.go
+++ b/itest/lnd_channel_force_close_test.go
@@ -114,7 +114,7 @@ func runChannelForceClosureTest(ht *lntest.HarnessTest,
 			TimeoutSeconds: 60,
 			FeeLimitMsat:   noFeeLimitMsat,
 		}
-		alice.RPC.SendPayment(req)
+		ht.SendPaymentAssertInflight(alice, req)
 	}
 
 	// Once the HTLC has cleared, all the nodes n our mini network should
diff --git a/itest/lnd_forward_interceptor_test.go b/itest/lnd_forward_interceptor_test.go
index 0edf1e1098..a58dc34154 100644
--- a/itest/lnd_forward_interceptor_test.go
+++ b/itest/lnd_forward_interceptor_test.go
@@ -508,8 +508,7 @@ func testForwardInterceptorWireRecords(ht *lntest.HarnessTest) {
 		FeeLimitMsat:          noFeeLimitMsat,
 		FirstHopCustomRecords: customRecords,
 	}
-
-	_ = alice.RPC.SendPayment(sendReq)
+	ht.SendPaymentAssertInflight(alice, sendReq)
 
 	// We start the htlc interceptor with a simple implementation that saves
 	// all intercepted packets. These packets are held to simulate a
@@ -635,8 +634,7 @@ func testForwardInterceptorRestart(ht *lntest.HarnessTest) {
 		FeeLimitMsat:          noFeeLimitMsat,
 		FirstHopCustomRecords: customRecords,
 	}
-
-	_ = alice.RPC.SendPayment(sendReq)
+	ht.SendPaymentAssertInflight(alice, sendReq)
 
 	// We start the htlc interceptor with a simple implementation that saves
 	// all intercepted packets. These packets are held to simulate a
diff --git a/itest/lnd_hold_invoice_force_test.go b/itest/lnd_hold_invoice_force_test.go
index 7c616e7a50..8cdd8a5298 100644
--- a/itest/lnd_hold_invoice_force_test.go
+++ b/itest/lnd_hold_invoice_force_test.go
@@ -44,7 +44,7 @@ func testHoldInvoiceForceClose(ht *lntest.HarnessTest) {
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	ht.AssertInvoiceState(stream, lnrpc.Invoice_ACCEPTED)
 
diff --git a/itest/lnd_htlc_timeout_resolver_test.go b/itest/lnd_htlc_timeout_resolver_test.go
index 71a44966ed..cd1dd3d483 100644
--- a/itest/lnd_htlc_timeout_resolver_test.go
+++ b/itest/lnd_htlc_timeout_resolver_test.go
@@ -131,7 +131,7 @@ func testHtlcTimeoutResolverExtractPreimageRemote(ht *lntest.HarnessTest) {
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// Once the payment sent, Alice should have one outgoing HTLC active.
 	ht.AssertOutgoingHTLCActive(alice, aliceChanPoint, payHash[:])
@@ -270,7 +270,7 @@ func testHtlcTimeoutResolverExtractPreimageLocal(ht *lntest.HarnessTest) {
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// Once the payment sent, Alice should have one outgoing HTLC active.
 	ht.AssertOutgoingHTLCActive(alice, aliceChanPoint, payHash[:])
diff --git a/itest/lnd_misc_test.go b/itest/lnd_misc_test.go
index 02e3386e6a..33a7067552 100644
--- a/itest/lnd_misc_test.go
+++ b/itest/lnd_misc_test.go
@@ -632,8 +632,10 @@ func testRejectHTLC(ht *lntest.HarnessTest) {
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	payStream := alice.RPC.SendPayment(paymentReq)
-	ht.AssertPaymentStatusFromStream(payStream, lnrpc.Payment_FAILED)
+	ht.SendPaymentAssertFail(
+		alice, paymentReq,
+		lnrpc.PaymentFailureReason_FAILURE_REASON_NO_ROUTE,
+	)
 
 	ht.AssertLastHTLCError(alice, lnrpc.Failure_CHANNEL_DISABLED)
 
diff --git a/itest/lnd_multi-hop_force_close_test.go b/itest/lnd_multi-hop_force_close_test.go
index 46631bbda9..99705ff44c 100644
--- a/itest/lnd_multi-hop_force_close_test.go
+++ b/itest/lnd_multi-hop_force_close_test.go
@@ -306,7 +306,7 @@ func runLocalClaimOutgoingHTLC(ht *lntest.HarnessTest,
 		routeHints = makeRouteHints(bob, carol, params.ZeroConf)
 	}
 
-	alice.RPC.SendPayment(&routerrpc.SendPaymentRequest{
+	req := &routerrpc.SendPaymentRequest{
 		Dest:           carolPubKey,
 		Amt:            int64(dustHtlcAmt),
 		PaymentHash:    dustPayHash,
@@ -314,9 +314,10 @@ func runLocalClaimOutgoingHTLC(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 		RouteHints:     routeHints,
-	})
+	}
+	ht.SendPaymentAssertInflight(alice, req)
 
-	alice.RPC.SendPayment(&routerrpc.SendPaymentRequest{
+	req = &routerrpc.SendPaymentRequest{
 		Dest:           carolPubKey,
 		Amt:            int64(htlcAmt),
 		PaymentHash:    payHash,
@@ -324,7 +325,8 @@ func runLocalClaimOutgoingHTLC(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 		RouteHints:     routeHints,
-	})
+	}
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// Verify that all nodes in the path now have two HTLC's with the
 	// proper parameters.
@@ -653,7 +655,7 @@ func runMultiHopReceiverPreimageClaim(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// At this point, all 3 nodes should now have an active channel with
 	// the created HTLC pending on all of them.
@@ -1014,7 +1016,7 @@ func runLocalForceCloseBeforeHtlcTimeout(ht *lntest.HarnessTest,
 		FeeLimitMsat:   noFeeLimitMsat,
 		RouteHints:     routeHints,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// Once the HTLC has cleared, all channels in our mini network should
 	// have the it locked in.
@@ -1343,7 +1345,7 @@ func runRemoteForceCloseBeforeHtlcTimeout(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// Once the HTLC has cleared, all the nodes in our mini network should
 	// show that the HTLC has been locked in.
@@ -1602,7 +1604,7 @@ func runLocalClaimIncomingHTLC(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// At this point, all 3 nodes should now have an active channel with
 	// the created HTLC pending on all of them.
@@ -1913,7 +1915,7 @@ func runLocalClaimIncomingHTLCLeased(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// At this point, all 3 nodes should now have an active channel with
 	// the created HTLC pending on all of them.
@@ -2268,7 +2270,7 @@ func runLocalPreimageClaim(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// At this point, all 3 nodes should now have an active channel with
 	// the created HTLC pending on all of them.
@@ -2551,7 +2553,7 @@ func runLocalPreimageClaimLeased(ht *lntest.HarnessTest,
 		TimeoutSeconds: 60,
 		FeeLimitMsat:   noFeeLimitMsat,
 	}
-	alice.RPC.SendPayment(req)
+	ht.SendPaymentAssertInflight(alice, req)
 
 	// At this point, all 3 nodes should now have an active channel with
 	// the created HTLC pending on all of them.
@@ -2998,7 +3000,7 @@ func runHtlcAggregation(ht *lntest.HarnessTest,
 			TimeoutSeconds: 60,
 			FeeLimitMsat:   noFeeLimitMsat,
 		}
-		alice.RPC.SendPayment(req)
+		ht.SendPaymentAssertInflight(alice, req)
 	}
 
 	// And Carol will pay Alice's.
@@ -3008,7 +3010,7 @@ func runHtlcAggregation(ht *lntest.HarnessTest,
 			TimeoutSeconds: 60,
 			FeeLimitMsat:   noFeeLimitMsat,
 		}
-		carol.RPC.SendPayment(req)
+		ht.SendPaymentAssertInflight(carol, req)
 	}
 
 	// At this point, all 3 nodes should now the HTLCs active on their
diff --git a/itest/lnd_watchtower_test.go b/itest/lnd_watchtower_test.go
index 80a0eae5a3..a68df852bc 100644
--- a/itest/lnd_watchtower_test.go
+++ b/itest/lnd_watchtower_test.go
@@ -655,17 +655,12 @@ func generateBackups(ht *lntest.HarnessTest, srcNode,
 	)
 
 	send := func(node *node.HarnessNode, payReq string) {
-		stream := node.RPC.SendPayment(
-			&routerrpc.SendPaymentRequest{
-				PaymentRequest: payReq,
-				TimeoutSeconds: 60,
-				FeeLimitMsat:   noFeeLimitMsat,
-			},
-		)
-
-		ht.AssertPaymentStatusFromStream(
-			stream, lnrpc.Payment_SUCCEEDED,
-		)
+		req := &routerrpc.SendPaymentRequest{
+			PaymentRequest: payReq,
+			TimeoutSeconds: 60,
+			FeeLimitMsat:   noFeeLimitMsat,
+		}
+		ht.SendPaymentAssertSettled(node, req)
 	}
 
 	// Pay each invoice.