diff --git a/CVO/cvo.owl b/CVO/cvo.owl
index 59b2fe7..9f8a336 100644
--- a/CVO/cvo.owl
+++ b/CVO/cvo.owl
@@ -16,7 +16,7 @@
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#">
-
+
en
Chris mungall
Erica Marcos
@@ -62,7 +62,7 @@
OWL-DL
Vaccine Ontology Cancer Vaccine View
- 2024-07-13
+ 2024-08-11
@@ -677,6 +677,50 @@ WHERE {
+
+
+
+
+
+ is part of
+ my brain is part of my body (continuant parthood, two material entities)
+ my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
+ this day is part of this year (occurrent parthood)
+ a core relation that holds between a part and its whole
+ Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
+ Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
+ Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)
+
+A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
+ part_of
+
+ part of
+ http://www.obofoundry.org/ro/#OBO_REL:part_of
+
+
+
+
+
+
+
+
+ has part
+ my body has part my brain (continuant parthood, two material entities)
+ my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
+ this year has part this day (occurrent parthood)
+ a core relation that holds between a whole and its part
+ Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
+ Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
+ Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)
+
+A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
+ has_part
+
+ has part
+
+
+
+
@@ -717,14 +761,10 @@ WHERE {
-
-
-
-
-
+
+
has_specified_input
- has_specified_input
see is_input_of example_of_usage
The inverse property of is_specified_input_of
@@ -743,6 +783,7 @@ WHERE {
+
is_specified_input_of
some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
@@ -758,14 +799,10 @@ WHERE {
-
-
-
-
-
+
+
has_specified_output
- has_specified_output
The inverse property of is_specified_output_of
PERSON: Alan Ruttenberg
@@ -782,8 +819,8 @@ WHERE {
+
is_specified_output_of
- is_specified_output_of
A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
Alan Ruttenberg
@@ -797,6 +834,9 @@ WHERE {
+
+
+
achieves_planned_objective
A cell sorting process achieves the objective specification 'material separation objective'
@@ -810,6 +850,22 @@ WHERE {
+
+
+
+
+
+ objective_achieved_by
+
+ This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
+ OBI
+ OBI
+
+ objective_achieved_by
+
+
+
+
@@ -1224,6 +1280,12 @@ Ranges: organism and 'has role' some 'pathogen role'
+
+
+
+
+
+
continuant
Continuant
An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
@@ -1300,6 +1362,12 @@ Ranges: organism and 'has role' some 'pathogen role'
+
+
+
+
+
+
occurrent
Occurrent
An entity that has temporal parts and that happens, unfolds or develops through time.
@@ -1924,11 +1992,11 @@ Ranges: organism and 'has role' some 'pathogen role'
- An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract.
+ An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract.
disease_ontology
DOID:0050615
- respiratory system cancer
+ respiratory system cancer
@@ -1937,14 +2005,14 @@ Ranges: organism and 'has role' some 'pathogen role'
- A cancer that is classified based on the organ it starts in.
+ A cancer that is classified based on the organ it starts in.
snadendla
2011-06-13T03:28:33Z
MESH:D009371
disease_ontology
DOID:0050686
- organ system cancer
+ organ system cancer
@@ -1953,14 +2021,14 @@ Ranges: organism and 'has role' some 'pathogen role'
- A cancer that is classified by the type of cell from which it is derived.
+ A cancer that is classified by the type of cell from which it is derived.
snadendla
2011-06-13T03:28:50Z
disease_ontology
DOID:0050687
- cell type cancer
+ cell type cancer
@@ -1969,7 +2037,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles.
+ A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles.
lschriml
2012-09-18T02:00:45Z
@@ -1980,7 +2048,7 @@ Ranges: organism and 'has role' some 'pathogen role'DOID:0050746
- mantle cell lymphoma
+ mantle cell lymphoma
@@ -1990,7 +2058,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.
+ A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.
DOID:1033
DOID:353
@@ -2009,7 +2077,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- lymphoma
+ lymphoma
@@ -2018,13 +2086,13 @@ Ranges: organism and 'has role' some 'pathogen role'
- An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue.
+ An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue.
lschriml
2011-05-11T01:05:14Z
disease_ontology
DOID:0060073
- lymphatic system cancer
+ lymphatic system cancer
@@ -2034,7 +2102,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system.
+ An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system.
lschriml
2011-06-08T01:11:18Z
@@ -2042,7 +2110,7 @@ Ranges: organism and 'has role' some 'pathogen role'disease_ontology
DOID:0060083
- immune system cancer
+ immune system cancer
@@ -2052,7 +2120,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs.
+ An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs.
lschriml
2011-07-15T02:30:51Z
@@ -2060,7 +2128,7 @@ Ranges: organism and 'has role' some 'pathogen role'skeletal system cancer
disease_ontology
DOID:0060100
- musculoskeletal system cancer
+ musculoskeletal system cancer
@@ -2069,7 +2137,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A disease of anatomical entity that is located_in the thoracic cavity.
+ A disease of anatomical entity that is located_in the thoracic cavity.
lschriml
2011-07-25T02:23:47Z
@@ -2079,7 +2147,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- thoracic disease
+ thoracic disease
@@ -2088,7 +2156,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A gastrointestinal system cancer that is located_in the pharynx.
+ A gastrointestinal system cancer that is located_in the pharynx.
lschriml
2011-07-27T01:26:34Z
@@ -2103,7 +2171,7 @@ Ranges: organism and 'has role' some 'pathogen role'DOID:0060119
- pharynx cancer
+ pharynx cancer
@@ -2112,7 +2180,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A gastrointestinal system cancer that is located_in the hepatobiliary system.
+ A gastrointestinal system cancer that is located_in the hepatobiliary system.
disease_ontology
DOID:0080355
@@ -2125,7 +2193,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- An intestinal cancer that is located_in the small intestine.
+ An intestinal cancer that is located_in the small intestine.
GARD:9385
ICD10CM:C17
@@ -2137,7 +2205,7 @@ Ranges: organism and 'has role' some 'pathogen role'DOID:10154
- small intestine cancer
+ small intestine cancer
@@ -2147,7 +2215,7 @@ Ranges: organism and 'has role' some 'pathogen role'
- A gastrointestinal system cancer that is located_in the intestine.
+ A gastrointestinal system cancer that is located_in the intestine.
ICD10CM:C26.0
ICD9CM:159.0
@@ -2161,7 +2229,7 @@ Ranges: organism and 'has role' some 'pathogen role'DOID:10155
- intestinal cancer
+ intestinal cancer
@@ -2170,32 +2238,32 @@ Ranges: organism and 'has role' some 'pathogen role'
- A male reproductive organ cancer that is located_in the prostate.
+ A male reproductive organ cancer that is located_in the prostate.
DOID:514
ICD10CM:C61
ICD9CM:185
KEGG:05215
MESH:D011471
+ MIM:176807
+ MIM:300147
+ MIM:300704
+ MIM:601518
+ MIM:602759
+ MIM:608656
+ MIM:608658
+ MIM:609299
+ MIM:609558
+ MIM:610321
+ MIM:610997
+ MIM:611100
+ MIM:611868
+ MIM:611928
+ MIM:611955
+ MIM:611958
+ MIM:611959
NCI:C3343
NCI:C7378
- OMIM:176807
- OMIM:300147
- OMIM:300704
- OMIM:601518
- OMIM:602759
- OMIM:608656
- OMIM:608658
- OMIM:609299
- OMIM:609558
- OMIM:610321
- OMIM:610997
- OMIM:611100
- OMIM:611868
- OMIM:611928
- OMIM:611955
- OMIM:611958
- OMIM:611959
ORDO:1331
SNOMEDCT_US_2023_03_01:126906006
SNOMEDCT_US_2023_03_01:93974005
@@ -2217,9 +2285,9 @@ Ranges: organism and 'has role' some 'pathogen role'
- Xref MGI.
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- prostate cancer
+ prostate cancer
@@ -2228,7 +2296,7 @@ OMIM mapping confirmed by DO. [SN].
- A gastrointestinal system cancer that is located_in the stomach.
+ A gastrointestinal system cancer that is located_in the stomach.
DOID:10539
DOID:10542
@@ -2244,9 +2312,9 @@ OMIM mapping confirmed by DO. [SN].
ICD9CM:151.5
ICD9CM:151.6
MESH:D013274
+ MIM:613659
NCI:C3387
NCI:C9331
- OMIM:613659
SNOMEDCT_US_2023_03_01:126824007
SNOMEDCT_US_2023_03_01:269459004
SNOMEDCT_US_2023_03_01:269460009
@@ -2268,8 +2336,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- stomach cancer
+ OMIM mapping confirmed by DO. [SN].
+ stomach cancer
@@ -2279,7 +2347,7 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive system disease that is located_in the ovary.
+ A female reproductive system disease that is located_in the ovary.
MESH:D010049
NCI:C26841
@@ -2288,7 +2356,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:1100
- ovarian disease
+ ovarian disease
@@ -2297,7 +2365,7 @@ OMIM mapping confirmed by DO. [SN].
- An urinary system cancer that results_in malignant growth located_in the urinary bladder.
+ An urinary system cancer that results_in malignant growth located_in the urinary bladder.
DOID:5428
GARD:12210
@@ -2305,9 +2373,9 @@ OMIM mapping confirmed by DO. [SN].
ICD9CM:188
KEGG:05219
MESH:D001749
+ MIM:109800
NCI:C2901
NCI:C9334
- OMIM:109800
SNOMEDCT_US_2023_03_01:126885006
SNOMEDCT_US_2023_03_01:363455001
UMLS_CUI:C0005684
@@ -2322,8 +2390,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- urinary bladder cancer
+ OMIM mapping confirmed by DO. [SN].
+ urinary bladder cancer
@@ -2332,7 +2400,7 @@ OMIM mapping confirmed by DO. [SN].
- A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.
+ A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.
DOID:3936
ICD10CM:C49
@@ -2347,7 +2415,7 @@ OMIM mapping confirmed by DO. [SN].
- sarcoma
+ sarcoma
@@ -2356,7 +2424,7 @@ OMIM mapping confirmed by DO. [SN].
- A nervous system cancer that is located in the peripheral nervous system.
+ A nervous system cancer that is located in the peripheral nervous system.
DOID:3194
MESH:D010524
@@ -2374,7 +2442,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:1192
- peripheral nervous system neoplasm
+ peripheral nervous system neoplasm
@@ -2383,7 +2451,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx.
+ An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx.
GARD:12425
MESH:D006258
@@ -2402,7 +2470,7 @@ OMIM mapping confirmed by DO. [SN].
- head and neck cancer
+ head and neck cancer
@@ -2412,7 +2480,7 @@ OMIM mapping confirmed by DO. [SN].
- A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva.
+ A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva.
DOID:1244
DOID:1281
@@ -2433,7 +2501,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:120
- female reproductive organ cancer
+ female reproductive organ cancer
@@ -2442,7 +2510,7 @@ OMIM mapping confirmed by DO. [SN].
- A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
+ A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.
DOID:9145
ICD10CM:C95.90
@@ -2457,7 +2525,7 @@ OMIM mapping confirmed by DO. [SN].
- leukemia
+ leukemia
@@ -2466,7 +2534,7 @@ OMIM mapping confirmed by DO. [SN].
- A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.
+ A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.
DOID:2125
DOID:2126
@@ -2514,7 +2582,7 @@ OMIM mapping confirmed by DO. [SN].
- brain cancer
+ brain cancer
@@ -2523,7 +2591,7 @@ OMIM mapping confirmed by DO. [SN].
- A respiratory system cancer that is located_in the lung.
+ A respiratory system cancer that is located_in the lung.
DOID:13075
DOID:1322
@@ -2535,11 +2603,11 @@ OMIM mapping confirmed by DO. [SN].
ICD9CM:162.4
ICD9CM:162.5
ICD9CM:162.8
- OMIM:211980
- OMIM:608935
- OMIM:612571
- OMIM:612593
- OMIM:614210
+ MIM:211980
+ MIM:608935
+ MIM:612571
+ MIM:612593
+ MIM:614210
SNOMEDCT_US_2023_03_01:187860004
SNOMEDCT_US_2023_03_01:187864008
SNOMEDCT_US_2023_03_01:187868006
@@ -2554,7 +2622,7 @@ OMIM mapping confirmed by DO. [SN].
- lung cancer
+ lung cancer
@@ -2563,7 +2631,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease that is characterized by abnormally rapid cell division.
+ A disease that is characterized by abnormally rapid cell division.
neoplasm
DOID:0000818
@@ -2573,7 +2641,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:14566
- disease of cellular proliferation
+ disease of cellular proliferation
@@ -2582,7 +2650,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in reproductive system organs.
+ A disease of anatomical entity that is located_in reproductive system organs.
DOID:6309
NCI:C27613
@@ -2595,7 +2663,7 @@ OMIM mapping confirmed by DO. [SN].
- reproductive system disease
+ reproductive system disease
@@ -2605,7 +2673,7 @@ OMIM mapping confirmed by DO. [SN].
- A head and neck cancer that has_material_basis_in epithelial cells and is located in the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx.
+ A head and neck cancer that has_material_basis_in epithelial cells and is located in the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx.
NCI:C6077
UMLS_CUI:C1334927
@@ -2615,7 +2683,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:1542
- head and neck carcinoma
+ head and neck carcinoma
@@ -2624,7 +2692,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm.
+ A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm.
DOID:3226
ICD10CM:J98
@@ -2638,7 +2706,7 @@ OMIM mapping confirmed by DO. [SN].
- respiratory system disease
+ respiratory system disease
@@ -2647,14 +2715,14 @@ OMIM mapping confirmed by DO. [SN].
- A thoracic cancer that originates in the mammary gland.
+ A thoracic cancer that originates in the mammary gland.
DOID:1648
DOID:4241
ICD10CM:C50
MESH:D001943
+ MIM:114480
NCI:C9335
- OMIM:114480
SNOMEDCT_US_2023_03_01:254837009
UMLS_CUI:C0006142
breast tumor
@@ -2671,9 +2739,9 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- breast cancer
+ breast cancer
@@ -2682,7 +2750,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
+ A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
ICD10CM:C80.1
ICD9CM:199
@@ -2703,8 +2771,8 @@ OMIM mapping confirmed by DO. [SN].
- Updating out dated UMLS CUI.
- cancer
+ Updating out dated UMLS CUI.
+ cancer
@@ -2713,7 +2781,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that occurs in the muscular and/or skeletal system.
+ A disease of anatomical entity that occurs in the muscular and/or skeletal system.
MESH:D009140
NCI:C107377
@@ -2726,7 +2794,7 @@ OMIM mapping confirmed by DO. [SN].
- musculoskeletal system disease
+ musculoskeletal system disease
@@ -2735,7 +2803,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system.
+ An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system.
DOID:10009
ICD10CM:C75.9
@@ -2758,7 +2826,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:170
- endocrine gland cancer
+ endocrine gland cancer
@@ -2768,7 +2836,7 @@ OMIM mapping confirmed by DO. [SN].
- An endocrine gland cancer located_in the pancreas.
+ An endocrine gland cancer located_in the pancreas.
DOID:14356
DOID:1797
@@ -2813,8 +2881,8 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
- pancreatic cancer
+ Xref MGI.
+ pancreatic cancer
@@ -2823,7 +2891,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.
+ A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.
DOID:579
NCI:C27599
@@ -2837,7 +2905,7 @@ OMIM mapping confirmed by DO. [SN].
- urinary system disease
+ urinary system disease
@@ -2846,7 +2914,7 @@ OMIM mapping confirmed by DO. [SN].
- A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue.
+ A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue.
DOID:3348
MESH:D001859
@@ -2866,7 +2934,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:184
- bone cancer
+ bone cancer
@@ -2875,7 +2943,7 @@ OMIM mapping confirmed by DO. [SN].
- A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.
+ A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.
EFO:0000756
ICDO:8720/3
@@ -2892,7 +2960,7 @@ OMIM mapping confirmed by DO. [SN].
- melanoma
+ melanoma
MESH:D008545
@@ -2903,7 +2971,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer that is manifested in the reproductive organs.
+ An organ system cancer that is manifested in the reproductive organs.
DOID:1900
NCI:C3674
@@ -2914,7 +2982,7 @@ OMIM mapping confirmed by DO. [SN].
cancer of reproductive system
DOID:193
- reproductive organ cancer
+ reproductive organ cancer
@@ -2923,7 +2991,7 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive organ cancer that is located_in fallopian tube.
+ A female reproductive organ cancer that is located_in fallopian tube.
DOID:1961
GARD:9162
@@ -2948,7 +3016,7 @@ OMIM mapping confirmed by DO. [SN].
- fallopian tube cancer
+ fallopian tube cancer
@@ -2957,7 +3025,7 @@ OMIM mapping confirmed by DO. [SN].
- A colorectal cancer that is located_in the rectum.
+ A colorectal cancer that is located_in the rectum.
DOID:1989
ICD10CM:C20
@@ -2982,7 +3050,7 @@ OMIM mapping confirmed by DO. [SN].
- rectum cancer
+ rectum cancer
@@ -2992,19 +3060,19 @@ OMIM mapping confirmed by DO. [SN].
- A musculoskeletal system cancer that is located_in connective tissue.
+ A musculoskeletal system cancer that is located_in connective tissue.
MESH:D009372
SNOMEDCT_US_2023_03_01:126598008
UMLS_CUI:C0027656
Tumour of connective tissue
connective tissue neoplasm
- mesenchymal tissue malignant neoplasm
+ mesenchymal tissue malignant neoplasm
neoplasm of connective tissues
disease_ontology
DOID:201
- connective tissue cancer
+ connective tissue cancer
@@ -3013,7 +3081,7 @@ OMIM mapping confirmed by DO. [SN].
- A colorectal cancer that is located_in the colon.
+ A colorectal cancer that is located_in the colon.
ICD10CM:C18
ICD9CM:153
@@ -3026,7 +3094,7 @@ OMIM mapping confirmed by DO. [SN].
- colon cancer
+ colon cancer
@@ -3035,7 +3103,7 @@ OMIM mapping confirmed by DO. [SN].
- A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes.
+ A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes.
ICD9CM:629.9
MESH:D005831
@@ -3043,7 +3111,7 @@ OMIM mapping confirmed by DO. [SN].
UMLS_CUI:C0017411
disease_ontology
DOID:229
- female reproductive system disease
+ female reproductive system disease
@@ -3053,7 +3121,7 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive organ cancer that is located_in the ovary.
+ A female reproductive organ cancer that is located_in the ovary.
DOID:0060070
DOID:2144
@@ -3062,10 +3130,10 @@ OMIM mapping confirmed by DO. [SN].
ICD10CM:C56
ICD9CM:183.0
MESH:D010051
+ MIM:167000
+ MIM:607893
NCI:C4984
NCI:C7431
- OMIM:167000
- OMIM:607893
ORDO:213500
ORDO:213517
SNOMEDCT_US_2023_03_01:123843001
@@ -3089,9 +3157,9 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- ovarian cancer
+ ovarian cancer
@@ -3101,7 +3169,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.
+ An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.
DOID:1034
DOID:2532
@@ -3126,7 +3194,7 @@ OMIM mapping confirmed by DO. [SN].
- hematologic cancer
+ hematologic cancer
@@ -3135,7 +3203,7 @@ OMIM mapping confirmed by DO. [SN].
- A urinary system cancer that is located_in the kidney.
+ A urinary system cancer that is located_in the kidney.
DOID:11834
DOID:3676
@@ -3159,7 +3227,7 @@ OMIM mapping confirmed by DO. [SN].
- kidney cancer
+ kidney cancer
@@ -3168,7 +3236,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body.
+ A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body.
ICD10CM:E34.9
ICD9CM:259.9
@@ -3184,7 +3252,7 @@ OMIM mapping confirmed by DO. [SN].
- endocrine system disease
+ endocrine system disease
@@ -3193,7 +3261,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in the immune system.
+ A disease of anatomical entity that is located_in the immune system.
EFO:0000540
ICD10CM:D89.9
@@ -3207,7 +3275,7 @@ OMIM mapping confirmed by DO. [SN].
- immune system disease
+ immune system disease
@@ -3216,7 +3284,7 @@ OMIM mapping confirmed by DO. [SN].
- A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.
+ A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.
ICDO:8140/3
MESH:D000230
@@ -3226,7 +3294,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:299
- adenocarcinoma
+ adenocarcinoma
MESH:D000230
@@ -3236,7 +3304,7 @@ OMIM mapping confirmed by DO. [SN].
- A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
+ A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
DOID:2428
DOID:6570
@@ -3259,7 +3327,7 @@ OMIM mapping confirmed by DO. [SN].
- carcinoma
+ carcinoma
@@ -3268,7 +3336,7 @@ OMIM mapping confirmed by DO. [SN].
- A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
+ A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
DOID:3075
DOID:3080
@@ -3284,7 +3352,7 @@ OMIM mapping confirmed by DO. [SN].
UMLS_CUI:C1514422
GBM
adult glioblastoma multiforme
- glioblastoma multiforme
+ glioblastoma multiforme
grade IV adult Astrocytic tumor
primary glioblastoma multiforme
spongioblastoma multiforme
@@ -3293,7 +3361,7 @@ OMIM mapping confirmed by DO. [SN].
- glioblastoma
+ glioblastoma
@@ -3303,7 +3371,7 @@ OMIM mapping confirmed by DO. [SN].
- A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.
+ A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.
DOID:4861
ICDO:9400/3
@@ -3323,7 +3391,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:3069
- malignant astrocytoma
+ malignant astrocytoma
MESH:D001254
@@ -3334,7 +3402,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer located_in the nervous system that affects the central or peripheral nervous system.
+ An organ system cancer located_in the nervous system that affects the central or peripheral nervous system.
DOID:1193
DOID:3195
@@ -3355,7 +3423,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:3093
- nervous system cancer
+ nervous system cancer
@@ -3364,7 +3432,7 @@ OMIM mapping confirmed by DO. [SN].
- A gastrointestinal system disease that is located_in the liver and/or biliary tract.
+ A gastrointestinal system disease that is located_in the liver and/or biliary tract.
MESH:D004066
NCI:C3959
@@ -3373,7 +3441,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:3118
- hepatobiliary disease
+ hepatobiliary disease
@@ -3383,7 +3451,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system.
+ An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system.
DOID:4945
DOID:8377
@@ -3408,7 +3476,7 @@ OMIM mapping confirmed by DO. [SN].
- gastrointestinal system cancer
+ gastrointestinal system cancer
@@ -3417,15 +3485,15 @@ OMIM mapping confirmed by DO. [SN].
- A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin.
+ A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).
DOID:183
GARD:7284
ICDO:9180/3
MESH:D012516
MESH:D018213
+ MIM:259500
NCI:C9145
- OMIM:259500
ORDO:668
SNOMEDCT_US_2023_03_01:189878003
UMLS_CUI:C0029463
@@ -3439,8 +3507,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- osteosarcoma
+ OMIM mapping confirmed by DO. [SN].
+ osteosarcoma
@@ -3449,7 +3517,7 @@ OMIM mapping confirmed by DO. [SN].
- A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm.
+ A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm.
DOID:0050607
DOID:4158
@@ -3462,13 +3530,13 @@ OMIM mapping confirmed by DO. [SN].
MESH:C563168
MESH:D012512
MESH:D018241
+ MIM:612219
NCI:C27901
NCI:C27903
NCI:C4817
NCI:C7542
NCI:C7806
NCI:C9341
- OMIM:612219
SNOMEDCT_US_2023_03_01:134210007
SNOMEDCT_US_2023_03_01:73676002
SNOMEDCT_US_2023_03_01:76909002
@@ -3495,8 +3563,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- Ewing sarcoma
+ OMIM mapping confirmed by DO. [SN].
+ Ewing sarcoma
@@ -3505,7 +3573,7 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive system disease that is located_in the uterus.
+ A female reproductive system disease that is located_in the uterus.
ICD10CM:N85.9
ICD9CM:621.9
@@ -3516,7 +3584,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:345
- uterine disease
+ uterine disease
@@ -3527,7 +3595,7 @@ OMIM mapping confirmed by DO. [SN].
- A hepatobiliary system cancer that is located_in the liver.
+ A hepatobiliary system cancer that is located_in the liver.
DOID:12300
DOID:269
@@ -3569,7 +3637,7 @@ OMIM mapping confirmed by DO. [SN].
- liver cancer
+ liver cancer
@@ -3578,7 +3646,7 @@ OMIM mapping confirmed by DO. [SN].
- A nervous system cancer that is located_in the central nervous system.
+ A nervous system cancer that is located_in the central nervous system.
DOID:0060093
DOID:1318
@@ -3600,7 +3668,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:3620
- central nervous system cancer
+ central nervous system cancer
@@ -3610,7 +3678,7 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive organ cancer that is located_in the uterus.
+ A female reproductive organ cancer that is located_in the uterus.
DOID:4363
ICD10CM:C55
@@ -3635,7 +3703,7 @@ OMIM mapping confirmed by DO. [SN].
- uterine cancer
+ uterine cancer
@@ -3645,7 +3713,7 @@ OMIM mapping confirmed by DO. [SN].
- A stomach carcinoma that derives_from epithelial cells of glandular origin.
+ A stomach carcinoma that derives_from epithelial cells of glandular origin.
NCI:C4004
SNOMEDCT_US_2023_03_01:408647009
@@ -3656,7 +3724,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:3717
- gastric adenocarcinoma
+ gastric adenocarcinoma
@@ -3665,7 +3733,7 @@ OMIM mapping confirmed by DO. [SN].
- A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum.
+ A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum.
DOID:10284
ICD10CM:C63.9
@@ -3690,7 +3758,7 @@ OMIM mapping confirmed by DO. [SN].
male genital neoplasm
DOID:3856
- male reproductive organ cancer
+ male reproductive organ cancer
@@ -3700,7 +3768,7 @@ OMIM mapping confirmed by DO. [SN].
- A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.
+ A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.
EFO:0001071
NCI:C4878
@@ -3712,8 +3780,8 @@ OMIM mapping confirmed by DO. [SN].
DOID:3905
- OMIM mapping confirmed by DO. [SN].
- lung carcinoma
+ OMIM mapping confirmed by DO. [SN].
+ lung carcinoma
@@ -3722,7 +3790,7 @@ OMIM mapping confirmed by DO. [SN].
- A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
+ A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
EFO:0003060
KEGG:05223
@@ -3737,7 +3805,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:3908
- lung non-small cell carcinoma
+ lung non-small cell carcinoma
@@ -3747,7 +3815,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra.
+ An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra.
ICD10CM:C68.9
ICD9CM:189.9
@@ -3755,7 +3823,7 @@ OMIM mapping confirmed by DO. [SN].
UMLS_CUI:C0348371
disease_ontology
DOID:3996
- urinary system cancer
+ urinary system cancer
@@ -3764,7 +3832,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
+ A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
MESH:D004194
NCI:C2991
@@ -3774,7 +3842,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:4
- disease
+ disease
@@ -3783,15 +3851,15 @@ OMIM mapping confirmed by DO. [SN].
- A female reproductive organ cancer that is located_in the cervix.
+ A female reproductive organ cancer that is located_in the cervix.
DOID:4361
ICD10CM:C53
ICD9CM:180
MESH:D002583
+ MIM:603956
NCI:C2940
NCI:C9311
- OMIM:603956
SNOMEDCT_US_2023_03_01:123841004
SNOMEDCT_US_2023_03_01:254885005
UMLS_CUI:C0007847
@@ -3808,7 +3876,7 @@ OMIM mapping confirmed by DO. [SN].
- cervical cancer
+ cervical cancer
@@ -3818,7 +3886,7 @@ OMIM mapping confirmed by DO. [SN].
- A biliary tract cancer that is located_in the bile duct.
+ A biliary tract cancer that is located_in the bile duct.
DOID:10019
ICD10CM:C24.0
@@ -3836,7 +3904,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:4606
- bile duct cancer
+ bile duct cancer
@@ -3846,7 +3914,7 @@ OMIM mapping confirmed by DO. [SN].
- A bile duct carcinoma that derives_from epithelial cells of glandular origin.
+ A bile duct carcinoma that derives_from epithelial cells of glandular origin.
NCI:C27813
SNOMEDCT_US_2023_03_01:70179006
@@ -3855,7 +3923,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:4896
- bile duct adenocarcinoma
+ bile duct adenocarcinoma
@@ -3865,7 +3933,7 @@ OMIM mapping confirmed by DO. [SN].
- A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
+ A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
MESH:D001650
NCI:C27814
@@ -3874,7 +3942,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:4897
- bile duct carcinoma
+ bile duct carcinoma
@@ -3883,7 +3951,7 @@ OMIM mapping confirmed by DO. [SN].
- A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.
+ A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.
DOID:5249
ICD10CM:C22.1
@@ -3901,7 +3969,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:4947
- cholangiocarcinoma
+ cholangiocarcinoma
@@ -3910,7 +3978,7 @@ OMIM mapping confirmed by DO. [SN].
- A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow.
+ A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow.
DOID:2356
DOID:2761
@@ -3926,7 +3994,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:4960
- bone marrow cancer
+ bone marrow cancer
@@ -3935,7 +4003,7 @@ OMIM mapping confirmed by DO. [SN].
- A gastrointestinal system cancer that is located_in the esophagus.
+ A gastrointestinal system cancer that is located_in the esophagus.
DOID:10291
DOID:10292
@@ -3952,12 +4020,12 @@ OMIM mapping confirmed by DO. [SN].
ICD9CM:150.5
ICD9CM:150.8
MESH:D004938
+ MIM:133239
NCI:C3028
NCI:C3533
NCI:C3534
NCI:C3535
NCI:C4764
- OMIM:133239
SNOMEDCT_US_2023_03_01:126817006
SNOMEDCT_US_2023_03_01:187729008
SNOMEDCT_US_2023_03_01:93656003
@@ -3990,7 +4058,7 @@ OMIM mapping confirmed by DO. [SN].
- esophageal cancer
+ esophageal cancer
@@ -4000,7 +4068,7 @@ OMIM mapping confirmed by DO. [SN].
- An organ system cancer located_in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall.
+ An organ system cancer located_in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall.
DOID:3937
ICD10CM:C76.1
@@ -4019,7 +4087,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:5093
- thoracic cancer
+ thoracic cancer
@@ -4028,7 +4096,7 @@ OMIM mapping confirmed by DO. [SN].
- A gastrointestinal system disease that is located_in the intestine.
+ A gastrointestinal system disease that is located_in the intestine.
DOID:10759
DOID:11222
@@ -4045,7 +4113,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:5295
- intestinal disease
+ intestinal disease
@@ -4054,21 +4122,21 @@ OMIM mapping confirmed by DO. [SN].
- A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.
+ A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.
DOID:0050875
KEGG:05222
MESH:D055752
+ MIM:182280
NCI:C4917
- OMIM:182280
SNOMEDCT_US_2023_03_01:254632001
UMLS_CUI:C0149925
disease_ontology
DOID:5409
- OMIM mapping confirmed by DO. [SN].
- lung small cell carcinoma
+ OMIM mapping confirmed by DO. [SN].
+ lung small cell carcinoma
@@ -4078,7 +4146,7 @@ OMIM mapping confirmed by DO. [SN].
- A stomach cancer that is located_in the stomach.
+ A stomach cancer that is located_in the stomach.
EFO:0000178
NCI:C4911
@@ -4091,7 +4159,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:5517
- stomach carcinoma
+ stomach carcinoma
@@ -4100,12 +4168,12 @@ OMIM mapping confirmed by DO. [SN].
- A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.
+ A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.
GARD:8503
MESH:D000077195
+ MIM:275355
NCI:C34447
- OMIM:275355
SNOMEDCT_US_2023_03_01:716659002
UMLS_CUI:C1168401
carcinoma of the head and neck
@@ -4116,8 +4184,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- head and neck squamous cell carcinoma
+ OMIM mapping confirmed by DO. [SN].
+ head and neck squamous cell carcinoma
@@ -4126,7 +4194,7 @@ OMIM mapping confirmed by DO. [SN].
- A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.
+ A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.
MESH:D003240
NCI:C26729
@@ -4137,7 +4205,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:65
- connective tissue disease
+ connective tissue disease
@@ -4146,7 +4214,7 @@ OMIM mapping confirmed by DO. [SN].
- A mature B-cell neoplasm that is composed of plasma cells.
+ A mature B-cell neoplasm that is composed of plasma cells.
EFO:0000200
MESH:D010265
@@ -4157,7 +4225,7 @@ OMIM mapping confirmed by DO. [SN].
Plasmacytic tumor
disease_ontology
DOID:6536
- plasma cell neoplasm
+ plasma cell neoplasm
@@ -4166,15 +4234,15 @@ OMIM mapping confirmed by DO. [SN].
- A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.
+ A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.
DOID:5005
EFO:0000182
ICD10CM:C22.0
ICDO:8170/3
MESH:D006528
+ MIM:114550
NCI:C3099
- OMIM:114550
ORDO:88673
SNOMEDCT_US_2023_03_01:154469006
UMLS_CUI:C2239176
@@ -4184,8 +4252,8 @@ OMIM mapping confirmed by DO. [SN].
- OMIM mapping confirmed by DO. [SN].
- hepatocellular carcinoma
+ OMIM mapping confirmed by DO. [SN].
+ hepatocellular carcinoma
@@ -4195,7 +4263,7 @@ OMIM mapping confirmed by DO. [SN].
- A liver cancer that has_material_basis_in epithelial cells.
+ A liver cancer that has_material_basis_in epithelial cells.
NCI:C7927
UMLS_CUI:C0279000
@@ -4203,7 +4271,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:686
- liver carcinoma
+ liver carcinoma
@@ -4212,7 +4280,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease that manifests in a defined anatomical structure.
+ A disease that manifests in a defined anatomical structure.
DOID:1
DOID:2
@@ -4223,7 +4291,7 @@ OMIM mapping confirmed by DO. [SN].
disease_ontology
DOID:7
- disease of anatomical entity
+ disease of anatomical entity
@@ -4232,7 +4300,7 @@ OMIM mapping confirmed by DO. [SN].
- A non-Hodgkin lymphoma that has_material_basis_in B cells.
+ A non-Hodgkin lymphoma that has_material_basis_in B cells.
GARD:5877
MESH:D016393
@@ -4245,7 +4313,7 @@ OMIM mapping confirmed by DO. [SN].
- B-cell lymphoma
+ B-cell lymphoma
@@ -4254,7 +4322,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that has_material_basis_in hematopoietic cells.
+ A disease of anatomical entity that has_material_basis_in hematopoietic cells.
ICD10CM:D75.9
ICD9CM:289.9
@@ -4277,7 +4345,7 @@ OMIM mapping confirmed by DO. [SN].
- hematopoietic system disease
+ hematopoietic system disease
@@ -4286,7 +4354,7 @@ OMIM mapping confirmed by DO. [SN].
- An autonomic nervous system neoplasm that derives_from immature nerve cells.
+ An autonomic nervous system neoplasm that derives_from immature nerve cells.
EFO:0000621
GARD:7185
@@ -4301,9 +4369,9 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- neuroblastoma
+ neuroblastoma
@@ -4312,7 +4380,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in the gastrointestinal tract.
+ A disease of anatomical entity that is located_in the gastrointestinal tract.
DOID:27
DOID:944
@@ -4333,7 +4401,7 @@ OMIM mapping confirmed by DO. [SN].
- gastrointestinal system disease
+ gastrointestinal system disease
@@ -4342,7 +4410,7 @@ OMIM mapping confirmed by DO. [SN].
- A pharynx cancer that is located_in the oropharynx.
+ A pharynx cancer that is located_in the oropharynx.
DOID:8684
DOID:8851
@@ -4373,7 +4441,7 @@ OMIM mapping confirmed by DO. [SN].
DOID:8557
- oropharynx cancer
+ oropharynx cancer
@@ -4382,7 +4450,7 @@ OMIM mapping confirmed by DO. [SN].
- A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.
+ A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.
ICD10CM:G98
ICD9CM:349.9
@@ -4396,7 +4464,7 @@ OMIM mapping confirmed by DO. [SN].
- nervous system disease
+ nervous system disease
@@ -4405,14 +4473,14 @@ OMIM mapping confirmed by DO. [SN].
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
+ A large intestine cancer that is located_in the colon and/or located_in the rectum.
ICD10CM:C18.9
KEGG:05210
MESH:D015179
+ MIM:114500
NCI:C2956
NCI:C4978
- OMIM:114500
SNOMEDCT_US_2023_03_01:126837005
SNOMEDCT_US_2023_03_01:93854002
UMLS_CUI:C0009404
@@ -4423,9 +4491,10 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
+
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- colorectal cancer
+ colorectal cancer
@@ -4436,7 +4505,7 @@ OMIM mapping confirmed by DO. [SN].
- A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.
+ A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.
DOID:8813
DOID:8814
@@ -4456,9 +4525,9 @@ OMIM mapping confirmed by DO. [SN].
ICD9CM:147.2
ICD9CM:147.3
MESH:D009303
+ MIM:161550
+ MIM:607107
NCI:C9321
- OMIM:161550
- OMIM:607107
ORDO:150
SNOMEDCT_US_2023_03_01:187692001
SNOMEDCT_US_2023_03_01:187693006
@@ -4482,9 +4551,9 @@ OMIM mapping confirmed by DO. [SN].
- Xref MGI.
+ Xref MGI.
OMIM mapping confirmed by DO. [SN].
- nasopharynx carcinoma
+ nasopharynx carcinoma
@@ -4493,26 +4562,26 @@ OMIM mapping confirmed by DO. [SN].
- A myeloid neoplasm that is located_in the plasma cells in bone marrow.
+ A myeloid neoplasm that is located_in the plasma cells in bone marrow.
EFO:0001378
GARD:7108
ICD10CM:C90.0
ICD9CM:203.0
MESH:D009101
+ MIM:254500
NCI:C3242
- OMIM:254500
ORDO:29073
SNOMEDCT_US_2023_03_01:94705007
UMLS_CUI:C0026764
- myeloma
+ myeloma
disease_ontology
DOID:9538
- OMIM mapping confirmed by DO. [SN].
- multiple myeloma
+ OMIM mapping confirmed by DO. [SN].
+ multiple myeloma
@@ -4557,7 +4626,7 @@ OMIM mapping confirmed by DO. [SN].
- Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
+ Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
biological_process
@@ -4573,12 +4642,13 @@ OMIM mapping confirmed by DO. [SN].
physiological response to stimulus
biological_process
GO:0050896
-
+
-
+
+
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stimulus
@@ -4953,7 +5023,6 @@ Request that IAO either clarify these or change definitions not to use themPMID:11542087
PMID:11760965
PMID:12054223
- PMID:2112744
PMID:270744
PMID:32628106
PMID:36748408
@@ -4965,6 +5034,9 @@ Request that IAO either clarify these or change definitions not to use themPMID:9336922
eubacteria
ncbi_taxonomy
+ Bacteria (ex Cavalier-Smith 1987)
+ Bacteria Woese et al. 2024
+ Bacteriobiota
Monera
Procaryotae
Prokaryota
@@ -5002,7 +5074,6 @@ Request that IAO either clarify these or change definitions not to use themPMID:11542149
PMID:11760965
PMID:12054223
- PMID:2112744
PMID:25527841
PMID:270744
PMID:32628106
@@ -5013,6 +5084,7 @@ Request that IAO either clarify these or change definitions not to use themPMID:9336922
ncbi_taxonomy
Archaebacteria
+ Archaebiota
Mendosicutes
Metabacteria
Monera
@@ -5309,7 +5381,6 @@ Request that IAO either clarify these or change definitions not to use them
planned process
- planned process
Injecting mice with a vaccine in order to test its efficacy
A process that realizes a plan which is the concretization of a plan specification.
@@ -5833,7 +5904,6 @@ https://sourceforge.net/p/obi/obi-terms/738/
-
Anatomical entity that has mass.
@@ -5871,6 +5941,7 @@ https://sourceforge.net/p/obi/obi-terms/738/
AAO:0010841
AEO:0000000
+ BFO:0000004
BILA:0000000
BIRNLEX:6
CARO:0000000
@@ -5895,6 +5966,35 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A pathogen component in vaccine that contains only a part of the pathogen organism instead of the whole organism.
+ YH
+ vaccine component
+ part of pathogen organism in vaccine
+
+
+
+
@@ -6050,6 +6150,38 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing the whole of parts of genes encoding one or more vaccine antigen proteins.
+ YH
+ genetic vaccine
+ naked DNA vaccine
+ nucleic acid vaccine
+ vaccine
+ DNA vaccine
+
+
+
+
@@ -6090,13 +6222,25 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+ a vaccine component role that inheres in a recombinant vaccine vector as a vaccine component. The combination of a recombinant vaccine vector and a heterogenous protective antigen(s) inserted inside the vector for a recombinant vector vaccine.
+ YH,YL
+ role
+ recombinant vaccine vector role
+
+
+
+
-
+
@@ -6138,7 +6282,7 @@ https://sourceforge.net/p/obi/obi-terms/738/
-
+
@@ -6166,6 +6310,67 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ a processed material that is output of the vaccine preparation and part of a vaccine.
+ YH
+ cardinal part of vaccine
+ vaccine ingredient
+ vaccine component
+ vaccine component
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ Conjugate vaccine is vaccine that conjugates/links antigens to the molecules that form the outer coat of disease-causing bacteria to promote an immune response.
+ YH
+ vaccine
+ A conjugate vaccine is created by covalently attaching a poor (polysaccharide organism) antigen to a carrier protein (preferably from the same microorganism), thereby conferring the immunological attributes of the carrier on the attached antigen. --from wikipedia.
+ conjugate vaccine
+
+
+
+
@@ -6215,6 +6420,36 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A vaccine that is made from microbes that have been attenuated (weakened) in the laboratory so that they can't cause disease.
+ YH
+ attenuated vaccine
+ vaccine
+ live attenuated vaccine
+
+
+
+
@@ -6227,6 +6462,34 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ a vaccine component that originates from an organism such as a pathogen or a modified organism.
+ YH
+ vaccine component
+ pathogen organism component in vaccine
+
+
+
+
@@ -6318,6 +6581,41 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A vaccine that uses a modified virus or bacterium as the vector to deliver vaccine antigen(s) to the cells of the host body.
+ YH
+ vaccine
+ recombinant vector vaccine
+
+
+
+
@@ -6354,6 +6652,7 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
@@ -6473,6 +6772,35 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A vaccine that is composed of a purified protein(s) or other antigenic determinant(s) from a disease-causing organism. A subunit vaccine does not include the whole organism of a pathogen, so the subunits have less risk of causing adverse reactions.
+ YH
+ vaccine
+ subunit vaccine
+
+
+
+
@@ -6543,6 +6871,39 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A subunit vaccine that uses small peptide(s) as immunoepitopes.
+ Jie Zheng
+ YH
+ epitope vaccine
+ peptide-based synthetic vaccine
+ https://en.wikipedia.org/wiki/Peptide_vaccine
+ vaccine
+ peptide vaccine
+
+
+
+
@@ -6587,13 +6948,46 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ a vaccine component that uses a microbe (e.g., bacterium, virus, and parasitic organism) as a vector that is inserted with the DNA(s) of a heterologous protective antigen(s) to generate a "recombinant vector vaccine". The microorganism used as a vector generally has a stable non or low pathogenic phenotype for the species the vaccine is intended for.
+ YH
+ recombinant vector
+ WEB: http://en.wikipedia.org/wiki/Vaccine
+ WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf
+ WEB: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003856.pdf
+ vaccine component
+ recombinant vaccine vector
+
+
+
+
-
+
@@ -6629,6 +7023,29 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ A role that inheres in a material entity that becomes an ingredient of a vaccine.
+ YH
+ role
+ vaccine component role
+
+
+
+
@@ -6677,6 +7094,38 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ a vaccine against human papillomavirus infection
+ YH
+ vaccine
+ human papillomavirus vaccine
+ SNOMEDCT: 424519000
+ UMLS_CUI: C1512511
+
+
+
+
@@ -6689,6 +7138,19 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+ A viral vaccine that protects against infection with Papillomavirus.
+ YH
+ vaccine
+ Papillomavirus vaccine
+ MeSH: D053918
+
+
+
+
@@ -6714,6 +7176,39 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ the vaccine component that is used as antigen to produce an immune responce protect against the specific pathogen or disease.
+ This is a modified or partial form of the virus, bacteria or the toxin that causes the disease against which the vaccine protects. The vaccine antigen is altered from its original form so it no longer causes disease but it can produce an immune response.(Vaccine components FactSheet of NCIRS)
+ YL, YH
+ vaccine antigenic component
+ vaccine component
+ To create this term for cover some other vaccines such as cancer vaccine and so on.
+ vaccine antigen
+
+
+
+
@@ -6810,6 +7305,7 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
@@ -6838,6 +7334,7 @@ https://sourceforge.net/p/obi/obi-terms/738/
+
@@ -6890,6 +7387,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -7018,7 +7516,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
-
+
@@ -7046,6 +7544,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -7097,6 +7596,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -7215,6 +7715,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -8164,6 +8665,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -8715,6 +9217,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -9071,6 +9574,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -9110,6 +9614,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -9217,6 +9722,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -9268,7 +9774,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
-
+
@@ -9344,6 +9850,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10035,8 +10542,10 @@ However, running the reasoner takes time. As a way to reducing the time, I have
a grouping class for vaccines for specific diseases
+ Barry Smith, Oliver He, Jie Zheng, Charles Tapley Hoyt, Xingxian Li
+ https://github.com/vaccineontology/VO/issues/619
vaccine
- vaccine for disease
+ vaccine against disease
@@ -10083,8 +10592,21 @@ However, running the reasoner takes time. As a way to reducing the time, I have
A grouping class for vaccines for specific pathogens.
+ Barry Smith, Oliver He, Jie Zheng, Charles Tapley Hoyt, Xingxian Li
+ https://github.com/vaccineontology/VO/issues/619
vaccine
- vaccine for pathogen
+ vaccine against pathogen
+
+
+
+
+
+
+
+
+ a grouping class for vaccines for specific platforms
+ vaccine
+ vaccine by platform type
@@ -10105,6 +10627,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10159,6 +10682,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10213,6 +10737,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10267,6 +10792,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10321,6 +10847,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10375,6 +10902,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10427,6 +10955,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10471,6 +11000,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10565,6 +11095,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10619,6 +11150,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10723,6 +11255,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10773,6 +11306,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10827,6 +11361,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10874,6 +11409,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10921,6 +11457,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -10975,6 +11512,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11030,6 +11568,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11084,6 +11623,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11137,6 +11677,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11190,6 +11731,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11236,6 +11778,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11330,6 +11873,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11484,6 +12028,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11567,6 +12112,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11626,6 +12172,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11706,6 +12253,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11772,6 +12320,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11832,6 +12381,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11882,6 +12432,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11933,6 +12484,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -11984,6 +12536,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12038,6 +12591,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12106,6 +12660,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12159,6 +12714,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12211,6 +12767,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12257,6 +12814,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12310,6 +12868,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12385,6 +12944,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12507,6 +13067,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12562,6 +13123,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12677,6 +13239,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12730,6 +13293,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12783,6 +13347,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12836,6 +13401,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12888,6 +13454,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -12955,6 +13522,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13001,6 +13569,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13050,6 +13619,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13151,6 +13721,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13211,6 +13782,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13265,6 +13837,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13311,6 +13884,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13481,6 +14055,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13528,6 +14103,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13575,6 +14151,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13629,6 +14206,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13683,6 +14261,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13731,6 +14310,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13784,6 +14364,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13837,6 +14418,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13893,6 +14475,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -13947,6 +14530,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14107,6 +14691,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14200,6 +14785,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14247,6 +14833,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14294,6 +14881,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14393,6 +14981,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14499,6 +15088,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14554,6 +15144,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14610,6 +15201,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14719,6 +15311,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14805,6 +15398,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14852,6 +15446,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14904,6 +15499,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -14958,6 +15554,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15003,6 +15600,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15058,6 +15656,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15115,6 +15714,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15172,6 +15772,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15268,6 +15869,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15376,6 +15978,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15428,6 +16031,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15478,6 +16082,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15531,6 +16136,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15578,6 +16184,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15632,6 +16239,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15685,6 +16293,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -15734,6 +16343,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16011,6 +16621,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16065,6 +16676,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16112,6 +16724,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16206,6 +16819,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16253,6 +16867,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16300,6 +16915,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16347,6 +16963,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16463,6 +17080,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have
+
@@ -16510,6 +17128,7 @@ However, running the reasoner takes time. As a way to reducing the time, I have