Feature request. Accept a VCF line

[Peter-J-Freeman]

A user stated

"I presumed that VariantValidator can accept a row of data from a VCF file as input, but that returned an error on the website."

It would be good if we could accepr a VCF line. This would be a really nice alternative to the vcf2hgvs tool. Could be added to the interactive site and the REST APIs

[leicray]

We already support inputs in the format 17-50198002-C-A which is nominally "gnomAD" format. The vcf2gnomad script that I wrote performs the necessary transformation and that could be adapted for this task.

[Peter-J-Freeman]

Good point. That script could be added internally

[leicray]

There is just one wrinkle that would have to be considered. I have seen numerous occasions on which users have submitted invalid VCF files. We would probably have to include a format check on submitted VCF files before having them processed by the vcf2gnomad script.