diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index b2f9a0ba413..035b6ef0e93 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -12,3 +12,9 @@ jobs:
     with:
       # Turn phpcoverage off because it causes a segfault
       phpcoverage_force_off: true
+      phpunit_skip_suites: framework-cache-only
+      # Ensure we test all in-memory cache factories provided in core
+      extra_jobs: |
+        - phpunit: true
+          phpunit_suite: framework-cache-only
+          install_in_memory_cache_exts: true
diff --git a/_config/cache.yml b/_config/cache.yml
index 9400a527038..5f69d6e4f74 100644
--- a/_config/cache.yml
+++ b/_config/cache.yml
@@ -7,7 +7,6 @@ SilverStripe\Core\Injector\Injector:
     constructor:
       args:
         directory: '`TEMP_PATH`'
-        version: null
       logger: '%$Psr\Log\LoggerInterface'
   Psr\SimpleCache\CacheInterface.cacheblock:
     factory: SilverStripe\Core\Cache\CacheFactory
diff --git a/phpunit.xml.dist b/phpunit.xml.dist
index f435f9a4541..78fdb6bd38a 100644
--- a/phpunit.xml.dist
+++ b/phpunit.xml.dist
@@ -21,6 +21,10 @@ Requires PHPUnit ^9
         <testsuite name="cms">
             <directory>vendor/silverstripe/cms/tests</directory>
         </testsuite>
+        <!-- Cache suite is separate so it only runs what it needs to run. Intentionally also included in core above. -->
+        <testsuite name="framework-cache-only">
+            <directory>tests/php/Core/Cache</directory>
+        </testsuite>
     </testsuites>
     <filter>
         <whitelist addUncoveredFilesFromWhitelist="true">
diff --git a/src/Control/Email/TransportFactory.php b/src/Control/Email/TransportFactory.php
index c8c656c80bc..99ff56919c6 100644
--- a/src/Control/Email/TransportFactory.php
+++ b/src/Control/Email/TransportFactory.php
@@ -12,7 +12,7 @@
  */
 class TransportFactory implements Factory
 {
-    public function create($service, array $params = [])
+    public function create(string $service, array $params = []): object
     {
         $dsn = Environment::getEnv('MAILER_DSN') ?: $params['dsn'];
         $dispatcher = $params['dispatcher'];
diff --git a/src/Core/Cache/AbstractCacheFactory.php b/src/Core/Cache/AbstractCacheFactory.php
new file mode 100644
index 00000000000..3a9251c7348
--- /dev/null
+++ b/src/Core/Cache/AbstractCacheFactory.php
@@ -0,0 +1,100 @@
+<?php
+
+namespace SilverStripe\Core\Cache;
+
+use InvalidArgumentException;
+use Psr\Log\LoggerAwareInterface;
+use Psr\Log\LoggerInterface;
+use Psr\Cache\CacheItemPoolInterface;
+use Psr\SimpleCache\CacheInterface;
+use SilverStripe\Core\Injector\Injector;
+use Symfony\Component\Cache\Psr16Cache;
+
+/**
+ * Abstract implementation of CacheFactory which provides methods to easily instantiate PSR6 and PSR16 cache adapters.
+ */
+abstract class AbstractCacheFactory implements CacheFactory
+{
+    protected ?LoggerInterface $logger;
+
+    /**
+     * @param LoggerInterface $logger Logger instance to assign
+     */
+    public function __construct(LoggerInterface $logger = null)
+    {
+        $this->logger = $logger;
+    }
+
+    /**
+     * Creates an object with a PSR-16 interface, usually from a PSR-6 class name.
+     *
+     * Quick explanation of caching standards:
+     * - Symfony cache implements the PSR-6 standard
+     * - Symfony provides adapters which wrap a PSR-6 backend with a PSR-16 interface
+     * - Silverstripe uses the PSR-16 interface to interact with caches. It does not directly interact with the PSR-6 classes
+     * - Psr\SimpleCache\CacheInterface is the php interface of the PSR-16 standard. All concrete cache classes Silverstripe code interacts with should implement this interface
+     *
+     * Further reading:
+     * - https://symfony.com/doc/current/components/cache/psr6_psr16_adapters.html#using-a-psr-6-cache-object-as-a-psr-16-cache
+     * - https://github.com/php-fig/simple-cache
+     */
+    protected function createCache(
+        string $class,
+        array $args,
+        bool $useInjector = true
+    ): CacheInterface {
+        $classIsPsr6 = is_a($class, CacheItemPoolInterface::class, true);
+        $classIsPsr16 = is_a($class, CacheInterface::class, true);
+        if (!$classIsPsr6 && !$classIsPsr16) {
+            throw new InvalidArgumentException("class $class must implement one of " . CacheItemPoolInterface::class . ' or ' . CacheInterface::class);
+        }
+        $cacheAdapter = $this->instantiateCache($class, $args, $useInjector);
+        $psr16Cache = $this->prepareCacheForUse($cacheAdapter, $useInjector);
+        return $psr16Cache;
+    }
+
+    /**
+     * Prepare a cache adapter for use.
+     * This wraps a PSR6 adapter inside a PSR16 one. It also adds the loggers.
+     */
+    protected function prepareCacheForUse(
+        CacheItemPoolInterface|CacheInterface $cacheAdapter,
+        bool $useInjector
+    ): CacheInterface {
+        $loggerAdded = false;
+        if ($cacheAdapter instanceof CacheItemPoolInterface) {
+            $loggerAdded = $this->addLogger($cacheAdapter);
+            // Wrap the PSR-6 class inside a class with a PSR-16 interface
+            $cacheAdapter = $this->instantiateCache(Psr16Cache::class, [$cacheAdapter], $useInjector);
+        }
+        if (!$loggerAdded) {
+            $this->addLogger($cacheAdapter);
+        }
+        return $cacheAdapter;
+    }
+
+    /**
+     * Instantiates a cache adapter, either via the dependency injector or using the new keyword.
+     */
+    protected function instantiateCache(
+        string $class,
+        array $args,
+        bool $useInjector
+    ): CacheItemPoolInterface|CacheInterface {
+        if ($useInjector) {
+            // Injector is used for in most instances to allow modification of the cache implementations
+            return Injector::inst()->createWithArgs($class, $args);
+        }
+        // ManifestCacheFactory cannot use Injector because config is not available at that point
+        return new $class(...$args);
+    }
+
+    protected function addLogger(CacheItemPoolInterface|CacheInterface $cache): bool
+    {
+        if ($this->logger && ($cache instanceof LoggerAwareInterface)) {
+            $cache->setLogger($this->logger);
+            return true;
+        }
+        return false;
+    }
+}
diff --git a/src/Core/Cache/ApcuCacheFactory.php b/src/Core/Cache/ApcuCacheFactory.php
index 188224063b2..4c5a0803701 100644
--- a/src/Core/Cache/ApcuCacheFactory.php
+++ b/src/Core/Cache/ApcuCacheFactory.php
@@ -2,39 +2,62 @@
 
 namespace SilverStripe\Core\Cache;
 
-use SilverStripe\Core\Injector\Injector;
+use Psr\Cache\CacheItemPoolInterface;
+use Psr\SimpleCache\CacheInterface;
+use RuntimeException;
+use SilverStripe\Control\Director;
+use SilverStripe\Core\Environment;
 use Symfony\Component\Cache\Adapter\ApcuAdapter;
-use Symfony\Component\Cache\Psr16Cache;
 
-class ApcuCacheFactory implements CacheFactory
+/**
+ * Factory to instantiate an ApcuAdapter for use in caching.
+ *
+ * Note that APCu cache may not be shared between your webserver and the CLI.
+ * Flushing the cache from your terminal may not flush the cache used by the webserver.
+ * See https://github.com/symfony/symfony/discussions/54066
+ */
+class ApcuCacheFactory extends AbstractCacheFactory implements InMemoryCacheFactory
 {
     /**
-     * @var string
-     */
-    protected $version;
-
-    /**
-     * @param string $version
+     * @inheritdoc
      */
-    public function __construct($version = null)
+    public function create(string $service, array $params = []): CacheInterface
     {
-        $this->version = $version;
+        $psr6Cache = $this->createPsr6($service, $params);
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+        return $this->prepareCacheForUse($psr6Cache, $useInjector);
     }
 
-    /**
-     * @inheritdoc
-     */
-    public function create($service, array $params = [])
+    public function createPsr6(string $service, array $params = []): CacheItemPoolInterface
     {
+        if (!$this->isSupported()) {
+            throw new RuntimeException('APCu is not supported in the current environment. Cannot use APCu cache.');
+        }
+
         $namespace = isset($params['namespace'])
             ? $params['namespace'] . '_' . md5(BASE_PATH)
             : md5(BASE_PATH);
         $defaultLifetime = isset($params['defaultLifetime']) ? $params['defaultLifetime'] : 0;
-        $psr6Cache = Injector::inst()->createWithArgs(ApcuAdapter::class, [
-            $namespace,
-            $defaultLifetime,
-            $this->version
-        ]);
-        return Injector::inst()->createWithArgs(Psr16Cache::class, [$psr6Cache]);
+        // $version is optional - defaults to null.
+        $version = isset($params['version']) ? $params['version'] : Environment::getEnv('SS_APCU_VERSION');
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+
+        return $this->instantiateCache(
+            ApcuAdapter::class,
+            [$namespace, $defaultLifetime, $version],
+            $useInjector
+        );
+    }
+
+    private function isSupported(): bool
+    {
+        static $isSupported = null;
+        if (null === $isSupported) {
+            // Need to check for CLI because Symfony won't: https://github.com/symfony/symfony/pull/25080
+            $isSupported = Director::is_cli()
+                ? filter_var(ini_get('apc.enable_cli'), FILTER_VALIDATE_BOOL) && ApcuAdapter::isSupported()
+                : ApcuAdapter::isSupported();
+        }
+        return $isSupported;
     }
 }
diff --git a/src/Core/Cache/CacheFactory.php b/src/Core/Cache/CacheFactory.php
index 994ac948226..83efbb68766 100644
--- a/src/Core/Cache/CacheFactory.php
+++ b/src/Core/Cache/CacheFactory.php
@@ -7,14 +7,9 @@
 
 interface CacheFactory extends InjectorFactory
 {
-
     /**
      * Note: While the returned object is used as a singleton (by the originating Injector->get() call),
      * this cache object shouldn't be a singleton itself - it has varying constructor args for the same service name.
-     *
-     * @param string $service
-     * @param array $params
-     * @return CacheInterface
      */
-    public function create($service, array $params = []);
+    public function create(string $service, array $params = []): CacheInterface;
 }
diff --git a/src/Core/Cache/DefaultCacheFactory.php b/src/Core/Cache/DefaultCacheFactory.php
index b82d6f08a2b..5dc712ef18c 100644
--- a/src/Core/Cache/DefaultCacheFactory.php
+++ b/src/Core/Cache/DefaultCacheFactory.php
@@ -2,38 +2,24 @@
 
 namespace SilverStripe\Core\Cache;
 
-use InvalidArgumentException;
-use Psr\Log\LoggerAwareInterface;
+use LogicException;
 use Psr\Log\LoggerInterface;
 use Psr\Cache\CacheItemPoolInterface;
 use Psr\SimpleCache\CacheInterface;
-use SilverStripe\Control\Director;
+use SilverStripe\Core\Environment;
 use SilverStripe\Core\Injector\Injector;
-use Symfony\Component\Cache\Adapter\ApcuAdapter;
 use Symfony\Component\Cache\Adapter\ChainAdapter;
 use Symfony\Component\Cache\Adapter\FilesystemAdapter;
 use Symfony\Component\Cache\Adapter\PhpFilesAdapter;
-use Symfony\Component\Cache\Psr16Cache;
 
 /**
- * Returns the most performant combination of caches available on the system:
- * - `PhpFilesCache` (PHP 7 with opcache enabled)
- * - `ApcuCache` (requires APC) with a `FilesystemCache` fallback (for larger cache volumes)
- * - `FilesystemCache` if none of the above is available
- *
- * Modelled after `Symfony\Component\Cache\Adapter\AbstractAdapter::createSystemCache()`
+ * Creates the following cache adapters:
+ * - `PhpFilesAdapter` (falls back to `FilesystemAdapter` if `PhpFilesAdapter` isn't supported)
+ * - An optional in-memory cache such as Redis, Memcached, or APCu.
  */
-class DefaultCacheFactory implements CacheFactory
+class DefaultCacheFactory extends AbstractCacheFactory
 {
-    /**
-     * @var string Absolute directory path
-     */
-    protected $args = [];
-
-    /**
-     * @var LoggerInterface
-     */
-    protected $logger;
+    protected array $args = [];
 
     /**
      * @param array $args List of global options to merge with args during create()
@@ -42,148 +28,98 @@ class DefaultCacheFactory implements CacheFactory
     public function __construct($args = [], LoggerInterface $logger = null)
     {
         $this->args = $args;
-        $this->logger = $logger;
+        parent::__construct($logger);
     }
 
     /**
      * @inheritdoc
      */
-    public function create($service, array $args = [])
+    public function create(string $service, array $args = []): CacheInterface
     {
         // merge args with default
         $args = array_merge($this->args, $args);
         $namespace = isset($args['namespace']) ? $args['namespace'] : '';
-        $defaultLifetime = isset($args['defaultLifetime']) ? $args['defaultLifetime'] : 0;
+        $defaultLifetime = (int) (isset($args['defaultLifetime']) ? $args['defaultLifetime'] : 0);
         $directory = isset($args['directory']) ? $args['directory'] : null;
-        $version = isset($args['version']) ? $args['version'] : null;
         $useInjector = isset($args['useInjector']) ? $args['useInjector'] : true;
 
         // In-memory caches are typically more resource constrained (number of items and storage space).
         // Give cache consumers an opt-out if they are expecting to create large caches with long lifetimes.
         $useInMemoryCache = isset($args['useInMemoryCache']) ? $args['useInMemoryCache'] : true;
+        $inMemoryCacheFactory = Environment::getEnv('SS_IN_MEMORY_CACHE_FACTORY');
 
-        // Check support
-        $apcuSupported = ($this->isAPCUSupported() && $useInMemoryCache);
-        $phpFilesSupported = $this->isPHPFilesSupported();
-
-        // If apcu isn't supported, phpfiles is the next best preference
-        if (!$apcuSupported && $phpFilesSupported) {
-            return $this->createCache(PhpFilesAdapter::class, [$namespace, $defaultLifetime, $directory], $useInjector);
+        $filesystemCache = $this->instantiateFilesystemCache($namespace, $defaultLifetime, $directory, $useInjector);
+        if (!$useInMemoryCache || !$inMemoryCacheFactory) {
+            return $this->prepareCacheForUse($filesystemCache, $useInjector);
         }
 
-        // Create filesystem cache
-        if (!$apcuSupported) {
-            return $this->createCache(
-                FilesystemAdapter::class,
-                [$namespace, $defaultLifetime, $directory],
-                $useInjector
+        // Check if SS_IN_MEMORY_CACHE_FACTORY is a factory
+        if (!is_a($inMemoryCacheFactory, InMemoryCacheFactory::class, true)) {
+            throw new LogicException(
+                'The value in your SS_IN_MEMORY_CACHE_FACTORY environment variable'
+                . ' is not a valid InMemoryCacheFactory class name'
             );
         }
 
-        // Create PSR6 filesystem + apcu cache's wrapped in a PSR6 chain adapter, then wrap in a PSR16 class
-        $fs = $this->instantiateCache(
-            FilesystemAdapter::class,
-            [$namespace, $defaultLifetime, $directory],
+        // Note that the cache lifetime will be shorter there by default, to ensure there's enough
+        // resources for "hot cache" items as a resource constrained in memory cache.
+        $inMemoryLifetime = (int) ($defaultLifetime / 5);
+        $inMemoryCache = $this->instantiateInMemoryCache(
+            $service,
+            $inMemoryCacheFactory,
+            ['namespace' => $namespace, 'defaultLifetime' => $inMemoryLifetime, 'useInjector' => $useInjector],
             $useInjector
         );
 
-        // Note that the cache lifetime will be shorter there by default, to ensure there's enough
-        // resources for "hot cache" items in APCu as a resource constrained in memory cache.
-        $apcuNamespace = $namespace . ($namespace ? '_' : '') . md5(BASE_PATH);
-        $lifetime = (int) $defaultLifetime / 5;
-        $apcu = $this->instantiateCache(ApcuAdapter::class, [$apcuNamespace, $lifetime, $version], $useInjector);
+        // The ChainAdapter doesn't take a logger, so we need to make sure to add it to the child cache adapters.
+        $this->addLogger($filesystemCache);
 
-        return $this->createCache(ChainAdapter::class, [[$apcu, $fs]], $useInjector);
-    }
-
-    /**
-     * Determine if apcu is supported
-     *
-     * @return bool
-     */
-    protected function isAPCUSupported()
-    {
-        static $apcuSupported = null;
-        if (null === $apcuSupported) {
-            // Need to check for CLI because Symfony won't: https://github.com/symfony/symfony/pull/25080
-            $apcuSupported = Director::is_cli()
-                ? filter_var(ini_get('apc.enable_cli'), FILTER_VALIDATE_BOOL) && ApcuAdapter::isSupported()
-                : ApcuAdapter::isSupported();
-        }
-        return $apcuSupported;
+        return $this->createCache(ChainAdapter::class, [[$inMemoryCache, $filesystemCache]], $useInjector);
     }
 
     /**
      * Determine if PHP files is supported
-     *
-     * @return bool
      */
-    protected function isPHPFilesSupported()
+    protected function isPHPFilesSupported(): bool
     {
         static $phpFilesSupported = null;
         if (null === $phpFilesSupported) {
-            $phpFilesSupported = PhpFilesAdapter::isSupported();
+            // Only consider to be enabled if opcache is enabled in CLI, or else
+            // filesystem cache won't be shared between webserver and CLI.
+            $phpFilesSupported = PhpFilesAdapter::isSupported() &&
+                filter_var(ini_get('opcache.enable_cli'), FILTER_VALIDATE_BOOL);
         }
         return $phpFilesSupported;
     }
 
     /**
-     * Creates an object with a PSR-16 interface, usually from a PSR-6 class name
-     *
-     * Quick explanation of caching standards:
-     * - Symfony cache implements the PSR-6 standard
-     * - Symfony provides adapters which wrap a PSR-6 backend with a PSR-16 interface
-     * - Silverstripe uses the PSR-16 interface to interact with caches. It does not directly interact with the PSR-6 classes
-     * - Psr\SimpleCache\CacheInterface is the php interface of the PSR-16 standard. All concrete cache classes Silverstripe code interacts with should implement this interface
-     *
-     * Further reading:
-     * - https://symfony.com/doc/current/components/cache/psr6_psr16_adapters.html#using-a-psr-6-cache-object-as-a-psr-16-cache
-     * - https://github.com/php-fig/simple-cache
+     * Instantiate the cache adapter for the filesystem cache.
      */
-    protected function createCache(
-        string $class,
-        array $args,
-        bool $useInjector = true
-    ): CacheInterface {
-        $loggerAdded = false;
-        $classIsPsr6 = is_a($class, CacheItemPoolInterface::class, true);
-        $classIsPsr16 = is_a($class, CacheInterface::class, true);
-        if (!$classIsPsr6 && !$classIsPsr16) {
-            throw new InvalidArgumentException("class $class must implement one of " . CacheItemPoolInterface::class . ' or ' . CacheInterface::class);
-        }
-        if ($classIsPsr6) {
-            $psr6Cache = $this->instantiateCache($class, $args, $useInjector);
-            $loggerAdded = $this->addLogger($psr6Cache, $loggerAdded);
-            // Wrap the PSR-6 class inside a class with a PSR-16 interface
-            $psr16Cache = $this->instantiateCache(Psr16Cache::class, [$psr6Cache], $useInjector);
-        } else {
-            $psr16Cache = $this->instantiateCache($class, $args, $useInjector);
-        }
-        if (!$loggerAdded) {
-            $this->addLogger($psr16Cache, $loggerAdded);
-        }
-        return $psr16Cache;
-    }
-
-    private function instantiateCache(
-        string $class,
-        array $args,
+    private function instantiateFilesystemCache(
+        string $namespace,
+        int $defaultLifetime,
+        string $directory,
         bool $useInjector
-    ): CacheItemPoolInterface|CacheInterface {
-        if ($useInjector) {
-            // Injector is used for in most instances to allow modification of the cache implementations
-            return Injector::inst()->createWithArgs($class, $args);
+    ): CacheInterface|CacheItemPoolInterface {
+        if ($this->isPHPFilesSupported()) {
+            return $this->instantiateCache(PhpFilesAdapter::class, [$namespace, $defaultLifetime, $directory], $useInjector);
         }
-        // ManifestCacheFactory cannot use Injector because config is not available at that point
-        return new $class(...$args);
+        return $this->instantiateCache(FilesystemAdapter::class, [$namespace, $defaultLifetime, $directory], $useInjector);
     }
 
-    private function addLogger(CacheItemPoolInterface|CacheInterface $cache): bool
+    /**
+     * Instantiate the cache adapter for the in-memory cache.
+     */
+    private function instantiateInMemoryCache(string $service, string $inMemoryCacheFactory, array $args): CacheItemPoolInterface
     {
-        if ($this->logger && $cache instanceof LoggerAwareInterface) {
-            $cache->setLogger($this->logger);
-            return true;
+        if ($args['useInjector']) {
+            $factory = Injector::inst()->create($inMemoryCacheFactory);
+        } else {
+            $factory = new $inMemoryCacheFactory();
         }
-        return false;
+        /** @var InMemoryCacheFactory $factory */
+        $adapter = $factory->createPsr6($service, $args);
+        $this->addLogger($adapter);
+        return $adapter;
     }
 }
diff --git a/src/Core/Cache/FilesystemCacheFactory.php b/src/Core/Cache/FilesystemCacheFactory.php
index 822f582f54d..4de5c7d3f36 100644
--- a/src/Core/Cache/FilesystemCacheFactory.php
+++ b/src/Core/Cache/FilesystemCacheFactory.php
@@ -2,6 +2,7 @@
 
 namespace SilverStripe\Core\Cache;
 
+use Psr\SimpleCache\CacheInterface;
 use SilverStripe\Core\Injector\Injector;
 use Symfony\Component\Cache\Adapter\FilesystemAdapter;
 use Symfony\Component\Cache\Psr16Cache;
@@ -24,7 +25,7 @@ public function __construct($directory)
     /**
      * @inheritdoc
      */
-    public function create($service, array $params = [])
+    public function create(string $service, array $params = []): CacheInterface
     {
         $psr6Cache = Injector::inst()->createWithArgs(FilesystemAdapter::class, [
             (isset($params['namespace'])) ? $params['namespace'] : '',
diff --git a/src/Core/Cache/InMemoryCacheFactory.php b/src/Core/Cache/InMemoryCacheFactory.php
new file mode 100644
index 00000000000..39bfdade13c
--- /dev/null
+++ b/src/Core/Cache/InMemoryCacheFactory.php
@@ -0,0 +1,17 @@
+<?php
+
+namespace SilverStripe\Core\Cache;
+
+use Psr\Cache\CacheItemPoolInterface;
+
+/**
+ * Interface to be implemented by all cache factories that instantiate in-memory symfony cache adapters.
+ * This allows the cache adapters to be used in conjunction with filesystem cache.
+ */
+interface InMemoryCacheFactory extends CacheFactory
+{
+    /**
+     * Create a PSR6-compliant cache adapter
+     */
+    public function createPsr6(string $service, array $params = []): CacheItemPoolInterface;
+}
diff --git a/src/Core/Cache/ManifestCacheFactory.php b/src/Core/Cache/ManifestCacheFactory.php
index 52d3b294fe2..8c0b9b688f1 100644
--- a/src/Core/Cache/ManifestCacheFactory.php
+++ b/src/Core/Cache/ManifestCacheFactory.php
@@ -33,14 +33,9 @@ public function __construct(array $args = [], LoggerInterface $logger = null)
     }
 
     /**
-     * Note: While the returned object is used as a singleton (by the originating Injector->get() call),
-     * this cache object shouldn't be a singleton itself - it has varying constructor args for the same service name.
-     *
-     * @param string $service The class name of the service.
-     * @param array $params The constructor parameters.
-     * @return CacheInterface
+     * @inheritDoc
      */
-    public function create($service, array $params = [])
+    public function create(string $service, array $params = []): CacheInterface
     {
         // Override default cache generation with SS_MANIFESTCACHE
         $cacheClass = Environment::getEnv('SS_MANIFESTCACHE');
diff --git a/src/Core/Cache/MemcachedCacheFactory.php b/src/Core/Cache/MemcachedCacheFactory.php
index 1752baf5ba9..9dfe1655fc5 100644
--- a/src/Core/Cache/MemcachedCacheFactory.php
+++ b/src/Core/Cache/MemcachedCacheFactory.php
@@ -2,41 +2,52 @@
 
 namespace SilverStripe\Core\Cache;
 
-use SilverStripe\Core\Injector\Injector;
+use Psr\Cache\CacheItemPoolInterface;
 use Symfony\Component\Cache\Adapter\MemcachedAdapter;
-use Symfony\Component\Cache\Psr16Cache;
-use Memcached;
+use Psr\SimpleCache\CacheInterface;
+use RuntimeException;
+use SilverStripe\Core\Environment;
 
-class MemcachedCacheFactory implements CacheFactory
+/**
+ * Factory to instantiate a MemcachedAdapter for use in caching.
+ *
+ * SS_MEMCACHED_DSN must be set in environment variables.
+ * See https://symfony.com/doc/current/components/cache/adapters/memcached_adapter.html#configure-the-connection
+ */
+class MemcachedCacheFactory extends AbstractCacheFactory implements InMemoryCacheFactory
 {
-
-    /**
-     * @var Memcached
-     */
-    protected $memcachedClient;
-
     /**
-     * @param Memcached $memcachedClient
+     * @inheritdoc
      */
-    public function __construct(Memcached $memcachedClient = null)
+    public function create(string $service, array $params = []): CacheInterface
     {
-        $this->memcachedClient = $memcachedClient;
+        $psr6Cache = $this->createPsr6($service, $params);
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+        return $this->prepareCacheForUse($psr6Cache, $useInjector);
     }
 
-    /**
-     * @inheritdoc
-     */
-    public function create($service, array $params = [])
+    public function createPsr6(string $service, array $params = []): CacheItemPoolInterface
     {
+        if (!MemcachedAdapter::isSupported()) {
+            throw new RuntimeException('Memcached is not supported in the current environment. Cannot use Memcached cache.');
+        }
+
+        $dsn = Environment::getEnv('SS_MEMCACHED_DSN');
+        if (!$dsn) {
+            throw new RuntimeException('The SS_MEMCACHED_DSN environment variable must be set to use Memcached cache.');
+        }
+
         $namespace = isset($params['namespace'])
             ? $params['namespace'] . '_' . md5(BASE_PATH)
             : md5(BASE_PATH);
         $defaultLifetime = isset($params['defaultLifetime']) ? $params['defaultLifetime'] : 0;
-        $psr6Cache = Injector::inst()->createWithArgs(MemcachedAdapter::class, [
-            $this->memcachedClient,
-            $namespace,
-            $defaultLifetime
-        ]);
-        return Injector::inst()->createWithArgs(Psr16Cache::class, [$psr6Cache]);
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+        $client = MemcachedAdapter::createConnection($dsn);
+
+        return $this->instantiateCache(
+            MemcachedAdapter::class,
+            [$client, $namespace, $defaultLifetime],
+            $useInjector
+        );
     }
 }
diff --git a/src/Core/Cache/RedisCacheFactory.php b/src/Core/Cache/RedisCacheFactory.php
new file mode 100644
index 00000000000..514b47fc874
--- /dev/null
+++ b/src/Core/Cache/RedisCacheFactory.php
@@ -0,0 +1,64 @@
+<?php
+
+namespace SilverStripe\Core\Cache;
+
+use RuntimeException;
+use Predis\Client as PredisClient;
+use Psr\Cache\CacheItemPoolInterface;
+use Psr\SimpleCache\CacheInterface;
+use Relay\Relay;
+use SilverStripe\Core\Environment;
+use Symfony\Component\Cache\Adapter\RedisAdapter;
+
+/**
+ * Factory to instantiate a RedisAdapter for use in caching.
+ *
+ * One of the "redis" PHP extension, the "predis/predis" package, or the "cachewerk/relay" package is required to use Redis.
+ *
+ * SS_REDIS_DSN must be set in environment variables.
+ * See https://symfony.com/doc/current/components/cache/adapters/redis_adapter.html#configure-the-connection
+ */
+class RedisCacheFactory extends AbstractCacheFactory implements InMemoryCacheFactory
+{
+    /**
+     * @inheritdoc
+     */
+    public function create(string $service, array $params = []): CacheInterface
+    {
+        $psr6Cache = $this->createPsr6($service, $params);
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+        return $this->prepareCacheForUse($psr6Cache, $useInjector);
+    }
+
+    public function createPsr6(string $service, array $params = []): CacheItemPoolInterface
+    {
+        if (!$this->isSupported()) {
+            throw new RuntimeException('Redis is not supported in the current environment. Cannot use Redis cache.');
+        }
+
+        $dsn = Environment::getEnv('SS_REDIS_DSN');
+        if (!$dsn) {
+            throw new RuntimeException('The SS_REDIS_DSN environment variable must be set to use Redis cache.');
+        }
+
+        $namespace = isset($params['namespace'])
+            ? $params['namespace'] . '_' . md5(BASE_PATH)
+            : md5(BASE_PATH);
+        $defaultLifetime = isset($params['defaultLifetime']) ? $params['defaultLifetime'] : 0;
+        $useInjector = isset($params['useInjector']) ? $params['useInjector'] : true;
+        $client = RedisAdapter::createConnection($dsn, ['lazy' => true]);
+
+        return $this->instantiateCache(
+            RedisAdapter::class,
+            [$client, $namespace, $defaultLifetime],
+            $useInjector
+        );
+    }
+
+    public function isSupported()
+    {
+        return class_exists(PredisClient::class) ||
+            class_exists(Relay::class) ||
+            extension_loaded('redis');
+    }
+}
diff --git a/src/Core/Injector/Factory.php b/src/Core/Injector/Factory.php
index 36aaa00e199..c027c40d353 100644
--- a/src/Core/Injector/Factory.php
+++ b/src/Core/Injector/Factory.php
@@ -15,5 +15,5 @@ interface Factory
      * @param array $params The constructor parameters.
      * @return object The created service instances.
      */
-    public function create($service, array $params = []);
+    public function create(string $service, array $params = []): ?object;
 }
diff --git a/src/Core/Injector/InjectionCreator.php b/src/Core/Injector/InjectionCreator.php
index ad91f11d281..6b1ae121a2f 100644
--- a/src/Core/Injector/InjectionCreator.php
+++ b/src/Core/Injector/InjectionCreator.php
@@ -12,19 +12,10 @@ class InjectionCreator implements Factory
     /**
      * Create a new instance of a class
      *
-     * Passing an object for $class will result from using an anonymous class in unit testing, e.g.
-     * Injector::inst()->load([SomeClass::class => ['class' => new class { ... }]]);
-     *
      * @param string|object $class - string: The FQCN of the class, object: A class instance
      */
-    public function create($class, array $params = [])
+    public function create(string $class, array $params = []): object
     {
-        if (is_object($class ?? '')) {
-            $class = get_class($class);
-        }
-        if (!is_string($class ?? '')) {
-            throw new InvalidArgumentException('$class parameter must be a string or an object');
-        }
         if (!class_exists($class)) {
             throw new InjectorNotFoundException("Class {$class} does not exist");
         }
diff --git a/tests/php/Core/Cache/CacheTest.php b/tests/php/Core/Cache/CacheTest.php
deleted file mode 100644
index 228b1121a4f..00000000000
--- a/tests/php/Core/Cache/CacheTest.php
+++ /dev/null
@@ -1,84 +0,0 @@
-<?php
-
-namespace SilverStripe\Core\Tests\Cache;
-
-use Behat\Gherkin\Cache\MemoryCache;
-use Psr\SimpleCache\CacheInterface;
-use SilverStripe\Core\Cache\ApcuCacheFactory;
-use SilverStripe\Core\Cache\MemcachedCacheFactory;
-use SilverStripe\Core\Injector\Injector;
-use SilverStripe\Core\Tests\Cache\CacheTest\MockCache;
-use SilverStripe\Dev\SapphireTest;
-use Symfony\Component\Cache\Psr16Cache;
-use Symfony\Component\Cache\Adapter\ApcuAdapter;
-use Symfony\Component\Cache\Adapter\MemcachedAdapter;
-use Memcached;
-
-class CacheTest extends SapphireTest
-{
-    protected function setUp(): void
-    {
-        parent::setUp();
-
-        Injector::inst()
-            ->load([
-                ApcuCacheFactory::class => [
-                    'constructor' => [ 'version' => 'ss40test' ]
-                ],
-                'MemcachedClient' => Memcached::class,
-                MemcachedCacheFactory::class => [
-                    'constructor' => [ 'memcachedClient' => '%$MemcachedClient' ]
-                ],
-                CacheInterface::class . '.TestApcuCache' =>  [
-                    'factory' => ApcuCacheFactory::class,
-                    'constructor' => [
-                        'namespace' => 'TestApcuCache',
-                        'defaultLifetime' => 2600,
-                    ],
-                ],
-                CacheInterface::class . '.TestMemcache' => [
-                    'factory' => MemcachedCacheFactory::class,
-                    'constructor' => [
-                        'namespace' => 'TestMemCache',
-                        'defaultLifetime' => 5600,
-                    ],
-                ],
-                Psr16Cache::class => MockCache::class,
-                ApcuAdapter::class => MockCache::class,
-                MemcachedAdapter::class => MockCache::class,
-            ]);
-    }
-
-    public function testApcuCacheFactory()
-    {
-        $psr16Cache = Injector::inst()->get(CacheInterface::class . '.TestApcuCache');
-        $this->assertInstanceOf(MockCache::class, $psr16Cache);
-        $this->assertEquals(MockCache::class, get_class($psr16Cache->getArgs()[0]));
-        $this->assertEquals(
-            [
-                'TestApcuCache_' . md5(BASE_PATH),
-                2600,
-                'ss40test'
-            ],
-            $psr16Cache->getArgs()[0]->getArgs()
-        );
-    }
-
-    public function testMemCacheFactory()
-    {
-        if (!class_exists(Memcached::class)) {
-            $this->markTestSkipped('Memcached is not installed');
-        }
-        $psr16Cache = Injector::inst()->get(CacheInterface::class . '.TestMemcache');
-        $this->assertInstanceOf(MockCache::class, $psr16Cache);
-        $this->assertEquals(MockCache::class, get_class($psr16Cache->getArgs()[0]));
-        $this->assertEquals(
-            [
-                new MemCached(),
-                'TestMemCache_' . md5(BASE_PATH),
-                5600
-            ],
-            $psr16Cache->getArgs()[0]->getArgs()
-        );
-    }
-}
diff --git a/tests/php/Core/Cache/DefaultCacheFactoryTest.php b/tests/php/Core/Cache/DefaultCacheFactoryTest.php
new file mode 100644
index 00000000000..9041f4a3ed0
--- /dev/null
+++ b/tests/php/Core/Cache/DefaultCacheFactoryTest.php
@@ -0,0 +1,156 @@
+<?php
+
+namespace SilverStripe\Core\Tests\Cache;
+
+use Monolog\Logger;
+use Predis\Client as PredisClient;
+use ReflectionProperty;
+use Relay\Relay;
+use RuntimeException;
+use SilverStripe\Core\Cache\ApcuCacheFactory;
+use SilverStripe\Core\Cache\DefaultCacheFactory;
+use SilverStripe\Core\Cache\MemcachedCacheFactory;
+use SilverStripe\Core\Cache\RedisCacheFactory;
+use SilverStripe\Core\Environment;
+use SilverStripe\Dev\SapphireTest;
+use Symfony\Component\Cache\Adapter\ApcuAdapter;
+use Symfony\Component\Cache\Adapter\ChainAdapter;
+use Symfony\Component\Cache\Adapter\FilesystemAdapter;
+use Symfony\Component\Cache\Adapter\MemcachedAdapter;
+use Symfony\Component\Cache\Adapter\PhpFilesAdapter;
+use Symfony\Component\Cache\Adapter\RedisAdapter;
+
+class DefaultCacheFactoryTest extends SapphireTest
+{
+    public function provideCreate(): array
+    {
+        $scenarios = [
+            [
+                'args' => [
+                    'useInMemoryCache' => true,
+                    'useInjector' => true,
+                ],
+                'inMemoryCacheFactory' => null,
+            ],
+            [
+                'args' => [
+                    'useInMemoryCache' => false,
+                ],
+                'inMemoryCacheFactory' => null,
+            ],
+            [
+                'args' => [
+                    'useInjector' => false,
+                ],
+                'inMemoryCacheFactory' => null,
+            ],
+        ];
+        $cacheFactories = [
+            null,
+        ];
+        // Add the in-memory cache factories the current test environment supports
+        // If a factory isn't supported and we add it anyway it'll throw an exception.
+        if (filter_var(ini_get('apc.enable_cli'), FILTER_VALIDATE_BOOL)) {
+            $cacheFactories[] = ApcuCacheFactory::class;
+        }
+        if (MemcachedAdapter::isSupported()) {
+            $cacheFactories[] = MemcachedCacheFactory::class;
+        }
+        if (class_exists(PredisClient::class) ||
+            class_exists(Relay::class) ||
+            extension_loaded('redis')
+        ) {
+            $cacheFactories[] = RedisCacheFactory::class;
+        }
+        // Use all of the above test scenarios with each supported cache factory
+        $allScenarios = [];
+        foreach ($cacheFactories as $cacheFactory) {
+            foreach ($scenarios as $scenario) {
+                $scenario['inMemoryCacheFactory'] = $cacheFactory;
+                $allScenarios[] = $scenario;
+            }
+        }
+        return $allScenarios;
+    }
+
+    /**
+     * @dataProvider provideCreate
+     */
+    public function testCreate(array $args, ?string $inMemoryCacheFactory): void
+    {
+        $oldFactoryValue = Environment::getEnv('SS_IN_MEMORY_CACHE_FACTORY');
+        $oldMemcachedDSNValue = Environment::getEnv('SS_MEMCACHED_DSN');
+        $oldRedisDSNValue = Environment::getEnv('SS_REDIS_DSN');
+        Environment::setEnv('SS_IN_MEMORY_CACHE_FACTORY', $inMemoryCacheFactory);
+        // These are obviously not real connections, but it seems a real connection is not required
+        // to just instantiate the cache adapter, which allows us to validate the correct adapter
+        // is instantiated.
+        Environment::setEnv('SS_MEMCACHED_DSN', "memcached://example.com:1234");
+        Environment::setEnv('SS_REDIS_DSN', "redis://password@example.com:1234");
+
+        try {
+            $logger = new Logger('test-cache');
+            $defaultArgs = [
+                'namespace' => __FUNCTION__,
+                'directory' => TEMP_PATH,
+            ];
+            $factory = new DefaultCacheFactory($defaultArgs, $logger);
+            $psr16Wrapper = $factory->create('test-cache', $args);
+
+            $reflectionPoolProperty = new ReflectionProperty($psr16Wrapper, 'pool');
+            $reflectionPoolProperty->setAccessible(true);
+            $cacheBucket = $reflectionPoolProperty->getValue($psr16Wrapper);
+
+            if (!$inMemoryCacheFactory || (isset($args['useInMemoryCache']) && !$args['useInMemoryCache'])) {
+                $filesystemCache = $cacheBucket;
+            } else {
+                $this->assertInstanceOf(ChainAdapter::class, $cacheBucket);
+
+                $reflectionAdaptersProperty = new ReflectionProperty($cacheBucket, 'adapters');
+                $reflectionAdaptersProperty->setAccessible(true);
+                $adapters = $reflectionAdaptersProperty->getValue($cacheBucket);
+
+                $this->assertCount(2, $adapters);
+
+                // in-memory cache always comes first
+                $inMemoryCache = array_shift($adapters);
+                $filesystemCache = array_shift($adapters);
+
+                // Check we have the right adapter for the given factory
+                switch ($inMemoryCacheFactory) {
+                    case RedisCacheFactory::class:
+                        $this->assertInstanceOf(RedisAdapter::class, $inMemoryCache);
+                        break;
+                    case MemcachedCacheFactory::class:
+                        $this->assertInstanceOf(MemcachedAdapter::class, $inMemoryCache);
+                        break;
+                    case ApcuCacheFactory::class:
+                        $this->assertInstanceOf(ApcuAdapter::class, $inMemoryCache);
+                        break;
+                    default:
+                        throw new RuntimeException("Unexpected factory while running test: $inMemoryCacheFactory");
+                }
+
+                // Check the adapter got the right logger
+                $reflectionLoggerProperty = new ReflectionProperty($inMemoryCache, 'logger');
+                $reflectionLoggerProperty->setAccessible(true);
+                $this->assertTrue($logger === $reflectionLoggerProperty->getValue($inMemoryCache));
+            }
+
+            // Check filesystem cache is correct
+            if (filter_var(ini_get('opcache.enable'), FILTER_VALIDATE_BOOL) && filter_var(ini_get('opcache.enable_cli'), FILTER_VALIDATE_BOOL)) {
+                $this->assertInstanceOf(PhpFilesAdapter::class, $filesystemCache);
+            } else {
+                $this->assertInstanceOf(FilesystemAdapter::class, $filesystemCache);
+            }
+            // Check the adapter got the right logger
+            $reflectionLoggerProperty = new ReflectionProperty($filesystemCache, 'logger');
+            $reflectionLoggerProperty->setAccessible(true);
+            $this->assertTrue($logger === $reflectionLoggerProperty->getValue($filesystemCache));
+        } finally {
+            Environment::setEnv('SS_IN_MEMORY_CACHE_FACTORY', $oldFactoryValue);
+            Environment::setEnv('SS_MEMCACHED_DSN', $oldMemcachedDSNValue);
+            Environment::setEnv('SS_REDIS_DSN', $oldRedisDSNValue);
+        }
+    }
+}
diff --git a/tests/php/Core/Injector/InjectorTest.php b/tests/php/Core/Injector/InjectorTest.php
index 9d914feeb93..cb7f7b24173 100644
--- a/tests/php/Core/Injector/InjectorTest.php
+++ b/tests/php/Core/Injector/InjectorTest.php
@@ -1155,24 +1155,25 @@ public function testNest()
 
     public function testAnonymousClass()
     {
+        $class = get_class(new class ('abc') {
+            private string $property;
+            public function __construct(string $value)
+            {
+                $this->property = $value;
+            }
+            public function foo(): string
+            {
+                return $this->property;
+            }
+        });
         Injector::inst()->load([
             'Some\\Project\\Class' => [
-                // the php anonymous class syntax will instantiate a new anonymous class object, with ('abc')
-                // passed to the constructor
-                'class' => new class ('abc') {
-                    private string $property;
-                    public function __construct(string $value)
-                    {
-                        $this->property = $value;
-                    }
-                    public function foo(): string
-                    {
-                        return $this->property;
-                    }
-                }
+                'class' => $class,
             ],
         ]);
         // assert that Injector creates a new instance of the anonymous class, with ('def') passed to the constructor
-        $this->assertSame('def', Injector::inst()->create('Some\\Project\\Class', 'def')->foo());
+        $injectedObject = Injector::inst()->create('Some\\Project\\Class', 'def');
+        $this->assertInstanceOf($class, $injectedObject);
+        $this->assertSame('def', $injectedObject->foo());
     }
 }
diff --git a/tests/php/Core/Injector/InjectorTest/EmptyFactory.php b/tests/php/Core/Injector/InjectorTest/EmptyFactory.php
index e713f4689ac..62fb930a4b3 100644
--- a/tests/php/Core/Injector/InjectorTest/EmptyFactory.php
+++ b/tests/php/Core/Injector/InjectorTest/EmptyFactory.php
@@ -6,7 +6,7 @@
 
 class EmptyFactory implements Factory
 {
-    public function create($service, array $params = [])
+    public function create(string $service, array $params = []): ?object
     {
         return null;
     }
diff --git a/tests/php/Core/Injector/InjectorTest/SSObjectCreator.php b/tests/php/Core/Injector/InjectorTest/SSObjectCreator.php
index 7fff12b3659..868175d2053 100644
--- a/tests/php/Core/Injector/InjectorTest/SSObjectCreator.php
+++ b/tests/php/Core/Injector/InjectorTest/SSObjectCreator.php
@@ -25,7 +25,7 @@ public function __construct($injector)
         $this->injector = $injector;
     }
 
-    public function create($class, array $params = [])
+    public function create(string $class, array $params = []): object
     {
         if (strpos($class ?? '', '(') === false) {
             return parent::create($class, $params);