forked from Dfam-consortium/RepeatMasker
-
Notifications
You must be signed in to change notification settings - Fork 0
/
SeqDBI.pm
executable file
·437 lines (297 loc) · 11.2 KB
/
SeqDBI.pm
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
#!/tools/bin/perl -w
##---------------------------------------------------------------------------##
## File:
## @(#) SeqDBI.pm
## Author:
## Robert Hubley <[email protected]>
## Description:
## A simple sequence database interface. Support for
## adding/removing and editing of sequences and simple
## description type annotations.
##
#******************************************************************************
#* Copyright (C) Institute for Systems Biology 2003-2004 Developed by
#* Arian Smit and Robert Hubley.
#*
#* This work is licensed under the Open Source License v2.1. To view a copy
#* of this license, visit http://www.opensource.org/licenses/osl-2.1.php or
#* see the license.txt file contained in this distribution.
#*
###############################################################################
# ChangeLog
#
# $Log$
#
################################################################################
#
## To Do:
#
# Provide a mechanism for providing alphabet distributions
# This will help with determining if all characters are
# masked. Also helps with GC content etc.
#
=head1 NAME
SeqDBI
=head1 SYNOPSIS
use SeqDBI;
Usage:
$mySeqDBI = $SeqDBI->new();
=head1 DESCRIPTION
A simple sequence database interface. Support for
adding/removing and editing of sequences and simple description
type annotations.
=head1 SEE ALSO
=over 4
FastaDB, RepeatMasker
=back
=head1 COPYRIGHT
Copyright 2004 Robert Hubley Institute for Systems Biology
=head1 AUTHOR
Robert Hubley <[email protected]>
=cut
#
# Module Dependence and Package Definition
#
package SeqDBI;
use strict;
use Carp;
use vars qw(@ISA @EXPORT @EXPORT_OK %EXPORT_TAGS $VERSION);
#
# Constants
#
use constant ReadOnly => 1;
use constant ReadWrite => 2;
require Exporter;
@ISA = qw(Exporter);
@EXPORT = qw();
@EXPORT_OK = qw(min max);
%EXPORT_TAGS = ( all => [ @EXPORT_OK ] );
#
# Version
#
my $VERSION = 0.1;
##-------------------------------------------------------------------------##
## Constructors
##-------------------------------------------------------------------------##
##-------------------------------------------------------------------------##
=head2 new()
Use: my $seqDB = SeqDBI->new();
Must be implemented by concrete classes.
=cut
##-------------------------------------------------------------------------##
sub new {
my $class = shift;
croak "Usage: \$seqDB = SeqDBI->new(); " if ( @_ != 0 );
# Create ourself as a hash
my $this = {};
# Bless this hash in the name of the father, the son...
bless $this, $class;
return $this;
}
##-------------------------------------------------------------------------##
## Public Methods
##-------------------------------------------------------------------------##
##-------------------------------------------------------------------------##
=head2 addSequence()
Use: my $seqID = addSequence( $obj, $name, $description, $sequence );
Add a sequence to the database.
=cut
##-------------------------------------------------------------------------##
sub addSequence {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 removeSequence()
Use: my removeSequence( $obj, $seqID );
Remove a sequence from the database.
=cut
##-------------------------------------------------------------------------##
sub removeSequence {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSeqCount()
Use: my $seqCount = &getSeqCount( $obj );
The number of sequences contained in this sequence database.
=cut
##-------------------------------------------------------------------------##
sub getSeqCount {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSeqLength()
Use: my $length = &getSeqLength( $obj, [$seqID] );
The sequence length of the entire database or of a
particular entry.
=cut
##-------------------------------------------------------------------------##
sub getSeqLength {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSeqLengths()
Use: my @sequenceLength = &getSeqLengths( $obj );
Get an array of sequence length values for all entries
in the database.
=cut
##-------------------------------------------------------------------------##
sub getSeqLengths {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getXNLength()
Use: my $xnLen = &getXNLength( $obj, [$seqID] );
Get the length of $seqID sequence minus the masking and
scaffold characters 'X' and 'N' respectively. If $seqID is
omited the value returned is the length of database
minus all "X" and "N" characters.
=cut
##-------------------------------------------------------------------------##
sub getXNLength {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getXNLengths()
Use: my @xnLengths = &getXNLengths( $obj );
Get the length of each sequence minus 'X' and 'N' characters
( case insensitive ). The values are returned in an array.
=cut
##-------------------------------------------------------------------------##
sub getXNLengths {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getGCLength()
Use: my $gcLen = &getGCLength( $obj, [$seqID] );
Get the length of $seqID sequence minus all characters
except "G" and "C" ( case insensitive ). If $seqID is
omited the value returned is the length of database
minus all characters except "G" and "C".
=cut
##-------------------------------------------------------------------------##
sub getGCLength {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getGCLengths()
Use: my @gcLengths = &getGCLengths( $obj );
Get the length of each sequence minus all characters
except "G" and "C" ( case insensitive ). The values
are returned in an array.
=cut
##-------------------------------------------------------------------------##
sub getGCLengths {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSubtLength()
Use my $subtLen = &getSubtLength( $obj, [$seqID] );
Get length of sequence minus the ambiguous characters.
=cut
##-------------------------------------------------------------------------##
sub getSubtLength {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getIDS()
Use my @seqIDs = &getIDS( $obj );
Get an array of all sequence identifiers in the database.
=cut
##-------------------------------------------------------------------------##
sub getIDs {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getDescriptors()
Use my @descriptors = &getDescriptors( $obj );
Get an array of all sequence descriptions contained in the database.
=cut
##-------------------------------------------------------------------------##
sub getDescriptors {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getDescription()
Use: my $desc = &getDescription( $obj, $seqID);
Get the sequence description text for a given $seqID.
=cut
##-------------------------------------------------------------------------##
sub getDescription {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 compact()
Use: my &compact();
Compact database. Provide a means to remove "holes" or space inefficiencies
in the database.
=cut
##-------------------------------------------------------------------------##
sub compact {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSequence()
Use: my $seqString = &getSequence( $seqID );
Get the sequence string for a given seqID.
=cut
##-------------------------------------------------------------------------##
sub getSequence {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 getSubstr()
Use: my $sequence = &getSubstr( $obj, $seqID, $offset, [$length] );
Get a portion of a sequence from the database. If the $length parameter
is left the return value will be everything following the $offset.
=cut
##-------------------------------------------------------------------------##
sub getSubstr {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
##-------------------------------------------------------------------------##
=head2 setSubstr()
Use: my &setSubstr( $obj, $seqID, $offset, $length, $newSeq);
Replace a portion of a sequence with a new sequence. If the
$newSeq is smaller or larger than the specified length the
database's sequence will be contracted or expanded accordingly
( as the perl substr function ).
=cut
##-------------------------------------------------------------------------##
sub setSubstr {
die "Interface SeqDBI does not implement this function\n"
. "Try instantiating an implementation of this interface\n"
. "instead!\n";
}
1;