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There is a talk and reference and diagnostic lab requests for adding O-antigen subtype information due to different phenotypic and clinical manifestations associated with these subtypes. The subtypes of interest are O18ab/ac, O28ac/ab, O112ab/ac, O125ab/ac, O128ab/ac, O141ab/ac, O174ab/ac.
Challenge: Some of the above pairs are very similar genetically and are difficult to resolve.
Possible solution: Incorporate additional metadata into the ECTYPER alleles database. Provide a command line option for user to get subtype information in the O-type field in the output (e.g. --with-O-subtypes). Add additional warning message to alert user to possible limit of resolution due to high degree of similarity between subgroups.
The text was updated successfully, but these errors were encountered:
There is a talk and reference and diagnostic lab requests for adding O-antigen subtype information due to different phenotypic and clinical manifestations associated with these subtypes. The subtypes of interest are O18ab/ac, O28ac/ab, O112ab/ac, O125ab/ac, O128ab/ac, O141ab/ac, O174ab/ac.
Challenge: Some of the above pairs are very similar genetically and are difficult to resolve.
Possible solution: Incorporate additional metadata into the ECTYPER alleles database. Provide a command line option for user to get subtype information in the
O-type
field in the output (e.g.--with-O-subtypes
). Add additional warning message to alert user to possible limit of resolution due to high degree of similarity between subgroups.The text was updated successfully, but these errors were encountered: