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meren committed Oct 15, 2023
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Expand Up @@ -253,7 +253,7 @@ molecular ‘omics’ for microbial community profiling](https://www.nature.com/
* *Discussion Leaders*:

* Iva
* Meren
* Jessika

* *Learning Objectives*:

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* Schwarz MY, et al (2018). [Microbiome characterization by high-throughput transfer RNA sequencing and modification analysis](https://www.nature.com/articles/s41467-018-07675-z). *Nature Communications*.
* Orellana EA, et al (2022). [tRNA dysregulation and disease](https://doi.org/10.1038/s41576-022-00501-9). *Nature Reviews Genetics*.

### 22/01/24 :: **Metabolomics**: making sense of the chemical currencies of life
### 22/01/24 :: Linking **metabolomics and (meta)genomics**: opportunities and limitations

* *Discussion Leaders*:

* Jessika
* Meren

* *Learning Objectives*:

* TBD
* Recognizing how measurements of metabolites from the environment are linked to metabolic pathways in genomes
* Understanding the limitations of combining metagenomics and metabolomics in simple and complex environments
* Identifying the limitations of metagenomics to gain insights into the chemical currencies of life

* *Suggested Reading*:

* Moran MA and Kujawinski EB, et al (2022). [Microbial metabolites in the marine carbon cycle](https://rdcu.be/cKnTP). *Nature Microbiology*.
* Kujawinski EB, et al (2023). [Metabolite diversity among representatives of divergent *Prochlorococcus* ecotypes](https://doi.org/10.1128/msystems.01261-22). *mSystems*.
* Wienhausen G, et al (2017). [The exometabolome of two model strains of the *Roseobacter* group: a marketplace of microbial metabolites](https://www.frontiersin.org/articles/10.3389/fmicb.2017.01985/full). *Frontiers in Microbiology*.
* Noriega-Ortega BE, et al (2019). [Does the chemodiversity of bacterial exometabolomes sustain the chemodiversity of marine dissolved organic matter?](https://doi.org/10.3389/fmicb.2019.00215). *Frontiers in microbiology*.

### 29/01/24 :: Course wrap-up: **final discussions and feedback**

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