diff --git a/Project.toml b/Project.toml
index 10a8695..7b74ebb 100644
--- a/Project.toml
+++ b/Project.toml
@@ -1,7 +1,7 @@
 name = "AxisKeys"
 uuid = "94b1ba4f-4ee9-5380-92f1-94cde586c3c5"
 license = "MIT"
-version = "0.2.7"
+version = "0.2.8"
 
 [deps]
 AbstractFFTs = "621f4979-c628-5d54-868e-fcf4e3e8185c"
@@ -23,6 +23,7 @@ BenchmarkTools = "0.5, 1.0"
 ChainRulesCore = "1"
 ChainRulesTestUtils = "1"
 CovarianceEstimation = "0.2"
+DataFrames = "1"
 FiniteDifferences = "0.12"
 IntervalSets = "0.5.1, 0.6, 0.7"
 InvertedIndices = "1.0"
@@ -36,6 +37,7 @@ julia = "1.6"
 [extras]
 BenchmarkTools = "6e4b80f9-dd63-53aa-95a3-0cdb28fa8baf"
 ChainRulesTestUtils = "cdddcdb0-9152-4a09-a978-84456f9df70a"
+DataFrames = "a93c6f00-e57d-5684-b7b6-d8193f3e46c0"
 Dates = "ade2ca70-3891-5945-98fb-dc099432e06a"
 FFTW = "7a1cc6ca-52ef-59f5-83cd-3a7055c09341"
 FiniteDifferences = "26cc04aa-876d-5657-8c51-4c34ba976000"
@@ -45,4 +47,4 @@ UniqueVectors = "2fbcfb34-fd0c-5fbb-b5d7-e826d8f5b0a9"
 Unitful = "1986cc42-f94f-5a68-af5c-568840ba703d"
 
 [targets]
-test = ["BenchmarkTools", "ChainRulesTestUtils", "Dates", "FiniteDifferences", "FFTW", "NamedArrays", "Test", "UniqueVectors", "Unitful"]
+test = ["BenchmarkTools", "ChainRulesTestUtils", "DataFrames", "Dates", "FiniteDifferences", "FFTW", "NamedArrays", "Test", "UniqueVectors", "Unitful"]
diff --git a/src/tables.jl b/src/tables.jl
index 6e60d84..526d833 100644
--- a/src/tables.jl
+++ b/src/tables.jl
@@ -138,22 +138,30 @@ function populate!(A, table, value::Symbol; force=false)
     # Use a BitArray mask to detect duplicates and error instead of overwriting.
     mask = force ? falses() : falses(size(A))
 
-    for r in Tables.rows(table)
-        vals = Tuple(Tables.getcolumn(r, c) for c in dimnames(A))
-        inds = map(findindex, vals, axiskeys(A))
+    cols = Tables.columns(table)
+    value_column = Tables.getcolumn(cols, value)
+    axis_key_columns = Tuple(Tables.getcolumn(cols, c) for c in dimnames(A))
+    return populate_function_barrier!(A, value_column, axis_key_columns, mask, force)
+end
+
+# eltypes of value and axis_key_columns aren't inferable in `populate!` if the `table`
+# doesn't have typed columns, as is the case for DataFrames. By passing them into
+# `populate_function_barrier!` once they've been pulled out of a DataFrame ensures
+# inference is possible for the loop.
+function populate_function_barrier!(A, value_column, axis_key_columns, mask, force)
+    for (val, keys...) in zip(value_column, axis_key_columns...)
+        inds = map(AxisKeys.findindex, keys, axiskeys(A))
 
         # Handle duplicate error checking if applicable
         if !force
             # Error if mask already set.
-            mask[inds...] && throw(ArgumentError("Key $vals is not unique"))
+            mask[inds...] && throw(ArgumentError("Key $keys is not unique"))
             # Set mask, marking that we've set this index
             setindex!(mask, true, inds...)
         end
 
-        # Insert our value into the data array
-        setindex!(A, Tables.getcolumn(r, value), inds...)
+        setindex!(A, val, inds...)
     end
-
     return A
 end
 
diff --git a/test/_packages.jl b/test/_packages.jl
index 1f32f9e..50facda 100644
--- a/test/_packages.jl
+++ b/test/_packages.jl
@@ -1,5 +1,10 @@
 using Test, AxisKeys
 
+function count_allocs(f, args...)
+    stats = @timed f(args...)
+    return Base.gc_alloc_count(stats.gcstats)
+end
+
 @testset "offset" begin
     using OffsetArrays
 
@@ -38,6 +43,14 @@ end
         @test dimnames(k) == (:aa,)
     end
 end
+@testset "DataFrames" begin
+    using DataFrames: DataFrame
+
+    X = KeyedArray(randn(1000, 1500), a=1:1000, b=1:1500)
+    df = DataFrame(X)
+    wrapdims(df, :value, :a, :b) # compile
+    @test count_allocs(wrapdims, df, :value, :a, :b) < 1_000
+end
 @testset "tables" begin
     using Tables