Upscaling very large images

[gtnbssn]

I have images that are already pretty large (i.e. satellite imagery the like you can get from sentinel2 and similar sources) that I am trying to upscale.

Are there recommendations on how to upscale images that are already extremely large?

I am running into issues with one image at the moment.

The image is a png, dimensions are 10696 × 7165 and weight is 67.4 MB.

My understanding is that Real-ESRGAN tiles the image and works on the tiles so the size of my file shouldn't matter so much, however i do run into an error after a moment of processing this file:
fish: Job 1, './realesrgan-ncnn-vulkan -i /Us…' terminated by signal SIGBUS (Misaligned address error)
(This is on a m2max mac with 32GB of RAM.)

I can open this image in regular image software without issues.

I also tried on a much larger (4GB) file and got a different error : decode image failed.

[gtnbssn]

Just tried the same image on a Windows machine. Processing crashed at the exact same spot (41.17%) but with no error message here. (This machine has 128GB of RAM so I expect this wouldn't be a memory issue?)

[gtnbssn]

It is definitely (probably) a size thing. I tried a slightly bigger file and it fails at a slightly earlier percentage.

Any suggestions?