novo-esp-how-to-use-esm1.ipynb

{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 93,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\u001b[33mWARNING: Running pip as the 'root' user can result in broken permissions and conflicting behaviour with the system package manager. It is recommended to use a virtual environment instead: https://pip.pypa.io/warnings/venv\u001b[0m\u001b[33m\n",
      "\u001b[0m"
     ]
    }
   ],
   "source": [
    "!pip install git+https://github.com/facebookresearch/esm.git -q"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [
    {
     "ename": "ModuleNotFoundError",
     "evalue": "No module named 'esm'",
     "output_type": "error",
     "traceback": [
      "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
      "\u001b[0;31mModuleNotFoundError\u001b[0m                       Traceback (most recent call last)",
      "Input \u001b[0;32mIn [1]\u001b[0m, in \u001b[0;36m<cell line: 4>\u001b[0;34m()\u001b[0m\n\u001b[1;32m      2\u001b[0m \u001b[38;5;28;01mimport\u001b[39;00m \u001b[38;5;21;01mpandas\u001b[39;00m \u001b[38;5;28;01mas\u001b[39;00m \u001b[38;5;21;01mpd\u001b[39;00m\n\u001b[1;32m      3\u001b[0m \u001b[38;5;28;01mimport\u001b[39;00m \u001b[38;5;21;01mtorch\u001b[39;00m\n\u001b[0;32m----> 4\u001b[0m \u001b[38;5;28;01mimport\u001b[39;00m \u001b[38;5;21;01mesm\u001b[39;00m\n\u001b[1;32m      5\u001b[0m \u001b[38;5;28;01mimport\u001b[39;00m \u001b[38;5;21;01mmatplotlib\u001b[39;00m\u001b[38;5;21;01m.\u001b[39;00m\u001b[38;5;21;01mpyplot\u001b[39;00m \u001b[38;5;28;01mas\u001b[39;00m \u001b[38;5;21;01mplt\u001b[39;00m\n\u001b[1;32m      6\u001b[0m \u001b[38;5;28;01mfrom\u001b[39;00m \u001b[38;5;21;01mtqdm\u001b[39;00m\u001b[38;5;21;01m.\u001b[39;00m\u001b[38;5;21;01mnotebook\u001b[39;00m \u001b[38;5;28;01mimport\u001b[39;00m tqdm; tqdm\u001b[38;5;241m.\u001b[39mpandas()\n",
      "\u001b[0;31mModuleNotFoundError\u001b[0m: No module named 'esm'"
     ]
    }
   ],
   "source": [
    "import numpy as np\n",
    "import pandas as pd\n",
    "import torch\n",
    "import esm\n",
    "import matplotlib.pyplot as plt\n",
    "from tqdm.notebook import tqdm; tqdm.pandas()\n",
    "import gc"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "!pip install -Uqq fastbook"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "from fastbook import *"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {},
   "outputs": [],
   "source": [
    "df = pd.read_csv('df_combine.csv')\n",
    "test_df = pd.read_csv('test_combine.csv')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Seed"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [],
   "source": [
    "def seed_everything(seed=42):\n",
    "    random.seed(seed)\n",
    "    os.environ['PYTHONHASHSEED'] = str(seed)\n",
    "    np.random.seed(seed)\n",
    "    torch.manual_seed(seed)\n",
    "    torch.cuda.manual_seed(seed)\n",
    "    torch.backends.cudnn.deterministic = True\n",
    "    \n",
    "seed_everything(seed=42)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Get esm feature"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 95,
   "metadata": {
    "collapsed": true,
    "jupyter": {
     "outputs_hidden": true
    },
    "tags": []
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Downloading: \"https://dl.fbaipublicfiles.com/fair-esm/models/esm2_t33_650M_UR50D.pt\" to /root/.cache/torch/hub/checkpoints/esm2_t33_650M_UR50D.pt\n",
      "Downloading: \"https://dl.fbaipublicfiles.com/fair-esm/regression/esm2_t33_650M_UR50D-contact-regression.pt\" to /root/.cache/torch/hub/checkpoints/esm2_t33_650M_UR50D-contact-regression.pt\n"
     ]
    },
    {
     "data": {
      "text/plain": [
       "ESM2(\n",
       "  (embed_tokens): Embedding(33, 1280, padding_idx=1)\n",
       "  (layers): ModuleList(\n",
       "    (0): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (1): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (2): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (3): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (4): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (5): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (6): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (7): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (8): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (9): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (10): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (11): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (12): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (13): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (14): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (15): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (16): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (17): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (18): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (19): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (20): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (21): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (22): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (23): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (24): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (25): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (26): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (27): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (28): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (29): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (30): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (31): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "    (32): TransformerLayer(\n",
       "      (self_attn): MultiheadAttention(\n",
       "        (k_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (v_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (q_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (out_proj): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "        (rot_emb): RotaryEmbedding()\n",
       "      )\n",
       "      (self_attn_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "      (fc1): Linear(in_features=1280, out_features=5120, bias=True)\n",
       "      (fc2): Linear(in_features=5120, out_features=1280, bias=True)\n",
       "      (final_layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "    )\n",
       "  )\n",
       "  (contact_head): ContactPredictionHead(\n",
       "    (regression): Linear(in_features=660, out_features=1, bias=True)\n",
       "    (activation): Sigmoid()\n",
       "  )\n",
       "  (emb_layer_norm_after): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "  (lm_head): RobertaLMHead(\n",
       "    (dense): Linear(in_features=1280, out_features=1280, bias=True)\n",
       "    (layer_norm): LayerNorm((1280,), eps=1e-05, elementwise_affine=True)\n",
       "  )\n",
       ")"
      ]
     },
     "execution_count": 95,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# Load ESM-2 model\n",
    "model, alphabet = esm.pretrained.esm2_t33_650M_UR50D()\n",
    "batch_converter = alphabet.get_batch_converter()\n",
    "model.eval()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 96,
   "metadata": {
    "tags": []
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Transferred model to GPU\n"
     ]
    }
   ],
   "source": [
    "if torch.cuda.is_available():\n",
    "    model = model.cuda()\n",
    "    print(\"Transferred model to GPU\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 97,
   "metadata": {},
   "outputs": [],
   "source": [
    "def get_feature(r,colname):\n",
    "    data = [('protein',r[colname])]\n",
    "    labels, strs, tokens = batch_converter(data)\n",
    "    with torch.no_grad(): \n",
    "        results = model(tokens.cuda(), repr_layers=[33], return_contacts=True)\n",
    "    rpr = results[\"representations\"][33].squeeze()\n",
    "    rpr=rpr[1 : len(r[colname]) + 1].mean(0).detach().cpu().numpy()\n",
    "    \n",
    "    del results, labels, strs, tokens, data #especially need to delete those on cuda: tokens, results\n",
    "\n",
    "    return rpr"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 98,
   "metadata": {},
   "outputs": [],
   "source": [
    "def get_feature_df(df,colname):\n",
    "    series = df.progress_apply(lambda r: get_feature(r,colname), axis=1)\n",
    "    df_feature = pd.DataFrame(series.tolist())\n",
    "    return df_feature"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### In order to process esm, delete long sequence"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [],
   "source": [
    "df['len'] = df.mut_seq.apply(len)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df.query('len < 1000').len.plot.hist(bins=200);"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {},
   "outputs": [],
   "source": [
    "df = df.query('len < 800')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 42,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "75586a6dc9d046528c46fe3b0299d0e1",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/5139 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "fedecc8049ea4587be36f8cbf410bc2f",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/5139 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "mut_feature = get_feature_df(df,'mut_seq')\n",
    "wt_feature = get_feature_df(df,'wt_seq')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 90,
   "metadata": {},
   "outputs": [],
   "source": [
    "test = pd.read_csv('test_sub.csv')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 99,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "7dfb431f842e4a53af65789c009b2d65",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/2413 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "89f506b6fa124573ac01c3e06b1adfa8",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/2413 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "test_mut = get_feature_df(test,'mut_seq')\n",
    "test_wt = get_feature_df(test,'wt_seq')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 101,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "0       221\n",
       "1       221\n",
       "2       220\n",
       "3       221\n",
       "4       221\n",
       "       ... \n",
       "2408    221\n",
       "2409    221\n",
       "2410    221\n",
       "2411    221\n",
       "2412    221\n",
       "Name: mut_seq, Length: 2413, dtype: int64"
      ]
     },
     "execution_count": 101,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "test_combine.mut_seq.transform(len)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 110,
   "metadata": {},
   "outputs": [],
   "source": [
    "test_feature = test_wt - test_mut\n",
    "test_combine = pd.concat([test, test_feature],axis=1)\n",
    "test_combine['len'] = test_combine.mut_seq.transform(len)\n",
    "test_combine.to_csv('test_combine.csv')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 113,
   "metadata": {},
   "outputs": [],
   "source": [
    "test_combine.rename(columns={'pH':'pH2'},inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 146,
   "metadata": {},
   "outputs": [],
   "source": [
    "test_df=test_combine.copy()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 157,
   "metadata": {},
   "outputs": [],
   "source": [
    "test_df.to_csv('test_combine.csv',index=False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [
    {
     "ename": "NameError",
     "evalue": "name 'pd' is not defined",
     "output_type": "error",
     "traceback": [
      "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
      "\u001b[0;31mNameError\u001b[0m                                 Traceback (most recent call last)",
      "Input \u001b[0;32mIn [1]\u001b[0m, in \u001b[0;36m<cell line: 1>\u001b[0;34m()\u001b[0m\n\u001b[0;32m----> 1\u001b[0m test_df \u001b[38;5;241m=\u001b[39m \u001b[43mpd\u001b[49m\u001b[38;5;241m.\u001b[39mread_csv(\u001b[38;5;124m'\u001b[39m\u001b[38;5;124mtest_combine.csv\u001b[39m\u001b[38;5;124m'\u001b[39m)\n",
      "\u001b[0;31mNameError\u001b[0m: name 'pd' is not defined"
     ]
    }
   ],
   "source": [
    "test_df = pd.read_csv('test_combine.csv')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Get feature differences"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "diff_feature = wt_feature - mut_feature"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 54,
   "metadata": {},
   "outputs": [],
   "source": [
    "df.reset_index(inplace=True) #make sure the index of two concat dfs are same\n",
    "df_combine = pd.concat([df, diff_feature], axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine = pd.read_csv('with_esm_feature.csv')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Filter out data with dTm"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine = df_combine.dropna(subset = 'Tm')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Fill pH NaN"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [],
   "source": [
    "pd.options.mode.chained_assignment = None"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine['pH2'] = df_combine.groupby('group').pH.transform(lambda x: x.fillna(x.mean()))"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### for those groups that don't have pH or pH.mean() at all, fill with 8"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine.pH2.fillna(8, inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "0"
      ]
     },
     "execution_count": 10,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df_combine.pH2.isna().sum()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Normalize Targets"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine['y_max'] = df_combine.groupby('group').Tm.transform(lambda x: x/x.max())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine['y_normalize'] = df_combine.groupby('group').Tm.transform(lambda x: (x-x.mean())/x.std() )"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "(0, 52)"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df_combine.y_max.isna().sum(),df_combine.y_normalize.isna().sum()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_combine.y_max.plot.hist(bins=50);"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_combine.y_normalize.plot.hist(bins=50);"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Interestingly, there are some groups with same Tm all the time (std=0), so filter out"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array([37, 66, 68, 69])"
      ]
     },
     "execution_count": 18,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df_combine[df_combine.groupby('group').Tm.transform(lambda x: x.std()==0)].group.unique()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array([37, 66, 68, 69])"
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df_combine[df_combine.y_normalize.isna()].group.unique()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine = df_combine.dropna(subset='y_normalize')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "False"
      ]
     },
     "execution_count": 21,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "37 in df_combine.group.to_list()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "(4108, 1292)"
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df_combine.shape"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 116,
   "metadata": {},
   "outputs": [],
   "source": [
    "df = df[df.group!=33]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Check how many per group; remove group count < 20"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_combine.groupby('group').mut_seq.count().plot.bar();"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine = df_combine[df_combine.groupby('group').mut_seq.transform(lambda x: x.count()>=20)]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### check the distribution of y_normalize after filter"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_combine.y_normalize.plot.hist(bins=50);"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 117,
   "metadata": {},
   "outputs": [],
   "source": [
    "df.reset_index(drop=True, inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 118,
   "metadata": {},
   "outputs": [],
   "source": [
    "df.to_csv('df_combine.csv', index=False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 119,
   "metadata": {},
   "outputs": [],
   "source": [
    "df = pd.read_csv('df_combine.csv')\n"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Define feature columns"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {},
   "outputs": [],
   "source": [
    "esm_feature = [str(i) for i in range(1280)]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {},
   "outputs": [],
   "source": [
    "others = ['pH2','len']"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {},
   "outputs": [],
   "source": [
    "features = esm_feature + others"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Make Dataset"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "metadata": {},
   "outputs": [],
   "source": [
    "from torch.utils.data import Dataset"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {},
   "outputs": [],
   "source": [
    "class MyDataset(Dataset):\n",
    "    def __init__(self,df, features,target):\n",
    "        self.df = df\n",
    "        self.x = df.loc[:,features].values*1000\n",
    "        self.y = df.loc[:,target].values\n",
    "    def __len__(self): return len(self.df)\n",
    "    def __getitem__(self, idx):\n",
    "        feature = torch.as_tensor(self.x[idx],dtype=torch.float32)\n",
    "        label = torch.as_tensor(self.y[idx],dtype=torch.float32)\n",
    "        return feature,label"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {},
   "outputs": [],
   "source": [
    "class TestDataset(Dataset):\n",
    "    def __init__(self,df, features):\n",
    "        self.df = df\n",
    "        self.x = df.loc[:,features].values*1000\n",
    "        # self.y = df.loc[:,target].values\n",
    "    def __len__(self): return len(self.df)\n",
    "    def __getitem__(self, idx):\n",
    "        feature = torch.as_tensor(self.x[idx],dtype=torch.float32)\n",
    "        # label = torch.as_tensor(self.y[idx],dtype=torch.float32)\n",
    "        return feature"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [],
   "source": [
    "dataset = MyDataset(df,features,'y_normalize')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "(tensor([ 2.2642e+00, -2.7809e+00,  2.9928e+00,  ..., -1.4168e+00,  6.5000e+03,  1.6400e+05]),\n",
       " tensor(0.9831))"
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "dataset[3]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### DataLoader"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [],
   "source": [
    "dl = DataLoader(dataset,bs=8,shuffle=True,num_workers=4)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [],
   "source": [
    "x, y = dl.one_batch()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Model"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/usr/local/lib/python3.9/dist-packages/torch/nn/modules/lazy.py:178: UserWarning: Lazy modules are a new feature under heavy development so changes to the API or functionality can happen at any moment.\n",
      "  warnings.warn('Lazy modules are a new feature under heavy development '\n"
     ]
    }
   ],
   "source": [
    "model1 = nn.Sequential(nn.LazyLinear(500),\n",
    "                      nn.LazyBatchNorm1d(),\n",
    "                      nn.LazyLinear(200),\n",
    "                      nn.LazyBatchNorm1d(), \n",
    "                      nn.LazyLinear(1))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [],
   "source": [
    "class Model2(Module):\n",
    "    def __init__(self, num_features, num_targets, hidden_size):\n",
    "        cha_1 = 256\n",
    "        cha_2 = 512\n",
    "        cha_3 = 512\n",
    "\n",
    "        cha_1_reshape = int(hidden_size/cha_1)\n",
    "        cha_po_1 = int(hidden_size/cha_1/2)\n",
    "        cha_po_2 = int(hidden_size/cha_1/2/2) * cha_3\n",
    "\n",
    "        self.cha_1 = cha_1\n",
    "        self.cha_2 = cha_2\n",
    "        self.cha_3 = cha_3\n",
    "        self.cha_1_reshape = cha_1_reshape\n",
    "        self.cha_po_1 = cha_po_1\n",
    "        self.cha_po_2 = cha_po_2\n",
    "\n",
    "        self.batch_norm1 = nn.BatchNorm1d(num_features)\n",
    "        self.dropout1 = nn.Dropout(0.1)\n",
    "        self.dense1 = nn.utils.weight_norm(nn.Linear(num_features, hidden_size))\n",
    "\n",
    "        self.batch_norm_c1 = nn.BatchNorm1d(cha_1)\n",
    "        self.dropout_c1 = nn.Dropout(0.1)\n",
    "        self.conv1 = nn.utils.weight_norm(nn.Conv1d(cha_1,cha_2, kernel_size = 5, stride = 1, padding=2,  bias=False),dim=None)\n",
    "\n",
    "        self.ave_po_c1 = nn.AdaptiveAvgPool1d(output_size = cha_po_1)\n",
    "\n",
    "        self.batch_norm_c2 = nn.BatchNorm1d(cha_2)\n",
    "        self.dropout_c2 = nn.Dropout(0.1)\n",
    "        self.conv2 = nn.utils.weight_norm(nn.Conv1d(cha_2,cha_2, kernel_size = 3, stride = 1, padding=1, bias=True),dim=None)\n",
    "\n",
    "        self.batch_norm_c2_1 = nn.BatchNorm1d(cha_2)\n",
    "        self.dropout_c2_1 = nn.Dropout(0.3)\n",
    "        self.conv2_1 = nn.utils.weight_norm(nn.Conv1d(cha_2,cha_2, kernel_size = 3, stride = 1, padding=1, bias=True),dim=None)\n",
    "\n",
    "        self.batch_norm_c2_2 = nn.BatchNorm1d(cha_2)\n",
    "        self.dropout_c2_2 = nn.Dropout(0.2)\n",
    "        self.conv2_2 = nn.utils.weight_norm(nn.Conv1d(cha_2,cha_3, kernel_size = 5, stride = 1, padding=2, bias=True),dim=None)\n",
    "\n",
    "        self.max_po_c2 = nn.MaxPool1d(kernel_size=4, stride=2, padding=1)\n",
    "\n",
    "        self.flt = nn.Flatten()\n",
    "\n",
    "        self.batch_norm3 = nn.BatchNorm1d(cha_po_2)\n",
    "        self.dropout3 = nn.Dropout(0.2)\n",
    "        self.dense3 = nn.utils.weight_norm(nn.Linear(cha_po_2, num_targets))\n",
    "\n",
    "    def forward(self, x):\n",
    "\n",
    "        x = self.batch_norm1(x)\n",
    "        x = self.dropout1(x)\n",
    "        x = F.celu(self.dense1(x), alpha=0.06)\n",
    "\n",
    "        x = x.reshape(x.shape[0],self.cha_1,\n",
    "                      self.cha_1_reshape)\n",
    "\n",
    "        x = self.batch_norm_c1(x)\n",
    "        x = self.dropout_c1(x)\n",
    "        x = F.relu(self.conv1(x))\n",
    "\n",
    "        x = self.ave_po_c1(x)\n",
    "\n",
    "        x = self.batch_norm_c2(x)\n",
    "        x = self.dropout_c2(x)\n",
    "        x = F.relu(self.conv2(x))\n",
    "        x_s = x\n",
    "\n",
    "        x = self.batch_norm_c2_1(x)\n",
    "        x = self.dropout_c2_1(x)\n",
    "        x = F.relu(self.conv2_1(x))\n",
    "\n",
    "        x = self.batch_norm_c2_2(x)\n",
    "        x = self.dropout_c2_2(x)\n",
    "        x = F.relu(self.conv2_2(x))\n",
    "        x =  x * x_s\n",
    "\n",
    "        x = self.max_po_c2(x)\n",
    "\n",
    "        x = self.flt(x)\n",
    "\n",
    "        x = self.batch_norm3(x)\n",
    "        x = self.dropout3(x)\n",
    "        x = self.dense3(x)\n",
    "\n",
    "        return x"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [],
   "source": [
    "num_features = x.shape[1]\n",
    "num_targets=1\n",
    "hidden_size=4096"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [],
   "source": [
    "x = x.to(device)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "metadata": {},
   "outputs": [],
   "source": [
    "model = model.to(device)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [],
   "source": [
    "model = Model2(num_features,num_targets,hidden_size)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 36,
   "metadata": {},
   "outputs": [],
   "source": [
    "pred = model(x)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "tensor([[-0.9853],\n",
       "        [ 0.8692],\n",
       "        [ 0.8756],\n",
       "        [-0.0468],\n",
       "        [-0.3934],\n",
       "        [-0.2871],\n",
       "        [ 0.4067],\n",
       "        [ 0.3020]], grad_fn=<AddmmBackward0>)"
      ]
     },
     "execution_count": 27,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "pred"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Loss"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "metadata": {},
   "outputs": [],
   "source": [
    "loss_fn = MSELossFlat()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "TensorBase(0.6101, grad_fn=<AliasBackward0>)"
      ]
     },
     "execution_count": 29,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "loss_fn(pred, y)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Prepare training"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "metadata": {},
   "outputs": [],
   "source": [
    "device = \"cuda\" if torch.cuda.is_available() else \"cpu\""
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [],
   "source": [
    "# learn = Learner(dl,model,loss_func=MSELossFlat())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 32,
   "metadata": {},
   "outputs": [],
   "source": [
    "model = model2.cuda()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Optimizer"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "metadata": {},
   "outputs": [],
   "source": [
    "optimizer = torch.optim.Adam(model.parameters(), lr=1e-3, weight_decay=1e-5)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### Scheduler"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "from torch.optim.lr_scheduler import OneCycleLR"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [],
   "source": [
    "scheduler = OneCycleLR(optimizer, max_lr=1e-2,steps_per_epoch=len(dl),div_factor=1e3, epochs=25,pct_start=0.1)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Training OLOS"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "metadata": {},
   "outputs": [],
   "source": [
    "def train_fn(dl,model,loss_fn, optimizer,scheduler):\n",
    "    \n",
    "    model.train()\n",
    "    final_loss=0\n",
    "    \n",
    "    for x, y in dl:\n",
    "        x, y = x.to(device), y.to(device)\n",
    "\n",
    "        # Compute prediction error\n",
    "        pred = model(x)\n",
    "        loss = loss_fn(pred, y)\n",
    "\n",
    "        # Backpropagation\n",
    "        optimizer.zero_grad()\n",
    "        loss.backward()\n",
    "        optimizer.step()\n",
    "        scheduler.step()\n",
    "        \n",
    "        final_loss += loss.item()\n",
    "        \n",
    "    final_loss /= len(dl)\n",
    "    \n",
    "    return final_loss"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 38,
   "metadata": {},
   "outputs": [],
   "source": [
    "def valid_fn(dl,model,loss_fn):\n",
    "    model.eval()\n",
    "    final_loss = 0\n",
    "    preds = []\n",
    "    with torch.no_grad():\n",
    "        for x,y in dl:\n",
    "            x, y = x.to(device), y.to(device)\n",
    "            pred = model(x)\n",
    "            loss = loss_fn(pred, y)\n",
    "\n",
    "            final_loss += loss.item()\n",
    "            preds.append(pred.detach().cpu().numpy())\n",
    "        \n",
    "    final_loss /= len(dl)\n",
    "    preds = np.concatenate(preds)\n",
    "    \n",
    "    return final_loss, preds"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 39,
   "metadata": {},
   "outputs": [],
   "source": [
    "def test_fn(dl,model):\n",
    "    model.eval()\n",
    "    preds = []\n",
    "    with torch.no_grad():\n",
    "        for x in dl:\n",
    "            x = x.to(device)\n",
    "            pred = model(x)\n",
    "            preds.append(pred.detach().cpu().numpy())\n",
    "        \n",
    "    preds = np.concatenate(preds)\n",
    "    \n",
    "    return preds"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### GroupKFold"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 40,
   "metadata": {},
   "outputs": [],
   "source": [
    "from sklearn.model_selection import GroupKFold"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 41,
   "metadata": {},
   "outputs": [],
   "source": [
    "from scipy import stats"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "model = Model2(num_features,num_targets,hidden_size)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 46,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "Model2(\n",
       "  (batch_norm1): BatchNorm1d(1282, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout1): Dropout(p=0.1, inplace=False)\n",
       "  (dense1): Linear(in_features=1282, out_features=4096, bias=True)\n",
       "  (batch_norm_c1): BatchNorm1d(256, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout_c1): Dropout(p=0.1, inplace=False)\n",
       "  (conv1): Conv1d(256, 512, kernel_size=(5,), stride=(1,), padding=(2,), bias=False)\n",
       "  (ave_po_c1): AdaptiveAvgPool1d(output_size=8)\n",
       "  (batch_norm_c2): BatchNorm1d(512, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout_c2): Dropout(p=0.1, inplace=False)\n",
       "  (conv2): Conv1d(512, 512, kernel_size=(3,), stride=(1,), padding=(1,))\n",
       "  (batch_norm_c2_1): BatchNorm1d(512, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout_c2_1): Dropout(p=0.3, inplace=False)\n",
       "  (conv2_1): Conv1d(512, 512, kernel_size=(3,), stride=(1,), padding=(1,))\n",
       "  (batch_norm_c2_2): BatchNorm1d(512, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout_c2_2): Dropout(p=0.2, inplace=False)\n",
       "  (conv2_2): Conv1d(512, 512, kernel_size=(5,), stride=(1,), padding=(2,))\n",
       "  (max_po_c2): MaxPool1d(kernel_size=4, stride=2, padding=1, dilation=1, ceil_mode=False)\n",
       "  (flt): Flatten(start_dim=1, end_dim=-1)\n",
       "  (batch_norm3): BatchNorm1d(2048, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (dropout3): Dropout(p=0.2, inplace=False)\n",
       "  (dense3): Linear(in_features=2048, out_features=1, bias=True)\n",
       ")"
      ]
     },
     "execution_count": 46,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "model.to(device)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 48,
   "metadata": {},
   "outputs": [
    {
     "ename": "ValueError",
     "evalue": "Expected more than 1 value per channel when training, got input size torch.Size([1, 1282])",
     "output_type": "error",
     "traceback": [
      "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
      "\u001b[0;31mValueError\u001b[0m                                Traceback (most recent call last)",
      "Input \u001b[0;32mIn [48]\u001b[0m, in \u001b[0;36m<cell line: 4>\u001b[0;34m()\u001b[0m\n\u001b[1;32m      5\u001b[0m x, y \u001b[38;5;241m=\u001b[39m x\u001b[38;5;241m.\u001b[39mto(device), y\u001b[38;5;241m.\u001b[39mto(device)\n\u001b[1;32m      7\u001b[0m \u001b[38;5;66;03m# Compute prediction error\u001b[39;00m\n\u001b[0;32m----> 8\u001b[0m pred \u001b[38;5;241m=\u001b[39m \u001b[43mmodel\u001b[49m\u001b[43m(\u001b[49m\u001b[43mx\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m      9\u001b[0m loss \u001b[38;5;241m=\u001b[39m loss_fn(pred, y)\n\u001b[1;32m     11\u001b[0m \u001b[38;5;66;03m# Backpropagation\u001b[39;00m\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/module.py:1130\u001b[0m, in \u001b[0;36mModule._call_impl\u001b[0;34m(self, *input, **kwargs)\u001b[0m\n\u001b[1;32m   1126\u001b[0m \u001b[38;5;66;03m# If we don't have any hooks, we want to skip the rest of the logic in\u001b[39;00m\n\u001b[1;32m   1127\u001b[0m \u001b[38;5;66;03m# this function, and just call forward.\u001b[39;00m\n\u001b[1;32m   1128\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_backward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_pre_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_backward_hooks\n\u001b[1;32m   1129\u001b[0m         \u001b[38;5;129;01mor\u001b[39;00m _global_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_forward_pre_hooks):\n\u001b[0;32m-> 1130\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mforward_call\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   1131\u001b[0m \u001b[38;5;66;03m# Do not call functions when jit is used\u001b[39;00m\n\u001b[1;32m   1132\u001b[0m full_backward_hooks, non_full_backward_hooks \u001b[38;5;241m=\u001b[39m [], []\n",
      "Input \u001b[0;32mIn [22]\u001b[0m, in \u001b[0;36mModel2.forward\u001b[0;34m(self, x)\u001b[0m\n\u001b[1;32m     48\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21mforward\u001b[39m(\u001b[38;5;28mself\u001b[39m, x):\n\u001b[0;32m---> 50\u001b[0m     x \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbatch_norm1\u001b[49m\u001b[43m(\u001b[49m\u001b[43mx\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m     51\u001b[0m     x \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mdropout1(x)\n\u001b[1;32m     52\u001b[0m     x \u001b[38;5;241m=\u001b[39m F\u001b[38;5;241m.\u001b[39mcelu(\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mdense1(x), alpha\u001b[38;5;241m=\u001b[39m\u001b[38;5;241m0.06\u001b[39m)\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/module.py:1130\u001b[0m, in \u001b[0;36mModule._call_impl\u001b[0;34m(self, *input, **kwargs)\u001b[0m\n\u001b[1;32m   1126\u001b[0m \u001b[38;5;66;03m# If we don't have any hooks, we want to skip the rest of the logic in\u001b[39;00m\n\u001b[1;32m   1127\u001b[0m \u001b[38;5;66;03m# this function, and just call forward.\u001b[39;00m\n\u001b[1;32m   1128\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_backward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_pre_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_backward_hooks\n\u001b[1;32m   1129\u001b[0m         \u001b[38;5;129;01mor\u001b[39;00m _global_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_forward_pre_hooks):\n\u001b[0;32m-> 1130\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mforward_call\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   1131\u001b[0m \u001b[38;5;66;03m# Do not call functions when jit is used\u001b[39;00m\n\u001b[1;32m   1132\u001b[0m full_backward_hooks, non_full_backward_hooks \u001b[38;5;241m=\u001b[39m [], []\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/batchnorm.py:168\u001b[0m, in \u001b[0;36m_BatchNorm.forward\u001b[0;34m(self, input)\u001b[0m\n\u001b[1;32m    161\u001b[0m     bn_training \u001b[38;5;241m=\u001b[39m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mrunning_mean \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m) \u001b[38;5;129;01mand\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mrunning_var \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m)\n\u001b[1;32m    163\u001b[0m \u001b[38;5;124mr\u001b[39m\u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[1;32m    164\u001b[0m \u001b[38;5;124;03mBuffers are only updated if they are to be tracked and we are in training mode. Thus they only need to be\u001b[39;00m\n\u001b[1;32m    165\u001b[0m \u001b[38;5;124;03mpassed when the update should occur (i.e. in training mode when they are tracked), or when buffer stats are\u001b[39;00m\n\u001b[1;32m    166\u001b[0m \u001b[38;5;124;03mused for normalization (i.e. in eval mode when buffers are not None).\u001b[39;00m\n\u001b[1;32m    167\u001b[0m \u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[0;32m--> 168\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mF\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbatch_norm\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m    169\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\n\u001b[1;32m    170\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;66;43;03m# If buffers are not to be tracked, ensure that they won't be updated\u001b[39;49;00m\n\u001b[1;32m    171\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrunning_mean\u001b[49m\n\u001b[1;32m    172\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43;01mif\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mnot\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtraining\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mor\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtrack_running_stats\u001b[49m\n\u001b[1;32m    173\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43;01melse\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mNone\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m    174\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrunning_var\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mif\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mnot\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtraining\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mor\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtrack_running_stats\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;28;43;01melse\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mNone\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m    175\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mweight\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    176\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbias\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    177\u001b[0m \u001b[43m    \u001b[49m\u001b[43mbn_training\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    178\u001b[0m \u001b[43m    \u001b[49m\u001b[43mexponential_average_factor\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    179\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43meps\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    180\u001b[0m \u001b[43m\u001b[49m\u001b[43m)\u001b[49m\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/functional.py:2436\u001b[0m, in \u001b[0;36mbatch_norm\u001b[0;34m(input, running_mean, running_var, weight, bias, training, momentum, eps)\u001b[0m\n\u001b[1;32m   2423\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m handle_torch_function(\n\u001b[1;32m   2424\u001b[0m         batch_norm,\n\u001b[1;32m   2425\u001b[0m         (\u001b[38;5;28minput\u001b[39m, running_mean, running_var, weight, bias),\n\u001b[0;32m   (...)\u001b[0m\n\u001b[1;32m   2433\u001b[0m         eps\u001b[38;5;241m=\u001b[39meps,\n\u001b[1;32m   2434\u001b[0m     )\n\u001b[1;32m   2435\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m training:\n\u001b[0;32m-> 2436\u001b[0m     \u001b[43m_verify_batch_size\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43msize\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   2438\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m torch\u001b[38;5;241m.\u001b[39mbatch_norm(\n\u001b[1;32m   2439\u001b[0m     \u001b[38;5;28minput\u001b[39m, weight, bias, running_mean, running_var, training, momentum, eps, torch\u001b[38;5;241m.\u001b[39mbackends\u001b[38;5;241m.\u001b[39mcudnn\u001b[38;5;241m.\u001b[39menabled\n\u001b[1;32m   2440\u001b[0m )\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/functional.py:2404\u001b[0m, in \u001b[0;36m_verify_batch_size\u001b[0;34m(size)\u001b[0m\n\u001b[1;32m   2402\u001b[0m     size_prods \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m=\u001b[39m size[i \u001b[38;5;241m+\u001b[39m \u001b[38;5;241m2\u001b[39m]\n\u001b[1;32m   2403\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m size_prods \u001b[38;5;241m==\u001b[39m \u001b[38;5;241m1\u001b[39m:\n\u001b[0;32m-> 2404\u001b[0m     \u001b[38;5;28;01mraise\u001b[39;00m \u001b[38;5;167;01mValueError\u001b[39;00m(\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mExpected more than 1 value per channel when training, got input size \u001b[39m\u001b[38;5;132;01m{}\u001b[39;00m\u001b[38;5;124m\"\u001b[39m\u001b[38;5;241m.\u001b[39mformat(size))\n",
      "\u001b[0;31mValueError\u001b[0m: Expected more than 1 value per channel when training, got input size torch.Size([1, 1282])"
     ]
    }
   ],
   "source": [
    "model.train()\n",
    "final_loss=0\n",
    "\n",
    "for x, y in train_dl:\n",
    "    x, y = x.to(device), y.to(device)\n",
    "\n",
    "    # Compute prediction error\n",
    "    pred = model(x)\n",
    "    loss = loss_fn(pred, y)\n",
    "\n",
    "    # Backpropagation\n",
    "    optimizer.zero_grad()\n",
    "    loss.backward()\n",
    "    optimizer.step()\n",
    "    scheduler.step()\n",
    "\n",
    "    final_loss += loss.item()\n",
    "\n",
    "final_loss /= len(dl)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 49,
   "metadata": {},
   "outputs": [],
   "source": [
    "train_dl = DataLoader(train_ds,bs=8,shuffle=True,num_workers=4,drop_last=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 50,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "0.8554554958647924"
      ]
     },
     "execution_count": 50,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "train_fn(train_dl,model,loss_fn, optimizer,scheduler)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 45,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Epoch 1\n",
      "-------------------------------\n"
     ]
    },
    {
     "ename": "ValueError",
     "evalue": "Expected more than 1 value per channel when training, got input size torch.Size([1, 1282])",
     "output_type": "error",
     "traceback": [
      "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
      "\u001b[0;31mValueError\u001b[0m                                Traceback (most recent call last)",
      "Input \u001b[0;32mIn [45]\u001b[0m, in \u001b[0;36m<cell line: 6>\u001b[0;34m()\u001b[0m\n\u001b[1;32m     24\u001b[0m \u001b[38;5;28;01mfor\u001b[39;00m epoch \u001b[38;5;129;01min\u001b[39;00m \u001b[38;5;28mrange\u001b[39m(\u001b[38;5;241m10\u001b[39m):\n\u001b[1;32m     25\u001b[0m     \u001b[38;5;28mprint\u001b[39m(\u001b[38;5;124mf\u001b[39m\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mEpoch \u001b[39m\u001b[38;5;132;01m{\u001b[39;00mepoch\u001b[38;5;241m+\u001b[39m\u001b[38;5;241m1\u001b[39m\u001b[38;5;132;01m}\u001b[39;00m\u001b[38;5;130;01m\\n\u001b[39;00m\u001b[38;5;124m-------------------------------\u001b[39m\u001b[38;5;124m\"\u001b[39m)\n\u001b[0;32m---> 26\u001b[0m     train_loss \u001b[38;5;241m=\u001b[39m \u001b[43mtrain_fn\u001b[49m\u001b[43m(\u001b[49m\u001b[43mtrain_dl\u001b[49m\u001b[43m,\u001b[49m\u001b[43mmodel\u001b[49m\u001b[43m,\u001b[49m\u001b[43mloss_fn\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43moptimizer\u001b[49m\u001b[43m,\u001b[49m\u001b[43mscheduler\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m     27\u001b[0m     valid_loss,valid_preds \u001b[38;5;241m=\u001b[39m valid_fn(valid_dl,model,loss_fn)\n\u001b[1;32m     28\u001b[0m     \u001b[38;5;66;03m# spearman = stats.spearmanr(valid_preds, valid_ds.y)\u001b[39;00m\n",
      "Input \u001b[0;32mIn [37]\u001b[0m, in \u001b[0;36mtrain_fn\u001b[0;34m(dl, model, loss_fn, optimizer, scheduler)\u001b[0m\n\u001b[1;32m      7\u001b[0m x, y \u001b[38;5;241m=\u001b[39m x\u001b[38;5;241m.\u001b[39mto(device), y\u001b[38;5;241m.\u001b[39mto(device)\n\u001b[1;32m      9\u001b[0m \u001b[38;5;66;03m# Compute prediction error\u001b[39;00m\n\u001b[0;32m---> 10\u001b[0m pred \u001b[38;5;241m=\u001b[39m \u001b[43mmodel\u001b[49m\u001b[43m(\u001b[49m\u001b[43mx\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m     11\u001b[0m loss \u001b[38;5;241m=\u001b[39m loss_fn(pred, y)\n\u001b[1;32m     13\u001b[0m \u001b[38;5;66;03m# Backpropagation\u001b[39;00m\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/module.py:1130\u001b[0m, in \u001b[0;36mModule._call_impl\u001b[0;34m(self, *input, **kwargs)\u001b[0m\n\u001b[1;32m   1126\u001b[0m \u001b[38;5;66;03m# If we don't have any hooks, we want to skip the rest of the logic in\u001b[39;00m\n\u001b[1;32m   1127\u001b[0m \u001b[38;5;66;03m# this function, and just call forward.\u001b[39;00m\n\u001b[1;32m   1128\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_backward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_pre_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_backward_hooks\n\u001b[1;32m   1129\u001b[0m         \u001b[38;5;129;01mor\u001b[39;00m _global_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_forward_pre_hooks):\n\u001b[0;32m-> 1130\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mforward_call\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   1131\u001b[0m \u001b[38;5;66;03m# Do not call functions when jit is used\u001b[39;00m\n\u001b[1;32m   1132\u001b[0m full_backward_hooks, non_full_backward_hooks \u001b[38;5;241m=\u001b[39m [], []\n",
      "Input \u001b[0;32mIn [22]\u001b[0m, in \u001b[0;36mModel2.forward\u001b[0;34m(self, x)\u001b[0m\n\u001b[1;32m     48\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21mforward\u001b[39m(\u001b[38;5;28mself\u001b[39m, x):\n\u001b[0;32m---> 50\u001b[0m     x \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbatch_norm1\u001b[49m\u001b[43m(\u001b[49m\u001b[43mx\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m     51\u001b[0m     x \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mdropout1(x)\n\u001b[1;32m     52\u001b[0m     x \u001b[38;5;241m=\u001b[39m F\u001b[38;5;241m.\u001b[39mcelu(\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mdense1(x), alpha\u001b[38;5;241m=\u001b[39m\u001b[38;5;241m0.06\u001b[39m)\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/module.py:1130\u001b[0m, in \u001b[0;36mModule._call_impl\u001b[0;34m(self, *input, **kwargs)\u001b[0m\n\u001b[1;32m   1126\u001b[0m \u001b[38;5;66;03m# If we don't have any hooks, we want to skip the rest of the logic in\u001b[39;00m\n\u001b[1;32m   1127\u001b[0m \u001b[38;5;66;03m# this function, and just call forward.\u001b[39;00m\n\u001b[1;32m   1128\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_backward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_forward_pre_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_backward_hooks\n\u001b[1;32m   1129\u001b[0m         \u001b[38;5;129;01mor\u001b[39;00m _global_forward_hooks \u001b[38;5;129;01mor\u001b[39;00m _global_forward_pre_hooks):\n\u001b[0;32m-> 1130\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mforward_call\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   1131\u001b[0m \u001b[38;5;66;03m# Do not call functions when jit is used\u001b[39;00m\n\u001b[1;32m   1132\u001b[0m full_backward_hooks, non_full_backward_hooks \u001b[38;5;241m=\u001b[39m [], []\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/modules/batchnorm.py:168\u001b[0m, in \u001b[0;36m_BatchNorm.forward\u001b[0;34m(self, input)\u001b[0m\n\u001b[1;32m    161\u001b[0m     bn_training \u001b[38;5;241m=\u001b[39m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mrunning_mean \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m) \u001b[38;5;129;01mand\u001b[39;00m (\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mrunning_var \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m)\n\u001b[1;32m    163\u001b[0m \u001b[38;5;124mr\u001b[39m\u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[1;32m    164\u001b[0m \u001b[38;5;124;03mBuffers are only updated if they are to be tracked and we are in training mode. Thus they only need to be\u001b[39;00m\n\u001b[1;32m    165\u001b[0m \u001b[38;5;124;03mpassed when the update should occur (i.e. in training mode when they are tracked), or when buffer stats are\u001b[39;00m\n\u001b[1;32m    166\u001b[0m \u001b[38;5;124;03mused for normalization (i.e. in eval mode when buffers are not None).\u001b[39;00m\n\u001b[1;32m    167\u001b[0m \u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[0;32m--> 168\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mF\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbatch_norm\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m    169\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[43m,\u001b[49m\n\u001b[1;32m    170\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;66;43;03m# If buffers are not to be tracked, ensure that they won't be updated\u001b[39;49;00m\n\u001b[1;32m    171\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrunning_mean\u001b[49m\n\u001b[1;32m    172\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43;01mif\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mnot\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtraining\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mor\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtrack_running_stats\u001b[49m\n\u001b[1;32m    173\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43;01melse\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mNone\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m    174\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrunning_var\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mif\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mnot\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtraining\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;129;43;01mor\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mtrack_running_stats\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;28;43;01melse\u001b[39;49;00m\u001b[43m \u001b[49m\u001b[38;5;28;43;01mNone\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m    175\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mweight\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    176\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbias\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    177\u001b[0m \u001b[43m    \u001b[49m\u001b[43mbn_training\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    178\u001b[0m \u001b[43m    \u001b[49m\u001b[43mexponential_average_factor\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    179\u001b[0m \u001b[43m    \u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43meps\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m    180\u001b[0m \u001b[43m\u001b[49m\u001b[43m)\u001b[49m\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/functional.py:2436\u001b[0m, in \u001b[0;36mbatch_norm\u001b[0;34m(input, running_mean, running_var, weight, bias, training, momentum, eps)\u001b[0m\n\u001b[1;32m   2423\u001b[0m     \u001b[38;5;28;01mreturn\u001b[39;00m handle_torch_function(\n\u001b[1;32m   2424\u001b[0m         batch_norm,\n\u001b[1;32m   2425\u001b[0m         (\u001b[38;5;28minput\u001b[39m, running_mean, running_var, weight, bias),\n\u001b[0;32m   (...)\u001b[0m\n\u001b[1;32m   2433\u001b[0m         eps\u001b[38;5;241m=\u001b[39meps,\n\u001b[1;32m   2434\u001b[0m     )\n\u001b[1;32m   2435\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m training:\n\u001b[0;32m-> 2436\u001b[0m     \u001b[43m_verify_batch_size\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;28;43minput\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43msize\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m   2438\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m torch\u001b[38;5;241m.\u001b[39mbatch_norm(\n\u001b[1;32m   2439\u001b[0m     \u001b[38;5;28minput\u001b[39m, weight, bias, running_mean, running_var, training, momentum, eps, torch\u001b[38;5;241m.\u001b[39mbackends\u001b[38;5;241m.\u001b[39mcudnn\u001b[38;5;241m.\u001b[39menabled\n\u001b[1;32m   2440\u001b[0m )\n",
      "File \u001b[0;32m/usr/local/lib/python3.9/dist-packages/torch/nn/functional.py:2404\u001b[0m, in \u001b[0;36m_verify_batch_size\u001b[0;34m(size)\u001b[0m\n\u001b[1;32m   2402\u001b[0m     size_prods \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m=\u001b[39m size[i \u001b[38;5;241m+\u001b[39m \u001b[38;5;241m2\u001b[39m]\n\u001b[1;32m   2403\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m size_prods \u001b[38;5;241m==\u001b[39m \u001b[38;5;241m1\u001b[39m:\n\u001b[0;32m-> 2404\u001b[0m     \u001b[38;5;28;01mraise\u001b[39;00m \u001b[38;5;167;01mValueError\u001b[39;00m(\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mExpected more than 1 value per channel when training, got input size \u001b[39m\u001b[38;5;132;01m{}\u001b[39;00m\u001b[38;5;124m\"\u001b[39m\u001b[38;5;241m.\u001b[39mformat(size))\n",
      "\u001b[0;31mValueError\u001b[0m: Expected more than 1 value per channel when training, got input size torch.Size([1, 1282])"
     ]
    }
   ],
   "source": [
    "seed_everything(2)\n",
    "\n",
    "test_preds = np.zeros((len(test_df), 1))\n",
    "oofs = np.zeros((len(df), 1))\n",
    "\n",
    "for fold, (train_idx, valid_idx) in enumerate(GroupKFold(2).split(df, groups=df.group)):\n",
    "    train_df = df.iloc[train_idx]\n",
    "    valid_df = df.iloc[valid_idx]\n",
    "\n",
    "    train_ds = MyDataset(train_df,features,'y_normalize')\n",
    "    valid_ds = MyDataset(valid_df,features,'y_normalize')\n",
    "\n",
    "    train_dl = DataLoader(train_ds,bs=8,shuffle=True,num_workers=4,drop_last=True)\n",
    "    valid_dl = DataLoader(valid_ds,bs=8,shuffle=False,num_workers=4)\n",
    "\n",
    "    oof = np.zeros((len(df), 1))\n",
    "    best_loss = np.inf\n",
    "\n",
    "    model = Model2(num_features,num_targets,hidden_size).cuda()\n",
    "    loss_fn = MSELossFlat()\n",
    "    optimizer = torch.optim.Adam(model.parameters(), lr=1e-3, weight_decay=1e-5)\n",
    "    scheduler = OneCycleLR(optimizer, max_lr=1e-2,steps_per_epoch=len(train_dl),div_factor=1e3, epochs=25,pct_start=0.1)\n",
    "\n",
    "    for epoch in range(10):\n",
    "        print(f\"Epoch {epoch+1}\\n-------------------------------\")\n",
    "        train_loss = train_fn(train_dl,model,loss_fn, optimizer,scheduler)\n",
    "        valid_loss,valid_preds = valid_fn(valid_dl,model,loss_fn)\n",
    "        # spearman = stats.spearmanr(valid_preds, valid_ds.y)\n",
    "        print(f'In fold{fold} epoch{epoch}, train loss:{train_loss}, valid loss:{valid_loss},spearman:{spearman}')\n",
    "\n",
    "        if valid_loss < best_loss:\n",
    "            best_loss = valid_loss\n",
    "            oof[valid_idx] = valid_preds\n",
    "            torch.save(model.state_dict(),f'my_model/fold{fold}.pth')\n",
    "\n",
    "\n",
    "    test_ds = TestDataset(test_df,features)\n",
    "    test_dl = DataLoader(test_ds,bs=8,shuffle=False,num_workers=4)\n",
    "\n",
    "    model = Model2(num_features,num_targets,hidden_size)\n",
    "    model.load_state_dict(torch.load(f'my_model/fold{fold}.pth'))\n",
    "    model.to(device)\n",
    "\n",
    "    oofs+=oof/2\n",
    "\n",
    "    test_preds += test_fn(test_dl,model)/2"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 144,
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "      <th>45</th>\n",
       "      <th>46</th>\n",
       "      <th>47</th>\n",
       "      <th>48</th>\n",
       "      <th>49</th>\n",
       "      <th>50</th>\n",
       "      <th>51</th>\n",
       "      <th>52</th>\n",
       "      <th>53</th>\n",
       "      <th>54</th>\n",
       "      <th>55</th>\n",
       "      <th>56</th>\n",
       "      <th>57</th>\n",
       "      <th>58</th>\n",
       "      <th>59</th>\n",
       "      <th>60</th>\n",
       "      <th>61</th>\n",
       "      <th>62</th>\n",
       "      <th>63</th>\n",
       "      <th>64</th>\n",
       "      <th>65</th>\n",
       "      <th>66</th>\n",
       "      <th>67</th>\n",
       "      <th>68</th>\n",
       "      <th>69</th>\n",
       "      <th>70</th>\n",
       "      <th>71</th>\n",
       "      <th>72</th>\n",
       "      <th>73</th>\n",
       "      <th>74</th>\n",
       "      <th>75</th>\n",
       "      <th>76</th>\n",
       "      <th>77</th>\n",
       "      <th>78</th>\n",
       "      <th>79</th>\n",
       "      <th>80</th>\n",
       "      <th>81</th>\n",
       "      <th>82</th>\n",
       "      <th>83</th>\n",
       "      <th>84</th>\n",
       "      <th>85</th>\n",
       "      <th>86</th>\n",
       "      <th>87</th>\n",
       "      <th>88</th>\n",
       "      <th>89</th>\n",
       "      <th>90</th>\n",
       "      <th>91</th>\n",
       "      <th>92</th>\n",
       "      <th>93</th>\n",
       "      <th>94</th>\n",
       "      <th>95</th>\n",
       "      <th>96</th>\n",
       "      <th>97</th>\n",
       "      <th>98</th>\n",
       "      <th>99</th>\n",
       "      <th>100</th>\n",
       "      <th>101</th>\n",
       "      <th>102</th>\n",
       "      <th>103</th>\n",
       "      <th>104</th>\n",
       "      <th>105</th>\n",
       "      <th>106</th>\n",
       "      <th>107</th>\n",
       "      <th>108</th>\n",
       "      <th>109</th>\n",
       "      <th>110</th>\n",
       "      <th>111</th>\n",
       "      <th>112</th>\n",
       "      <th>113</th>\n",
       "      <th>114</th>\n",
       "      <th>115</th>\n",
       "      <th>116</th>\n",
       "      <th>117</th>\n",
       "      <th>118</th>\n",
       "      <th>119</th>\n",
       "      <th>120</th>\n",
       "      <th>121</th>\n",
       "      <th>122</th>\n",
       "      <th>123</th>\n",
       "      <th>124</th>\n",
       "      <th>125</th>\n",
       "      <th>126</th>\n",
       "      <th>127</th>\n",
       "      <th>128</th>\n",
       "      <th>129</th>\n",
       "      <th>130</th>\n",
       "      <th>131</th>\n",
       "      <th>132</th>\n",
       "      <th>133</th>\n",
       "      <th>134</th>\n",
       "      <th>135</th>\n",
       "      <th>136</th>\n",
       "      <th>137</th>\n",
       "      <th>138</th>\n",
       "      <th>139</th>\n",
       "      <th>140</th>\n",
       "      <th>141</th>\n",
       "      <th>142</th>\n",
       "      <th>143</th>\n",
       "      <th>144</th>\n",
       "      <th>145</th>\n",
       "      <th>146</th>\n",
       "      <th>147</th>\n",
       "      <th>148</th>\n",
       "      <th>149</th>\n",
       "      <th>150</th>\n",
       "      <th>151</th>\n",
       "      <th>152</th>\n",
       "      <th>153</th>\n",
       "      <th>154</th>\n",
       "      <th>155</th>\n",
       "      <th>156</th>\n",
       "      <th>157</th>\n",
       "      <th>158</th>\n",
       "      <th>159</th>\n",
       "      <th>160</th>\n",
       "      <th>161</th>\n",
       "      <th>162</th>\n",
       "      <th>163</th>\n",
       "      <th>164</th>\n",
       "      <th>165</th>\n",
       "      <th>166</th>\n",
       "      <th>167</th>\n",
       "      <th>168</th>\n",
       "      <th>169</th>\n",
       "      <th>170</th>\n",
       "      <th>171</th>\n",
       "      <th>172</th>\n",
       "      <th>173</th>\n",
       "      <th>174</th>\n",
       "      <th>175</th>\n",
       "      <th>176</th>\n",
       "      <th>177</th>\n",
       "      <th>178</th>\n",
       "      <th>179</th>\n",
       "      <th>180</th>\n",
       "      <th>181</th>\n",
       "      <th>182</th>\n",
       "      <th>183</th>\n",
       "      <th>184</th>\n",
       "      <th>185</th>\n",
       "      <th>186</th>\n",
       "      <th>187</th>\n",
       "      <th>188</th>\n",
       "      <th>189</th>\n",
       "      <th>190</th>\n",
       "      <th>191</th>\n",
       "      <th>192</th>\n",
       "      <th>193</th>\n",
       "      <th>194</th>\n",
       "      <th>195</th>\n",
       "      <th>196</th>\n",
       "      <th>197</th>\n",
       "      <th>198</th>\n",
       "      <th>199</th>\n",
       "      <th>200</th>\n",
       "      <th>201</th>\n",
       "      <th>202</th>\n",
       "      <th>203</th>\n",
       "      <th>204</th>\n",
       "      <th>205</th>\n",
       "      <th>206</th>\n",
       "      <th>207</th>\n",
       "      <th>208</th>\n",
       "      <th>209</th>\n",
       "      <th>210</th>\n",
       "      <th>211</th>\n",
       "      <th>212</th>\n",
       "      <th>213</th>\n",
       "      <th>214</th>\n",
       "      <th>215</th>\n",
       "      <th>216</th>\n",
       "      <th>217</th>\n",
       "      <th>218</th>\n",
       "      <th>219</th>\n",
       "      <th>220</th>\n",
       "      <th>221</th>\n",
       "      <th>222</th>\n",
       "      <th>223</th>\n",
       "      <th>224</th>\n",
       "      <th>225</th>\n",
       "      <th>226</th>\n",
       "      <th>227</th>\n",
       "      <th>228</th>\n",
       "      <th>229</th>\n",
       "      <th>230</th>\n",
       "      <th>231</th>\n",
       "      <th>232</th>\n",
       "      <th>233</th>\n",
       "      <th>234</th>\n",
       "      <th>235</th>\n",
       "      <th>236</th>\n",
       "      <th>237</th>\n",
       "      <th>238</th>\n",
       "      <th>239</th>\n",
       "      <th>240</th>\n",
       "      <th>241</th>\n",
       "      <th>242</th>\n",
       "      <th>243</th>\n",
       "      <th>244</th>\n",
       "      <th>245</th>\n",
       "      <th>246</th>\n",
       "      <th>247</th>\n",
       "      <th>248</th>\n",
       "      <th>249</th>\n",
       "      <th>250</th>\n",
       "      <th>251</th>\n",
       "      <th>252</th>\n",
       "      <th>253</th>\n",
       "      <th>254</th>\n",
       "      <th>255</th>\n",
       "      <th>256</th>\n",
       "      <th>257</th>\n",
       "      <th>258</th>\n",
       "      <th>259</th>\n",
       "      <th>260</th>\n",
       "      <th>261</th>\n",
       "      <th>262</th>\n",
       "      <th>263</th>\n",
       "      <th>264</th>\n",
       "      <th>265</th>\n",
       "      <th>266</th>\n",
       "      <th>267</th>\n",
       "      <th>268</th>\n",
       "      <th>269</th>\n",
       "      <th>270</th>\n",
       "      <th>271</th>\n",
       "      <th>272</th>\n",
       "      <th>273</th>\n",
       "      <th>274</th>\n",
       "      <th>275</th>\n",
       "      <th>276</th>\n",
       "      <th>277</th>\n",
       "      <th>278</th>\n",
       "      <th>279</th>\n",
       "      <th>280</th>\n",
       "      <th>281</th>\n",
       "      <th>282</th>\n",
       "      <th>283</th>\n",
       "      <th>284</th>\n",
       "      <th>285</th>\n",
       "      <th>286</th>\n",
       "      <th>287</th>\n",
       "      <th>288</th>\n",
       "      <th>289</th>\n",
       "      <th>290</th>\n",
       "      <th>291</th>\n",
       "      <th>292</th>\n",
       "      <th>293</th>\n",
       "      <th>294</th>\n",
       "      <th>295</th>\n",
       "      <th>296</th>\n",
       "      <th>297</th>\n",
       "      <th>298</th>\n",
       "      <th>299</th>\n",
       "      <th>300</th>\n",
       "      <th>301</th>\n",
       "      <th>302</th>\n",
       "      <th>303</th>\n",
       "      <th>304</th>\n",
       "      <th>305</th>\n",
       "      <th>306</th>\n",
       "      <th>307</th>\n",
       "      <th>308</th>\n",
       "      <th>309</th>\n",
       "      <th>310</th>\n",
       "      <th>311</th>\n",
       "      <th>312</th>\n",
       "      <th>313</th>\n",
       "      <th>314</th>\n",
       "      <th>315</th>\n",
       "      <th>316</th>\n",
       "      <th>317</th>\n",
       "      <th>318</th>\n",
       "      <th>319</th>\n",
       "      <th>320</th>\n",
       "      <th>321</th>\n",
       "      <th>322</th>\n",
       "      <th>323</th>\n",
       "      <th>324</th>\n",
       "      <th>325</th>\n",
       "      <th>326</th>\n",
       "      <th>327</th>\n",
       "      <th>328</th>\n",
       "      <th>329</th>\n",
       "      <th>330</th>\n",
       "      <th>331</th>\n",
       "      <th>332</th>\n",
       "      <th>333</th>\n",
       "      <th>334</th>\n",
       "      <th>335</th>\n",
       "      <th>336</th>\n",
       "      <th>337</th>\n",
       "      <th>338</th>\n",
       "      <th>339</th>\n",
       "      <th>340</th>\n",
       "      <th>341</th>\n",
       "      <th>342</th>\n",
       "      <th>343</th>\n",
       "      <th>344</th>\n",
       "      <th>345</th>\n",
       "      <th>346</th>\n",
       "      <th>347</th>\n",
       "      <th>348</th>\n",
       "      <th>349</th>\n",
       "      <th>350</th>\n",
       "      <th>351</th>\n",
       "      <th>352</th>\n",
       "      <th>353</th>\n",
       "      <th>354</th>\n",
       "      <th>355</th>\n",
       "      <th>356</th>\n",
       "      <th>357</th>\n",
       "      <th>358</th>\n",
       "      <th>359</th>\n",
       "      <th>360</th>\n",
       "      <th>361</th>\n",
       "      <th>362</th>\n",
       "      <th>363</th>\n",
       "      <th>364</th>\n",
       "      <th>365</th>\n",
       "      <th>366</th>\n",
       "      <th>367</th>\n",
       "      <th>368</th>\n",
       "      <th>369</th>\n",
       "      <th>370</th>\n",
       "      <th>371</th>\n",
       "      <th>372</th>\n",
       "      <th>373</th>\n",
       "      <th>374</th>\n",
       "      <th>375</th>\n",
       "      <th>376</th>\n",
       "      <th>377</th>\n",
       "      <th>378</th>\n",
       "      <th>379</th>\n",
       "      <th>380</th>\n",
       "      <th>381</th>\n",
       "      <th>382</th>\n",
       "      <th>383</th>\n",
       "      <th>384</th>\n",
       "      <th>385</th>\n",
       "      <th>386</th>\n",
       "      <th>387</th>\n",
       "      <th>388</th>\n",
       "      <th>389</th>\n",
       "      <th>390</th>\n",
       "      <th>391</th>\n",
       "      <th>392</th>\n",
       "      <th>393</th>\n",
       "      <th>394</th>\n",
       "      <th>395</th>\n",
       "      <th>396</th>\n",
       "      <th>397</th>\n",
       "      <th>398</th>\n",
       "      <th>399</th>\n",
       "      <th>400</th>\n",
       "      <th>401</th>\n",
       "      <th>402</th>\n",
       "      <th>403</th>\n",
       "      <th>404</th>\n",
       "      <th>405</th>\n",
       "      <th>406</th>\n",
       "      <th>407</th>\n",
       "      <th>408</th>\n",
       "      <th>409</th>\n",
       "      <th>410</th>\n",
       "      <th>411</th>\n",
       "      <th>412</th>\n",
       "      <th>413</th>\n",
       "      <th>414</th>\n",
       "      <th>415</th>\n",
       "      <th>416</th>\n",
       "      <th>417</th>\n",
       "      <th>418</th>\n",
       "      <th>419</th>\n",
       "      <th>420</th>\n",
       "      <th>421</th>\n",
       "      <th>422</th>\n",
       "      <th>423</th>\n",
       "      <th>424</th>\n",
       "      <th>425</th>\n",
       "      <th>426</th>\n",
       "      <th>427</th>\n",
       "      <th>428</th>\n",
       "      <th>429</th>\n",
       "      <th>430</th>\n",
       "      <th>431</th>\n",
       "      <th>432</th>\n",
       "      <th>433</th>\n",
       "      <th>434</th>\n",
       "      <th>435</th>\n",
       "      <th>436</th>\n",
       "      <th>437</th>\n",
       "      <th>438</th>\n",
       "      <th>439</th>\n",
       "      <th>440</th>\n",
       "      <th>441</th>\n",
       "      <th>442</th>\n",
       "      <th>443</th>\n",
       "      <th>444</th>\n",
       "      <th>445</th>\n",
       "      <th>446</th>\n",
       "      <th>447</th>\n",
       "      <th>448</th>\n",
       "      <th>449</th>\n",
       "      <th>450</th>\n",
       "      <th>451</th>\n",
       "      <th>452</th>\n",
       "      <th>453</th>\n",
       "      <th>454</th>\n",
       "      <th>455</th>\n",
       "      <th>456</th>\n",
       "      <th>457</th>\n",
       "      <th>458</th>\n",
       "      <th>459</th>\n",
       "      <th>460</th>\n",
       "      <th>461</th>\n",
       "      <th>462</th>\n",
       "      <th>463</th>\n",
       "      <th>464</th>\n",
       "      <th>465</th>\n",
       "      <th>466</th>\n",
       "      <th>467</th>\n",
       "      <th>468</th>\n",
       "      <th>469</th>\n",
       "      <th>470</th>\n",
       "      <th>471</th>\n",
       "      <th>472</th>\n",
       "      <th>473</th>\n",
       "      <th>474</th>\n",
       "      <th>475</th>\n",
       "      <th>476</th>\n",
       "      <th>477</th>\n",
       "      <th>478</th>\n",
       "      <th>479</th>\n",
       "      <th>480</th>\n",
       "      <th>481</th>\n",
       "      <th>482</th>\n",
       "      <th>483</th>\n",
       "      <th>484</th>\n",
       "      <th>485</th>\n",
       "      <th>486</th>\n",
       "      <th>487</th>\n",
       "      <th>488</th>\n",
       "      <th>489</th>\n",
       "      <th>490</th>\n",
       "      <th>491</th>\n",
       "      <th>492</th>\n",
       "      <th>493</th>\n",
       "      <th>494</th>\n",
       "      <th>495</th>\n",
       "      <th>496</th>\n",
       "      <th>497</th>\n",
       "      <th>498</th>\n",
       "      <th>...</th>\n",
       "      <th>783</th>\n",
       "      <th>784</th>\n",
       "      <th>785</th>\n",
       "      <th>786</th>\n",
       "      <th>787</th>\n",
       "      <th>788</th>\n",
       "      <th>789</th>\n",
       "      <th>790</th>\n",
       "      <th>791</th>\n",
       "      <th>792</th>\n",
       "      <th>793</th>\n",
       "      <th>794</th>\n",
       "      <th>795</th>\n",
       "      <th>796</th>\n",
       "      <th>797</th>\n",
       "      <th>798</th>\n",
       "      <th>799</th>\n",
       "      <th>800</th>\n",
       "      <th>801</th>\n",
       "      <th>802</th>\n",
       "      <th>803</th>\n",
       "      <th>804</th>\n",
       "      <th>805</th>\n",
       "      <th>806</th>\n",
       "      <th>807</th>\n",
       "      <th>808</th>\n",
       "      <th>809</th>\n",
       "      <th>810</th>\n",
       "      <th>811</th>\n",
       "      <th>812</th>\n",
       "      <th>813</th>\n",
       "      <th>814</th>\n",
       "      <th>815</th>\n",
       "      <th>816</th>\n",
       "      <th>817</th>\n",
       "      <th>818</th>\n",
       "      <th>819</th>\n",
       "      <th>820</th>\n",
       "      <th>821</th>\n",
       "      <th>822</th>\n",
       "      <th>823</th>\n",
       "      <th>824</th>\n",
       "      <th>825</th>\n",
       "      <th>826</th>\n",
       "      <th>827</th>\n",
       "      <th>828</th>\n",
       "      <th>829</th>\n",
       "      <th>830</th>\n",
       "      <th>831</th>\n",
       "      <th>832</th>\n",
       "      <th>833</th>\n",
       "      <th>834</th>\n",
       "      <th>835</th>\n",
       "      <th>836</th>\n",
       "      <th>837</th>\n",
       "      <th>838</th>\n",
       "      <th>839</th>\n",
       "      <th>840</th>\n",
       "      <th>841</th>\n",
       "      <th>842</th>\n",
       "      <th>843</th>\n",
       "      <th>844</th>\n",
       "      <th>845</th>\n",
       "      <th>846</th>\n",
       "      <th>847</th>\n",
       "      <th>848</th>\n",
       "      <th>849</th>\n",
       "      <th>850</th>\n",
       "      <th>851</th>\n",
       "      <th>852</th>\n",
       "      <th>853</th>\n",
       "      <th>854</th>\n",
       "      <th>855</th>\n",
       "      <th>856</th>\n",
       "      <th>857</th>\n",
       "      <th>858</th>\n",
       "      <th>859</th>\n",
       "      <th>860</th>\n",
       "      <th>861</th>\n",
       "      <th>862</th>\n",
       "      <th>863</th>\n",
       "      <th>864</th>\n",
       "      <th>865</th>\n",
       "      <th>866</th>\n",
       "      <th>867</th>\n",
       "      <th>868</th>\n",
       "      <th>869</th>\n",
       "      <th>870</th>\n",
       "      <th>871</th>\n",
       "      <th>872</th>\n",
       "      <th>873</th>\n",
       "      <th>874</th>\n",
       "      <th>875</th>\n",
       "      <th>876</th>\n",
       "      <th>877</th>\n",
       "      <th>878</th>\n",
       "      <th>879</th>\n",
       "      <th>880</th>\n",
       "      <th>881</th>\n",
       "      <th>882</th>\n",
       "      <th>883</th>\n",
       "      <th>884</th>\n",
       "      <th>885</th>\n",
       "      <th>886</th>\n",
       "      <th>887</th>\n",
       "      <th>888</th>\n",
       "      <th>889</th>\n",
       "      <th>890</th>\n",
       "      <th>891</th>\n",
       "      <th>892</th>\n",
       "      <th>893</th>\n",
       "      <th>894</th>\n",
       "      <th>895</th>\n",
       "      <th>896</th>\n",
       "      <th>897</th>\n",
       "      <th>898</th>\n",
       "      <th>899</th>\n",
       "      <th>900</th>\n",
       "      <th>901</th>\n",
       "      <th>902</th>\n",
       "      <th>903</th>\n",
       "      <th>904</th>\n",
       "      <th>905</th>\n",
       "      <th>906</th>\n",
       "      <th>907</th>\n",
       "      <th>908</th>\n",
       "      <th>909</th>\n",
       "      <th>910</th>\n",
       "      <th>911</th>\n",
       "      <th>912</th>\n",
       "      <th>913</th>\n",
       "      <th>914</th>\n",
       "      <th>915</th>\n",
       "      <th>916</th>\n",
       "      <th>917</th>\n",
       "      <th>918</th>\n",
       "      <th>919</th>\n",
       "      <th>920</th>\n",
       "      <th>921</th>\n",
       "      <th>922</th>\n",
       "      <th>923</th>\n",
       "      <th>924</th>\n",
       "      <th>925</th>\n",
       "      <th>926</th>\n",
       "      <th>927</th>\n",
       "      <th>928</th>\n",
       "      <th>929</th>\n",
       "      <th>930</th>\n",
       "      <th>931</th>\n",
       "      <th>932</th>\n",
       "      <th>933</th>\n",
       "      <th>934</th>\n",
       "      <th>935</th>\n",
       "      <th>936</th>\n",
       "      <th>937</th>\n",
       "      <th>938</th>\n",
       "      <th>939</th>\n",
       "      <th>940</th>\n",
       "      <th>941</th>\n",
       "      <th>942</th>\n",
       "      <th>943</th>\n",
       "      <th>944</th>\n",
       "      <th>945</th>\n",
       "      <th>946</th>\n",
       "      <th>947</th>\n",
       "      <th>948</th>\n",
       "      <th>949</th>\n",
       "      <th>950</th>\n",
       "      <th>951</th>\n",
       "      <th>952</th>\n",
       "      <th>953</th>\n",
       "      <th>954</th>\n",
       "      <th>955</th>\n",
       "      <th>956</th>\n",
       "      <th>957</th>\n",
       "      <th>958</th>\n",
       "      <th>959</th>\n",
       "      <th>960</th>\n",
       "      <th>961</th>\n",
       "      <th>962</th>\n",
       "      <th>963</th>\n",
       "      <th>964</th>\n",
       "      <th>965</th>\n",
       "      <th>966</th>\n",
       "      <th>967</th>\n",
       "      <th>968</th>\n",
       "      <th>969</th>\n",
       "      <th>970</th>\n",
       "      <th>971</th>\n",
       "      <th>972</th>\n",
       "      <th>973</th>\n",
       "      <th>974</th>\n",
       "      <th>975</th>\n",
       "      <th>976</th>\n",
       "      <th>977</th>\n",
       "      <th>978</th>\n",
       "      <th>979</th>\n",
       "      <th>980</th>\n",
       "      <th>981</th>\n",
       "      <th>982</th>\n",
       "      <th>983</th>\n",
       "      <th>984</th>\n",
       "      <th>985</th>\n",
       "      <th>986</th>\n",
       "      <th>987</th>\n",
       "      <th>988</th>\n",
       "      <th>989</th>\n",
       "      <th>990</th>\n",
       "      <th>991</th>\n",
       "      <th>992</th>\n",
       "      <th>993</th>\n",
       "      <th>994</th>\n",
       "      <th>995</th>\n",
       "      <th>996</th>\n",
       "      <th>997</th>\n",
       "      <th>998</th>\n",
       "      <th>999</th>\n",
       "      <th>1000</th>\n",
       "      <th>1001</th>\n",
       "      <th>1002</th>\n",
       "      <th>1003</th>\n",
       "      <th>1004</th>\n",
       "      <th>1005</th>\n",
       "      <th>1006</th>\n",
       "      <th>1007</th>\n",
       "      <th>1008</th>\n",
       "      <th>1009</th>\n",
       "      <th>1010</th>\n",
       "      <th>1011</th>\n",
       "      <th>1012</th>\n",
       "      <th>1013</th>\n",
       "      <th>1014</th>\n",
       "      <th>1015</th>\n",
       "      <th>1016</th>\n",
       "      <th>1017</th>\n",
       "      <th>1018</th>\n",
       "      <th>1019</th>\n",
       "      <th>1020</th>\n",
       "      <th>1021</th>\n",
       "      <th>1022</th>\n",
       "      <th>1023</th>\n",
       "      <th>1024</th>\n",
       "      <th>1025</th>\n",
       "      <th>1026</th>\n",
       "      <th>1027</th>\n",
       "      <th>1028</th>\n",
       "      <th>1029</th>\n",
       "      <th>1030</th>\n",
       "      <th>1031</th>\n",
       "      <th>1032</th>\n",
       "      <th>1033</th>\n",
       "      <th>1034</th>\n",
       "      <th>1035</th>\n",
       "      <th>1036</th>\n",
       "      <th>1037</th>\n",
       "      <th>1038</th>\n",
       "      <th>1039</th>\n",
       "      <th>1040</th>\n",
       "      <th>1041</th>\n",
       "      <th>1042</th>\n",
       "      <th>1043</th>\n",
       "      <th>1044</th>\n",
       "      <th>1045</th>\n",
       "      <th>1046</th>\n",
       "      <th>1047</th>\n",
       "      <th>1048</th>\n",
       "      <th>1049</th>\n",
       "      <th>1050</th>\n",
       "      <th>1051</th>\n",
       "      <th>1052</th>\n",
       "      <th>1053</th>\n",
       "      <th>1054</th>\n",
       "      <th>1055</th>\n",
       "      <th>1056</th>\n",
       "      <th>1057</th>\n",
       "      <th>1058</th>\n",
       "      <th>1059</th>\n",
       "      <th>1060</th>\n",
       "      <th>1061</th>\n",
       "      <th>1062</th>\n",
       "      <th>1063</th>\n",
       "      <th>1064</th>\n",
       "      <th>1065</th>\n",
       "      <th>1066</th>\n",
       "      <th>1067</th>\n",
       "      <th>1068</th>\n",
       "      <th>1069</th>\n",
       "      <th>1070</th>\n",
       "      <th>1071</th>\n",
       "      <th>1072</th>\n",
       "      <th>1073</th>\n",
       "      <th>1074</th>\n",
       "      <th>1075</th>\n",
       "      <th>1076</th>\n",
       "      <th>1077</th>\n",
       "      <th>1078</th>\n",
       "      <th>1079</th>\n",
       "      <th>1080</th>\n",
       "      <th>1081</th>\n",
       "      <th>1082</th>\n",
       "      <th>1083</th>\n",
       "      <th>1084</th>\n",
       "      <th>1085</th>\n",
       "      <th>1086</th>\n",
       "      <th>1087</th>\n",
       "      <th>1088</th>\n",
       "      <th>1089</th>\n",
       "      <th>1090</th>\n",
       "      <th>1091</th>\n",
       "      <th>1092</th>\n",
       "      <th>1093</th>\n",
       "      <th>1094</th>\n",
       "      <th>1095</th>\n",
       "      <th>1096</th>\n",
       "      <th>1097</th>\n",
       "      <th>1098</th>\n",
       "      <th>1099</th>\n",
       "      <th>1100</th>\n",
       "      <th>1101</th>\n",
       "      <th>1102</th>\n",
       "      <th>1103</th>\n",
       "      <th>1104</th>\n",
       "      <th>1105</th>\n",
       "      <th>1106</th>\n",
       "      <th>1107</th>\n",
       "      <th>1108</th>\n",
       "      <th>1109</th>\n",
       "      <th>1110</th>\n",
       "      <th>1111</th>\n",
       "      <th>1112</th>\n",
       "      <th>1113</th>\n",
       "      <th>1114</th>\n",
       "      <th>1115</th>\n",
       "      <th>1116</th>\n",
       "      <th>1117</th>\n",
       "      <th>1118</th>\n",
       "      <th>1119</th>\n",
       "      <th>1120</th>\n",
       "      <th>1121</th>\n",
       "      <th>1122</th>\n",
       "      <th>1123</th>\n",
       "      <th>1124</th>\n",
       "      <th>1125</th>\n",
       "      <th>1126</th>\n",
       "      <th>1127</th>\n",
       "      <th>1128</th>\n",
       "      <th>1129</th>\n",
       "      <th>1130</th>\n",
       "      <th>1131</th>\n",
       "      <th>1132</th>\n",
       "      <th>1133</th>\n",
       "      <th>1134</th>\n",
       "      <th>1135</th>\n",
       "      <th>1136</th>\n",
       "      <th>1137</th>\n",
       "      <th>1138</th>\n",
       "      <th>1139</th>\n",
       "      <th>1140</th>\n",
       "      <th>1141</th>\n",
       "      <th>1142</th>\n",
       "      <th>1143</th>\n",
       "      <th>1144</th>\n",
       "      <th>1145</th>\n",
       "      <th>1146</th>\n",
       "      <th>1147</th>\n",
       "      <th>1148</th>\n",
       "      <th>1149</th>\n",
       "      <th>1150</th>\n",
       "      <th>1151</th>\n",
       "      <th>1152</th>\n",
       "      <th>1153</th>\n",
       "      <th>1154</th>\n",
       "      <th>1155</th>\n",
       "      <th>1156</th>\n",
       "      <th>1157</th>\n",
       "      <th>1158</th>\n",
       "      <th>1159</th>\n",
       "      <th>1160</th>\n",
       "      <th>1161</th>\n",
       "      <th>1162</th>\n",
       "      <th>1163</th>\n",
       "      <th>1164</th>\n",
       "      <th>1165</th>\n",
       "      <th>1166</th>\n",
       "      <th>1167</th>\n",
       "      <th>1168</th>\n",
       "      <th>1169</th>\n",
       "      <th>1170</th>\n",
       "      <th>1171</th>\n",
       "      <th>1172</th>\n",
       "      <th>1173</th>\n",
       "      <th>1174</th>\n",
       "      <th>1175</th>\n",
       "      <th>1176</th>\n",
       "      <th>1177</th>\n",
       "      <th>1178</th>\n",
       "      <th>1179</th>\n",
       "      <th>1180</th>\n",
       "      <th>1181</th>\n",
       "      <th>1182</th>\n",
       "      <th>1183</th>\n",
       "      <th>1184</th>\n",
       "      <th>1185</th>\n",
       "      <th>1186</th>\n",
       "      <th>1187</th>\n",
       "      <th>1188</th>\n",
       "      <th>1189</th>\n",
       "      <th>1190</th>\n",
       "      <th>1191</th>\n",
       "      <th>1192</th>\n",
       "      <th>1193</th>\n",
       "      <th>1194</th>\n",
       "      <th>1195</th>\n",
       "      <th>1196</th>\n",
       "      <th>1197</th>\n",
       "      <th>1198</th>\n",
       "      <th>1199</th>\n",
       "      <th>1200</th>\n",
       "      <th>1201</th>\n",
       "      <th>1202</th>\n",
       "      <th>1203</th>\n",
       "      <th>1204</th>\n",
       "      <th>1205</th>\n",
       "      <th>1206</th>\n",
       "      <th>1207</th>\n",
       "      <th>1208</th>\n",
       "      <th>1209</th>\n",
       "      <th>1210</th>\n",
       "      <th>1211</th>\n",
       "      <th>1212</th>\n",
       "      <th>1213</th>\n",
       "      <th>1214</th>\n",
       "      <th>1215</th>\n",
       "      <th>1216</th>\n",
       "      <th>1217</th>\n",
       "      <th>1218</th>\n",
       "      <th>1219</th>\n",
       "      <th>1220</th>\n",
       "      <th>1221</th>\n",
       "      <th>1222</th>\n",
       "      <th>1223</th>\n",
       "      <th>1224</th>\n",
       "      <th>1225</th>\n",
       "      <th>1226</th>\n",
       "      <th>1227</th>\n",
       "      <th>1228</th>\n",
       "      <th>1229</th>\n",
       "      <th>1230</th>\n",
       "      <th>1231</th>\n",
       "      <th>1232</th>\n",
       "      <th>1233</th>\n",
       "      <th>1234</th>\n",
       "      <th>1235</th>\n",
       "      <th>1236</th>\n",
       "      <th>1237</th>\n",
       "      <th>1238</th>\n",
       "      <th>1239</th>\n",
       "      <th>1240</th>\n",
       "      <th>1241</th>\n",
       "      <th>1242</th>\n",
       "      <th>1243</th>\n",
       "      <th>1244</th>\n",
       "      <th>1245</th>\n",
       "      <th>1246</th>\n",
       "      <th>1247</th>\n",
       "      <th>1248</th>\n",
       "      <th>1249</th>\n",
       "      <th>1250</th>\n",
       "      <th>1251</th>\n",
       "      <th>1252</th>\n",
       "      <th>1253</th>\n",
       "      <th>1254</th>\n",
       "      <th>1255</th>\n",
       "      <th>1256</th>\n",
       "      <th>1257</th>\n",
       "      <th>1258</th>\n",
       "      <th>1259</th>\n",
       "      <th>1260</th>\n",
       "      <th>1261</th>\n",
       "      <th>1262</th>\n",
       "      <th>1263</th>\n",
       "      <th>1264</th>\n",
       "      <th>1265</th>\n",
       "      <th>1266</th>\n",
       "      <th>1267</th>\n",
       "      <th>1268</th>\n",
       "      <th>1269</th>\n",
       "      <th>1270</th>\n",
       "      <th>1271</th>\n",
       "      <th>1272</th>\n",
       "      <th>1273</th>\n",
       "      <th>1274</th>\n",
       "      <th>1275</th>\n",
       "      <th>1276</th>\n",
       "      <th>1277</th>\n",
       "      <th>1278</th>\n",
       "      <th>1279</th>\n",
       "      <th>pH2</th>\n",
       "      <th>len</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.002781</td>\n",
       "      <td>0.002993</td>\n",
       "      <td>0.000917</td>\n",
       "      <td>-0.002048</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>-0.001373</td>\n",
       "      <td>0.003532</td>\n",
       "      <td>-0.001310</td>\n",
       "      <td>0.000956</td>\n",
       "      <td>0.000494</td>\n",
       "      <td>0.001978</td>\n",
       "      <td>0.002956</td>\n",
       "      <td>-0.001324</td>\n",
       "      <td>0.000159</td>\n",
       "      <td>-0.004518</td>\n",
       "      <td>0.001749</td>\n",
       "      <td>-0.000429</td>\n",
       "      <td>0.000160</td>\n",
       "      <td>-0.002305</td>\n",
       "      <td>-0.001531</td>\n",
       "      <td>-0.003535</td>\n",
       "      <td>0.000692</td>\n",
       "      <td>0.004050</td>\n",
       "      <td>-0.001401</td>\n",
       "      <td>-0.002957</td>\n",
       "      <td>-0.001412</td>\n",
       "      <td>-0.002671</td>\n",
       "      <td>-0.005783</td>\n",
       "      <td>-0.001800</td>\n",
       "      <td>0.000789</td>\n",
       "      <td>0.000644</td>\n",
       "      <td>-0.001406</td>\n",
       "      <td>0.002964</td>\n",
       "      <td>0.002923</td>\n",
       "      <td>0.000331</td>\n",
       "      <td>-0.001763</td>\n",
       "      <td>0.002445</td>\n",
       "      <td>0.000857</td>\n",
       "      <td>0.003599</td>\n",
       "      <td>0.002084</td>\n",
       "      <td>0.000838</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.002288</td>\n",
       "      <td>-0.002258</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.003599</td>\n",
       "      <td>-0.000986</td>\n",
       "      <td>-0.000161</td>\n",
       "      <td>0.000132</td>\n",
       "      <td>0.001182</td>\n",
       "      <td>0.000753</td>\n",
       "      <td>-0.000701</td>\n",
       "      <td>-0.003558</td>\n",
       "      <td>0.001556</td>\n",
       "      <td>-0.001667</td>\n",
       "      <td>0.000404</td>\n",
       "      <td>-0.002945</td>\n",
       "      <td>-0.000815</td>\n",
       "      <td>0.000181</td>\n",
       "      <td>-0.001925</td>\n",
       "      <td>-0.000805</td>\n",
       "      <td>-0.000866</td>\n",
       "      <td>0.001052</td>\n",
       "      <td>0.002684</td>\n",
       "      <td>-0.001088</td>\n",
       "      <td>0.000095</td>\n",
       "      <td>-0.000506</td>\n",
       "      <td>-0.000254</td>\n",
       "      <td>0.002048</td>\n",
       "      <td>-0.000409</td>\n",
       "      <td>0.001096</td>\n",
       "      <td>0.002053</td>\n",
       "      <td>-0.000217</td>\n",
       "      <td>0.001507</td>\n",
       "      <td>0.001486</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>-0.004411</td>\n",
       "      <td>-0.000653</td>\n",
       "      <td>-0.004783</td>\n",
       "      <td>-0.001617</td>\n",
       "      <td>0.002622</td>\n",
       "      <td>-0.000836</td>\n",
       "      <td>0.000663</td>\n",
       "      <td>0.002321</td>\n",
       "      <td>0.000604</td>\n",
       "      <td>-0.001914</td>\n",
       "      <td>-0.001732</td>\n",
       "      <td>-0.001250</td>\n",
       "      <td>0.003528</td>\n",
       "      <td>-0.002242</td>\n",
       "      <td>-0.000436</td>\n",
       "      <td>0.003464</td>\n",
       "      <td>-0.003407</td>\n",
       "      <td>0.001447</td>\n",
       "      <td>-0.001400</td>\n",
       "      <td>-0.000898</td>\n",
       "      <td>-0.003024</td>\n",
       "      <td>0.000172</td>\n",
       "      <td>-0.001813</td>\n",
       "      <td>0.000429</td>\n",
       "      <td>0.000182</td>\n",
       "      <td>0.001863</td>\n",
       "      <td>-0.001118</td>\n",
       "      <td>-0.000239</td>\n",
       "      <td>0.000214</td>\n",
       "      <td>-0.000794</td>\n",
       "      <td>0.000371</td>\n",
       "      <td>-0.004499</td>\n",
       "      <td>-0.001445</td>\n",
       "      <td>-0.000384</td>\n",
       "      <td>0.000988</td>\n",
       "      <td>-0.003692</td>\n",
       "      <td>-0.002095</td>\n",
       "      <td>0.003049</td>\n",
       "      <td>0.000173</td>\n",
       "      <td>-0.000566</td>\n",
       "      <td>-0.003763</td>\n",
       "      <td>-0.000194</td>\n",
       "      <td>-0.001850</td>\n",
       "      <td>0.000367</td>\n",
       "      <td>0.000450</td>\n",
       "      <td>0.004017</td>\n",
       "      <td>0.001443</td>\n",
       "      <td>0.001012</td>\n",
       "      <td>-0.005538</td>\n",
       "      <td>0.000612</td>\n",
       "      <td>0.003135</td>\n",
       "      <td>-0.003770</td>\n",
       "      <td>0.002729</td>\n",
       "      <td>0.004400</td>\n",
       "      <td>-0.003667</td>\n",
       "      <td>-0.002163</td>\n",
       "      <td>-0.004647</td>\n",
       "      <td>0.002732</td>\n",
       "      <td>0.000223</td>\n",
       "      <td>-0.002755</td>\n",
       "      <td>-0.001669</td>\n",
       "      <td>-0.003186</td>\n",
       "      <td>-0.000577</td>\n",
       "      <td>-0.000050</td>\n",
       "      <td>-0.001026</td>\n",
       "      <td>0.000400</td>\n",
       "      <td>-0.002904</td>\n",
       "      <td>-0.002644</td>\n",
       "      <td>0.000031</td>\n",
       "      <td>0.000291</td>\n",
       "      <td>0.000299</td>\n",
       "      <td>-0.001210</td>\n",
       "      <td>-0.006243</td>\n",
       "      <td>-0.000687</td>\n",
       "      <td>0.000380</td>\n",
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       "      <td>-0.001479</td>\n",
       "      <td>-0.002883</td>\n",
       "      <td>0.001939</td>\n",
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       "      <td>0.005660</td>\n",
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       "      <td>0.002197</td>\n",
       "      <td>-0.004241</td>\n",
       "      <td>-0.000442</td>\n",
       "      <td>0.001944</td>\n",
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       "      <td>0.001196</td>\n",
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       "      <td>-0.000928</td>\n",
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       "      <td>-0.001801</td>\n",
       "      <td>-0.000689</td>\n",
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       "      <td>0.001668</td>\n",
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       "      <td>-0.000894</td>\n",
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       "      <td>0.001212</td>\n",
       "      <td>0.000961</td>\n",
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       "      <td>-0.002250</td>\n",
       "      <td>-0.000303</td>\n",
       "      <td>0.001081</td>\n",
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       "      <td>0.001176</td>\n",
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       "      <td>0.001025</td>\n",
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       "      <td>0.003410</td>\n",
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       "      <td>0.002494</td>\n",
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       "      <td>0.001949</td>\n",
       "      <td>-0.002215</td>\n",
       "      <td>-0.001377</td>\n",
       "      <td>-0.001671</td>\n",
       "      <td>-0.000102</td>\n",
       "      <td>-0.000053</td>\n",
       "      <td>0.001773</td>\n",
       "      <td>-0.000605</td>\n",
       "      <td>0.003062</td>\n",
       "      <td>-0.002969</td>\n",
       "      <td>0.001387</td>\n",
       "      <td>-0.002893</td>\n",
       "      <td>0.004608</td>\n",
       "      <td>-0.009759</td>\n",
       "      <td>-0.000467</td>\n",
       "      <td>-0.001026</td>\n",
       "      <td>-0.002025</td>\n",
       "      <td>0.001440</td>\n",
       "      <td>-0.002747</td>\n",
       "      <td>0.002088</td>\n",
       "      <td>-0.001724</td>\n",
       "      <td>-0.002838</td>\n",
       "      <td>-0.002127</td>\n",
       "      <td>0.003677</td>\n",
       "      <td>0.002016</td>\n",
       "      <td>0.001546</td>\n",
       "      <td>-0.001741</td>\n",
       "      <td>0.001510</td>\n",
       "      <td>-0.001113</td>\n",
       "      <td>0.001662</td>\n",
       "      <td>-0.000501</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.004534</td>\n",
       "      <td>0.000573</td>\n",
       "      <td>-0.001017</td>\n",
       "      <td>-0.002650</td>\n",
       "      <td>-0.001745</td>\n",
       "      <td>-0.005446</td>\n",
       "      <td>0.000536</td>\n",
       "      <td>0.004595</td>\n",
       "      <td>0.002023</td>\n",
       "      <td>-0.002019</td>\n",
       "      <td>0.000818</td>\n",
       "      <td>0.000109</td>\n",
       "      <td>-0.002595</td>\n",
       "      <td>-0.001626</td>\n",
       "      <td>-0.001233</td>\n",
       "      <td>-0.003847</td>\n",
       "      <td>-0.001084</td>\n",
       "      <td>-0.003103</td>\n",
       "      <td>-0.000539</td>\n",
       "      <td>-0.001490</td>\n",
       "      <td>-0.000440</td>\n",
       "      <td>-0.002124</td>\n",
       "      <td>0.003751</td>\n",
       "      <td>-0.000367</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.001289</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>-0.001323</td>\n",
       "      <td>-0.001821</td>\n",
       "      <td>0.004077</td>\n",
       "      <td>0.000467</td>\n",
       "      <td>-0.003403</td>\n",
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       "      <td>0.000083</td>\n",
       "      <td>0.000068</td>\n",
       "      <td>-0.004587</td>\n",
       "      <td>0.001150</td>\n",
       "      <td>0.000902</td>\n",
       "      <td>-0.002962</td>\n",
       "      <td>-0.000142</td>\n",
       "      <td>0.000273</td>\n",
       "      <td>-0.003524</td>\n",
       "      <td>-0.002949</td>\n",
       "      <td>0.001273</td>\n",
       "      <td>0.001474</td>\n",
       "      <td>-0.004824</td>\n",
       "      <td>0.000181</td>\n",
       "      <td>-0.000480</td>\n",
       "      <td>0.001049</td>\n",
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       "      <td>-0.000890</td>\n",
       "      <td>0.003558</td>\n",
       "      <td>0.001836</td>\n",
       "      <td>0.001477</td>\n",
       "      <td>-0.001552</td>\n",
       "      <td>-0.002074</td>\n",
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       "      <td>-0.000066</td>\n",
       "      <td>-0.001176</td>\n",
       "      <td>0.000989</td>\n",
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       "      <td>-0.001257</td>\n",
       "      <td>0.000928</td>\n",
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       "      <td>-0.000074</td>\n",
       "      <td>-0.000415</td>\n",
       "      <td>0.002280</td>\n",
       "      <td>-0.002980</td>\n",
       "      <td>0.003455</td>\n",
       "      <td>0.002121</td>\n",
       "      <td>-0.001624</td>\n",
       "      <td>-0.001211</td>\n",
       "      <td>-0.002276</td>\n",
       "      <td>0.003360</td>\n",
       "      <td>-0.001219</td>\n",
       "      <td>0.004031</td>\n",
       "      <td>-0.001006</td>\n",
       "      <td>-0.000686</td>\n",
       "      <td>-0.002878</td>\n",
       "      <td>0.003613</td>\n",
       "      <td>-0.001989</td>\n",
       "      <td>-0.003498</td>\n",
       "      <td>0.002401</td>\n",
       "      <td>0.001700</td>\n",
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       "      <td>-0.001529</td>\n",
       "      <td>-0.002194</td>\n",
       "      <td>-0.000052</td>\n",
       "      <td>0.002076</td>\n",
       "      <td>-0.000348</td>\n",
       "      <td>0.002046</td>\n",
       "      <td>-0.001021</td>\n",
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       "      <td>-0.001160</td>\n",
       "      <td>0.000913</td>\n",
       "      <td>-0.001759</td>\n",
       "      <td>-0.002985</td>\n",
       "      <td>-0.003507</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.003134</td>\n",
       "      <td>-0.000717</td>\n",
       "      <td>0.000744</td>\n",
       "      <td>-0.000367</td>\n",
       "      <td>0.004645</td>\n",
       "      <td>-0.001242</td>\n",
       "      <td>-0.001945</td>\n",
       "      <td>0.003551</td>\n",
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       "      <td>-0.001539</td>\n",
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       "      <td>-0.001460</td>\n",
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       "      <td>-0.000519</td>\n",
       "      <td>-0.001487</td>\n",
       "      <td>-0.003688</td>\n",
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       "      <td>-0.000977</td>\n",
       "      <td>-0.005536</td>\n",
       "      <td>-0.000425</td>\n",
       "      <td>0.001897</td>\n",
       "      <td>0.002086</td>\n",
       "      <td>0.002615</td>\n",
       "      <td>0.002713</td>\n",
       "      <td>0.002094</td>\n",
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       "      <td>-0.000191</td>\n",
       "      <td>0.002261</td>\n",
       "      <td>0.003197</td>\n",
       "      <td>-0.001123</td>\n",
       "      <td>0.002689</td>\n",
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       "      <td>-0.000251</td>\n",
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       "      <td>-0.001858</td>\n",
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       "      <td>-0.001152</td>\n",
       "      <td>-0.000307</td>\n",
       "      <td>0.005476</td>\n",
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       "      <td>-0.000374</td>\n",
       "      <td>-0.000440</td>\n",
       "      <td>-0.002342</td>\n",
       "      <td>0.000334</td>\n",
       "      <td>0.002125</td>\n",
       "      <td>0.005708</td>\n",
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       "      <td>-0.000775</td>\n",
       "      <td>-0.000653</td>\n",
       "      <td>-0.002999</td>\n",
       "      <td>0.004228</td>\n",
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       "      <td>-0.000660</td>\n",
       "      <td>0.005725</td>\n",
       "      <td>0.003634</td>\n",
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       "      <td>0.000908</td>\n",
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       "      <td>-0.001680</td>\n",
       "      <td>-0.000604</td>\n",
       "      <td>0.001954</td>\n",
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       "      <td>-0.001063</td>\n",
       "      <td>-0.002327</td>\n",
       "      <td>0.000408</td>\n",
       "      <td>0.003179</td>\n",
       "      <td>0.001682</td>\n",
       "      <td>-0.001548</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.000899</td>\n",
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       "      <td>-0.000725</td>\n",
       "      <td>-0.000728</td>\n",
       "      <td>-0.000882</td>\n",
       "      <td>0.002811</td>\n",
       "      <td>-0.000703</td>\n",
       "      <td>0.000945</td>\n",
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       "      <td>-0.001638</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.001676</td>\n",
       "      <td>-0.000684</td>\n",
       "      <td>-0.002657</td>\n",
       "      <td>0.000687</td>\n",
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       "      <td>-0.000906</td>\n",
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       "      <td>-0.000802</td>\n",
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       "      <td>0.001040</td>\n",
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       "      <td>0.000707</td>\n",
       "      <td>...</td>\n",
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       "      <td>-0.001086</td>\n",
       "      <td>-0.000830</td>\n",
       "      <td>-0.003101</td>\n",
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       "      <td>-0.000040</td>\n",
       "      <td>-0.001690</td>\n",
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       "      <td>-0.001787</td>\n",
       "      <td>-0.000589</td>\n",
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       "      <td>-0.000869</td>\n",
       "      <td>-0.000170</td>\n",
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       "      <td>-0.001766</td>\n",
       "      <td>-0.001744</td>\n",
       "      <td>-0.002330</td>\n",
       "      <td>0.002384</td>\n",
       "      <td>-0.000854</td>\n",
       "      <td>-0.002230</td>\n",
       "      <td>0.000648</td>\n",
       "      <td>-0.001548</td>\n",
       "      <td>0.000798</td>\n",
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       "      <td>0.001181</td>\n",
       "      <td>-0.003180</td>\n",
       "      <td>0.001081</td>\n",
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       "      <td>-0.001532</td>\n",
       "      <td>-0.003532</td>\n",
       "      <td>-0.000041</td>\n",
       "      <td>-0.001449</td>\n",
       "      <td>-0.003155</td>\n",
       "      <td>-0.000677</td>\n",
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       "      <td>0.001033</td>\n",
       "      <td>-0.001710</td>\n",
       "      <td>0.002211</td>\n",
       "      <td>0.003153</td>\n",
       "      <td>-0.003671</td>\n",
       "      <td>-0.000067</td>\n",
       "      <td>-0.001008</td>\n",
       "      <td>-0.000735</td>\n",
       "      <td>-0.000050</td>\n",
       "      <td>-0.001250</td>\n",
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       "      <td>-0.000275</td>\n",
       "      <td>0.001370</td>\n",
       "      <td>0.000130</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>0.001910</td>\n",
       "      <td>0.000543</td>\n",
       "      <td>0.014262</td>\n",
       "      <td>0.001064</td>\n",
       "      <td>-0.001312</td>\n",
       "      <td>0.000806</td>\n",
       "      <td>-0.000663</td>\n",
       "      <td>-0.001911</td>\n",
       "      <td>-0.000124</td>\n",
       "      <td>-0.002792</td>\n",
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       "      <td>-0.003076</td>\n",
       "      <td>0.002132</td>\n",
       "      <td>0.001743</td>\n",
       "      <td>-0.000668</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>0.003284</td>\n",
       "      <td>-0.001591</td>\n",
       "      <td>0.003270</td>\n",
       "      <td>-0.001599</td>\n",
       "      <td>-0.002919</td>\n",
       "      <td>0.001687</td>\n",
       "      <td>0.003127</td>\n",
       "      <td>-0.001044</td>\n",
       "      <td>0.001535</td>\n",
       "      <td>-0.001130</td>\n",
       "      <td>0.003034</td>\n",
       "      <td>-0.003500</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001365</td>\n",
       "      <td>0.001214</td>\n",
       "      <td>-0.001045</td>\n",
       "      <td>0.001286</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.000340</td>\n",
       "      <td>-0.002049</td>\n",
       "      <td>-0.002644</td>\n",
       "      <td>-0.000833</td>\n",
       "      <td>-0.002612</td>\n",
       "      <td>0.000240</td>\n",
       "      <td>0.000381</td>\n",
       "      <td>-0.000718</td>\n",
       "      <td>-0.001947</td>\n",
       "      <td>-0.001996</td>\n",
       "      <td>-0.001519</td>\n",
       "      <td>0.001351</td>\n",
       "      <td>-0.000675</td>\n",
       "      <td>-0.001213</td>\n",
       "      <td>-0.000648</td>\n",
       "      <td>-0.002192</td>\n",
       "      <td>-0.002354</td>\n",
       "      <td>0.004700</td>\n",
       "      <td>0.003405</td>\n",
       "      <td>-0.002298</td>\n",
       "      <td>0.003752</td>\n",
       "      <td>-0.001438</td>\n",
       "      <td>-0.000931</td>\n",
       "      <td>-0.001868</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.002735</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>0.003794</td>\n",
       "      <td>0.001220</td>\n",
       "      <td>-0.003992</td>\n",
       "      <td>0.002243</td>\n",
       "      <td>-0.002790</td>\n",
       "      <td>0.003242</td>\n",
       "      <td>0.000895</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>0.000613</td>\n",
       "      <td>-0.001099</td>\n",
       "      <td>-0.000938</td>\n",
       "      <td>0.000435</td>\n",
       "      <td>0.001427</td>\n",
       "      <td>-0.000020</td>\n",
       "      <td>0.003915</td>\n",
       "      <td>-0.003550</td>\n",
       "      <td>-0.002878</td>\n",
       "      <td>-0.000154</td>\n",
       "      <td>0.004259</td>\n",
       "      <td>0.002134</td>\n",
       "      <td>-0.000896</td>\n",
       "      <td>-0.000822</td>\n",
       "      <td>-0.002914</td>\n",
       "      <td>0.000752</td>\n",
       "      <td>-0.001691</td>\n",
       "      <td>-0.001337</td>\n",
       "      <td>0.001714</td>\n",
       "      <td>0.003253</td>\n",
       "      <td>0.000719</td>\n",
       "      <td>0.001495</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.002146</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>0.000229</td>\n",
       "      <td>-0.001650</td>\n",
       "      <td>-0.002190</td>\n",
       "      <td>0.002390</td>\n",
       "      <td>0.000233</td>\n",
       "      <td>-0.000022</td>\n",
       "      <td>-0.000491</td>\n",
       "      <td>0.002442</td>\n",
       "      <td>-0.000788</td>\n",
       "      <td>-0.002966</td>\n",
       "      <td>0.000764</td>\n",
       "      <td>-0.001282</td>\n",
       "      <td>0.001701</td>\n",
       "      <td>0.001378</td>\n",
       "      <td>0.001369</td>\n",
       "      <td>-0.000157</td>\n",
       "      <td>-0.001197</td>\n",
       "      <td>-0.000131</td>\n",
       "      <td>0.001362</td>\n",
       "      <td>0.001754</td>\n",
       "      <td>-0.000465</td>\n",
       "      <td>-0.002500</td>\n",
       "      <td>0.000516</td>\n",
       "      <td>0.000393</td>\n",
       "      <td>0.000094</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.002362</td>\n",
       "      <td>-0.001563</td>\n",
       "      <td>0.001944</td>\n",
       "      <td>0.003385</td>\n",
       "      <td>0.001005</td>\n",
       "      <td>-0.001009</td>\n",
       "      <td>0.001133</td>\n",
       "      <td>0.000253</td>\n",
       "      <td>0.003299</td>\n",
       "      <td>0.000984</td>\n",
       "      <td>0.002715</td>\n",
       "      <td>0.002471</td>\n",
       "      <td>-0.000905</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>-0.001033</td>\n",
       "      <td>0.001326</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>0.001737</td>\n",
       "      <td>-0.001938</td>\n",
       "      <td>0.001141</td>\n",
       "      <td>0.000449</td>\n",
       "      <td>0.000199</td>\n",
       "      <td>0.003148</td>\n",
       "      <td>0.000627</td>\n",
       "      <td>0.006180</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.003589</td>\n",
       "      <td>-0.001762</td>\n",
       "      <td>-0.000153</td>\n",
       "      <td>-0.002501</td>\n",
       "      <td>-0.000204</td>\n",
       "      <td>-0.000336</td>\n",
       "      <td>0.004184</td>\n",
       "      <td>0.001619</td>\n",
       "      <td>0.000964</td>\n",
       "      <td>0.002525</td>\n",
       "      <td>-0.000051</td>\n",
       "      <td>-0.001874</td>\n",
       "      <td>-0.002089</td>\n",
       "      <td>0.000454</td>\n",
       "      <td>0.000840</td>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.003808</td>\n",
       "      <td>0.000544</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.003832</td>\n",
       "      <td>0.000167</td>\n",
       "      <td>-0.003538</td>\n",
       "      <td>0.000675</td>\n",
       "      <td>0.000204</td>\n",
       "      <td>0.001931</td>\n",
       "      <td>0.000090</td>\n",
       "      <td>-0.001921</td>\n",
       "      <td>-0.001082</td>\n",
       "      <td>0.000738</td>\n",
       "      <td>-0.002090</td>\n",
       "      <td>-0.000141</td>\n",
       "      <td>0.004992</td>\n",
       "      <td>0.002439</td>\n",
       "      <td>-0.000099</td>\n",
       "      <td>0.001142</td>\n",
       "      <td>0.003668</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.001739</td>\n",
       "      <td>-0.000944</td>\n",
       "      <td>0.001349</td>\n",
       "      <td>-0.000763</td>\n",
       "      <td>0.000259</td>\n",
       "      <td>0.002354</td>\n",
       "      <td>0.001217</td>\n",
       "      <td>-0.004476</td>\n",
       "      <td>0.000971</td>\n",
       "      <td>0.005677</td>\n",
       "      <td>0.000478</td>\n",
       "      <td>-0.000240</td>\n",
       "      <td>0.000732</td>\n",
       "      <td>0.001317</td>\n",
       "      <td>-0.003606</td>\n",
       "      <td>-0.004056</td>\n",
       "      <td>-0.000326</td>\n",
       "      <td>0.001430</td>\n",
       "      <td>0.002503</td>\n",
       "      <td>0.000671</td>\n",
       "      <td>-0.002191</td>\n",
       "      <td>0.003219</td>\n",
       "      <td>0.003096</td>\n",
       "      <td>0.003174</td>\n",
       "      <td>-0.003121</td>\n",
       "      <td>-0.003061</td>\n",
       "      <td>-0.001855</td>\n",
       "      <td>0.003509</td>\n",
       "      <td>0.000144</td>\n",
       "      <td>0.000375</td>\n",
       "      <td>-0.001343</td>\n",
       "      <td>-0.000947</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>-0.002994</td>\n",
       "      <td>-0.002928</td>\n",
       "      <td>-0.002762</td>\n",
       "      <td>0.001194</td>\n",
       "      <td>-0.007311</td>\n",
       "      <td>-0.000554</td>\n",
       "      <td>-0.002575</td>\n",
       "      <td>0.000468</td>\n",
       "      <td>-0.001537</td>\n",
       "      <td>-0.002586</td>\n",
       "      <td>-0.001885</td>\n",
       "      <td>0.000400</td>\n",
       "      <td>-0.003383</td>\n",
       "      <td>0.000782</td>\n",
       "      <td>-0.000970</td>\n",
       "      <td>-0.001865</td>\n",
       "      <td>-0.004904</td>\n",
       "      <td>0.002138</td>\n",
       "      <td>-0.000328</td>\n",
       "      <td>-0.002694</td>\n",
       "      <td>0.000921</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>-0.004249</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.001905</td>\n",
       "      <td>-0.001651</td>\n",
       "      <td>0.001290</td>\n",
       "      <td>0.002213</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.002842</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>-0.000085</td>\n",
       "      <td>-0.000421</td>\n",
       "      <td>0.004339</td>\n",
       "      <td>0.000256</td>\n",
       "      <td>-0.001116</td>\n",
       "      <td>-0.000351</td>\n",
       "      <td>-0.001625</td>\n",
       "      <td>0.002542</td>\n",
       "      <td>-0.003126</td>\n",
       "      <td>-0.003200</td>\n",
       "      <td>-0.001840</td>\n",
       "      <td>0.002916</td>\n",
       "      <td>-0.000262</td>\n",
       "      <td>0.000590</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>-0.000722</td>\n",
       "      <td>-0.000840</td>\n",
       "      <td>0.000951</td>\n",
       "      <td>-0.002294</td>\n",
       "      <td>-0.002051</td>\n",
       "      <td>-0.000354</td>\n",
       "      <td>-0.001136</td>\n",
       "      <td>-0.004360</td>\n",
       "      <td>-0.000841</td>\n",
       "      <td>0.001889</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>0.003617</td>\n",
       "      <td>-0.004148</td>\n",
       "      <td>0.003030</td>\n",
       "      <td>-0.002511</td>\n",
       "      <td>-0.004899</td>\n",
       "      <td>-0.000284</td>\n",
       "      <td>-0.004649</td>\n",
       "      <td>0.001188</td>\n",
       "      <td>-0.003483</td>\n",
       "      <td>0.003035</td>\n",
       "      <td>0.000596</td>\n",
       "      <td>0.013246</td>\n",
       "      <td>0.003318</td>\n",
       "      <td>-0.001301</td>\n",
       "      <td>-0.001465</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>-0.004009</td>\n",
       "      <td>0.000236</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>0.000791</td>\n",
       "      <td>0.000537</td>\n",
       "      <td>0.001320</td>\n",
       "      <td>0.000450</td>\n",
       "      <td>0.001044</td>\n",
       "      <td>-0.001955</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001010</td>\n",
       "      <td>0.001541</td>\n",
       "      <td>-0.001902</td>\n",
       "      <td>0.004486</td>\n",
       "      <td>-0.002665</td>\n",
       "      <td>0.006165</td>\n",
       "      <td>-0.002304</td>\n",
       "      <td>0.000868</td>\n",
       "      <td>-0.002610</td>\n",
       "      <td>0.001956</td>\n",
       "      <td>0.001153</td>\n",
       "      <td>0.002845</td>\n",
       "      <td>-0.002574</td>\n",
       "      <td>0.001107</td>\n",
       "      <td>-0.001770</td>\n",
       "      <td>0.001352</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.003131</td>\n",
       "      <td>-0.000198</td>\n",
       "      <td>-0.002885</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>-0.002225</td>\n",
       "      <td>0.000261</td>\n",
       "      <td>0.000731</td>\n",
       "      <td>0.001686</td>\n",
       "      <td>-0.001446</td>\n",
       "      <td>0.001312</td>\n",
       "      <td>0.001972</td>\n",
       "      <td>-0.000159</td>\n",
       "      <td>0.002543</td>\n",
       "      <td>-0.000479</td>\n",
       "      <td>-0.002388</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>-0.000414</td>\n",
       "      <td>-0.001825</td>\n",
       "      <td>0.000848</td>\n",
       "      <td>-0.001172</td>\n",
       "      <td>-0.000149</td>\n",
       "      <td>-0.002991</td>\n",
       "      <td>-0.002600</td>\n",
       "      <td>0.002683</td>\n",
       "      <td>-0.000656</td>\n",
       "      <td>0.004757</td>\n",
       "      <td>0.000422</td>\n",
       "      <td>0.003060</td>\n",
       "      <td>-0.001358</td>\n",
       "      <td>-0.001585</td>\n",
       "      <td>-0.003439</td>\n",
       "      <td>0.001919</td>\n",
       "      <td>-0.001025</td>\n",
       "      <td>0.001760</td>\n",
       "      <td>0.001856</td>\n",
       "      <td>0.000632</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.002567</td>\n",
       "      <td>0.002947</td>\n",
       "      <td>0.000547</td>\n",
       "      <td>0.000015</td>\n",
       "      <td>0.001571</td>\n",
       "      <td>0.000081</td>\n",
       "      <td>-0.000732</td>\n",
       "      <td>-0.002646</td>\n",
       "      <td>-0.001011</td>\n",
       "      <td>-0.001619</td>\n",
       "      <td>-0.000548</td>\n",
       "      <td>-0.003270</td>\n",
       "      <td>0.003300</td>\n",
       "      <td>-0.001119</td>\n",
       "      <td>0.002761</td>\n",
       "      <td>-0.003128</td>\n",
       "      <td>-0.001320</td>\n",
       "      <td>-0.001653</td>\n",
       "      <td>0.001773</td>\n",
       "      <td>0.000190</td>\n",
       "      <td>-0.002786</td>\n",
       "      <td>0.000019</td>\n",
       "      <td>-0.000032</td>\n",
       "      <td>-0.000700</td>\n",
       "      <td>0.001483</td>\n",
       "      <td>-0.001075</td>\n",
       "      <td>0.000127</td>\n",
       "      <td>-0.004206</td>\n",
       "      <td>0.002983</td>\n",
       "      <td>0.002385</td>\n",
       "      <td>-0.000605</td>\n",
       "      <td>0.002120</td>\n",
       "      <td>-0.001941</td>\n",
       "      <td>-0.000780</td>\n",
       "      <td>-0.000602</td>\n",
       "      <td>-0.002009</td>\n",
       "      <td>0.001643</td>\n",
       "      <td>-0.001074</td>\n",
       "      <td>0.004264</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>-0.002020</td>\n",
       "      <td>0.001025</td>\n",
       "      <td>0.004722</td>\n",
       "      <td>-0.002568</td>\n",
       "      <td>0.002179</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>0.000469</td>\n",
       "      <td>-0.003451</td>\n",
       "      <td>-0.001417</td>\n",
       "      <td>2.0</td>\n",
       "      <td>164</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.002781</td>\n",
       "      <td>0.002993</td>\n",
       "      <td>0.000917</td>\n",
       "      <td>-0.002048</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>-0.001373</td>\n",
       "      <td>0.003532</td>\n",
       "      <td>-0.001310</td>\n",
       "      <td>0.000956</td>\n",
       "      <td>0.000494</td>\n",
       "      <td>0.001978</td>\n",
       "      <td>0.002956</td>\n",
       "      <td>-0.001324</td>\n",
       "      <td>0.000159</td>\n",
       "      <td>-0.004518</td>\n",
       "      <td>0.001749</td>\n",
       "      <td>-0.000429</td>\n",
       "      <td>0.000160</td>\n",
       "      <td>-0.002305</td>\n",
       "      <td>-0.001531</td>\n",
       "      <td>-0.003535</td>\n",
       "      <td>0.000692</td>\n",
       "      <td>0.004050</td>\n",
       "      <td>-0.001401</td>\n",
       "      <td>-0.002957</td>\n",
       "      <td>-0.001412</td>\n",
       "      <td>-0.002671</td>\n",
       "      <td>-0.005783</td>\n",
       "      <td>-0.001800</td>\n",
       "      <td>0.000789</td>\n",
       "      <td>0.000644</td>\n",
       "      <td>-0.001406</td>\n",
       "      <td>0.002964</td>\n",
       "      <td>0.002923</td>\n",
       "      <td>0.000331</td>\n",
       "      <td>-0.001763</td>\n",
       "      <td>0.002445</td>\n",
       "      <td>0.000857</td>\n",
       "      <td>0.003599</td>\n",
       "      <td>0.002084</td>\n",
       "      <td>0.000838</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.002288</td>\n",
       "      <td>-0.002258</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.003599</td>\n",
       "      <td>-0.000986</td>\n",
       "      <td>-0.000161</td>\n",
       "      <td>0.000132</td>\n",
       "      <td>0.001182</td>\n",
       "      <td>0.000753</td>\n",
       "      <td>-0.000701</td>\n",
       "      <td>-0.003558</td>\n",
       "      <td>0.001556</td>\n",
       "      <td>-0.001667</td>\n",
       "      <td>0.000404</td>\n",
       "      <td>-0.002945</td>\n",
       "      <td>-0.000815</td>\n",
       "      <td>0.000181</td>\n",
       "      <td>-0.001925</td>\n",
       "      <td>-0.000805</td>\n",
       "      <td>-0.000866</td>\n",
       "      <td>0.001052</td>\n",
       "      <td>0.002684</td>\n",
       "      <td>-0.001088</td>\n",
       "      <td>0.000095</td>\n",
       "      <td>-0.000506</td>\n",
       "      <td>-0.000254</td>\n",
       "      <td>0.002048</td>\n",
       "      <td>-0.000409</td>\n",
       "      <td>0.001096</td>\n",
       "      <td>0.002053</td>\n",
       "      <td>-0.000217</td>\n",
       "      <td>0.001507</td>\n",
       "      <td>0.001486</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>-0.004411</td>\n",
       "      <td>-0.000653</td>\n",
       "      <td>-0.004783</td>\n",
       "      <td>-0.001617</td>\n",
       "      <td>0.002622</td>\n",
       "      <td>-0.000836</td>\n",
       "      <td>0.000663</td>\n",
       "      <td>0.002321</td>\n",
       "      <td>0.000604</td>\n",
       "      <td>-0.001914</td>\n",
       "      <td>-0.001732</td>\n",
       "      <td>-0.001250</td>\n",
       "      <td>0.003528</td>\n",
       "      <td>-0.002242</td>\n",
       "      <td>-0.000436</td>\n",
       "      <td>0.003464</td>\n",
       "      <td>-0.003407</td>\n",
       "      <td>0.001447</td>\n",
       "      <td>-0.001400</td>\n",
       "      <td>-0.000898</td>\n",
       "      <td>-0.003024</td>\n",
       "      <td>0.000172</td>\n",
       "      <td>-0.001813</td>\n",
       "      <td>0.000429</td>\n",
       "      <td>0.000182</td>\n",
       "      <td>0.001863</td>\n",
       "      <td>-0.001118</td>\n",
       "      <td>-0.000239</td>\n",
       "      <td>0.000214</td>\n",
       "      <td>-0.000794</td>\n",
       "      <td>0.000371</td>\n",
       "      <td>-0.004499</td>\n",
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       "      <td>-0.000303</td>\n",
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       "      <td>0.001949</td>\n",
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       "      <td>-0.001377</td>\n",
       "      <td>-0.001671</td>\n",
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       "      <td>-0.000053</td>\n",
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       "      <td>-0.002969</td>\n",
       "      <td>0.001387</td>\n",
       "      <td>-0.002893</td>\n",
       "      <td>0.004608</td>\n",
       "      <td>-0.009759</td>\n",
       "      <td>-0.000467</td>\n",
       "      <td>-0.001026</td>\n",
       "      <td>-0.002025</td>\n",
       "      <td>0.001440</td>\n",
       "      <td>-0.002747</td>\n",
       "      <td>0.002088</td>\n",
       "      <td>-0.001724</td>\n",
       "      <td>-0.002838</td>\n",
       "      <td>-0.002127</td>\n",
       "      <td>0.003677</td>\n",
       "      <td>0.002016</td>\n",
       "      <td>0.001546</td>\n",
       "      <td>-0.001741</td>\n",
       "      <td>0.001510</td>\n",
       "      <td>-0.001113</td>\n",
       "      <td>0.001662</td>\n",
       "      <td>-0.000501</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.004534</td>\n",
       "      <td>0.000573</td>\n",
       "      <td>-0.001017</td>\n",
       "      <td>-0.002650</td>\n",
       "      <td>-0.001745</td>\n",
       "      <td>-0.005446</td>\n",
       "      <td>0.000536</td>\n",
       "      <td>0.004595</td>\n",
       "      <td>0.002023</td>\n",
       "      <td>-0.002019</td>\n",
       "      <td>0.000818</td>\n",
       "      <td>0.000109</td>\n",
       "      <td>-0.002595</td>\n",
       "      <td>-0.001626</td>\n",
       "      <td>-0.001233</td>\n",
       "      <td>-0.003847</td>\n",
       "      <td>-0.001084</td>\n",
       "      <td>-0.003103</td>\n",
       "      <td>-0.000539</td>\n",
       "      <td>-0.001490</td>\n",
       "      <td>-0.000440</td>\n",
       "      <td>-0.002124</td>\n",
       "      <td>0.003751</td>\n",
       "      <td>-0.000367</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.001289</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>-0.001323</td>\n",
       "      <td>-0.001821</td>\n",
       "      <td>0.004077</td>\n",
       "      <td>0.000467</td>\n",
       "      <td>-0.003403</td>\n",
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       "      <td>0.000083</td>\n",
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       "      <td>0.001150</td>\n",
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       "      <td>0.000273</td>\n",
       "      <td>-0.003524</td>\n",
       "      <td>-0.002949</td>\n",
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       "      <td>-0.001624</td>\n",
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       "      <td>-0.002276</td>\n",
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       "      <td>-0.001487</td>\n",
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       "      <td>-0.000977</td>\n",
       "      <td>-0.005536</td>\n",
       "      <td>-0.000425</td>\n",
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       "      <td>-0.002999</td>\n",
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       "      <td>-0.000660</td>\n",
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       "      <td>-0.000728</td>\n",
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       "      <td>-0.001676</td>\n",
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       "      <td>-0.002657</td>\n",
       "      <td>0.000687</td>\n",
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       "      <td>0.001040</td>\n",
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       "      <td>...</td>\n",
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       "      <td>-0.001086</td>\n",
       "      <td>-0.000830</td>\n",
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       "      <td>-0.000869</td>\n",
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       "      <td>-0.001529</td>\n",
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       "      <td>-0.001766</td>\n",
       "      <td>-0.001744</td>\n",
       "      <td>-0.002330</td>\n",
       "      <td>0.002384</td>\n",
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       "      <td>-0.000041</td>\n",
       "      <td>-0.001449</td>\n",
       "      <td>-0.003155</td>\n",
       "      <td>-0.000677</td>\n",
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       "      <td>0.001033</td>\n",
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       "      <td>-0.000067</td>\n",
       "      <td>-0.001008</td>\n",
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       "      <td>-0.000050</td>\n",
       "      <td>-0.001250</td>\n",
       "      <td>0.000479</td>\n",
       "      <td>0.000665</td>\n",
       "      <td>-0.000275</td>\n",
       "      <td>0.001370</td>\n",
       "      <td>0.000130</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>0.001910</td>\n",
       "      <td>0.000543</td>\n",
       "      <td>0.014262</td>\n",
       "      <td>0.001064</td>\n",
       "      <td>-0.001312</td>\n",
       "      <td>0.000806</td>\n",
       "      <td>-0.000663</td>\n",
       "      <td>-0.001911</td>\n",
       "      <td>-0.000124</td>\n",
       "      <td>-0.002792</td>\n",
       "      <td>0.004730</td>\n",
       "      <td>-0.003076</td>\n",
       "      <td>0.002132</td>\n",
       "      <td>0.001743</td>\n",
       "      <td>-0.000668</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>0.003284</td>\n",
       "      <td>-0.001591</td>\n",
       "      <td>0.003270</td>\n",
       "      <td>-0.001599</td>\n",
       "      <td>-0.002919</td>\n",
       "      <td>0.001687</td>\n",
       "      <td>0.003127</td>\n",
       "      <td>-0.001044</td>\n",
       "      <td>0.001535</td>\n",
       "      <td>-0.001130</td>\n",
       "      <td>0.003034</td>\n",
       "      <td>-0.003500</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001365</td>\n",
       "      <td>0.001214</td>\n",
       "      <td>-0.001045</td>\n",
       "      <td>0.001286</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.000340</td>\n",
       "      <td>-0.002049</td>\n",
       "      <td>-0.002644</td>\n",
       "      <td>-0.000833</td>\n",
       "      <td>-0.002612</td>\n",
       "      <td>0.000240</td>\n",
       "      <td>0.000381</td>\n",
       "      <td>-0.000718</td>\n",
       "      <td>-0.001947</td>\n",
       "      <td>-0.001996</td>\n",
       "      <td>-0.001519</td>\n",
       "      <td>0.001351</td>\n",
       "      <td>-0.000675</td>\n",
       "      <td>-0.001213</td>\n",
       "      <td>-0.000648</td>\n",
       "      <td>-0.002192</td>\n",
       "      <td>-0.002354</td>\n",
       "      <td>0.004700</td>\n",
       "      <td>0.003405</td>\n",
       "      <td>-0.002298</td>\n",
       "      <td>0.003752</td>\n",
       "      <td>-0.001438</td>\n",
       "      <td>-0.000931</td>\n",
       "      <td>-0.001868</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.002735</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>0.003794</td>\n",
       "      <td>0.001220</td>\n",
       "      <td>-0.003992</td>\n",
       "      <td>0.002243</td>\n",
       "      <td>-0.002790</td>\n",
       "      <td>0.003242</td>\n",
       "      <td>0.000895</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>0.000613</td>\n",
       "      <td>-0.001099</td>\n",
       "      <td>-0.000938</td>\n",
       "      <td>0.000435</td>\n",
       "      <td>0.001427</td>\n",
       "      <td>-0.000020</td>\n",
       "      <td>0.003915</td>\n",
       "      <td>-0.003550</td>\n",
       "      <td>-0.002878</td>\n",
       "      <td>-0.000154</td>\n",
       "      <td>0.004259</td>\n",
       "      <td>0.002134</td>\n",
       "      <td>-0.000896</td>\n",
       "      <td>-0.000822</td>\n",
       "      <td>-0.002914</td>\n",
       "      <td>0.000752</td>\n",
       "      <td>-0.001691</td>\n",
       "      <td>-0.001337</td>\n",
       "      <td>0.001714</td>\n",
       "      <td>0.003253</td>\n",
       "      <td>0.000719</td>\n",
       "      <td>0.001495</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.002146</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>0.000229</td>\n",
       "      <td>-0.001650</td>\n",
       "      <td>-0.002190</td>\n",
       "      <td>0.002390</td>\n",
       "      <td>0.000233</td>\n",
       "      <td>-0.000022</td>\n",
       "      <td>-0.000491</td>\n",
       "      <td>0.002442</td>\n",
       "      <td>-0.000788</td>\n",
       "      <td>-0.002966</td>\n",
       "      <td>0.000764</td>\n",
       "      <td>-0.001282</td>\n",
       "      <td>0.001701</td>\n",
       "      <td>0.001378</td>\n",
       "      <td>0.001369</td>\n",
       "      <td>-0.000157</td>\n",
       "      <td>-0.001197</td>\n",
       "      <td>-0.000131</td>\n",
       "      <td>0.001362</td>\n",
       "      <td>0.001754</td>\n",
       "      <td>-0.000465</td>\n",
       "      <td>-0.002500</td>\n",
       "      <td>0.000516</td>\n",
       "      <td>0.000393</td>\n",
       "      <td>0.000094</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.002362</td>\n",
       "      <td>-0.001563</td>\n",
       "      <td>0.001944</td>\n",
       "      <td>0.003385</td>\n",
       "      <td>0.001005</td>\n",
       "      <td>-0.001009</td>\n",
       "      <td>0.001133</td>\n",
       "      <td>0.000253</td>\n",
       "      <td>0.003299</td>\n",
       "      <td>0.000984</td>\n",
       "      <td>0.002715</td>\n",
       "      <td>0.002471</td>\n",
       "      <td>-0.000905</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>-0.001033</td>\n",
       "      <td>0.001326</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>0.001737</td>\n",
       "      <td>-0.001938</td>\n",
       "      <td>0.001141</td>\n",
       "      <td>0.000449</td>\n",
       "      <td>0.000199</td>\n",
       "      <td>0.003148</td>\n",
       "      <td>0.000627</td>\n",
       "      <td>0.006180</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.003589</td>\n",
       "      <td>-0.001762</td>\n",
       "      <td>-0.000153</td>\n",
       "      <td>-0.002501</td>\n",
       "      <td>-0.000204</td>\n",
       "      <td>-0.000336</td>\n",
       "      <td>0.004184</td>\n",
       "      <td>0.001619</td>\n",
       "      <td>0.000964</td>\n",
       "      <td>0.002525</td>\n",
       "      <td>-0.000051</td>\n",
       "      <td>-0.001874</td>\n",
       "      <td>-0.002089</td>\n",
       "      <td>0.000454</td>\n",
       "      <td>0.000840</td>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.003808</td>\n",
       "      <td>0.000544</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.003832</td>\n",
       "      <td>0.000167</td>\n",
       "      <td>-0.003538</td>\n",
       "      <td>0.000675</td>\n",
       "      <td>0.000204</td>\n",
       "      <td>0.001931</td>\n",
       "      <td>0.000090</td>\n",
       "      <td>-0.001921</td>\n",
       "      <td>-0.001082</td>\n",
       "      <td>0.000738</td>\n",
       "      <td>-0.002090</td>\n",
       "      <td>-0.000141</td>\n",
       "      <td>0.004992</td>\n",
       "      <td>0.002439</td>\n",
       "      <td>-0.000099</td>\n",
       "      <td>0.001142</td>\n",
       "      <td>0.003668</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.001739</td>\n",
       "      <td>-0.000944</td>\n",
       "      <td>0.001349</td>\n",
       "      <td>-0.000763</td>\n",
       "      <td>0.000259</td>\n",
       "      <td>0.002354</td>\n",
       "      <td>0.001217</td>\n",
       "      <td>-0.004476</td>\n",
       "      <td>0.000971</td>\n",
       "      <td>0.005677</td>\n",
       "      <td>0.000478</td>\n",
       "      <td>-0.000240</td>\n",
       "      <td>0.000732</td>\n",
       "      <td>0.001317</td>\n",
       "      <td>-0.003606</td>\n",
       "      <td>-0.004056</td>\n",
       "      <td>-0.000326</td>\n",
       "      <td>0.001430</td>\n",
       "      <td>0.002503</td>\n",
       "      <td>0.000671</td>\n",
       "      <td>-0.002191</td>\n",
       "      <td>0.003219</td>\n",
       "      <td>0.003096</td>\n",
       "      <td>0.003174</td>\n",
       "      <td>-0.003121</td>\n",
       "      <td>-0.003061</td>\n",
       "      <td>-0.001855</td>\n",
       "      <td>0.003509</td>\n",
       "      <td>0.000144</td>\n",
       "      <td>0.000375</td>\n",
       "      <td>-0.001343</td>\n",
       "      <td>-0.000947</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>-0.002994</td>\n",
       "      <td>-0.002928</td>\n",
       "      <td>-0.002762</td>\n",
       "      <td>0.001194</td>\n",
       "      <td>-0.007311</td>\n",
       "      <td>-0.000554</td>\n",
       "      <td>-0.002575</td>\n",
       "      <td>0.000468</td>\n",
       "      <td>-0.001537</td>\n",
       "      <td>-0.002586</td>\n",
       "      <td>-0.001885</td>\n",
       "      <td>0.000400</td>\n",
       "      <td>-0.003383</td>\n",
       "      <td>0.000782</td>\n",
       "      <td>-0.000970</td>\n",
       "      <td>-0.001865</td>\n",
       "      <td>-0.004904</td>\n",
       "      <td>0.002138</td>\n",
       "      <td>-0.000328</td>\n",
       "      <td>-0.002694</td>\n",
       "      <td>0.000921</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>-0.004249</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.001905</td>\n",
       "      <td>-0.001651</td>\n",
       "      <td>0.001290</td>\n",
       "      <td>0.002213</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.002842</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>-0.000085</td>\n",
       "      <td>-0.000421</td>\n",
       "      <td>0.004339</td>\n",
       "      <td>0.000256</td>\n",
       "      <td>-0.001116</td>\n",
       "      <td>-0.000351</td>\n",
       "      <td>-0.001625</td>\n",
       "      <td>0.002542</td>\n",
       "      <td>-0.003126</td>\n",
       "      <td>-0.003200</td>\n",
       "      <td>-0.001840</td>\n",
       "      <td>0.002916</td>\n",
       "      <td>-0.000262</td>\n",
       "      <td>0.000590</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>-0.000722</td>\n",
       "      <td>-0.000840</td>\n",
       "      <td>0.000951</td>\n",
       "      <td>-0.002294</td>\n",
       "      <td>-0.002051</td>\n",
       "      <td>-0.000354</td>\n",
       "      <td>-0.001136</td>\n",
       "      <td>-0.004360</td>\n",
       "      <td>-0.000841</td>\n",
       "      <td>0.001889</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>0.003617</td>\n",
       "      <td>-0.004148</td>\n",
       "      <td>0.003030</td>\n",
       "      <td>-0.002511</td>\n",
       "      <td>-0.004899</td>\n",
       "      <td>-0.000284</td>\n",
       "      <td>-0.004649</td>\n",
       "      <td>0.001188</td>\n",
       "      <td>-0.003483</td>\n",
       "      <td>0.003035</td>\n",
       "      <td>0.000596</td>\n",
       "      <td>0.013246</td>\n",
       "      <td>0.003318</td>\n",
       "      <td>-0.001301</td>\n",
       "      <td>-0.001465</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>-0.004009</td>\n",
       "      <td>0.000236</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>0.000791</td>\n",
       "      <td>0.000537</td>\n",
       "      <td>0.001320</td>\n",
       "      <td>0.000450</td>\n",
       "      <td>0.001044</td>\n",
       "      <td>-0.001955</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001010</td>\n",
       "      <td>0.001541</td>\n",
       "      <td>-0.001902</td>\n",
       "      <td>0.004486</td>\n",
       "      <td>-0.002665</td>\n",
       "      <td>0.006165</td>\n",
       "      <td>-0.002304</td>\n",
       "      <td>0.000868</td>\n",
       "      <td>-0.002610</td>\n",
       "      <td>0.001956</td>\n",
       "      <td>0.001153</td>\n",
       "      <td>0.002845</td>\n",
       "      <td>-0.002574</td>\n",
       "      <td>0.001107</td>\n",
       "      <td>-0.001770</td>\n",
       "      <td>0.001352</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.003131</td>\n",
       "      <td>-0.000198</td>\n",
       "      <td>-0.002885</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>-0.002225</td>\n",
       "      <td>0.000261</td>\n",
       "      <td>0.000731</td>\n",
       "      <td>0.001686</td>\n",
       "      <td>-0.001446</td>\n",
       "      <td>0.001312</td>\n",
       "      <td>0.001972</td>\n",
       "      <td>-0.000159</td>\n",
       "      <td>0.002543</td>\n",
       "      <td>-0.000479</td>\n",
       "      <td>-0.002388</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>-0.000414</td>\n",
       "      <td>-0.001825</td>\n",
       "      <td>0.000848</td>\n",
       "      <td>-0.001172</td>\n",
       "      <td>-0.000149</td>\n",
       "      <td>-0.002991</td>\n",
       "      <td>-0.002600</td>\n",
       "      <td>0.002683</td>\n",
       "      <td>-0.000656</td>\n",
       "      <td>0.004757</td>\n",
       "      <td>0.000422</td>\n",
       "      <td>0.003060</td>\n",
       "      <td>-0.001358</td>\n",
       "      <td>-0.001585</td>\n",
       "      <td>-0.003439</td>\n",
       "      <td>0.001919</td>\n",
       "      <td>-0.001025</td>\n",
       "      <td>0.001760</td>\n",
       "      <td>0.001856</td>\n",
       "      <td>0.000632</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.002567</td>\n",
       "      <td>0.002947</td>\n",
       "      <td>0.000547</td>\n",
       "      <td>0.000015</td>\n",
       "      <td>0.001571</td>\n",
       "      <td>0.000081</td>\n",
       "      <td>-0.000732</td>\n",
       "      <td>-0.002646</td>\n",
       "      <td>-0.001011</td>\n",
       "      <td>-0.001619</td>\n",
       "      <td>-0.000548</td>\n",
       "      <td>-0.003270</td>\n",
       "      <td>0.003300</td>\n",
       "      <td>-0.001119</td>\n",
       "      <td>0.002761</td>\n",
       "      <td>-0.003128</td>\n",
       "      <td>-0.001320</td>\n",
       "      <td>-0.001653</td>\n",
       "      <td>0.001773</td>\n",
       "      <td>0.000190</td>\n",
       "      <td>-0.002786</td>\n",
       "      <td>0.000019</td>\n",
       "      <td>-0.000032</td>\n",
       "      <td>-0.000700</td>\n",
       "      <td>0.001483</td>\n",
       "      <td>-0.001075</td>\n",
       "      <td>0.000127</td>\n",
       "      <td>-0.004206</td>\n",
       "      <td>0.002983</td>\n",
       "      <td>0.002385</td>\n",
       "      <td>-0.000605</td>\n",
       "      <td>0.002120</td>\n",
       "      <td>-0.001941</td>\n",
       "      <td>-0.000780</td>\n",
       "      <td>-0.000602</td>\n",
       "      <td>-0.002009</td>\n",
       "      <td>0.001643</td>\n",
       "      <td>-0.001074</td>\n",
       "      <td>0.004264</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>-0.002020</td>\n",
       "      <td>0.001025</td>\n",
       "      <td>0.004722</td>\n",
       "      <td>-0.002568</td>\n",
       "      <td>0.002179</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>0.000469</td>\n",
       "      <td>-0.003451</td>\n",
       "      <td>-0.001417</td>\n",
       "      <td>4.2</td>\n",
       "      <td>164</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.002781</td>\n",
       "      <td>0.002993</td>\n",
       "      <td>0.000917</td>\n",
       "      <td>-0.002048</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>-0.001373</td>\n",
       "      <td>0.003532</td>\n",
       "      <td>-0.001310</td>\n",
       "      <td>0.000956</td>\n",
       "      <td>0.000494</td>\n",
       "      <td>0.001978</td>\n",
       "      <td>0.002956</td>\n",
       "      <td>-0.001324</td>\n",
       "      <td>0.000159</td>\n",
       "      <td>-0.004518</td>\n",
       "      <td>0.001749</td>\n",
       "      <td>-0.000429</td>\n",
       "      <td>0.000160</td>\n",
       "      <td>-0.002305</td>\n",
       "      <td>-0.001531</td>\n",
       "      <td>-0.003535</td>\n",
       "      <td>0.000692</td>\n",
       "      <td>0.004050</td>\n",
       "      <td>-0.001401</td>\n",
       "      <td>-0.002957</td>\n",
       "      <td>-0.001412</td>\n",
       "      <td>-0.002671</td>\n",
       "      <td>-0.005783</td>\n",
       "      <td>-0.001800</td>\n",
       "      <td>0.000789</td>\n",
       "      <td>0.000644</td>\n",
       "      <td>-0.001406</td>\n",
       "      <td>0.002964</td>\n",
       "      <td>0.002923</td>\n",
       "      <td>0.000331</td>\n",
       "      <td>-0.001763</td>\n",
       "      <td>0.002445</td>\n",
       "      <td>0.000857</td>\n",
       "      <td>0.003599</td>\n",
       "      <td>0.002084</td>\n",
       "      <td>0.000838</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.002288</td>\n",
       "      <td>-0.002258</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.003599</td>\n",
       "      <td>-0.000986</td>\n",
       "      <td>-0.000161</td>\n",
       "      <td>0.000132</td>\n",
       "      <td>0.001182</td>\n",
       "      <td>0.000753</td>\n",
       "      <td>-0.000701</td>\n",
       "      <td>-0.003558</td>\n",
       "      <td>0.001556</td>\n",
       "      <td>-0.001667</td>\n",
       "      <td>0.000404</td>\n",
       "      <td>-0.002945</td>\n",
       "      <td>-0.000815</td>\n",
       "      <td>0.000181</td>\n",
       "      <td>-0.001925</td>\n",
       "      <td>-0.000805</td>\n",
       "      <td>-0.000866</td>\n",
       "      <td>0.001052</td>\n",
       "      <td>0.002684</td>\n",
       "      <td>-0.001088</td>\n",
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       "      <td>-0.001026</td>\n",
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       "      <td>-0.001745</td>\n",
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       "      <td>-0.001084</td>\n",
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       "      <td>-0.000008</td>\n",
       "      <td>-0.002139</td>\n",
       "      <td>0.000568</td>\n",
       "      <td>-0.000566</td>\n",
       "      <td>-0.000869</td>\n",
       "      <td>-0.000170</td>\n",
       "      <td>-0.001529</td>\n",
       "      <td>0.001963</td>\n",
       "      <td>-0.001766</td>\n",
       "      <td>-0.001744</td>\n",
       "      <td>-0.002330</td>\n",
       "      <td>0.002384</td>\n",
       "      <td>-0.000854</td>\n",
       "      <td>-0.002230</td>\n",
       "      <td>0.000648</td>\n",
       "      <td>-0.001548</td>\n",
       "      <td>0.000798</td>\n",
       "      <td>0.000821</td>\n",
       "      <td>-0.000661</td>\n",
       "      <td>0.001181</td>\n",
       "      <td>-0.003180</td>\n",
       "      <td>0.001081</td>\n",
       "      <td>0.000580</td>\n",
       "      <td>-0.000527</td>\n",
       "      <td>0.003656</td>\n",
       "      <td>-0.001532</td>\n",
       "      <td>-0.003532</td>\n",
       "      <td>-0.000041</td>\n",
       "      <td>-0.001449</td>\n",
       "      <td>-0.003155</td>\n",
       "      <td>-0.000677</td>\n",
       "      <td>0.003672</td>\n",
       "      <td>0.001033</td>\n",
       "      <td>-0.001710</td>\n",
       "      <td>0.002211</td>\n",
       "      <td>0.003153</td>\n",
       "      <td>-0.003671</td>\n",
       "      <td>-0.000067</td>\n",
       "      <td>-0.001008</td>\n",
       "      <td>-0.000735</td>\n",
       "      <td>-0.000050</td>\n",
       "      <td>-0.001250</td>\n",
       "      <td>0.000479</td>\n",
       "      <td>0.000665</td>\n",
       "      <td>-0.000275</td>\n",
       "      <td>0.001370</td>\n",
       "      <td>0.000130</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>0.001910</td>\n",
       "      <td>0.000543</td>\n",
       "      <td>0.014262</td>\n",
       "      <td>0.001064</td>\n",
       "      <td>-0.001312</td>\n",
       "      <td>0.000806</td>\n",
       "      <td>-0.000663</td>\n",
       "      <td>-0.001911</td>\n",
       "      <td>-0.000124</td>\n",
       "      <td>-0.002792</td>\n",
       "      <td>0.004730</td>\n",
       "      <td>-0.003076</td>\n",
       "      <td>0.002132</td>\n",
       "      <td>0.001743</td>\n",
       "      <td>-0.000668</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>0.003284</td>\n",
       "      <td>-0.001591</td>\n",
       "      <td>0.003270</td>\n",
       "      <td>-0.001599</td>\n",
       "      <td>-0.002919</td>\n",
       "      <td>0.001687</td>\n",
       "      <td>0.003127</td>\n",
       "      <td>-0.001044</td>\n",
       "      <td>0.001535</td>\n",
       "      <td>-0.001130</td>\n",
       "      <td>0.003034</td>\n",
       "      <td>-0.003500</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001365</td>\n",
       "      <td>0.001214</td>\n",
       "      <td>-0.001045</td>\n",
       "      <td>0.001286</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.000340</td>\n",
       "      <td>-0.002049</td>\n",
       "      <td>-0.002644</td>\n",
       "      <td>-0.000833</td>\n",
       "      <td>-0.002612</td>\n",
       "      <td>0.000240</td>\n",
       "      <td>0.000381</td>\n",
       "      <td>-0.000718</td>\n",
       "      <td>-0.001947</td>\n",
       "      <td>-0.001996</td>\n",
       "      <td>-0.001519</td>\n",
       "      <td>0.001351</td>\n",
       "      <td>-0.000675</td>\n",
       "      <td>-0.001213</td>\n",
       "      <td>-0.000648</td>\n",
       "      <td>-0.002192</td>\n",
       "      <td>-0.002354</td>\n",
       "      <td>0.004700</td>\n",
       "      <td>0.003405</td>\n",
       "      <td>-0.002298</td>\n",
       "      <td>0.003752</td>\n",
       "      <td>-0.001438</td>\n",
       "      <td>-0.000931</td>\n",
       "      <td>-0.001868</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.002735</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>0.003794</td>\n",
       "      <td>0.001220</td>\n",
       "      <td>-0.003992</td>\n",
       "      <td>0.002243</td>\n",
       "      <td>-0.002790</td>\n",
       "      <td>0.003242</td>\n",
       "      <td>0.000895</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>0.000613</td>\n",
       "      <td>-0.001099</td>\n",
       "      <td>-0.000938</td>\n",
       "      <td>0.000435</td>\n",
       "      <td>0.001427</td>\n",
       "      <td>-0.000020</td>\n",
       "      <td>0.003915</td>\n",
       "      <td>-0.003550</td>\n",
       "      <td>-0.002878</td>\n",
       "      <td>-0.000154</td>\n",
       "      <td>0.004259</td>\n",
       "      <td>0.002134</td>\n",
       "      <td>-0.000896</td>\n",
       "      <td>-0.000822</td>\n",
       "      <td>-0.002914</td>\n",
       "      <td>0.000752</td>\n",
       "      <td>-0.001691</td>\n",
       "      <td>-0.001337</td>\n",
       "      <td>0.001714</td>\n",
       "      <td>0.003253</td>\n",
       "      <td>0.000719</td>\n",
       "      <td>0.001495</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.002146</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>0.000229</td>\n",
       "      <td>-0.001650</td>\n",
       "      <td>-0.002190</td>\n",
       "      <td>0.002390</td>\n",
       "      <td>0.000233</td>\n",
       "      <td>-0.000022</td>\n",
       "      <td>-0.000491</td>\n",
       "      <td>0.002442</td>\n",
       "      <td>-0.000788</td>\n",
       "      <td>-0.002966</td>\n",
       "      <td>0.000764</td>\n",
       "      <td>-0.001282</td>\n",
       "      <td>0.001701</td>\n",
       "      <td>0.001378</td>\n",
       "      <td>0.001369</td>\n",
       "      <td>-0.000157</td>\n",
       "      <td>-0.001197</td>\n",
       "      <td>-0.000131</td>\n",
       "      <td>0.001362</td>\n",
       "      <td>0.001754</td>\n",
       "      <td>-0.000465</td>\n",
       "      <td>-0.002500</td>\n",
       "      <td>0.000516</td>\n",
       "      <td>0.000393</td>\n",
       "      <td>0.000094</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.002362</td>\n",
       "      <td>-0.001563</td>\n",
       "      <td>0.001944</td>\n",
       "      <td>0.003385</td>\n",
       "      <td>0.001005</td>\n",
       "      <td>-0.001009</td>\n",
       "      <td>0.001133</td>\n",
       "      <td>0.000253</td>\n",
       "      <td>0.003299</td>\n",
       "      <td>0.000984</td>\n",
       "      <td>0.002715</td>\n",
       "      <td>0.002471</td>\n",
       "      <td>-0.000905</td>\n",
       "      <td>0.002816</td>\n",
       "      <td>-0.001033</td>\n",
       "      <td>0.001326</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>0.001737</td>\n",
       "      <td>-0.001938</td>\n",
       "      <td>0.001141</td>\n",
       "      <td>0.000449</td>\n",
       "      <td>0.000199</td>\n",
       "      <td>0.003148</td>\n",
       "      <td>0.000627</td>\n",
       "      <td>0.006180</td>\n",
       "      <td>-0.000715</td>\n",
       "      <td>-0.003589</td>\n",
       "      <td>-0.001762</td>\n",
       "      <td>-0.000153</td>\n",
       "      <td>-0.002501</td>\n",
       "      <td>-0.000204</td>\n",
       "      <td>-0.000336</td>\n",
       "      <td>0.004184</td>\n",
       "      <td>0.001619</td>\n",
       "      <td>0.000964</td>\n",
       "      <td>0.002525</td>\n",
       "      <td>-0.000051</td>\n",
       "      <td>-0.001874</td>\n",
       "      <td>-0.002089</td>\n",
       "      <td>0.000454</td>\n",
       "      <td>0.000840</td>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.003808</td>\n",
       "      <td>0.000544</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.003832</td>\n",
       "      <td>0.000167</td>\n",
       "      <td>-0.003538</td>\n",
       "      <td>0.000675</td>\n",
       "      <td>0.000204</td>\n",
       "      <td>0.001931</td>\n",
       "      <td>0.000090</td>\n",
       "      <td>-0.001921</td>\n",
       "      <td>-0.001082</td>\n",
       "      <td>0.000738</td>\n",
       "      <td>-0.002090</td>\n",
       "      <td>-0.000141</td>\n",
       "      <td>0.004992</td>\n",
       "      <td>0.002439</td>\n",
       "      <td>-0.000099</td>\n",
       "      <td>0.001142</td>\n",
       "      <td>0.003668</td>\n",
       "      <td>0.001605</td>\n",
       "      <td>0.001739</td>\n",
       "      <td>-0.000944</td>\n",
       "      <td>0.001349</td>\n",
       "      <td>-0.000763</td>\n",
       "      <td>0.000259</td>\n",
       "      <td>0.002354</td>\n",
       "      <td>0.001217</td>\n",
       "      <td>-0.004476</td>\n",
       "      <td>0.000971</td>\n",
       "      <td>0.005677</td>\n",
       "      <td>0.000478</td>\n",
       "      <td>-0.000240</td>\n",
       "      <td>0.000732</td>\n",
       "      <td>0.001317</td>\n",
       "      <td>-0.003606</td>\n",
       "      <td>-0.004056</td>\n",
       "      <td>-0.000326</td>\n",
       "      <td>0.001430</td>\n",
       "      <td>0.002503</td>\n",
       "      <td>0.000671</td>\n",
       "      <td>-0.002191</td>\n",
       "      <td>0.003219</td>\n",
       "      <td>0.003096</td>\n",
       "      <td>0.003174</td>\n",
       "      <td>-0.003121</td>\n",
       "      <td>-0.003061</td>\n",
       "      <td>-0.001855</td>\n",
       "      <td>0.003509</td>\n",
       "      <td>0.000144</td>\n",
       "      <td>0.000375</td>\n",
       "      <td>-0.001343</td>\n",
       "      <td>-0.000947</td>\n",
       "      <td>0.000456</td>\n",
       "      <td>-0.002994</td>\n",
       "      <td>-0.002928</td>\n",
       "      <td>-0.002762</td>\n",
       "      <td>0.001194</td>\n",
       "      <td>-0.007311</td>\n",
       "      <td>-0.000554</td>\n",
       "      <td>-0.002575</td>\n",
       "      <td>0.000468</td>\n",
       "      <td>-0.001537</td>\n",
       "      <td>-0.002586</td>\n",
       "      <td>-0.001885</td>\n",
       "      <td>0.000400</td>\n",
       "      <td>-0.003383</td>\n",
       "      <td>0.000782</td>\n",
       "      <td>-0.000970</td>\n",
       "      <td>-0.001865</td>\n",
       "      <td>-0.004904</td>\n",
       "      <td>0.002138</td>\n",
       "      <td>-0.000328</td>\n",
       "      <td>-0.002694</td>\n",
       "      <td>0.000921</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>-0.004249</td>\n",
       "      <td>-0.000482</td>\n",
       "      <td>0.001905</td>\n",
       "      <td>-0.001651</td>\n",
       "      <td>0.001290</td>\n",
       "      <td>0.002213</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.002842</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>-0.000085</td>\n",
       "      <td>-0.000421</td>\n",
       "      <td>0.004339</td>\n",
       "      <td>0.000256</td>\n",
       "      <td>-0.001116</td>\n",
       "      <td>-0.000351</td>\n",
       "      <td>-0.001625</td>\n",
       "      <td>0.002542</td>\n",
       "      <td>-0.003126</td>\n",
       "      <td>-0.003200</td>\n",
       "      <td>-0.001840</td>\n",
       "      <td>0.002916</td>\n",
       "      <td>-0.000262</td>\n",
       "      <td>0.000590</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>-0.000722</td>\n",
       "      <td>-0.000840</td>\n",
       "      <td>0.000951</td>\n",
       "      <td>-0.002294</td>\n",
       "      <td>-0.002051</td>\n",
       "      <td>-0.000354</td>\n",
       "      <td>-0.001136</td>\n",
       "      <td>-0.004360</td>\n",
       "      <td>-0.000841</td>\n",
       "      <td>0.001889</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>0.003617</td>\n",
       "      <td>-0.004148</td>\n",
       "      <td>0.003030</td>\n",
       "      <td>-0.002511</td>\n",
       "      <td>-0.004899</td>\n",
       "      <td>-0.000284</td>\n",
       "      <td>-0.004649</td>\n",
       "      <td>0.001188</td>\n",
       "      <td>-0.003483</td>\n",
       "      <td>0.003035</td>\n",
       "      <td>0.000596</td>\n",
       "      <td>0.013246</td>\n",
       "      <td>0.003318</td>\n",
       "      <td>-0.001301</td>\n",
       "      <td>-0.001465</td>\n",
       "      <td>-0.000627</td>\n",
       "      <td>-0.004009</td>\n",
       "      <td>0.000236</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>0.000791</td>\n",
       "      <td>0.000537</td>\n",
       "      <td>0.001320</td>\n",
       "      <td>0.000450</td>\n",
       "      <td>0.001044</td>\n",
       "      <td>-0.001955</td>\n",
       "      <td>0.002220</td>\n",
       "      <td>-0.001010</td>\n",
       "      <td>0.001541</td>\n",
       "      <td>-0.001902</td>\n",
       "      <td>0.004486</td>\n",
       "      <td>-0.002665</td>\n",
       "      <td>0.006165</td>\n",
       "      <td>-0.002304</td>\n",
       "      <td>0.000868</td>\n",
       "      <td>-0.002610</td>\n",
       "      <td>0.001956</td>\n",
       "      <td>0.001153</td>\n",
       "      <td>0.002845</td>\n",
       "      <td>-0.002574</td>\n",
       "      <td>0.001107</td>\n",
       "      <td>-0.001770</td>\n",
       "      <td>0.001352</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.003131</td>\n",
       "      <td>-0.000198</td>\n",
       "      <td>-0.002885</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>-0.002225</td>\n",
       "      <td>0.000261</td>\n",
       "      <td>0.000731</td>\n",
       "      <td>0.001686</td>\n",
       "      <td>-0.001446</td>\n",
       "      <td>0.001312</td>\n",
       "      <td>0.001972</td>\n",
       "      <td>-0.000159</td>\n",
       "      <td>0.002543</td>\n",
       "      <td>-0.000479</td>\n",
       "      <td>-0.002388</td>\n",
       "      <td>0.000377</td>\n",
       "      <td>-0.000414</td>\n",
       "      <td>-0.001825</td>\n",
       "      <td>0.000848</td>\n",
       "      <td>-0.001172</td>\n",
       "      <td>-0.000149</td>\n",
       "      <td>-0.002991</td>\n",
       "      <td>-0.002600</td>\n",
       "      <td>0.002683</td>\n",
       "      <td>-0.000656</td>\n",
       "      <td>0.004757</td>\n",
       "      <td>0.000422</td>\n",
       "      <td>0.003060</td>\n",
       "      <td>-0.001358</td>\n",
       "      <td>-0.001585</td>\n",
       "      <td>-0.003439</td>\n",
       "      <td>0.001919</td>\n",
       "      <td>-0.001025</td>\n",
       "      <td>0.001760</td>\n",
       "      <td>0.001856</td>\n",
       "      <td>0.000632</td>\n",
       "      <td>-0.002373</td>\n",
       "      <td>-0.002567</td>\n",
       "      <td>0.002947</td>\n",
       "      <td>0.000547</td>\n",
       "      <td>0.000015</td>\n",
       "      <td>0.001571</td>\n",
       "      <td>0.000081</td>\n",
       "      <td>-0.000732</td>\n",
       "      <td>-0.002646</td>\n",
       "      <td>-0.001011</td>\n",
       "      <td>-0.001619</td>\n",
       "      <td>-0.000548</td>\n",
       "      <td>-0.003270</td>\n",
       "      <td>0.003300</td>\n",
       "      <td>-0.001119</td>\n",
       "      <td>0.002761</td>\n",
       "      <td>-0.003128</td>\n",
       "      <td>-0.001320</td>\n",
       "      <td>-0.001653</td>\n",
       "      <td>0.001773</td>\n",
       "      <td>0.000190</td>\n",
       "      <td>-0.002786</td>\n",
       "      <td>0.000019</td>\n",
       "      <td>-0.000032</td>\n",
       "      <td>-0.000700</td>\n",
       "      <td>0.001483</td>\n",
       "      <td>-0.001075</td>\n",
       "      <td>0.000127</td>\n",
       "      <td>-0.004206</td>\n",
       "      <td>0.002983</td>\n",
       "      <td>0.002385</td>\n",
       "      <td>-0.000605</td>\n",
       "      <td>0.002120</td>\n",
       "      <td>-0.001941</td>\n",
       "      <td>-0.000780</td>\n",
       "      <td>-0.000602</td>\n",
       "      <td>-0.002009</td>\n",
       "      <td>0.001643</td>\n",
       "      <td>-0.001074</td>\n",
       "      <td>0.004264</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>-0.002020</td>\n",
       "      <td>0.001025</td>\n",
       "      <td>0.004722</td>\n",
       "      <td>-0.002568</td>\n",
       "      <td>0.002179</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>0.000469</td>\n",
       "      <td>-0.003451</td>\n",
       "      <td>-0.001417</td>\n",
       "      <td>2.0</td>\n",
       "      <td>164</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0.002264</td>\n",
       "      <td>-0.002781</td>\n",
       "      <td>0.002993</td>\n",
       "      <td>0.000917</td>\n",
       "      <td>-0.002048</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>-0.001373</td>\n",
       "      <td>0.003532</td>\n",
       "      <td>-0.001310</td>\n",
       "      <td>0.000956</td>\n",
       "      <td>0.000494</td>\n",
       "      <td>0.001978</td>\n",
       "      <td>0.002956</td>\n",
       "      <td>-0.001324</td>\n",
       "      <td>0.000159</td>\n",
       "      <td>-0.004518</td>\n",
       "      <td>0.001749</td>\n",
       "      <td>-0.000429</td>\n",
       "      <td>0.000160</td>\n",
       "      <td>-0.002305</td>\n",
       "      <td>-0.001531</td>\n",
       "      <td>-0.003535</td>\n",
       "      <td>0.000692</td>\n",
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       "      <td>-0.000687</td>\n",
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       "      <td>-0.002542</td>\n",
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       "      <td>-0.002932</td>\n",
       "      <td>-0.001902</td>\n",
       "      <td>-0.001479</td>\n",
       "      <td>-0.002883</td>\n",
       "      <td>0.001939</td>\n",
       "      <td>-0.000959</td>\n",
       "      <td>0.005660</td>\n",
       "      <td>0.003752</td>\n",
       "      <td>0.002197</td>\n",
       "      <td>-0.004241</td>\n",
       "      <td>-0.000442</td>\n",
       "      <td>0.001944</td>\n",
       "      <td>-0.001895</td>\n",
       "      <td>0.001196</td>\n",
       "      <td>0.001153</td>\n",
       "      <td>-0.001157</td>\n",
       "      <td>-0.000928</td>\n",
       "      <td>-0.000634</td>\n",
       "      <td>-0.001801</td>\n",
       "      <td>-0.000689</td>\n",
       "      <td>-0.000311</td>\n",
       "      <td>0.001668</td>\n",
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       "      <td>-0.003066</td>\n",
       "      <td>-0.001738</td>\n",
       "      <td>-0.000894</td>\n",
       "      <td>0.001454</td>\n",
       "      <td>0.000284</td>\n",
       "      <td>0.001212</td>\n",
       "      <td>0.000961</td>\n",
       "      <td>0.003414</td>\n",
       "      <td>0.001085</td>\n",
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       "      <td>-0.002250</td>\n",
       "      <td>-0.000303</td>\n",
       "      <td>0.001081</td>\n",
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       "      <td>-0.000669</td>\n",
       "      <td>0.001176</td>\n",
       "      <td>0.000803</td>\n",
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       "      <td>0.001025</td>\n",
       "      <td>-0.001513</td>\n",
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       "      <td>0.003410</td>\n",
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       "      <td>0.004680</td>\n",
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       "      <td>0.002494</td>\n",
       "      <td>-0.002360</td>\n",
       "      <td>0.001776</td>\n",
       "      <td>0.001366</td>\n",
       "      <td>-0.001027</td>\n",
       "      <td>0.001949</td>\n",
       "      <td>-0.002215</td>\n",
       "      <td>-0.001377</td>\n",
       "      <td>-0.001671</td>\n",
       "      <td>-0.000102</td>\n",
       "      <td>-0.000053</td>\n",
       "      <td>0.001773</td>\n",
       "      <td>-0.000605</td>\n",
       "      <td>0.003062</td>\n",
       "      <td>-0.002969</td>\n",
       "      <td>0.001387</td>\n",
       "      <td>-0.002893</td>\n",
       "      <td>0.004608</td>\n",
       "      <td>-0.009759</td>\n",
       "      <td>-0.000467</td>\n",
       "      <td>-0.001026</td>\n",
       "      <td>-0.002025</td>\n",
       "      <td>0.001440</td>\n",
       "      <td>-0.002747</td>\n",
       "      <td>0.002088</td>\n",
       "      <td>-0.001724</td>\n",
       "      <td>-0.002838</td>\n",
       "      <td>-0.002127</td>\n",
       "      <td>0.003677</td>\n",
       "      <td>0.002016</td>\n",
       "      <td>0.001546</td>\n",
       "      <td>-0.001741</td>\n",
       "      <td>0.001510</td>\n",
       "      <td>-0.001113</td>\n",
       "      <td>0.001662</td>\n",
       "      <td>-0.000501</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.004534</td>\n",
       "      <td>0.000573</td>\n",
       "      <td>-0.001017</td>\n",
       "      <td>-0.002650</td>\n",
       "      <td>-0.001745</td>\n",
       "      <td>-0.005446</td>\n",
       "      <td>0.000536</td>\n",
       "      <td>0.004595</td>\n",
       "      <td>0.002023</td>\n",
       "      <td>-0.002019</td>\n",
       "      <td>0.000818</td>\n",
       "      <td>0.000109</td>\n",
       "      <td>-0.002595</td>\n",
       "      <td>-0.001626</td>\n",
       "      <td>-0.001233</td>\n",
       "      <td>-0.003847</td>\n",
       "      <td>-0.001084</td>\n",
       "      <td>-0.003103</td>\n",
       "      <td>-0.000539</td>\n",
       "      <td>-0.001490</td>\n",
       "      <td>-0.000440</td>\n",
       "      <td>-0.002124</td>\n",
       "      <td>0.003751</td>\n",
       "      <td>-0.000367</td>\n",
       "      <td>-0.000004</td>\n",
       "      <td>0.001289</td>\n",
       "      <td>0.000944</td>\n",
       "      <td>-0.001323</td>\n",
       "      <td>-0.001821</td>\n",
       "      <td>0.004077</td>\n",
       "      <td>0.000467</td>\n",
       "      <td>-0.003403</td>\n",
       "      <td>0.000390</td>\n",
       "      <td>0.000083</td>\n",
       "      <td>0.000068</td>\n",
       "      <td>-0.004587</td>\n",
       "      <td>0.001150</td>\n",
       "      <td>0.000902</td>\n",
       "      <td>-0.002962</td>\n",
       "      <td>-0.000142</td>\n",
       "      <td>0.000273</td>\n",
       "      <td>-0.003524</td>\n",
       "      <td>-0.002949</td>\n",
       "      <td>0.001273</td>\n",
       "      <td>0.001474</td>\n",
       "      <td>-0.004824</td>\n",
       "      <td>0.000181</td>\n",
       "      <td>-0.000480</td>\n",
       "      <td>0.001049</td>\n",
       "      <td>0.000807</td>\n",
       "      <td>0.001808</td>\n",
       "      <td>0.005382</td>\n",
       "      <td>-0.000475</td>\n",
       "      <td>-0.000890</td>\n",
       "      <td>0.003558</td>\n",
       "      <td>0.001836</td>\n",
       "      <td>0.001477</td>\n",
       "      <td>-0.001552</td>\n",
       "      <td>-0.002074</td>\n",
       "      <td>0.004700</td>\n",
       "      <td>-0.000066</td>\n",
       "      <td>-0.001176</td>\n",
       "      <td>0.000989</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>-0.001257</td>\n",
       "      <td>0.000928</td>\n",
       "      <td>0.001791</td>\n",
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       "      <td>-0.000074</td>\n",
       "      <td>-0.000415</td>\n",
       "      <td>0.002280</td>\n",
       "      <td>-0.002980</td>\n",
       "      <td>0.003455</td>\n",
       "      <td>0.002121</td>\n",
       "      <td>-0.001624</td>\n",
       "      <td>-0.001211</td>\n",
       "      <td>-0.002276</td>\n",
       "      <td>0.003360</td>\n",
       "      <td>-0.001219</td>\n",
       "      <td>0.004031</td>\n",
       "      <td>-0.001006</td>\n",
       "      <td>-0.000686</td>\n",
       "      <td>-0.002878</td>\n",
       "      <td>0.003613</td>\n",
       "      <td>-0.001989</td>\n",
       "      <td>-0.003498</td>\n",
       "      <td>0.002401</td>\n",
       "      <td>0.001700</td>\n",
       "      <td>0.001992</td>\n",
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       "      <td>-0.001529</td>\n",
       "      <td>-0.002194</td>\n",
       "      <td>-0.000052</td>\n",
       "      <td>0.002076</td>\n",
       "      <td>-0.000348</td>\n",
       "      <td>0.002046</td>\n",
       "      <td>-0.001021</td>\n",
       "      <td>0.002713</td>\n",
       "      <td>-0.001160</td>\n",
       "      <td>0.000913</td>\n",
       "      <td>-0.001759</td>\n",
       "      <td>-0.002985</td>\n",
       "      <td>-0.003507</td>\n",
       "      <td>0.000362</td>\n",
       "      <td>-0.003134</td>\n",
       "      <td>-0.000717</td>\n",
       "      <td>0.000744</td>\n",
       "      <td>-0.000367</td>\n",
       "      <td>0.004645</td>\n",
       "      <td>-0.001242</td>\n",
       "      <td>-0.001945</td>\n",
       "      <td>0.003551</td>\n",
       "      <td>0.001235</td>\n",
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       "      <td>0.002047</td>\n",
       "      <td>-0.000639</td>\n",
       "      <td>0.001136</td>\n",
       "      <td>-0.001539</td>\n",
       "      <td>0.000078</td>\n",
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       "      <td>-0.002423</td>\n",
       "      <td>-0.001460</td>\n",
       "      <td>0.001917</td>\n",
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       "      <td>0.005322</td>\n",
       "      <td>-0.000519</td>\n",
       "      <td>-0.001487</td>\n",
       "      <td>-0.003688</td>\n",
       "      <td>0.002700</td>\n",
       "      <td>-0.000977</td>\n",
       "      <td>-0.005536</td>\n",
       "      <td>-0.000425</td>\n",
       "      <td>0.001897</td>\n",
       "      <td>0.002086</td>\n",
       "      <td>0.002615</td>\n",
       "      <td>0.002713</td>\n",
       "      <td>0.002094</td>\n",
       "      <td>0.001805</td>\n",
       "      <td>-0.000191</td>\n",
       "      <td>0.002261</td>\n",
       "      <td>0.003197</td>\n",
       "      <td>-0.001123</td>\n",
       "      <td>0.002689</td>\n",
       "      <td>0.000792</td>\n",
       "      <td>-0.000754</td>\n",
       "      <td>0.002205</td>\n",
       "      <td>0.003709</td>\n",
       "      <td>0.000078</td>\n",
       "      <td>-0.003511</td>\n",
       "      <td>0.001373</td>\n",
       "      <td>-0.000251</td>\n",
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       "      <td>-0.002099</td>\n",
       "      <td>-0.001858</td>\n",
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       "      <td>-0.001152</td>\n",
       "      <td>-0.000307</td>\n",
       "      <td>0.005476</td>\n",
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       "      <td>-0.000440</td>\n",
       "      <td>-0.002342</td>\n",
       "      <td>0.000334</td>\n",
       "      <td>0.002125</td>\n",
       "      <td>0.005708</td>\n",
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       "      <td>-0.000570</td>\n",
       "      <td>0.003404</td>\n",
       "      <td>-0.000775</td>\n",
       "      <td>-0.000653</td>\n",
       "      <td>-0.002999</td>\n",
       "      <td>0.004228</td>\n",
       "      <td>-0.000514</td>\n",
       "      <td>-0.000660</td>\n",
       "      <td>0.005725</td>\n",
       "      <td>0.003634</td>\n",
       "      <td>0.003098</td>\n",
       "      <td>0.000578</td>\n",
       "      <td>0.001723</td>\n",
       "      <td>-0.001510</td>\n",
       "      <td>-0.003241</td>\n",
       "      <td>0.000908</td>\n",
       "      <td>-0.000982</td>\n",
       "      <td>-0.001680</td>\n",
       "      <td>-0.000604</td>\n",
       "      <td>0.001954</td>\n",
       "      <td>0.000015</td>\n",
       "      <td>-0.001063</td>\n",
       "      <td>-0.002327</td>\n",
       "      <td>0.000408</td>\n",
       "      <td>0.003179</td>\n",
       "      <td>0.001682</td>\n",
       "      <td>-0.001548</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.000899</td>\n",
       "      <td>0.000880</td>\n",
       "      <td>-0.002557</td>\n",
       "      <td>0.000445</td>\n",
       "      <td>0.002472</td>\n",
       "      <td>0.002234</td>\n",
       "      <td>0.001928</td>\n",
       "      <td>-0.000725</td>\n",
       "      <td>-0.000728</td>\n",
       "      <td>-0.000882</td>\n",
       "      <td>0.002811</td>\n",
       "      <td>-0.000703</td>\n",
       "      <td>0.000945</td>\n",
       "      <td>0.002185</td>\n",
       "      <td>0.001727</td>\n",
       "      <td>-0.001638</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.001676</td>\n",
       "      <td>-0.000684</td>\n",
       "      <td>-0.002657</td>\n",
       "      <td>0.000687</td>\n",
       "      <td>0.003456</td>\n",
       "      <td>0.001075</td>\n",
       "      <td>0.004571</td>\n",
       "      <td>-0.000448</td>\n",
       "      <td>0.003708</td>\n",
       "      <td>0.002320</td>\n",
       "      <td>-0.002248</td>\n",
       "      <td>0.002350</td>\n",
       "      <td>-0.001119</td>\n",
       "      <td>0.001038</td>\n",
       "      <td>-0.001551</td>\n",
       "      <td>0.002100</td>\n",
       "      <td>-0.000906</td>\n",
       "      <td>0.004947</td>\n",
       "      <td>-0.000802</td>\n",
       "      <td>0.001689</td>\n",
       "      <td>-0.004100</td>\n",
       "      <td>0.000364</td>\n",
       "      <td>0.000830</td>\n",
       "      <td>0.000120</td>\n",
       "      <td>-0.000223</td>\n",
       "      <td>0.001040</td>\n",
       "      <td>0.000934</td>\n",
       "      <td>0.000707</td>\n",
       "      <td>...</td>\n",
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       "      <td>-0.001086</td>\n",
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       "      <td>-0.000780</td>\n",
       "      <td>-0.000602</td>\n",
       "      <td>-0.002009</td>\n",
       "      <td>0.001643</td>\n",
       "      <td>-0.001074</td>\n",
       "      <td>0.004264</td>\n",
       "      <td>-0.000694</td>\n",
       "      <td>0.002568</td>\n",
       "      <td>0.003308</td>\n",
       "      <td>-0.002020</td>\n",
       "      <td>0.001025</td>\n",
       "      <td>0.004722</td>\n",
       "      <td>-0.002568</td>\n",
       "      <td>0.002179</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>0.000469</td>\n",
       "      <td>-0.003451</td>\n",
       "      <td>-0.001417</td>\n",
       "      <td>6.5</td>\n",
       "      <td>164</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0.003853</td>\n",
       "      <td>-0.001638</td>\n",
       "      <td>0.002186</td>\n",
       "      <td>0.000431</td>\n",
       "      <td>-0.000128</td>\n",
       "      <td>-0.004285</td>\n",
       "      <td>0.000982</td>\n",
       "      <td>0.001414</td>\n",
       "      <td>-0.002309</td>\n",
       "      <td>-0.001756</td>\n",
       "      <td>-0.000616</td>\n",
       "      <td>-0.001022</td>\n",
       "      <td>0.004372</td>\n",
       "      <td>0.002630</td>\n",
       "      <td>0.001775</td>\n",
       "      <td>-0.004346</td>\n",
       "      <td>0.004295</td>\n",
       "      <td>0.001574</td>\n",
       "      <td>0.001650</td>\n",
       "      <td>-0.000780</td>\n",
       "      <td>0.004574</td>\n",
       "      <td>0.000564</td>\n",
       "      <td>-0.000518</td>\n",
       "      <td>-0.000238</td>\n",
       "      <td>-0.004106</td>\n",
       "      <td>-0.001015</td>\n",
       "      <td>-0.002564</td>\n",
       "      <td>-0.000180</td>\n",
       "      <td>-0.003691</td>\n",
       "      <td>-0.003195</td>\n",
       "      <td>0.003009</td>\n",
       "      <td>-0.002052</td>\n",
       "      <td>0.000583</td>\n",
       "      <td>0.002756</td>\n",
       "      <td>0.002906</td>\n",
       "      <td>-0.001518</td>\n",
       "      <td>-0.002610</td>\n",
       "      <td>-0.000182</td>\n",
       "      <td>-0.002618</td>\n",
       "      <td>0.005253</td>\n",
       "      <td>0.001746</td>\n",
       "      <td>0.002569</td>\n",
       "      <td>0.004680</td>\n",
       "      <td>-0.002137</td>\n",
       "      <td>-0.002635</td>\n",
       "      <td>0.001493</td>\n",
       "      <td>-0.002922</td>\n",
       "      <td>-0.000322</td>\n",
       "      <td>-0.001423</td>\n",
       "      <td>0.005636</td>\n",
       "      <td>-0.001817</td>\n",
       "      <td>-0.001013</td>\n",
       "      <td>-0.003184</td>\n",
       "      <td>-0.002559</td>\n",
       "      <td>0.009711</td>\n",
       "      <td>-0.002469</td>\n",
       "      <td>-0.000687</td>\n",
       "      <td>-0.004585</td>\n",
       "      <td>-0.002262</td>\n",
       "      <td>-0.001022</td>\n",
       "      <td>-0.001254</td>\n",
       "      <td>0.001460</td>\n",
       "      <td>-0.001986</td>\n",
       "      <td>0.002875</td>\n",
       "      <td>0.000172</td>\n",
       "      <td>0.005543</td>\n",
       "      <td>-0.002761</td>\n",
       "      <td>-0.004694</td>\n",
       "      <td>0.001504</td>\n",
       "      <td>0.001256</td>\n",
       "      <td>-0.002305</td>\n",
       "      <td>-0.000342</td>\n",
       "      <td>0.005839</td>\n",
       "      <td>-0.000132</td>\n",
       "      <td>0.002023</td>\n",
       "      <td>0.000065</td>\n",
       "      <td>0.002842</td>\n",
       "      <td>0.000172</td>\n",
       "      <td>-0.000641</td>\n",
       "      <td>-0.003277</td>\n",
       "      <td>0.002402</td>\n",
       "      <td>0.001204</td>\n",
       "      <td>0.001047</td>\n",
       "      <td>0.004657</td>\n",
       "      <td>0.004583</td>\n",
       "      <td>0.003967</td>\n",
       "      <td>-0.001267</td>\n",
       "      <td>-0.002492</td>\n",
       "      <td>-0.000786</td>\n",
       "      <td>0.000506</td>\n",
       "      <td>0.004314</td>\n",
       "      <td>0.007555</td>\n",
       "      <td>0.004109</td>\n",
       "      <td>-0.004471</td>\n",
       "      <td>-0.000172</td>\n",
       "      <td>-0.004557</td>\n",
       "      <td>0.004416</td>\n",
       "      <td>-0.003030</td>\n",
       "      <td>0.006550</td>\n",
       "      <td>-0.000294</td>\n",
       "      <td>0.002094</td>\n",
       "      <td>0.000139</td>\n",
       "      <td>-0.001935</td>\n",
       "      <td>-0.002004</td>\n",
       "      <td>0.000801</td>\n",
       "      <td>-0.001115</td>\n",
       "      <td>0.000874</td>\n",
       "      <td>0.001151</td>\n",
       "      <td>-0.005034</td>\n",
       "      <td>-0.004070</td>\n",
       "      <td>-0.000181</td>\n",
       "      <td>0.001080</td>\n",
       "      <td>-0.002773</td>\n",
       "      <td>-0.002241</td>\n",
       "      <td>0.000619</td>\n",
       "      <td>0.000899</td>\n",
       "      <td>0.003798</td>\n",
       "      <td>-0.006009</td>\n",
       "      <td>-0.001476</td>\n",
       "      <td>-0.003195</td>\n",
       "      <td>0.000434</td>\n",
       "      <td>0.000206</td>\n",
       "      <td>0.005530</td>\n",
       "      <td>0.002120</td>\n",
       "      <td>0.001604</td>\n",
       "      <td>-0.005251</td>\n",
       "      <td>-0.002049</td>\n",
       "      <td>0.000679</td>\n",
       "      <td>-0.000616</td>\n",
       "      <td>0.003415</td>\n",
       "      <td>0.001761</td>\n",
       "      <td>-0.008393</td>\n",
       "      <td>-0.005606</td>\n",
       "      <td>-0.004140</td>\n",
       "      <td>-0.002662</td>\n",
       "      <td>0.002551</td>\n",
       "      <td>-0.000123</td>\n",
       "      <td>0.000246</td>\n",
       "      <td>-0.003948</td>\n",
       "      <td>-0.000277</td>\n",
       "      <td>0.008579</td>\n",
       "      <td>-0.003803</td>\n",
       "      <td>-0.002374</td>\n",
       "      <td>-0.003799</td>\n",
       "      <td>-0.001111</td>\n",
       "      <td>0.001898</td>\n",
       "      <td>-0.006589</td>\n",
       "      <td>0.004565</td>\n",
       "      <td>-0.002189</td>\n",
       "      <td>0.000803</td>\n",
       "      <td>0.000402</td>\n",
       "      <td>-0.001357</td>\n",
       "      <td>0.001973</td>\n",
       "      <td>-0.000617</td>\n",
       "      <td>0.001813</td>\n",
       "      <td>-0.000866</td>\n",
       "      <td>0.000793</td>\n",
       "      <td>-0.001070</td>\n",
       "      <td>0.007350</td>\n",
       "      <td>0.001474</td>\n",
       "      <td>0.000579</td>\n",
       "      <td>-0.000975</td>\n",
       "      <td>-0.001479</td>\n",
       "      <td>0.000114</td>\n",
       "      <td>-0.004684</td>\n",
       "      <td>-0.001033</td>\n",
       "      <td>0.001320</td>\n",
       "      <td>-0.001499</td>\n",
       "      <td>0.009720</td>\n",
       "      <td>0.009095</td>\n",
       "      <td>-0.000479</td>\n",
       "      <td>-0.002496</td>\n",
       "      <td>0.005451</td>\n",
       "      <td>-0.002381</td>\n",
       "      <td>-0.006568</td>\n",
       "      <td>0.000818</td>\n",
       "      <td>-0.000777</td>\n",
       "      <td>-0.001941</td>\n",
       "      <td>0.001694</td>\n",
       "      <td>-0.001048</td>\n",
       "      <td>-0.001094</td>\n",
       "      <td>-0.002372</td>\n",
       "      <td>0.003461</td>\n",
       "      <td>0.002125</td>\n",
       "      <td>0.005880</td>\n",
       "      <td>-0.001812</td>\n",
       "      <td>-0.004756</td>\n",
       "      <td>-0.002478</td>\n",
       "      <td>-0.001727</td>\n",
       "      <td>0.000934</td>\n",
       "      <td>-0.002096</td>\n",
       "      <td>0.005320</td>\n",
       "      <td>0.005873</td>\n",
       "      <td>0.001318</td>\n",
       "      <td>0.006239</td>\n",
       "      <td>0.004023</td>\n",
       "      <td>0.002781</td>\n",
       "      <td>0.002124</td>\n",
       "      <td>0.001255</td>\n",
       "      <td>-0.000090</td>\n",
       "      <td>-0.001551</td>\n",
       "      <td>0.004727</td>\n",
       "      <td>-0.001337</td>\n",
       "      <td>-0.003990</td>\n",
       "      <td>-0.001096</td>\n",
       "      <td>0.004467</td>\n",
       "      <td>-0.001238</td>\n",
       "      <td>-0.001964</td>\n",
       "      <td>-0.003978</td>\n",
       "      <td>0.001335</td>\n",
       "      <td>-0.005609</td>\n",
       "      <td>0.001872</td>\n",
       "      <td>0.003155</td>\n",
       "      <td>0.001036</td>\n",
       "      <td>0.002717</td>\n",
       "      <td>0.003748</td>\n",
       "      <td>0.004367</td>\n",
       "      <td>-0.000375</td>\n",
       "      <td>0.006562</td>\n",
       "      <td>-0.002012</td>\n",
       "      <td>-0.003209</td>\n",
       "      <td>0.000956</td>\n",
       "      <td>0.002024</td>\n",
       "      <td>-0.004570</td>\n",
       "      <td>-0.002332</td>\n",
       "      <td>0.001395</td>\n",
       "      <td>-0.006333</td>\n",
       "      <td>-0.000461</td>\n",
       "      <td>-0.000622</td>\n",
       "      <td>0.001335</td>\n",
       "      <td>-0.003008</td>\n",
       "      <td>0.003822</td>\n",
       "      <td>-0.002796</td>\n",
       "      <td>0.007153</td>\n",
       "      <td>0.004183</td>\n",
       "      <td>-0.001526</td>\n",
       "      <td>-0.000269</td>\n",
       "      <td>-0.002673</td>\n",
       "      <td>-0.000539</td>\n",
       "      <td>-0.000320</td>\n",
       "      <td>0.001280</td>\n",
       "      <td>0.002303</td>\n",
       "      <td>0.000291</td>\n",
       "      <td>-0.000373</td>\n",
       "      <td>-0.000196</td>\n",
       "      <td>0.004313</td>\n",
       "      <td>0.000826</td>\n",
       "      <td>-0.000952</td>\n",
       "      <td>-0.003979</td>\n",
       "      <td>-0.004870</td>\n",
       "      <td>-0.001522</td>\n",
       "      <td>0.001179</td>\n",
       "      <td>-0.005555</td>\n",
       "      <td>0.001200</td>\n",
       "      <td>0.001377</td>\n",
       "      <td>0.001342</td>\n",
       "      <td>-0.003245</td>\n",
       "      <td>-0.001757</td>\n",
       "      <td>-0.002752</td>\n",
       "      <td>-0.002166</td>\n",
       "      <td>0.001909</td>\n",
       "      <td>-0.000906</td>\n",
       "      <td>-0.000389</td>\n",
       "      <td>0.006970</td>\n",
       "      <td>-0.003770</td>\n",
       "      <td>-0.001061</td>\n",
       "      <td>-0.003503</td>\n",
       "      <td>0.000451</td>\n",
       "      <td>-0.004818</td>\n",
       "      <td>-0.000680</td>\n",
       "      <td>0.000683</td>\n",
       "      <td>-0.000096</td>\n",
       "      <td>-0.002419</td>\n",
       "      <td>-0.001234</td>\n",
       "      <td>0.002338</td>\n",
       "      <td>0.002906</td>\n",
       "      <td>0.000481</td>\n",
       "      <td>0.001984</td>\n",
       "      <td>-0.003525</td>\n",
       "      <td>0.003165</td>\n",
       "      <td>0.001038</td>\n",
       "      <td>0.003255</td>\n",
       "      <td>0.006741</td>\n",
       "      <td>0.002472</td>\n",
       "      <td>-0.001210</td>\n",
       "      <td>-0.007175</td>\n",
       "      <td>-0.002119</td>\n",
       "      <td>0.001217</td>\n",
       "      <td>0.000504</td>\n",
       "      <td>0.004485</td>\n",
       "      <td>0.001275</td>\n",
       "      <td>-0.000142</td>\n",
       "      <td>-0.004031</td>\n",
       "      <td>-0.000503</td>\n",
       "      <td>-0.000118</td>\n",
       "      <td>-0.000904</td>\n",
       "      <td>0.002443</td>\n",
       "      <td>0.001480</td>\n",
       "      <td>-0.005658</td>\n",
       "      <td>0.001009</td>\n",
       "      <td>0.001477</td>\n",
       "      <td>0.000032</td>\n",
       "      <td>-0.000121</td>\n",
       "      <td>-0.000269</td>\n",
       "      <td>0.005380</td>\n",
       "      <td>-0.001908</td>\n",
       "      <td>-0.001715</td>\n",
       "      <td>0.004143</td>\n",
       "      <td>-0.001303</td>\n",
       "      <td>0.001102</td>\n",
       "      <td>0.002327</td>\n",
       "      <td>-0.003759</td>\n",
       "      <td>0.000230</td>\n",
       "      <td>0.002489</td>\n",
       "      <td>0.000010</td>\n",
       "      <td>0.000424</td>\n",
       "      <td>-0.003173</td>\n",
       "      <td>-0.002612</td>\n",
       "      <td>-0.000615</td>\n",
       "      <td>0.001966</td>\n",
       "      <td>-0.004159</td>\n",
       "      <td>0.000836</td>\n",
       "      <td>0.002072</td>\n",
       "      <td>0.001258</td>\n",
       "      <td>-0.001389</td>\n",
       "      <td>0.001128</td>\n",
       "      <td>-0.000521</td>\n",
       "      <td>-0.001216</td>\n",
       "      <td>0.002973</td>\n",
       "      <td>0.003403</td>\n",
       "      <td>0.001669</td>\n",
       "      <td>-0.000864</td>\n",
       "      <td>0.002378</td>\n",
       "      <td>0.000054</td>\n",
       "      <td>0.001301</td>\n",
       "      <td>-0.004092</td>\n",
       "      <td>0.001429</td>\n",
       "      <td>-0.002743</td>\n",
       "      <td>0.000202</td>\n",
       "      <td>-0.000045</td>\n",
       "      <td>0.007586</td>\n",
       "      <td>0.001942</td>\n",
       "      <td>-0.002954</td>\n",
       "      <td>0.002352</td>\n",
       "      <td>-0.000481</td>\n",
       "      <td>-0.003557</td>\n",
       "      <td>-0.005077</td>\n",
       "      <td>-0.002971</td>\n",
       "      <td>-0.002590</td>\n",
       "      <td>-0.002069</td>\n",
       "      <td>-0.000475</td>\n",
       "      <td>0.001308</td>\n",
       "      <td>0.004418</td>\n",
       "      <td>0.003743</td>\n",
       "      <td>-0.000926</td>\n",
       "      <td>-0.001580</td>\n",
       "      <td>-0.003231</td>\n",
       "      <td>0.001507</td>\n",
       "      <td>-0.001637</td>\n",
       "      <td>0.000145</td>\n",
       "      <td>0.001127</td>\n",
       "      <td>0.004555</td>\n",
       "      <td>0.001480</td>\n",
       "      <td>0.002754</td>\n",
       "      <td>-0.000601</td>\n",
       "      <td>-0.000234</td>\n",
       "      <td>0.002108</td>\n",
       "      <td>0.006276</td>\n",
       "      <td>0.007515</td>\n",
       "      <td>-0.001051</td>\n",
       "      <td>0.003448</td>\n",
       "      <td>-0.000997</td>\n",
       "      <td>0.002500</td>\n",
       "      <td>0.003340</td>\n",
       "      <td>-0.000701</td>\n",
       "      <td>-0.002149</td>\n",
       "      <td>0.002387</td>\n",
       "      <td>0.000185</td>\n",
       "      <td>0.003405</td>\n",
       "      <td>0.000774</td>\n",
       "      <td>0.002302</td>\n",
       "      <td>0.000405</td>\n",
       "      <td>-0.002441</td>\n",
       "      <td>-0.004189</td>\n",
       "      <td>-0.006633</td>\n",
       "      <td>-0.001021</td>\n",
       "      <td>0.000057</td>\n",
       "      <td>0.003429</td>\n",
       "      <td>0.004212</td>\n",
       "      <td>0.006550</td>\n",
       "      <td>0.005122</td>\n",
       "      <td>0.000868</td>\n",
       "      <td>-0.000535</td>\n",
       "      <td>0.001214</td>\n",
       "      <td>0.003614</td>\n",
       "      <td>-0.002960</td>\n",
       "      <td>0.003009</td>\n",
       "      <td>0.004533</td>\n",
       "      <td>-0.001410</td>\n",
       "      <td>0.001783</td>\n",
       "      <td>0.003561</td>\n",
       "      <td>0.002296</td>\n",
       "      <td>-0.005875</td>\n",
       "      <td>0.004130</td>\n",
       "      <td>-0.000021</td>\n",
       "      <td>0.002359</td>\n",
       "      <td>0.000964</td>\n",
       "      <td>-0.002601</td>\n",
       "      <td>0.001525</td>\n",
       "      <td>-0.003411</td>\n",
       "      <td>0.002889</td>\n",
       "      <td>-0.001738</td>\n",
       "      <td>0.001603</td>\n",
       "      <td>0.004800</td>\n",
       "      <td>0.001794</td>\n",
       "      <td>0.001562</td>\n",
       "      <td>0.003128</td>\n",
       "      <td>0.002610</td>\n",
       "      <td>0.003382</td>\n",
       "      <td>-0.002742</td>\n",
       "      <td>0.000425</td>\n",
       "      <td>-0.001814</td>\n",
       "      <td>0.000590</td>\n",
       "      <td>0.004957</td>\n",
       "      <td>0.004323</td>\n",
       "      <td>-0.000667</td>\n",
       "      <td>-0.001308</td>\n",
       "      <td>0.004177</td>\n",
       "      <td>0.005218</td>\n",
       "      <td>-0.004517</td>\n",
       "      <td>-0.001381</td>\n",
       "      <td>0.001946</td>\n",
       "      <td>-0.000935</td>\n",
       "      <td>-0.000384</td>\n",
       "      <td>0.005522</td>\n",
       "      <td>0.001916</td>\n",
       "      <td>-0.000224</td>\n",
       "      <td>-0.001612</td>\n",
       "      <td>0.000215</td>\n",
       "      <td>-0.003706</td>\n",
       "      <td>-0.004424</td>\n",
       "      <td>0.003279</td>\n",
       "      <td>0.000249</td>\n",
       "      <td>-0.000537</td>\n",
       "      <td>0.002109</td>\n",
       "      <td>-0.002996</td>\n",
       "      <td>0.005084</td>\n",
       "      <td>-0.001674</td>\n",
       "      <td>0.002071</td>\n",
       "      <td>-0.000332</td>\n",
       "      <td>0.002586</td>\n",
       "      <td>0.004121</td>\n",
       "      <td>-0.004687</td>\n",
       "      <td>0.003246</td>\n",
       "      <td>-0.001835</td>\n",
       "      <td>-0.001675</td>\n",
       "      <td>0.001736</td>\n",
       "      <td>0.000093</td>\n",
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       "      <td>-0.001572</td>\n",
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       "      <td>-0.004282</td>\n",
       "      <td>-0.010399</td>\n",
       "      <td>-0.012962</td>\n",
       "      <td>-0.003479</td>\n",
       "      <td>-0.002665</td>\n",
       "      <td>-0.006844</td>\n",
       "      <td>-0.002174</td>\n",
       "      <td>0.003723</td>\n",
       "      <td>-0.000374</td>\n",
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       "      <td>-0.002583</td>\n",
       "      <td>0.008642</td>\n",
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       "      <td>0.004081</td>\n",
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       "      <td>0.001104</td>\n",
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       "      <td>-0.003889</td>\n",
       "      <td>0.006800</td>\n",
       "      <td>-0.000453</td>\n",
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       "      <td>-0.003426</td>\n",
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       "      <td>-0.001730</td>\n",
       "      <td>-0.009898</td>\n",
       "      <td>0.008350</td>\n",
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       "      <td>-0.000954</td>\n",
       "      <td>-0.001176</td>\n",
       "      <td>-0.007818</td>\n",
       "      <td>0.006224</td>\n",
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       "      <td>0.001134</td>\n",
       "      <td>0.000671</td>\n",
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       "      <td>0.007090</td>\n",
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       "      <td>0.000294</td>\n",
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       "      <td>0.000835</td>\n",
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       "      <td>-0.000602</td>\n",
       "      <td>0.003235</td>\n",
       "      <td>-0.002165</td>\n",
       "      <td>-0.000303</td>\n",
       "      <td>0.006226</td>\n",
       "      <td>-0.007822</td>\n",
       "      <td>0.009467</td>\n",
       "      <td>-0.006166</td>\n",
       "      <td>-0.010602</td>\n",
       "      <td>0.002417</td>\n",
       "      <td>-0.007640</td>\n",
       "      <td>0.001239</td>\n",
       "      <td>0.011710</td>\n",
       "      <td>0.001674</td>\n",
       "      <td>-0.009277</td>\n",
       "      <td>0.018129</td>\n",
       "      <td>-0.000277</td>\n",
       "      <td>0.002837</td>\n",
       "      <td>0.010907</td>\n",
       "      <td>-0.000019</td>\n",
       "      <td>-0.007891</td>\n",
       "      <td>-0.000513</td>\n",
       "      <td>-0.005164</td>\n",
       "      <td>-0.009073</td>\n",
       "      <td>0.006254</td>\n",
       "      <td>-0.004111</td>\n",
       "      <td>0.001554</td>\n",
       "      <td>-0.004333</td>\n",
       "      <td>0.004080</td>\n",
       "      <td>-0.000377</td>\n",
       "      <td>-0.003770</td>\n",
       "      <td>-0.008022</td>\n",
       "      <td>0.001184</td>\n",
       "      <td>0.003038</td>\n",
       "      <td>0.001468</td>\n",
       "      <td>-0.000879</td>\n",
       "      <td>-0.000320</td>\n",
       "      <td>-0.003316</td>\n",
       "      <td>-0.004705</td>\n",
       "      <td>0.003219</td>\n",
       "      <td>0.010647</td>\n",
       "      <td>-0.005367</td>\n",
       "      <td>0.000033</td>\n",
       "      <td>-0.004668</td>\n",
       "      <td>-0.000954</td>\n",
       "      <td>0.000659</td>\n",
       "      <td>-0.009368</td>\n",
       "      <td>0.004869</td>\n",
       "      <td>-0.007203</td>\n",
       "      <td>-0.002377</td>\n",
       "      <td>0.005307</td>\n",
       "      <td>0.001868</td>\n",
       "      <td>0.000336</td>\n",
       "      <td>-0.005962</td>\n",
       "      <td>0.002682</td>\n",
       "      <td>0.011439</td>\n",
       "      <td>-0.000544</td>\n",
       "      <td>-0.006361</td>\n",
       "      <td>0.002187</td>\n",
       "      <td>-0.007299</td>\n",
       "      <td>0.000906</td>\n",
       "      <td>-0.009517</td>\n",
       "      <td>0.005618</td>\n",
       "      <td>0.003141</td>\n",
       "      <td>0.003059</td>\n",
       "      <td>-0.009328</td>\n",
       "      <td>0.001501</td>\n",
       "      <td>-0.006116</td>\n",
       "      <td>0.006799</td>\n",
       "      <td>0.013723</td>\n",
       "      <td>-0.001735</td>\n",
       "      <td>0.001315</td>\n",
       "      <td>-0.001019</td>\n",
       "      <td>-0.002113</td>\n",
       "      <td>0.005620</td>\n",
       "      <td>0.004252</td>\n",
       "      <td>-0.003208</td>\n",
       "      <td>0.008023</td>\n",
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       "      <td>-0.001190</td>\n",
       "      <td>0.003499</td>\n",
       "      <td>-0.002710</td>\n",
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       "      <td>0.013966</td>\n",
       "      <td>-0.004433</td>\n",
       "      <td>-0.000767</td>\n",
       "      <td>-0.000362</td>\n",
       "      <td>-0.003351</td>\n",
       "      <td>-0.005110</td>\n",
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       "      <td>0.001814</td>\n",
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       "      <td>0.009630</td>\n",
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       "      <td>0.013950</td>\n",
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       "      <td>-0.005467</td>\n",
       "      <td>0.015710</td>\n",
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       "      <td>-0.009304</td>\n",
       "      <td>-0.004565</td>\n",
       "      <td>0.006165</td>\n",
       "      <td>0.005684</td>\n",
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       "      <td>0.001306</td>\n",
       "      <td>-0.001641</td>\n",
       "      <td>0.002236</td>\n",
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       "      <td>0.002357</td>\n",
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       "      <td>0.000343</td>\n",
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       "      <td>-0.003499</td>\n",
       "      <td>-0.000623</td>\n",
       "      <td>0.001454</td>\n",
       "      <td>0.006903</td>\n",
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       "      <td>0.008498</td>\n",
       "      <td>-0.014401</td>\n",
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       "      <td>0.003366</td>\n",
       "      <td>-0.005883</td>\n",
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       "      <td>-0.006486</td>\n",
       "      <td>-0.000705</td>\n",
       "      <td>-0.000750</td>\n",
       "      <td>0.005155</td>\n",
       "      <td>0.000965</td>\n",
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       "      <td>0.014078</td>\n",
       "      <td>0.001400</td>\n",
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       "      <td>0.005291</td>\n",
       "      <td>-0.000217</td>\n",
       "      <td>-0.002394</td>\n",
       "      <td>-0.001999</td>\n",
       "      <td>0.005366</td>\n",
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       "      <td>-0.009055</td>\n",
       "      <td>-0.014639</td>\n",
       "      <td>0.000942</td>\n",
       "      <td>0.006496</td>\n",
       "      <td>0.003931</td>\n",
       "      <td>0.000031</td>\n",
       "      <td>0.005376</td>\n",
       "      <td>0.002595</td>\n",
       "      <td>-0.002620</td>\n",
       "      <td>-0.002217</td>\n",
       "      <td>0.005306</td>\n",
       "      <td>0.002845</td>\n",
       "      <td>0.004135</td>\n",
       "      <td>-0.009981</td>\n",
       "      <td>-0.015908</td>\n",
       "      <td>0.000012</td>\n",
       "      <td>-0.010344</td>\n",
       "      <td>-0.002937</td>\n",
       "      <td>-0.006903</td>\n",
       "      <td>-0.005679</td>\n",
       "      <td>-0.001248</td>\n",
       "      <td>0.001291</td>\n",
       "      <td>0.003133</td>\n",
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       "      <td>-0.001722</td>\n",
       "      <td>-0.002306</td>\n",
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       "      <td>-0.011160</td>\n",
       "      <td>-0.002319</td>\n",
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       "      <td>-0.000613</td>\n",
       "      <td>-0.004740</td>\n",
       "      <td>-0.005228</td>\n",
       "      <td>-0.006163</td>\n",
       "      <td>-0.004335</td>\n",
       "      <td>-0.002118</td>\n",
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       "      <td>0.010316</td>\n",
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       "      <td>-0.002700</td>\n",
       "      <td>-0.001127</td>\n",
       "      <td>-0.001774</td>\n",
       "      <td>0.002004</td>\n",
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       "      <td>-0.000777</td>\n",
       "      <td>0.003470</td>\n",
       "      <td>-0.008865</td>\n",
       "      <td>-0.007892</td>\n",
       "      <td>-0.003874</td>\n",
       "      <td>0.005461</td>\n",
       "      <td>-0.001200</td>\n",
       "      <td>0.004115</td>\n",
       "      <td>0.003855</td>\n",
       "      <td>0.004767</td>\n",
       "      <td>0.006461</td>\n",
       "      <td>0.000979</td>\n",
       "      <td>0.008012</td>\n",
       "      <td>0.002827</td>\n",
       "      <td>0.006030</td>\n",
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       "      <td>-0.000727</td>\n",
       "      <td>0.008595</td>\n",
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       "      <td>-0.000301</td>\n",
       "      <td>-0.009865</td>\n",
       "      <td>0.001483</td>\n",
       "      <td>-0.004066</td>\n",
       "      <td>-0.002139</td>\n",
       "      <td>-0.004218</td>\n",
       "      <td>0.001802</td>\n",
       "      <td>-0.002987</td>\n",
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       "      <td>-0.002728</td>\n",
       "      <td>-0.006267</td>\n",
       "      <td>-0.010614</td>\n",
       "      <td>-0.001046</td>\n",
       "      <td>0.006791</td>\n",
       "      <td>0.004493</td>\n",
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       "      <td>0.002660</td>\n",
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       "      <td>-0.007306</td>\n",
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       "      <td>-0.000642</td>\n",
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       "      <td>0.006323</td>\n",
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       "      <td>-0.006554</td>\n",
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       "      <td>-0.004796</td>\n",
       "      <td>0.002849</td>\n",
       "      <td>-0.001765</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.012552</td>\n",
       "      <td>0.000978</td>\n",
       "      <td>0.000258</td>\n",
       "      <td>0.002048</td>\n",
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       "      <td>-0.007890</td>\n",
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       "      <td>-0.004785</td>\n",
       "      <td>0.000367</td>\n",
       "      <td>-0.006203</td>\n",
       "      <td>-0.001429</td>\n",
       "      <td>-0.001482</td>\n",
       "      <td>-0.010280</td>\n",
       "      <td>-0.005736</td>\n",
       "      <td>0.003152</td>\n",
       "      <td>0.000891</td>\n",
       "      <td>0.004027</td>\n",
       "      <td>-0.005992</td>\n",
       "      <td>0.012622</td>\n",
       "      <td>0.001295</td>\n",
       "      <td>0.002236</td>\n",
       "      <td>-0.003848</td>\n",
       "      <td>-0.011573</td>\n",
       "      <td>-0.001941</td>\n",
       "      <td>-0.001491</td>\n",
       "      <td>-0.002082</td>\n",
       "      <td>-0.001376</td>\n",
       "      <td>0.012701</td>\n",
       "      <td>-0.004406</td>\n",
       "      <td>-0.001867</td>\n",
       "      <td>-0.007065</td>\n",
       "      <td>-0.013587</td>\n",
       "      <td>-0.006844</td>\n",
       "      <td>0.004582</td>\n",
       "      <td>0.004665</td>\n",
       "      <td>0.003250</td>\n",
       "      <td>0.001550</td>\n",
       "      <td>-0.002634</td>\n",
       "      <td>-0.000942</td>\n",
       "      <td>-0.003904</td>\n",
       "      <td>0.008197</td>\n",
       "      <td>-0.006898</td>\n",
       "      <td>0.001222</td>\n",
       "      <td>-0.002718</td>\n",
       "      <td>0.004297</td>\n",
       "      <td>0.002277</td>\n",
       "      <td>-0.002550</td>\n",
       "      <td>-0.018845</td>\n",
       "      <td>0.000523</td>\n",
       "      <td>-0.003671</td>\n",
       "      <td>-0.010317</td>\n",
       "      <td>-0.005334</td>\n",
       "      <td>-0.001465</td>\n",
       "      <td>-0.005947</td>\n",
       "      <td>0.006385</td>\n",
       "      <td>0.004098</td>\n",
       "      <td>0.003143</td>\n",
       "      <td>-0.007337</td>\n",
       "      <td>0.003075</td>\n",
       "      <td>-0.008057</td>\n",
       "      <td>-0.005565</td>\n",
       "      <td>-0.060697</td>\n",
       "      <td>-0.003229</td>\n",
       "      <td>-0.006064</td>\n",
       "      <td>-0.003188</td>\n",
       "      <td>0.004351</td>\n",
       "      <td>0.000999</td>\n",
       "      <td>-0.003024</td>\n",
       "      <td>0.009441</td>\n",
       "      <td>0.004138</td>\n",
       "      <td>0.001603</td>\n",
       "      <td>0.004168</td>\n",
       "      <td>-0.001501</td>\n",
       "      <td>-0.002240</td>\n",
       "      <td>-0.002617</td>\n",
       "      <td>-0.007572</td>\n",
       "      <td>-0.004837</td>\n",
       "      <td>-0.002979</td>\n",
       "      <td>0.008550</td>\n",
       "      <td>0.007910</td>\n",
       "      <td>-0.008430</td>\n",
       "      <td>-0.009190</td>\n",
       "      <td>-0.015501</td>\n",
       "      <td>-0.007483</td>\n",
       "      <td>-0.002947</td>\n",
       "      <td>-0.003342</td>\n",
       "      <td>-0.002443</td>\n",
       "      <td>0.011828</td>\n",
       "      <td>0.001698</td>\n",
       "      <td>0.011475</td>\n",
       "      <td>0.008131</td>\n",
       "      <td>0.006325</td>\n",
       "      <td>-0.002210</td>\n",
       "      <td>-0.004297</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>0.004262</td>\n",
       "      <td>0.012264</td>\n",
       "      <td>-0.006074</td>\n",
       "      <td>0.003066</td>\n",
       "      <td>0.010232</td>\n",
       "      <td>0.005343</td>\n",
       "      <td>0.003184</td>\n",
       "      <td>0.000282</td>\n",
       "      <td>0.001695</td>\n",
       "      <td>-0.001385</td>\n",
       "      <td>-0.004533</td>\n",
       "      <td>-0.004097</td>\n",
       "      <td>0.006333</td>\n",
       "      <td>0.005412</td>\n",
       "      <td>-0.005033</td>\n",
       "      <td>-0.007391</td>\n",
       "      <td>-0.005897</td>\n",
       "      <td>-0.002225</td>\n",
       "      <td>-0.004812</td>\n",
       "      <td>-0.005262</td>\n",
       "      <td>0.012048</td>\n",
       "      <td>-0.005728</td>\n",
       "      <td>-0.007392</td>\n",
       "      <td>-0.008579</td>\n",
       "      <td>0.006233</td>\n",
       "      <td>-0.005056</td>\n",
       "      <td>0.006742</td>\n",
       "      <td>0.005189</td>\n",
       "      <td>0.000417</td>\n",
       "      <td>-0.008313</td>\n",
       "      <td>-0.007317</td>\n",
       "      <td>0.006115</td>\n",
       "      <td>0.005129</td>\n",
       "      <td>-0.002841</td>\n",
       "      <td>-0.000614</td>\n",
       "      <td>-0.007128</td>\n",
       "      <td>0.011599</td>\n",
       "      <td>0.008932</td>\n",
       "      <td>-0.011903</td>\n",
       "      <td>0.005094</td>\n",
       "      <td>0.000661</td>\n",
       "      <td>0.004745</td>\n",
       "      <td>-0.003011</td>\n",
       "      <td>-0.005974</td>\n",
       "      <td>0.007307</td>\n",
       "      <td>0.001578</td>\n",
       "      <td>-0.008151</td>\n",
       "      <td>0.005671</td>\n",
       "      <td>0.004066</td>\n",
       "      <td>-0.006707</td>\n",
       "      <td>-0.002241</td>\n",
       "      <td>-0.006532</td>\n",
       "      <td>0.004787</td>\n",
       "      <td>0.001448</td>\n",
       "      <td>0.002488</td>\n",
       "      <td>-0.000586</td>\n",
       "      <td>-0.003469</td>\n",
       "      <td>-0.004990</td>\n",
       "      <td>0.002304</td>\n",
       "      <td>0.009995</td>\n",
       "      <td>-0.011101</td>\n",
       "      <td>0.007077</td>\n",
       "      <td>-0.004715</td>\n",
       "      <td>0.007286</td>\n",
       "      <td>-0.002932</td>\n",
       "      <td>-0.000506</td>\n",
       "      <td>-0.009166</td>\n",
       "      <td>0.004778</td>\n",
       "      <td>-0.003077</td>\n",
       "      <td>-0.007048</td>\n",
       "      <td>-0.012998</td>\n",
       "      <td>0.007303</td>\n",
       "      <td>-0.008854</td>\n",
       "      <td>-0.001154</td>\n",
       "      <td>-0.001642</td>\n",
       "      <td>-0.003245</td>\n",
       "      <td>-0.002352</td>\n",
       "      <td>0.002716</td>\n",
       "      <td>0.001694</td>\n",
       "      <td>0.002737</td>\n",
       "      <td>0.006903</td>\n",
       "      <td>-0.025161</td>\n",
       "      <td>0.000656</td>\n",
       "      <td>0.005195</td>\n",
       "      <td>-0.002560</td>\n",
       "      <td>0.000402</td>\n",
       "      <td>0.003565</td>\n",
       "      <td>-0.005294</td>\n",
       "      <td>-0.001042</td>\n",
       "      <td>-0.003891</td>\n",
       "      <td>0.001385</td>\n",
       "      <td>-0.005814</td>\n",
       "      <td>-0.002445</td>\n",
       "      <td>0.007236</td>\n",
       "      <td>0.005015</td>\n",
       "      <td>-0.009967</td>\n",
       "      <td>-0.000970</td>\n",
       "      <td>0.002171</td>\n",
       "      <td>-0.004240</td>\n",
       "      <td>0.003099</td>\n",
       "      <td>0.001778</td>\n",
       "      <td>0.002112</td>\n",
       "      <td>0.001868</td>\n",
       "      <td>0.008177</td>\n",
       "      <td>0.009051</td>\n",
       "      <td>0.005942</td>\n",
       "      <td>-0.000101</td>\n",
       "      <td>-0.000157</td>\n",
       "      <td>-0.011027</td>\n",
       "      <td>-0.001329</td>\n",
       "      <td>-0.008444</td>\n",
       "      <td>-0.006795</td>\n",
       "      <td>-0.002029</td>\n",
       "      <td>0.006345</td>\n",
       "      <td>-0.010165</td>\n",
       "      <td>-0.011244</td>\n",
       "      <td>0.003346</td>\n",
       "      <td>0.001837</td>\n",
       "      <td>0.000283</td>\n",
       "      <td>-0.004299</td>\n",
       "      <td>-0.008879</td>\n",
       "      <td>-0.005314</td>\n",
       "      <td>0.005435</td>\n",
       "      <td>0.010013</td>\n",
       "      <td>-0.003408</td>\n",
       "      <td>-0.011762</td>\n",
       "      <td>0.003980</td>\n",
       "      <td>0.002708</td>\n",
       "      <td>0.011329</td>\n",
       "      <td>-0.006497</td>\n",
       "      <td>-0.009053</td>\n",
       "      <td>0.002202</td>\n",
       "      <td>-0.003057</td>\n",
       "      <td>0.007133</td>\n",
       "      <td>0.003445</td>\n",
       "      <td>0.004320</td>\n",
       "      <td>0.002970</td>\n",
       "      <td>0.003383</td>\n",
       "      <td>-0.003527</td>\n",
       "      <td>0.003751</td>\n",
       "      <td>-0.003493</td>\n",
       "      <td>-0.000049</td>\n",
       "      <td>-0.001987</td>\n",
       "      <td>-0.000017</td>\n",
       "      <td>-0.005411</td>\n",
       "      <td>0.006548</td>\n",
       "      <td>0.008914</td>\n",
       "      <td>0.000638</td>\n",
       "      <td>-0.012132</td>\n",
       "      <td>-0.004102</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>-0.012850</td>\n",
       "      <td>-0.000442</td>\n",
       "      <td>-0.003732</td>\n",
       "      <td>-0.000119</td>\n",
       "      <td>-0.012227</td>\n",
       "      <td>0.004068</td>\n",
       "      <td>-0.001276</td>\n",
       "      <td>0.000127</td>\n",
       "      <td>-0.001520</td>\n",
       "      <td>0.000678</td>\n",
       "      <td>-0.002492</td>\n",
       "      <td>-0.000337</td>\n",
       "      <td>0.014066</td>\n",
       "      <td>0.014473</td>\n",
       "      <td>-0.003179</td>\n",
       "      <td>0.002331</td>\n",
       "      <td>0.005427</td>\n",
       "      <td>0.005804</td>\n",
       "      <td>-0.007106</td>\n",
       "      <td>0.004689</td>\n",
       "      <td>-0.004587</td>\n",
       "      <td>0.003233</td>\n",
       "      <td>0.000664</td>\n",
       "      <td>0.003754</td>\n",
       "      <td>-0.000662</td>\n",
       "      <td>-0.010687</td>\n",
       "      <td>-0.006939</td>\n",
       "      <td>0.001018</td>\n",
       "      <td>0.001963</td>\n",
       "      <td>0.001727</td>\n",
       "      <td>0.004623</td>\n",
       "      <td>0.008472</td>\n",
       "      <td>0.010430</td>\n",
       "      <td>0.003693</td>\n",
       "      <td>0.008233</td>\n",
       "      <td>0.002822</td>\n",
       "      <td>0.000969</td>\n",
       "      <td>0.001984</td>\n",
       "      <td>-0.001801</td>\n",
       "      <td>-0.001586</td>\n",
       "      <td>0.006529</td>\n",
       "      <td>-0.002727</td>\n",
       "      <td>0.001704</td>\n",
       "      <td>0.000540</td>\n",
       "      <td>-0.001175</td>\n",
       "      <td>0.005885</td>\n",
       "      <td>-0.003644</td>\n",
       "      <td>-0.008909</td>\n",
       "      <td>0.000958</td>\n",
       "      <td>0.004460</td>\n",
       "      <td>0.001717</td>\n",
       "      <td>-0.001592</td>\n",
       "      <td>-0.006151</td>\n",
       "      <td>-0.010675</td>\n",
       "      <td>0.002133</td>\n",
       "      <td>-0.001019</td>\n",
       "      <td>-0.002263</td>\n",
       "      <td>-0.000294</td>\n",
       "      <td>0.003619</td>\n",
       "      <td>0.009191</td>\n",
       "      <td>0.001704</td>\n",
       "      <td>0.001547</td>\n",
       "      <td>-0.003768</td>\n",
       "      <td>-0.011128</td>\n",
       "      <td>-0.009417</td>\n",
       "      <td>-0.006439</td>\n",
       "      <td>0.007931</td>\n",
       "      <td>-0.000818</td>\n",
       "      <td>-0.005343</td>\n",
       "      <td>-0.008997</td>\n",
       "      <td>0.003909</td>\n",
       "      <td>0.001425</td>\n",
       "      <td>-0.002152</td>\n",
       "      <td>-0.008057</td>\n",
       "      <td>0.014025</td>\n",
       "      <td>0.003022</td>\n",
       "      <td>-0.009233</td>\n",
       "      <td>-0.001361</td>\n",
       "      <td>-0.000651</td>\n",
       "      <td>0.000772</td>\n",
       "      <td>-0.003992</td>\n",
       "      <td>-0.014725</td>\n",
       "      <td>-0.000488</td>\n",
       "      <td>0.006974</td>\n",
       "      <td>0.006879</td>\n",
       "      <td>0.003609</td>\n",
       "      <td>-0.003564</td>\n",
       "      <td>-0.006680</td>\n",
       "      <td>-0.010997</td>\n",
       "      <td>0.007559</td>\n",
       "      <td>0.010159</td>\n",
       "      <td>-0.014733</td>\n",
       "      <td>-0.005178</td>\n",
       "      <td>-0.002334</td>\n",
       "      <td>0.002530</td>\n",
       "      <td>-0.004719</td>\n",
       "      <td>0.007352</td>\n",
       "      <td>0.001532</td>\n",
       "      <td>0.001519</td>\n",
       "      <td>0.047338</td>\n",
       "      <td>0.007391</td>\n",
       "      <td>-0.002663</td>\n",
       "      <td>0.000920</td>\n",
       "      <td>-0.004650</td>\n",
       "      <td>0.005127</td>\n",
       "      <td>0.005086</td>\n",
       "      <td>-0.002160</td>\n",
       "      <td>0.000678</td>\n",
       "      <td>0.002952</td>\n",
       "      <td>-0.003636</td>\n",
       "      <td>-0.013328</td>\n",
       "      <td>-0.007709</td>\n",
       "      <td>0.004569</td>\n",
       "      <td>-0.002575</td>\n",
       "      <td>-0.000972</td>\n",
       "      <td>-0.002029</td>\n",
       "      <td>0.003153</td>\n",
       "      <td>0.002792</td>\n",
       "      <td>-0.016595</td>\n",
       "      <td>0.002479</td>\n",
       "      <td>-0.004988</td>\n",
       "      <td>-0.003415</td>\n",
       "      <td>0.013394</td>\n",
       "      <td>-0.006537</td>\n",
       "      <td>0.009334</td>\n",
       "      <td>-0.000333</td>\n",
       "      <td>-0.006531</td>\n",
       "      <td>-0.000129</td>\n",
       "      <td>-0.007381</td>\n",
       "      <td>0.003210</td>\n",
       "      <td>0.000904</td>\n",
       "      <td>0.002817</td>\n",
       "      <td>-0.000622</td>\n",
       "      <td>0.000173</td>\n",
       "      <td>0.011426</td>\n",
       "      <td>-0.003281</td>\n",
       "      <td>0.000395</td>\n",
       "      <td>-0.004874</td>\n",
       "      <td>-0.006136</td>\n",
       "      <td>0.009547</td>\n",
       "      <td>0.008051</td>\n",
       "      <td>-0.001626</td>\n",
       "      <td>0.003418</td>\n",
       "      <td>-0.000933</td>\n",
       "      <td>0.003483</td>\n",
       "      <td>-0.010502</td>\n",
       "      <td>0.002214</td>\n",
       "      <td>0.000709</td>\n",
       "      <td>-0.005218</td>\n",
       "      <td>-0.002550</td>\n",
       "      <td>0.004289</td>\n",
       "      <td>-0.004681</td>\n",
       "      <td>0.008191</td>\n",
       "      <td>-0.000144</td>\n",
       "      <td>0.005022</td>\n",
       "      <td>-0.001442</td>\n",
       "      <td>-0.001293</td>\n",
       "      <td>0.004816</td>\n",
       "      <td>-0.006809</td>\n",
       "      <td>0.009081</td>\n",
       "      <td>0.000935</td>\n",
       "      <td>0.010252</td>\n",
       "      <td>0.009133</td>\n",
       "      <td>-0.004256</td>\n",
       "      <td>0.003006</td>\n",
       "      <td>-0.009026</td>\n",
       "      <td>-0.006350</td>\n",
       "      <td>-0.001395</td>\n",
       "      <td>0.006454</td>\n",
       "      <td>0.007711</td>\n",
       "      <td>-0.001591</td>\n",
       "      <td>0.016419</td>\n",
       "      <td>-0.001153</td>\n",
       "      <td>0.005786</td>\n",
       "      <td>0.005464</td>\n",
       "      <td>0.003176</td>\n",
       "      <td>0.010693</td>\n",
       "      <td>-0.006413</td>\n",
       "      <td>0.006440</td>\n",
       "      <td>0.004761</td>\n",
       "      <td>-0.003553</td>\n",
       "      <td>-0.003816</td>\n",
       "      <td>-0.005992</td>\n",
       "      <td>-0.011989</td>\n",
       "      <td>0.000153</td>\n",
       "      <td>-0.007802</td>\n",
       "      <td>-0.003251</td>\n",
       "      <td>0.000431</td>\n",
       "      <td>-0.001739</td>\n",
       "      <td>0.002278</td>\n",
       "      <td>-0.006634</td>\n",
       "      <td>-0.003393</td>\n",
       "      <td>0.000610</td>\n",
       "      <td>-0.000999</td>\n",
       "      <td>0.002795</td>\n",
       "      <td>-0.002429</td>\n",
       "      <td>-0.009753</td>\n",
       "      <td>0.000326</td>\n",
       "      <td>0.000340</td>\n",
       "      <td>0.012413</td>\n",
       "      <td>-0.003375</td>\n",
       "      <td>0.011150</td>\n",
       "      <td>-0.004546</td>\n",
       "      <td>0.002729</td>\n",
       "      <td>-0.001479</td>\n",
       "      <td>0.007811</td>\n",
       "      <td>0.005798</td>\n",
       "      <td>-0.004262</td>\n",
       "      <td>-0.015676</td>\n",
       "      <td>-0.001840</td>\n",
       "      <td>-0.004580</td>\n",
       "      <td>0.003122</td>\n",
       "      <td>-0.008612</td>\n",
       "      <td>-0.006263</td>\n",
       "      <td>-0.000300</td>\n",
       "      <td>-0.000510</td>\n",
       "      <td>0.002007</td>\n",
       "      <td>0.003972</td>\n",
       "      <td>-0.000751</td>\n",
       "      <td>7.0</td>\n",
       "      <td>63</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3729</th>\n",
       "      <td>-0.002724</td>\n",
       "      <td>0.007787</td>\n",
       "      <td>-0.007066</td>\n",
       "      <td>-0.002400</td>\n",
       "      <td>0.009299</td>\n",
       "      <td>0.002487</td>\n",
       "      <td>-0.013997</td>\n",
       "      <td>-0.010191</td>\n",
       "      <td>0.002911</td>\n",
       "      <td>-0.002189</td>\n",
       "      <td>0.001210</td>\n",
       "      <td>-0.001323</td>\n",
       "      <td>0.014294</td>\n",
       "      <td>0.010910</td>\n",
       "      <td>0.000119</td>\n",
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       "      <td>-0.001459</td>\n",
       "      <td>0.010621</td>\n",
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       "      <td>0.004586</td>\n",
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       "      <td>-0.001578</td>\n",
       "      <td>-0.006514</td>\n",
       "      <td>-0.008255</td>\n",
       "      <td>0.000596</td>\n",
       "      <td>-0.002704</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.008311</td>\n",
       "      <td>0.001148</td>\n",
       "      <td>0.004365</td>\n",
       "      <td>0.009697</td>\n",
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       "      <td>-0.010612</td>\n",
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       "      <td>-0.007660</td>\n",
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       "      <td>-0.001112</td>\n",
       "      <td>0.002834</td>\n",
       "      <td>-0.004281</td>\n",
       "      <td>-0.027291</td>\n",
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       "      <td>-0.000519</td>\n",
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       "      <td>-0.005130</td>\n",
       "      <td>-0.005704</td>\n",
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       "      <td>-0.008327</td>\n",
       "      <td>-0.007024</td>\n",
       "      <td>-0.068795</td>\n",
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       "      <td>-0.001817</td>\n",
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       "      <td>0.004546</td>\n",
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       "      <td>-0.008661</td>\n",
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       "      <td>-0.009051</td>\n",
       "      <td>-0.004153</td>\n",
       "      <td>-0.002853</td>\n",
       "      <td>0.006036</td>\n",
       "      <td>0.013923</td>\n",
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       "      <td>0.012420</td>\n",
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       "      <td>-0.007552</td>\n",
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       "      <td>-0.005927</td>\n",
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       "      <td>-0.002760</td>\n",
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       "      <td>-0.007823</td>\n",
       "      <td>-0.003057</td>\n",
       "      <td>-0.016789</td>\n",
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       "      <td>-0.002990</td>\n",
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       "      <td>0.001292</td>\n",
       "      <td>-0.002087</td>\n",
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       "      <td>-0.005601</td>\n",
       "      <td>0.004106</td>\n",
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       "      <td>0.001263</td>\n",
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       "      <td>-0.002918</td>\n",
       "      <td>-0.008341</td>\n",
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       "      <td>-0.007273</td>\n",
       "      <td>-0.004733</td>\n",
       "      <td>-0.016409</td>\n",
       "      <td>0.000589</td>\n",
       "      <td>-0.013436</td>\n",
       "      <td>-0.003375</td>\n",
       "      <td>-0.001031</td>\n",
       "      <td>-0.002515</td>\n",
       "      <td>0.000641</td>\n",
       "      <td>-0.006599</td>\n",
       "      <td>-0.003413</td>\n",
       "      <td>0.000296</td>\n",
       "      <td>0.005005</td>\n",
       "      <td>0.002982</td>\n",
       "      <td>-0.002999</td>\n",
       "      <td>-0.009885</td>\n",
       "      <td>0.006631</td>\n",
       "      <td>-0.009635</td>\n",
       "      <td>0.009253</td>\n",
       "      <td>-0.002978</td>\n",
       "      <td>0.000200</td>\n",
       "      <td>-0.008646</td>\n",
       "      <td>0.001253</td>\n",
       "      <td>0.003193</td>\n",
       "      <td>0.010034</td>\n",
       "      <td>0.006923</td>\n",
       "      <td>-0.007371</td>\n",
       "      <td>-0.008663</td>\n",
       "      <td>-0.005403</td>\n",
       "      <td>-0.005219</td>\n",
       "      <td>0.003343</td>\n",
       "      <td>0.000165</td>\n",
       "      <td>-0.012555</td>\n",
       "      <td>-0.001912</td>\n",
       "      <td>-0.006776</td>\n",
       "      <td>0.009576</td>\n",
       "      <td>-0.001182</td>\n",
       "      <td>-0.004070</td>\n",
       "      <td>7.0</td>\n",
       "      <td>63</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3730</th>\n",
       "      <td>-0.013817</td>\n",
       "      <td>0.029486</td>\n",
       "      <td>0.004163</td>\n",
       "      <td>-0.006857</td>\n",
       "      <td>-0.003146</td>\n",
       "      <td>-0.006858</td>\n",
       "      <td>-0.005760</td>\n",
       "      <td>-0.020783</td>\n",
       "      <td>-0.013606</td>\n",
       "      <td>-0.005511</td>\n",
       "      <td>0.004536</td>\n",
       "      <td>0.002366</td>\n",
       "      <td>-0.011819</td>\n",
       "      <td>0.009227</td>\n",
       "      <td>0.000824</td>\n",
       "      <td>-0.009165</td>\n",
       "      <td>0.005680</td>\n",
       "      <td>0.002049</td>\n",
       "      <td>-0.004772</td>\n",
       "      <td>0.009497</td>\n",
       "      <td>-0.001135</td>\n",
       "      <td>0.002838</td>\n",
       "      <td>-0.005431</td>\n",
       "      <td>0.017724</td>\n",
       "      <td>-0.018711</td>\n",
       "      <td>0.004037</td>\n",
       "      <td>-0.002446</td>\n",
       "      <td>0.013329</td>\n",
       "      <td>0.019957</td>\n",
       "      <td>0.002075</td>\n",
       "      <td>-0.008593</td>\n",
       "      <td>-0.031132</td>\n",
       "      <td>0.016551</td>\n",
       "      <td>-0.007283</td>\n",
       "      <td>0.000183</td>\n",
       "      <td>0.008546</td>\n",
       "      <td>0.015197</td>\n",
       "      <td>0.005375</td>\n",
       "      <td>-0.027229</td>\n",
       "      <td>0.001234</td>\n",
       "      <td>0.003968</td>\n",
       "      <td>-0.012269</td>\n",
       "      <td>0.004832</td>\n",
       "      <td>0.030357</td>\n",
       "      <td>0.006682</td>\n",
       "      <td>0.022506</td>\n",
       "      <td>-0.003107</td>\n",
       "      <td>0.004709</td>\n",
       "      <td>0.015330</td>\n",
       "      <td>0.011958</td>\n",
       "      <td>-0.012516</td>\n",
       "      <td>0.010450</td>\n",
       "      <td>0.010154</td>\n",
       "      <td>-0.001952</td>\n",
       "      <td>-0.009371</td>\n",
       "      <td>0.000979</td>\n",
       "      <td>0.001045</td>\n",
       "      <td>-0.018790</td>\n",
       "      <td>0.030410</td>\n",
       "      <td>-0.015791</td>\n",
       "      <td>-0.010844</td>\n",
       "      <td>-0.010366</td>\n",
       "      <td>-0.019603</td>\n",
       "      <td>0.012453</td>\n",
       "      <td>-0.011735</td>\n",
       "      <td>-0.009174</td>\n",
       "      <td>-0.011356</td>\n",
       "      <td>0.002003</td>\n",
       "      <td>0.026720</td>\n",
       "      <td>-0.014379</td>\n",
       "      <td>-0.004154</td>\n",
       "      <td>-0.005030</td>\n",
       "      <td>0.010091</td>\n",
       "      <td>0.004844</td>\n",
       "      <td>-0.016566</td>\n",
       "      <td>-0.018063</td>\n",
       "      <td>0.017815</td>\n",
       "      <td>-0.001962</td>\n",
       "      <td>0.023236</td>\n",
       "      <td>-0.016707</td>\n",
       "      <td>-0.010219</td>\n",
       "      <td>0.018616</td>\n",
       "      <td>0.005775</td>\n",
       "      <td>0.001706</td>\n",
       "      <td>0.003636</td>\n",
       "      <td>-0.013513</td>\n",
       "      <td>-0.006076</td>\n",
       "      <td>-0.015916</td>\n",
       "      <td>-0.015545</td>\n",
       "      <td>-0.043431</td>\n",
       "      <td>-0.019811</td>\n",
       "      <td>0.017508</td>\n",
       "      <td>0.004577</td>\n",
       "      <td>-0.008067</td>\n",
       "      <td>-0.007936</td>\n",
       "      <td>0.005138</td>\n",
       "      <td>-0.023033</td>\n",
       "      <td>0.019174</td>\n",
       "      <td>0.014443</td>\n",
       "      <td>0.004330</td>\n",
       "      <td>-0.024569</td>\n",
       "      <td>0.003846</td>\n",
       "      <td>-0.005940</td>\n",
       "      <td>0.009754</td>\n",
       "      <td>-0.002102</td>\n",
       "      <td>0.009882</td>\n",
       "      <td>0.001693</td>\n",
       "      <td>-0.030379</td>\n",
       "      <td>0.010157</td>\n",
       "      <td>-0.000368</td>\n",
       "      <td>0.007206</td>\n",
       "      <td>-0.006936</td>\n",
       "      <td>-0.026398</td>\n",
       "      <td>-0.010783</td>\n",
       "      <td>-0.000808</td>\n",
       "      <td>-0.008741</td>\n",
       "      <td>-0.003591</td>\n",
       "      <td>0.006397</td>\n",
       "      <td>0.013311</td>\n",
       "      <td>0.020450</td>\n",
       "      <td>0.021508</td>\n",
       "      <td>-0.003182</td>\n",
       "      <td>0.016967</td>\n",
       "      <td>0.004793</td>\n",
       "      <td>0.018619</td>\n",
       "      <td>0.003864</td>\n",
       "      <td>-0.004481</td>\n",
       "      <td>0.007448</td>\n",
       "      <td>-0.010699</td>\n",
       "      <td>-0.003103</td>\n",
       "      <td>0.004254</td>\n",
       "      <td>-0.007405</td>\n",
       "      <td>0.005357</td>\n",
       "      <td>0.009162</td>\n",
       "      <td>-0.010082</td>\n",
       "      <td>0.000335</td>\n",
       "      <td>0.018767</td>\n",
       "      <td>0.010207</td>\n",
       "      <td>0.004382</td>\n",
       "      <td>-0.030507</td>\n",
       "      <td>0.000174</td>\n",
       "      <td>0.020003</td>\n",
       "      <td>0.016618</td>\n",
       "      <td>0.005997</td>\n",
       "      <td>0.013674</td>\n",
       "      <td>0.012354</td>\n",
       "      <td>-0.007659</td>\n",
       "      <td>-0.005620</td>\n",
       "      <td>0.027860</td>\n",
       "      <td>0.009417</td>\n",
       "      <td>0.000160</td>\n",
       "      <td>-0.017519</td>\n",
       "      <td>0.008741</td>\n",
       "      <td>0.004206</td>\n",
       "      <td>0.017736</td>\n",
       "      <td>0.004551</td>\n",
       "      <td>-0.031189</td>\n",
       "      <td>-0.008378</td>\n",
       "      <td>0.013416</td>\n",
       "      <td>0.017877</td>\n",
       "      <td>-0.015795</td>\n",
       "      <td>0.006893</td>\n",
       "      <td>0.002410</td>\n",
       "      <td>-0.008935</td>\n",
       "      <td>0.018810</td>\n",
       "      <td>0.003437</td>\n",
       "      <td>-0.011405</td>\n",
       "      <td>0.002271</td>\n",
       "      <td>-0.011639</td>\n",
       "      <td>-0.003768</td>\n",
       "      <td>0.001463</td>\n",
       "      <td>0.022149</td>\n",
       "      <td>0.007753</td>\n",
       "      <td>0.011312</td>\n",
       "      <td>0.016575</td>\n",
       "      <td>0.001292</td>\n",
       "      <td>-0.004871</td>\n",
       "      <td>0.027889</td>\n",
       "      <td>-0.004440</td>\n",
       "      <td>0.001244</td>\n",
       "      <td>0.030290</td>\n",
       "      <td>0.006598</td>\n",
       "      <td>0.021688</td>\n",
       "      <td>-0.015311</td>\n",
       "      <td>-0.033538</td>\n",
       "      <td>-0.023275</td>\n",
       "      <td>-0.005647</td>\n",
       "      <td>-0.005842</td>\n",
       "      <td>-0.014474</td>\n",
       "      <td>-0.023420</td>\n",
       "      <td>0.012506</td>\n",
       "      <td>-0.001489</td>\n",
       "      <td>-0.013685</td>\n",
       "      <td>0.002451</td>\n",
       "      <td>-0.016600</td>\n",
       "      <td>-0.004520</td>\n",
       "      <td>-0.013680</td>\n",
       "      <td>0.008426</td>\n",
       "      <td>0.015952</td>\n",
       "      <td>0.028872</td>\n",
       "      <td>-0.037229</td>\n",
       "      <td>-0.015976</td>\n",
       "      <td>0.003183</td>\n",
       "      <td>-0.012937</td>\n",
       "      <td>-0.020843</td>\n",
       "      <td>0.008284</td>\n",
       "      <td>-0.005596</td>\n",
       "      <td>-0.019925</td>\n",
       "      <td>-0.006461</td>\n",
       "      <td>-0.002456</td>\n",
       "      <td>-0.004706</td>\n",
       "      <td>0.005286</td>\n",
       "      <td>0.001027</td>\n",
       "      <td>-0.012596</td>\n",
       "      <td>0.010458</td>\n",
       "      <td>0.024066</td>\n",
       "      <td>-0.014056</td>\n",
       "      <td>0.009543</td>\n",
       "      <td>0.015331</td>\n",
       "      <td>0.027695</td>\n",
       "      <td>-0.002671</td>\n",
       "      <td>-0.000830</td>\n",
       "      <td>-0.027700</td>\n",
       "      <td>-0.006220</td>\n",
       "      <td>-0.016267</td>\n",
       "      <td>0.004343</td>\n",
       "      <td>-0.038930</td>\n",
       "      <td>-0.048439</td>\n",
       "      <td>0.002198</td>\n",
       "      <td>0.005094</td>\n",
       "      <td>0.008482</td>\n",
       "      <td>0.026688</td>\n",
       "      <td>-0.000298</td>\n",
       "      <td>-0.012697</td>\n",
       "      <td>-0.057924</td>\n",
       "      <td>-0.002096</td>\n",
       "      <td>-0.006134</td>\n",
       "      <td>-0.006936</td>\n",
       "      <td>-0.004946</td>\n",
       "      <td>-0.036442</td>\n",
       "      <td>-0.008732</td>\n",
       "      <td>-0.029264</td>\n",
       "      <td>0.001365</td>\n",
       "      <td>0.012135</td>\n",
       "      <td>-0.000512</td>\n",
       "      <td>0.025843</td>\n",
       "      <td>0.006282</td>\n",
       "      <td>0.012127</td>\n",
       "      <td>0.005752</td>\n",
       "      <td>0.005255</td>\n",
       "      <td>0.011738</td>\n",
       "      <td>0.008681</td>\n",
       "      <td>0.000073</td>\n",
       "      <td>0.014849</td>\n",
       "      <td>0.014899</td>\n",
       "      <td>-0.004914</td>\n",
       "      <td>-0.013113</td>\n",
       "      <td>-0.001688</td>\n",
       "      <td>0.021950</td>\n",
       "      <td>0.019597</td>\n",
       "      <td>-0.009977</td>\n",
       "      <td>-0.007407</td>\n",
       "      <td>0.015345</td>\n",
       "      <td>0.003677</td>\n",
       "      <td>0.008805</td>\n",
       "      <td>-0.024123</td>\n",
       "      <td>0.021233</td>\n",
       "      <td>-0.005877</td>\n",
       "      <td>0.014373</td>\n",
       "      <td>0.008299</td>\n",
       "      <td>-0.008483</td>\n",
       "      <td>-0.021132</td>\n",
       "      <td>-0.012268</td>\n",
       "      <td>-0.004630</td>\n",
       "      <td>0.018824</td>\n",
       "      <td>0.025683</td>\n",
       "      <td>0.012428</td>\n",
       "      <td>-0.013444</td>\n",
       "      <td>-0.010013</td>\n",
       "      <td>0.014688</td>\n",
       "      <td>-0.015751</td>\n",
       "      <td>-0.010913</td>\n",
       "      <td>0.016157</td>\n",
       "      <td>0.002249</td>\n",
       "      <td>-0.009124</td>\n",
       "      <td>0.020179</td>\n",
       "      <td>-0.012145</td>\n",
       "      <td>0.002175</td>\n",
       "      <td>0.001706</td>\n",
       "      <td>-0.023561</td>\n",
       "      <td>-0.004761</td>\n",
       "      <td>-0.004586</td>\n",
       "      <td>0.002234</td>\n",
       "      <td>-0.001120</td>\n",
       "      <td>0.002910</td>\n",
       "      <td>-0.008645</td>\n",
       "      <td>0.002400</td>\n",
       "      <td>0.004226</td>\n",
       "      <td>-0.021091</td>\n",
       "      <td>0.027466</td>\n",
       "      <td>-0.009177</td>\n",
       "      <td>0.027249</td>\n",
       "      <td>0.013514</td>\n",
       "      <td>0.026456</td>\n",
       "      <td>0.008286</td>\n",
       "      <td>0.003781</td>\n",
       "      <td>-0.004711</td>\n",
       "      <td>0.012006</td>\n",
       "      <td>0.011057</td>\n",
       "      <td>-0.018747</td>\n",
       "      <td>0.020571</td>\n",
       "      <td>-0.000393</td>\n",
       "      <td>-0.003628</td>\n",
       "      <td>-0.016818</td>\n",
       "      <td>0.008840</td>\n",
       "      <td>0.010729</td>\n",
       "      <td>-0.023234</td>\n",
       "      <td>-0.016622</td>\n",
       "      <td>0.011651</td>\n",
       "      <td>0.000845</td>\n",
       "      <td>-0.015170</td>\n",
       "      <td>-0.000039</td>\n",
       "      <td>0.037639</td>\n",
       "      <td>-0.020263</td>\n",
       "      <td>-0.012922</td>\n",
       "      <td>-0.019020</td>\n",
       "      <td>-0.007290</td>\n",
       "      <td>0.023110</td>\n",
       "      <td>-0.002444</td>\n",
       "      <td>0.006725</td>\n",
       "      <td>0.018956</td>\n",
       "      <td>0.017200</td>\n",
       "      <td>0.016808</td>\n",
       "      <td>0.008267</td>\n",
       "      <td>0.003829</td>\n",
       "      <td>0.016535</td>\n",
       "      <td>0.019509</td>\n",
       "      <td>-0.027012</td>\n",
       "      <td>-0.008585</td>\n",
       "      <td>0.012843</td>\n",
       "      <td>0.003686</td>\n",
       "      <td>-0.008765</td>\n",
       "      <td>-0.025487</td>\n",
       "      <td>0.016293</td>\n",
       "      <td>0.000486</td>\n",
       "      <td>-0.002395</td>\n",
       "      <td>-0.019329</td>\n",
       "      <td>0.004896</td>\n",
       "      <td>-0.019846</td>\n",
       "      <td>0.018259</td>\n",
       "      <td>0.018928</td>\n",
       "      <td>0.013720</td>\n",
       "      <td>0.006582</td>\n",
       "      <td>0.000795</td>\n",
       "      <td>0.002681</td>\n",
       "      <td>0.003390</td>\n",
       "      <td>-0.002716</td>\n",
       "      <td>-0.036276</td>\n",
       "      <td>0.005339</td>\n",
       "      <td>0.017486</td>\n",
       "      <td>-0.018151</td>\n",
       "      <td>0.028371</td>\n",
       "      <td>0.011351</td>\n",
       "      <td>0.019997</td>\n",
       "      <td>-0.008388</td>\n",
       "      <td>0.011579</td>\n",
       "      <td>0.009312</td>\n",
       "      <td>-0.012051</td>\n",
       "      <td>-0.012738</td>\n",
       "      <td>-0.024657</td>\n",
       "      <td>0.031917</td>\n",
       "      <td>0.018775</td>\n",
       "      <td>0.023695</td>\n",
       "      <td>-0.010382</td>\n",
       "      <td>0.012623</td>\n",
       "      <td>-0.015960</td>\n",
       "      <td>0.011013</td>\n",
       "      <td>-0.005605</td>\n",
       "      <td>0.029884</td>\n",
       "      <td>0.013076</td>\n",
       "      <td>0.003900</td>\n",
       "      <td>-0.024338</td>\n",
       "      <td>-0.003345</td>\n",
       "      <td>0.010329</td>\n",
       "      <td>-0.015505</td>\n",
       "      <td>0.002316</td>\n",
       "      <td>0.011643</td>\n",
       "      <td>-0.011254</td>\n",
       "      <td>-0.024316</td>\n",
       "      <td>-0.002473</td>\n",
       "      <td>0.035248</td>\n",
       "      <td>0.037451</td>\n",
       "      <td>0.017364</td>\n",
       "      <td>-0.009418</td>\n",
       "      <td>0.008618</td>\n",
       "      <td>-0.005707</td>\n",
       "      <td>-0.003262</td>\n",
       "      <td>-0.010717</td>\n",
       "      <td>-0.014498</td>\n",
       "      <td>-0.008410</td>\n",
       "      <td>-0.007603</td>\n",
       "      <td>-0.002047</td>\n",
       "      <td>0.001500</td>\n",
       "      <td>0.005096</td>\n",
       "      <td>0.005138</td>\n",
       "      <td>-0.002495</td>\n",
       "      <td>-0.004317</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.014649</td>\n",
       "      <td>-0.014603</td>\n",
       "      <td>0.002404</td>\n",
       "      <td>-0.008988</td>\n",
       "      <td>-0.013330</td>\n",
       "      <td>0.020069</td>\n",
       "      <td>0.001229</td>\n",
       "      <td>-0.009486</td>\n",
       "      <td>-0.006222</td>\n",
       "      <td>0.019939</td>\n",
       "      <td>-0.026626</td>\n",
       "      <td>-0.023253</td>\n",
       "      <td>-0.019233</td>\n",
       "      <td>-0.018837</td>\n",
       "      <td>-0.020334</td>\n",
       "      <td>-0.013728</td>\n",
       "      <td>0.013061</td>\n",
       "      <td>0.001492</td>\n",
       "      <td>-0.004557</td>\n",
       "      <td>-0.000197</td>\n",
       "      <td>-0.014610</td>\n",
       "      <td>-0.000706</td>\n",
       "      <td>-0.014485</td>\n",
       "      <td>0.004243</td>\n",
       "      <td>-0.014393</td>\n",
       "      <td>-0.000101</td>\n",
       "      <td>0.003122</td>\n",
       "      <td>-0.018264</td>\n",
       "      <td>0.039440</td>\n",
       "      <td>0.014422</td>\n",
       "      <td>0.032140</td>\n",
       "      <td>0.012190</td>\n",
       "      <td>-0.003571</td>\n",
       "      <td>0.016807</td>\n",
       "      <td>0.019382</td>\n",
       "      <td>0.004898</td>\n",
       "      <td>0.012955</td>\n",
       "      <td>0.000970</td>\n",
       "      <td>-0.007349</td>\n",
       "      <td>-0.002431</td>\n",
       "      <td>-0.030710</td>\n",
       "      <td>0.001747</td>\n",
       "      <td>0.012075</td>\n",
       "      <td>0.000942</td>\n",
       "      <td>0.014193</td>\n",
       "      <td>0.017416</td>\n",
       "      <td>0.001037</td>\n",
       "      <td>-0.024588</td>\n",
       "      <td>0.006512</td>\n",
       "      <td>-0.018061</td>\n",
       "      <td>0.000211</td>\n",
       "      <td>-0.005669</td>\n",
       "      <td>-0.017656</td>\n",
       "      <td>-0.007124</td>\n",
       "      <td>0.005366</td>\n",
       "      <td>-0.004698</td>\n",
       "      <td>0.002554</td>\n",
       "      <td>0.002845</td>\n",
       "      <td>-0.006927</td>\n",
       "      <td>0.005540</td>\n",
       "      <td>0.007238</td>\n",
       "      <td>-0.009931</td>\n",
       "      <td>0.004671</td>\n",
       "      <td>-0.018042</td>\n",
       "      <td>0.003460</td>\n",
       "      <td>-0.028388</td>\n",
       "      <td>-0.019505</td>\n",
       "      <td>0.031830</td>\n",
       "      <td>0.023013</td>\n",
       "      <td>0.027218</td>\n",
       "      <td>-0.009189</td>\n",
       "      <td>0.010745</td>\n",
       "      <td>0.020323</td>\n",
       "      <td>0.010224</td>\n",
       "      <td>0.014833</td>\n",
       "      <td>0.009064</td>\n",
       "      <td>0.015039</td>\n",
       "      <td>0.016383</td>\n",
       "      <td>-0.016678</td>\n",
       "      <td>-0.013427</td>\n",
       "      <td>-0.009442</td>\n",
       "      <td>0.019582</td>\n",
       "      <td>-0.004413</td>\n",
       "      <td>0.008305</td>\n",
       "      <td>0.010303</td>\n",
       "      <td>-0.011631</td>\n",
       "      <td>-0.006837</td>\n",
       "      <td>-0.006635</td>\n",
       "      <td>-0.027491</td>\n",
       "      <td>0.000509</td>\n",
       "      <td>0.020468</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.015112</td>\n",
       "      <td>-0.008030</td>\n",
       "      <td>0.004720</td>\n",
       "      <td>-0.007456</td>\n",
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       "      <td>-0.019500</td>\n",
       "      <td>-0.028238</td>\n",
       "      <td>-0.010752</td>\n",
       "      <td>-0.014035</td>\n",
       "      <td>-0.000292</td>\n",
       "      <td>0.014580</td>\n",
       "      <td>-0.004342</td>\n",
       "      <td>0.007126</td>\n",
       "      <td>0.006651</td>\n",
       "      <td>0.017305</td>\n",
       "      <td>0.008416</td>\n",
       "      <td>0.000543</td>\n",
       "      <td>-0.005400</td>\n",
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       "      <td>-0.029415</td>\n",
       "      <td>-0.004122</td>\n",
       "      <td>-0.012762</td>\n",
       "      <td>-0.026895</td>\n",
       "      <td>-0.020959</td>\n",
       "      <td>0.015965</td>\n",
       "      <td>0.010703</td>\n",
       "      <td>-0.014607</td>\n",
       "      <td>-0.026883</td>\n",
       "      <td>0.012530</td>\n",
       "      <td>-0.000562</td>\n",
       "      <td>-0.006707</td>\n",
       "      <td>-0.038329</td>\n",
       "      <td>0.026691</td>\n",
       "      <td>-0.011008</td>\n",
       "      <td>0.005045</td>\n",
       "      <td>-0.015814</td>\n",
       "      <td>-0.004127</td>\n",
       "      <td>0.001770</td>\n",
       "      <td>-0.002015</td>\n",
       "      <td>-0.031149</td>\n",
       "      <td>-0.006165</td>\n",
       "      <td>-0.015228</td>\n",
       "      <td>-0.009631</td>\n",
       "      <td>0.013656</td>\n",
       "      <td>-0.024843</td>\n",
       "      <td>0.006111</td>\n",
       "      <td>-0.014701</td>\n",
       "      <td>-0.005864</td>\n",
       "      <td>-0.002459</td>\n",
       "      <td>0.015309</td>\n",
       "      <td>-0.005177</td>\n",
       "      <td>0.004746</td>\n",
       "      <td>0.007240</td>\n",
       "      <td>0.011619</td>\n",
       "      <td>0.008346</td>\n",
       "      <td>0.023003</td>\n",
       "      <td>0.029756</td>\n",
       "      <td>-0.028776</td>\n",
       "      <td>-0.005504</td>\n",
       "      <td>0.023072</td>\n",
       "      <td>-0.011226</td>\n",
       "      <td>0.020669</td>\n",
       "      <td>-0.010567</td>\n",
       "      <td>-0.002758</td>\n",
       "      <td>-0.010072</td>\n",
       "      <td>-0.030236</td>\n",
       "      <td>-0.011779</td>\n",
       "      <td>-0.026493</td>\n",
       "      <td>-0.007765</td>\n",
       "      <td>-0.000602</td>\n",
       "      <td>-0.004721</td>\n",
       "      <td>-0.017744</td>\n",
       "      <td>0.001321</td>\n",
       "      <td>0.009532</td>\n",
       "      <td>-0.000188</td>\n",
       "      <td>-0.015428</td>\n",
       "      <td>-0.036221</td>\n",
       "      <td>0.047065</td>\n",
       "      <td>-0.030654</td>\n",
       "      <td>-0.002206</td>\n",
       "      <td>-0.030116</td>\n",
       "      <td>-0.025677</td>\n",
       "      <td>0.011747</td>\n",
       "      <td>0.001526</td>\n",
       "      <td>0.021477</td>\n",
       "      <td>0.001557</td>\n",
       "      <td>-0.040226</td>\n",
       "      <td>-0.019893</td>\n",
       "      <td>-0.002987</td>\n",
       "      <td>-0.009864</td>\n",
       "      <td>-0.154125</td>\n",
       "      <td>-0.011911</td>\n",
       "      <td>-0.006457</td>\n",
       "      <td>0.005643</td>\n",
       "      <td>-0.018789</td>\n",
       "      <td>-0.013782</td>\n",
       "      <td>0.008661</td>\n",
       "      <td>-0.009733</td>\n",
       "      <td>0.013039</td>\n",
       "      <td>-0.023416</td>\n",
       "      <td>0.002759</td>\n",
       "      <td>0.009994</td>\n",
       "      <td>-0.010633</td>\n",
       "      <td>0.022738</td>\n",
       "      <td>0.014133</td>\n",
       "      <td>0.013247</td>\n",
       "      <td>0.002191</td>\n",
       "      <td>0.013585</td>\n",
       "      <td>0.000447</td>\n",
       "      <td>0.002308</td>\n",
       "      <td>-0.009974</td>\n",
       "      <td>-0.017590</td>\n",
       "      <td>-0.011969</td>\n",
       "      <td>-0.001343</td>\n",
       "      <td>-0.006366</td>\n",
       "      <td>-0.022283</td>\n",
       "      <td>0.022161</td>\n",
       "      <td>0.010663</td>\n",
       "      <td>0.024728</td>\n",
       "      <td>0.020325</td>\n",
       "      <td>0.020496</td>\n",
       "      <td>-0.017363</td>\n",
       "      <td>0.045114</td>\n",
       "      <td>-0.003959</td>\n",
       "      <td>0.004207</td>\n",
       "      <td>0.000816</td>\n",
       "      <td>-0.022021</td>\n",
       "      <td>-0.000884</td>\n",
       "      <td>0.026293</td>\n",
       "      <td>0.000186</td>\n",
       "      <td>-0.002186</td>\n",
       "      <td>-0.001836</td>\n",
       "      <td>0.018321</td>\n",
       "      <td>-0.008159</td>\n",
       "      <td>0.005986</td>\n",
       "      <td>-0.010864</td>\n",
       "      <td>-0.000798</td>\n",
       "      <td>-0.027278</td>\n",
       "      <td>0.018430</td>\n",
       "      <td>0.005589</td>\n",
       "      <td>0.026282</td>\n",
       "      <td>-0.029662</td>\n",
       "      <td>-0.001365</td>\n",
       "      <td>-0.009846</td>\n",
       "      <td>0.015646</td>\n",
       "      <td>-0.024848</td>\n",
       "      <td>-0.014368</td>\n",
       "      <td>-0.019180</td>\n",
       "      <td>0.006436</td>\n",
       "      <td>0.022819</td>\n",
       "      <td>0.034319</td>\n",
       "      <td>-0.007180</td>\n",
       "      <td>0.006381</td>\n",
       "      <td>-0.039981</td>\n",
       "      <td>0.000517</td>\n",
       "      <td>0.015241</td>\n",
       "      <td>0.016596</td>\n",
       "      <td>0.018855</td>\n",
       "      <td>0.020741</td>\n",
       "      <td>0.007227</td>\n",
       "      <td>0.039614</td>\n",
       "      <td>0.023792</td>\n",
       "      <td>-0.009778</td>\n",
       "      <td>-0.011070</td>\n",
       "      <td>0.001604</td>\n",
       "      <td>0.005568</td>\n",
       "      <td>-0.013704</td>\n",
       "      <td>-0.008019</td>\n",
       "      <td>0.007901</td>\n",
       "      <td>0.013811</td>\n",
       "      <td>0.010576</td>\n",
       "      <td>-0.013372</td>\n",
       "      <td>0.004485</td>\n",
       "      <td>0.000714</td>\n",
       "      <td>-0.002843</td>\n",
       "      <td>-0.006731</td>\n",
       "      <td>-0.007695</td>\n",
       "      <td>-0.000244</td>\n",
       "      <td>0.002664</td>\n",
       "      <td>-0.014306</td>\n",
       "      <td>-0.025652</td>\n",
       "      <td>-0.010265</td>\n",
       "      <td>0.018915</td>\n",
       "      <td>0.008392</td>\n",
       "      <td>-0.002735</td>\n",
       "      <td>0.009625</td>\n",
       "      <td>-0.000045</td>\n",
       "      <td>0.019280</td>\n",
       "      <td>-0.011543</td>\n",
       "      <td>-0.003635</td>\n",
       "      <td>-0.009208</td>\n",
       "      <td>-0.002398</td>\n",
       "      <td>0.018267</td>\n",
       "      <td>-0.018103</td>\n",
       "      <td>-0.010019</td>\n",
       "      <td>-0.005060</td>\n",
       "      <td>-0.020002</td>\n",
       "      <td>-0.008267</td>\n",
       "      <td>-0.024416</td>\n",
       "      <td>-0.000172</td>\n",
       "      <td>0.005998</td>\n",
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       "      <td>-0.019445</td>\n",
       "      <td>0.013879</td>\n",
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       "      <td>0.005096</td>\n",
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       "      <td>0.016225</td>\n",
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       "      <td>0.008847</td>\n",
       "      <td>-0.004736</td>\n",
       "      <td>-0.038601</td>\n",
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       "      <td>-0.003306</td>\n",
       "      <td>-0.010698</td>\n",
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       "      <td>0.002207</td>\n",
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       "      <td>0.001123</td>\n",
       "      <td>-0.020889</td>\n",
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       "      <td>0.020677</td>\n",
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       "      <td>-0.028103</td>\n",
       "      <td>0.000033</td>\n",
       "      <td>0.022006</td>\n",
       "      <td>-0.034320</td>\n",
       "      <td>0.023572</td>\n",
       "      <td>0.026788</td>\n",
       "      <td>0.012450</td>\n",
       "      <td>-0.017769</td>\n",
       "      <td>0.006946</td>\n",
       "      <td>0.013706</td>\n",
       "      <td>-0.001218</td>\n",
       "      <td>-0.015515</td>\n",
       "      <td>0.020259</td>\n",
       "      <td>0.009028</td>\n",
       "      <td>0.010207</td>\n",
       "      <td>-0.021500</td>\n",
       "      <td>0.010486</td>\n",
       "      <td>-0.000034</td>\n",
       "      <td>0.014982</td>\n",
       "      <td>-0.002508</td>\n",
       "      <td>-0.006881</td>\n",
       "      <td>-0.003400</td>\n",
       "      <td>0.006935</td>\n",
       "      <td>-0.001289</td>\n",
       "      <td>0.010740</td>\n",
       "      <td>0.001525</td>\n",
       "      <td>-0.002616</td>\n",
       "      <td>0.002032</td>\n",
       "      <td>0.006760</td>\n",
       "      <td>-0.002962</td>\n",
       "      <td>0.013703</td>\n",
       "      <td>-0.014754</td>\n",
       "      <td>0.021360</td>\n",
       "      <td>0.013718</td>\n",
       "      <td>0.039999</td>\n",
       "      <td>0.004008</td>\n",
       "      <td>0.005189</td>\n",
       "      <td>0.029875</td>\n",
       "      <td>0.016394</td>\n",
       "      <td>0.015664</td>\n",
       "      <td>0.024258</td>\n",
       "      <td>-0.004852</td>\n",
       "      <td>0.003751</td>\n",
       "      <td>-0.009283</td>\n",
       "      <td>-0.021068</td>\n",
       "      <td>-0.039508</td>\n",
       "      <td>0.014124</td>\n",
       "      <td>0.014023</td>\n",
       "      <td>-0.003695</td>\n",
       "      <td>0.019858</td>\n",
       "      <td>-0.008319</td>\n",
       "      <td>0.004834</td>\n",
       "      <td>0.012843</td>\n",
       "      <td>-0.003913</td>\n",
       "      <td>0.023786</td>\n",
       "      <td>0.010913</td>\n",
       "      <td>0.020706</td>\n",
       "      <td>-0.025974</td>\n",
       "      <td>0.022801</td>\n",
       "      <td>0.001787</td>\n",
       "      <td>0.002249</td>\n",
       "      <td>-0.012384</td>\n",
       "      <td>-0.005151</td>\n",
       "      <td>-0.017593</td>\n",
       "      <td>-0.029052</td>\n",
       "      <td>-0.027120</td>\n",
       "      <td>-0.015469</td>\n",
       "      <td>-0.007616</td>\n",
       "      <td>0.005637</td>\n",
       "      <td>0.002936</td>\n",
       "      <td>0.006068</td>\n",
       "      <td>0.009686</td>\n",
       "      <td>-0.003360</td>\n",
       "      <td>-0.004049</td>\n",
       "      <td>0.007157</td>\n",
       "      <td>-0.006606</td>\n",
       "      <td>-0.009528</td>\n",
       "      <td>0.005363</td>\n",
       "      <td>-0.009573</td>\n",
       "      <td>-0.012623</td>\n",
       "      <td>0.015875</td>\n",
       "      <td>-0.008481</td>\n",
       "      <td>0.002714</td>\n",
       "      <td>0.007982</td>\n",
       "      <td>0.015813</td>\n",
       "      <td>0.003552</td>\n",
       "      <td>0.024348</td>\n",
       "      <td>0.000703</td>\n",
       "      <td>-0.007246</td>\n",
       "      <td>0.005146</td>\n",
       "      <td>-0.013379</td>\n",
       "      <td>0.015008</td>\n",
       "      <td>0.000395</td>\n",
       "      <td>-0.032967</td>\n",
       "      <td>-0.017383</td>\n",
       "      <td>-0.016805</td>\n",
       "      <td>0.029942</td>\n",
       "      <td>-0.025934</td>\n",
       "      <td>-0.007565</td>\n",
       "      <td>7.0</td>\n",
       "      <td>63</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3731</th>\n",
       "      <td>-0.007250</td>\n",
       "      <td>0.010681</td>\n",
       "      <td>0.001937</td>\n",
       "      <td>0.001830</td>\n",
       "      <td>-0.000256</td>\n",
       "      <td>0.003161</td>\n",
       "      <td>-0.014018</td>\n",
       "      <td>-0.017502</td>\n",
       "      <td>-0.000072</td>\n",
       "      <td>-0.000415</td>\n",
       "      <td>0.002674</td>\n",
       "      <td>-0.004436</td>\n",
       "      <td>-0.001075</td>\n",
       "      <td>0.008390</td>\n",
       "      <td>0.000579</td>\n",
       "      <td>0.000157</td>\n",
       "      <td>0.007658</td>\n",
       "      <td>-0.003908</td>\n",
       "      <td>-0.004524</td>\n",
       "      <td>0.007933</td>\n",
       "      <td>0.001242</td>\n",
       "      <td>0.005038</td>\n",
       "      <td>-0.006273</td>\n",
       "      <td>0.007947</td>\n",
       "      <td>-0.004193</td>\n",
       "      <td>-0.001508</td>\n",
       "      <td>0.004787</td>\n",
       "      <td>0.006453</td>\n",
       "      <td>0.010137</td>\n",
       "      <td>0.002791</td>\n",
       "      <td>-0.008499</td>\n",
       "      <td>-0.014031</td>\n",
       "      <td>0.011966</td>\n",
       "      <td>-0.005330</td>\n",
       "      <td>0.001109</td>\n",
       "      <td>0.005351</td>\n",
       "      <td>0.002600</td>\n",
       "      <td>0.002456</td>\n",
       "      <td>-0.007334</td>\n",
       "      <td>-0.000589</td>\n",
       "      <td>-0.001588</td>\n",
       "      <td>-0.007897</td>\n",
       "      <td>-0.003211</td>\n",
       "      <td>0.009203</td>\n",
       "      <td>0.009056</td>\n",
       "      <td>0.010293</td>\n",
       "      <td>-0.008282</td>\n",
       "      <td>0.003216</td>\n",
       "      <td>0.003554</td>\n",
       "      <td>0.004690</td>\n",
       "      <td>-0.007954</td>\n",
       "      <td>0.012563</td>\n",
       "      <td>-0.000145</td>\n",
       "      <td>-0.003719</td>\n",
       "      <td>-0.004974</td>\n",
       "      <td>-0.002530</td>\n",
       "      <td>-0.003820</td>\n",
       "      <td>-0.006691</td>\n",
       "      <td>0.005638</td>\n",
       "      <td>-0.015904</td>\n",
       "      <td>-0.003484</td>\n",
       "      <td>-0.000806</td>\n",
       "      <td>-0.010431</td>\n",
       "      <td>0.007221</td>\n",
       "      <td>-0.011856</td>\n",
       "      <td>0.000213</td>\n",
       "      <td>-0.000926</td>\n",
       "      <td>0.005853</td>\n",
       "      <td>0.011368</td>\n",
       "      <td>-0.005753</td>\n",
       "      <td>-0.006626</td>\n",
       "      <td>0.002051</td>\n",
       "      <td>0.006200</td>\n",
       "      <td>-0.000874</td>\n",
       "      <td>-0.006153</td>\n",
       "      <td>-0.009126</td>\n",
       "      <td>0.010836</td>\n",
       "      <td>-0.004327</td>\n",
       "      <td>0.007637</td>\n",
       "      <td>-0.005355</td>\n",
       "      <td>-0.003018</td>\n",
       "      <td>0.012580</td>\n",
       "      <td>0.006697</td>\n",
       "      <td>-0.002883</td>\n",
       "      <td>0.002679</td>\n",
       "      <td>-0.007311</td>\n",
       "      <td>-0.010468</td>\n",
       "      <td>-0.006407</td>\n",
       "      <td>-0.007886</td>\n",
       "      <td>-0.020670</td>\n",
       "      <td>-0.012947</td>\n",
       "      <td>0.011579</td>\n",
       "      <td>0.002128</td>\n",
       "      <td>-0.003013</td>\n",
       "      <td>-0.000399</td>\n",
       "      <td>-0.001320</td>\n",
       "      <td>-0.008404</td>\n",
       "      <td>0.005015</td>\n",
       "      <td>0.007666</td>\n",
       "      <td>-0.000590</td>\n",
       "      <td>-0.014397</td>\n",
       "      <td>0.005685</td>\n",
       "      <td>0.003029</td>\n",
       "      <td>-0.000131</td>\n",
       "      <td>-0.000830</td>\n",
       "      <td>0.002798</td>\n",
       "      <td>-0.000288</td>\n",
       "      <td>-0.018083</td>\n",
       "      <td>-0.000779</td>\n",
       "      <td>-0.002497</td>\n",
       "      <td>0.001682</td>\n",
       "      <td>0.004520</td>\n",
       "      <td>-0.012443</td>\n",
       "      <td>-0.004066</td>\n",
       "      <td>-0.008998</td>\n",
       "      <td>-0.002739</td>\n",
       "      <td>0.000396</td>\n",
       "      <td>0.005075</td>\n",
       "      <td>0.004880</td>\n",
       "      <td>0.007304</td>\n",
       "      <td>0.011346</td>\n",
       "      <td>-0.003428</td>\n",
       "      <td>0.004378</td>\n",
       "      <td>0.002899</td>\n",
       "      <td>0.007395</td>\n",
       "      <td>0.001198</td>\n",
       "      <td>-0.005339</td>\n",
       "      <td>-0.000887</td>\n",
       "      <td>-0.006405</td>\n",
       "      <td>-0.000234</td>\n",
       "      <td>0.000939</td>\n",
       "      <td>-0.004984</td>\n",
       "      <td>0.009300</td>\n",
       "      <td>0.006018</td>\n",
       "      <td>-0.012792</td>\n",
       "      <td>0.000905</td>\n",
       "      <td>0.003390</td>\n",
       "      <td>0.001436</td>\n",
       "      <td>0.000531</td>\n",
       "      <td>-0.013102</td>\n",
       "      <td>-0.004529</td>\n",
       "      <td>0.012801</td>\n",
       "      <td>0.009320</td>\n",
       "      <td>0.002086</td>\n",
       "      <td>0.000250</td>\n",
       "      <td>0.005904</td>\n",
       "      <td>-0.001679</td>\n",
       "      <td>0.003186</td>\n",
       "      <td>0.017235</td>\n",
       "      <td>0.011951</td>\n",
       "      <td>0.007042</td>\n",
       "      <td>-0.011712</td>\n",
       "      <td>-0.001991</td>\n",
       "      <td>0.005952</td>\n",
       "      <td>0.009968</td>\n",
       "      <td>-0.004089</td>\n",
       "      <td>-0.010154</td>\n",
       "      <td>-0.006181</td>\n",
       "      <td>0.009170</td>\n",
       "      <td>0.004156</td>\n",
       "      <td>-0.012418</td>\n",
       "      <td>0.006307</td>\n",
       "      <td>-0.001439</td>\n",
       "      <td>-0.008441</td>\n",
       "      <td>0.005196</td>\n",
       "      <td>0.003037</td>\n",
       "      <td>-0.000832</td>\n",
       "      <td>-0.002481</td>\n",
       "      <td>-0.008815</td>\n",
       "      <td>0.001964</td>\n",
       "      <td>-0.001764</td>\n",
       "      <td>0.007164</td>\n",
       "      <td>0.005435</td>\n",
       "      <td>0.009361</td>\n",
       "      <td>0.002293</td>\n",
       "      <td>-0.006171</td>\n",
       "      <td>-0.000127</td>\n",
       "      <td>0.013808</td>\n",
       "      <td>-0.006503</td>\n",
       "      <td>-0.001582</td>\n",
       "      <td>0.014487</td>\n",
       "      <td>0.002667</td>\n",
       "      <td>0.008659</td>\n",
       "      <td>-0.010944</td>\n",
       "      <td>-0.012319</td>\n",
       "      <td>-0.010742</td>\n",
       "      <td>-0.003507</td>\n",
       "      <td>-0.008380</td>\n",
       "      <td>-0.011294</td>\n",
       "      <td>-0.009130</td>\n",
       "      <td>0.008082</td>\n",
       "      <td>0.004172</td>\n",
       "      <td>-0.011418</td>\n",
       "      <td>0.003180</td>\n",
       "      <td>-0.008517</td>\n",
       "      <td>0.005515</td>\n",
       "      <td>-0.004291</td>\n",
       "      <td>-0.000111</td>\n",
       "      <td>0.008113</td>\n",
       "      <td>0.020709</td>\n",
       "      <td>-0.018188</td>\n",
       "      <td>-0.009293</td>\n",
       "      <td>0.001329</td>\n",
       "      <td>-0.005942</td>\n",
       "      <td>-0.009831</td>\n",
       "      <td>0.003341</td>\n",
       "      <td>-0.005842</td>\n",
       "      <td>-0.008502</td>\n",
       "      <td>0.004439</td>\n",
       "      <td>-0.002149</td>\n",
       "      <td>-0.005633</td>\n",
       "      <td>0.008586</td>\n",
       "      <td>0.006586</td>\n",
       "      <td>-0.005536</td>\n",
       "      <td>0.002291</td>\n",
       "      <td>0.007925</td>\n",
       "      <td>-0.012913</td>\n",
       "      <td>0.007025</td>\n",
       "      <td>0.010065</td>\n",
       "      <td>0.010313</td>\n",
       "      <td>0.001583</td>\n",
       "      <td>0.006456</td>\n",
       "      <td>-0.011551</td>\n",
       "      <td>0.003760</td>\n",
       "      <td>-0.004879</td>\n",
       "      <td>0.002874</td>\n",
       "      <td>-0.017122</td>\n",
       "      <td>-0.018418</td>\n",
       "      <td>-0.003059</td>\n",
       "      <td>-0.000787</td>\n",
       "      <td>-0.000084</td>\n",
       "      <td>0.008450</td>\n",
       "      <td>-0.003417</td>\n",
       "      <td>-0.000330</td>\n",
       "      <td>0.001458</td>\n",
       "      <td>-0.006649</td>\n",
       "      <td>-0.002847</td>\n",
       "      <td>0.005471</td>\n",
       "      <td>-0.002508</td>\n",
       "      <td>-0.021043</td>\n",
       "      <td>-0.003242</td>\n",
       "      <td>-0.010175</td>\n",
       "      <td>-0.005861</td>\n",
       "      <td>0.005688</td>\n",
       "      <td>-0.000224</td>\n",
       "      <td>0.005582</td>\n",
       "      <td>-0.006129</td>\n",
       "      <td>0.005690</td>\n",
       "      <td>0.000106</td>\n",
       "      <td>0.000284</td>\n",
       "      <td>-0.000398</td>\n",
       "      <td>-0.001743</td>\n",
       "      <td>-0.001788</td>\n",
       "      <td>0.002669</td>\n",
       "      <td>0.003655</td>\n",
       "      <td>-0.006038</td>\n",
       "      <td>-0.006654</td>\n",
       "      <td>-0.002928</td>\n",
       "      <td>0.010203</td>\n",
       "      <td>0.006122</td>\n",
       "      <td>-0.003904</td>\n",
       "      <td>-0.009323</td>\n",
       "      <td>0.001753</td>\n",
       "      <td>0.003875</td>\n",
       "      <td>0.007474</td>\n",
       "      <td>-0.007187</td>\n",
       "      <td>0.012889</td>\n",
       "      <td>-0.004892</td>\n",
       "      <td>0.007988</td>\n",
       "      <td>0.006130</td>\n",
       "      <td>-0.004237</td>\n",
       "      <td>-0.015491</td>\n",
       "      <td>-0.002985</td>\n",
       "      <td>-0.002114</td>\n",
       "      <td>0.017150</td>\n",
       "      <td>0.009957</td>\n",
       "      <td>0.005840</td>\n",
       "      <td>-0.008370</td>\n",
       "      <td>-0.010232</td>\n",
       "      <td>0.003640</td>\n",
       "      <td>-0.000778</td>\n",
       "      <td>-0.005113</td>\n",
       "      <td>0.011798</td>\n",
       "      <td>-0.000847</td>\n",
       "      <td>-0.006984</td>\n",
       "      <td>0.004389</td>\n",
       "      <td>-0.009947</td>\n",
       "      <td>0.002091</td>\n",
       "      <td>0.002128</td>\n",
       "      <td>-0.008301</td>\n",
       "      <td>-0.003548</td>\n",
       "      <td>-0.002596</td>\n",
       "      <td>-0.001915</td>\n",
       "      <td>0.002802</td>\n",
       "      <td>0.005804</td>\n",
       "      <td>-0.005198</td>\n",
       "      <td>-0.000159</td>\n",
       "      <td>0.004290</td>\n",
       "      <td>-0.005258</td>\n",
       "      <td>0.008769</td>\n",
       "      <td>-0.003895</td>\n",
       "      <td>0.009030</td>\n",
       "      <td>0.004675</td>\n",
       "      <td>0.010884</td>\n",
       "      <td>0.011658</td>\n",
       "      <td>-0.000005</td>\n",
       "      <td>0.001752</td>\n",
       "      <td>0.003290</td>\n",
       "      <td>0.004382</td>\n",
       "      <td>-0.006575</td>\n",
       "      <td>0.011819</td>\n",
       "      <td>-0.004668</td>\n",
       "      <td>0.008086</td>\n",
       "      <td>-0.011359</td>\n",
       "      <td>0.005302</td>\n",
       "      <td>0.005912</td>\n",
       "      <td>-0.014415</td>\n",
       "      <td>-0.007956</td>\n",
       "      <td>0.013822</td>\n",
       "      <td>-0.006185</td>\n",
       "      <td>0.000902</td>\n",
       "      <td>0.003127</td>\n",
       "      <td>0.013268</td>\n",
       "      <td>-0.019803</td>\n",
       "      <td>-0.007359</td>\n",
       "      <td>-0.011544</td>\n",
       "      <td>-0.000352</td>\n",
       "      <td>0.016176</td>\n",
       "      <td>-0.002981</td>\n",
       "      <td>0.002157</td>\n",
       "      <td>0.010342</td>\n",
       "      <td>0.007120</td>\n",
       "      <td>0.017326</td>\n",
       "      <td>0.007786</td>\n",
       "      <td>0.002741</td>\n",
       "      <td>0.009261</td>\n",
       "      <td>0.002631</td>\n",
       "      <td>-0.013040</td>\n",
       "      <td>-0.001853</td>\n",
       "      <td>0.002749</td>\n",
       "      <td>-0.004039</td>\n",
       "      <td>-0.007352</td>\n",
       "      <td>-0.010777</td>\n",
       "      <td>0.005542</td>\n",
       "      <td>0.004292</td>\n",
       "      <td>-0.002150</td>\n",
       "      <td>-0.003898</td>\n",
       "      <td>-0.005910</td>\n",
       "      <td>-0.007625</td>\n",
       "      <td>0.004452</td>\n",
       "      <td>0.010729</td>\n",
       "      <td>0.004877</td>\n",
       "      <td>0.002951</td>\n",
       "      <td>-0.001958</td>\n",
       "      <td>0.006977</td>\n",
       "      <td>-0.000784</td>\n",
       "      <td>0.006826</td>\n",
       "      <td>-0.015553</td>\n",
       "      <td>0.008585</td>\n",
       "      <td>0.006707</td>\n",
       "      <td>-0.008517</td>\n",
       "      <td>0.015776</td>\n",
       "      <td>0.004063</td>\n",
       "      <td>0.007129</td>\n",
       "      <td>-0.011187</td>\n",
       "      <td>0.003384</td>\n",
       "      <td>-0.001758</td>\n",
       "      <td>0.003525</td>\n",
       "      <td>-0.003497</td>\n",
       "      <td>-0.004741</td>\n",
       "      <td>0.008018</td>\n",
       "      <td>0.011475</td>\n",
       "      <td>0.016289</td>\n",
       "      <td>-0.007971</td>\n",
       "      <td>0.006130</td>\n",
       "      <td>-0.006455</td>\n",
       "      <td>0.006294</td>\n",
       "      <td>-0.002760</td>\n",
       "      <td>0.016162</td>\n",
       "      <td>0.010559</td>\n",
       "      <td>-0.001604</td>\n",
       "      <td>-0.017525</td>\n",
       "      <td>0.001670</td>\n",
       "      <td>0.006313</td>\n",
       "      <td>0.000494</td>\n",
       "      <td>-0.001435</td>\n",
       "      <td>0.007972</td>\n",
       "      <td>-0.003608</td>\n",
       "      <td>-0.013014</td>\n",
       "      <td>0.007858</td>\n",
       "      <td>0.009759</td>\n",
       "      <td>0.023070</td>\n",
       "      <td>0.008099</td>\n",
       "      <td>-0.002389</td>\n",
       "      <td>-0.000982</td>\n",
       "      <td>0.004796</td>\n",
       "      <td>-0.005873</td>\n",
       "      <td>-0.005400</td>\n",
       "      <td>-0.010391</td>\n",
       "      <td>-0.009759</td>\n",
       "      <td>0.003046</td>\n",
       "      <td>-0.000014</td>\n",
       "      <td>0.005470</td>\n",
       "      <td>-0.000112</td>\n",
       "      <td>-0.002741</td>\n",
       "      <td>-0.003076</td>\n",
       "      <td>-0.005538</td>\n",
       "      <td>0.003649</td>\n",
       "      <td>0.008660</td>\n",
       "      <td>-0.006005</td>\n",
       "      <td>-0.003371</td>\n",
       "      <td>-0.006139</td>\n",
       "      <td>-0.001488</td>\n",
       "      <td>0.005504</td>\n",
       "      <td>-0.003258</td>\n",
       "      <td>0.000304</td>\n",
       "      <td>-0.004785</td>\n",
       "      <td>0.007382</td>\n",
       "      <td>-0.011659</td>\n",
       "      <td>-0.014056</td>\n",
       "      <td>-0.005912</td>\n",
       "      <td>-0.005795</td>\n",
       "      <td>-0.004425</td>\n",
       "      <td>-0.008319</td>\n",
       "      <td>0.003497</td>\n",
       "      <td>0.003116</td>\n",
       "      <td>-0.005650</td>\n",
       "      <td>-0.006859</td>\n",
       "      <td>-0.004408</td>\n",
       "      <td>-0.004246</td>\n",
       "      <td>-0.006945</td>\n",
       "      <td>-0.001318</td>\n",
       "      <td>-0.007266</td>\n",
       "      <td>0.001768</td>\n",
       "      <td>0.009522</td>\n",
       "      <td>-0.006623</td>\n",
       "      <td>0.018357</td>\n",
       "      <td>0.004470</td>\n",
       "      <td>0.014693</td>\n",
       "      <td>0.001414</td>\n",
       "      <td>-0.003070</td>\n",
       "      <td>0.007550</td>\n",
       "      <td>0.013773</td>\n",
       "      <td>0.004944</td>\n",
       "      <td>0.005370</td>\n",
       "      <td>0.002428</td>\n",
       "      <td>-0.001078</td>\n",
       "      <td>-0.002055</td>\n",
       "      <td>-0.011071</td>\n",
       "      <td>0.001914</td>\n",
       "      <td>0.001566</td>\n",
       "      <td>0.003519</td>\n",
       "      <td>0.007066</td>\n",
       "      <td>0.007528</td>\n",
       "      <td>0.000634</td>\n",
       "      <td>-0.013057</td>\n",
       "      <td>0.006801</td>\n",
       "      <td>-0.007150</td>\n",
       "      <td>-0.001329</td>\n",
       "      <td>0.005509</td>\n",
       "      <td>-0.006638</td>\n",
       "      <td>-0.008966</td>\n",
       "      <td>0.001817</td>\n",
       "      <td>-0.000446</td>\n",
       "      <td>0.002303</td>\n",
       "      <td>0.005942</td>\n",
       "      <td>-0.007323</td>\n",
       "      <td>-0.002063</td>\n",
       "      <td>0.001885</td>\n",
       "      <td>-0.004651</td>\n",
       "      <td>0.003229</td>\n",
       "      <td>-0.012486</td>\n",
       "      <td>0.006853</td>\n",
       "      <td>-0.004331</td>\n",
       "      <td>-0.007927</td>\n",
       "      <td>0.014663</td>\n",
       "      <td>0.014519</td>\n",
       "      <td>0.005284</td>\n",
       "      <td>0.001951</td>\n",
       "      <td>0.005234</td>\n",
       "      <td>0.014066</td>\n",
       "      <td>-0.001348</td>\n",
       "      <td>0.006465</td>\n",
       "      <td>0.008489</td>\n",
       "      <td>0.010875</td>\n",
       "      <td>0.000297</td>\n",
       "      <td>-0.007541</td>\n",
       "      <td>-0.006323</td>\n",
       "      <td>0.004360</td>\n",
       "      <td>0.010662</td>\n",
       "      <td>-0.002240</td>\n",
       "      <td>0.007829</td>\n",
       "      <td>0.002328</td>\n",
       "      <td>-0.005769</td>\n",
       "      <td>0.001362</td>\n",
       "      <td>-0.004073</td>\n",
       "      <td>-0.014683</td>\n",
       "      <td>-0.001214</td>\n",
       "      <td>0.011927</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.001589</td>\n",
       "      <td>0.000218</td>\n",
       "      <td>-0.001899</td>\n",
       "      <td>-0.001992</td>\n",
       "      <td>0.002621</td>\n",
       "      <td>0.001530</td>\n",
       "      <td>0.002387</td>\n",
       "      <td>-0.008391</td>\n",
       "      <td>-0.012540</td>\n",
       "      <td>-0.016711</td>\n",
       "      <td>-0.006777</td>\n",
       "      <td>0.001336</td>\n",
       "      <td>-0.001685</td>\n",
       "      <td>0.009508</td>\n",
       "      <td>0.000790</td>\n",
       "      <td>0.003174</td>\n",
       "      <td>0.008983</td>\n",
       "      <td>0.015720</td>\n",
       "      <td>0.000909</td>\n",
       "      <td>-0.000162</td>\n",
       "      <td>-0.009881</td>\n",
       "      <td>0.014723</td>\n",
       "      <td>-0.012467</td>\n",
       "      <td>-0.003250</td>\n",
       "      <td>-0.003016</td>\n",
       "      <td>-0.011085</td>\n",
       "      <td>-0.015328</td>\n",
       "      <td>0.007870</td>\n",
       "      <td>0.008461</td>\n",
       "      <td>-0.003044</td>\n",
       "      <td>-0.017816</td>\n",
       "      <td>0.005057</td>\n",
       "      <td>-0.002679</td>\n",
       "      <td>-0.004189</td>\n",
       "      <td>-0.016218</td>\n",
       "      <td>0.004340</td>\n",
       "      <td>-0.003966</td>\n",
       "      <td>-0.001803</td>\n",
       "      <td>-0.005356</td>\n",
       "      <td>-0.000749</td>\n",
       "      <td>0.005549</td>\n",
       "      <td>-0.003596</td>\n",
       "      <td>-0.011181</td>\n",
       "      <td>-0.008410</td>\n",
       "      <td>-0.008732</td>\n",
       "      <td>0.001223</td>\n",
       "      <td>0.005539</td>\n",
       "      <td>-0.012825</td>\n",
       "      <td>-0.007292</td>\n",
       "      <td>-0.014062</td>\n",
       "      <td>0.007041</td>\n",
       "      <td>0.000488</td>\n",
       "      <td>0.012103</td>\n",
       "      <td>-0.000710</td>\n",
       "      <td>0.003932</td>\n",
       "      <td>0.001086</td>\n",
       "      <td>0.008904</td>\n",
       "      <td>0.004828</td>\n",
       "      <td>0.002650</td>\n",
       "      <td>0.019244</td>\n",
       "      <td>-0.010806</td>\n",
       "      <td>-0.003380</td>\n",
       "      <td>0.010062</td>\n",
       "      <td>-0.003819</td>\n",
       "      <td>0.003893</td>\n",
       "      <td>-0.002207</td>\n",
       "      <td>-0.002617</td>\n",
       "      <td>0.003910</td>\n",
       "      <td>-0.018076</td>\n",
       "      <td>-0.011648</td>\n",
       "      <td>-0.009684</td>\n",
       "      <td>-0.003181</td>\n",
       "      <td>0.004471</td>\n",
       "      <td>-0.003760</td>\n",
       "      <td>-0.004021</td>\n",
       "      <td>0.000293</td>\n",
       "      <td>0.008409</td>\n",
       "      <td>0.001463</td>\n",
       "      <td>0.000249</td>\n",
       "      <td>-0.020276</td>\n",
       "      <td>0.012677</td>\n",
       "      <td>-0.012528</td>\n",
       "      <td>-0.000843</td>\n",
       "      <td>-0.015399</td>\n",
       "      <td>-0.009786</td>\n",
       "      <td>0.001590</td>\n",
       "      <td>0.005269</td>\n",
       "      <td>0.010376</td>\n",
       "      <td>0.001267</td>\n",
       "      <td>-0.010374</td>\n",
       "      <td>-0.009790</td>\n",
       "      <td>-0.005820</td>\n",
       "      <td>-0.006396</td>\n",
       "      <td>-0.088701</td>\n",
       "      <td>-0.009207</td>\n",
       "      <td>0.000503</td>\n",
       "      <td>-0.000050</td>\n",
       "      <td>-0.009159</td>\n",
       "      <td>-0.009715</td>\n",
       "      <td>-0.002142</td>\n",
       "      <td>0.000194</td>\n",
       "      <td>0.004746</td>\n",
       "      <td>-0.013538</td>\n",
       "      <td>-0.000488</td>\n",
       "      <td>0.010173</td>\n",
       "      <td>-0.003365</td>\n",
       "      <td>0.015203</td>\n",
       "      <td>0.008147</td>\n",
       "      <td>0.005277</td>\n",
       "      <td>0.001525</td>\n",
       "      <td>0.009584</td>\n",
       "      <td>-0.003005</td>\n",
       "      <td>-0.005656</td>\n",
       "      <td>-0.002186</td>\n",
       "      <td>-0.014849</td>\n",
       "      <td>-0.005132</td>\n",
       "      <td>-0.002130</td>\n",
       "      <td>-0.006065</td>\n",
       "      <td>-0.010093</td>\n",
       "      <td>0.014281</td>\n",
       "      <td>0.006598</td>\n",
       "      <td>0.013746</td>\n",
       "      <td>0.006167</td>\n",
       "      <td>0.010814</td>\n",
       "      <td>-0.005055</td>\n",
       "      <td>0.020368</td>\n",
       "      <td>0.000943</td>\n",
       "      <td>-0.004726</td>\n",
       "      <td>0.004315</td>\n",
       "      <td>-0.008697</td>\n",
       "      <td>-0.001492</td>\n",
       "      <td>0.012311</td>\n",
       "      <td>0.006620</td>\n",
       "      <td>-0.003384</td>\n",
       "      <td>-0.000943</td>\n",
       "      <td>0.010286</td>\n",
       "      <td>-0.003920</td>\n",
       "      <td>-0.000030</td>\n",
       "      <td>-0.002571</td>\n",
       "      <td>0.002520</td>\n",
       "      <td>-0.015289</td>\n",
       "      <td>0.005796</td>\n",
       "      <td>0.009802</td>\n",
       "      <td>0.010031</td>\n",
       "      <td>-0.016055</td>\n",
       "      <td>-0.002525</td>\n",
       "      <td>-0.009154</td>\n",
       "      <td>0.009209</td>\n",
       "      <td>-0.015437</td>\n",
       "      <td>-0.007777</td>\n",
       "      <td>-0.012085</td>\n",
       "      <td>0.002940</td>\n",
       "      <td>0.006084</td>\n",
       "      <td>0.013671</td>\n",
       "      <td>0.000197</td>\n",
       "      <td>0.005658</td>\n",
       "      <td>-0.026751</td>\n",
       "      <td>-0.005343</td>\n",
       "      <td>0.007512</td>\n",
       "      <td>0.002361</td>\n",
       "      <td>0.003925</td>\n",
       "      <td>0.003020</td>\n",
       "      <td>0.003008</td>\n",
       "      <td>0.022163</td>\n",
       "      <td>0.012650</td>\n",
       "      <td>-0.015703</td>\n",
       "      <td>-0.004107</td>\n",
       "      <td>0.005260</td>\n",
       "      <td>0.009882</td>\n",
       "      <td>-0.012031</td>\n",
       "      <td>-0.003147</td>\n",
       "      <td>0.004494</td>\n",
       "      <td>0.009656</td>\n",
       "      <td>-0.003146</td>\n",
       "      <td>-0.009368</td>\n",
       "      <td>0.000697</td>\n",
       "      <td>-0.002360</td>\n",
       "      <td>-0.000860</td>\n",
       "      <td>-0.001608</td>\n",
       "      <td>-0.004402</td>\n",
       "      <td>-0.005496</td>\n",
       "      <td>0.003044</td>\n",
       "      <td>-0.008543</td>\n",
       "      <td>-0.010125</td>\n",
       "      <td>0.004312</td>\n",
       "      <td>0.010165</td>\n",
       "      <td>0.006160</td>\n",
       "      <td>-0.001559</td>\n",
       "      <td>0.009150</td>\n",
       "      <td>-0.006231</td>\n",
       "      <td>0.014016</td>\n",
       "      <td>-0.005033</td>\n",
       "      <td>0.004038</td>\n",
       "      <td>-0.005541</td>\n",
       "      <td>0.004458</td>\n",
       "      <td>0.004672</td>\n",
       "      <td>-0.008524</td>\n",
       "      <td>-0.000446</td>\n",
       "      <td>0.003886</td>\n",
       "      <td>-0.011758</td>\n",
       "      <td>-0.006797</td>\n",
       "      <td>-0.014141</td>\n",
       "      <td>-0.006321</td>\n",
       "      <td>0.001055</td>\n",
       "      <td>0.008618</td>\n",
       "      <td>0.008851</td>\n",
       "      <td>0.001085</td>\n",
       "      <td>0.002576</td>\n",
       "      <td>-0.026481</td>\n",
       "      <td>0.003643</td>\n",
       "      <td>-0.000586</td>\n",
       "      <td>-0.004493</td>\n",
       "      <td>-0.002354</td>\n",
       "      <td>0.012792</td>\n",
       "      <td>0.004118</td>\n",
       "      <td>0.014548</td>\n",
       "      <td>-0.003366</td>\n",
       "      <td>-0.009376</td>\n",
       "      <td>-0.005777</td>\n",
       "      <td>-0.000153</td>\n",
       "      <td>0.008690</td>\n",
       "      <td>0.018885</td>\n",
       "      <td>-0.005637</td>\n",
       "      <td>-0.002932</td>\n",
       "      <td>0.002414</td>\n",
       "      <td>0.006981</td>\n",
       "      <td>-0.004953</td>\n",
       "      <td>-0.009645</td>\n",
       "      <td>-0.007002</td>\n",
       "      <td>0.015099</td>\n",
       "      <td>0.003680</td>\n",
       "      <td>0.005166</td>\n",
       "      <td>-0.000422</td>\n",
       "      <td>-0.003926</td>\n",
       "      <td>-0.002706</td>\n",
       "      <td>-0.006051</td>\n",
       "      <td>-0.018612</td>\n",
       "      <td>0.005620</td>\n",
       "      <td>-0.006797</td>\n",
       "      <td>-0.003928</td>\n",
       "      <td>0.003207</td>\n",
       "      <td>-0.011927</td>\n",
       "      <td>-0.001529</td>\n",
       "      <td>0.009228</td>\n",
       "      <td>0.004600</td>\n",
       "      <td>0.007397</td>\n",
       "      <td>-0.005580</td>\n",
       "      <td>0.002534</td>\n",
       "      <td>0.003226</td>\n",
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       "      <td>-0.003271</td>\n",
       "      <td>0.010530</td>\n",
       "      <td>-0.012191</td>\n",
       "      <td>0.005421</td>\n",
       "      <td>-0.006576</td>\n",
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       "      <td>0.001385</td>\n",
       "      <td>-0.012464</td>\n",
       "      <td>-0.002598</td>\n",
       "      <td>-0.013499</td>\n",
       "      <td>-0.010528</td>\n",
       "      <td>0.000303</td>\n",
       "      <td>0.015255</td>\n",
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       "      <td>-0.000263</td>\n",
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       "      <td>-0.000798</td>\n",
       "      <td>-0.003185</td>\n",
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       "      <td>-0.014428</td>\n",
       "      <td>-0.004167</td>\n",
       "      <td>-0.017179</td>\n",
       "      <td>0.000279</td>\n",
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       "      <td>0.008407</td>\n",
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       "      <td>0.001245</td>\n",
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       "      <td>-0.002069</td>\n",
       "      <td>-0.000820</td>\n",
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       "      <td>-0.002378</td>\n",
       "      <td>0.000204</td>\n",
       "      <td>0.001602</td>\n",
       "      <td>-0.000427</td>\n",
       "      <td>0.003871</td>\n",
       "      <td>0.011190</td>\n",
       "      <td>-0.000533</td>\n",
       "      <td>-0.008234</td>\n",
       "      <td>-0.001427</td>\n",
       "      <td>-0.007397</td>\n",
       "      <td>0.009120</td>\n",
       "      <td>-0.003209</td>\n",
       "      <td>0.013885</td>\n",
       "      <td>0.013373</td>\n",
       "      <td>0.004734</td>\n",
       "      <td>-0.015384</td>\n",
       "      <td>0.000503</td>\n",
       "      <td>-0.010901</td>\n",
       "      <td>0.007405</td>\n",
       "      <td>-0.013878</td>\n",
       "      <td>0.010089</td>\n",
       "      <td>0.007520</td>\n",
       "      <td>0.004323</td>\n",
       "      <td>-0.007298</td>\n",
       "      <td>-0.007975</td>\n",
       "      <td>0.003294</td>\n",
       "      <td>-0.014838</td>\n",
       "      <td>-0.004809</td>\n",
       "      <td>0.013251</td>\n",
       "      <td>0.002273</td>\n",
       "      <td>-0.013875</td>\n",
       "      <td>0.012669</td>\n",
       "      <td>0.002175</td>\n",
       "      <td>-0.005167</td>\n",
       "      <td>0.008062</td>\n",
       "      <td>0.001263</td>\n",
       "      <td>0.012151</td>\n",
       "      <td>0.008454</td>\n",
       "      <td>0.001987</td>\n",
       "      <td>0.004420</td>\n",
       "      <td>0.013856</td>\n",
       "      <td>-0.015964</td>\n",
       "      <td>-0.004239</td>\n",
       "      <td>-0.000673</td>\n",
       "      <td>0.001831</td>\n",
       "      <td>0.012577</td>\n",
       "      <td>0.008599</td>\n",
       "      <td>-0.010648</td>\n",
       "      <td>-0.012607</td>\n",
       "      <td>0.003760</td>\n",
       "      <td>-0.004256</td>\n",
       "      <td>-0.007629</td>\n",
       "      <td>-0.017924</td>\n",
       "      <td>-0.010815</td>\n",
       "      <td>-0.019907</td>\n",
       "      <td>0.012008</td>\n",
       "      <td>-0.008528</td>\n",
       "      <td>-0.000311</td>\n",
       "      <td>-0.012759</td>\n",
       "      <td>0.007218</td>\n",
       "      <td>0.013702</td>\n",
       "      <td>-0.009488</td>\n",
       "      <td>0.015019</td>\n",
       "      <td>0.008593</td>\n",
       "      <td>0.002801</td>\n",
       "      <td>-0.009177</td>\n",
       "      <td>0.002372</td>\n",
       "      <td>0.007718</td>\n",
       "      <td>-0.002499</td>\n",
       "      <td>-0.001699</td>\n",
       "      <td>0.010950</td>\n",
       "      <td>0.005768</td>\n",
       "      <td>0.012455</td>\n",
       "      <td>-0.011750</td>\n",
       "      <td>0.000152</td>\n",
       "      <td>-0.001383</td>\n",
       "      <td>0.001503</td>\n",
       "      <td>0.000125</td>\n",
       "      <td>0.002739</td>\n",
       "      <td>0.003896</td>\n",
       "      <td>0.002257</td>\n",
       "      <td>0.000117</td>\n",
       "      <td>0.001191</td>\n",
       "      <td>0.001902</td>\n",
       "      <td>0.002014</td>\n",
       "      <td>0.011581</td>\n",
       "      <td>0.003535</td>\n",
       "      <td>-0.001087</td>\n",
       "      <td>0.008272</td>\n",
       "      <td>-0.008000</td>\n",
       "      <td>0.013401</td>\n",
       "      <td>0.011201</td>\n",
       "      <td>0.017522</td>\n",
       "      <td>0.004555</td>\n",
       "      <td>0.005950</td>\n",
       "      <td>0.012293</td>\n",
       "      <td>0.007061</td>\n",
       "      <td>0.015052</td>\n",
       "      <td>0.005686</td>\n",
       "      <td>-0.004272</td>\n",
       "      <td>-0.002284</td>\n",
       "      <td>-0.008144</td>\n",
       "      <td>-0.006011</td>\n",
       "      <td>-0.013858</td>\n",
       "      <td>0.007633</td>\n",
       "      <td>0.006829</td>\n",
       "      <td>0.002105</td>\n",
       "      <td>0.013005</td>\n",
       "      <td>-0.004089</td>\n",
       "      <td>0.000854</td>\n",
       "      <td>0.002546</td>\n",
       "      <td>-0.000919</td>\n",
       "      <td>0.010651</td>\n",
       "      <td>0.005651</td>\n",
       "      <td>0.009712</td>\n",
       "      <td>-0.014924</td>\n",
       "      <td>0.016957</td>\n",
       "      <td>-0.003413</td>\n",
       "      <td>0.003462</td>\n",
       "      <td>-0.003335</td>\n",
       "      <td>-0.000140</td>\n",
       "      <td>-0.014230</td>\n",
       "      <td>-0.009615</td>\n",
       "      <td>-0.018324</td>\n",
       "      <td>-0.003666</td>\n",
       "      <td>-0.004091</td>\n",
       "      <td>0.000284</td>\n",
       "      <td>-0.001322</td>\n",
       "      <td>-0.010377</td>\n",
       "      <td>0.007259</td>\n",
       "      <td>-0.004348</td>\n",
       "      <td>-0.000583</td>\n",
       "      <td>-0.001144</td>\n",
       "      <td>-0.003976</td>\n",
       "      <td>0.002217</td>\n",
       "      <td>0.000805</td>\n",
       "      <td>-0.007403</td>\n",
       "      <td>0.000737</td>\n",
       "      <td>0.002015</td>\n",
       "      <td>-0.009409</td>\n",
       "      <td>-0.002301</td>\n",
       "      <td>0.007608</td>\n",
       "      <td>0.011130</td>\n",
       "      <td>0.005080</td>\n",
       "      <td>0.003854</td>\n",
       "      <td>-0.003946</td>\n",
       "      <td>-0.004238</td>\n",
       "      <td>0.003537</td>\n",
       "      <td>-0.003510</td>\n",
       "      <td>0.002733</td>\n",
       "      <td>0.003851</td>\n",
       "      <td>-0.021861</td>\n",
       "      <td>-0.013896</td>\n",
       "      <td>-0.003653</td>\n",
       "      <td>0.011166</td>\n",
       "      <td>-0.012583</td>\n",
       "      <td>-0.003350</td>\n",
       "      <td>7.0</td>\n",
       "      <td>63</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3732</th>\n",
       "      <td>-0.016595</td>\n",
       "      <td>0.008654</td>\n",
       "      <td>0.009148</td>\n",
       "      <td>-0.005493</td>\n",
       "      <td>-0.001894</td>\n",
       "      <td>0.002628</td>\n",
       "      <td>-0.014169</td>\n",
       "      <td>-0.014779</td>\n",
       "      <td>-0.007168</td>\n",
       "      <td>-0.001789</td>\n",
       "      <td>0.006362</td>\n",
       "      <td>0.000314</td>\n",
       "      <td>-0.003315</td>\n",
       "      <td>0.006398</td>\n",
       "      <td>-0.006350</td>\n",
       "      <td>-0.007348</td>\n",
       "      <td>0.011564</td>\n",
       "      <td>0.001449</td>\n",
       "      <td>-0.002290</td>\n",
       "      <td>0.012800</td>\n",
       "      <td>0.000849</td>\n",
       "      <td>0.013553</td>\n",
       "      <td>-0.019136</td>\n",
       "      <td>0.010726</td>\n",
       "      <td>-0.005807</td>\n",
       "      <td>0.005303</td>\n",
       "      <td>0.010414</td>\n",
       "      <td>0.016278</td>\n",
       "      <td>0.010089</td>\n",
       "      <td>0.001871</td>\n",
       "      <td>-0.013602</td>\n",
       "      <td>-0.027194</td>\n",
       "      <td>0.011761</td>\n",
       "      <td>-0.005217</td>\n",
       "      <td>0.000503</td>\n",
       "      <td>0.010388</td>\n",
       "      <td>0.009803</td>\n",
       "      <td>0.003312</td>\n",
       "      <td>-0.014931</td>\n",
       "      <td>-0.009624</td>\n",
       "      <td>0.001285</td>\n",
       "      <td>-0.018581</td>\n",
       "      <td>-0.010090</td>\n",
       "      <td>0.024998</td>\n",
       "      <td>0.006007</td>\n",
       "      <td>0.016121</td>\n",
       "      <td>0.004461</td>\n",
       "      <td>0.009184</td>\n",
       "      <td>0.012555</td>\n",
       "      <td>0.002390</td>\n",
       "      <td>-0.019372</td>\n",
       "      <td>0.004416</td>\n",
       "      <td>0.010102</td>\n",
       "      <td>-0.003217</td>\n",
       "      <td>-0.003456</td>\n",
       "      <td>0.000066</td>\n",
       "      <td>-0.002271</td>\n",
       "      <td>-0.012721</td>\n",
       "      <td>0.018290</td>\n",
       "      <td>-0.010729</td>\n",
       "      <td>0.001988</td>\n",
       "      <td>0.001770</td>\n",
       "      <td>-0.024568</td>\n",
       "      <td>0.010619</td>\n",
       "      <td>-0.014107</td>\n",
       "      <td>0.004676</td>\n",
       "      <td>-0.011958</td>\n",
       "      <td>0.001761</td>\n",
       "      <td>0.018364</td>\n",
       "      <td>-0.013275</td>\n",
       "      <td>-0.006591</td>\n",
       "      <td>-0.011522</td>\n",
       "      <td>0.000835</td>\n",
       "      <td>0.005047</td>\n",
       "      <td>-0.011516</td>\n",
       "      <td>-0.011753</td>\n",
       "      <td>0.016469</td>\n",
       "      <td>-0.007339</td>\n",
       "      <td>0.012844</td>\n",
       "      <td>-0.005266</td>\n",
       "      <td>-0.011977</td>\n",
       "      <td>0.017150</td>\n",
       "      <td>0.002303</td>\n",
       "      <td>-0.006094</td>\n",
       "      <td>-0.000440</td>\n",
       "      <td>-0.019107</td>\n",
       "      <td>-0.002151</td>\n",
       "      <td>0.002496</td>\n",
       "      <td>-0.013628</td>\n",
       "      <td>-0.034850</td>\n",
       "      <td>-0.011237</td>\n",
       "      <td>0.014332</td>\n",
       "      <td>0.008100</td>\n",
       "      <td>-0.008833</td>\n",
       "      <td>-0.001671</td>\n",
       "      <td>0.001229</td>\n",
       "      <td>-0.008469</td>\n",
       "      <td>0.014049</td>\n",
       "      <td>0.019063</td>\n",
       "      <td>-0.009205</td>\n",
       "      <td>-0.017206</td>\n",
       "      <td>0.010377</td>\n",
       "      <td>-0.006699</td>\n",
       "      <td>0.010292</td>\n",
       "      <td>0.002353</td>\n",
       "      <td>0.003203</td>\n",
       "      <td>0.001729</td>\n",
       "      <td>-0.031671</td>\n",
       "      <td>-0.000166</td>\n",
       "      <td>0.004591</td>\n",
       "      <td>0.013195</td>\n",
       "      <td>-0.001430</td>\n",
       "      <td>-0.018670</td>\n",
       "      <td>-0.003304</td>\n",
       "      <td>-0.001970</td>\n",
       "      <td>-0.014481</td>\n",
       "      <td>0.010218</td>\n",
       "      <td>0.012360</td>\n",
       "      <td>0.003092</td>\n",
       "      <td>0.022095</td>\n",
       "      <td>0.013556</td>\n",
       "      <td>-0.003933</td>\n",
       "      <td>0.004627</td>\n",
       "      <td>-0.001145</td>\n",
       "      <td>0.012032</td>\n",
       "      <td>0.002315</td>\n",
       "      <td>-0.003432</td>\n",
       "      <td>0.016435</td>\n",
       "      <td>-0.006083</td>\n",
       "      <td>-0.001418</td>\n",
       "      <td>0.010155</td>\n",
       "      <td>-0.000679</td>\n",
       "      <td>0.006938</td>\n",
       "      <td>0.009583</td>\n",
       "      <td>-0.013079</td>\n",
       "      <td>-0.005077</td>\n",
       "      <td>0.012050</td>\n",
       "      <td>0.008688</td>\n",
       "      <td>0.005268</td>\n",
       "      <td>-0.020090</td>\n",
       "      <td>-0.000855</td>\n",
       "      <td>0.020139</td>\n",
       "      <td>0.014240</td>\n",
       "      <td>0.007505</td>\n",
       "      <td>0.003426</td>\n",
       "      <td>-0.000142</td>\n",
       "      <td>-0.004549</td>\n",
       "      <td>-0.007838</td>\n",
       "      <td>0.014188</td>\n",
       "      <td>0.003207</td>\n",
       "      <td>0.008977</td>\n",
       "      <td>-0.002974</td>\n",
       "      <td>-0.005526</td>\n",
       "      <td>0.003672</td>\n",
       "      <td>0.009672</td>\n",
       "      <td>-0.010718</td>\n",
       "      <td>-0.017338</td>\n",
       "      <td>-0.001117</td>\n",
       "      <td>0.015449</td>\n",
       "      <td>0.005066</td>\n",
       "      <td>-0.019222</td>\n",
       "      <td>0.005699</td>\n",
       "      <td>-0.002498</td>\n",
       "      <td>-0.012049</td>\n",
       "      <td>0.020929</td>\n",
       "      <td>0.007751</td>\n",
       "      <td>-0.003583</td>\n",
       "      <td>-0.003159</td>\n",
       "      <td>-0.010841</td>\n",
       "      <td>-0.001117</td>\n",
       "      <td>-0.002337</td>\n",
       "      <td>0.018327</td>\n",
       "      <td>0.007435</td>\n",
       "      <td>0.004053</td>\n",
       "      <td>0.011110</td>\n",
       "      <td>0.000133</td>\n",
       "      <td>-0.004431</td>\n",
       "      <td>0.019085</td>\n",
       "      <td>0.000372</td>\n",
       "      <td>-0.004825</td>\n",
       "      <td>0.018926</td>\n",
       "      <td>0.005251</td>\n",
       "      <td>0.010804</td>\n",
       "      <td>-0.011814</td>\n",
       "      <td>-0.025145</td>\n",
       "      <td>-0.023071</td>\n",
       "      <td>-0.002068</td>\n",
       "      <td>-0.013540</td>\n",
       "      <td>-0.017623</td>\n",
       "      <td>-0.011473</td>\n",
       "      <td>0.006998</td>\n",
       "      <td>0.001307</td>\n",
       "      <td>-0.010179</td>\n",
       "      <td>0.000029</td>\n",
       "      <td>-0.012880</td>\n",
       "      <td>0.007577</td>\n",
       "      <td>-0.015883</td>\n",
       "      <td>0.008198</td>\n",
       "      <td>0.017956</td>\n",
       "      <td>0.024764</td>\n",
       "      <td>-0.020925</td>\n",
       "      <td>-0.017845</td>\n",
       "      <td>0.003839</td>\n",
       "      <td>-0.001957</td>\n",
       "      <td>-0.014348</td>\n",
       "      <td>0.009890</td>\n",
       "      <td>-0.014753</td>\n",
       "      <td>-0.012890</td>\n",
       "      <td>-0.004232</td>\n",
       "      <td>-0.001432</td>\n",
       "      <td>-0.000821</td>\n",
       "      <td>0.009795</td>\n",
       "      <td>0.002814</td>\n",
       "      <td>-0.013248</td>\n",
       "      <td>-0.000909</td>\n",
       "      <td>0.006473</td>\n",
       "      <td>-0.016481</td>\n",
       "      <td>0.004541</td>\n",
       "      <td>0.009552</td>\n",
       "      <td>0.019166</td>\n",
       "      <td>0.000422</td>\n",
       "      <td>-0.007727</td>\n",
       "      <td>-0.022280</td>\n",
       "      <td>-0.001256</td>\n",
       "      <td>-0.007679</td>\n",
       "      <td>-0.008628</td>\n",
       "      <td>-0.017947</td>\n",
       "      <td>-0.037143</td>\n",
       "      <td>0.002134</td>\n",
       "      <td>0.002289</td>\n",
       "      <td>-0.000842</td>\n",
       "      <td>0.005959</td>\n",
       "      <td>-0.003979</td>\n",
       "      <td>-0.004614</td>\n",
       "      <td>-0.025517</td>\n",
       "      <td>-0.007473</td>\n",
       "      <td>0.003903</td>\n",
       "      <td>-0.001601</td>\n",
       "      <td>-0.007581</td>\n",
       "      <td>-0.025185</td>\n",
       "      <td>-0.004831</td>\n",
       "      <td>-0.020322</td>\n",
       "      <td>0.001702</td>\n",
       "      <td>0.010883</td>\n",
       "      <td>0.005525</td>\n",
       "      <td>0.012660</td>\n",
       "      <td>-0.011589</td>\n",
       "      <td>0.017275</td>\n",
       "      <td>0.004415</td>\n",
       "      <td>0.004056</td>\n",
       "      <td>0.002603</td>\n",
       "      <td>-0.007437</td>\n",
       "      <td>0.003675</td>\n",
       "      <td>0.001943</td>\n",
       "      <td>0.009161</td>\n",
       "      <td>-0.008587</td>\n",
       "      <td>-0.012396</td>\n",
       "      <td>-0.002843</td>\n",
       "      <td>0.019132</td>\n",
       "      <td>0.012000</td>\n",
       "      <td>-0.009684</td>\n",
       "      <td>-0.012039</td>\n",
       "      <td>-0.006680</td>\n",
       "      <td>-0.001790</td>\n",
       "      <td>0.018292</td>\n",
       "      <td>-0.022296</td>\n",
       "      <td>0.005157</td>\n",
       "      <td>-0.001707</td>\n",
       "      <td>0.006351</td>\n",
       "      <td>0.008771</td>\n",
       "      <td>-0.008673</td>\n",
       "      <td>-0.010671</td>\n",
       "      <td>-0.000591</td>\n",
       "      <td>0.001622</td>\n",
       "      <td>0.016295</td>\n",
       "      <td>0.014802</td>\n",
       "      <td>0.004607</td>\n",
       "      <td>-0.013932</td>\n",
       "      <td>-0.007337</td>\n",
       "      <td>0.005913</td>\n",
       "      <td>-0.003418</td>\n",
       "      <td>0.004262</td>\n",
       "      <td>0.011847</td>\n",
       "      <td>0.005778</td>\n",
       "      <td>-0.010248</td>\n",
       "      <td>0.014652</td>\n",
       "      <td>-0.010894</td>\n",
       "      <td>0.005203</td>\n",
       "      <td>0.002770</td>\n",
       "      <td>-0.017036</td>\n",
       "      <td>0.000066</td>\n",
       "      <td>-0.001110</td>\n",
       "      <td>0.002461</td>\n",
       "      <td>0.000046</td>\n",
       "      <td>0.002126</td>\n",
       "      <td>-0.003464</td>\n",
       "      <td>0.003140</td>\n",
       "      <td>0.003174</td>\n",
       "      <td>-0.010905</td>\n",
       "      <td>0.007722</td>\n",
       "      <td>-0.008559</td>\n",
       "      <td>0.021996</td>\n",
       "      <td>0.010008</td>\n",
       "      <td>0.020515</td>\n",
       "      <td>0.002539</td>\n",
       "      <td>0.004955</td>\n",
       "      <td>-0.001473</td>\n",
       "      <td>0.011002</td>\n",
       "      <td>0.009195</td>\n",
       "      <td>-0.010015</td>\n",
       "      <td>0.016480</td>\n",
       "      <td>-0.002444</td>\n",
       "      <td>0.005021</td>\n",
       "      <td>-0.009228</td>\n",
       "      <td>0.010244</td>\n",
       "      <td>0.002444</td>\n",
       "      <td>-0.015393</td>\n",
       "      <td>-0.012663</td>\n",
       "      <td>0.004703</td>\n",
       "      <td>0.004682</td>\n",
       "      <td>-0.004351</td>\n",
       "      <td>0.000899</td>\n",
       "      <td>0.019752</td>\n",
       "      <td>-0.014971</td>\n",
       "      <td>-0.009357</td>\n",
       "      <td>-0.018577</td>\n",
       "      <td>-0.005397</td>\n",
       "      <td>0.008812</td>\n",
       "      <td>-0.003971</td>\n",
       "      <td>0.001316</td>\n",
       "      <td>0.018620</td>\n",
       "      <td>0.008415</td>\n",
       "      <td>0.013638</td>\n",
       "      <td>0.004677</td>\n",
       "      <td>0.007945</td>\n",
       "      <td>0.008845</td>\n",
       "      <td>0.014564</td>\n",
       "      <td>-0.016346</td>\n",
       "      <td>0.002480</td>\n",
       "      <td>0.004830</td>\n",
       "      <td>-0.003452</td>\n",
       "      <td>-0.006701</td>\n",
       "      <td>-0.021576</td>\n",
       "      <td>0.013429</td>\n",
       "      <td>0.001949</td>\n",
       "      <td>-0.002483</td>\n",
       "      <td>-0.006322</td>\n",
       "      <td>0.004356</td>\n",
       "      <td>-0.012696</td>\n",
       "      <td>0.007886</td>\n",
       "      <td>0.012289</td>\n",
       "      <td>0.010349</td>\n",
       "      <td>0.006508</td>\n",
       "      <td>-0.006639</td>\n",
       "      <td>0.003261</td>\n",
       "      <td>0.001961</td>\n",
       "      <td>0.004565</td>\n",
       "      <td>-0.017207</td>\n",
       "      <td>0.001639</td>\n",
       "      <td>0.010086</td>\n",
       "      <td>-0.010535</td>\n",
       "      <td>0.019887</td>\n",
       "      <td>0.003894</td>\n",
       "      <td>0.007694</td>\n",
       "      <td>-0.004135</td>\n",
       "      <td>0.008260</td>\n",
       "      <td>-0.002455</td>\n",
       "      <td>-0.001802</td>\n",
       "      <td>0.000866</td>\n",
       "      <td>-0.015609</td>\n",
       "      <td>0.012888</td>\n",
       "      <td>0.006018</td>\n",
       "      <td>0.017801</td>\n",
       "      <td>-0.021405</td>\n",
       "      <td>0.015659</td>\n",
       "      <td>-0.010653</td>\n",
       "      <td>0.012094</td>\n",
       "      <td>-0.007717</td>\n",
       "      <td>0.032641</td>\n",
       "      <td>0.013207</td>\n",
       "      <td>-0.000369</td>\n",
       "      <td>-0.018693</td>\n",
       "      <td>-0.001221</td>\n",
       "      <td>0.006062</td>\n",
       "      <td>0.001332</td>\n",
       "      <td>0.001256</td>\n",
       "      <td>0.000121</td>\n",
       "      <td>-0.009742</td>\n",
       "      <td>-0.024610</td>\n",
       "      <td>0.006930</td>\n",
       "      <td>0.022306</td>\n",
       "      <td>0.029941</td>\n",
       "      <td>0.013145</td>\n",
       "      <td>-0.000021</td>\n",
       "      <td>0.004163</td>\n",
       "      <td>-0.001029</td>\n",
       "      <td>-0.004920</td>\n",
       "      <td>-0.010422</td>\n",
       "      <td>-0.017993</td>\n",
       "      <td>-0.003113</td>\n",
       "      <td>-0.010774</td>\n",
       "      <td>-0.010129</td>\n",
       "      <td>0.004964</td>\n",
       "      <td>-0.007793</td>\n",
       "      <td>-0.004282</td>\n",
       "      <td>-0.003061</td>\n",
       "      <td>-0.006599</td>\n",
       "      <td>-0.002866</td>\n",
       "      <td>0.002173</td>\n",
       "      <td>-0.014331</td>\n",
       "      <td>-0.001790</td>\n",
       "      <td>-0.005916</td>\n",
       "      <td>-0.008464</td>\n",
       "      <td>0.010317</td>\n",
       "      <td>-0.008868</td>\n",
       "      <td>-0.001481</td>\n",
       "      <td>-0.009951</td>\n",
       "      <td>0.005717</td>\n",
       "      <td>-0.011056</td>\n",
       "      <td>-0.028506</td>\n",
       "      <td>-0.010931</td>\n",
       "      <td>-0.007888</td>\n",
       "      <td>-0.015503</td>\n",
       "      <td>-0.020673</td>\n",
       "      <td>0.000117</td>\n",
       "      <td>0.010678</td>\n",
       "      <td>-0.012382</td>\n",
       "      <td>-0.011516</td>\n",
       "      <td>-0.008335</td>\n",
       "      <td>-0.003936</td>\n",
       "      <td>-0.000916</td>\n",
       "      <td>0.003030</td>\n",
       "      <td>-0.005316</td>\n",
       "      <td>0.001894</td>\n",
       "      <td>-0.000108</td>\n",
       "      <td>-0.013475</td>\n",
       "      <td>0.030931</td>\n",
       "      <td>0.004079</td>\n",
       "      <td>0.032401</td>\n",
       "      <td>0.002906</td>\n",
       "      <td>0.003396</td>\n",
       "      <td>0.017955</td>\n",
       "      <td>0.018098</td>\n",
       "      <td>0.004536</td>\n",
       "      <td>0.012333</td>\n",
       "      <td>0.006470</td>\n",
       "      <td>-0.001719</td>\n",
       "      <td>-0.005484</td>\n",
       "      <td>-0.013527</td>\n",
       "      <td>-0.001450</td>\n",
       "      <td>-0.001449</td>\n",
       "      <td>0.002910</td>\n",
       "      <td>0.012856</td>\n",
       "      <td>0.010790</td>\n",
       "      <td>-0.004167</td>\n",
       "      <td>-0.024683</td>\n",
       "      <td>0.006574</td>\n",
       "      <td>-0.017193</td>\n",
       "      <td>0.000104</td>\n",
       "      <td>-0.005966</td>\n",
       "      <td>-0.021555</td>\n",
       "      <td>-0.012749</td>\n",
       "      <td>0.003234</td>\n",
       "      <td>-0.004941</td>\n",
       "      <td>-0.001311</td>\n",
       "      <td>0.007025</td>\n",
       "      <td>-0.005787</td>\n",
       "      <td>-0.006916</td>\n",
       "      <td>0.006549</td>\n",
       "      <td>-0.011008</td>\n",
       "      <td>0.001999</td>\n",
       "      <td>-0.015398</td>\n",
       "      <td>0.009352</td>\n",
       "      <td>-0.019394</td>\n",
       "      <td>-0.013761</td>\n",
       "      <td>0.013530</td>\n",
       "      <td>0.021384</td>\n",
       "      <td>0.010180</td>\n",
       "      <td>-0.000971</td>\n",
       "      <td>0.003506</td>\n",
       "      <td>0.014560</td>\n",
       "      <td>0.005004</td>\n",
       "      <td>0.011072</td>\n",
       "      <td>0.025217</td>\n",
       "      <td>0.011372</td>\n",
       "      <td>0.010613</td>\n",
       "      <td>-0.005759</td>\n",
       "      <td>-0.010585</td>\n",
       "      <td>-0.000928</td>\n",
       "      <td>0.014250</td>\n",
       "      <td>-0.007672</td>\n",
       "      <td>0.009629</td>\n",
       "      <td>-0.001267</td>\n",
       "      <td>-0.016490</td>\n",
       "      <td>-0.006160</td>\n",
       "      <td>-0.010737</td>\n",
       "      <td>-0.019993</td>\n",
       "      <td>-0.002407</td>\n",
       "      <td>0.016972</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.013100</td>\n",
       "      <td>0.000624</td>\n",
       "      <td>-0.002404</td>\n",
       "      <td>0.002981</td>\n",
       "      <td>0.007122</td>\n",
       "      <td>0.000406</td>\n",
       "      <td>-0.001767</td>\n",
       "      <td>-0.005259</td>\n",
       "      <td>-0.021698</td>\n",
       "      <td>-0.025433</td>\n",
       "      <td>-0.006802</td>\n",
       "      <td>0.003746</td>\n",
       "      <td>-0.004397</td>\n",
       "      <td>0.012926</td>\n",
       "      <td>-0.003999</td>\n",
       "      <td>0.012382</td>\n",
       "      <td>0.011610</td>\n",
       "      <td>0.009668</td>\n",
       "      <td>-0.001853</td>\n",
       "      <td>-0.000958</td>\n",
       "      <td>-0.004254</td>\n",
       "      <td>0.015222</td>\n",
       "      <td>-0.016130</td>\n",
       "      <td>-0.007151</td>\n",
       "      <td>-0.005504</td>\n",
       "      <td>-0.016955</td>\n",
       "      <td>-0.015279</td>\n",
       "      <td>0.012218</td>\n",
       "      <td>0.010812</td>\n",
       "      <td>-0.002164</td>\n",
       "      <td>-0.019149</td>\n",
       "      <td>0.006448</td>\n",
       "      <td>-0.002966</td>\n",
       "      <td>-0.008948</td>\n",
       "      <td>-0.031693</td>\n",
       "      <td>0.015216</td>\n",
       "      <td>-0.005333</td>\n",
       "      <td>0.000337</td>\n",
       "      <td>-0.010212</td>\n",
       "      <td>-0.003538</td>\n",
       "      <td>-0.001369</td>\n",
       "      <td>-0.002443</td>\n",
       "      <td>-0.019411</td>\n",
       "      <td>-0.015162</td>\n",
       "      <td>-0.003484</td>\n",
       "      <td>-0.000846</td>\n",
       "      <td>0.005077</td>\n",
       "      <td>-0.024000</td>\n",
       "      <td>-0.001397</td>\n",
       "      <td>-0.016068</td>\n",
       "      <td>0.005202</td>\n",
       "      <td>0.001788</td>\n",
       "      <td>0.016341</td>\n",
       "      <td>0.002113</td>\n",
       "      <td>0.004559</td>\n",
       "      <td>0.001758</td>\n",
       "      <td>0.014038</td>\n",
       "      <td>0.003426</td>\n",
       "      <td>0.008371</td>\n",
       "      <td>0.022990</td>\n",
       "      <td>-0.025277</td>\n",
       "      <td>0.000965</td>\n",
       "      <td>0.017487</td>\n",
       "      <td>0.000796</td>\n",
       "      <td>0.005498</td>\n",
       "      <td>-0.014430</td>\n",
       "      <td>-0.007339</td>\n",
       "      <td>0.000351</td>\n",
       "      <td>-0.018285</td>\n",
       "      <td>-0.016549</td>\n",
       "      <td>-0.019544</td>\n",
       "      <td>-0.003802</td>\n",
       "      <td>0.006837</td>\n",
       "      <td>0.000597</td>\n",
       "      <td>-0.004795</td>\n",
       "      <td>-0.002122</td>\n",
       "      <td>0.007729</td>\n",
       "      <td>-0.004506</td>\n",
       "      <td>-0.007646</td>\n",
       "      <td>-0.021625</td>\n",
       "      <td>0.026795</td>\n",
       "      <td>-0.024915</td>\n",
       "      <td>-0.003330</td>\n",
       "      <td>-0.022892</td>\n",
       "      <td>-0.008949</td>\n",
       "      <td>0.007582</td>\n",
       "      <td>0.009767</td>\n",
       "      <td>0.008863</td>\n",
       "      <td>-0.002902</td>\n",
       "      <td>-0.019668</td>\n",
       "      <td>-0.015461</td>\n",
       "      <td>0.000769</td>\n",
       "      <td>-0.009565</td>\n",
       "      <td>-0.094702</td>\n",
       "      <td>-0.012075</td>\n",
       "      <td>0.002266</td>\n",
       "      <td>0.003600</td>\n",
       "      <td>-0.009056</td>\n",
       "      <td>-0.014292</td>\n",
       "      <td>0.003195</td>\n",
       "      <td>0.011806</td>\n",
       "      <td>0.011279</td>\n",
       "      <td>-0.013265</td>\n",
       "      <td>-0.002142</td>\n",
       "      <td>0.010131</td>\n",
       "      <td>-0.012343</td>\n",
       "      <td>0.022849</td>\n",
       "      <td>0.001692</td>\n",
       "      <td>0.007245</td>\n",
       "      <td>0.003068</td>\n",
       "      <td>0.005600</td>\n",
       "      <td>-0.006456</td>\n",
       "      <td>-0.000256</td>\n",
       "      <td>-0.005433</td>\n",
       "      <td>-0.009549</td>\n",
       "      <td>-0.011748</td>\n",
       "      <td>-0.001061</td>\n",
       "      <td>-0.003116</td>\n",
       "      <td>-0.014757</td>\n",
       "      <td>0.016029</td>\n",
       "      <td>0.007698</td>\n",
       "      <td>0.019931</td>\n",
       "      <td>0.017631</td>\n",
       "      <td>0.016396</td>\n",
       "      <td>-0.010721</td>\n",
       "      <td>0.033958</td>\n",
       "      <td>0.000765</td>\n",
       "      <td>-0.002637</td>\n",
       "      <td>-0.008896</td>\n",
       "      <td>-0.012439</td>\n",
       "      <td>-0.007250</td>\n",
       "      <td>0.016043</td>\n",
       "      <td>0.012996</td>\n",
       "      <td>-0.004001</td>\n",
       "      <td>0.002799</td>\n",
       "      <td>0.017639</td>\n",
       "      <td>-0.008172</td>\n",
       "      <td>0.001751</td>\n",
       "      <td>0.002841</td>\n",
       "      <td>-0.003056</td>\n",
       "      <td>-0.023030</td>\n",
       "      <td>0.017053</td>\n",
       "      <td>0.013824</td>\n",
       "      <td>0.022626</td>\n",
       "      <td>-0.017240</td>\n",
       "      <td>-0.004917</td>\n",
       "      <td>-0.011054</td>\n",
       "      <td>0.009789</td>\n",
       "      <td>-0.020957</td>\n",
       "      <td>-0.008670</td>\n",
       "      <td>-0.017101</td>\n",
       "      <td>0.002761</td>\n",
       "      <td>0.005584</td>\n",
       "      <td>0.029840</td>\n",
       "      <td>-0.004997</td>\n",
       "      <td>0.009326</td>\n",
       "      <td>-0.029147</td>\n",
       "      <td>0.000692</td>\n",
       "      <td>0.010208</td>\n",
       "      <td>0.018566</td>\n",
       "      <td>0.006080</td>\n",
       "      <td>0.014835</td>\n",
       "      <td>0.001651</td>\n",
       "      <td>0.021805</td>\n",
       "      <td>0.017166</td>\n",
       "      <td>-0.018237</td>\n",
       "      <td>-0.005385</td>\n",
       "      <td>0.001740</td>\n",
       "      <td>0.006459</td>\n",
       "      <td>-0.007206</td>\n",
       "      <td>-0.007421</td>\n",
       "      <td>0.001685</td>\n",
       "      <td>0.012441</td>\n",
       "      <td>0.000132</td>\n",
       "      <td>-0.004736</td>\n",
       "      <td>0.000926</td>\n",
       "      <td>0.007850</td>\n",
       "      <td>-0.002772</td>\n",
       "      <td>0.002083</td>\n",
       "      <td>-0.005950</td>\n",
       "      <td>-0.013209</td>\n",
       "      <td>0.002344</td>\n",
       "      <td>-0.014050</td>\n",
       "      <td>-0.026009</td>\n",
       "      <td>-0.002082</td>\n",
       "      <td>0.015065</td>\n",
       "      <td>0.000443</td>\n",
       "      <td>-0.004564</td>\n",
       "      <td>0.009337</td>\n",
       "      <td>-0.006233</td>\n",
       "      <td>0.015102</td>\n",
       "      <td>-0.003794</td>\n",
       "      <td>-0.005859</td>\n",
       "      <td>-0.014967</td>\n",
       "      <td>-0.007303</td>\n",
       "      <td>0.012076</td>\n",
       "      <td>-0.012833</td>\n",
       "      <td>-0.008719</td>\n",
       "      <td>-0.011926</td>\n",
       "      <td>-0.021319</td>\n",
       "      <td>-0.007824</td>\n",
       "      <td>-0.010065</td>\n",
       "      <td>-0.005763</td>\n",
       "      <td>0.000566</td>\n",
       "      <td>0.007439</td>\n",
       "      <td>0.017264</td>\n",
       "      <td>-0.002576</td>\n",
       "      <td>0.010836</td>\n",
       "      <td>-0.038802</td>\n",
       "      <td>0.002619</td>\n",
       "      <td>-0.002994</td>\n",
       "      <td>-0.002435</td>\n",
       "      <td>-0.005468</td>\n",
       "      <td>0.018599</td>\n",
       "      <td>0.005068</td>\n",
       "      <td>0.019546</td>\n",
       "      <td>0.001423</td>\n",
       "      <td>-0.017245</td>\n",
       "      <td>-0.006852</td>\n",
       "      <td>0.002107</td>\n",
       "      <td>0.011652</td>\n",
       "      <td>0.017299</td>\n",
       "      <td>0.001391</td>\n",
       "      <td>0.006992</td>\n",
       "      <td>0.002753</td>\n",
       "      <td>0.009885</td>\n",
       "      <td>-0.006471</td>\n",
       "      <td>-0.011566</td>\n",
       "      <td>-0.012058</td>\n",
       "      <td>0.026382</td>\n",
       "      <td>0.000984</td>\n",
       "      <td>0.000227</td>\n",
       "      <td>0.002571</td>\n",
       "      <td>-0.004429</td>\n",
       "      <td>0.002642</td>\n",
       "      <td>-0.007165</td>\n",
       "      <td>-0.021826</td>\n",
       "      <td>0.013170</td>\n",
       "      <td>0.000623</td>\n",
       "      <td>-0.007792</td>\n",
       "      <td>0.010359</td>\n",
       "      <td>-0.012550</td>\n",
       "      <td>-0.001098</td>\n",
       "      <td>0.010390</td>\n",
       "      <td>-0.003271</td>\n",
       "      <td>0.007058</td>\n",
       "      <td>-0.005854</td>\n",
       "      <td>0.017258</td>\n",
       "      <td>0.004966</td>\n",
       "      <td>-0.008088</td>\n",
       "      <td>-0.005937</td>\n",
       "      <td>0.008376</td>\n",
       "      <td>-0.019275</td>\n",
       "      <td>0.016451</td>\n",
       "      <td>-0.005743</td>\n",
       "      <td>0.029884</td>\n",
       "      <td>-0.002555</td>\n",
       "      <td>-0.022534</td>\n",
       "      <td>0.002689</td>\n",
       "      <td>-0.011871</td>\n",
       "      <td>-0.011311</td>\n",
       "      <td>0.002567</td>\n",
       "      <td>0.028535</td>\n",
       "      <td>0.006446</td>\n",
       "      <td>0.007631</td>\n",
       "      <td>-0.001049</td>\n",
       "      <td>0.013509</td>\n",
       "      <td>-0.014306</td>\n",
       "      <td>0.003409</td>\n",
       "      <td>-0.005613</td>\n",
       "      <td>0.006671</td>\n",
       "      <td>0.010732</td>\n",
       "      <td>0.004710</td>\n",
       "      <td>0.018928</td>\n",
       "      <td>-0.007619</td>\n",
       "      <td>-0.002958</td>\n",
       "      <td>-0.016103</td>\n",
       "      <td>-0.000340</td>\n",
       "      <td>-0.015794</td>\n",
       "      <td>0.002108</td>\n",
       "      <td>0.002423</td>\n",
       "      <td>-0.004922</td>\n",
       "      <td>-0.016649</td>\n",
       "      <td>0.004355</td>\n",
       "      <td>-0.011956</td>\n",
       "      <td>-0.018321</td>\n",
       "      <td>-0.004920</td>\n",
       "      <td>-0.006050</td>\n",
       "      <td>0.007201</td>\n",
       "      <td>0.001968</td>\n",
       "      <td>0.003428</td>\n",
       "      <td>0.008941</td>\n",
       "      <td>0.005601</td>\n",
       "      <td>0.007466</td>\n",
       "      <td>0.000877</td>\n",
       "      <td>0.005762</td>\n",
       "      <td>-0.022181</td>\n",
       "      <td>0.000850</td>\n",
       "      <td>0.010818</td>\n",
       "      <td>0.011421</td>\n",
       "      <td>-0.002909</td>\n",
       "      <td>-0.006016</td>\n",
       "      <td>0.016933</td>\n",
       "      <td>-0.001340</td>\n",
       "      <td>0.008422</td>\n",
       "      <td>0.006179</td>\n",
       "      <td>0.005942</td>\n",
       "      <td>0.007918</td>\n",
       "      <td>0.004389</td>\n",
       "      <td>0.003493</td>\n",
       "      <td>-0.006422</td>\n",
       "      <td>0.015105</td>\n",
       "      <td>-0.002515</td>\n",
       "      <td>0.005103</td>\n",
       "      <td>-0.001516</td>\n",
       "      <td>-0.004213</td>\n",
       "      <td>-0.002045</td>\n",
       "      <td>-0.005396</td>\n",
       "      <td>0.013854</td>\n",
       "      <td>0.018427</td>\n",
       "      <td>-0.018106</td>\n",
       "      <td>0.007019</td>\n",
       "      <td>-0.000176</td>\n",
       "      <td>0.012725</td>\n",
       "      <td>-0.027523</td>\n",
       "      <td>0.009397</td>\n",
       "      <td>-0.007261</td>\n",
       "      <td>-0.001136</td>\n",
       "      <td>0.017389</td>\n",
       "      <td>0.003879</td>\n",
       "      <td>-0.004570</td>\n",
       "      <td>-0.009426</td>\n",
       "      <td>-0.006834</td>\n",
       "      <td>-0.002359</td>\n",
       "      <td>0.004422</td>\n",
       "      <td>-0.012310</td>\n",
       "      <td>-0.016625</td>\n",
       "      <td>0.000746</td>\n",
       "      <td>-0.007278</td>\n",
       "      <td>-0.013717</td>\n",
       "      <td>-0.009700</td>\n",
       "      <td>0.007763</td>\n",
       "      <td>0.011673</td>\n",
       "      <td>0.008404</td>\n",
       "      <td>0.003669</td>\n",
       "      <td>0.012282</td>\n",
       "      <td>-0.007833</td>\n",
       "      <td>-0.007332</td>\n",
       "      <td>-0.009415</td>\n",
       "      <td>-0.013022</td>\n",
       "      <td>0.016509</td>\n",
       "      <td>-0.007579</td>\n",
       "      <td>0.018860</td>\n",
       "      <td>0.015885</td>\n",
       "      <td>0.007835</td>\n",
       "      <td>-0.014896</td>\n",
       "      <td>0.013266</td>\n",
       "      <td>-0.011979</td>\n",
       "      <td>0.011239</td>\n",
       "      <td>-0.012270</td>\n",
       "      <td>-0.000306</td>\n",
       "      <td>0.006109</td>\n",
       "      <td>0.007002</td>\n",
       "      <td>-0.014082</td>\n",
       "      <td>-0.009283</td>\n",
       "      <td>-0.003032</td>\n",
       "      <td>-0.015690</td>\n",
       "      <td>-0.002476</td>\n",
       "      <td>0.009485</td>\n",
       "      <td>0.013930</td>\n",
       "      <td>-0.016383</td>\n",
       "      <td>0.016043</td>\n",
       "      <td>0.003408</td>\n",
       "      <td>-0.009370</td>\n",
       "      <td>0.012278</td>\n",
       "      <td>0.004710</td>\n",
       "      <td>0.017376</td>\n",
       "      <td>0.015070</td>\n",
       "      <td>-0.004606</td>\n",
       "      <td>0.009077</td>\n",
       "      <td>0.021997</td>\n",
       "      <td>-0.020869</td>\n",
       "      <td>-0.009772</td>\n",
       "      <td>-0.008514</td>\n",
       "      <td>-0.004545</td>\n",
       "      <td>0.019639</td>\n",
       "      <td>0.010824</td>\n",
       "      <td>-0.012849</td>\n",
       "      <td>-0.011415</td>\n",
       "      <td>0.002991</td>\n",
       "      <td>-0.010763</td>\n",
       "      <td>-0.015348</td>\n",
       "      <td>-0.030125</td>\n",
       "      <td>-0.004401</td>\n",
       "      <td>-0.026870</td>\n",
       "      <td>0.021142</td>\n",
       "      <td>-0.011081</td>\n",
       "      <td>-0.005970</td>\n",
       "      <td>-0.020063</td>\n",
       "      <td>0.008371</td>\n",
       "      <td>0.017486</td>\n",
       "      <td>-0.016539</td>\n",
       "      <td>0.015583</td>\n",
       "      <td>0.017362</td>\n",
       "      <td>0.017482</td>\n",
       "      <td>-0.013634</td>\n",
       "      <td>0.009486</td>\n",
       "      <td>0.007944</td>\n",
       "      <td>-0.005911</td>\n",
       "      <td>-0.010120</td>\n",
       "      <td>0.017313</td>\n",
       "      <td>0.003824</td>\n",
       "      <td>0.016970</td>\n",
       "      <td>-0.002640</td>\n",
       "      <td>0.005406</td>\n",
       "      <td>-0.001158</td>\n",
       "      <td>0.007805</td>\n",
       "      <td>-0.007749</td>\n",
       "      <td>-0.001430</td>\n",
       "      <td>0.001831</td>\n",
       "      <td>0.009916</td>\n",
       "      <td>-0.002302</td>\n",
       "      <td>-0.001810</td>\n",
       "      <td>0.003421</td>\n",
       "      <td>-0.000026</td>\n",
       "      <td>0.007665</td>\n",
       "      <td>0.006362</td>\n",
       "      <td>-0.000269</td>\n",
       "      <td>0.013439</td>\n",
       "      <td>-0.009226</td>\n",
       "      <td>0.018706</td>\n",
       "      <td>0.009456</td>\n",
       "      <td>0.029043</td>\n",
       "      <td>0.005632</td>\n",
       "      <td>0.010316</td>\n",
       "      <td>0.015829</td>\n",
       "      <td>0.017358</td>\n",
       "      <td>0.013094</td>\n",
       "      <td>0.011203</td>\n",
       "      <td>0.002598</td>\n",
       "      <td>-0.001974</td>\n",
       "      <td>-0.003581</td>\n",
       "      <td>-0.003643</td>\n",
       "      <td>-0.013625</td>\n",
       "      <td>0.016447</td>\n",
       "      <td>0.006203</td>\n",
       "      <td>0.011155</td>\n",
       "      <td>0.011566</td>\n",
       "      <td>0.001913</td>\n",
       "      <td>0.002399</td>\n",
       "      <td>0.010810</td>\n",
       "      <td>-0.003206</td>\n",
       "      <td>0.016123</td>\n",
       "      <td>0.013276</td>\n",
       "      <td>0.015529</td>\n",
       "      <td>-0.027641</td>\n",
       "      <td>0.019060</td>\n",
       "      <td>-0.011804</td>\n",
       "      <td>0.002870</td>\n",
       "      <td>-0.005589</td>\n",
       "      <td>-0.004730</td>\n",
       "      <td>-0.021442</td>\n",
       "      <td>-0.012115</td>\n",
       "      <td>-0.022686</td>\n",
       "      <td>-0.013018</td>\n",
       "      <td>-0.004547</td>\n",
       "      <td>0.006958</td>\n",
       "      <td>0.008048</td>\n",
       "      <td>-0.006868</td>\n",
       "      <td>0.010789</td>\n",
       "      <td>-0.007893</td>\n",
       "      <td>-0.001248</td>\n",
       "      <td>0.003799</td>\n",
       "      <td>-0.002381</td>\n",
       "      <td>-0.006109</td>\n",
       "      <td>0.003281</td>\n",
       "      <td>-0.005142</td>\n",
       "      <td>0.000199</td>\n",
       "      <td>-0.000959</td>\n",
       "      <td>-0.021478</td>\n",
       "      <td>0.004442</td>\n",
       "      <td>0.002498</td>\n",
       "      <td>0.018469</td>\n",
       "      <td>-0.004143</td>\n",
       "      <td>0.012593</td>\n",
       "      <td>-0.008374</td>\n",
       "      <td>-0.002815</td>\n",
       "      <td>0.002150</td>\n",
       "      <td>-0.005808</td>\n",
       "      <td>0.013172</td>\n",
       "      <td>0.004673</td>\n",
       "      <td>-0.023360</td>\n",
       "      <td>-0.012518</td>\n",
       "      <td>-0.006254</td>\n",
       "      <td>0.014935</td>\n",
       "      <td>-0.020285</td>\n",
       "      <td>-0.000212</td>\n",
       "      <td>7.0</td>\n",
       "      <td>63</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>3733 rows × 1282 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "             0         1         2         3         4         5         6  \\\n",
       "0     0.002264 -0.002781  0.002993  0.000917 -0.002048 -0.000943 -0.001373   \n",
       "1     0.002264 -0.002781  0.002993  0.000917 -0.002048 -0.000943 -0.001373   \n",
       "2     0.002264 -0.002781  0.002993  0.000917 -0.002048 -0.000943 -0.001373   \n",
       "3     0.002264 -0.002781  0.002993  0.000917 -0.002048 -0.000943 -0.001373   \n",
       "4     0.003853 -0.001638  0.002186  0.000431 -0.000128 -0.004285  0.000982   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.006661  0.008035 -0.009155 -0.002379  0.012057  0.001170 -0.010383   \n",
       "3729 -0.002724  0.007787 -0.007066 -0.002400  0.009299  0.002487 -0.013997   \n",
       "3730 -0.013817  0.029486  0.004163 -0.006857 -0.003146 -0.006858 -0.005760   \n",
       "3731 -0.007250  0.010681  0.001937  0.001830 -0.000256  0.003161 -0.014018   \n",
       "3732 -0.016595  0.008654  0.009148 -0.005493 -0.001894  0.002628 -0.014169   \n",
       "\n",
       "             7         8         9        10        11        12        13  \\\n",
       "0     0.003532 -0.001310  0.000956  0.000494  0.001978  0.002956 -0.001324   \n",
       "1     0.003532 -0.001310  0.000956  0.000494  0.001978  0.002956 -0.001324   \n",
       "2     0.003532 -0.001310  0.000956  0.000494  0.001978  0.002956 -0.001324   \n",
       "3     0.003532 -0.001310  0.000956  0.000494  0.001978  0.002956 -0.001324   \n",
       "4     0.001414 -0.002309 -0.001756 -0.000616 -0.001022  0.004372  0.002630   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.014578 -0.000262 -0.001369 -0.000100 -0.003785  0.011649  0.010520   \n",
       "3729 -0.010191  0.002911 -0.002189  0.001210 -0.001323  0.014294  0.010910   \n",
       "3730 -0.020783 -0.013606 -0.005511  0.004536  0.002366 -0.011819  0.009227   \n",
       "3731 -0.017502 -0.000072 -0.000415  0.002674 -0.004436 -0.001075  0.008390   \n",
       "3732 -0.014779 -0.007168 -0.001789  0.006362  0.000314 -0.003315  0.006398   \n",
       "\n",
       "            14        15        16        17        18        19        20  \\\n",
       "0     0.000159 -0.004518  0.001749 -0.000429  0.000160 -0.002305 -0.001531   \n",
       "1     0.000159 -0.004518  0.001749 -0.000429  0.000160 -0.002305 -0.001531   \n",
       "2     0.000159 -0.004518  0.001749 -0.000429  0.000160 -0.002305 -0.001531   \n",
       "3     0.000159 -0.004518  0.001749 -0.000429  0.000160 -0.002305 -0.001531   \n",
       "4     0.001775 -0.004346  0.004295  0.001574  0.001650 -0.000780  0.004574   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002360  0.008861 -0.008410 -0.005508  0.004878  0.000146  0.000909   \n",
       "3729  0.000119  0.015777 -0.005181 -0.001773  0.003858  0.005053  0.004114   \n",
       "3730  0.000824 -0.009165  0.005680  0.002049 -0.004772  0.009497 -0.001135   \n",
       "3731  0.000579  0.000157  0.007658 -0.003908 -0.004524  0.007933  0.001242   \n",
       "3732 -0.006350 -0.007348  0.011564  0.001449 -0.002290  0.012800  0.000849   \n",
       "\n",
       "            21        22        23        24        25        26        27  \\\n",
       "0    -0.003535  0.000692  0.004050 -0.001401 -0.002957 -0.001412 -0.002671   \n",
       "1    -0.003535  0.000692  0.004050 -0.001401 -0.002957 -0.001412 -0.002671   \n",
       "2    -0.003535  0.000692  0.004050 -0.001401 -0.002957 -0.001412 -0.002671   \n",
       "3    -0.003535  0.000692  0.004050 -0.001401 -0.002957 -0.001412 -0.002671   \n",
       "4     0.000564 -0.000518 -0.000238 -0.004106 -0.001015 -0.002564 -0.000180   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.010197  0.005627 -0.003347 -0.008280  0.005344 -0.001989  0.010492   \n",
       "3729 -0.004690  0.004562  0.005725 -0.003837  0.004453  0.000589  0.011127   \n",
       "3730  0.002838 -0.005431  0.017724 -0.018711  0.004037 -0.002446  0.013329   \n",
       "3731  0.005038 -0.006273  0.007947 -0.004193 -0.001508  0.004787  0.006453   \n",
       "3732  0.013553 -0.019136  0.010726 -0.005807  0.005303  0.010414  0.016278   \n",
       "\n",
       "            28        29        30        31        32        33        34  \\\n",
       "0    -0.005783 -0.001800  0.000789  0.000644 -0.001406  0.002964  0.002923   \n",
       "1    -0.005783 -0.001800  0.000789  0.000644 -0.001406  0.002964  0.002923   \n",
       "2    -0.005783 -0.001800  0.000789  0.000644 -0.001406  0.002964  0.002923   \n",
       "3    -0.005783 -0.001800  0.000789  0.000644 -0.001406  0.002964  0.002923   \n",
       "4    -0.003691 -0.003195  0.003009 -0.002052  0.000583  0.002756  0.002906   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000308  0.002057 -0.004840 -0.008720  0.006413 -0.006073 -0.000787   \n",
       "3729  0.007825  0.008336 -0.007697 -0.012211  0.005751 -0.002159 -0.004701   \n",
       "3730  0.019957  0.002075 -0.008593 -0.031132  0.016551 -0.007283  0.000183   \n",
       "3731  0.010137  0.002791 -0.008499 -0.014031  0.011966 -0.005330  0.001109   \n",
       "3732  0.010089  0.001871 -0.013602 -0.027194  0.011761 -0.005217  0.000503   \n",
       "\n",
       "            35        36        37        38        39        40        41  \\\n",
       "0     0.000331 -0.001763  0.002445  0.000857  0.003599  0.002084  0.000838   \n",
       "1     0.000331 -0.001763  0.002445  0.000857  0.003599  0.002084  0.000838   \n",
       "2     0.000331 -0.001763  0.002445  0.000857  0.003599  0.002084  0.000838   \n",
       "3     0.000331 -0.001763  0.002445  0.000857  0.003599  0.002084  0.000838   \n",
       "4    -0.001518 -0.002610 -0.000182 -0.002618  0.005253  0.001746  0.002569   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000874  0.000702  0.001934 -0.003048  0.010093 -0.001104 -0.005891   \n",
       "3729  0.001710  0.003609  0.005504  0.000745  0.001493 -0.004776 -0.012364   \n",
       "3730  0.008546  0.015197  0.005375 -0.027229  0.001234  0.003968 -0.012269   \n",
       "3731  0.005351  0.002600  0.002456 -0.007334 -0.000589 -0.001588 -0.007897   \n",
       "3732  0.010388  0.009803  0.003312 -0.014931 -0.009624  0.001285 -0.018581   \n",
       "\n",
       "            42        43        44        45        46        47        48  \\\n",
       "0     0.001988  0.002288 -0.002258 -0.000847 -0.003599 -0.000986 -0.000161   \n",
       "1     0.001988  0.002288 -0.002258 -0.000847 -0.003599 -0.000986 -0.000161   \n",
       "2     0.001988  0.002288 -0.002258 -0.000847 -0.003599 -0.000986 -0.000161   \n",
       "3     0.001988  0.002288 -0.002258 -0.000847 -0.003599 -0.000986 -0.000161   \n",
       "4     0.004680 -0.002137 -0.002635  0.001493 -0.002922 -0.000322 -0.001423   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000750  0.000819  0.001298 -0.001453 -0.005122  0.008992  0.008380   \n",
       "3729 -0.001800  0.009390  0.007968  0.004202 -0.004562 -0.000726  0.002951   \n",
       "3730  0.004832  0.030357  0.006682  0.022506 -0.003107  0.004709  0.015330   \n",
       "3731 -0.003211  0.009203  0.009056  0.010293 -0.008282  0.003216  0.003554   \n",
       "3732 -0.010090  0.024998  0.006007  0.016121  0.004461  0.009184  0.012555   \n",
       "\n",
       "            49        50        51        52        53        54        55  \\\n",
       "0     0.000132  0.001182  0.000753 -0.000701 -0.003558  0.001556 -0.001667   \n",
       "1     0.000132  0.001182  0.000753 -0.000701 -0.003558  0.001556 -0.001667   \n",
       "2     0.000132  0.001182  0.000753 -0.000701 -0.003558  0.001556 -0.001667   \n",
       "3     0.000132  0.001182  0.000753 -0.000701 -0.003558  0.001556 -0.001667   \n",
       "4     0.005636 -0.001817 -0.001013 -0.003184 -0.002559  0.009711 -0.002469   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004086  0.001841 -0.007458 -0.000454  0.000247 -0.004169 -0.001864   \n",
       "3729 -0.004138  0.001296  0.000579 -0.000856  0.001809  0.000038 -0.005483   \n",
       "3730  0.011958 -0.012516  0.010450  0.010154 -0.001952 -0.009371  0.000979   \n",
       "3731  0.004690 -0.007954  0.012563 -0.000145 -0.003719 -0.004974 -0.002530   \n",
       "3732  0.002390 -0.019372  0.004416  0.010102 -0.003217 -0.003456  0.000066   \n",
       "\n",
       "            56        57        58        59        60        61        62  \\\n",
       "0     0.000404 -0.002945 -0.000815  0.000181 -0.001925 -0.000805 -0.000866   \n",
       "1     0.000404 -0.002945 -0.000815  0.000181 -0.001925 -0.000805 -0.000866   \n",
       "2     0.000404 -0.002945 -0.000815  0.000181 -0.001925 -0.000805 -0.000866   \n",
       "3     0.000404 -0.002945 -0.000815  0.000181 -0.001925 -0.000805 -0.000866   \n",
       "4    -0.000687 -0.004585 -0.002262 -0.001022 -0.001254  0.001460 -0.001986   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000842  0.004651 -0.004672 -0.000904 -0.015490  0.001277  0.000315   \n",
       "3729  0.003796 -0.000217 -0.001855  0.000621 -0.017781 -0.001356  0.000694   \n",
       "3730  0.001045 -0.018790  0.030410 -0.015791 -0.010844 -0.010366 -0.019603   \n",
       "3731 -0.003820 -0.006691  0.005638 -0.015904 -0.003484 -0.000806 -0.010431   \n",
       "3732 -0.002271 -0.012721  0.018290 -0.010729  0.001988  0.001770 -0.024568   \n",
       "\n",
       "            63        64        65        66        67        68        69  \\\n",
       "0     0.001052  0.002684 -0.001088  0.000095 -0.000506 -0.000254  0.002048   \n",
       "1     0.001052  0.002684 -0.001088  0.000095 -0.000506 -0.000254  0.002048   \n",
       "2     0.001052  0.002684 -0.001088  0.000095 -0.000506 -0.000254  0.002048   \n",
       "3     0.001052  0.002684 -0.001088  0.000095 -0.000506 -0.000254  0.002048   \n",
       "4     0.002875  0.000172  0.005543 -0.002761 -0.004694  0.001504  0.001256   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000880  0.000643 -0.000966  0.002334  0.002999  0.010536 -0.007842   \n",
       "3729  0.003654 -0.007425  0.000844  0.000635  0.008710  0.007147 -0.009407   \n",
       "3730  0.012453 -0.011735 -0.009174 -0.011356  0.002003  0.026720 -0.014379   \n",
       "3731  0.007221 -0.011856  0.000213 -0.000926  0.005853  0.011368 -0.005753   \n",
       "3732  0.010619 -0.014107  0.004676 -0.011958  0.001761  0.018364 -0.013275   \n",
       "\n",
       "            70        71        72        73        74        75        76  \\\n",
       "0    -0.000409  0.001096  0.002053 -0.000217  0.001507  0.001486 -0.001707   \n",
       "1    -0.000409  0.001096  0.002053 -0.000217  0.001507  0.001486 -0.001707   \n",
       "2    -0.000409  0.001096  0.002053 -0.000217  0.001507  0.001486 -0.001707   \n",
       "3    -0.000409  0.001096  0.002053 -0.000217  0.001507  0.001486 -0.001707   \n",
       "4    -0.002305 -0.000342  0.005839 -0.000132  0.002023  0.000065  0.002842   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001472 -0.001820  0.012176 -0.010065  0.003330  0.005807  0.001499   \n",
       "3729 -0.001366 -0.000456  0.010988 -0.008692  0.000296  0.003894  0.001344   \n",
       "3730 -0.004154 -0.005030  0.010091  0.004844 -0.016566 -0.018063  0.017815   \n",
       "3731 -0.006626  0.002051  0.006200 -0.000874 -0.006153 -0.009126  0.010836   \n",
       "3732 -0.006591 -0.011522  0.000835  0.005047 -0.011516 -0.011753  0.016469   \n",
       "\n",
       "            77        78        79        80        81        82        83  \\\n",
       "0    -0.004411 -0.000653 -0.004783 -0.001617  0.002622 -0.000836  0.000663   \n",
       "1    -0.004411 -0.000653 -0.004783 -0.001617  0.002622 -0.000836  0.000663   \n",
       "2    -0.004411 -0.000653 -0.004783 -0.001617  0.002622 -0.000836  0.000663   \n",
       "3    -0.004411 -0.000653 -0.004783 -0.001617  0.002622 -0.000836  0.000663   \n",
       "4     0.000172 -0.000641 -0.003277  0.002402  0.001204  0.001047  0.004657   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.004587  0.013865 -0.005267 -0.001168 -0.002768  0.011779 -0.004908   \n",
       "3729 -0.007581  0.012047 -0.010191 -0.003874  0.000614  0.013449 -0.006154   \n",
       "3730 -0.001962  0.023236 -0.016707 -0.010219  0.018616  0.005775  0.001706   \n",
       "3731 -0.004327  0.007637 -0.005355 -0.003018  0.012580  0.006697 -0.002883   \n",
       "3732 -0.007339  0.012844 -0.005266 -0.011977  0.017150  0.002303 -0.006094   \n",
       "\n",
       "            84        85        86        87        88        89        90  \\\n",
       "0     0.002321  0.000604 -0.001914 -0.001732 -0.001250  0.003528 -0.002242   \n",
       "1     0.002321  0.000604 -0.001914 -0.001732 -0.001250  0.003528 -0.002242   \n",
       "2     0.002321  0.000604 -0.001914 -0.001732 -0.001250  0.003528 -0.002242   \n",
       "3     0.002321  0.000604 -0.001914 -0.001732 -0.001250  0.003528 -0.002242   \n",
       "4     0.004583  0.003967 -0.001267 -0.002492 -0.000786  0.000506  0.004314   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002949 -0.001528  0.006520  0.003971 -0.014087 -0.001978 -0.002435   \n",
       "3729  0.004701 -0.009012  0.000899  0.002502 -0.012761 -0.001295 -0.001363   \n",
       "3730  0.003636 -0.013513 -0.006076 -0.015916 -0.015545 -0.043431 -0.019811   \n",
       "3731  0.002679 -0.007311 -0.010468 -0.006407 -0.007886 -0.020670 -0.012947   \n",
       "3732 -0.000440 -0.019107 -0.002151  0.002496 -0.013628 -0.034850 -0.011237   \n",
       "\n",
       "            91        92        93        94        95        96        97  \\\n",
       "0    -0.000436  0.003464 -0.003407  0.001447 -0.001400 -0.000898 -0.003024   \n",
       "1    -0.000436  0.003464 -0.003407  0.001447 -0.001400 -0.000898 -0.003024   \n",
       "2    -0.000436  0.003464 -0.003407  0.001447 -0.001400 -0.000898 -0.003024   \n",
       "3    -0.000436  0.003464 -0.003407  0.001447 -0.001400 -0.000898 -0.003024   \n",
       "4     0.007555  0.004109 -0.004471 -0.000172 -0.004557  0.004416 -0.003030   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.007682  0.001798  0.005424  0.000785  0.002474 -0.004325  0.010047   \n",
       "3729  0.011653  0.003232  0.000523  0.001914 -0.004107 -0.006095  0.006232   \n",
       "3730  0.017508  0.004577 -0.008067 -0.007936  0.005138 -0.023033  0.019174   \n",
       "3731  0.011579  0.002128 -0.003013 -0.000399 -0.001320 -0.008404  0.005015   \n",
       "3732  0.014332  0.008100 -0.008833 -0.001671  0.001229 -0.008469  0.014049   \n",
       "\n",
       "            98        99       100       101       102       103       104  \\\n",
       "0     0.000172 -0.001813  0.000429  0.000182  0.001863 -0.001118 -0.000239   \n",
       "1     0.000172 -0.001813  0.000429  0.000182  0.001863 -0.001118 -0.000239   \n",
       "2     0.000172 -0.001813  0.000429  0.000182  0.001863 -0.001118 -0.000239   \n",
       "3     0.000172 -0.001813  0.000429  0.000182  0.001863 -0.001118 -0.000239   \n",
       "4     0.006550 -0.000294  0.002094  0.000139 -0.001935 -0.002004  0.000801   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001245  0.000782  0.001380 -0.007101  0.004379 -0.016788  0.003815   \n",
       "3729  0.005831 -0.003227 -0.003540 -0.005055  0.000378 -0.014963  0.007589   \n",
       "3730  0.014443  0.004330 -0.024569  0.003846 -0.005940  0.009754 -0.002102   \n",
       "3731  0.007666 -0.000590 -0.014397  0.005685  0.003029 -0.000131 -0.000830   \n",
       "3732  0.019063 -0.009205 -0.017206  0.010377 -0.006699  0.010292  0.002353   \n",
       "\n",
       "           105       106       107       108       109       110       111  \\\n",
       "0     0.000214 -0.000794  0.000371 -0.004499 -0.001445 -0.000384  0.000988   \n",
       "1     0.000214 -0.000794  0.000371 -0.004499 -0.001445 -0.000384  0.000988   \n",
       "2     0.000214 -0.000794  0.000371 -0.004499 -0.001445 -0.000384  0.000988   \n",
       "3     0.000214 -0.000794  0.000371 -0.004499 -0.001445 -0.000384  0.000988   \n",
       "4    -0.001115  0.000874  0.001151 -0.005034 -0.004070 -0.000181  0.001080   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.010296 -0.003348  0.000314 -0.001236  0.002431  0.008731  0.007047   \n",
       "3729 -0.010509 -0.002817 -0.000428 -0.000733 -0.000088  0.013444  0.004726   \n",
       "3730  0.009882  0.001693 -0.030379  0.010157 -0.000368  0.007206 -0.006936   \n",
       "3731  0.002798 -0.000288 -0.018083 -0.000779 -0.002497  0.001682  0.004520   \n",
       "3732  0.003203  0.001729 -0.031671 -0.000166  0.004591  0.013195 -0.001430   \n",
       "\n",
       "           112       113       114       115       116       117       118  \\\n",
       "0    -0.003692 -0.002095  0.003049  0.000173 -0.000566 -0.003763 -0.000194   \n",
       "1    -0.003692 -0.002095  0.003049  0.000173 -0.000566 -0.003763 -0.000194   \n",
       "2    -0.003692 -0.002095  0.003049  0.000173 -0.000566 -0.003763 -0.000194   \n",
       "3    -0.003692 -0.002095  0.003049  0.000173 -0.000566 -0.003763 -0.000194   \n",
       "4    -0.002773 -0.002241  0.000619  0.000899  0.003798 -0.006009 -0.001476   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003466 -0.000396  0.002814  0.001742 -0.001981  0.004173  0.006286   \n",
       "3729 -0.000793 -0.000495 -0.002788  0.003193 -0.003190  0.004836  0.010157   \n",
       "3730 -0.026398 -0.010783 -0.000808 -0.008741 -0.003591  0.006397  0.013311   \n",
       "3731 -0.012443 -0.004066 -0.008998 -0.002739  0.000396  0.005075  0.004880   \n",
       "3732 -0.018670 -0.003304 -0.001970 -0.014481  0.010218  0.012360  0.003092   \n",
       "\n",
       "           119       120       121       122       123       124       125  \\\n",
       "0    -0.001850  0.000367  0.000450  0.004017  0.001443  0.001012 -0.005538   \n",
       "1    -0.001850  0.000367  0.000450  0.004017  0.001443  0.001012 -0.005538   \n",
       "2    -0.001850  0.000367  0.000450  0.004017  0.001443  0.001012 -0.005538   \n",
       "3    -0.001850  0.000367  0.000450  0.004017  0.001443  0.001012 -0.005538   \n",
       "4    -0.003195  0.000434  0.000206  0.005530  0.002120  0.001604 -0.005251   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006267  0.002057  0.006258  0.000590 -0.000886  0.000743 -0.001886   \n",
       "3729  0.003471  0.003176 -0.001430  0.002779  0.000927  0.003559  0.002018   \n",
       "3730  0.020450  0.021508 -0.003182  0.016967  0.004793  0.018619  0.003864   \n",
       "3731  0.007304  0.011346 -0.003428  0.004378  0.002899  0.007395  0.001198   \n",
       "3732  0.022095  0.013556 -0.003933  0.004627 -0.001145  0.012032  0.002315   \n",
       "\n",
       "           126       127       128       129       130       131       132  \\\n",
       "0     0.000612  0.003135 -0.003770  0.002729  0.004400 -0.003667 -0.002163   \n",
       "1     0.000612  0.003135 -0.003770  0.002729  0.004400 -0.003667 -0.002163   \n",
       "2     0.000612  0.003135 -0.003770  0.002729  0.004400 -0.003667 -0.002163   \n",
       "3     0.000612  0.003135 -0.003770  0.002729  0.004400 -0.003667 -0.002163   \n",
       "4    -0.002049  0.000679 -0.000616  0.003415  0.001761 -0.008393 -0.005606   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.010072 -0.008955  0.004005 -0.006064  0.001202 -0.011365  0.007115   \n",
       "3729  0.010563 -0.009158  0.002161  0.003750  0.000256 -0.000124  0.008097   \n",
       "3730 -0.004481  0.007448 -0.010699 -0.003103  0.004254 -0.007405  0.005357   \n",
       "3731 -0.005339 -0.000887 -0.006405 -0.000234  0.000939 -0.004984  0.009300   \n",
       "3732 -0.003432  0.016435 -0.006083 -0.001418  0.010155 -0.000679  0.006938   \n",
       "\n",
       "           133       134       135       136       137       138       139  \\\n",
       "0    -0.004647  0.002732  0.000223 -0.002755 -0.001669 -0.003186 -0.000577   \n",
       "1    -0.004647  0.002732  0.000223 -0.002755 -0.001669 -0.003186 -0.000577   \n",
       "2    -0.004647  0.002732  0.000223 -0.002755 -0.001669 -0.003186 -0.000577   \n",
       "3    -0.004647  0.002732  0.000223 -0.002755 -0.001669 -0.003186 -0.000577   \n",
       "4    -0.004140 -0.002662  0.002551 -0.000123  0.000246 -0.003948 -0.000277   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006979 -0.002902  0.001239  0.005093  0.002054  0.004021 -0.000939   \n",
       "3729  0.013262 -0.012737  0.003750  0.006103  0.003310  0.008989 -0.013596   \n",
       "3730  0.009162 -0.010082  0.000335  0.018767  0.010207  0.004382 -0.030507   \n",
       "3731  0.006018 -0.012792  0.000905  0.003390  0.001436  0.000531 -0.013102   \n",
       "3732  0.009583 -0.013079 -0.005077  0.012050  0.008688  0.005268 -0.020090   \n",
       "\n",
       "           140       141       142       143       144       145       146  \\\n",
       "0    -0.000050 -0.001026  0.000400 -0.002904 -0.002644  0.000031  0.000291   \n",
       "1    -0.000050 -0.001026  0.000400 -0.002904 -0.002644  0.000031  0.000291   \n",
       "2    -0.000050 -0.001026  0.000400 -0.002904 -0.002644  0.000031  0.000291   \n",
       "3    -0.000050 -0.001026  0.000400 -0.002904 -0.002644  0.000031  0.000291   \n",
       "4     0.008579 -0.003803 -0.002374 -0.003799 -0.001111  0.001898 -0.006589   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002941  0.001077 -0.002809  0.007325 -0.002161 -0.002183 -0.001572   \n",
       "3729 -0.000447  0.004129  0.001855  0.004156  0.001040  0.003033 -0.000665   \n",
       "3730  0.000174  0.020003  0.016618  0.005997  0.013674  0.012354 -0.007659   \n",
       "3731 -0.004529  0.012801  0.009320  0.002086  0.000250  0.005904 -0.001679   \n",
       "3732 -0.000855  0.020139  0.014240  0.007505  0.003426 -0.000142 -0.004549   \n",
       "\n",
       "           147       148       149       150       151       152       153  \\\n",
       "0     0.000299 -0.001210 -0.006243 -0.000687  0.000380  0.000338  0.001924   \n",
       "1     0.000299 -0.001210 -0.006243 -0.000687  0.000380  0.000338  0.001924   \n",
       "2     0.000299 -0.001210 -0.006243 -0.000687  0.000380  0.000338  0.001924   \n",
       "3     0.000299 -0.001210 -0.006243 -0.000687  0.000380  0.000338  0.001924   \n",
       "4     0.004565 -0.002189  0.000803  0.000402 -0.001357  0.001973 -0.000617   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005658  0.014356  0.015845  0.001005 -0.020120  0.003715  0.008217   \n",
       "3729  0.002755  0.013948  0.019850  0.001451 -0.010431 -0.003467  0.006878   \n",
       "3730 -0.005620  0.027860  0.009417  0.000160 -0.017519  0.008741  0.004206   \n",
       "3731  0.003186  0.017235  0.011951  0.007042 -0.011712 -0.001991  0.005952   \n",
       "3732 -0.007838  0.014188  0.003207  0.008977 -0.002974 -0.005526  0.003672   \n",
       "\n",
       "           154       155       156       157       158       159       160  \\\n",
       "0     0.003758 -0.001165  0.002976 -0.002542  0.002483  0.003616  0.003965   \n",
       "1     0.003758 -0.001165  0.002976 -0.002542  0.002483  0.003616  0.003965   \n",
       "2     0.003758 -0.001165  0.002976 -0.002542  0.002483  0.003616  0.003965   \n",
       "3     0.003758 -0.001165  0.002976 -0.002542  0.002483  0.003616  0.003965   \n",
       "4     0.001813 -0.000866  0.000793 -0.001070  0.007350  0.001474  0.000579   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005294  0.000538 -0.002771 -0.010204 -0.001250  0.000537 -0.008371   \n",
       "3729  0.005111 -0.001983  0.000022 -0.010051  0.001680  0.003492 -0.008625   \n",
       "3730  0.017736  0.004551 -0.031189 -0.008378  0.013416  0.017877 -0.015795   \n",
       "3731  0.009968 -0.004089 -0.010154 -0.006181  0.009170  0.004156 -0.012418   \n",
       "3732  0.009672 -0.010718 -0.017338 -0.001117  0.015449  0.005066 -0.019222   \n",
       "\n",
       "           161       162       163       164       165       166       167  \\\n",
       "0     0.002296 -0.002932 -0.001902 -0.001479 -0.002883  0.001939 -0.000959   \n",
       "1     0.002296 -0.002932 -0.001902 -0.001479 -0.002883  0.001939 -0.000959   \n",
       "2     0.002296 -0.002932 -0.001902 -0.001479 -0.002883  0.001939 -0.000959   \n",
       "3     0.002296 -0.002932 -0.001902 -0.001479 -0.002883  0.001939 -0.000959   \n",
       "4    -0.000975 -0.001479  0.000114 -0.004684 -0.001033  0.001320 -0.001499   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003366  0.006575 -0.011439 -0.000367 -0.000205 -0.004282 -0.010399   \n",
       "3729  0.002655  0.008986 -0.009102  0.004546 -0.002175  0.001419 -0.006023   \n",
       "3730  0.006893  0.002410 -0.008935  0.018810  0.003437 -0.011405  0.002271   \n",
       "3731  0.006307 -0.001439 -0.008441  0.005196  0.003037 -0.000832 -0.002481   \n",
       "3732  0.005699 -0.002498 -0.012049  0.020929  0.007751 -0.003583 -0.003159   \n",
       "\n",
       "           168       169       170       171       172       173       174  \\\n",
       "0     0.005660  0.003752  0.002197 -0.004241 -0.000442  0.001944 -0.001895   \n",
       "1     0.005660  0.003752  0.002197 -0.004241 -0.000442  0.001944 -0.001895   \n",
       "2     0.005660  0.003752  0.002197 -0.004241 -0.000442  0.001944 -0.001895   \n",
       "3     0.005660  0.003752  0.002197 -0.004241 -0.000442  0.001944 -0.001895   \n",
       "4     0.009720  0.009095 -0.000479 -0.002496  0.005451 -0.002381 -0.006568   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.012962 -0.003479 -0.002665 -0.006844 -0.002174  0.003723 -0.000374   \n",
       "3729 -0.013813 -0.008731 -0.002750 -0.003578  0.002801  0.004397  0.001074   \n",
       "3730 -0.011639 -0.003768  0.001463  0.022149  0.007753  0.011312  0.016575   \n",
       "3731 -0.008815  0.001964 -0.001764  0.007164  0.005435  0.009361  0.002293   \n",
       "3732 -0.010841 -0.001117 -0.002337  0.018327  0.007435  0.004053  0.011110   \n",
       "\n",
       "           175       176       177       178       179       180       181  \\\n",
       "0     0.001196  0.001153 -0.001157 -0.000928 -0.000634 -0.001801 -0.000689   \n",
       "1     0.001196  0.001153 -0.001157 -0.000928 -0.000634 -0.001801 -0.000689   \n",
       "2     0.001196  0.001153 -0.001157 -0.000928 -0.000634 -0.001801 -0.000689   \n",
       "3     0.001196  0.001153 -0.001157 -0.000928 -0.000634 -0.001801 -0.000689   \n",
       "4     0.000818 -0.000777 -0.001941  0.001694 -0.001048 -0.001094 -0.002372   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001962 -0.002583  0.008642  0.009354  0.004081  0.009041  0.001104   \n",
       "3729 -0.004851 -0.004807  0.014170 -0.000321  0.001245  0.005663 -0.002102   \n",
       "3730  0.001292 -0.004871  0.027889 -0.004440  0.001244  0.030290  0.006598   \n",
       "3731 -0.006171 -0.000127  0.013808 -0.006503 -0.001582  0.014487  0.002667   \n",
       "3732  0.000133 -0.004431  0.019085  0.000372 -0.004825  0.018926  0.005251   \n",
       "\n",
       "           182       183       184       185       186       187       188  \\\n",
       "0    -0.000311  0.001668  0.005369  0.000414 -0.003066 -0.001738 -0.000894   \n",
       "1    -0.000311  0.001668  0.005369  0.000414 -0.003066 -0.001738 -0.000894   \n",
       "2    -0.000311  0.001668  0.005369  0.000414 -0.003066 -0.001738 -0.000894   \n",
       "3    -0.000311  0.001668  0.005369  0.000414 -0.003066 -0.001738 -0.000894   \n",
       "4     0.003461  0.002125  0.005880 -0.001812 -0.004756 -0.002478 -0.001727   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.019568  0.000346 -0.005160 -0.003144 -0.003889  0.006800 -0.000453   \n",
       "3729  0.022356 -0.005086 -0.009174 -0.010805 -0.002388  0.003683 -0.003892   \n",
       "3730  0.021688 -0.015311 -0.033538 -0.023275 -0.005647 -0.005842 -0.014474   \n",
       "3731  0.008659 -0.010944 -0.012319 -0.010742 -0.003507 -0.008380 -0.011294   \n",
       "3732  0.010804 -0.011814 -0.025145 -0.023071 -0.002068 -0.013540 -0.017623   \n",
       "\n",
       "           189       190       191       192       193       194       195  \\\n",
       "0     0.001454  0.000284  0.001212  0.000961  0.003414  0.001085  0.001937   \n",
       "1     0.001454  0.000284  0.001212  0.000961  0.003414  0.001085  0.001937   \n",
       "2     0.001454  0.000284  0.001212  0.000961  0.003414  0.001085  0.001937   \n",
       "3     0.001454  0.000284  0.001212  0.000961  0.003414  0.001085  0.001937   \n",
       "4     0.000934 -0.002096  0.005320  0.005873  0.001318  0.006239  0.004023   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.007395  0.007177 -0.003426 -0.005095 -0.001730 -0.009898  0.008350   \n",
       "3729 -0.004609  0.009088 -0.002382 -0.001478 -0.001064 -0.015240  0.005695   \n",
       "3730 -0.023420  0.012506 -0.001489 -0.013685  0.002451 -0.016600 -0.004520   \n",
       "3731 -0.009130  0.008082  0.004172 -0.011418  0.003180 -0.008517  0.005515   \n",
       "3732 -0.011473  0.006998  0.001307 -0.010179  0.000029 -0.012880  0.007577   \n",
       "\n",
       "           196       197       198       199       200       201       202  \\\n",
       "0     0.002022  0.000744 -0.001984 -0.002250 -0.000303  0.001081  0.002969   \n",
       "1     0.002022  0.000744 -0.001984 -0.002250 -0.000303  0.001081  0.002969   \n",
       "2     0.002022  0.000744 -0.001984 -0.002250 -0.000303  0.001081  0.002969   \n",
       "3     0.002022  0.000744 -0.001984 -0.002250 -0.000303  0.001081  0.002969   \n",
       "4     0.002781  0.002124  0.001255 -0.000090 -0.001551  0.004727 -0.001337   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001012 -0.000225  0.000610  0.009274 -0.013163  0.003724 -0.000954   \n",
       "3729 -0.002427  0.006492  0.001052  0.014906 -0.011286  0.001322  0.005292   \n",
       "3730 -0.013680  0.008426  0.015952  0.028872 -0.037229 -0.015976  0.003183   \n",
       "3731 -0.004291 -0.000111  0.008113  0.020709 -0.018188 -0.009293  0.001329   \n",
       "3732 -0.015883  0.008198  0.017956  0.024764 -0.020925 -0.017845  0.003839   \n",
       "\n",
       "           203       204       205       206       207       208       209  \\\n",
       "0    -0.002493 -0.002189 -0.000669  0.001176  0.000803 -0.001307  0.001025   \n",
       "1    -0.002493 -0.002189 -0.000669  0.001176  0.000803 -0.001307  0.001025   \n",
       "2    -0.002493 -0.002189 -0.000669  0.001176  0.000803 -0.001307  0.001025   \n",
       "3    -0.002493 -0.002189 -0.000669  0.001176  0.000803 -0.001307  0.001025   \n",
       "4    -0.003990 -0.001096  0.004467 -0.001238 -0.001964 -0.003978  0.001335   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001176 -0.007818  0.006224 -0.000388 -0.004777  0.001134  0.000671   \n",
       "3729  0.005158 -0.015527  0.010278  0.000852 -0.001418  0.002890  0.000876   \n",
       "3730 -0.012937 -0.020843  0.008284 -0.005596 -0.019925 -0.006461 -0.002456   \n",
       "3731 -0.005942 -0.009831  0.003341 -0.005842 -0.008502  0.004439 -0.002149   \n",
       "3732 -0.001957 -0.014348  0.009890 -0.014753 -0.012890 -0.004232 -0.001432   \n",
       "\n",
       "           210       211       212       213       214       215       216  \\\n",
       "0    -0.001513  0.000337  0.003410  0.000500  0.004680  0.002407  0.002494   \n",
       "1    -0.001513  0.000337  0.003410  0.000500  0.004680  0.002407  0.002494   \n",
       "2    -0.001513  0.000337  0.003410  0.000500  0.004680  0.002407  0.002494   \n",
       "3    -0.001513  0.000337  0.003410  0.000500  0.004680  0.002407  0.002494   \n",
       "4    -0.005609  0.001872  0.003155  0.001036  0.002717  0.003748  0.004367   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.010745  0.007090  0.007263 -0.001793  0.000294 -0.009408 -0.000706   \n",
       "3729  0.010951  0.012272  0.007803 -0.000186  0.001982 -0.006324 -0.012305   \n",
       "3730 -0.004706  0.005286  0.001027 -0.012596  0.010458  0.024066 -0.014056   \n",
       "3731 -0.005633  0.008586  0.006586 -0.005536  0.002291  0.007925 -0.012913   \n",
       "3732 -0.000821  0.009795  0.002814 -0.013248 -0.000909  0.006473 -0.016481   \n",
       "\n",
       "           217       218       219       220       221       222       223  \\\n",
       "0    -0.002360  0.001776  0.001366 -0.001027  0.001949 -0.002215 -0.001377   \n",
       "1    -0.002360  0.001776  0.001366 -0.001027  0.001949 -0.002215 -0.001377   \n",
       "2    -0.002360  0.001776  0.001366 -0.001027  0.001949 -0.002215 -0.001377   \n",
       "3    -0.002360  0.001776  0.001366 -0.001027  0.001949 -0.002215 -0.001377   \n",
       "4    -0.000375  0.006562 -0.002012 -0.003209  0.000956  0.002024 -0.004570   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000835  0.013093 -0.000602  0.003235 -0.002165 -0.000303  0.006226   \n",
       "3729  0.006880  0.011390  0.006979  0.006900 -0.002351 -0.004623  0.003284   \n",
       "3730  0.009543  0.015331  0.027695 -0.002671 -0.000830 -0.027700 -0.006220   \n",
       "3731  0.007025  0.010065  0.010313  0.001583  0.006456 -0.011551  0.003760   \n",
       "3732  0.004541  0.009552  0.019166  0.000422 -0.007727 -0.022280 -0.001256   \n",
       "\n",
       "           224       225       226       227       228       229       230  \\\n",
       "0    -0.001671 -0.000102 -0.000053  0.001773 -0.000605  0.003062 -0.002969   \n",
       "1    -0.001671 -0.000102 -0.000053  0.001773 -0.000605  0.003062 -0.002969   \n",
       "2    -0.001671 -0.000102 -0.000053  0.001773 -0.000605  0.003062 -0.002969   \n",
       "3    -0.001671 -0.000102 -0.000053  0.001773 -0.000605  0.003062 -0.002969   \n",
       "4    -0.002332  0.001395 -0.006333 -0.000461 -0.000622  0.001335 -0.003008   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.007822  0.009467 -0.006166 -0.010602  0.002417 -0.007640  0.001239   \n",
       "3729 -0.008359  0.002011 -0.010878 -0.019627 -0.003500 -0.006713  0.004848   \n",
       "3730 -0.016267  0.004343 -0.038930 -0.048439  0.002198  0.005094  0.008482   \n",
       "3731 -0.004879  0.002874 -0.017122 -0.018418 -0.003059 -0.000787 -0.000084   \n",
       "3732 -0.007679 -0.008628 -0.017947 -0.037143  0.002134  0.002289 -0.000842   \n",
       "\n",
       "           231       232       233       234       235       236       237  \\\n",
       "0     0.001387 -0.002893  0.004608 -0.009759 -0.000467 -0.001026 -0.002025   \n",
       "1     0.001387 -0.002893  0.004608 -0.009759 -0.000467 -0.001026 -0.002025   \n",
       "2     0.001387 -0.002893  0.004608 -0.009759 -0.000467 -0.001026 -0.002025   \n",
       "3     0.001387 -0.002893  0.004608 -0.009759 -0.000467 -0.001026 -0.002025   \n",
       "4     0.003822 -0.002796  0.007153  0.004183 -0.001526 -0.000269 -0.002673   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.011710  0.001674 -0.009277  0.018129 -0.000277  0.002837  0.010907   \n",
       "3729  0.008127 -0.006495 -0.005012 -0.007227  0.000678 -0.003699  0.007458   \n",
       "3730  0.026688 -0.000298 -0.012697 -0.057924 -0.002096 -0.006134 -0.006936   \n",
       "3731  0.008450 -0.003417 -0.000330  0.001458 -0.006649 -0.002847  0.005471   \n",
       "3732  0.005959 -0.003979 -0.004614 -0.025517 -0.007473  0.003903 -0.001601   \n",
       "\n",
       "           238       239       240       241       242       243       244  \\\n",
       "0     0.001440 -0.002747  0.002088 -0.001724 -0.002838 -0.002127  0.003677   \n",
       "1     0.001440 -0.002747  0.002088 -0.001724 -0.002838 -0.002127  0.003677   \n",
       "2     0.001440 -0.002747  0.002088 -0.001724 -0.002838 -0.002127  0.003677   \n",
       "3     0.001440 -0.002747  0.002088 -0.001724 -0.002838 -0.002127  0.003677   \n",
       "4    -0.000539 -0.000320  0.001280  0.002303  0.000291 -0.000373 -0.000196   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000019 -0.007891 -0.000513 -0.005164 -0.009073  0.006254 -0.004111   \n",
       "3729 -0.002257 -0.009661  0.000483 -0.002083 -0.014029  0.006224  0.001299   \n",
       "3730 -0.004946 -0.036442 -0.008732 -0.029264  0.001365  0.012135 -0.000512   \n",
       "3731 -0.002508 -0.021043 -0.003242 -0.010175 -0.005861  0.005688 -0.000224   \n",
       "3732 -0.007581 -0.025185 -0.004831 -0.020322  0.001702  0.010883  0.005525   \n",
       "\n",
       "           245       246       247       248       249       250       251  \\\n",
       "0     0.002016  0.001546 -0.001741  0.001510 -0.001113  0.001662 -0.000501   \n",
       "1     0.002016  0.001546 -0.001741  0.001510 -0.001113  0.001662 -0.000501   \n",
       "2     0.002016  0.001546 -0.001741  0.001510 -0.001113  0.001662 -0.000501   \n",
       "3     0.002016  0.001546 -0.001741  0.001510 -0.001113  0.001662 -0.000501   \n",
       "4     0.004313  0.000826 -0.000952 -0.003979 -0.004870 -0.001522  0.001179   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001554 -0.004333  0.004080 -0.000377 -0.003770 -0.008022  0.001184   \n",
       "3729  0.010819 -0.005987  0.004967 -0.001749 -0.000042 -0.001895 -0.001494   \n",
       "3730  0.025843  0.006282  0.012127  0.005752  0.005255  0.011738  0.008681   \n",
       "3731  0.005582 -0.006129  0.005690  0.000106  0.000284 -0.000398 -0.001743   \n",
       "3732  0.012660 -0.011589  0.017275  0.004415  0.004056  0.002603 -0.007437   \n",
       "\n",
       "           252       253       254       255       256       257       258  \\\n",
       "0     0.000057  0.004534  0.000573 -0.001017 -0.002650 -0.001745 -0.005446   \n",
       "1     0.000057  0.004534  0.000573 -0.001017 -0.002650 -0.001745 -0.005446   \n",
       "2     0.000057  0.004534  0.000573 -0.001017 -0.002650 -0.001745 -0.005446   \n",
       "3     0.000057  0.004534  0.000573 -0.001017 -0.002650 -0.001745 -0.005446   \n",
       "4    -0.005555  0.001200  0.001377  0.001342 -0.003245 -0.001757 -0.002752   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003038  0.001468 -0.000879 -0.000320 -0.003316 -0.004705  0.003219   \n",
       "3729 -0.002229  0.004040  0.004713 -0.007425 -0.004403  0.002028  0.007089   \n",
       "3730  0.000073  0.014849  0.014899 -0.004914 -0.013113 -0.001688  0.021950   \n",
       "3731 -0.001788  0.002669  0.003655 -0.006038 -0.006654 -0.002928  0.010203   \n",
       "3732  0.003675  0.001943  0.009161 -0.008587 -0.012396 -0.002843  0.019132   \n",
       "\n",
       "           259       260       261       262       263       264       265  \\\n",
       "0     0.000536  0.004595  0.002023 -0.002019  0.000818  0.000109 -0.002595   \n",
       "1     0.000536  0.004595  0.002023 -0.002019  0.000818  0.000109 -0.002595   \n",
       "2     0.000536  0.004595  0.002023 -0.002019  0.000818  0.000109 -0.002595   \n",
       "3     0.000536  0.004595  0.002023 -0.002019  0.000818  0.000109 -0.002595   \n",
       "4    -0.002166  0.001909 -0.000906 -0.000389  0.006970 -0.003770 -0.001061   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.010647 -0.005367  0.000033 -0.004668 -0.000954  0.000659 -0.009368   \n",
       "3729  0.013938 -0.008490 -0.002974  0.000960  0.003168  0.008375 -0.006365   \n",
       "3730  0.019597 -0.009977 -0.007407  0.015345  0.003677  0.008805 -0.024123   \n",
       "3731  0.006122 -0.003904 -0.009323  0.001753  0.003875  0.007474 -0.007187   \n",
       "3732  0.012000 -0.009684 -0.012039 -0.006680 -0.001790  0.018292 -0.022296   \n",
       "\n",
       "           266       267       268       269       270       271       272  \\\n",
       "0    -0.001626 -0.001233 -0.003847 -0.001084 -0.003103 -0.000539 -0.001490   \n",
       "1    -0.001626 -0.001233 -0.003847 -0.001084 -0.003103 -0.000539 -0.001490   \n",
       "2    -0.001626 -0.001233 -0.003847 -0.001084 -0.003103 -0.000539 -0.001490   \n",
       "3    -0.001626 -0.001233 -0.003847 -0.001084 -0.003103 -0.000539 -0.001490   \n",
       "4    -0.003503  0.000451 -0.004818 -0.000680  0.000683 -0.000096 -0.002419   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.004869 -0.007203 -0.002377  0.005307  0.001868  0.000336 -0.005962   \n",
       "3729  0.009026 -0.010887  0.009911 -0.005031  0.005713 -0.003828 -0.004787   \n",
       "3730  0.021233 -0.005877  0.014373  0.008299 -0.008483 -0.021132 -0.012268   \n",
       "3731  0.012889 -0.004892  0.007988  0.006130 -0.004237 -0.015491 -0.002985   \n",
       "3732  0.005157 -0.001707  0.006351  0.008771 -0.008673 -0.010671 -0.000591   \n",
       "\n",
       "           273       274       275       276       277       278       279  \\\n",
       "0    -0.000440 -0.002124  0.003751 -0.000367 -0.000004  0.001289  0.000944   \n",
       "1    -0.000440 -0.002124  0.003751 -0.000367 -0.000004  0.001289  0.000944   \n",
       "2    -0.000440 -0.002124  0.003751 -0.000367 -0.000004  0.001289  0.000944   \n",
       "3    -0.000440 -0.002124  0.003751 -0.000367 -0.000004  0.001289  0.000944   \n",
       "4    -0.001234  0.002338  0.002906  0.000481  0.001984 -0.003525  0.003165   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002682  0.011439 -0.000544 -0.006361  0.002187 -0.007299  0.000906   \n",
       "3729  0.005120  0.014699 -0.004107 -0.003254 -0.002662 -0.004491 -0.005854   \n",
       "3730 -0.004630  0.018824  0.025683  0.012428 -0.013444 -0.010013  0.014688   \n",
       "3731 -0.002114  0.017150  0.009957  0.005840 -0.008370 -0.010232  0.003640   \n",
       "3732  0.001622  0.016295  0.014802  0.004607 -0.013932 -0.007337  0.005913   \n",
       "\n",
       "           280       281       282       283       284       285       286  \\\n",
       "0    -0.001323 -0.001821  0.004077  0.000467 -0.003403  0.000390  0.000083   \n",
       "1    -0.001323 -0.001821  0.004077  0.000467 -0.003403  0.000390  0.000083   \n",
       "2    -0.001323 -0.001821  0.004077  0.000467 -0.003403  0.000390  0.000083   \n",
       "3    -0.001323 -0.001821  0.004077  0.000467 -0.003403  0.000390  0.000083   \n",
       "4     0.001038  0.003255  0.006741  0.002472 -0.001210 -0.007175 -0.002119   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.009517  0.005618  0.003141  0.003059 -0.009328  0.001501 -0.006116   \n",
       "3729 -0.011401  0.001753  0.009298  0.005717  0.001672  0.004482 -0.007662   \n",
       "3730 -0.015751 -0.010913  0.016157  0.002249 -0.009124  0.020179 -0.012145   \n",
       "3731 -0.000778 -0.005113  0.011798 -0.000847 -0.006984  0.004389 -0.009947   \n",
       "3732 -0.003418  0.004262  0.011847  0.005778 -0.010248  0.014652 -0.010894   \n",
       "\n",
       "           287       288       289       290       291       292       293  \\\n",
       "0     0.000068 -0.004587  0.001150  0.000902 -0.002962 -0.000142  0.000273   \n",
       "1     0.000068 -0.004587  0.001150  0.000902 -0.002962 -0.000142  0.000273   \n",
       "2     0.000068 -0.004587  0.001150  0.000902 -0.002962 -0.000142  0.000273   \n",
       "3     0.000068 -0.004587  0.001150  0.000902 -0.002962 -0.000142  0.000273   \n",
       "4     0.001217  0.000504  0.004485  0.001275 -0.000142 -0.004031 -0.000503   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006799  0.013723 -0.001735  0.001315 -0.001019 -0.002113  0.005620   \n",
       "3729  0.003885  0.007429 -0.005512 -0.001857 -0.006307  0.004985  0.004391   \n",
       "3730  0.002175  0.001706 -0.023561 -0.004761 -0.004586  0.002234 -0.001120   \n",
       "3731  0.002091  0.002128 -0.008301 -0.003548 -0.002596 -0.001915  0.002802   \n",
       "3732  0.005203  0.002770 -0.017036  0.000066 -0.001110  0.002461  0.000046   \n",
       "\n",
       "           294       295       296       297       298       299       300  \\\n",
       "0    -0.003524 -0.002949  0.001273  0.001474 -0.004824  0.000181 -0.000480   \n",
       "1    -0.003524 -0.002949  0.001273  0.001474 -0.004824  0.000181 -0.000480   \n",
       "2    -0.003524 -0.002949  0.001273  0.001474 -0.004824  0.000181 -0.000480   \n",
       "3    -0.003524 -0.002949  0.001273  0.001474 -0.004824  0.000181 -0.000480   \n",
       "4    -0.000118 -0.000904  0.002443  0.001480 -0.005658  0.001009  0.001477   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.004252 -0.003208  0.008023  0.007718  0.000309  0.003004 -0.001190   \n",
       "3729  0.003264 -0.003814  0.001946  0.006608 -0.000272  0.004137  0.000437   \n",
       "3730  0.002910 -0.008645  0.002400  0.004226 -0.021091  0.027466 -0.009177   \n",
       "3731  0.005804 -0.005198 -0.000159  0.004290 -0.005258  0.008769 -0.003895   \n",
       "3732  0.002126 -0.003464  0.003140  0.003174 -0.010905  0.007722 -0.008559   \n",
       "\n",
       "           301       302       303       304       305       306       307  \\\n",
       "0     0.001049  0.000807  0.001808  0.005382 -0.000475 -0.000890  0.003558   \n",
       "1     0.001049  0.000807  0.001808  0.005382 -0.000475 -0.000890  0.003558   \n",
       "2     0.001049  0.000807  0.001808  0.005382 -0.000475 -0.000890  0.003558   \n",
       "3     0.001049  0.000807  0.001808  0.005382 -0.000475 -0.000890  0.003558   \n",
       "4     0.000032 -0.000121 -0.000269  0.005380 -0.001908 -0.001715  0.004143   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003499 -0.002710  0.003349  0.006152  0.005119 -0.002540  0.004748   \n",
       "3729  0.008227 -0.000198  0.004848  0.013631  0.006913  0.000365  0.007394   \n",
       "3730  0.027249  0.013514  0.026456  0.008286  0.003781 -0.004711  0.012006   \n",
       "3731  0.009030  0.004675  0.010884  0.011658 -0.000005  0.001752  0.003290   \n",
       "3732  0.021996  0.010008  0.020515  0.002539  0.004955 -0.001473  0.011002   \n",
       "\n",
       "           308       309       310       311       312       313       314  \\\n",
       "0     0.001836  0.001477 -0.001552 -0.002074  0.004700 -0.000066 -0.001176   \n",
       "1     0.001836  0.001477 -0.001552 -0.002074  0.004700 -0.000066 -0.001176   \n",
       "2     0.001836  0.001477 -0.001552 -0.002074  0.004700 -0.000066 -0.001176   \n",
       "3     0.001836  0.001477 -0.001552 -0.002074  0.004700 -0.000066 -0.001176   \n",
       "4    -0.001303  0.001102  0.002327 -0.003759  0.000230  0.002489  0.000010   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005732 -0.005608  0.013966 -0.004433 -0.000767 -0.000362 -0.003351   \n",
       "3729  0.005059 -0.001847  0.013607 -0.007846  0.004717 -0.005748  0.002003   \n",
       "3730  0.011057 -0.018747  0.020571 -0.000393 -0.003628 -0.016818  0.008840   \n",
       "3731  0.004382 -0.006575  0.011819 -0.004668  0.008086 -0.011359  0.005302   \n",
       "3732  0.009195 -0.010015  0.016480 -0.002444  0.005021 -0.009228  0.010244   \n",
       "\n",
       "           315       316       317       318       319       320       321  \\\n",
       "0     0.000989 -0.000662 -0.001257  0.000928  0.001791  0.001062 -0.000074   \n",
       "1     0.000989 -0.000662 -0.001257  0.000928  0.001791  0.001062 -0.000074   \n",
       "2     0.000989 -0.000662 -0.001257  0.000928  0.001791  0.001062 -0.000074   \n",
       "3     0.000989 -0.000662 -0.001257  0.000928  0.001791  0.001062 -0.000074   \n",
       "4     0.000424 -0.003173 -0.002612 -0.000615  0.001966 -0.004159  0.000836   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.005110  0.000665 -0.002478  0.006172  0.001814 -0.007808  0.000246   \n",
       "3729 -0.001286 -0.002744 -0.005776  0.005774 -0.007844 -0.003944  0.000695   \n",
       "3730  0.010729 -0.023234 -0.016622  0.011651  0.000845 -0.015170 -0.000039   \n",
       "3731  0.005912 -0.014415 -0.007956  0.013822 -0.006185  0.000902  0.003127   \n",
       "3732  0.002444 -0.015393 -0.012663  0.004703  0.004682 -0.004351  0.000899   \n",
       "\n",
       "           322       323       324       325       326       327       328  \\\n",
       "0    -0.000415  0.002280 -0.002980  0.003455  0.002121 -0.001624 -0.001211   \n",
       "1    -0.000415  0.002280 -0.002980  0.003455  0.002121 -0.001624 -0.001211   \n",
       "2    -0.000415  0.002280 -0.002980  0.003455  0.002121 -0.001624 -0.001211   \n",
       "3    -0.000415  0.002280 -0.002980  0.003455  0.002121 -0.001624 -0.001211   \n",
       "4     0.002072  0.001258 -0.001389  0.001128 -0.000521 -0.001216  0.002973   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.009630 -0.001358  0.000954 -0.010159 -0.003002  0.013950 -0.004862   \n",
       "3729  0.014864 -0.014944  0.008213 -0.012458 -0.007477  0.016935 -0.011170   \n",
       "3730  0.037639 -0.020263 -0.012922 -0.019020 -0.007290  0.023110 -0.002444   \n",
       "3731  0.013268 -0.019803 -0.007359 -0.011544 -0.000352  0.016176 -0.002981   \n",
       "3732  0.019752 -0.014971 -0.009357 -0.018577 -0.005397  0.008812 -0.003971   \n",
       "\n",
       "           329       330       331       332       333       334       335  \\\n",
       "0    -0.002276  0.003360 -0.001219  0.004031 -0.001006 -0.000686 -0.002878   \n",
       "1    -0.002276  0.003360 -0.001219  0.004031 -0.001006 -0.000686 -0.002878   \n",
       "2    -0.002276  0.003360 -0.001219  0.004031 -0.001006 -0.000686 -0.002878   \n",
       "3    -0.002276  0.003360 -0.001219  0.004031 -0.001006 -0.000686 -0.002878   \n",
       "4     0.003403  0.001669 -0.000864  0.002378  0.000054  0.001301 -0.004092   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000075  0.004581 -0.004545 -0.005467  0.015710  0.000428  0.003191   \n",
       "3729 -0.002130  0.008920  0.001558  0.000893  0.015684  0.004751  0.005440   \n",
       "3730  0.006725  0.018956  0.017200  0.016808  0.008267  0.003829  0.016535   \n",
       "3731  0.002157  0.010342  0.007120  0.017326  0.007786  0.002741  0.009261   \n",
       "3732  0.001316  0.018620  0.008415  0.013638  0.004677  0.007945  0.008845   \n",
       "\n",
       "           336       337       338       339       340       341       342  \\\n",
       "0     0.003613 -0.001989 -0.003498  0.002401  0.001700  0.001992  0.001545   \n",
       "1     0.003613 -0.001989 -0.003498  0.002401  0.001700  0.001992  0.001545   \n",
       "2     0.003613 -0.001989 -0.003498  0.002401  0.001700  0.001992  0.001545   \n",
       "3     0.003613 -0.001989 -0.003498  0.002401  0.001700  0.001992  0.001545   \n",
       "4     0.001429 -0.002743  0.000202 -0.000045  0.007586  0.001942 -0.002954   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.009304 -0.004565  0.006165  0.005684 -0.004751  0.001306 -0.001641   \n",
       "3729 -0.013494 -0.004280  0.008581  0.004925 -0.010845 -0.002713 -0.008349   \n",
       "3730  0.019509 -0.027012 -0.008585  0.012843  0.003686 -0.008765 -0.025487   \n",
       "3731  0.002631 -0.013040 -0.001853  0.002749 -0.004039 -0.007352 -0.010777   \n",
       "3732  0.014564 -0.016346  0.002480  0.004830 -0.003452 -0.006701 -0.021576   \n",
       "\n",
       "           343       344       345       346       347       348       349  \\\n",
       "0     0.003258 -0.001529 -0.002194 -0.000052  0.002076 -0.000348  0.002046   \n",
       "1     0.003258 -0.001529 -0.002194 -0.000052  0.002076 -0.000348  0.002046   \n",
       "2     0.003258 -0.001529 -0.002194 -0.000052  0.002076 -0.000348  0.002046   \n",
       "3     0.003258 -0.001529 -0.002194 -0.000052  0.002076 -0.000348  0.002046   \n",
       "4     0.002352 -0.000481 -0.003557 -0.005077 -0.002971 -0.002590 -0.002069   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002236  0.001635  0.002357  0.003923  0.000343  0.000104  0.006153   \n",
       "3729  0.003564 -0.001396 -0.000488 -0.002521 -0.003512 -0.003753  0.008247   \n",
       "3730  0.016293  0.000486 -0.002395 -0.019329  0.004896 -0.019846  0.018259   \n",
       "3731  0.005542  0.004292 -0.002150 -0.003898 -0.005910 -0.007625  0.004452   \n",
       "3732  0.013429  0.001949 -0.002483 -0.006322  0.004356 -0.012696  0.007886   \n",
       "\n",
       "           350       351       352       353       354       355       356  \\\n",
       "0    -0.001021  0.002713 -0.001160  0.000913 -0.001759 -0.002985 -0.003507   \n",
       "1    -0.001021  0.002713 -0.001160  0.000913 -0.001759 -0.002985 -0.003507   \n",
       "2    -0.001021  0.002713 -0.001160  0.000913 -0.001759 -0.002985 -0.003507   \n",
       "3    -0.001021  0.002713 -0.001160  0.000913 -0.001759 -0.002985 -0.003507   \n",
       "4    -0.000475  0.001308  0.004418  0.003743 -0.000926 -0.001580 -0.003231   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000845 -0.003499 -0.000623  0.001454  0.006903  0.000206  0.008498   \n",
       "3729 -0.001415  0.003252 -0.002548  0.000187  0.007852 -0.002550  0.008818   \n",
       "3730  0.018928  0.013720  0.006582  0.000795  0.002681  0.003390 -0.002716   \n",
       "3731  0.010729  0.004877  0.002951 -0.001958  0.006977 -0.000784  0.006826   \n",
       "3732  0.012289  0.010349  0.006508 -0.006639  0.003261  0.001961  0.004565   \n",
       "\n",
       "           357       358       359       360       361       362       363  \\\n",
       "0     0.000362 -0.003134 -0.000717  0.000744 -0.000367  0.004645 -0.001242   \n",
       "1     0.000362 -0.003134 -0.000717  0.000744 -0.000367  0.004645 -0.001242   \n",
       "2     0.000362 -0.003134 -0.000717  0.000744 -0.000367  0.004645 -0.001242   \n",
       "3     0.000362 -0.003134 -0.000717  0.000744 -0.000367  0.004645 -0.001242   \n",
       "4     0.001507 -0.001637  0.000145  0.001127  0.004555  0.001480  0.002754   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.014401  0.000590  0.003129 -0.000320  0.003366 -0.005883  0.003562   \n",
       "3729 -0.021217  0.003107  0.000675  0.000446  0.000776 -0.003328 -0.003993   \n",
       "3730 -0.036276  0.005339  0.017486 -0.018151  0.028371  0.011351  0.019997   \n",
       "3731 -0.015553  0.008585  0.006707 -0.008517  0.015776  0.004063  0.007129   \n",
       "3732 -0.017207  0.001639  0.010086 -0.010535  0.019887  0.003894  0.007694   \n",
       "\n",
       "           364       365       366       367       368       369       370  \\\n",
       "0    -0.001945  0.003551  0.001235  0.003249  0.002047 -0.000639  0.001136   \n",
       "1    -0.001945  0.003551  0.001235  0.003249  0.002047 -0.000639  0.001136   \n",
       "2    -0.001945  0.003551  0.001235  0.003249  0.002047 -0.000639  0.001136   \n",
       "3    -0.001945  0.003551  0.001235  0.003249  0.002047 -0.000639  0.001136   \n",
       "4    -0.000601 -0.000234  0.002108  0.006276  0.007515 -0.001051  0.003448   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.006486 -0.000705 -0.000750  0.005155  0.000965  0.000805  0.014078   \n",
       "3729 -0.011411  0.002626 -0.000230  0.002294  0.005033 -0.004298  0.008351   \n",
       "3730 -0.008388  0.011579  0.009312 -0.012051 -0.012738 -0.024657  0.031917   \n",
       "3731 -0.011187  0.003384 -0.001758  0.003525 -0.003497 -0.004741  0.008018   \n",
       "3732 -0.004135  0.008260 -0.002455 -0.001802  0.000866 -0.015609  0.012888   \n",
       "\n",
       "           371       372       373       374       375       376       377  \\\n",
       "0    -0.001539  0.000078  0.001002 -0.002423 -0.001460  0.001917  0.003565   \n",
       "1    -0.001539  0.000078  0.001002 -0.002423 -0.001460  0.001917  0.003565   \n",
       "2    -0.001539  0.000078  0.001002 -0.002423 -0.001460  0.001917  0.003565   \n",
       "3    -0.001539  0.000078  0.001002 -0.002423 -0.001460  0.001917  0.003565   \n",
       "4    -0.000997  0.002500  0.003340 -0.000701 -0.002149  0.002387  0.000185   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001400  0.019229 -0.000425  0.005291 -0.000217 -0.002394 -0.001999   \n",
       "3729  0.010919  0.014025 -0.001986  0.003172  0.003282 -0.001799 -0.004967   \n",
       "3730  0.018775  0.023695 -0.010382  0.012623 -0.015960  0.011013 -0.005605   \n",
       "3731  0.011475  0.016289 -0.007971  0.006130 -0.006455  0.006294 -0.002760   \n",
       "3732  0.006018  0.017801 -0.021405  0.015659 -0.010653  0.012094 -0.007717   \n",
       "\n",
       "           378       379       380       381       382       383       384  \\\n",
       "0     0.005322 -0.000519 -0.001487 -0.003688  0.002700 -0.000977 -0.005536   \n",
       "1     0.005322 -0.000519 -0.001487 -0.003688  0.002700 -0.000977 -0.005536   \n",
       "2     0.005322 -0.000519 -0.001487 -0.003688  0.002700 -0.000977 -0.005536   \n",
       "3     0.005322 -0.000519 -0.001487 -0.003688  0.002700 -0.000977 -0.005536   \n",
       "4     0.003405  0.000774  0.002302  0.000405 -0.002441 -0.004189 -0.006633   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005366  0.003740 -0.009055 -0.014639  0.000942  0.006496  0.003931   \n",
       "3729  0.007089  0.006426 -0.004568 -0.015166  0.002733  0.006124  0.006268   \n",
       "3730  0.029884  0.013076  0.003900 -0.024338 -0.003345  0.010329 -0.015505   \n",
       "3731  0.016162  0.010559 -0.001604 -0.017525  0.001670  0.006313  0.000494   \n",
       "3732  0.032641  0.013207 -0.000369 -0.018693 -0.001221  0.006062  0.001332   \n",
       "\n",
       "           385       386       387       388       389       390       391  \\\n",
       "0    -0.000425  0.001897  0.002086  0.002615  0.002713  0.002094  0.001805   \n",
       "1    -0.000425  0.001897  0.002086  0.002615  0.002713  0.002094  0.001805   \n",
       "2    -0.000425  0.001897  0.002086  0.002615  0.002713  0.002094  0.001805   \n",
       "3    -0.000425  0.001897  0.002086  0.002615  0.002713  0.002094  0.001805   \n",
       "4    -0.001021  0.000057  0.003429  0.004212  0.006550  0.005122  0.000868   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000031  0.005376  0.002595 -0.002620 -0.002217  0.005306  0.002845   \n",
       "3729 -0.004842  0.001889 -0.004173 -0.010594  0.007614  0.006871  0.012637   \n",
       "3730  0.002316  0.011643 -0.011254 -0.024316 -0.002473  0.035248  0.037451   \n",
       "3731 -0.001435  0.007972 -0.003608 -0.013014  0.007858  0.009759  0.023070   \n",
       "3732  0.001256  0.000121 -0.009742 -0.024610  0.006930  0.022306  0.029941   \n",
       "\n",
       "           392       393       394       395       396       397       398  \\\n",
       "0    -0.000191  0.002261  0.003197 -0.001123  0.002689  0.000792 -0.000754   \n",
       "1    -0.000191  0.002261  0.003197 -0.001123  0.002689  0.000792 -0.000754   \n",
       "2    -0.000191  0.002261  0.003197 -0.001123  0.002689  0.000792 -0.000754   \n",
       "3    -0.000191  0.002261  0.003197 -0.001123  0.002689  0.000792 -0.000754   \n",
       "4    -0.000535  0.001214  0.003614 -0.002960  0.003009  0.004533 -0.001410   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.004135 -0.009981 -0.015908  0.000012 -0.010344 -0.002937 -0.006903   \n",
       "3729  0.007013 -0.004360 -0.013516 -0.001774 -0.015011 -0.005784 -0.014648   \n",
       "3730  0.017364 -0.009418  0.008618 -0.005707 -0.003262 -0.010717 -0.014498   \n",
       "3731  0.008099 -0.002389 -0.000982  0.004796 -0.005873 -0.005400 -0.010391   \n",
       "3732  0.013145 -0.000021  0.004163 -0.001029 -0.004920 -0.010422 -0.017993   \n",
       "\n",
       "           399       400       401       402       403       404       405  \\\n",
       "0     0.002205  0.003709  0.000078 -0.003511  0.001373 -0.000251  0.002364   \n",
       "1     0.002205  0.003709  0.000078 -0.003511  0.001373 -0.000251  0.002364   \n",
       "2     0.002205  0.003709  0.000078 -0.003511  0.001373 -0.000251  0.002364   \n",
       "3     0.002205  0.003709  0.000078 -0.003511  0.001373 -0.000251  0.002364   \n",
       "4     0.001783  0.003561  0.002296 -0.005875  0.004130 -0.000021  0.002359   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.005679 -0.001248  0.001291  0.003133 -0.000261  0.003160 -0.001722   \n",
       "3729 -0.006736 -0.002838 -0.002555  0.006432  0.003340  0.001223 -0.005103   \n",
       "3730 -0.008410 -0.007603 -0.002047  0.001500  0.005096  0.005138 -0.002495   \n",
       "3731 -0.009759  0.003046 -0.000014  0.005470 -0.000112 -0.002741 -0.003076   \n",
       "3732 -0.003113 -0.010774 -0.010129  0.004964 -0.007793 -0.004282 -0.003061   \n",
       "\n",
       "           406       407       408       409       410       411       412  \\\n",
       "0     0.003308  0.000879  0.001954 -0.001315 -0.002099 -0.001858  0.001103   \n",
       "1     0.003308  0.000879  0.001954 -0.001315 -0.002099 -0.001858  0.001103   \n",
       "2     0.003308  0.000879  0.001954 -0.001315 -0.002099 -0.001858  0.001103   \n",
       "3     0.003308  0.000879  0.001954 -0.001315 -0.002099 -0.001858  0.001103   \n",
       "4     0.000964 -0.002601  0.001525 -0.003411  0.002889 -0.001738  0.001603   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002306  0.010595  0.005444  0.001046 -0.005410 -0.011160 -0.002319   \n",
       "3729 -0.012248  0.006044  0.004615  0.000105 -0.002794 -0.009180 -0.002855   \n",
       "3730 -0.004317 -0.003619 -0.014649 -0.014603  0.002404 -0.008988 -0.013330   \n",
       "3731 -0.005538  0.003649  0.008660 -0.006005 -0.003371 -0.006139 -0.001488   \n",
       "3732 -0.006599 -0.002866  0.002173 -0.014331 -0.001790 -0.005916 -0.008464   \n",
       "\n",
       "           413       414       415       416       417       418       419  \\\n",
       "0     0.001763 -0.001152 -0.000307  0.005476  0.004153 -0.000374 -0.000440   \n",
       "1     0.001763 -0.001152 -0.000307  0.005476  0.004153 -0.000374 -0.000440   \n",
       "2     0.001763 -0.001152 -0.000307  0.005476  0.004153 -0.000374 -0.000440   \n",
       "3     0.001763 -0.001152 -0.000307  0.005476  0.004153 -0.000374 -0.000440   \n",
       "4     0.004800  0.001794  0.001562  0.003128  0.002610  0.003382 -0.002742   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006296 -0.000423 -0.000613 -0.004740 -0.005228 -0.006163 -0.004335   \n",
       "3729  0.008247 -0.000526 -0.001999 -0.006035 -0.003380 -0.006754 -0.006043   \n",
       "3730  0.020069  0.001229 -0.009486 -0.006222  0.019939 -0.026626 -0.023253   \n",
       "3731  0.005504 -0.003258  0.000304 -0.004785  0.007382 -0.011659 -0.014056   \n",
       "3732  0.010317 -0.008868 -0.001481 -0.009951  0.005717 -0.011056 -0.028506   \n",
       "\n",
       "           420       421       422       423       424       425       426  \\\n",
       "0    -0.002342  0.000334  0.002125  0.005708  0.002033  0.001523 -0.000570   \n",
       "1    -0.002342  0.000334  0.002125  0.005708  0.002033  0.001523 -0.000570   \n",
       "2    -0.002342  0.000334  0.002125  0.005708  0.002033  0.001523 -0.000570   \n",
       "3    -0.002342  0.000334  0.002125  0.005708  0.002033  0.001523 -0.000570   \n",
       "4     0.000425 -0.001814  0.000590  0.004957  0.004323 -0.000667 -0.001308   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002118  0.001484  0.010316 -0.015697 -0.002700 -0.001127 -0.001774   \n",
       "3729 -0.003554 -0.000870  0.006773 -0.018158 -0.008147 -0.003155 -0.003848   \n",
       "3730 -0.019233 -0.018837 -0.020334 -0.013728  0.013061  0.001492 -0.004557   \n",
       "3731 -0.005912 -0.005795 -0.004425 -0.008319  0.003497  0.003116 -0.005650   \n",
       "3732 -0.010931 -0.007888 -0.015503 -0.020673  0.000117  0.010678 -0.012382   \n",
       "\n",
       "           427       428       429       430       431       432       433  \\\n",
       "0     0.003404 -0.000775 -0.000653 -0.002999  0.004228 -0.000514 -0.000660   \n",
       "1     0.003404 -0.000775 -0.000653 -0.002999  0.004228 -0.000514 -0.000660   \n",
       "2     0.003404 -0.000775 -0.000653 -0.002999  0.004228 -0.000514 -0.000660   \n",
       "3     0.003404 -0.000775 -0.000653 -0.002999  0.004228 -0.000514 -0.000660   \n",
       "4     0.004177  0.005218 -0.004517 -0.001381  0.001946 -0.000935 -0.000384   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002004 -0.000502 -0.000777  0.003470 -0.008865 -0.007892 -0.003874   \n",
       "3729 -0.003200  0.001121 -0.003149  0.003653 -0.014829 -0.011101 -0.006291   \n",
       "3730 -0.000197 -0.014610 -0.000706 -0.014485  0.004243 -0.014393 -0.000101   \n",
       "3731 -0.006859 -0.004408 -0.004246 -0.006945 -0.001318 -0.007266  0.001768   \n",
       "3732 -0.011516 -0.008335 -0.003936 -0.000916  0.003030 -0.005316  0.001894   \n",
       "\n",
       "           434       435       436       437       438       439       440  \\\n",
       "0     0.005725  0.003634  0.003098  0.000578  0.001723 -0.001510 -0.003241   \n",
       "1     0.005725  0.003634  0.003098  0.000578  0.001723 -0.001510 -0.003241   \n",
       "2     0.005725  0.003634  0.003098  0.000578  0.001723 -0.001510 -0.003241   \n",
       "3     0.005725  0.003634  0.003098  0.000578  0.001723 -0.001510 -0.003241   \n",
       "4     0.005522  0.001916 -0.000224 -0.001612  0.000215 -0.003706 -0.004424   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005461 -0.001200  0.004115  0.003855  0.004767  0.006461  0.000979   \n",
       "3729  0.002739 -0.002552  0.010011  0.004569  0.001945  0.009585 -0.005979   \n",
       "3730  0.003122 -0.018264  0.039440  0.014422  0.032140  0.012190 -0.003571   \n",
       "3731  0.009522 -0.006623  0.018357  0.004470  0.014693  0.001414 -0.003070   \n",
       "3732 -0.000108 -0.013475  0.030931  0.004079  0.032401  0.002906  0.003396   \n",
       "\n",
       "           441       442       443       444       445       446       447  \\\n",
       "0     0.000908 -0.000982 -0.001680 -0.000604  0.001954  0.000015 -0.001063   \n",
       "1     0.000908 -0.000982 -0.001680 -0.000604  0.001954  0.000015 -0.001063   \n",
       "2     0.000908 -0.000982 -0.001680 -0.000604  0.001954  0.000015 -0.001063   \n",
       "3     0.000908 -0.000982 -0.001680 -0.000604  0.001954  0.000015 -0.001063   \n",
       "4     0.003279  0.000249 -0.000537  0.002109 -0.002996  0.005084 -0.001674   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.008012  0.002827  0.006030  0.005380 -0.000727  0.008595  0.002637   \n",
       "3729  0.009551  0.005243  0.003766  0.007488  0.003495  0.003641 -0.001071   \n",
       "3730  0.016807  0.019382  0.004898  0.012955  0.000970 -0.007349 -0.002431   \n",
       "3731  0.007550  0.013773  0.004944  0.005370  0.002428 -0.001078 -0.002055   \n",
       "3732  0.017955  0.018098  0.004536  0.012333  0.006470 -0.001719 -0.005484   \n",
       "\n",
       "           448       449       450       451       452       453       454  \\\n",
       "0    -0.002327  0.000408  0.003179  0.001682 -0.001548  0.001988  0.000899   \n",
       "1    -0.002327  0.000408  0.003179  0.001682 -0.001548  0.001988  0.000899   \n",
       "2    -0.002327  0.000408  0.003179  0.001682 -0.001548  0.001988  0.000899   \n",
       "3    -0.002327  0.000408  0.003179  0.001682 -0.001548  0.001988  0.000899   \n",
       "4     0.002071 -0.000332  0.002586  0.004121 -0.004687  0.003246 -0.001835   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.009039  0.007097 -0.000301 -0.009865  0.001483 -0.004066 -0.002139   \n",
       "3729 -0.009299  0.010573 -0.001366 -0.006534  0.004187 -0.003331 -0.003529   \n",
       "3730 -0.030710  0.001747  0.012075  0.000942  0.014193  0.017416  0.001037   \n",
       "3731 -0.011071  0.001914  0.001566  0.003519  0.007066  0.007528  0.000634   \n",
       "3732 -0.013527 -0.001450 -0.001449  0.002910  0.012856  0.010790 -0.004167   \n",
       "\n",
       "           455       456       457       458       459       460       461  \\\n",
       "0     0.000880 -0.002557  0.000445  0.002472  0.002234  0.001928 -0.000725   \n",
       "1     0.000880 -0.002557  0.000445  0.002472  0.002234  0.001928 -0.000725   \n",
       "2     0.000880 -0.002557  0.000445  0.002472  0.002234  0.001928 -0.000725   \n",
       "3     0.000880 -0.002557  0.000445  0.002472  0.002234  0.001928 -0.000725   \n",
       "4    -0.001675  0.001736  0.000093  0.000339  0.002752  0.002935 -0.002385   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004218  0.001802 -0.002987 -0.001203 -0.002728 -0.006267 -0.010614   \n",
       "3729 -0.013869  0.005201 -0.006242 -0.000693 -0.005300 -0.000727 -0.016198   \n",
       "3730 -0.024588  0.006512 -0.018061  0.000211 -0.005669 -0.017656 -0.007124   \n",
       "3731 -0.013057  0.006801 -0.007150 -0.001329  0.005509 -0.006638 -0.008966   \n",
       "3732 -0.024683  0.006574 -0.017193  0.000104 -0.005966 -0.021555 -0.012749   \n",
       "\n",
       "           462       463       464       465       466       467       468  \\\n",
       "0    -0.000728 -0.000882  0.002811 -0.000703  0.000945  0.002185  0.001727   \n",
       "1    -0.000728 -0.000882  0.002811 -0.000703  0.000945  0.002185  0.001727   \n",
       "2    -0.000728 -0.000882  0.002811 -0.000703  0.000945  0.002185  0.001727   \n",
       "3    -0.000728 -0.000882  0.002811 -0.000703  0.000945  0.002185  0.001727   \n",
       "4    -0.000399 -0.000077 -0.000199 -0.005806 -0.000275 -0.002779  0.003778   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001046  0.006791  0.004493 -0.003752  0.002660  0.003096  0.000701   \n",
       "3729 -0.002159  0.000185  0.006418 -0.000167 -0.001727  0.004497  0.000777   \n",
       "3730  0.005366 -0.004698  0.002554  0.002845 -0.006927  0.005540  0.007238   \n",
       "3731  0.001817 -0.000446  0.002303  0.005942 -0.007323 -0.002063  0.001885   \n",
       "3732  0.003234 -0.004941 -0.001311  0.007025 -0.005787 -0.006916  0.006549   \n",
       "\n",
       "           469       470       471       472       473       474       475  \\\n",
       "0    -0.001638 -0.000847 -0.001676 -0.000684 -0.002657  0.000687  0.003456   \n",
       "1    -0.001638 -0.000847 -0.001676 -0.000684 -0.002657  0.000687  0.003456   \n",
       "2    -0.001638 -0.000847 -0.001676 -0.000684 -0.002657  0.000687  0.003456   \n",
       "3    -0.001638 -0.000847 -0.001676 -0.000684 -0.002657  0.000687  0.003456   \n",
       "4    -0.000377  0.001801  0.000329 -0.001067 -0.008418 -0.002545  0.001998   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.007226  0.005190  0.004482 -0.004929  0.004866 -0.007306  0.003396   \n",
       "3729 -0.007689  0.000057 -0.003955 -0.002587  0.006564 -0.004413  0.008551   \n",
       "3730 -0.009931  0.004671 -0.018042  0.003460 -0.028388 -0.019505  0.031830   \n",
       "3731 -0.004651  0.003229 -0.012486  0.006853 -0.004331 -0.007927  0.014663   \n",
       "3732 -0.011008  0.001999 -0.015398  0.009352 -0.019394 -0.013761  0.013530   \n",
       "\n",
       "           476       477       478       479       480       481       482  \\\n",
       "0     0.001075  0.004571 -0.000448  0.003708  0.002320 -0.002248  0.002350   \n",
       "1     0.001075  0.004571 -0.000448  0.003708  0.002320 -0.002248  0.002350   \n",
       "2     0.001075  0.004571 -0.000448  0.003708  0.002320 -0.002248  0.002350   \n",
       "3     0.001075  0.004571 -0.000448  0.003708  0.002320 -0.002248  0.002350   \n",
       "4     0.000289  0.006671 -0.000863  0.001471  0.002330 -0.002669  0.003191   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000161 -0.003619 -0.001752  0.006505  0.001223 -0.000642 -0.003107   \n",
       "3729  0.005267 -0.005874  0.000892  0.004115  0.000442  0.002525 -0.002661   \n",
       "3730  0.023013  0.027218 -0.009189  0.010745  0.020323  0.010224  0.014833   \n",
       "3731  0.014519  0.005284  0.001951  0.005234  0.014066 -0.001348  0.006465   \n",
       "3732  0.021384  0.010180 -0.000971  0.003506  0.014560  0.005004  0.011072   \n",
       "\n",
       "           483       484       485       486       487       488       489  \\\n",
       "0    -0.001119  0.001038 -0.001551  0.002100 -0.000906  0.004947 -0.000802   \n",
       "1    -0.001119  0.001038 -0.001551  0.002100 -0.000906  0.004947 -0.000802   \n",
       "2    -0.001119  0.001038 -0.001551  0.002100 -0.000906  0.004947 -0.000802   \n",
       "3    -0.001119  0.001038 -0.001551  0.002100 -0.000906  0.004947 -0.000802   \n",
       "4    -0.002714 -0.002240 -0.003264  0.005114  0.000672  0.007668 -0.000469   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005990  0.006323 -0.006207 -0.004846 -0.006554 -0.001716  0.009737   \n",
       "3729  0.009240  0.012356 -0.008031 -0.002943 -0.010946 -0.001459  0.010621   \n",
       "3730  0.009064  0.015039  0.016383 -0.016678 -0.013427 -0.009442  0.019582   \n",
       "3731  0.008489  0.010875  0.000297 -0.007541 -0.006323  0.004360  0.010662   \n",
       "3732  0.025217  0.011372  0.010613 -0.005759 -0.010585 -0.000928  0.014250   \n",
       "\n",
       "           490       491       492       493       494       495       496  \\\n",
       "0     0.001689 -0.004100  0.000364  0.000830  0.000120 -0.000223  0.001040   \n",
       "1     0.001689 -0.004100  0.000364  0.000830  0.000120 -0.000223  0.001040   \n",
       "2     0.001689 -0.004100  0.000364  0.000830  0.000120 -0.000223  0.001040   \n",
       "3     0.001689 -0.004100  0.000364  0.000830  0.000120 -0.000223  0.001040   \n",
       "4     0.002221 -0.002685  0.000960  0.001591  0.006351  0.003499 -0.000134   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001808  0.007576  0.001384 -0.007787 -0.001534 -0.000251 -0.004796   \n",
       "3729 -0.003816  0.004586 -0.002287 -0.007059 -0.001578 -0.006514 -0.008255   \n",
       "3730 -0.004413  0.008305  0.010303 -0.011631 -0.006837 -0.006635 -0.027491   \n",
       "3731 -0.002240  0.007829  0.002328 -0.005769  0.001362 -0.004073 -0.014683   \n",
       "3732 -0.007672  0.009629 -0.001267 -0.016490 -0.006160 -0.010737 -0.019993   \n",
       "\n",
       "           497       498  ...       783       784       785       786  \\\n",
       "0     0.000934  0.000707  ... -0.001537 -0.001086 -0.000830 -0.003101   \n",
       "1     0.000934  0.000707  ... -0.001537 -0.001086 -0.000830 -0.003101   \n",
       "2     0.000934  0.000707  ... -0.001537 -0.001086 -0.000830 -0.003101   \n",
       "3     0.000934  0.000707  ... -0.001537 -0.001086 -0.000830 -0.003101   \n",
       "4     0.002730  0.001331  ... -0.002630 -0.003356  0.000393 -0.002291   \n",
       "...        ...       ...  ...       ...       ...       ...       ...   \n",
       "3728  0.002849 -0.001765  ... -0.012552  0.000978  0.000258  0.002048   \n",
       "3729  0.000596 -0.002704  ... -0.008311  0.001148  0.004365  0.009697   \n",
       "3730  0.000509  0.020468  ... -0.015112 -0.008030  0.004720 -0.007456   \n",
       "3731 -0.001214  0.011927  ... -0.001589  0.000218 -0.001899 -0.001992   \n",
       "3732 -0.002407  0.016972  ... -0.013100  0.000624 -0.002404  0.002981   \n",
       "\n",
       "           787       788       789       790       791       792       793  \\\n",
       "0    -0.004206 -0.001650 -0.002398  0.000871 -0.005719  0.001594  0.002326   \n",
       "1    -0.004206 -0.001650 -0.002398  0.000871 -0.005719  0.001594  0.002326   \n",
       "2    -0.004206 -0.001650 -0.002398  0.000871 -0.005719  0.001594  0.002326   \n",
       "3    -0.004206 -0.001650 -0.002398  0.000871 -0.005719  0.001594  0.002326   \n",
       "4    -0.001182  0.003481  0.001475  0.005357 -0.003948  0.002462  0.003202   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.007879  0.009314  0.008956  0.002020  0.007271 -0.010684 -0.001880   \n",
       "3729  0.007542  0.008372  0.011007 -0.006341  0.005186 -0.013810 -0.004673   \n",
       "3730  0.000618  0.005027  0.002694 -0.015995 -0.019500 -0.028238 -0.010752   \n",
       "3731  0.002621  0.001530  0.002387 -0.008391 -0.012540 -0.016711 -0.006777   \n",
       "3732  0.007122  0.000406 -0.001767 -0.005259 -0.021698 -0.025433 -0.006802   \n",
       "\n",
       "           794       795       796       797       798       799       800  \\\n",
       "0     0.001783  0.002689 -0.000361 -0.003004 -0.003659 -0.002701  0.001777   \n",
       "1     0.001783  0.002689 -0.000361 -0.003004 -0.003659 -0.002701  0.001777   \n",
       "2     0.001783  0.002689 -0.000361 -0.003004 -0.003659 -0.002701  0.001777   \n",
       "3     0.001783  0.002689 -0.000361 -0.003004 -0.003659 -0.002701  0.001777   \n",
       "4     0.003211  0.001639  0.001221  0.000880 -0.005832 -0.002853  0.000222   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000858 -0.014676  0.005044  0.005221 -0.005973  0.004338  0.011733   \n",
       "3729  0.003172 -0.013951  0.010596  0.006391 -0.001467  0.006704  0.013586   \n",
       "3730 -0.014035 -0.000292  0.014580 -0.004342  0.007126  0.006651  0.017305   \n",
       "3731  0.001336 -0.001685  0.009508  0.000790  0.003174  0.008983  0.015720   \n",
       "3732  0.003746 -0.004397  0.012926 -0.003999  0.012382  0.011610  0.009668   \n",
       "\n",
       "           801       802       803       804       805       806       807  \\\n",
       "0    -0.000715  0.002708 -0.002867 -0.000065  0.003624 -0.000393  0.003450   \n",
       "1    -0.000715  0.002708 -0.002867 -0.000065  0.003624 -0.000393  0.003450   \n",
       "2    -0.000715  0.002708 -0.002867 -0.000065  0.003624 -0.000393  0.003450   \n",
       "3    -0.000715  0.002708 -0.002867 -0.000065  0.003624 -0.000393  0.003450   \n",
       "4    -0.006092  0.001428  0.001975  0.000197  0.004161  0.001770  0.008039   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001096 -0.003425  0.003824  0.000326 -0.006428 -0.001399 -0.000871   \n",
       "3729  0.001879 -0.001492  0.004024  0.004107 -0.010119 -0.005161 -0.003159   \n",
       "3730  0.008416  0.000543 -0.005400  0.023840 -0.029415 -0.004122 -0.012762   \n",
       "3731  0.000909 -0.000162 -0.009881  0.014723 -0.012467 -0.003250 -0.003016   \n",
       "3732 -0.001853 -0.000958 -0.004254  0.015222 -0.016130 -0.007151 -0.005504   \n",
       "\n",
       "           808       809       810       811       812       813       814  \\\n",
       "0     0.000169 -0.002885  0.001262 -0.005958 -0.000040 -0.001690  0.001520   \n",
       "1     0.000169 -0.002885  0.001262 -0.005958 -0.000040 -0.001690  0.001520   \n",
       "2     0.000169 -0.002885  0.001262 -0.005958 -0.000040 -0.001690  0.001520   \n",
       "3     0.000169 -0.002885  0.001262 -0.005958 -0.000040 -0.001690  0.001520   \n",
       "4    -0.005985 -0.000075  0.003566 -0.004253 -0.000210 -0.000986 -0.005373   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.005319 -0.007890  0.008914  0.000185 -0.001518 -0.015826 -0.000367   \n",
       "3729 -0.002485 -0.010612  0.009537  0.000890  0.000024 -0.014705  0.003096   \n",
       "3730 -0.026895 -0.020959  0.015965  0.010703 -0.014607 -0.026883  0.012530   \n",
       "3731 -0.011085 -0.015328  0.007870  0.008461 -0.003044 -0.017816  0.005057   \n",
       "3732 -0.016955 -0.015279  0.012218  0.010812 -0.002164 -0.019149  0.006448   \n",
       "\n",
       "           815       816       817       818       819       820       821  \\\n",
       "0    -0.001787 -0.000589  0.000604  0.002386 -0.003599 -0.001565  0.002391   \n",
       "1    -0.001787 -0.000589  0.000604  0.002386 -0.003599 -0.001565  0.002391   \n",
       "2    -0.001787 -0.000589  0.000604  0.002386 -0.003599 -0.001565  0.002391   \n",
       "3    -0.001787 -0.000589  0.000604  0.002386 -0.003599 -0.001565  0.002391   \n",
       "4     0.000081 -0.000674 -0.004144 -0.001171 -0.000937 -0.002357 -0.000329   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000850  0.003719 -0.005024  0.000727  0.003136 -0.005319  0.003071   \n",
       "3729  0.003134 -0.007964 -0.004093  0.002893  0.006328 -0.005840  0.000247   \n",
       "3730 -0.000562 -0.006707 -0.038329  0.026691 -0.011008  0.005045 -0.015814   \n",
       "3731 -0.002679 -0.004189 -0.016218  0.004340 -0.003966 -0.001803 -0.005356   \n",
       "3732 -0.002966 -0.008948 -0.031693  0.015216 -0.005333  0.000337 -0.010212   \n",
       "\n",
       "           822       823       824       825       826       827       828  \\\n",
       "0     0.003210 -0.000705  0.001907 -0.002810 -0.000008 -0.002139  0.000568   \n",
       "1     0.003210 -0.000705  0.001907 -0.002810 -0.000008 -0.002139  0.000568   \n",
       "2     0.003210 -0.000705  0.001907 -0.002810 -0.000008 -0.002139  0.000568   \n",
       "3     0.003210 -0.000705  0.001907 -0.002810 -0.000008 -0.002139  0.000568   \n",
       "4     0.003969  0.002840  0.002934 -0.001471 -0.000755 -0.003990  0.001767   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004785  0.000367 -0.006203 -0.001429 -0.001482 -0.010280 -0.005736   \n",
       "3729 -0.005536  0.000319 -0.003596  0.000071  0.000527 -0.008503 -0.005144   \n",
       "3730 -0.004127  0.001770 -0.002015 -0.031149 -0.006165 -0.015228 -0.009631   \n",
       "3731 -0.000749  0.005549 -0.003596 -0.011181 -0.008410 -0.008732  0.001223   \n",
       "3732 -0.003538 -0.001369 -0.002443 -0.019411 -0.015162 -0.003484 -0.000846   \n",
       "\n",
       "           829       830       831       832       833       834       835  \\\n",
       "0    -0.000566 -0.000869 -0.000170 -0.001529  0.001963 -0.001766 -0.001744   \n",
       "1    -0.000566 -0.000869 -0.000170 -0.001529  0.001963 -0.001766 -0.001744   \n",
       "2    -0.000566 -0.000869 -0.000170 -0.001529  0.001963 -0.001766 -0.001744   \n",
       "3    -0.000566 -0.000869 -0.000170 -0.001529  0.001963 -0.001766 -0.001744   \n",
       "4    -0.001530  0.003982 -0.003781 -0.004714 -0.001269 -0.002527  0.000521   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003152  0.000891  0.004027 -0.005992  0.012622  0.001295  0.002236   \n",
       "3729  0.005245 -0.005013 -0.002808 -0.014041  0.014760  0.005927  0.009546   \n",
       "3730  0.013656 -0.024843  0.006111 -0.014701 -0.005864 -0.002459  0.015309   \n",
       "3731  0.005539 -0.012825 -0.007292 -0.014062  0.007041  0.000488  0.012103   \n",
       "3732  0.005077 -0.024000 -0.001397 -0.016068  0.005202  0.001788  0.016341   \n",
       "\n",
       "           836       837       838       839       840       841       842  \\\n",
       "0    -0.002330  0.002384 -0.000854 -0.002230  0.000648 -0.001548  0.000798   \n",
       "1    -0.002330  0.002384 -0.000854 -0.002230  0.000648 -0.001548  0.000798   \n",
       "2    -0.002330  0.002384 -0.000854 -0.002230  0.000648 -0.001548  0.000798   \n",
       "3    -0.002330  0.002384 -0.000854 -0.002230  0.000648 -0.001548  0.000798   \n",
       "4    -0.000423 -0.000273 -0.001088  0.003464  0.000597 -0.004676 -0.000140   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.003848 -0.011573 -0.001941 -0.001491 -0.002082 -0.001376  0.012701   \n",
       "3729  0.001232 -0.001943 -0.001655  0.003960 -0.002311  0.003315  0.009139   \n",
       "3730 -0.005177  0.004746  0.007240  0.011619  0.008346  0.023003  0.029756   \n",
       "3731 -0.000710  0.003932  0.001086  0.008904  0.004828  0.002650  0.019244   \n",
       "3732  0.002113  0.004559  0.001758  0.014038  0.003426  0.008371  0.022990   \n",
       "\n",
       "           843       844       845       846       847       848       849  \\\n",
       "0     0.000821 -0.000661  0.001181 -0.003180  0.001081  0.000580 -0.000527   \n",
       "1     0.000821 -0.000661  0.001181 -0.003180  0.001081  0.000580 -0.000527   \n",
       "2     0.000821 -0.000661  0.001181 -0.003180  0.001081  0.000580 -0.000527   \n",
       "3     0.000821 -0.000661  0.001181 -0.003180  0.001081  0.000580 -0.000527   \n",
       "4    -0.001223 -0.002961 -0.000602 -0.009565  0.002376  0.003120 -0.001259   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004406 -0.001867 -0.007065 -0.013587 -0.006844  0.004582  0.004665   \n",
       "3729  0.002507  0.000804 -0.003596 -0.013006 -0.008551  0.000424  0.004526   \n",
       "3730 -0.028776 -0.005504  0.023072 -0.011226  0.020669 -0.010567 -0.002758   \n",
       "3731 -0.010806 -0.003380  0.010062 -0.003819  0.003893 -0.002207 -0.002617   \n",
       "3732 -0.025277  0.000965  0.017487  0.000796  0.005498 -0.014430 -0.007339   \n",
       "\n",
       "           850       851       852       853       854       855       856  \\\n",
       "0     0.003656 -0.001532 -0.003532 -0.000041 -0.001449 -0.003155 -0.000677   \n",
       "1     0.003656 -0.001532 -0.003532 -0.000041 -0.001449 -0.003155 -0.000677   \n",
       "2     0.003656 -0.001532 -0.003532 -0.000041 -0.001449 -0.003155 -0.000677   \n",
       "3     0.003656 -0.001532 -0.003532 -0.000041 -0.001449 -0.003155 -0.000677   \n",
       "4     0.001151 -0.001029 -0.004537  0.001997 -0.003168 -0.000689 -0.002715   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003250  0.001550 -0.002634 -0.000942 -0.003904  0.008197 -0.006898   \n",
       "3729  0.004500 -0.007596 -0.007115 -0.007660  0.000606  0.009416 -0.005864   \n",
       "3730 -0.010072 -0.030236 -0.011779 -0.026493 -0.007765 -0.000602 -0.004721   \n",
       "3731  0.003910 -0.018076 -0.011648 -0.009684 -0.003181  0.004471 -0.003760   \n",
       "3732  0.000351 -0.018285 -0.016549 -0.019544 -0.003802  0.006837  0.000597   \n",
       "\n",
       "           857       858       859       860       861       862       863  \\\n",
       "0     0.003672  0.001033 -0.001710  0.002211  0.003153 -0.003671 -0.000067   \n",
       "1     0.003672  0.001033 -0.001710  0.002211  0.003153 -0.003671 -0.000067   \n",
       "2     0.003672  0.001033 -0.001710  0.002211  0.003153 -0.003671 -0.000067   \n",
       "3     0.003672  0.001033 -0.001710  0.002211  0.003153 -0.003671 -0.000067   \n",
       "4     0.000055 -0.001225 -0.004873  0.000306  0.003160 -0.003587  0.001130   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001222 -0.002718  0.004297  0.002277 -0.002550 -0.018845  0.000523   \n",
       "3729  0.001234 -0.004109 -0.001112  0.002834 -0.004281 -0.027291  0.005018   \n",
       "3730 -0.017744  0.001321  0.009532 -0.000188 -0.015428 -0.036221  0.047065   \n",
       "3731 -0.004021  0.000293  0.008409  0.001463  0.000249 -0.020276  0.012677   \n",
       "3732 -0.004795 -0.002122  0.007729 -0.004506 -0.007646 -0.021625  0.026795   \n",
       "\n",
       "           864       865       866       867       868       869       870  \\\n",
       "0    -0.001008 -0.000735 -0.000050 -0.001250  0.000479  0.000665 -0.000275   \n",
       "1    -0.001008 -0.000735 -0.000050 -0.001250  0.000479  0.000665 -0.000275   \n",
       "2    -0.001008 -0.000735 -0.000050 -0.001250  0.000479  0.000665 -0.000275   \n",
       "3    -0.001008 -0.000735 -0.000050 -0.001250  0.000479  0.000665 -0.000275   \n",
       "4    -0.004309 -0.002930 -0.001514 -0.001677  0.001152 -0.002061 -0.001539   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.003671 -0.010317 -0.005334 -0.001465 -0.005947  0.006385  0.004098   \n",
       "3729 -0.000519 -0.008743 -0.005130 -0.005704 -0.003289  0.008207  0.008556   \n",
       "3730 -0.030654 -0.002206 -0.030116 -0.025677  0.011747  0.001526  0.021477   \n",
       "3731 -0.012528 -0.000843 -0.015399 -0.009786  0.001590  0.005269  0.010376   \n",
       "3732 -0.024915 -0.003330 -0.022892 -0.008949  0.007582  0.009767  0.008863   \n",
       "\n",
       "           871       872       873       874       875       876       877  \\\n",
       "0     0.001370  0.000130  0.000944  0.001910  0.000543  0.014262  0.001064   \n",
       "1     0.001370  0.000130  0.000944  0.001910  0.000543  0.014262  0.001064   \n",
       "2     0.001370  0.000130  0.000944  0.001910  0.000543  0.014262  0.001064   \n",
       "3     0.001370  0.000130  0.000944  0.001910  0.000543  0.014262  0.001064   \n",
       "4     0.001802  0.001785 -0.000136 -0.001199 -0.000675  0.006114 -0.000320   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003143 -0.007337  0.003075 -0.008057 -0.005565 -0.060697 -0.003229   \n",
       "3729  0.003344 -0.010881 -0.007276 -0.008327 -0.007024 -0.068795 -0.005925   \n",
       "3730  0.001557 -0.040226 -0.019893 -0.002987 -0.009864 -0.154125 -0.011911   \n",
       "3731  0.001267 -0.010374 -0.009790 -0.005820 -0.006396 -0.088701 -0.009207   \n",
       "3732 -0.002902 -0.019668 -0.015461  0.000769 -0.009565 -0.094702 -0.012075   \n",
       "\n",
       "           878       879       880       881       882       883       884  \\\n",
       "0    -0.001312  0.000806 -0.000663 -0.001911 -0.000124 -0.002792  0.004730   \n",
       "1    -0.001312  0.000806 -0.000663 -0.001911 -0.000124 -0.002792  0.004730   \n",
       "2    -0.001312  0.000806 -0.000663 -0.001911 -0.000124 -0.002792  0.004730   \n",
       "3    -0.001312  0.000806 -0.000663 -0.001911 -0.000124 -0.002792  0.004730   \n",
       "4    -0.003560 -0.001729  0.005777 -0.000995 -0.001529  0.002345 -0.005559   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.006064 -0.003188  0.004351  0.000999 -0.003024  0.009441  0.004138   \n",
       "3729 -0.000610 -0.001817  0.000593  0.004546  0.000008  0.005683  0.003494   \n",
       "3730 -0.006457  0.005643 -0.018789 -0.013782  0.008661 -0.009733  0.013039   \n",
       "3731  0.000503 -0.000050 -0.009159 -0.009715 -0.002142  0.000194  0.004746   \n",
       "3732  0.002266  0.003600 -0.009056 -0.014292  0.003195  0.011806  0.011279   \n",
       "\n",
       "           885       886       887       888       889       890       891  \\\n",
       "0    -0.003076  0.002132  0.001743 -0.000668 -0.000627  0.003284 -0.001591   \n",
       "1    -0.003076  0.002132  0.001743 -0.000668 -0.000627  0.003284 -0.001591   \n",
       "2    -0.003076  0.002132  0.001743 -0.000668 -0.000627  0.003284 -0.001591   \n",
       "3    -0.003076  0.002132  0.001743 -0.000668 -0.000627  0.003284 -0.001591   \n",
       "4    -0.005697 -0.001107  0.001395 -0.002901 -0.000945  0.001950 -0.001399   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001603  0.004168 -0.001501 -0.002240 -0.002617 -0.007572 -0.004837   \n",
       "3729 -0.000549  0.003246  0.005530 -0.000742  0.006285 -0.005375 -0.002514   \n",
       "3730 -0.023416  0.002759  0.009994 -0.010633  0.022738  0.014133  0.013247   \n",
       "3731 -0.013538 -0.000488  0.010173 -0.003365  0.015203  0.008147  0.005277   \n",
       "3732 -0.013265 -0.002142  0.010131 -0.012343  0.022849  0.001692  0.007245   \n",
       "\n",
       "           892       893       894       895       896       897       898  \\\n",
       "0     0.003270 -0.001599 -0.002919  0.001687  0.003127 -0.001044  0.001535   \n",
       "1     0.003270 -0.001599 -0.002919  0.001687  0.003127 -0.001044  0.001535   \n",
       "2     0.003270 -0.001599 -0.002919  0.001687  0.003127 -0.001044  0.001535   \n",
       "3     0.003270 -0.001599 -0.002919  0.001687  0.003127 -0.001044  0.001535   \n",
       "4     0.000678 -0.000616 -0.005231  0.001189 -0.000142 -0.003779  0.001937   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002979  0.008550  0.007910 -0.008430 -0.009190 -0.015501 -0.007483   \n",
       "3729 -0.004900  0.010295 -0.000479 -0.011327 -0.008661 -0.017036 -0.009051   \n",
       "3730  0.002191  0.013585  0.000447  0.002308 -0.009974 -0.017590 -0.011969   \n",
       "3731  0.001525  0.009584 -0.003005 -0.005656 -0.002186 -0.014849 -0.005132   \n",
       "3732  0.003068  0.005600 -0.006456 -0.000256 -0.005433 -0.009549 -0.011748   \n",
       "\n",
       "           899       900       901       902       903       904       905  \\\n",
       "0    -0.001130  0.003034 -0.003500  0.002220 -0.001365  0.001214 -0.001045   \n",
       "1    -0.001130  0.003034 -0.003500  0.002220 -0.001365  0.001214 -0.001045   \n",
       "2    -0.001130  0.003034 -0.003500  0.002220 -0.001365  0.001214 -0.001045   \n",
       "3    -0.001130  0.003034 -0.003500  0.002220 -0.001365  0.001214 -0.001045   \n",
       "4     0.002254  0.000588  0.003431 -0.000333 -0.000748 -0.002627 -0.001062   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002947 -0.003342 -0.002443  0.011828  0.001698  0.011475  0.008131   \n",
       "3729 -0.004153 -0.002853  0.006036  0.013923  0.004335  0.012420  0.014307   \n",
       "3730 -0.001343 -0.006366 -0.022283  0.022161  0.010663  0.024728  0.020325   \n",
       "3731 -0.002130 -0.006065 -0.010093  0.014281  0.006598  0.013746  0.006167   \n",
       "3732 -0.001061 -0.003116 -0.014757  0.016029  0.007698  0.019931  0.017631   \n",
       "\n",
       "           906       907       908       909       910       911       912  \\\n",
       "0     0.001286 -0.000694  0.000340 -0.002049 -0.002644 -0.000833 -0.002612   \n",
       "1     0.001286 -0.000694  0.000340 -0.002049 -0.002644 -0.000833 -0.002612   \n",
       "2     0.001286 -0.000694  0.000340 -0.002049 -0.002644 -0.000833 -0.002612   \n",
       "3     0.001286 -0.000694  0.000340 -0.002049 -0.002644 -0.000833 -0.002612   \n",
       "4    -0.003581 -0.001945 -0.002319 -0.004213 -0.001675 -0.000043 -0.002564   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006325 -0.002210 -0.004297  0.005798  0.004262  0.012264 -0.006074   \n",
       "3729  0.009290 -0.002986  0.008898 -0.000420 -0.007552  0.009208 -0.005927   \n",
       "3730  0.020496 -0.017363  0.045114 -0.003959  0.004207  0.000816 -0.022021   \n",
       "3731  0.010814 -0.005055  0.020368  0.000943 -0.004726  0.004315 -0.008697   \n",
       "3732  0.016396 -0.010721  0.033958  0.000765 -0.002637 -0.008896 -0.012439   \n",
       "\n",
       "           913       914       915       916       917       918       919  \\\n",
       "0     0.000240  0.000381 -0.000718 -0.001947 -0.001996 -0.001519  0.001351   \n",
       "1     0.000240  0.000381 -0.000718 -0.001947 -0.001996 -0.001519  0.001351   \n",
       "2     0.000240  0.000381 -0.000718 -0.001947 -0.001996 -0.001519  0.001351   \n",
       "3     0.000240  0.000381 -0.000718 -0.001947 -0.001996 -0.001519  0.001351   \n",
       "4    -0.000704  0.004459  0.002380  0.001226 -0.003508 -0.002592  0.000043   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.003066  0.010232  0.005343  0.003184  0.000282  0.001695 -0.001385   \n",
       "3729 -0.000417  0.011064  0.000919 -0.001655 -0.005546  0.007039 -0.006975   \n",
       "3730 -0.000884  0.026293  0.000186 -0.002186 -0.001836  0.018321 -0.008159   \n",
       "3731 -0.001492  0.012311  0.006620 -0.003384 -0.000943  0.010286 -0.003920   \n",
       "3732 -0.007250  0.016043  0.012996 -0.004001  0.002799  0.017639 -0.008172   \n",
       "\n",
       "           920       921       922       923       924       925       926  \\\n",
       "0    -0.000675 -0.001213 -0.000648 -0.002192 -0.002354  0.004700  0.003405   \n",
       "1    -0.000675 -0.001213 -0.000648 -0.002192 -0.002354  0.004700  0.003405   \n",
       "2    -0.000675 -0.001213 -0.000648 -0.002192 -0.002354  0.004700  0.003405   \n",
       "3    -0.000675 -0.001213 -0.000648 -0.002192 -0.002354  0.004700  0.003405   \n",
       "4     0.003686 -0.000716 -0.003041 -0.003489 -0.007130  0.002390  0.009629   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004533 -0.004097  0.006333  0.005412 -0.005033 -0.007391 -0.005897   \n",
       "3729 -0.009629  0.000839  0.007111 -0.002052  0.002747 -0.006815  0.000017   \n",
       "3730  0.005986 -0.010864 -0.000798 -0.027278  0.018430  0.005589  0.026282   \n",
       "3731 -0.000030 -0.002571  0.002520 -0.015289  0.005796  0.009802  0.010031   \n",
       "3732  0.001751  0.002841 -0.003056 -0.023030  0.017053  0.013824  0.022626   \n",
       "\n",
       "           927       928       929       930       931       932       933  \\\n",
       "0    -0.002298  0.003752 -0.001438 -0.000931 -0.001868 -0.000715 -0.002735   \n",
       "1    -0.002298  0.003752 -0.001438 -0.000931 -0.001868 -0.000715 -0.002735   \n",
       "2    -0.002298  0.003752 -0.001438 -0.000931 -0.001868 -0.000715 -0.002735   \n",
       "3    -0.002298  0.003752 -0.001438 -0.000931 -0.001868 -0.000715 -0.002735   \n",
       "4    -0.000748  0.002511 -0.002080 -0.001481 -0.004387 -0.004540 -0.004378   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002225 -0.004812 -0.005262  0.012048 -0.005728 -0.007392 -0.008579   \n",
       "3729 -0.009508 -0.010007 -0.002760  0.007648 -0.007823 -0.003057 -0.016789   \n",
       "3730 -0.029662 -0.001365 -0.009846  0.015646 -0.024848 -0.014368 -0.019180   \n",
       "3731 -0.016055 -0.002525 -0.009154  0.009209 -0.015437 -0.007777 -0.012085   \n",
       "3732 -0.017240 -0.004917 -0.011054  0.009789 -0.020957 -0.008670 -0.017101   \n",
       "\n",
       "           934       935       936       937       938       939       940  \\\n",
       "0     0.002816  0.003794  0.001220 -0.003992  0.002243 -0.002790  0.003242   \n",
       "1     0.002816  0.003794  0.001220 -0.003992  0.002243 -0.002790  0.003242   \n",
       "2     0.002816  0.003794  0.001220 -0.003992  0.002243 -0.002790  0.003242   \n",
       "3     0.002816  0.003794  0.001220 -0.003992  0.002243 -0.002790  0.003242   \n",
       "4     0.003467  0.002943  0.000781  0.000123 -0.000622 -0.004561  0.002820   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006233 -0.005056  0.006742  0.005189  0.000417 -0.008313 -0.007317   \n",
       "3729  0.007013 -0.005265  0.017518  0.010508 -0.001850 -0.017382 -0.002990   \n",
       "3730  0.006436  0.022819  0.034319 -0.007180  0.006381 -0.039981  0.000517   \n",
       "3731  0.002940  0.006084  0.013671  0.000197  0.005658 -0.026751 -0.005343   \n",
       "3732  0.002761  0.005584  0.029840 -0.004997  0.009326 -0.029147  0.000692   \n",
       "\n",
       "           941       942       943       944       945       946       947  \\\n",
       "0     0.000895 -0.000943  0.000613 -0.001099 -0.000938  0.000435  0.001427   \n",
       "1     0.000895 -0.000943  0.000613 -0.001099 -0.000938  0.000435  0.001427   \n",
       "2     0.000895 -0.000943  0.000613 -0.001099 -0.000938  0.000435  0.001427   \n",
       "3     0.000895 -0.000943  0.000613 -0.001099 -0.000938  0.000435  0.001427   \n",
       "4     0.001108  0.004081  0.003653 -0.001278  0.000892 -0.000564 -0.000746   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006115  0.005129 -0.002841 -0.000614 -0.007128  0.011599  0.008932   \n",
       "3729  0.005662 -0.000709 -0.004809  0.001292 -0.002087  0.011112  0.009623   \n",
       "3730  0.015241  0.016596  0.018855  0.020741  0.007227  0.039614  0.023792   \n",
       "3731  0.007512  0.002361  0.003925  0.003020  0.003008  0.022163  0.012650   \n",
       "3732  0.010208  0.018566  0.006080  0.014835  0.001651  0.021805  0.017166   \n",
       "\n",
       "           948       949       950       951       952       953       954  \\\n",
       "0    -0.000020  0.003915 -0.003550 -0.002878 -0.000154  0.004259  0.002134   \n",
       "1    -0.000020  0.003915 -0.003550 -0.002878 -0.000154  0.004259  0.002134   \n",
       "2    -0.000020  0.003915 -0.003550 -0.002878 -0.000154  0.004259  0.002134   \n",
       "3    -0.000020  0.003915 -0.003550 -0.002878 -0.000154  0.004259  0.002134   \n",
       "4    -0.002499  0.003927  0.000692 -0.002960 -0.003541  0.001462  0.001089   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.011903  0.005094  0.000661  0.004745 -0.003011 -0.005974  0.007307   \n",
       "3729 -0.014576 -0.002806  0.001934  0.004828 -0.003330 -0.005601  0.004106   \n",
       "3730 -0.009778 -0.011070  0.001604  0.005568 -0.013704 -0.008019  0.007901   \n",
       "3731 -0.015703 -0.004107  0.005260  0.009882 -0.012031 -0.003147  0.004494   \n",
       "3732 -0.018237 -0.005385  0.001740  0.006459 -0.007206 -0.007421  0.001685   \n",
       "\n",
       "           955       956       957       958       959       960       961  \\\n",
       "0    -0.000896 -0.000822 -0.002914  0.000752 -0.001691 -0.001337  0.001714   \n",
       "1    -0.000896 -0.000822 -0.002914  0.000752 -0.001691 -0.001337  0.001714   \n",
       "2    -0.000896 -0.000822 -0.002914  0.000752 -0.001691 -0.001337  0.001714   \n",
       "3    -0.000896 -0.000822 -0.002914  0.000752 -0.001691 -0.001337  0.001714   \n",
       "4    -0.001346  0.002833 -0.002684 -0.001451  0.000939  0.002593 -0.003071   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001578 -0.008151  0.005671  0.004066 -0.006707 -0.002241 -0.006532   \n",
       "3729  0.007247 -0.009656  0.001263  0.002685 -0.003567 -0.002918 -0.008341   \n",
       "3730  0.013811  0.010576 -0.013372  0.004485  0.000714 -0.002843 -0.006731   \n",
       "3731  0.009656 -0.003146 -0.009368  0.000697 -0.002360 -0.000860 -0.001608   \n",
       "3732  0.012441  0.000132 -0.004736  0.000926  0.007850 -0.002772  0.002083   \n",
       "\n",
       "           962       963       964       965       966       967       968  \\\n",
       "0     0.003253  0.000719  0.001495  0.000057  0.002146  0.000377  0.000229   \n",
       "1     0.003253  0.000719  0.001495  0.000057  0.002146  0.000377  0.000229   \n",
       "2     0.003253  0.000719  0.001495  0.000057  0.002146  0.000377  0.000229   \n",
       "3     0.003253  0.000719  0.001495  0.000057  0.002146  0.000377  0.000229   \n",
       "4     0.001765 -0.000977  0.001575  0.000634  0.003121 -0.003025 -0.000148   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.004787  0.001448  0.002488 -0.000586 -0.003469 -0.004990  0.002304   \n",
       "3729  0.003936  0.001570 -0.002377 -0.000447 -0.007164 -0.005188  0.002694   \n",
       "3730 -0.007695 -0.000244  0.002664 -0.014306 -0.025652 -0.010265  0.018915   \n",
       "3731 -0.004402 -0.005496  0.003044 -0.008543 -0.010125  0.004312  0.010165   \n",
       "3732 -0.005950 -0.013209  0.002344 -0.014050 -0.026009 -0.002082  0.015065   \n",
       "\n",
       "           969       970       971       972       973       974       975  \\\n",
       "0    -0.001650 -0.002190  0.002390  0.000233 -0.000022 -0.000491  0.002442   \n",
       "1    -0.001650 -0.002190  0.002390  0.000233 -0.000022 -0.000491  0.002442   \n",
       "2    -0.001650 -0.002190  0.002390  0.000233 -0.000022 -0.000491  0.002442   \n",
       "3    -0.001650 -0.002190  0.002390  0.000233 -0.000022 -0.000491  0.002442   \n",
       "4    -0.001756 -0.001757  0.004334  0.001591  0.003742  0.002030  0.002391   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.009995 -0.011101  0.007077 -0.004715  0.007286 -0.002932 -0.000506   \n",
       "3729  0.003885 -0.015378  0.004355 -0.009257  0.013433 -0.006080  0.003559   \n",
       "3730  0.008392 -0.002735  0.009625 -0.000045  0.019280 -0.011543 -0.003635   \n",
       "3731  0.006160 -0.001559  0.009150 -0.006231  0.014016 -0.005033  0.004038   \n",
       "3732  0.000443 -0.004564  0.009337 -0.006233  0.015102 -0.003794 -0.005859   \n",
       "\n",
       "           976       977       978       979       980       981       982  \\\n",
       "0    -0.000788 -0.002966  0.000764 -0.001282  0.001701  0.001378  0.001369   \n",
       "1    -0.000788 -0.002966  0.000764 -0.001282  0.001701  0.001378  0.001369   \n",
       "2    -0.000788 -0.002966  0.000764 -0.001282  0.001701  0.001378  0.001369   \n",
       "3    -0.000788 -0.002966  0.000764 -0.001282  0.001701  0.001378  0.001369   \n",
       "4     0.002353 -0.003176  0.000200  0.001220 -0.004787  0.002628 -0.002720   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.009166  0.004778 -0.003077 -0.007048 -0.012998  0.007303 -0.008854   \n",
       "3729 -0.007016  0.002051 -0.002824 -0.004809 -0.006028  0.011708 -0.011090   \n",
       "3730 -0.009208 -0.002398  0.018267 -0.018103 -0.010019 -0.005060 -0.020002   \n",
       "3731 -0.005541  0.004458  0.004672 -0.008524 -0.000446  0.003886 -0.011758   \n",
       "3732 -0.014967 -0.007303  0.012076 -0.012833 -0.008719 -0.011926 -0.021319   \n",
       "\n",
       "           983       984       985       986       987       988       989  \\\n",
       "0    -0.000157 -0.001197 -0.000131  0.001362  0.001754 -0.000465 -0.002500   \n",
       "1    -0.000157 -0.001197 -0.000131  0.001362  0.001754 -0.000465 -0.002500   \n",
       "2    -0.000157 -0.001197 -0.000131  0.001362  0.001754 -0.000465 -0.002500   \n",
       "3    -0.000157 -0.001197 -0.000131  0.001362  0.001754 -0.000465 -0.002500   \n",
       "4     0.002225 -0.002864 -0.000322 -0.001335 -0.000826 -0.002364 -0.002668   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001154 -0.001642 -0.003245 -0.002352  0.002716  0.001694  0.002737   \n",
       "3729 -0.008606 -0.006414 -0.006267 -0.004676  0.008273  0.003542  0.007665   \n",
       "3730 -0.008267 -0.024416 -0.000172  0.005998  0.010427  0.020806 -0.019445   \n",
       "3731 -0.006797 -0.014141 -0.006321  0.001055  0.008618  0.008851  0.001085   \n",
       "3732 -0.007824 -0.010065 -0.005763  0.000566  0.007439  0.017264 -0.002576   \n",
       "\n",
       "           990       991       992       993       994       995       996  \\\n",
       "0     0.000516  0.000393  0.000094  0.001605  0.002362 -0.001563  0.001944   \n",
       "1     0.000516  0.000393  0.000094  0.001605  0.002362 -0.001563  0.001944   \n",
       "2     0.000516  0.000393  0.000094  0.001605  0.002362 -0.001563  0.001944   \n",
       "3     0.000516  0.000393  0.000094  0.001605  0.002362 -0.001563  0.001944   \n",
       "4     0.002826  0.003392 -0.004583  0.002345  0.003465 -0.000856 -0.001408   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006903 -0.025161  0.000656  0.005195 -0.002560  0.000402  0.003565   \n",
       "3729  0.006726 -0.025881 -0.003845  0.008888 -0.006632  0.003604  0.003729   \n",
       "3730  0.013879 -0.047675  0.014089  0.003904  0.011902 -0.011544  0.021045   \n",
       "3731  0.002576 -0.026481  0.003643 -0.000586 -0.004493 -0.002354  0.012792   \n",
       "3732  0.010836 -0.038802  0.002619 -0.002994 -0.002435 -0.005468  0.018599   \n",
       "\n",
       "           997       998       999      1000      1001      1002      1003  \\\n",
       "0     0.003385  0.001005 -0.001009  0.001133  0.000253  0.003299  0.000984   \n",
       "1     0.003385  0.001005 -0.001009  0.001133  0.000253  0.003299  0.000984   \n",
       "2     0.003385  0.001005 -0.001009  0.001133  0.000253  0.003299  0.000984   \n",
       "3     0.003385  0.001005 -0.001009  0.001133  0.000253  0.003299  0.000984   \n",
       "4     0.002822  0.001617 -0.001068  0.003910 -0.001384 -0.001121  0.000959   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.005294 -0.001042 -0.003891  0.001385 -0.005814 -0.002445  0.007236   \n",
       "3729 -0.005067  0.004900 -0.002961 -0.002708 -0.004938 -0.007445  0.011174   \n",
       "3730  0.005096  0.027078 -0.000786 -0.016242 -0.008748 -0.000880  0.009599   \n",
       "3731  0.004118  0.014548 -0.003366 -0.009376 -0.005777 -0.000153  0.008690   \n",
       "3732  0.005068  0.019546  0.001423 -0.017245 -0.006852  0.002107  0.011652   \n",
       "\n",
       "          1004      1005      1006      1007      1008      1009      1010  \\\n",
       "0     0.002715  0.002471 -0.000905  0.002816 -0.001033  0.001326  0.000456   \n",
       "1     0.002715  0.002471 -0.000905  0.002816 -0.001033  0.001326  0.000456   \n",
       "2     0.002715  0.002471 -0.000905  0.002816 -0.001033  0.001326  0.000456   \n",
       "3     0.002715  0.002471 -0.000905  0.002816 -0.001033  0.001326  0.000456   \n",
       "4     0.003791  0.000394  0.000678  0.004119  0.002529 -0.003827  0.001231   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005015 -0.009967 -0.000970  0.002171 -0.004240  0.003099  0.001778   \n",
       "3729  0.011634 -0.013013  0.000549  0.000415 -0.001292  0.002184 -0.002572   \n",
       "3730  0.025363 -0.006491  0.009129 -0.004410 -0.003317 -0.000640 -0.029610   \n",
       "3731  0.018885 -0.005637 -0.002932  0.002414  0.006981 -0.004953 -0.009645   \n",
       "3732  0.017299  0.001391  0.006992  0.002753  0.009885 -0.006471 -0.011566   \n",
       "\n",
       "          1011      1012      1013      1014      1015      1016      1017  \\\n",
       "0     0.001737 -0.001938  0.001141  0.000449  0.000199  0.003148  0.000627   \n",
       "1     0.001737 -0.001938  0.001141  0.000449  0.000199  0.003148  0.000627   \n",
       "2     0.001737 -0.001938  0.001141  0.000449  0.000199  0.003148  0.000627   \n",
       "3     0.001737 -0.001938  0.001141  0.000449  0.000199  0.003148  0.000627   \n",
       "4     0.000040 -0.001581 -0.003734  0.000321  0.000900  0.003138 -0.003122   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002112  0.001868  0.008177  0.009051  0.005942 -0.000101 -0.000157   \n",
       "3729 -0.005436  0.009482  0.010111  0.006133  0.009859 -0.003132 -0.007785   \n",
       "3730 -0.019390  0.030183  0.016225 -0.000228  0.012808 -0.005453  0.008847   \n",
       "3731 -0.007002  0.015099  0.003680  0.005166 -0.000422 -0.003926 -0.002706   \n",
       "3732 -0.012058  0.026382  0.000984  0.000227  0.002571 -0.004429  0.002642   \n",
       "\n",
       "          1018      1019      1020      1021      1022      1023      1024  \\\n",
       "0     0.006180 -0.000715 -0.003589 -0.001762 -0.000153 -0.002501 -0.000204   \n",
       "1     0.006180 -0.000715 -0.003589 -0.001762 -0.000153 -0.002501 -0.000204   \n",
       "2     0.006180 -0.000715 -0.003589 -0.001762 -0.000153 -0.002501 -0.000204   \n",
       "3     0.006180 -0.000715 -0.003589 -0.001762 -0.000153 -0.002501 -0.000204   \n",
       "4     0.006537 -0.001630 -0.005863  0.001435  0.001215 -0.002903 -0.001893   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.011027 -0.001329 -0.008444 -0.006795 -0.002029  0.006345 -0.010165   \n",
       "3729 -0.009636 -0.006097  0.005411 -0.007864  0.002982  0.009905 -0.019860   \n",
       "3730 -0.004736 -0.038601  0.008486 -0.003306 -0.010698  0.003705 -0.007405   \n",
       "3731 -0.006051 -0.018612  0.005620 -0.006797 -0.003928  0.003207 -0.011927   \n",
       "3732 -0.007165 -0.021826  0.013170  0.000623 -0.007792  0.010359 -0.012550   \n",
       "\n",
       "          1025      1026      1027      1028      1029      1030      1031  \\\n",
       "0    -0.000336  0.004184  0.001619  0.000964  0.002525 -0.000051 -0.001874   \n",
       "1    -0.000336  0.004184  0.001619  0.000964  0.002525 -0.000051 -0.001874   \n",
       "2    -0.000336  0.004184  0.001619  0.000964  0.002525 -0.000051 -0.001874   \n",
       "3    -0.000336  0.004184  0.001619  0.000964  0.002525 -0.000051 -0.001874   \n",
       "4     0.000994 -0.001149  0.003084  0.000570  0.002100 -0.001408 -0.003894   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.011244  0.003346  0.001837  0.000283 -0.004299 -0.008879 -0.005314   \n",
       "3729 -0.007794  0.003208 -0.001260  0.003031 -0.002514 -0.009475 -0.000774   \n",
       "3730 -0.005207  0.020073 -0.003011  0.002207 -0.020245  0.023561  0.001123   \n",
       "3731 -0.001529  0.009228  0.004600  0.007397 -0.005580  0.002534  0.003226   \n",
       "3732 -0.001098  0.010390 -0.003271  0.007058 -0.005854  0.017258  0.004966   \n",
       "\n",
       "          1032      1033      1034      1035      1036      1037      1038  \\\n",
       "0    -0.002089  0.000454  0.000840  0.002264 -0.000482  0.003808  0.000544   \n",
       "1    -0.002089  0.000454  0.000840  0.002264 -0.000482  0.003808  0.000544   \n",
       "2    -0.002089  0.000454  0.000840  0.002264 -0.000482  0.003808  0.000544   \n",
       "3    -0.002089  0.000454  0.000840  0.002264 -0.000482  0.003808  0.000544   \n",
       "4     0.002869 -0.001725 -0.000051  0.002778 -0.001366  0.000972 -0.002588   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005435  0.010013 -0.003408 -0.011762  0.003980  0.002708  0.011329   \n",
       "3729  0.000869  0.007110  0.006590 -0.014129  0.004374 -0.000771  0.014246   \n",
       "3730 -0.020889 -0.003368  0.020677 -0.001711  0.012416 -0.003048  0.030643   \n",
       "3731 -0.002794 -0.003271  0.010530 -0.012191  0.005421 -0.006576  0.020289   \n",
       "3732 -0.008088 -0.005937  0.008376 -0.019275  0.016451 -0.005743  0.029884   \n",
       "\n",
       "          1039      1040      1041      1042      1043      1044      1045  \\\n",
       "0     0.000362 -0.003832  0.000167 -0.003538  0.000675  0.000204  0.001931   \n",
       "1     0.000362 -0.003832  0.000167 -0.003538  0.000675  0.000204  0.001931   \n",
       "2     0.000362 -0.003832  0.000167 -0.003538  0.000675  0.000204  0.001931   \n",
       "3     0.000362 -0.003832  0.000167 -0.003538  0.000675  0.000204  0.001931   \n",
       "4     0.003184 -0.003577  0.002514 -0.000025  0.002339 -0.002745 -0.001510   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.006497 -0.009053  0.002202 -0.003057  0.007133  0.003445  0.004320   \n",
       "3729 -0.007978 -0.006759  0.003811  0.000280  0.003367 -0.002202  0.012182   \n",
       "3730  0.022871 -0.025569 -0.000883 -0.016898 -0.026108  0.001545  0.035452   \n",
       "3731  0.001385 -0.012464 -0.002598 -0.013499 -0.010528  0.000303  0.015255   \n",
       "3732 -0.002555 -0.022534  0.002689 -0.011871 -0.011311  0.002567  0.028535   \n",
       "\n",
       "          1046      1047      1048      1049      1050      1051      1052  \\\n",
       "0     0.000090 -0.001921 -0.001082  0.000738 -0.002090 -0.000141  0.004992   \n",
       "1     0.000090 -0.001921 -0.001082  0.000738 -0.002090 -0.000141  0.004992   \n",
       "2     0.000090 -0.001921 -0.001082  0.000738 -0.002090 -0.000141  0.004992   \n",
       "3     0.000090 -0.001921 -0.001082  0.000738 -0.002090 -0.000141  0.004992   \n",
       "4    -0.000468 -0.000951 -0.001991  0.001048 -0.006184 -0.003255  0.001149   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002970  0.003383 -0.003527  0.003751 -0.003493 -0.000049 -0.001987   \n",
       "3729 -0.000320  0.005160 -0.005933  0.007894 -0.008928  0.002553 -0.002347   \n",
       "3730  0.007199  0.014202  0.004084  0.011967 -0.016386 -0.007885 -0.008022   \n",
       "3731  0.006967  0.006894 -0.000435 -0.000263 -0.009127 -0.001394 -0.000798   \n",
       "3732  0.006446  0.007631 -0.001049  0.013509 -0.014306  0.003409 -0.005613   \n",
       "\n",
       "          1053      1054      1055      1056      1057      1058      1059  \\\n",
       "0     0.002439 -0.000099  0.001142  0.003668  0.001605  0.001739 -0.000944   \n",
       "1     0.002439 -0.000099  0.001142  0.003668  0.001605  0.001739 -0.000944   \n",
       "2     0.002439 -0.000099  0.001142  0.003668  0.001605  0.001739 -0.000944   \n",
       "3     0.002439 -0.000099  0.001142  0.003668  0.001605  0.001739 -0.000944   \n",
       "4     0.001580 -0.000978  0.002539  0.002319  0.001807  0.004494 -0.001323   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000017 -0.005411  0.006548  0.008914  0.000638 -0.012132 -0.004102   \n",
       "3729 -0.002496  0.002480  0.008737  0.007237 -0.002151 -0.016620 -0.011320   \n",
       "3730 -0.009594  0.020564  0.013528  0.022065 -0.008168 -0.006749 -0.021773   \n",
       "3731 -0.003185  0.008904  0.009782  0.010733 -0.002061 -0.006484 -0.014428   \n",
       "3732  0.006671  0.010732  0.004710  0.018928 -0.007619 -0.002958 -0.016103   \n",
       "\n",
       "          1060      1061      1062      1063      1064      1065      1066  \\\n",
       "0     0.001349 -0.000763  0.000259  0.002354  0.001217 -0.004476  0.000971   \n",
       "1     0.001349 -0.000763  0.000259  0.002354  0.001217 -0.004476  0.000971   \n",
       "2     0.001349 -0.000763  0.000259  0.002354  0.001217 -0.004476  0.000971   \n",
       "3     0.001349 -0.000763  0.000259  0.002354  0.001217 -0.004476  0.000971   \n",
       "4    -0.001876  0.004461 -0.001555  0.004490 -0.003628 -0.002959  0.001206   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000943 -0.012850 -0.000442 -0.003732 -0.000119 -0.012227  0.004068   \n",
       "3729 -0.002980 -0.012777 -0.004446 -0.006885 -0.000166 -0.014283 -0.001430   \n",
       "3730 -0.006047 -0.024044  0.002758  0.007579 -0.008568 -0.023402  0.008505   \n",
       "3731 -0.004167 -0.017179  0.000279 -0.000022  0.001980 -0.013288  0.000520   \n",
       "3732 -0.000340 -0.015794  0.002108  0.002423 -0.004922 -0.016649  0.004355   \n",
       "\n",
       "          1067      1068      1069      1070      1071      1072      1073  \\\n",
       "0     0.005677  0.000478 -0.000240  0.000732  0.001317 -0.003606 -0.004056   \n",
       "1     0.005677  0.000478 -0.000240  0.000732  0.001317 -0.003606 -0.004056   \n",
       "2     0.005677  0.000478 -0.000240  0.000732  0.001317 -0.003606 -0.004056   \n",
       "3     0.005677  0.000478 -0.000240  0.000732  0.001317 -0.003606 -0.004056   \n",
       "4     0.007836  0.003840  0.002200 -0.008127 -0.001971  0.001895 -0.004661   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001276  0.000127 -0.001520  0.000678 -0.002492 -0.000337  0.014066   \n",
       "3729 -0.004362 -0.007093 -0.003423 -0.000585 -0.003912  0.002895  0.009398   \n",
       "3730 -0.020307 -0.027540 -0.006865  0.007365  0.001497  0.003977  0.006416   \n",
       "3731 -0.000579 -0.016572 -0.008174 -0.000980  0.003738  0.004582  0.009048   \n",
       "3732 -0.011956 -0.018321 -0.004920 -0.006050  0.007201  0.001968  0.003428   \n",
       "\n",
       "          1074      1075      1076      1077      1078      1079      1080  \\\n",
       "0    -0.000326  0.001430  0.002503  0.000671 -0.002191  0.003219  0.003096   \n",
       "1    -0.000326  0.001430  0.002503  0.000671 -0.002191  0.003219  0.003096   \n",
       "2    -0.000326  0.001430  0.002503  0.000671 -0.002191  0.003219  0.003096   \n",
       "3    -0.000326  0.001430  0.002503  0.000671 -0.002191  0.003219  0.003096   \n",
       "4    -0.001670  0.001771  0.000963  0.002267 -0.001661  0.005597  0.004580   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.014473 -0.003179  0.002331  0.005427  0.005804 -0.007106  0.004689   \n",
       "3729  0.018771 -0.001434  0.010499  0.006657  0.007827 -0.006293  0.002736   \n",
       "3730  0.007345  0.004731 -0.007601  0.000043  0.013511 -0.033343  0.009630   \n",
       "3731  0.011027  0.002674  0.009972  0.001004  0.004819 -0.006912  0.001470   \n",
       "3732  0.008941  0.005601  0.007466  0.000877  0.005762 -0.022181  0.000850   \n",
       "\n",
       "          1081      1082      1083      1084      1085      1086      1087  \\\n",
       "0     0.003174 -0.003121 -0.003061 -0.001855  0.003509  0.000144  0.000375   \n",
       "1     0.003174 -0.003121 -0.003061 -0.001855  0.003509  0.000144  0.000375   \n",
       "2     0.003174 -0.003121 -0.003061 -0.001855  0.003509  0.000144  0.000375   \n",
       "3     0.003174 -0.003121 -0.003061 -0.001855  0.003509  0.000144  0.000375   \n",
       "4     0.002309 -0.002515 -0.001431  0.001854  0.000177 -0.000519  0.003373   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004587  0.003233  0.000664  0.003754 -0.000662 -0.010687 -0.006939   \n",
       "3729 -0.003865  0.002184 -0.000697  0.006873 -0.003146 -0.011896 -0.009033   \n",
       "3730  0.002584  0.009188 -0.006700 -0.008150  0.028051 -0.002849  0.011607   \n",
       "3731  0.007051  0.005858 -0.001069  0.000239  0.011767 -0.009489  0.002333   \n",
       "3732  0.010818  0.011421 -0.002909 -0.006016  0.016933 -0.001340  0.008422   \n",
       "\n",
       "          1088      1089      1090      1091      1092      1093      1094  \\\n",
       "0    -0.001343 -0.000947  0.000456 -0.002994 -0.002928 -0.002762  0.001194   \n",
       "1    -0.001343 -0.000947  0.000456 -0.002994 -0.002928 -0.002762  0.001194   \n",
       "2    -0.001343 -0.000947  0.000456 -0.002994 -0.002928 -0.002762  0.001194   \n",
       "3    -0.001343 -0.000947  0.000456 -0.002994 -0.002928 -0.002762  0.001194   \n",
       "4    -0.002627 -0.000545  0.000461  0.000832  0.000509 -0.001902  0.002832   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001018  0.001963  0.001727  0.004623  0.008472  0.010430  0.003693   \n",
       "3729  0.000527  0.001116  0.010508  0.004524 -0.001260  0.007194  0.008208   \n",
       "3730 -0.000309  0.010972  0.000937 -0.006244 -0.003250 -0.005940  0.019554   \n",
       "3731 -0.003820  0.004696  0.008407 -0.001527 -0.003784  0.001245  0.014570   \n",
       "3732  0.006179  0.005942  0.007918  0.004389  0.003493 -0.006422  0.015105   \n",
       "\n",
       "          1095      1096      1097      1098      1099      1100      1101  \\\n",
       "0    -0.007311 -0.000554 -0.002575  0.000468 -0.001537 -0.002586 -0.001885   \n",
       "1    -0.007311 -0.000554 -0.002575  0.000468 -0.001537 -0.002586 -0.001885   \n",
       "2    -0.007311 -0.000554 -0.002575  0.000468 -0.001537 -0.002586 -0.001885   \n",
       "3    -0.007311 -0.000554 -0.002575  0.000468 -0.001537 -0.002586 -0.001885   \n",
       "4    -0.012076 -0.002398 -0.001357  0.003764 -0.003074  0.001152  0.001437   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.008233  0.002822  0.000969  0.001984 -0.001801 -0.001586  0.006529   \n",
       "3729 -0.000464  0.002797  0.000914  0.005278  0.000875  0.001244  0.004376   \n",
       "3730 -0.005578  0.014283  0.000266 -0.003224 -0.005682 -0.008623  0.021773   \n",
       "3731  0.001162  0.006262 -0.002427  0.006345 -0.001294 -0.007161  0.004874   \n",
       "3732 -0.002515  0.005103 -0.001516 -0.004213 -0.002045 -0.005396  0.013854   \n",
       "\n",
       "          1102      1103      1104      1105      1106      1107      1108  \\\n",
       "0     0.000400 -0.003383  0.000782 -0.000970 -0.001865 -0.004904  0.002138   \n",
       "1     0.000400 -0.003383  0.000782 -0.000970 -0.001865 -0.004904  0.002138   \n",
       "2     0.000400 -0.003383  0.000782 -0.000970 -0.001865 -0.004904  0.002138   \n",
       "3     0.000400 -0.003383  0.000782 -0.000970 -0.001865 -0.004904  0.002138   \n",
       "4    -0.004604 -0.008560 -0.000431  0.003072  0.000611 -0.002300 -0.000336   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002727  0.001704  0.000540 -0.001175  0.005885 -0.003644 -0.008909   \n",
       "3729  0.004129 -0.002325  0.005264 -0.001337  0.001572 -0.007667 -0.007800   \n",
       "3730  0.031220 -0.029689  0.023308  0.002432  0.006262 -0.039200  0.002349   \n",
       "3731  0.011655 -0.017056  0.013075 -0.000128  0.006975 -0.017353 -0.002095   \n",
       "3732  0.018427 -0.018106  0.007019 -0.000176  0.012725 -0.027523  0.009397   \n",
       "\n",
       "          1109      1110      1111      1112      1113      1114      1115  \\\n",
       "0    -0.000328 -0.002694  0.000921 -0.000662 -0.004249 -0.000482  0.001905   \n",
       "1    -0.000328 -0.002694  0.000921 -0.000662 -0.004249 -0.000482  0.001905   \n",
       "2    -0.000328 -0.002694  0.000921 -0.000662 -0.004249 -0.000482  0.001905   \n",
       "3    -0.000328 -0.002694  0.000921 -0.000662 -0.004249 -0.000482  0.001905   \n",
       "4    -0.002116 -0.003475  0.002823 -0.001878 -0.003580 -0.001365 -0.001170   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000958  0.004460  0.001717 -0.001592 -0.006151 -0.010675  0.002133   \n",
       "3729  0.000142  0.007494  0.001671 -0.003127 -0.004707 -0.015679  0.009976   \n",
       "3730 -0.014457  0.004031  0.020708  0.001869  0.000809  0.001819 -0.011128   \n",
       "3731 -0.002069 -0.000820  0.014051 -0.000180 -0.005497 -0.005318 -0.000449   \n",
       "3732 -0.007261 -0.001136  0.017389  0.003879 -0.004570 -0.009426 -0.006834   \n",
       "\n",
       "          1116      1117      1118      1119      1120      1121      1122  \\\n",
       "0    -0.001651  0.001290  0.002213  0.000362 -0.002842 -0.001707 -0.000085   \n",
       "1    -0.001651  0.001290  0.002213  0.000362 -0.002842 -0.001707 -0.000085   \n",
       "2    -0.001651  0.001290  0.002213  0.000362 -0.002842 -0.001707 -0.000085   \n",
       "3    -0.001651  0.001290  0.002213  0.000362 -0.002842 -0.001707 -0.000085   \n",
       "4    -0.000118  0.005157  0.000972  0.001106  0.000956 -0.004654  0.003154   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001019 -0.002263 -0.000294  0.003619  0.009191  0.001704  0.001547   \n",
       "3729 -0.002012 -0.012222  0.003934  0.004790 -0.000455  0.006099  0.001023   \n",
       "3730 -0.015858  0.029997 -0.015667 -0.023602  0.003477 -0.016809 -0.020017   \n",
       "3731 -0.002904  0.005947 -0.000998 -0.007633  0.003197 -0.004947 -0.005357   \n",
       "3732 -0.002359  0.004422 -0.012310 -0.016625  0.000746 -0.007278 -0.013717   \n",
       "\n",
       "          1123      1124      1125      1126      1127      1128      1129  \\\n",
       "0    -0.000421  0.004339  0.000256 -0.001116 -0.000351 -0.001625  0.002542   \n",
       "1    -0.000421  0.004339  0.000256 -0.001116 -0.000351 -0.001625  0.002542   \n",
       "2    -0.000421  0.004339  0.000256 -0.001116 -0.000351 -0.001625  0.002542   \n",
       "3    -0.000421  0.004339  0.000256 -0.001116 -0.000351 -0.001625  0.002542   \n",
       "4    -0.003350  0.005813 -0.002700 -0.002209 -0.000312  0.000338 -0.000386   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.003768 -0.011128 -0.009417 -0.006439  0.007931 -0.000818 -0.005343   \n",
       "3729 -0.009908 -0.002091 -0.006309 -0.005768  0.009680 -0.001691 -0.003182   \n",
       "3730 -0.015200  0.016012  0.005536  0.005711  0.000073  0.016810 -0.004948   \n",
       "3731 -0.002378  0.000204  0.001602 -0.000427  0.003871  0.011190 -0.000533   \n",
       "3732 -0.009700  0.007763  0.011673  0.008404  0.003669  0.012282 -0.007833   \n",
       "\n",
       "          1130      1131      1132      1133      1134      1135      1136  \\\n",
       "0    -0.003126 -0.003200 -0.001840  0.002916 -0.000262  0.000590 -0.001361   \n",
       "1    -0.003126 -0.003200 -0.001840  0.002916 -0.000262  0.000590 -0.001361   \n",
       "2    -0.003126 -0.003200 -0.001840  0.002916 -0.000262  0.000590 -0.001361   \n",
       "3    -0.003126 -0.003200 -0.001840  0.002916 -0.000262  0.000590 -0.001361   \n",
       "4    -0.003230 -0.001570 -0.000964  0.000624 -0.003470 -0.000590  0.000294   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.008997  0.003909  0.001425 -0.002152 -0.008057  0.014025  0.003022   \n",
       "3729 -0.003315  0.001719 -0.007472  0.003637 -0.007083  0.013013  0.005446   \n",
       "3730 -0.016748 -0.015596 -0.009684  0.015252 -0.012349  0.022288  0.016832   \n",
       "3731 -0.008234 -0.001427 -0.007397  0.009120 -0.003209  0.013885  0.013373   \n",
       "3732 -0.007332 -0.009415 -0.013022  0.016509 -0.007579  0.018860  0.015885   \n",
       "\n",
       "          1137      1138      1139      1140      1141      1142      1143  \\\n",
       "0    -0.000722 -0.000840  0.000951 -0.002294 -0.002051 -0.000354 -0.001136   \n",
       "1    -0.000722 -0.000840  0.000951 -0.002294 -0.002051 -0.000354 -0.001136   \n",
       "2    -0.000722 -0.000840  0.000951 -0.002294 -0.002051 -0.000354 -0.001136   \n",
       "3    -0.000722 -0.000840  0.000951 -0.002294 -0.002051 -0.000354 -0.001136   \n",
       "4     0.000471 -0.006606  0.002334 -0.004957 -0.003944 -0.000618  0.006567   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.009233 -0.001361 -0.000651  0.000772 -0.003992 -0.014725 -0.000488   \n",
       "3729 -0.007456 -0.005139  0.005355 -0.004075 -0.000034 -0.012683  0.003566   \n",
       "3730  0.005122 -0.019801 -0.001751 -0.019505  0.013162 -0.018780  0.005117   \n",
       "3731  0.004734 -0.015384  0.000503 -0.010901  0.007405 -0.013878  0.010089   \n",
       "3732  0.007835 -0.014896  0.013266 -0.011979  0.011239 -0.012270 -0.000306   \n",
       "\n",
       "          1144      1145      1146      1147      1148      1149      1150  \\\n",
       "0    -0.004360 -0.000841  0.001889 -0.000004  0.003308  0.003617 -0.004148   \n",
       "1    -0.004360 -0.000841  0.001889 -0.000004  0.003308  0.003617 -0.004148   \n",
       "2    -0.004360 -0.000841  0.001889 -0.000004  0.003308  0.003617 -0.004148   \n",
       "3    -0.004360 -0.000841  0.001889 -0.000004  0.003308  0.003617 -0.004148   \n",
       "4    -0.000768  0.000450  0.001868 -0.000383  0.003435  0.003918  0.000992   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.006974  0.006879  0.003609 -0.003564 -0.006680 -0.010997  0.007559   \n",
       "3729  0.013803  0.005446  0.004989 -0.000803 -0.001880 -0.016915  0.000036   \n",
       "3730  0.001795  0.000247 -0.024610 -0.014850 -0.000526 -0.024633 -0.005404   \n",
       "3731  0.007520  0.004323 -0.007298 -0.007975  0.003294 -0.014838 -0.004809   \n",
       "3732  0.006109  0.007002 -0.014082 -0.009283 -0.003032 -0.015690 -0.002476   \n",
       "\n",
       "          1151      1152      1153      1154      1155      1156      1157  \\\n",
       "0     0.003030 -0.002511 -0.004899 -0.000284 -0.004649  0.001188 -0.003483   \n",
       "1     0.003030 -0.002511 -0.004899 -0.000284 -0.004649  0.001188 -0.003483   \n",
       "2     0.003030 -0.002511 -0.004899 -0.000284 -0.004649  0.001188 -0.003483   \n",
       "3     0.003030 -0.002511 -0.004899 -0.000284 -0.004649  0.001188 -0.003483   \n",
       "4     0.000512 -0.003230 -0.003286 -0.002618 -0.000408  0.000934  0.001948   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.010159 -0.014733 -0.005178 -0.002334  0.002530 -0.004719  0.007352   \n",
       "3729  0.016125 -0.006308 -0.011811 -0.003524  0.004091 -0.003922  0.010138   \n",
       "3730  0.011717  0.013935 -0.018046  0.022030  0.001604 -0.011239  0.014247   \n",
       "3731  0.013251  0.002273 -0.013875  0.012669  0.002175 -0.005167  0.008062   \n",
       "3732  0.009485  0.013930 -0.016383  0.016043  0.003408 -0.009370  0.012278   \n",
       "\n",
       "          1158      1159      1160      1161      1162      1163      1164  \\\n",
       "0     0.003035  0.000596  0.013246  0.003318 -0.001301 -0.001465 -0.000627   \n",
       "1     0.003035  0.000596  0.013246  0.003318 -0.001301 -0.001465 -0.000627   \n",
       "2     0.003035  0.000596  0.013246  0.003318 -0.001301 -0.001465 -0.000627   \n",
       "3     0.003035  0.000596  0.013246  0.003318 -0.001301 -0.001465 -0.000627   \n",
       "4    -0.002655  0.002592  0.040950 -0.000443 -0.003214 -0.000818  0.001212   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.001532  0.001519  0.047338  0.007391 -0.002663  0.000920 -0.004650   \n",
       "3729 -0.000400 -0.000627  0.018082  0.006937 -0.004846  0.012710 -0.008887   \n",
       "3730  0.001578  0.021865  0.026658  0.008097  0.011861  0.023083 -0.033469   \n",
       "3731  0.001263  0.012151  0.008454  0.001987  0.004420  0.013856 -0.015964   \n",
       "3732  0.004710  0.017376  0.015070 -0.004606  0.009077  0.021997 -0.020869   \n",
       "\n",
       "          1165      1166      1167      1168      1169      1170      1171  \\\n",
       "0    -0.004009  0.000236 -0.001361  0.000791  0.000537  0.001320  0.000450   \n",
       "1    -0.004009  0.000236 -0.001361  0.000791  0.000537  0.001320  0.000450   \n",
       "2    -0.004009  0.000236 -0.001361  0.000791  0.000537  0.001320  0.000450   \n",
       "3    -0.004009  0.000236 -0.001361  0.000791  0.000537  0.001320  0.000450   \n",
       "4    -0.006284 -0.001470  0.000137  0.002616  0.003876  0.004097  0.001317   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005127  0.005086 -0.002160  0.000678  0.002952 -0.003636 -0.013328   \n",
       "3729  0.004896  0.001713 -0.001927  0.009542  0.007249  0.003211 -0.013045   \n",
       "3730 -0.012333 -0.009827  0.003996  0.029743  0.015632 -0.017103 -0.013163   \n",
       "3731 -0.004239 -0.000673  0.001831  0.012577  0.008599 -0.010648 -0.012607   \n",
       "3732 -0.009772 -0.008514 -0.004545  0.019639  0.010824 -0.012849 -0.011415   \n",
       "\n",
       "          1172      1173      1174      1175      1176      1177      1178  \\\n",
       "0     0.001044 -0.001955  0.002220 -0.001010  0.001541 -0.001902  0.004486   \n",
       "1     0.001044 -0.001955  0.002220 -0.001010  0.001541 -0.001902  0.004486   \n",
       "2     0.001044 -0.001955  0.002220 -0.001010  0.001541 -0.001902  0.004486   \n",
       "3     0.001044 -0.001955  0.002220 -0.001010  0.001541 -0.001902  0.004486   \n",
       "4     0.001836 -0.001845  0.001931 -0.000116 -0.000225 -0.006748  0.001570   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.007709  0.004569 -0.002575 -0.000972 -0.002029  0.003153  0.002792   \n",
       "3729 -0.008204  0.000922 -0.004485 -0.006290 -0.006257 -0.002593  0.002016   \n",
       "3730  0.007960 -0.005243 -0.002643 -0.030101 -0.011409 -0.034739  0.022576   \n",
       "3731  0.003760 -0.004256 -0.007629 -0.017924 -0.010815 -0.019907  0.012008   \n",
       "3732  0.002991 -0.010763 -0.015348 -0.030125 -0.004401 -0.026870  0.021142   \n",
       "\n",
       "          1179      1180      1181      1182      1183      1184      1185  \\\n",
       "0    -0.002665  0.006165 -0.002304  0.000868 -0.002610  0.001956  0.001153   \n",
       "1    -0.002665  0.006165 -0.002304  0.000868 -0.002610  0.001956  0.001153   \n",
       "2    -0.002665  0.006165 -0.002304  0.000868 -0.002610  0.001956  0.001153   \n",
       "3    -0.002665  0.006165 -0.002304  0.000868 -0.002610  0.001956  0.001153   \n",
       "4    -0.000964  0.003761 -0.001942  0.003567  0.000604  0.006583  0.003598   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.016595  0.002479 -0.004988 -0.003415  0.013394 -0.006537  0.009334   \n",
       "3729 -0.011472  0.000027 -0.009606  0.004269  0.012041 -0.007846  0.003630   \n",
       "3730 -0.028650 -0.001897 -0.028103  0.000033  0.022006 -0.034320  0.023572   \n",
       "3731 -0.008528 -0.000311 -0.012759  0.007218  0.013702 -0.009488  0.015019   \n",
       "3732 -0.011081 -0.005970 -0.020063  0.008371  0.017486 -0.016539  0.015583   \n",
       "\n",
       "          1186      1187      1188      1189      1190      1191      1192  \\\n",
       "0     0.002845 -0.002574  0.001107 -0.001770  0.001352 -0.002373 -0.003131   \n",
       "1     0.002845 -0.002574  0.001107 -0.001770  0.001352 -0.002373 -0.003131   \n",
       "2     0.002845 -0.002574  0.001107 -0.001770  0.001352 -0.002373 -0.003131   \n",
       "3     0.002845 -0.002574  0.001107 -0.001770  0.001352 -0.002373 -0.003131   \n",
       "4     0.004804 -0.002028 -0.000399 -0.000335  0.000534 -0.002704 -0.003500   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000333 -0.006531 -0.000129 -0.007381  0.003210  0.000904  0.002817   \n",
       "3729  0.001794  0.000750 -0.001138 -0.006959  0.009960  0.002981  0.000268   \n",
       "3730  0.026788  0.012450 -0.017769  0.006946  0.013706 -0.001218 -0.015515   \n",
       "3731  0.008593  0.002801 -0.009177  0.002372  0.007718 -0.002499 -0.001699   \n",
       "3732  0.017362  0.017482 -0.013634  0.009486  0.007944 -0.005911 -0.010120   \n",
       "\n",
       "          1193      1194      1195      1196      1197      1198      1199  \\\n",
       "0    -0.000198 -0.002885  0.002568 -0.002225  0.000261  0.000731  0.001686   \n",
       "1    -0.000198 -0.002885  0.002568 -0.002225  0.000261  0.000731  0.001686   \n",
       "2    -0.000198 -0.002885  0.002568 -0.002225  0.000261  0.000731  0.001686   \n",
       "3    -0.000198 -0.002885  0.002568 -0.002225  0.000261  0.000731  0.001686   \n",
       "4     0.000399 -0.002102  0.003298  0.000281 -0.002991  0.000926  0.003559   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000622  0.000173  0.011426 -0.003281  0.000395 -0.004874 -0.006136   \n",
       "3729  0.002521  0.002553  0.013006  0.006775 -0.001098 -0.001367 -0.004380   \n",
       "3730  0.020259  0.009028  0.010207 -0.021500  0.010486 -0.000034  0.014982   \n",
       "3731  0.010950  0.005768  0.012455 -0.011750  0.000152 -0.001383  0.001503   \n",
       "3732  0.017313  0.003824  0.016970 -0.002640  0.005406 -0.001158  0.007805   \n",
       "\n",
       "          1200      1201      1202      1203      1204      1205      1206  \\\n",
       "0    -0.001446  0.001312  0.001972 -0.000159  0.002543 -0.000479 -0.002388   \n",
       "1    -0.001446  0.001312  0.001972 -0.000159  0.002543 -0.000479 -0.002388   \n",
       "2    -0.001446  0.001312  0.001972 -0.000159  0.002543 -0.000479 -0.002388   \n",
       "3    -0.001446  0.001312  0.001972 -0.000159  0.002543 -0.000479 -0.002388   \n",
       "4    -0.004123 -0.003602  0.002504  0.001226  0.003692 -0.003883 -0.002092   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.009547  0.008051 -0.001626  0.003418 -0.000933  0.003483 -0.010502   \n",
       "3729  0.007726  0.007090  0.003558  0.001523 -0.007091  0.004461 -0.012395   \n",
       "3730 -0.002508 -0.006881 -0.003400  0.006935 -0.001289  0.010740  0.001525   \n",
       "3731  0.000125  0.002739  0.003896  0.002257  0.000117  0.001191  0.001902   \n",
       "3732 -0.007749 -0.001430  0.001831  0.009916 -0.002302 -0.001810  0.003421   \n",
       "\n",
       "          1207      1208      1209      1210      1211      1212      1213  \\\n",
       "0     0.000377 -0.000414 -0.001825  0.000848 -0.001172 -0.000149 -0.002991   \n",
       "1     0.000377 -0.000414 -0.001825  0.000848 -0.001172 -0.000149 -0.002991   \n",
       "2     0.000377 -0.000414 -0.001825  0.000848 -0.001172 -0.000149 -0.002991   \n",
       "3     0.000377 -0.000414 -0.001825  0.000848 -0.001172 -0.000149 -0.002991   \n",
       "4    -0.000666  0.002744  0.004849  0.002138 -0.002244 -0.002683 -0.003866   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.002214  0.000709 -0.005218 -0.002550  0.004289 -0.004681  0.008191   \n",
       "3729 -0.003454  0.001532 -0.000480  0.001032 -0.001172 -0.006051  0.008702   \n",
       "3730 -0.002616  0.002032  0.006760 -0.002962  0.013703 -0.014754  0.021360   \n",
       "3731  0.002014  0.011581  0.003535 -0.001087  0.008272 -0.008000  0.013401   \n",
       "3732 -0.000026  0.007665  0.006362 -0.000269  0.013439 -0.009226  0.018706   \n",
       "\n",
       "          1214      1215      1216      1217      1218      1219      1220  \\\n",
       "0    -0.002600  0.002683 -0.000656  0.004757  0.000422  0.003060 -0.001358   \n",
       "1    -0.002600  0.002683 -0.000656  0.004757  0.000422  0.003060 -0.001358   \n",
       "2    -0.002600  0.002683 -0.000656  0.004757  0.000422  0.003060 -0.001358   \n",
       "3    -0.002600  0.002683 -0.000656  0.004757  0.000422  0.003060 -0.001358   \n",
       "4    -0.000683 -0.002593  0.000698 -0.001432  0.005750  0.005302 -0.001213   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.000144  0.005022 -0.001442 -0.001293  0.004816 -0.006809  0.009081   \n",
       "3729  0.006095  0.007814  0.001380  0.001218  0.006733 -0.006362  0.012209   \n",
       "3730  0.013718  0.039999  0.004008  0.005189  0.029875  0.016394  0.015664   \n",
       "3731  0.011201  0.017522  0.004555  0.005950  0.012293  0.007061  0.015052   \n",
       "3732  0.009456  0.029043  0.005632  0.010316  0.015829  0.017358  0.013094   \n",
       "\n",
       "          1221      1222      1223      1224      1225      1226      1227  \\\n",
       "0    -0.001585 -0.003439  0.001919 -0.001025  0.001760  0.001856  0.000632   \n",
       "1    -0.001585 -0.003439  0.001919 -0.001025  0.001760  0.001856  0.000632   \n",
       "2    -0.001585 -0.003439  0.001919 -0.001025  0.001760  0.001856  0.000632   \n",
       "3    -0.001585 -0.003439  0.001919 -0.001025  0.001760  0.001856  0.000632   \n",
       "4    -0.003496 -0.001186  0.002421  0.004703 -0.000921 -0.005373  0.001327   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.000935  0.010252  0.009133 -0.004256  0.003006 -0.009026 -0.006350   \n",
       "3729 -0.000682  0.005983  0.009106 -0.008967 -0.002079 -0.006080 -0.002309   \n",
       "3730  0.024258 -0.004852  0.003751 -0.009283 -0.021068 -0.039508  0.014124   \n",
       "3731  0.005686 -0.004272 -0.002284 -0.008144 -0.006011 -0.013858  0.007633   \n",
       "3732  0.011203  0.002598 -0.001974 -0.003581 -0.003643 -0.013625  0.016447   \n",
       "\n",
       "          1228      1229      1230      1231      1232      1233      1234  \\\n",
       "0    -0.002373 -0.002567  0.002947  0.000547  0.000015  0.001571  0.000081   \n",
       "1    -0.002373 -0.002567  0.002947  0.000547  0.000015  0.001571  0.000081   \n",
       "2    -0.002373 -0.002567  0.002947  0.000547  0.000015  0.001571  0.000081   \n",
       "3    -0.002373 -0.002567  0.002947  0.000547  0.000015  0.001571  0.000081   \n",
       "4    -0.001848 -0.001792  0.000617 -0.002689 -0.000543  0.000536 -0.000006   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001395  0.006454  0.007711 -0.001591  0.016419 -0.001153  0.005786   \n",
       "3729  0.005296  0.012864  0.010769 -0.001154  0.013791  0.000803 -0.001929   \n",
       "3730  0.014023 -0.003695  0.019858 -0.008319  0.004834  0.012843 -0.003913   \n",
       "3731  0.006829  0.002105  0.013005 -0.004089  0.000854  0.002546 -0.000919   \n",
       "3732  0.006203  0.011155  0.011566  0.001913  0.002399  0.010810 -0.003206   \n",
       "\n",
       "          1235      1236      1237      1238      1239      1240      1241  \\\n",
       "0    -0.000732 -0.002646 -0.001011 -0.001619 -0.000548 -0.003270  0.003300   \n",
       "1    -0.000732 -0.002646 -0.001011 -0.001619 -0.000548 -0.003270  0.003300   \n",
       "2    -0.000732 -0.002646 -0.001011 -0.001619 -0.000548 -0.003270  0.003300   \n",
       "3    -0.000732 -0.002646 -0.001011 -0.001619 -0.000548 -0.003270  0.003300   \n",
       "4    -0.001372 -0.000927 -0.000884 -0.001822 -0.002552 -0.003918 -0.000138   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728  0.005464  0.003176  0.010693 -0.006413  0.006440  0.004761 -0.003553   \n",
       "3729  0.007128  0.001190  0.007030 -0.017283  0.012933  0.001416  0.002833   \n",
       "3730  0.023786  0.010913  0.020706 -0.025974  0.022801  0.001787  0.002249   \n",
       "3731  0.010651  0.005651  0.009712 -0.014924  0.016957 -0.003413  0.003462   \n",
       "3732  0.016123  0.013276  0.015529 -0.027641  0.019060 -0.011804  0.002870   \n",
       "\n",
       "          1242      1243      1244      1245      1246      1247      1248  \\\n",
       "0    -0.001119  0.002761 -0.003128 -0.001320 -0.001653  0.001773  0.000190   \n",
       "1    -0.001119  0.002761 -0.003128 -0.001320 -0.001653  0.001773  0.000190   \n",
       "2    -0.001119  0.002761 -0.003128 -0.001320 -0.001653  0.001773  0.000190   \n",
       "3    -0.001119  0.002761 -0.003128 -0.001320 -0.001653  0.001773  0.000190   \n",
       "4    -0.003113  0.010247 -0.004150  0.001844  0.001050  0.001722 -0.000648   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.003816 -0.005992 -0.011989  0.000153 -0.007802 -0.003251  0.000431   \n",
       "3729 -0.007273 -0.004733 -0.016409  0.000589 -0.013436 -0.003375 -0.001031   \n",
       "3730 -0.012384 -0.005151 -0.017593 -0.029052 -0.027120 -0.015469 -0.007616   \n",
       "3731 -0.003335 -0.000140 -0.014230 -0.009615 -0.018324 -0.003666 -0.004091   \n",
       "3732 -0.005589 -0.004730 -0.021442 -0.012115 -0.022686 -0.013018 -0.004547   \n",
       "\n",
       "          1249      1250      1251      1252      1253      1254      1255  \\\n",
       "0    -0.002786  0.000019 -0.000032 -0.000700  0.001483 -0.001075  0.000127   \n",
       "1    -0.002786  0.000019 -0.000032 -0.000700  0.001483 -0.001075  0.000127   \n",
       "2    -0.002786  0.000019 -0.000032 -0.000700  0.001483 -0.001075  0.000127   \n",
       "3    -0.002786  0.000019 -0.000032 -0.000700  0.001483 -0.001075  0.000127   \n",
       "4    -0.002731  0.002176  0.004739  0.000677 -0.000504  0.000284 -0.002619   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001739  0.002278 -0.006634 -0.003393  0.000610 -0.000999  0.002795   \n",
       "3729 -0.002515  0.000641 -0.006599 -0.003413  0.000296  0.005005  0.002982   \n",
       "3730  0.005637  0.002936  0.006068  0.009686 -0.003360 -0.004049  0.007157   \n",
       "3731  0.000284 -0.001322 -0.010377  0.007259 -0.004348 -0.000583 -0.001144   \n",
       "3732  0.006958  0.008048 -0.006868  0.010789 -0.007893 -0.001248  0.003799   \n",
       "\n",
       "          1256      1257      1258      1259      1260      1261      1262  \\\n",
       "0    -0.004206  0.002983  0.002385 -0.000605  0.002120 -0.001941 -0.000780   \n",
       "1    -0.004206  0.002983  0.002385 -0.000605  0.002120 -0.001941 -0.000780   \n",
       "2    -0.004206  0.002983  0.002385 -0.000605  0.002120 -0.001941 -0.000780   \n",
       "3    -0.004206  0.002983  0.002385 -0.000605  0.002120 -0.001941 -0.000780   \n",
       "4    -0.004979  0.000243  0.002140 -0.001091  0.001628 -0.001444 -0.000100   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.002429 -0.009753  0.000326  0.000340  0.012413 -0.003375  0.011150   \n",
       "3729 -0.002999 -0.009885  0.006631 -0.009635  0.009253 -0.002978  0.000200   \n",
       "3730 -0.006606 -0.009528  0.005363 -0.009573 -0.012623  0.015875 -0.008481   \n",
       "3731 -0.003976  0.002217  0.000805 -0.007403  0.000737  0.002015 -0.009409   \n",
       "3732 -0.002381 -0.006109  0.003281 -0.005142  0.000199 -0.000959 -0.021478   \n",
       "\n",
       "          1263      1264      1265      1266      1267      1268      1269  \\\n",
       "0    -0.000602 -0.002009  0.001643 -0.001074  0.004264 -0.000694  0.002568   \n",
       "1    -0.000602 -0.002009  0.001643 -0.001074  0.004264 -0.000694  0.002568   \n",
       "2    -0.000602 -0.002009  0.001643 -0.001074  0.004264 -0.000694  0.002568   \n",
       "3    -0.000602 -0.002009  0.001643 -0.001074  0.004264 -0.000694  0.002568   \n",
       "4     0.003363  0.002116 -0.000098 -0.004687 -0.001387 -0.001944  0.004386   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.004546  0.002729 -0.001479  0.007811  0.005798 -0.004262 -0.015676   \n",
       "3729 -0.008646  0.001253  0.003193  0.010034  0.006923 -0.007371 -0.008663   \n",
       "3730  0.002714  0.007982  0.015813  0.003552  0.024348  0.000703 -0.007246   \n",
       "3731 -0.002301  0.007608  0.011130  0.005080  0.003854 -0.003946 -0.004238   \n",
       "3732  0.004442  0.002498  0.018469 -0.004143  0.012593 -0.008374 -0.002815   \n",
       "\n",
       "          1270      1271      1272      1273      1274      1275      1276  \\\n",
       "0     0.003308 -0.002020  0.001025  0.004722 -0.002568  0.002179  0.005798   \n",
       "1     0.003308 -0.002020  0.001025  0.004722 -0.002568  0.002179  0.005798   \n",
       "2     0.003308 -0.002020  0.001025  0.004722 -0.002568  0.002179  0.005798   \n",
       "3     0.003308 -0.002020  0.001025  0.004722 -0.002568  0.002179  0.005798   \n",
       "4     0.004500 -0.003891  0.000193  0.006356 -0.002522  0.000102  0.003595   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "3728 -0.001840 -0.004580  0.003122 -0.008612 -0.006263 -0.000300 -0.000510   \n",
       "3729 -0.005403 -0.005219  0.003343  0.000165 -0.012555 -0.001912 -0.006776   \n",
       "3730  0.005146 -0.013379  0.015008  0.000395 -0.032967 -0.017383 -0.016805   \n",
       "3731  0.003537 -0.003510  0.002733  0.003851 -0.021861 -0.013896 -0.003653   \n",
       "3732  0.002150 -0.005808  0.013172  0.004673 -0.023360 -0.012518 -0.006254   \n",
       "\n",
       "          1277      1278      1279  pH2  len  \n",
       "0     0.000469 -0.003451 -0.001417  2.0  164  \n",
       "1     0.000469 -0.003451 -0.001417  4.2  164  \n",
       "2     0.000469 -0.003451 -0.001417  2.0  164  \n",
       "3     0.000469 -0.003451 -0.001417  6.5  164  \n",
       "4    -0.001726  0.001518 -0.000856  2.0  164  \n",
       "...        ...       ...       ...  ...  ...  \n",
       "3728  0.002007  0.003972 -0.000751  7.0   63  \n",
       "3729  0.009576 -0.001182 -0.004070  7.0   63  \n",
       "3730  0.029942 -0.025934 -0.007565  7.0   63  \n",
       "3731  0.011166 -0.012583 -0.003350  7.0   63  \n",
       "3732  0.014935 -0.020285 -0.000212  7.0   63  \n",
       "\n",
       "[3733 rows x 1282 columns]"
      ]
     },
     "execution_count": 144,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df.loc[:,features]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 51,
   "metadata": {},
   "outputs": [],
   "source": [
    "def run_kfold(Nfolds, seed):\n",
    "    \n",
    "    seed_everything(seed)\n",
    "    \n",
    "    test_preds = np.zeros((len(test_df), 1))\n",
    "    oofs = np.zeros((len(df), 1))\n",
    "    \n",
    "    for fold, (train_idx, valid_idx) in enumerate(GroupKFold(Nfolds).split(df, groups=df.group)):\n",
    "        train_df = df.iloc[train_idx]\n",
    "        valid_df = df.iloc[valid_idx]\n",
    "\n",
    "        train_ds = MyDataset(train_df,features,'y_normalize')\n",
    "        valid_ds = MyDataset(valid_df,features,'y_normalize')\n",
    "\n",
    "        train_dl = DataLoader(train_ds,bs=8,shuffle=True,num_workers=4,drop_last=True)\n",
    "        valid_dl = DataLoader(valid_ds,bs=8,shuffle=False,num_workers=4)\n",
    "\n",
    "        oof = np.zeros((len(df), 1))\n",
    "        best_loss = np.inf\n",
    "        \n",
    "        model = Model2(num_features,num_targets,hidden_size).cuda()\n",
    "        loss_fn = MSELossFlat()\n",
    "        optimizer = torch.optim.Adam(model.parameters(), lr=1e-3, weight_decay=1e-5)\n",
    "        scheduler = OneCycleLR(optimizer, max_lr=1e-2,steps_per_epoch=len(train_dl),div_factor=1e3, epochs=25,pct_start=0.1)\n",
    "\n",
    "        for epoch in range(10):\n",
    "            print(f\"Epoch {epoch+1}\\n-------------------------------\")\n",
    "            train_loss = train_fn(train_dl,model,loss_fn, optimizer,scheduler)\n",
    "            valid_loss,valid_preds = valid_fn(valid_dl,model,loss_fn)\n",
    "            spearman = stats.spearmanr(valid_preds, valid_ds.y)\n",
    "            print(f'In fold{fold} epoch{epoch}, train loss:{train_loss}, valid loss:{valid_loss},spearman:{spearman}')\n",
    "\n",
    "            if valid_loss < best_loss:\n",
    "                best_loss = valid_loss\n",
    "                oof[valid_idx] = valid_preds\n",
    "                torch.save(model.state_dict(),f'my_model/fold{fold}.pth')\n",
    "\n",
    "\n",
    "        test_ds = TestDataset(test_df,features)\n",
    "        test_dl = DataLoader(test_ds,bs=8,shuffle=False,num_workers=4)\n",
    "\n",
    "        model = Model2(num_features,num_targets,hidden_size)\n",
    "        model.load_state_dict(torch.load(f'my_model/fold{fold}.pth'))\n",
    "        model.to(device)\n",
    "\n",
    "        oofs+=oof/Nfolds\n",
    "\n",
    "        test_preds += test_fn(test_dl,model)/Nfolds\n",
    "        \n",
    "    \n",
    "\n",
    "    return test_preds, oofs\n",
    "    "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 52,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Epoch 1\n",
      "-------------------------------\n",
      "In fold0 epoch0, train loss:1.434931073321805, valid loss:14.619668229841269,spearman:SpearmanrResult(correlation=0.11455116312215358, pvalue=6.906415707203958e-07)\n",
      "Epoch 2\n",
      "-------------------------------\n",
      "In fold0 epoch1, train loss:1.024717537694223, valid loss:1.4275647434206982,spearman:SpearmanrResult(correlation=0.10978929843477474, pvalue=1.9713279845225363e-06)\n",
      "Epoch 3\n",
      "-------------------------------\n",
      "In fold0 epoch2, train loss:0.9458545974012097, valid loss:1.0320116445963454,spearman:SpearmanrResult(correlation=0.14043892547684603, pvalue=1.087603060461803e-09)\n",
      "Epoch 4\n",
      "-------------------------------\n",
      "In fold0 epoch3, train loss:0.8924413874041881, valid loss:1.0060919251722784,spearman:SpearmanrResult(correlation=0.14356329892362316, pvalue=4.5753399569586035e-10)\n",
      "Epoch 5\n",
      "-------------------------------\n",
      "In fold0 epoch4, train loss:0.8758156613282891, valid loss:1.208500983320877,spearman:SpearmanrResult(correlation=0.2277883425947571, pvalue=2.065351552735345e-23)\n",
      "Epoch 6\n",
      "-------------------------------\n",
      "In fold0 epoch5, train loss:0.8364020642612625, valid loss:1.283784544825729,spearman:SpearmanrResult(correlation=0.20617422389328904, pvalue=2.2196408830355106e-19)\n",
      "Epoch 7\n",
      "-------------------------------\n",
      "In fold0 epoch6, train loss:0.8306019992403718, valid loss:1.1686038523235829,spearman:SpearmanrResult(correlation=0.17531659168729566, pvalue=2.323053744183679e-14)\n",
      "Epoch 8\n",
      "-------------------------------\n",
      "In fold0 epoch7, train loss:0.8027439445513, valid loss:3.093781062401831,spearman:SpearmanrResult(correlation=0.13757450946818175, pvalue=2.366006471351305e-09)\n",
      "Epoch 9\n",
      "-------------------------------\n",
      "In fold0 epoch8, train loss:0.7722854137644491, valid loss:1.160296272394908,spearman:SpearmanrResult(correlation=0.19666508265158433, pvalue=9.641025299165696e-18)\n",
      "Epoch 10\n",
      "-------------------------------\n",
      "In fold0 epoch9, train loss:0.7732373721609811, valid loss:1.0085453133807223,spearman:SpearmanrResult(correlation=0.1459016032292248, pvalue=2.363734370577483e-10)\n",
      "Epoch 1\n",
      "-------------------------------\n",
      "In fold1 epoch0, train loss:1.5002957469915628, valid loss:1.2261442088354857,spearman:SpearmanrResult(correlation=0.15792052530044215, pvalue=6.963365625737139e-12)\n",
      "Epoch 2\n",
      "-------------------------------\n",
      "In fold1 epoch1, train loss:1.0266629880845803, valid loss:0.9570035153092482,spearman:SpearmanrResult(correlation=0.207493222407543, pvalue=1.3855476602792726e-19)\n",
      "Epoch 3\n",
      "-------------------------------\n",
      "In fold1 epoch2, train loss:0.9594057124315925, valid loss:0.9625505596781389,spearman:SpearmanrResult(correlation=0.17870147804826084, pvalue=7.555091720801456e-15)\n",
      "Epoch 4\n",
      "-------------------------------\n",
      "In fold1 epoch3, train loss:0.9579161875621444, valid loss:0.9533684748965197,spearman:SpearmanrResult(correlation=0.21261580533452393, pvalue=1.661427409490628e-20)\n",
      "Epoch 5\n",
      "-------------------------------\n",
      "In fold1 epoch4, train loss:0.9655491929709143, valid loss:1.0250660658965254,spearman:SpearmanrResult(correlation=0.1910300764235781, pvalue=8.724855269224104e-17)\n",
      "Epoch 6\n",
      "-------------------------------\n",
      "In fold1 epoch5, train loss:0.9303628940119252, valid loss:1.0575602886099846,spearman:SpearmanrResult(correlation=0.10448679342857745, pvalue=6.134907281867104e-06)\n",
      "Epoch 7\n",
      "-------------------------------\n",
      "In fold1 epoch6, train loss:0.9299525435326437, valid loss:1.0843889796867585,spearman:SpearmanrResult(correlation=0.22232685989478765, pvalue=2.558199049387294e-22)\n",
      "Epoch 8\n",
      "-------------------------------\n",
      "In fold1 epoch7, train loss:0.8967795166718602, valid loss:1.0266714831336567,spearman:SpearmanrResult(correlation=0.23710196822334967, pvalue=3.028836704317512e-25)\n",
      "Epoch 9\n",
      "-------------------------------\n",
      "In fold1 epoch8, train loss:0.8803433174099533, valid loss:1.008637259945146,spearman:SpearmanrResult(correlation=0.1646086663318524, pvalue=8.501959286873344e-13)\n",
      "Epoch 10\n",
      "-------------------------------\n",
      "In fold1 epoch9, train loss:0.833290560946444, valid loss:0.9677580603056102,spearman:SpearmanrResult(correlation=0.19405249601986935, pvalue=2.787112390425548e-17)\n"
     ]
    }
   ],
   "source": [
    "SEED = [0]\n",
    "\n",
    "oof = np.zeros((len(df), 1))\n",
    "test_preds = np.zeros((len(test_df), 1))\n",
    "\n",
    "for seed in SEED:\n",
    "    test_preds_, oof_ = run_kfold(2,seed)\n",
    "    test_preds+=test_preds_/len(SEED)\n",
    "    oof+=oof_/len(SEED)\n",
    "    \n",
    "df['oof'] = oof\n",
    "test_df['preds'] = test_preds"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
    "stats.spearmanr(valid_preds, valid_ds.y)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 53,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "df.plot.scatter(x='oof',y='y_normalize');"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 54,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "group\n",
       "0     0.073685\n",
       "1     0.271525\n",
       "2     0.162579\n",
       "3     0.310813\n",
       "4     0.207076\n",
       "5     0.178303\n",
       "6     0.139770\n",
       "7     0.224328\n",
       "8     0.009251\n",
       "9     0.251276\n",
       "10    0.062934\n",
       "11    0.315801\n",
       "12    0.431585\n",
       "13    0.388309\n",
       "14    0.299967\n",
       "15   -0.163214\n",
       "16   -0.012990\n",
       "17    0.170564\n",
       "18    0.324426\n",
       "19    0.571364\n",
       "20    0.076772\n",
       "21    0.313968\n",
       "22    0.497625\n",
       "23   -0.136987\n",
       "24    0.295745\n",
       "25    0.441062\n",
       "26    0.107100\n",
       "27    0.277696\n",
       "28    0.507661\n",
       "29    0.539755\n",
       "30    0.321945\n",
       "31   -0.148490\n",
       "32    0.191930\n",
       "34    0.177243\n",
       "35    0.463575\n",
       "36    0.007946\n",
       "38    0.452398\n",
       "39    0.173144\n",
       "40    0.039131\n",
       "41    0.273554\n",
       "dtype: float64"
      ]
     },
     "execution_count": 54,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df.groupby('group')[['oof','y_normalize']].apply(lambda x: x.corr('spearman').oof.y_normalize)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 77,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>oof</th>\n",
       "      <th>y_normalize</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>oof</th>\n",
       "      <td>1.000000</td>\n",
       "      <td>0.038054</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>y_normalize</th>\n",
       "      <td>0.038054</td>\n",
       "      <td>1.000000</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                  oof  y_normalize\n",
       "oof          1.000000     0.038054\n",
       "y_normalize  0.038054     1.000000"
      ]
     },
     "execution_count": 77,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df[['oof','y_normalize']].corr('spearman')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 162,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "array([[0.47156996],\n",
       "       [0.53584355],\n",
       "       [0.5202725 ],\n",
       "       ...,\n",
       "       [0.5280656 ],\n",
       "       [0.5192892 ],\n",
       "       [0.6572173 ]], dtype=float32)"
      ]
     },
     "execution_count": 162,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "test_preds"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 94,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "Sequential(\n",
       "  (0): Linear(in_features=1282, out_features=500, bias=True)\n",
       "  (1): BatchNorm1d(500, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (2): Linear(in_features=500, out_features=200, bias=True)\n",
       "  (3): BatchNorm1d(200, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n",
       "  (4): Linear(in_features=200, out_features=1, bias=True)\n",
       ")"
      ]
     },
     "execution_count": 94,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "model.cuda()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 95,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Epoch 1\n",
      "-------------------------------\n",
      "loss: 1.080293  [    0/ 3764]\n",
      "loss: 1.687482  [  800/ 3764]\n",
      "loss: 1.118925  [ 1600/ 3764]\n",
      "loss: 0.757889  [ 2400/ 3764]\n",
      "loss: 0.668643  [ 3200/ 3764]\n",
      "Test Error: Avg loss: 0.945010\n",
      "Epoch 2\n",
      "-------------------------------\n",
      "loss: 0.988457  [    0/ 3764]\n",
      "loss: 0.538472  [  800/ 3764]\n",
      "loss: 1.003537  [ 1600/ 3764]\n",
      "loss: 0.696454  [ 2400/ 3764]\n",
      "loss: 0.936770  [ 3200/ 3764]\n",
      "Test Error: Avg loss: 0.940664\n",
      "Epoch 3\n",
      "-------------------------------\n",
      "loss: 0.864447  [    0/ 3764]\n",
      "loss: 0.333849  [  800/ 3764]\n",
      "loss: 0.419051  [ 1600/ 3764]\n",
      "loss: 1.874793  [ 2400/ 3764]\n",
      "loss: 0.546775  [ 3200/ 3764]\n",
      "Test Error: Avg loss: 0.917771\n",
      "Epoch 4\n",
      "-------------------------------\n",
      "loss: 0.171663  [    0/ 3764]\n",
      "loss: 0.947445  [  800/ 3764]\n",
      "loss: 1.595440  [ 1600/ 3764]\n",
      "loss: 0.756516  [ 2400/ 3764]\n",
      "loss: 0.356026  [ 3200/ 3764]\n",
      "Test Error: Avg loss: 0.940091\n",
      "Epoch 5\n",
      "-------------------------------\n",
      "loss: 1.478294  [    0/ 3764]\n",
      "loss: 0.909177  [  800/ 3764]\n",
      "loss: 0.459987  [ 1600/ 3764]\n",
      "loss: 1.149477  [ 2400/ 3764]\n",
      "loss: 0.503476  [ 3200/ 3764]\n",
      "Test Error: Avg loss: 0.915178\n"
     ]
    }
   ],
   "source": [
    "for epoch in range(5):\n",
    "    print(f\"Epoch {epoch+1}\\n-------------------------------\")\n",
    "    train(dl)\n",
    "    test(dl)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 57,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine.to_csv('with_esm_feature.csv', index=False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 57,
   "metadata": {},
   "outputs": [],
   "source": [
    "gc.collect();torch.cuda.empty_cache()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Get WT feature"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 89,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_wt = pd.DataFrame(df2.wildtype.unique())"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 94,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_wt.rename(columns={0: 'protein_sequence'},inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 95,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "49ec8d1e790c4a93abd0c2240bddd63f",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "  0%|          | 0/78 [00:00<?, ?it/s]"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "wt_feature = get_feature_df(df_wt)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 99,
   "metadata": {},
   "outputs": [],
   "source": [
    "wt_combine = pd.concat([df_wt, wt_feature], axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 102,
   "metadata": {},
   "outputs": [],
   "source": [
    "wt_combine.to_csv('wildtype_feature.csv', index=False)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Get WT-mutant differences"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 112,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
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       "\n",
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       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>protein_sequence</th>\n",
       "      <th>0</th>\n",
       "      <th>1</th>\n",
       "      <th>2</th>\n",
       "      <th>3</th>\n",
       "      <th>4</th>\n",
       "      <th>5</th>\n",
       "      <th>6</th>\n",
       "      <th>7</th>\n",
       "      <th>8</th>\n",
       "      <th>...</th>\n",
       "      <th>1270</th>\n",
       "      <th>1271</th>\n",
       "      <th>1272</th>\n",
       "      <th>1273</th>\n",
       "      <th>1274</th>\n",
       "      <th>1275</th>\n",
       "      <th>1276</th>\n",
       "      <th>1277</th>\n",
       "      <th>1278</th>\n",
       "      <th>1279</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCND...</td>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDY...</td>\n",
       "      <td>-0.017728</td>\n",
       "      <td>0.002291</td>\n",
       "      <td>-0.005282</td>\n",
       "      <td>-0.005080</td>\n",
       "      <td>-0.027136</td>\n",
       "      <td>-0.036133</td>\n",
       "      <td>0.065131</td>\n",
       "      <td>0.004717</td>\n",
       "      <td>0.007467</td>\n",
       "      <td>...</td>\n",
       "      <td>0.056245</td>\n",
       "      <td>0.033457</td>\n",
       "      <td>-0.124666</td>\n",
       "      <td>-0.020386</td>\n",
       "      <td>0.027567</td>\n",
       "      <td>-0.074638</td>\n",
       "      <td>0.048811</td>\n",
       "      <td>-0.047698</td>\n",
       "      <td>0.007801</td>\n",
       "      <td>0.049899</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>MTDITANVVVSNPRPIFTESRSFKAVANGKIYIGQIDTDPVNPANQ...</td>\n",
       "      <td>0.016938</td>\n",
       "      <td>0.050288</td>\n",
       "      <td>0.001779</td>\n",
       "      <td>-0.010340</td>\n",
       "      <td>-0.100914</td>\n",
       "      <td>0.016280</td>\n",
       "      <td>0.007097</td>\n",
       "      <td>-0.068371</td>\n",
       "      <td>0.050936</td>\n",
       "      <td>...</td>\n",
       "      <td>0.037742</td>\n",
       "      <td>-0.022452</td>\n",
       "      <td>0.080056</td>\n",
       "      <td>0.028671</td>\n",
       "      <td>0.020483</td>\n",
       "      <td>0.058210</td>\n",
       "      <td>0.075229</td>\n",
       "      <td>-0.084503</td>\n",
       "      <td>0.046309</td>\n",
       "      <td>0.086032</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLK...</td>\n",
       "      <td>-0.011090</td>\n",
       "      <td>0.016666</td>\n",
       "      <td>-0.012930</td>\n",
       "      <td>0.030634</td>\n",
       "      <td>-0.012921</td>\n",
       "      <td>-0.012898</td>\n",
       "      <td>0.045492</td>\n",
       "      <td>-0.175886</td>\n",
       "      <td>0.034107</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.067271</td>\n",
       "      <td>-0.067047</td>\n",
       "      <td>-0.062890</td>\n",
       "      <td>-0.037578</td>\n",
       "      <td>-0.029985</td>\n",
       "      <td>0.007193</td>\n",
       "      <td>0.019816</td>\n",
       "      <td>-0.198807</td>\n",
       "      <td>-0.022456</td>\n",
       "      <td>0.110925</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>MRPSLPPLLTCLLAALPALLSAGCSPATPSAHAAEPASRNVPFPYA...</td>\n",
       "      <td>-0.005208</td>\n",
       "      <td>-0.068409</td>\n",
       "      <td>0.039885</td>\n",
       "      <td>-0.062333</td>\n",
       "      <td>0.012764</td>\n",
       "      <td>-0.049863</td>\n",
       "      <td>0.015773</td>\n",
       "      <td>-0.156441</td>\n",
       "      <td>-0.020250</td>\n",
       "      <td>...</td>\n",
       "      <td>-0.021826</td>\n",
       "      <td>-0.072720</td>\n",
       "      <td>-0.002612</td>\n",
       "      <td>-0.078776</td>\n",
       "      <td>-0.078234</td>\n",
       "      <td>0.016206</td>\n",
       "      <td>0.081448</td>\n",
       "      <td>-0.206387</td>\n",
       "      <td>0.055972</td>\n",
       "      <td>0.011760</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>5 rows × 1281 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "                                    protein_sequence         0         1  \\\n",
       "0  MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCND...  0.015805 -0.033919   \n",
       "1  MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDY... -0.017728  0.002291   \n",
       "2  MTDITANVVVSNPRPIFTESRSFKAVANGKIYIGQIDTDPVNPANQ...  0.016938  0.050288   \n",
       "3  MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLK... -0.011090  0.016666   \n",
       "4  MRPSLPPLLTCLLAALPALLSAGCSPATPSAHAAEPASRNVPFPYA... -0.005208 -0.068409   \n",
       "\n",
       "          2         3         4         5         6         7         8  ...  \\\n",
       "0  0.005356 -0.001142 -0.037829 -0.062076  0.034698  0.074689  0.025458  ...   \n",
       "1 -0.005282 -0.005080 -0.027136 -0.036133  0.065131  0.004717  0.007467  ...   \n",
       "2  0.001779 -0.010340 -0.100914  0.016280  0.007097 -0.068371  0.050936  ...   \n",
       "3 -0.012930  0.030634 -0.012921 -0.012898  0.045492 -0.175886  0.034107  ...   \n",
       "4  0.039885 -0.062333  0.012764 -0.049863  0.015773 -0.156441 -0.020250  ...   \n",
       "\n",
       "       1270      1271      1272      1273      1274      1275      1276  \\\n",
       "0  0.031189 -0.033546 -0.103467  0.056230 -0.052916 -0.003619 -0.020674   \n",
       "1  0.056245  0.033457 -0.124666 -0.020386  0.027567 -0.074638  0.048811   \n",
       "2  0.037742 -0.022452  0.080056  0.028671  0.020483  0.058210  0.075229   \n",
       "3 -0.067271 -0.067047 -0.062890 -0.037578 -0.029985  0.007193  0.019816   \n",
       "4 -0.021826 -0.072720 -0.002612 -0.078776 -0.078234  0.016206  0.081448   \n",
       "\n",
       "       1277      1278      1279  \n",
       "0 -0.058185  0.027794  0.081028  \n",
       "1 -0.047698  0.007801  0.049899  \n",
       "2 -0.084503  0.046309  0.086032  \n",
       "3 -0.198807 -0.022456  0.110925  \n",
       "4 -0.206387  0.055972  0.011760  \n",
       "\n",
       "[5 rows x 1281 columns]"
      ]
     },
     "execution_count": 112,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "wt_combine.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 113,
   "metadata": {},
   "outputs": [],
   "source": [
    "wt_combine.rename(columns={'protein_sequence': 'wildtype'},inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 117,
   "metadata": {},
   "outputs": [],
   "source": [
    "all_enzymes_wildtype_feature = df_combine[['wildtype']].merge(wt_combine)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 119,
   "metadata": {},
   "outputs": [],
   "source": [
    "all_enzymes_wildtype_feature.to_csv('all_enzymes_wildtype_feature.csv', index=False)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Get WT-mutant differences"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
    "# wt = pd.read_csv('all_enzymes_wildtype_feature.csv')\n",
    "# df_combine = pd.read_csv('all_enzymes_feature')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 124,
   "metadata": {},
   "outputs": [],
   "source": [
    "wt = all_enzymes_wildtype_feature.iloc[:,1:]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 133,
   "metadata": {},
   "outputs": [],
   "source": [
    "mutant = df_combine.iloc[:,-1280:]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 134,
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>0</th>\n",
       "      <th>1</th>\n",
       "      <th>2</th>\n",
       "      <th>3</th>\n",
       "      <th>4</th>\n",
       "      <th>5</th>\n",
       "      <th>6</th>\n",
       "      <th>7</th>\n",
       "      <th>8</th>\n",
       "      <th>9</th>\n",
       "      <th>...</th>\n",
       "      <th>1270</th>\n",
       "      <th>1271</th>\n",
       "      <th>1272</th>\n",
       "      <th>1273</th>\n",
       "      <th>1274</th>\n",
       "      <th>1275</th>\n",
       "      <th>1276</th>\n",
       "      <th>1277</th>\n",
       "      <th>1278</th>\n",
       "      <th>1279</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>0.099601</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>0.099601</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>0.099601</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>0.099601</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0.015805</td>\n",
       "      <td>-0.033919</td>\n",
       "      <td>0.005356</td>\n",
       "      <td>-0.001142</td>\n",
       "      <td>-0.037829</td>\n",
       "      <td>-0.062076</td>\n",
       "      <td>0.034698</td>\n",
       "      <td>0.074689</td>\n",
       "      <td>0.025458</td>\n",
       "      <td>0.099601</td>\n",
       "      <td>...</td>\n",
       "      <td>0.031189</td>\n",
       "      <td>-0.033546</td>\n",
       "      <td>-0.103467</td>\n",
       "      <td>0.056230</td>\n",
       "      <td>-0.052916</td>\n",
       "      <td>-0.003619</td>\n",
       "      <td>-0.020674</td>\n",
       "      <td>-0.058185</td>\n",
       "      <td>0.027794</td>\n",
       "      <td>0.081028</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6586</th>\n",
       "      <td>0.056222</td>\n",
       "      <td>-0.019059</td>\n",
       "      <td>0.034438</td>\n",
       "      <td>0.042787</td>\n",
       "      <td>-0.081775</td>\n",
       "      <td>0.047643</td>\n",
       "      <td>0.119286</td>\n",
       "      <td>-0.011242</td>\n",
       "      <td>-0.062220</td>\n",
       "      <td>-0.031445</td>\n",
       "      <td>...</td>\n",
       "      <td>0.063324</td>\n",
       "      <td>-0.103465</td>\n",
       "      <td>-0.039717</td>\n",
       "      <td>-0.029019</td>\n",
       "      <td>0.053409</td>\n",
       "      <td>-0.129892</td>\n",
       "      <td>0.118203</td>\n",
       "      <td>-0.196604</td>\n",
       "      <td>0.070822</td>\n",
       "      <td>0.114469</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6587</th>\n",
       "      <td>0.056222</td>\n",
       "      <td>-0.019059</td>\n",
       "      <td>0.034438</td>\n",
       "      <td>0.042787</td>\n",
       "      <td>-0.081775</td>\n",
       "      <td>0.047643</td>\n",
       "      <td>0.119286</td>\n",
       "      <td>-0.011242</td>\n",
       "      <td>-0.062220</td>\n",
       "      <td>-0.031445</td>\n",
       "      <td>...</td>\n",
       "      <td>0.063324</td>\n",
       "      <td>-0.103465</td>\n",
       "      <td>-0.039717</td>\n",
       "      <td>-0.029019</td>\n",
       "      <td>0.053409</td>\n",
       "      <td>-0.129892</td>\n",
       "      <td>0.118203</td>\n",
       "      <td>-0.196604</td>\n",
       "      <td>0.070822</td>\n",
       "      <td>0.114469</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6588</th>\n",
       "      <td>0.056222</td>\n",
       "      <td>-0.019059</td>\n",
       "      <td>0.034438</td>\n",
       "      <td>0.042787</td>\n",
       "      <td>-0.081775</td>\n",
       "      <td>0.047643</td>\n",
       "      <td>0.119286</td>\n",
       "      <td>-0.011242</td>\n",
       "      <td>-0.062220</td>\n",
       "      <td>-0.031445</td>\n",
       "      <td>...</td>\n",
       "      <td>0.063324</td>\n",
       "      <td>-0.103465</td>\n",
       "      <td>-0.039717</td>\n",
       "      <td>-0.029019</td>\n",
       "      <td>0.053409</td>\n",
       "      <td>-0.129892</td>\n",
       "      <td>0.118203</td>\n",
       "      <td>-0.196604</td>\n",
       "      <td>0.070822</td>\n",
       "      <td>0.114469</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6589</th>\n",
       "      <td>0.056222</td>\n",
       "      <td>-0.019059</td>\n",
       "      <td>0.034438</td>\n",
       "      <td>0.042787</td>\n",
       "      <td>-0.081775</td>\n",
       "      <td>0.047643</td>\n",
       "      <td>0.119286</td>\n",
       "      <td>-0.011242</td>\n",
       "      <td>-0.062220</td>\n",
       "      <td>-0.031445</td>\n",
       "      <td>...</td>\n",
       "      <td>0.063324</td>\n",
       "      <td>-0.103465</td>\n",
       "      <td>-0.039717</td>\n",
       "      <td>-0.029019</td>\n",
       "      <td>0.053409</td>\n",
       "      <td>-0.129892</td>\n",
       "      <td>0.118203</td>\n",
       "      <td>-0.196604</td>\n",
       "      <td>0.070822</td>\n",
       "      <td>0.114469</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6590</th>\n",
       "      <td>0.056222</td>\n",
       "      <td>-0.019059</td>\n",
       "      <td>0.034438</td>\n",
       "      <td>0.042787</td>\n",
       "      <td>-0.081775</td>\n",
       "      <td>0.047643</td>\n",
       "      <td>0.119286</td>\n",
       "      <td>-0.011242</td>\n",
       "      <td>-0.062220</td>\n",
       "      <td>-0.031445</td>\n",
       "      <td>...</td>\n",
       "      <td>0.063324</td>\n",
       "      <td>-0.103465</td>\n",
       "      <td>-0.039717</td>\n",
       "      <td>-0.029019</td>\n",
       "      <td>0.053409</td>\n",
       "      <td>-0.129892</td>\n",
       "      <td>0.118203</td>\n",
       "      <td>-0.196604</td>\n",
       "      <td>0.070822</td>\n",
       "      <td>0.114469</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>6591 rows × 1280 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "          0         1         2         3         4         5         6     \\\n",
       "0     0.015805 -0.033919  0.005356 -0.001142 -0.037829 -0.062076  0.034698   \n",
       "1     0.015805 -0.033919  0.005356 -0.001142 -0.037829 -0.062076  0.034698   \n",
       "2     0.015805 -0.033919  0.005356 -0.001142 -0.037829 -0.062076  0.034698   \n",
       "3     0.015805 -0.033919  0.005356 -0.001142 -0.037829 -0.062076  0.034698   \n",
       "4     0.015805 -0.033919  0.005356 -0.001142 -0.037829 -0.062076  0.034698   \n",
       "...        ...       ...       ...       ...       ...       ...       ...   \n",
       "6586  0.056222 -0.019059  0.034438  0.042787 -0.081775  0.047643  0.119286   \n",
       "6587  0.056222 -0.019059  0.034438  0.042787 -0.081775  0.047643  0.119286   \n",
       "6588  0.056222 -0.019059  0.034438  0.042787 -0.081775  0.047643  0.119286   \n",
       "6589  0.056222 -0.019059  0.034438  0.042787 -0.081775  0.047643  0.119286   \n",
       "6590  0.056222 -0.019059  0.034438  0.042787 -0.081775  0.047643  0.119286   \n",
       "\n",
       "          7         8         9     ...      1270      1271      1272  \\\n",
       "0     0.074689  0.025458  0.099601  ...  0.031189 -0.033546 -0.103467   \n",
       "1     0.074689  0.025458  0.099601  ...  0.031189 -0.033546 -0.103467   \n",
       "2     0.074689  0.025458  0.099601  ...  0.031189 -0.033546 -0.103467   \n",
       "3     0.074689  0.025458  0.099601  ...  0.031189 -0.033546 -0.103467   \n",
       "4     0.074689  0.025458  0.099601  ...  0.031189 -0.033546 -0.103467   \n",
       "...        ...       ...       ...  ...       ...       ...       ...   \n",
       "6586 -0.011242 -0.062220 -0.031445  ...  0.063324 -0.103465 -0.039717   \n",
       "6587 -0.011242 -0.062220 -0.031445  ...  0.063324 -0.103465 -0.039717   \n",
       "6588 -0.011242 -0.062220 -0.031445  ...  0.063324 -0.103465 -0.039717   \n",
       "6589 -0.011242 -0.062220 -0.031445  ...  0.063324 -0.103465 -0.039717   \n",
       "6590 -0.011242 -0.062220 -0.031445  ...  0.063324 -0.103465 -0.039717   \n",
       "\n",
       "          1273      1274      1275      1276      1277      1278      1279  \n",
       "0     0.056230 -0.052916 -0.003619 -0.020674 -0.058185  0.027794  0.081028  \n",
       "1     0.056230 -0.052916 -0.003619 -0.020674 -0.058185  0.027794  0.081028  \n",
       "2     0.056230 -0.052916 -0.003619 -0.020674 -0.058185  0.027794  0.081028  \n",
       "3     0.056230 -0.052916 -0.003619 -0.020674 -0.058185  0.027794  0.081028  \n",
       "4     0.056230 -0.052916 -0.003619 -0.020674 -0.058185  0.027794  0.081028  \n",
       "...        ...       ...       ...       ...       ...       ...       ...  \n",
       "6586 -0.029019  0.053409 -0.129892  0.118203 -0.196604  0.070822  0.114469  \n",
       "6587 -0.029019  0.053409 -0.129892  0.118203 -0.196604  0.070822  0.114469  \n",
       "6588 -0.029019  0.053409 -0.129892  0.118203 -0.196604  0.070822  0.114469  \n",
       "6589 -0.029019  0.053409 -0.129892  0.118203 -0.196604  0.070822  0.114469  \n",
       "6590 -0.029019  0.053409 -0.129892  0.118203 -0.196604  0.070822  0.114469  \n",
       "\n",
       "[6591 rows x 1280 columns]"
      ]
     },
     "execution_count": 134,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "wt"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 172,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "wt.iloc[1,:].sort_values().reset_index(drop=True).plot.line();"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 168,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "wt.iloc[1,:].sort_values().plot.line();"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 166,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<Figure size 432x288 with 1 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "mutant.iloc[1,:].plot.line();"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 143,
   "metadata": {},
   "outputs": [],
   "source": [
    "difference = (wt-mutant)*100"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 146,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "0       0.320376\n",
       "1       0.481710\n",
       "2       0.312745\n",
       "3      -0.172836\n",
       "4       0.414252\n",
       "          ...   \n",
       "6586    0.675470\n",
       "6587    1.490860\n",
       "6588   -4.357233\n",
       "6589   -2.425898\n",
       "6590   -2.844078\n",
       "Length: 6591, dtype: float32"
      ]
     },
     "execution_count": 146,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "difference.sum(axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 147,
   "metadata": {},
   "outputs": [],
   "source": [
    "df_combine['difference'] = difference.sum(axis=1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 152,
   "metadata": {},
   "outputs": [],
   "source": [
    "sub = df_combine.query('split == \"test\"')[['seq_id','difference']]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 154,
   "metadata": {},
   "outputs": [],
   "source": [
    "sub.reset_index(inplace=True,drop=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 158,
   "metadata": {},
   "outputs": [],
   "source": [
    "sub.rename(columns ={'difference':'tm'}, inplace=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 160,
   "metadata": {},
   "outputs": [],
   "source": [
    "sub.to_csv('submission.csv', index=False)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 161,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "2413"
      ]
     },
     "execution_count": 161,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "len(sub)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "Python 3 (ipykernel)",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.9.13"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 4
}